ライフサイエンスコーパス: certainty

1 adverse events (AEs) slightly increase (low certainty).

2 tive risk, 0.82; 95% CI, 0.48-1.41; very low certainty).

3 und (low certainty) to 124 541 US$ (moderate certainty).

4 [95% CI 6.82-22.61], I(2)=0%, RD 36.5%, high-certainty).

5 troke (RR, 1.17 [CI, 1.05 to 1.30]; moderate certainty).

6 RR 1.21 [0.87-1.69], I(2)=0%, RD 0.03%, low-certainty).

7 ctions: 1.55 [0.96-2.50], I(2)=28%, moderate-certainty).

8 ons on any coronal surface (moderate to high certainty).

9 observed 24 hours after doses 1 and 8 (>95% certainty).

10 r; 95% CI, 0.83 d fewer to 0.73 d more; high certainty).

11 s compared to fluoride with moderate to high certainty.

12 inical and parasitological response with 92% certainty.

13 hose genotypes that Impute2 imputed with low certainty.

14 cling 3% GMPs acquiring malignancy with near certainty.

15 ortex, a region reflecting outcome value and certainty.

16 indicated lesion conspicuity and diagnostic certainty.

17 but at the same time, spoke with a sense of certainty.

18 ther AD or FTD and the individual diagnostic certainty.

19 nsistent or recognized with less statistical certainty.

20 halamic nucleus in the modulation of outcome certainty.

21 es do not exhibit a high level of diagnostic certainty.

22 natomical and taxonomic provenance with 100% certainty.

23 F), linkage disequilibrium (LD) and genotype certainty.

24 onged to Kent to be identified with absolute certainty.

25 th 2SD cut-offs may offer greater diagnostic certainty.

26 ns to a single variant with greater than 50% certainty.

27 I, making it difficult to identify them with certainty.

28 g this progression cannot be determined with certainty.

29 ctile and air stimulus with high to moderate certainty.

30 predicted to clear 109 parasites/mL with 95% certainty.

31 oney samples by geographical origin with 87% certainty.

32 neficial for tactile stimulus, with moderate certainty.

33 cial for all 3 stimuli with high to moderate certainty.

34 ccurately identify the benign condition with certainty.

35 c COPD (conditional recommendation, moderate certainty); 2) we suggest that patients with chronic sta

36 rm NIV (conditional recommendation, very low certainty); 3) we suggest not initiating long-term NIV d

37 resolution (conditional recommendation, low certainty); 4) we suggest not using an in-laboratory ove

38 atients (73%) with GBS (90% Brighton level 1 certainty), 7 (18%) with encephalitis, 3 (8%) with trans

39 abnormalities and clinician-rated diagnostic certainty about ASD) in later childhood.

40 Participants' certainty about expectations predicted the extent of pai

41 Moreover, participants' certainty about expectations predicted the magnitude of

42 but are dependently regulated by individual certainty about expectations.

43 that are dependently regulated by individual certainty about expectations.SIGNIFICANCE STATEMENT Posi

44 problem, the confidence in the evidence, the certainty about how much the public values the main outc

45 treatment period of 4-12 weeks, but very low certainty about the effects of using topical glucocortic

46 rd prediction errors also codes the animal's certainty about the presence of the stimulus and the tem

47 Dorsal regions additionally tracked decision certainty across both types of evaluation.

48 ee systems were declining strongly with high certainty (all in the Indo-Pacific region) and seven wer

49 ], I(2)=0%, risk difference [RD] 15.1%, high-certainty), anaphylaxis frequency (incidence rate ratio

50 ing the Withdrawal Agreement, which provides certainty and continuity in legal relations while the Po

51 of the journey that starts with measurement certainty and ends with policy uncertainty.

52 oser to 45 degrees during conditions of high certainty and that this bias was reduced when sensory ev

53 erence, -0.19 [95% CrI, -0.37 to -0.09]; low certainty) and face mask noninvasive ventilation (RR, 0.

54 e, -0.12 [95% CrI, -0.25 to -0.05]; moderate certainty) and high-flow nasal oxygen (RR, 0.76 [95% CrI

55 tive risk, 0.64; 95% CI, 0.34-1.22; moderate certainty) and hospital length of stay (mean difference,

56 nula may reduce ICU length of stay (moderate certainty) and hospital length of stay (moderate certain

57 tive risk, 0.46; 95% CI, 0.30-0.70; moderate certainty) and postextubation respiratory failure (relat

58 avitated facial/lingual carious lesions (low certainty) and that 38% silver diamine fluoride solution

59 R] 2.72 [1.57-4.72], I(2)=0%, RD 12.2%, high-certainty), and epinephrine use (RR 2.21 [1.27-3.83], I(

60 1.92 [1.00-3.66], I(2)=0%, RD 5.7%, moderate-certainty), and non-anaphylactic reactions (vomiting: RR

61 ng NIV (conditional recommendation, very low certainty); and 5) we suggest NIV with targeted normaliz

62 single causal variant with greater than 95% certainty, and an additional 27 associations to a single

63 ng: RR 1.79 [95%CI 1.35-2.38], I(2)=0%, high-certainty; angioedema: 2.25 [1.13-4.47], I(2)=0%, high-c

64 ere it would have been previously found with certainty, appearing instead within the third box, to wh

65 aux wines, which can be used with reasonable certainty as specific parameters for identifying regiona

66 ence of these contacts cannot be stated with certainty because of technical limitations, but the poss

67 The evidence was of moderate certainty because of unclear or high risk of bias in all

68 s BLAST might discourage attempts at greater certainty because single runs represent a major resource

69 starts decreasing cannot be calculated with certainty before the turning point is actually attained;

70 tive risk, 0.52; 95% CI, 0.30-0.91; very low certainty), but had no effect on mortality (relative ris

71 er of transmetalation vs C-H activation with certainty, but the results suggest that BF3.OEt2 promote

72 urthermore, the generation of high structure certainty by consideration of (i) mass accuracy of the p

73 nces are private information, not known with certainty by the other politicians with whom they are ne

74 timal experiment to identify parameters with certainty can be easily designed without any prior infor

75 5% CI, 2.16 d fewer to 0.21 d more; moderate certainty) compared with conventional oxygen therapy, ho

76 ainty) and hospital length of stay (moderate certainty) compared with noninvasive ventilation.

77 ng-term NIV (conditional recommendation, low certainty).Conclusions: This expert panel provides evide

78 Our results therefore challenge the 'high certainty' consensus regarding decreasing water resource

79 ls adjusted for age at diagnosis, diagnostic certainty, diagnostic delay, site of onset, and score on

80 -4.45; 95%CI -5.39 to -3.51), and QoL (high certainty) (DLQI; MD -4.03; 95% CI -5.56 to -2.5) and de

81 In all certainty, edible mushrooms can be referred to as a "sup

82 Until greater certainty emerges on what protections should be afforded

83 ls (RR 1.04; 95% CI 0.42-2.56), and very low-certainty evidence for an increased risk of anti-tissue

84 There was low-certainty evidence for no difference in risk of HLA-DQ2

85 There was low-certainty evidence for the risk of anti-Saccharomyces an

86 Moderate certainty evidence found an increased risk of CeD in pat

87 There was moderate-certainty evidence from 2 trials (1550 participants) tha

88 There was moderate-certainty evidence from 5 trials (1915 participants) tha

89 One study provided very-low-certainty evidence of an association between increased p

90 For VTE, moderate-certainty evidence showed a probable association with ol

91 For bleeding, moderate-certainty evidence showed a probable association with ol

92 Low-certainty evidence showed inconclusive effects of dual v

93 Moderate-certainty evidence showed increased odds of persistent o

94 Low-certainty or very low-certainty evidence showed that continuous passive motion

95 Very low-certainty evidence showed that cryotherapy was associate

96 At the median follow-up of 1 year, high-certainty evidence showed that dual therapy was associat

97 Moderate-certainty evidence showed that electrotherapy reduced th

98 Low-certainty evidence showed that omega-3 long-chain polyun

99 In patients with peanut allergy, high-certainty evidence shows that available peanut oral immu

100 Low-certainty evidence suggested increased risk for persiste

101 Very-low-certainty evidence suggested that interventions that inc

102 h more severe COVID-19 disease, and moderate-certainty evidence suggests no association between use o

103 High-certainty evidence suggests that ACEI or ARB use is not

104 There was low-certainty evidence that acupuncture improved pain (mean

105 Two studies provided very-low-certainty evidence that adding sitters reduced falls.

106 d 2 studies, respectively, provided moderate-certainty evidence that adjusting panel size for case mi

107 reported a systematic review that found high-certainty evidence that angiotensin-converting enzyme in

108 Study-level meta-analyses provide high-certainty evidence that heparin reduces the risk of symp

109 Eight studies provided low-certainty evidence that increasing panel size was associ

110 Three studies each provided low-certainty evidence that increasing panel size was associ

111 Eight studies provided moderate-certainty evidence that interventions that included vide

112 There was moderate-certainty evidence that reduced salt intake decreased th

113 We found moderate-to-low certainty evidence that the use of high-flow nasal cannu

114 intake is low) is warranted unless new high-certainty evidence to the contrary from robust clinical

115 ) and has little to no effect on height (low certainty evidence) and cognition (moderate certainty ev

116 dible interval [CrI] -0.09 to 0.28; moderate certainty evidence) or height (0.07 cm, 95% CrI -0.10 to

117 r per 1000 children, 95% CrI -48 to 32; high certainty evidence), cognition measured by short-term at

118 ht (0.07 cm, 95% CrI -0.10 to 0.24; moderate certainty evidence), little to no difference in proporti

119 5% confidence interval (CI), 0.65-3.11]; low certainty evidence), nicotinamide (2 trials, 60 particip

120 attendance (1% higher, 95% CI -1 to 3; high certainty evidence), or mortality (one fewer per 1000 ch

121 100 point scale, 95% CI -0.56 to 0.14; high certainty evidence), school attendance (1% higher, 95% C

122 ID-19 illness in a large community (moderate-certainty evidence).

123 pain (Grade: conditional recommendation; low-certainty evidence).

124 gh effect sizes were small (low- to moderate-certainty evidence).

125 al function (conditional recommendation; low-certainty evidence).

126 adol (Grade: conditional recommendation; low-certainty evidence).

127 patients, RR 17.09 [95% CI, 4.22-69.26]; low certainty evidence).

128 r cognition (conditional recommendation; low-certainty evidence).

129 ular disease outcomes (very low- to moderate-certainty evidence).

130 manent teeth, respectively (low- to moderate-certainty evidence).

131 pants, RR 0.62 [95% CI, 0.45-0.85]; moderate certainty evidence).

132 ewer per 1000 children, 95% CI -3 to 1; high certainty evidence).

133 certainty evidence) and cognition (moderate certainty evidence).

134 al function (conditional recommendation; low-certainty evidence).

135 ntestinal and neurologic harms (all moderate-certainty evidence).

136 ated with more severe COVID-19 illness (high-certainty evidence).

137 (Grade: conditional recommendation; moderate-certainty evidence).

138 tion (Grade: strong recommendation; moderate-certainty evidence).

139 racy, and school enrolment owing to very low certainty evidence.

140 We found that certainty (Experiment 1) and congruency (Experiment 2) b

141 erence, -0.32 [95% CrI, -0.60 to -0.16]; low certainty), face mask noninvasive ventilation (RR, 0.76

142 The diagnostic certainty for a positive lesion was scored on a 3-point

143 a short-term treatment period, with moderate certainty for elemental diets, low certainty for empiric

144 moderate certainty for elemental diets, low certainty for empiric 2-, 4-, and 6-food elimination die

145 ials was judged to be insufficient or of low certainty for most harm outcomes.

146 (64.3%) met the criteria for high diagnostic certainty for PML ('definite PML' or 'probable PML').

147 from GBS meeting levels 1 or 2 of diagnostic certainty for the Brighton Collaboration, with proof of

148 There is very low certainty for the effect of proton pump inhibitors in pa

149 to fluoride (3.93; 0.34-7.53) with moderate certainty; for air stimulus, arginine (2.22; 1.45-2.99),

150 First, haplotypes may not be inferred with certainty from genotype data.

151 valuation) approach was used to evaluate the certainty in evidence and generate actionable recommenda

152 GRADE methodology was used to rate the certainty in findings.

153 subgroups of patients will allow for greater certainty in its cost-effectiveness.

154 eported more and smaller lesions with higher certainty in PET hybrid imaging than in conventional ima

155 neural consequences of manipulating stimulus certainty in the context of orientation processing.

156 There is very low certainty in the effects of multiple other medical treat

157 nd Evaluation) approach was used to rate the certainty in the estimated effects and the strength of r

158 The methodologists appraised the certainty in the evidence (i.e., the quality of evidence

159 each question, which included appraising the certainty in the evidence (i.e., the quality of evidence

160 Moderate to low certainty in the evidence indicates that available fecal

161 There is moderate certainty in the evidence that topical glucocorticostero

162 t of Diagnostic Accuracy Studies II, and the certainty in the evidence using the GRADE (Grading of Re

163 Certainty in the evidence was judged to be very low, bec

164 k-of-bias assessments, and assessment of the certainty in the evidence with the Grading of Recommenda

165 st proportion of false-negative results (low certainty in the evidence).

166 s (burdens, adverse effects, and costs), the certainty in the evidence, and the feasibility and accep

167 specificity range, 0.90-0.99) with moderate certainty in the evidence.

168 tories collectively, generating a dataset of Certainty-Index (CI) maps to reflect the likelihood of a

169 actions: 1.36 [1.02-1.81], I(2)=0%, moderate-certainty; lower tract respiratory reactions: 1.55 [0.96

170 her, 95% CI 0.16 lower to 0.27 higher; GRADE certainty: moderate).

171 (relative risk, 1.16; 95% CI, 0.86-1.57; low certainty), mortality (relative risk, 1.12; 95% CI, 0.82

172 seven were declining strongly but with less certainty (mostly reptile and amphibian groups).

173 fixation potentiation was not overridden by certainty of an imminent pursuit trial but rather was im

174 The certainty of available evidence supporting the use of se

175 elated scenarios representing, respectively, certainty of diagnosis, multiple causes of symptoms, jau

176 ghed desirable and undesirable consequences, certainty of estimates, feasibility, and acceptability.R

177 l effects compared to fluoride with moderate certainty of evidence (SMD; 95% CI): potassium + stannou

178 rienced methodology team for determining the certainty of evidence and the direction and strength of

179 d using the Mixed Method Assessment Tool and certainty of evidence evaluated according to the GRADE C

180 The certainty of evidence for glycemic control by subgroup w

181 es (OR 1.69 [95% CI 0.83-3.41] with very low certainty of evidence for the five observational studies

182 o [OR] 1.15 [95% CI 0.75-1.78] with very low certainty of evidence for the four observational studies

183 l studies and 0.62 [0.18-2.14] with very low certainty of evidence for the RCT) or congenital anomali

184 studies and 1.10 [0.07-17.65] with very low certainty of evidence for the RCT).

185 However, the certainty of evidence for this recommendation is conside

186 tion (1.94, 1.31-2.86; I(2)=76.6%), although certainty of evidence from these studies was graded as l

187 rce has assessed, discussed, and debated the certainty of evidence on the basis of Grading of Recomme

188 using a fixed-effect model and assessed the certainty of evidence using the GRADE (Grading of Recomm

189 We assessed certainty of evidence using the Grading of Recommendatio

190 Certainty of evidence was assessed within each study usi

191 Certainty of evidence was evaluated by using the GRADE (

192 The certainty of evidence was evaluated using the Confidence

193 The overall certainty of evidence was explored using the Grading of

194 The certainty of evidence was graded moderate for body weigh

195 Certainty of evidence was moderate to very low.

196 Certainty of evidence was rated low or very low for all

197 The certainty of evidence was rated very low to moderate.

198 0.58, 95% CI 0.46-0.73, P < 0.001; moderate certainty of evidence) and 5 years (risk ratio 0.68, 95%

199 k ratio 0.68, 95%CI 0.46-0.99, P = 0.04; low certainty of evidence).

200 Given the overall low certainty of evidence, definitive recommendations will n

201 ings are limited by the very low to moderate certainty of evidence.

202 nd Evaluation (GRADE) approach to assess the certainty of evidence.

203 recommendations were conditional due to low certainty of evidence.

204 matter to women and provided a rating of the certainty of evidence.

205 e high risk of bias and moderate to very low certainty of evidence.

206 velopment, and evaluation was used to assess certainty of evidence.

207 cted data, assessed risk of bias, and graded certainty of evidence.

208 y diagnosing anaphylaxis due to the very low certainty of evidence.

209 val (CI) -2.01 to -0.49, P = 0.001; moderate certainty of evidence] which persisted at 3 years, but t

210 The appearance of certainty of model estimates is seductive when the world

211 ad reduction is required before there is 95% certainty of observing any hypoxic area reduction betwee

212 ore likely to evolve when males gain greater certainty of paternity or when future mating opportuniti

213 this utility increased nonlinearly with the certainty of receiving the reward.

214 or levels, although heterogeneity limits the certainty of the effect on risk factors.

215 gn, execution, and reporting, leading to low certainty of the evidence about true test performance, w

216 y and using rigorous systems to evaluate the certainty of the evidence and to move from evidence to r

217 Certainty of the evidence for the outcomes ranged from m

218 w, systematic reviews and assessments of the certainty of the evidence have not been published.

219 ations on outcomes that matter to women, and certainty of the evidence is rated for each.

220 es have assessed, discussed, and debated the certainty of the evidence on the basis of the Grading of

221 duplicate and independently and assessed the certainty of the evidence using the Grading of Recommend

222 The certainty of the evidence varied from very low to high a

223 The risk of bias and the certainty of the evidence were assessed using GRADE.

224 ate the risk of bias and GRADE to assess the certainty of the evidence.

225 vidence around harmful alcohol use limit the certainty of these findings.

226 Certainty of this finding was downgraded to a moderate l

227 ared evidence profiles and assessed quality (certainty) of evidence relevant to the key questions acc

228 clinically meaningful improvements (moderate certainty) of the UAS7 (MD -11.05; 95%CI -12.87 to -9.24

229 t in clinically meaningful improvement (high certainty) of the urticaria activity score (UAS)7 (mean

230 mputations, leading to a subjective sense of certainty or error (C2, consciousness in the second sens

231 Low-certainty or very low-certainty evidence showed that con

232 or beliefs, each weighted according to their certainty (or precision).

233 tive risk, 0.93; 95% CI, 0.57-1.52; moderate certainty), or ICU length of stay (mean difference, 0.05

234 tive risk, 1.12; 95% CI, 0.82-1.53; moderate certainty), or postextubation respiratory failure (relat

235 The subjective sense of certainty, or confidence, in ambiguous sensory cues can

236 usoidal gratings) and three manipulations of certainty (orientation bandwidth, contrast, and duration

237 Additionally, individuals may seek certainty over uncertainty.

238 .001), image quality (p < 0.001), diagnostic certainty (p < 0.001), and radiation exposure (6.1 +/- 0

239 The effects of other factors were of lower certainty, predominantly due to small numbers and potent

240 We assessed certainty (quality) of evidence by the GRADE approach.

241 CI -3.2 to -1.1) does not increase (moderate certainty) quality of life (QoL) (Dermatology Life Quali

242 Interestingly, the strength of these certainty-related connectivities was also significantly

243 5%CI -3.22 to -0.81) and decreases (moderate certainty) rescue medication use (MD -1.68; 95%CI -2.95

244 5% CI -5.56 to -2.5) and decreases (moderate certainty) rescue medication use (MD -2.04; 95%CI -3.19

245 A-positive disease, number of lesions, and a certainty score, were documented.

246 1.42; 0.3% absolute risk reduction, moderate certainty), serious complications (relative risk, 0.87;

247 The diagnostic certainty showed only a very slow and mild decline, with

248 (RR 2.21 [1.27-3.83], I(2)=0%, RD 4.5%, high-certainty) similarly during build-up and maintenance (p(

249 w cover conditions in finer detail with more certainty than those obtained from Visible Infrared Imag

250 e used P-scores, which measure the extent of certainty that a treatment is better than another treatm

251 , and 6-food elimination diets, and very low certainty that allergy-based testing dietary elimination

252 The USPSTF concludes with moderate certainty that behavioral counseling interventions have

253 The USPSTF concludes with moderate certainty that behavioral counseling interventions reduc

254 herefore, the USPSTF concluded with moderate certainty that combined estrogen and progestin has no ne

255 For adults, there is high certainty that dupilumab decreases SCORAD (MD -30,72; 95

256 The USPSTF concludes with moderate certainty that interventions to support breastfeeding ha

257 The USPSTF concludes with moderate certainty that primary care-feasible behavioral interven

258 The USPSTF concludes with moderate certainty that providing or referring pregnant or postpa

259 n adults, the USPSTF concludes with moderate certainty that screening by asking questions about unhea

260 evidence, the USPSTF concludes with moderate certainty that screening for AAA in men aged 65 to 75 ye

261 The USPSTF concludes with moderate certainty that screening for AAA in men aged 65 to 75 ye

262 evidence, the USPSTF concludes with moderate certainty that screening for and treatment of asymptomat

263 The USPSTF concludes with moderate certainty that screening for and treatment of asymptomat

264 The USPSTF concludes with moderate certainty that screening for asymptomatic bacterial vagi

265 The USPSTF concludes with high certainty that screening for colorectal cancer in averag

266 The USPSTF concludes with moderate certainty that screening for HBV infection in adolescent

267 The USPSTF concludes with moderate certainty that screening for HCV infection in adults age

268 herefore, the USPSTF concluded with moderate certainty that screening for obesity in children and ado

269 ftware methods are complex, making it a near certainty that some implementations will contain errors.

270 The USPSTF concludes with moderate certainty that the harms of screening for AAA in women a

271 The USPSTF concludes with high certainty that the magnitude of benefit of PrEP with ora

272 The USPSTF concludes with high certainty that the net benefit of screening for HIV infe

273 herefore, the USPSTF concluded with moderate certainty that the overall net benefit is moderate for c

274 tice was made when there was a high level of certainty that the recommendation would do more good tha

275 We found with certainty that the wild-type hTERT promoter sequence doe

276 herefore, the USPSTF concludes with moderate certainty that there is a substantial net benefit of scr

277 roorganisms, confidence to a near-scientific certainty that they cannot transfer their transgenic gen

278 Although we cannot identify with certainty the timing and location of tuberculosis transm

279 NAION it is still impossible to predict with certainty the visual outcome of a sequential contralater

280 the absence of complete data and statistical certainty: there is a place for well-informed judgments,

281 All other studies had insufficient certainty to obtain even tentative conclusions about eff

282 tiveness ratio ranged from 28 500 pound (low certainty) to 124 541 US$ (moderate certainty).

283 population were calculated by inverting 99% certainty tolerance limits.

284 ending on severity threshold for statistical certainty, up to 19% of this clinical cohort had CFC sev

285 angioedema: 2.25 [1.13-4.47], I(2)=0%, high-certainty; upper tract respiratory reactions: 1.36 [1.02

286 r (odds ratio 1.28, 95% CI 1.09, 1.50; GRADE certainty: very low).

287 n primary visual cortex (V1) and manipulated certainty via stimulus contrast (100% vs 3%).

288 ium muris and Giardia lamblia, with over 92% certainty was achieved.

289 tigators assessed risk of bias, and evidence certainty was determined by consensus.

290 sessed using the Cochrane tool, and evidence certainty was evaluated using the Grades of Recommendati

291 Evidence certainty was evaluated using the Grading of Recommendat

292 d with conventional oxygen therapy, however, certainty was limited by imprecision.

293 To assess certainty, we created tables containing a summary of the

294 e, -0.06 [95% CrI, -0.15 to -0.01]; moderate certainty) were associated with a lower risk of mortalit

295 e, -0.11 [95% CrI, -0.27 to -0.01]; moderate certainty) were associated with lower risk of endotrache

296 f cells, it is impossible to determine, with certainty, where the features are coincident in the geno

297 for stroke (RR, 0.80 [CI, 0.67 to 0.96]; low certainty), whereas calcium plus vitamin D increased the

298 ields CA1, 3, and 4 could be identified with certainty, while CA2 was tentatively identified as a sma

299 and inactive C. parvum oocysts with over 90% certainty, whilst also detecting damaged and/or excysted

300 for Euro 4, 5, and 6a/b diesel cars with 80% certainty within a +/-1 g NO per kg fuel tolerance margi