ライフサイエンスコーパス: cellular level

1 y, as well as their uptake mechanisms at the cellular level.

2 rus-host interactions in this species at the cellular level.

3 stfertilization fruit growth proceeds at the cellular level.

4 echanical and calcium heterogeneities at the cellular level.

5 organismal thermal stress translated to the cellular level.

6 result in elevated superoxide levels at the cellular level.

7 NHE3 expression at the surface membrane and cellular level.

8 ial (AP) and I(Kr) current properties at the cellular level.

9 ccurate quantitative marker of cancer at the cellular level.

10 pivotal role in transmitting signals at the cellular level.

11 s, syncytia and host vascular tissues at the cellular level.

12 e the gene target is highly regulated at the cellular level.

13 ural abnormalities in retinal disease at the cellular level.

14 formation about the Alzheimer pathology on a cellular level.

15 artially mediated by glial components at the cellular level.

16 l composition of tissues and cells on a (sub)cellular level.

17 to define the pathways of renal injury at a cellular level.

18 l transection of the trigeminal nerve at the cellular level.

19 IgG converge to target gut microbiota at the cellular level.

20 ilitates isolation and manipulation at a sub-cellular level.

21 on was used to examine these pathways at the cellular level.

22 rk for the development of E/I balance at the cellular level.

23 ur results show its use at the organelle and cellular level.

24 importance to understand certain diseases at cellular level.

25 ion of distinct disease subtypes down to the cellular level.

26 and rate dependence were investigated at the cellular level.

27 al processes underlying our estimator at the cellular level.

28 ble to measure gene expression variations at cellular level.

29 nnot elucidate fiber type differences at the cellular level.

30 ead post-transcriptional compensation at the cellular level.

31 ully with quantitative kinetic detail at the cellular level.

32 ophysiological properties of Re neurons at a cellular level.

33 tic drug responses to toxic reactions at the cellular level.

34 derived exosomes on mouse endothelium at the cellular level.

35 promote negative Ca i2+-->Vm coupling at the cellular level.

36 re conditions for stable oscillations at the cellular level.

37 unction and reducing arrhythmogeneity at the cellular level.

38 obe biological dynamics, particularly at the cellular level.

39 a limited understanding these functions at a cellular level.

40 eract with nanostructured materials on a sub-cellular level.

41 lant tissues with resolution approaching the cellular level.

42 nuclear localized GPS1 report on GAs at the cellular level.

43 on, and attenuated the Warburg effect at the cellular level.

44 control of plant shoot morphogenesis at the cellular level.

45 f PM that best account for its toxicity at a cellular level.

46 ntwine with those of metabolic stress at the cellular level.

47 eneration or other AD-related pathology on a cellular level.

48 lomeres and remains poorly understood at the cellular level.

49 ions about how this disease manifests at the cellular level.

50 a similar type of proteostatic stress at the cellular level.

51 effects of sChoK inhibitors can vary at the cellular level.

52 1 protein and residual DDX11 function at the cellular level.

53 mor in vivo on immuno-PET and ex vivo at the cellular level.

54 tic, molecular, biochemical, structural, and cellular levels.

55 ns the cognitive, systems, network, and even cellular levels.

56 tion in mice at the whole animal, organ, and cellular levels.

57 the structural, biophysical, biochemical and cellular levels.

58 the joint exploration of data from multiple cellular levels.

59 tRIIA/ActRIIB antibody, at the molecular and cellular levels.

60 1(loxP/loxP) ) were studied at the organ and cellular levels.

61 tion of specific histological information at cellular levels.

62 ogeneity at the genomic, transcriptional and cellular levels.

63 and interactions with drugs at molecular and cellular levels.

64 hanobiological processes at cellular and sub-cellular levels.

65 mechanisms in a context-dependent fashion at cellular levels.

66 ding of thermosensation at the molecular and cellular levels.

67 egulating the immune system at molecular and cellular levels.

68 o insecticidal activity at the molecular and cellular levels.

69 to interact with both filament types at the cellular level?

70 At the cellular level, a lattice-based energy driven stochastic

71 At cellular level, accumulated damages are computed using a

72 t that genetic or chemical modulation of the cellular levels/activity of USP13 affects unperturbed ce

73 At cellular levels, adrenergic signaling increases dendrite

74 However, an full understanding of cellular-level allostasis is far from developed.

75 At the cellular level, alphaII spectrin deficiency resulted in

76 At the cellular level alternans is observed as beat-to-beat alt

77 At the cellular level, an upregulation of ERK signaling during

78 a series of quantitative measurements at the cellular level and a biophysical simulation approach to

79 eterogeneity of nanoparticle delivery at the cellular level and allow the derivation of simple, yet p

80 se surfaces are an extreme topography on the cellular level and have become useful tools for perturbi

81 ntly unclear how this is orchestrated at the cellular level and how cell fate is affected by severe t

82 pounds showed far better results both at the cellular level and inside the live worm.

83 ansgene brain expression was sporadic at the cellular level and most prominent in hippocampal neurons

84 n of dominance, however, is nonlinear at the cellular level and obeys the principles underlying metab

85 The individual cellular level and quantitative Polyphosphate (PolyP)-me

86 Because of its high resolution at the cellular level and sensitivity, optical imaging is highl

87 etween maturation of dendritic arbors on the cellular level and the loss of diffusion anisotropy with

88 ofiber stretch as a growth stimulant at both cellular level and tissue-level.

89 How the cellular levels and activity of HO2 are regulated remain

90 Tight regulation of the cellular levels and catalytic activities of HO1 and HO2

91 ly captures 3D nanoparticle distributions at cellular levels and demonstrates the distinct cellular u

92 red by a lack of methods to manipulate their cellular levels and metabolic fate with appropriate spat

93 Cellular levels and stability of intermediate signaling

94 ials suggesting the possibility of important cellular-level and molecular differences between animals

95 nal modifications, spatial regulation at the cellular level, and TGFBR availability at the cell surfa

96 trongly implicated in RA at both genetic and cellular levels, and PAD inhibitors have shown therapeut

97 At the cellular level, APTX deficiency impairs mitochondrial mo

98 asks in mammalian biology, their skills on a cellular level are deemed limited, mainly consisting in

99 molecular mechanisms regulating aging at the cellular level are largely unknown.

100 entific evidence that genetic effects at the cellular level are much stronger than those at the organ

101 The disease-modifying aspects of DBS at a cellular level are not fully understood, and the key que

102 tion underlying cellular anisotropies at the cellular level are reviewed, with an emphasis on Rho-fam

103 architecture and function on the network and cellular level are well documented in epilepsy.

104 cts with all three GLI proteins and that its cellular levels are regulated by SHH.

105 functional capacity on systemic, organ, and cellular levels, as well as critical clinical skills to

106 At the cellular level, astrocytes and oligodendrocyte progenito

107 On a cellular level, ATP-consuming reactions are suppressed,

108 ghts into clinical seizure dynamics based on cellular-level biophysical properties.

109 At the cellular level, Bmal1 protein bound to Atm, Brca1, and B

110 ersal response to energy availability at the cellular level, both in thermoacidophiles, and in other

111 impedes the regeneration capabilities at the cellular level, but it is not clear if the different ons

112 circuits whose functions are balanced at the cellular level by excitatory glutamatergic pyramidal neu

113 s organismic phenotype was paralleled at the cellular level by increased fatty acid uptake via a cave

114 ive immunity is unexpectedly mirrored at the cellular level by the capacity of human innate-like CXCL

115 KEY POINTS: At the cellular level cardiac hypertrophy causes remodelling, l

116 On a cellular level, CDC led to diminished cell death, improv

117 At the cellular level, Cj-P1 induced more C. jejuni invasion an

118 At the cellular level, clock regulation is established by a sel

119 greater sensitivity to changes in E2 at the cellular level contribute to PMD.

120 alized, and that the tissue structure at the cellular level correlates with the mechanical performanc

121 ulation at the transcriptomic, molecular and cellular levels, creates opportunities to uncover the un

122 tissue engineered constructs to control the cellular-level damage and cell-cell distance in individu

123 At the cellular level, DCA alleviated NE-associated ileal epith

124 asive clinical tools capable of establishing cellular-level diagnoses.

125 At the cellular level, direction is determined by the passive,

126 At the cellular level, disseminating E-cadherin-negative cells

127 Similar dynamics at cellular levels drive biological processes and generate

128 autism-iPSCs diverge from control-iPSCs at a cellular level during early stage of neurodevelopment.

129 The cellular-level effects of low/high frequency oscillating

130 At the cellular level, Epr3 expression delineates progression o

131 dent with ventral furrow formation, and at a cellular level, extension occurs via convergent cell nei

132 ow these key proteins are specialized in the cellular level for the initial social behaviour during p

133 cal structures is essential to understanding cellular-level function in both healthy and diseased sta

134 , a unified understanding of its role at the cellular level has not been achieved.

135 At the cellular level, heart muscle cells generate higher force

136 -cell assays offer an opportunity to resolve cellular level heterogeneity, e.g., scRNA-seq enables si

137 th condition; its spatial arrangement at the cellular level, however, was not dependent on rRNA synth

138 At the cellular level, HSV-1 consistently downregulated the exp

139 At the cellular level, if combined with RBC models, the generat

140 feact induces dose-response artefacts at the cellular level, impacting stress fibre dynamics and acti

141 on; tumors evolve by similar mechanisms at a cellular level in a tissue.

142 atial information on TAM infiltration at the cellular level in entire lungs.

143 tic resonance microscopy (MRM) images at the cellular level in isolated mammalian brain tissues were

144 e report the distribution of platinum at the cellular level in non-small cell lung cancer (NSCLC) exp

145 s the spatiotemporal events occurring at the cellular level in order to predict leukocyte transmigrat

146 l-time tracking of drug flow and flux on the cellular level in situ.

147 Functional activity maps at the cellular level in specific behaviors, including sleep, a

148 At the cellular level in the hippocampus, ISR inhibition (i) re

149 central FGFR/beta klotho (Klb) system at the cellular level in the mouse, with relevant comparisons t

150 At the cellular level in the retrotrapezoid nucleus (RTN), we f

151 At the cellular level in these animals, microglia depletion red

152 ogens and reveals disease progression at the cellular level in vivo.

153 ssue has been investigated at both organ and cellular levels in mice with cardiomyocyte-specific dele

154 tructure of the RPE at the tissue level, but cellular level information may provide valuable RPE biom

155 level information from diagnostic images and cellular-level information from genomics are needed.

156 On a cellular level, inhibition of GBA2 activity in isolated

157 approach links molecular mechanisms to known cellular-level iPSC-CM phenotypes, as shown by comparing

158 t-stimulated blood feeding in Anopheles At a cellular level, Ir21a is essential for the detection of

159 d interpreting heterogeneous mixtures at the cellular level is a critical problem in genomics.

160 hese intricate processes interconnect at the cellular level is of paramount clinical importance for o

161 g of its spatial and temporal sensing at the cellular level is still an open challenge.

162 modifying chromatin but what this means at a cellular level is unclear.

163 on the functional coupling of states at the cellular level is what determines macroscopic growth cha

164 to understand diseases and therapies at the cellular level, it is crucial to have an accurate unders

165 haematopoiesis dominate at both the gene and cellular levels, jointly accounting for one-third of dif

166 s scales such that patterned disorder at the cellular level leads to the emergence of organism-level

167 At the cellular level, loss of CDC42 function in brain endothel

168 At a cellular level, loss of MIC60 disrupts synaptic structur

169 At the cellular level, lymphopenia was present in patients with

170 This increased susceptibility at the cellular level manifests as increased susceptibility to

171 earch and regenerative medicine; yet, on the cellular level, many steps are still poorly understood.

172 Additionally, at a cellular level, MCs act as potent effector cells of comp

173 This was one of the first cellular-level mechanisms described for MSI.

174 e discuss recent progress in elucidating the cellular-level mechanisms underlying inter-brain neural

175 ry deprivation, thus closing the gap between cellular-level mechanisms, system-level linguistic and s

176 At the cellular level, mHTT aggregates were more often encounte

177 At the cellular level, mitochondrial dysfunction starts at the

178 On the cellular level, mitochondrial function is critical for n

179 he likelihood of coinfection at the host and cellular levels, mixing and assembly of heterologous gen

180 Providing resolution at cellular-level morphology, RCM imaging combined with mos

181 atasets, opening the possibility of studying cellular level network organization of neural systems an

182 At the cellular level, neuronal communication occurs through ax

183 At the cellular level, Nick4 is coexpressed with Nfr5 in root h

184 The cellular level of c-di-AMP in Streptococcus pyogenes is

185 However, EHV-1 reduced the cellular level of expression of tyrosine kinase 2 (TYK2)

186 ese results indicate that an increase in the cellular level of FA can trigger mitochondrial DNA doubl

187 The cellular level of HPr is approximately 150 times higher

188 EHV-1 did not alter the cellular level of Janus-activated kinase 1 (JAK1) at any

189 like the wild type, but fail to elevate the cellular level of PIP3, the product used to signal downs

190 1 regulates the subcellular localization and cellular level of the potassium channel Kv3.1 in cells.

191 tion of TWIST1, and consequently reduces the cellular level of TWIST1 and its downstream signaling.

192 apacity of melanoma cell lines and increased cellular levels of 5-carboxylcytosine, the last intermed

193 Cellular levels of 5fTHF are regulated by a futile cycle

194 We measured the cellular levels of 6 classes of histone modifications, a

195 dysfunction could alter the redox state and cellular levels of acetyl-CoA, resulting in altered hist

196 ear polarity by controlling localization and cellular levels of active Rac.

197 ,6-bisphophatase; therefore, the decrease in cellular levels of citrate would stimulate glycolysis an

198 ransporter NaCT in HepG2 cells and decreases cellular levels of citrate.

199 family of enzymes whose activity depends on cellular levels of cyclic AMP).

200 We found that reduction in cellular levels of GCC2 or M6PR impaired PS-ASO release

201 e depletion of USP25 from adipocytes reduces cellular levels of GLUT4 and concomitantly blunts the ab

202 ctivity and is required for attaining proper cellular levels of H3K27me3.

203 s a direct inhibitor of FBXW7, affecting the cellular levels of its substrates.

204 riboswitches have exploited the coupling of cellular levels of ligand and divalent metal ions to tig

205 Moreover, PIKfyve deficiency increases the cellular levels of lysosomal proteins.

206 contributes to PG enlargement by regulating cellular levels of MepS, a cross-link-specific hydrolase

207 GlcFuc disaccharide, and in markedly reduced cellular levels of MIC2.

208 cap and DXO as a deNADding enzyme modulating cellular levels of NAD(+)-capped RNAs.

209 a stabilization of p27, suggesting that the cellular levels of NEDD8 and RBX1 affect CRL activity.

210 ysLT1 antagonist and is sufficient to reduce cellular levels of NF-kappaB and calpain-2 and secreted

211 t demonstrates that O. tsutsugamushi reduces cellular levels of NOD-, LRR-, and CARD-containing 5 (NL

212 or in the cells, significantly decreased the cellular levels of Nrf2, NQO1 and HO-1 as well as the ra

213 uitable for use under conditions of variable cellular levels of O2.

214 In summary, the cellular levels of oligomeric proteins such as Hsp20 are

215 tion of selenium was initiated by increasing cellular levels of organic, but not inorganic, forms of

216 The three proteins regulate the cellular levels of phosphatidylinositol 3-kinase-related

217 he localization of Vps13-GFP is altered when cellular levels of PI3P are decreased indicating its tra

218 Cellular levels of ribonucleoside triphosphates (rNTPs)

219 We conclude that the cellular levels of Srx and TXNDC5 may be useful as bioma

220 ly, most mutant strains accumulate wild-type cellular levels of the major pilin PilA, but not extrace

221 Cellular levels of the versatile second messenger cyclic

222 iral DNA and RNA polymerases with respect to cellular levels of their nucleotide substrates.

223 nd the importance of maintaining appropriate cellular levels of thiamin vitamers for the plant's meta

224 However, it was claimed that a decrease in cellular levels of this lipid upon receptor activation d

225 egradation, a process crucial for regulating cellular levels of this vital, but cytotoxic, cofactor.

226 enhanced multiple proteasome activities and cellular levels of ubiquitinated proteins by activating

227 Here, we describe functional units, at a cellular level, of a compound eye from the base of the C

228 At the cellular level, Opn3-KO brown adipocytes cultured in dar

229 ive and only provide kinetics information at cellular level or in discrete time.

230 This framework links molecular mechanisms to cellular-level outputs by revealing unique subsets of mo

231 Thus, at functional, network, and cellular levels, physiological estradiol influences the

232 ogical and (epi)genetic modifications at the cellular level, plants also employ external strategies t

233 At the cellular level, pregabalin inhibited glutamatergic synap

234 Here, we report cellular-level preservation of tendon- and cartilage-lik

235 es of condensates and IDPs/IDRs in important cellular level processes and molecular functions in bact

236 In selected species, we assessed cellular-level processes shaping nectary size.

237 Here, we reveal receptor- and cellular-level properties consistent with receptor activ

238 ssing, but not before that, by a fundamental cellular-level property: the thresholded firing rate non

239 The molecular and cellular level reaches of the metabolic dysregulations t

240 circuits provides a powerful way to engineer cellular-level recognition.

241 At the cellular level, reduced oil body mobilization and enlarg

242 o pre-clinical or human biodistribution with cellular level resolution for NMs starting only from in

243 access thousands of cortical points at near-cellular-level resolution.

244 rray capable of achieving real-time, stable, cellular level-resolution electrophysiological mapping i

245 ther discussed emergent questions concerning cellular level responses to nanoparticle-associated cues

246 ological targets, but their signaling at the cellular level results from a complex interplay between

247 e emergent dynamics and interactions between cellular-level Rho GTPase activity and contractility and

248 At the cellular level, shade antagonizes phyB signaling by trig

249 ls induced changes at both the community and cellular level, shifting community composition, enzyme a

250 By establishing a morphogen gradient at the cellular level, signals become constrained.

251 At a cellular level, stem cell dysfunction and attrition appe

252 Unfortunately, many of the cellular-level studies reporting signs of criticality we

253 At a cellular level, studies of diverse cell types in vitro a

254 These results reveal the presence of potent cellular-level subnetworks within the orbitofrontal cort

255 s biological effects at both the systems and cellular level that together suggest oligodendrocyte-mye

256 Recent studies have shown that on the cellular level the frequency organization of A1 is more

257 At the cellular level, the different social behaviors of M. xan

258 At the cellular level, the occurrence of irregular-type action

259 locking the potential of implants capable of cellular-level therapeutic targeting.

260 At the cellular level, there was an impaired ANXA1 production b

261 At the cellular level, thermogenesis is achieved through increa

262 (MD), molecular Brownian dynamics (BD), and cellular-level thermokinetic modeling of microtubules.

263 At the cellular level, these tumours are composed of a mixture

264 At the cellular level, they do so through signaling pathways.

265 notypes ultimately derive from events at the cellular level, this connection is essential to building

266 Thus, at the molecular and cellular level, this mouse line provides a valuable tool

267 At the cellular level, this wave of electrical activity corresp

268 hitecture, a process that is achieved at the cellular level through mechanotransduction-mediated fine

269 epends on synaptic input, is mediated at the cellular level through the recruitment of signaling path

270 l gauge" that regulates energy supply at the cellular level to a sensing and signaling pathway that r

271 rates the power of chemical screening at the cellular level to address specific proteinopathies and t

272 e acute effect, but how ketamine acts at the cellular level to sustain this anti-depressive function

273 on leads to aberrant development and, at the cellular level, to defects in the nuclear pore and nucle

274 ovide the first visualization of DMSP at sub-cellular levels, tracking the fate of a stable sulfur is

275 However, probing their functions at the cellular level typically has invoked the complete deleti

276 were investigated by RNA studies and on the cellular level using immunofluorescence and microscopy.

277 majority of the observed alterations at the cellular level using in situ sequencing on mouse and hum

278 years, cannabinoids have been studied at the cellular level using tissue explants with conflicting re

279 ned binding characteristics on molecular and cellular levels using SPR, ELISA, and flow cytometry.

280 At the cellular level, VHH6 was able to alter the response of e

281 Here, we expand this cellular level view of MSI by focusing on the principle

282 At the cellular level, we demonstrate that targeting of p38delt

283 d elucidate its underlying mechanism, at the cellular level, we established an in vitro model of OIHP

284 At the cellular level, we found that HIFalpha was required for

285 At the cellular level, we found that the inhibitory action exer

286 At the sub-cellular level, we incorporate a detailed kinetic model

287 At a cellular level, we observe dysregulation of key pathways

288 At the cellular level, we observed a striking impairment of cla

289 In vitro techniques at the molecular and cellular levels were now applied to assess their functio

290 y adversely impact recovery from ARDS at the cellular level, whereas MSCs may not be therapeutically

291 the cochlea can be studied at the organ and cellular level with LSFM, and this same material can be

292 e level of seed germination, but it did at a cellular level with reduced cell expansion in the hypoco

293 Detection of biological features at the cellular level with sufficient sensitivity in complex ti

294 tudy examined resistance to infection at the cellular level with the most prevalent human cell-tropic

295 This was mechanistically observed at the cellular level, with ET-1-induced, DAF-FM-measurable end

296 was to visualize biological processes on the cellular level, with the additional dimension of topogra

297 gative strategy to regulate autophagy at the cellular level within the TME.

298 This work establishes a bridge to cellular-level work in animals on the one hand, and the

299 ns have been identified at the molecular and cellular levels, yet how these phenomena affect cortical

300 ogical organisms at both the macroscopic and cellular levels, yet it has been considerably less obser