ライフサイエンスコーパス: chemistry

1 esized proteins were then labeled via 'click chemistry'.

2 e of anion or by solution versus the surface chemistry.

3 for target molecule synthesis and medicinal chemistry.

4 s as the foundation for future plutonium MOF chemistry.

5 eference is a challenging goal in host-guest chemistry.

6 compounds are key building blocks in organic chemistry.

7 tivity and selectivity has a long history in chemistry.

8 lenty of research opportunities in materials chemistry.

9 lidation and characterization of the surface chemistry.

10 viously been used to indicate O(3) formation chemistry.

11 y is a powerful strategy in transition metal chemistry.

12 reactions, collectively known as photoclick chemistry.

13 H group would be of great value to medicinal chemistry.

14 ay have important implications for prebiotic chemistry.

15 envalue and spectral problems in physics and chemistry.

16 ations in medical diagnostics and analytical chemistry.

17 EDL) at a liquid-solid interface in physical chemistry.

18 eactions are the most important phenomena in chemistry.

19 m thanks to the rapid development of radical chemistry.

20 s in Tagish Lake cannot be ascribed to fluid chemistry.

21 ucture, spectroscopy, computation, and model chemistry.

22 ative and qualitative problems in analytical chemistry.

23 approach in the field of volatile analytical chemistry.

24 l-spirooxindoles for direct use in medicinal chemistry.

25 us fields of materials science and medicinal chemistry.

26 C-H bonds is one of the Grails of synthetic chemistry.

27 is hence a useful tool for synthetic organic chemistry.

28 H(-) concentrations promote the C-C coupling chemistry.

29 energy demanding, and value-added, oxidative chemistry.

30 anging from materials science to biophysical chemistry.

31 omentum in biochemistry and (supramolecular) chemistry.

32 substructures to be considered in medicinal chemistry.

33 challenge in the field of synthetic organic chemistry.

34 reactions of transition-metal organometallic chemistry.

35 eralization rates, despite their contrasting chemistry.

36 reaction partners and expanding their known chemistry.

37 es that undergo sulfur(VI) fluoride exchange chemistry.

38 ons currently play a central role in polymer chemistry.

39 alization of scaffolds relevant to medicinal chemistry.

40 dition reactions is of widespread utility in chemistry.

41 , IR, EPR, and NMR spectroscopy; and quantum chemistry.

42 OA formation due to indoor ozone-monoterpene chemistry.

43 of protein targets and dynamic combinatorial chemistry.

44 ectrodes originate from silica-silicon redox chemistry.

45 he prime focus for contemporary carbohydrate chemistry.

46 takes place by time-consuming solution phase chemistry.

47 data without any prior assumptions on their chemistries.

48 er, in particular for the more divergent XNA chemistries.

49 Topological quantum chemistry(4) has enabled the understanding of and the se

50 inding, without the need for complex surface chemistries acting as blocking agents.

51 pective reviews the biological and medicinal chemistry advances over the past 3 decades with an empha

52 late (PEGDA) aqueous droplets for local PDMS chemistry alteration resulting in significant softening

53 Water chemistry analysis and size fractionation sampling were

54 cohort of UAE nationals, employing clinical chemistry analysis, 1D (1)H NMR and mass spectroscopy (F

55 ing the complex reaction mechanism of sulfur chemistries and for exploring the rich material properti

56 s to evaluate the relationship between liver chemistries and liver histology using data from the CyNC

57 c or (44)Sc/(47)Sc-would guarantee identical chemistries and pharmacologic profiles.

58 server-based tool (ICBM-OCEAN, Institute for Chemistry and Biology of the Marine Environment, Oldenbu

59 Stemming from the foundational concepts in chemistry and biology, these methodologies enable visual

60 idation elevates the importance of nocturnal chemistry and biomass burning as a global source of OOA.

61 st owing to their potential for solar-driven chemistry and biomedical applications.

62 The review offers a platform in which the chemistry and biomedical research communities can access

63 pands the known scope of pyridazine/pyrazine chemistry and can be applied toward the synthesis of nov

64 ecosystem in regional and global atmospheric chemistry and climate.

65 and versatile functional group in medicinal chemistry and drug discovery.

66 hen diets on performance, egg quality, blood chemistry and egg lipid peroxidation was studied.

67 Characterization of microstructure, chemistry and function of energy materials remains a cha

68 t mechanistic understanding of DMS oxidation chemistry and geostationary satellite cloud imagery data

69 benes are important intermediates in organic chemistry and have been widely applied in various types

70 pplication in (photo)catalysis, bioinorganic chemistry and materials science.

71 ed noteworthy concerns in organic functional chemistry and materials.

72 Here, we report on the chemistry and microbial community of the highly reducing

73 our fundamental understanding of the surface chemistry and nucleation behavior of iron(III) (hydr)oxi

74 undamental knowledge for understanding xenon chemistry and physics mechanisms for the possible deep-E

75 asic science research, involving solid-state chemistry and physics, has been at the center of this en

76 ward deciphering the connections between the chemistry and physiology of lipid peroxidation.

77 on the role of sulfur structure, carbon host chemistry and porosity, and electrolytes in establishing

78 sent a new cofactor paradigm in bioinorganic chemistry and pose countless outstanding questions.

79 oscale catalysts that can enable Fenton-like chemistry and produce reactive radicals from hydrogen pe

80 use significant differences in wheat protein chemistry and shikimic acid levels, especially when appl

81 The chemistry and short lifetimes of metal-based anti-cancer

82 tedious methodologies, with complex surface chemistry and small sizes.

83 alysis-occupies a unique position in organic chemistry and stands as an eminent challenge for mechani

84 he photoactive layer by changing the surface chemistry and suppressing methylammonium loss.

85 score the connection between protein physico-chemistry and the coevolutionary couplings that can be d

86 Also, because of nonlinear production chemistry and titration of ozone in winter, reduced nitr

87 ble isotopes as a proxy for paleoatmospheric chemistry and use Hg isotope data from 2.5 billion-year-

88 blood metabolomes, blood proteomes, clinical chemistries, and data from wearable devices.

89 ly, homoenolate chemistry, beta-keto radical chemistry, and acid-catalyzed ring-opening, as well as a

90 uding organometallic chemistry, bioinorganic chemistry, and cluster science.

91 ls are ubiquitous scaffolds in many areas of chemistry, and efficient methods for their synthesis are

92 will be widely used in fine chemistry, green chemistry, and industrial chemical processes.

93 ecular scaffolds, metallochaperones, radical chemistry, and novel and unique biosynthetic intermediat

94 nsion of lambda-orthogonal tandem photoclick chemistry, and the innovative use of these unique tools

95 f reducing organic particle mass through ALW chemistry, and these benefits extend beyond the eastern

96 A dynamic covalent chemistry approach was used for the stereoselective synt

97 structure in a graphene liquid cell by a wet-chemistry approach.

98 established surface display or combinatorial chemistry approaches for the discovery of therapeutic pe

99 overy has used natural product and synthetic chemistry approaches to generate libraries of compounds,

100 embrane-bound oligosaccharides with specific chemistries are known to promote tight adhesion between

101 New atom-economical alternatives to Wittig chemistry are needed to construct olefins from carbonyl

102 p metal chemistry, polymerization, and green chemistry are showcased in this Review.

103 y that aerosol pH and atmospheric multiphase chemistry are strongly affected by the pervasive human i

104 orms of stimuli-responsive, dynamic covalent chemistries as a means to transition their behavior from

105 This process leads to distinctive fluid chemistries as molecular hydrogen (H(2) ) and hydroxyl i

106 , combining several orthogonal cross-linking chemistries as well as improvements in search algorithms

107 ential of native MS coupled to gas-phase ion chemistry as a means of facilitating rational repurposin

108 s show future implications of changing ocean chemistry as well as of the resulting abilities of marin

109 tropospheric relevance associated with these chemistries, as well as the physical conditions resultin

110 s from the chemical landscape of the dynamic chemistry at the junction.

111 on for the way spatial confinement of Fenton chemistry at the nanoscale can significantly enhance the

112 s study, we introduce a new dynamic covalent chemistry based on siloxane equilibrium exchange into th

113 A click chemistry-based flux assay reveals that necrocytosis pro

114 t-used bond-construction method in medicinal chemistry because the chemistry is reliable and draws up

115 tivity and preventing unwanted radical-based chemistry before the K2 [Fe(4)S(4)] cluster substrate is

116 e main reactivity modes, namely, homoenolate chemistry, beta-keto radical chemistry, and acid-catalyz

117 inorganic chemistry including organometallic chemistry, bioinorganic chemistry, and cluster science.

118 try, including atmospheric and environmental chemistry, biology, electrochemistry, and solar energy c

119 portant in the context of, e.g., atmospheric chemistry, biophysics, and electrochemistry.

120 initially produced by irreversible cracking chemistry, but, as thermal maturity increases, the isoto

121 earning models in the field of computational chemistry by considering selected studies of electronic

122 s of existing real-time dPCR instruments and chemistries, by extracting more information from data to

123 Back to our terrain-we ask "Quantum Chemistry, * ca. 2020?" Then move to examples of AI affe

124 Since the latter are mostly based on quantum chemistry calculations, we also provide a short introduc

125 ed evolution of RT function for any template chemistry called compartmentalized bead labelling and de

126 We undertook a focused medicinal chemistry campaign to simultaneously preserve potent and

127 Traditional wet-chemistry catalyst synthesis often requires complex proc

128 Similarly, linker chemistry (cleavable versus stable) altered activity, bu

129 l-mediated cross-couplings in modern organic chemistry, coupling reactions involving nitrogenous hete

130 and the discovery of RTs for the orphan XNA chemistries D-altritol nucleic acid and 2'-methoxyethyl

131 re the subject of so-called dynamic covalent chemistry (DCC).

132 uable component for machine-driven medicinal chemistry design workflows.

133 roach using structural elucidation to enable chemistry design/SAR development.

134 The use of other particle chemistries did not grossly affect the tumor targetabili

135 nd prototypes realized to expedite medicinal chemistry discovery cycles.

136 vide a guide to the overall approach to flow chemistry, discussing the key parameters for the design

137 hostile nature of the environments involved, chemistry does occur in space.

138 Additional factors, such as drug chemistry, drug formulations, different routes of admini

139 tions in material science and supramolecular chemistry due to their aggregation-induced emission (AIE

140 s that some tropospherically-relevant non-OH chemistry (e.g. VOC photolysis in UVA and UVB) is not su

141 In practice, all medicinal chemistry efforts and eventual commercialization have re

142 Chemistry efforts on the scaffold revealed a dynamic str

143 iconducting properties with tailored surface chemistry, elastic mechanical properties and chemical st

144 rganic reaction systems for developing green chemistry electrosynthesis methods.

145 ble appetite for iron, only recently has the chemistry emerged to exploit this altered state therapeu

146 Synthetic chemistry enables a bottom-up approach to quantum inform

147 junction with ligand-directed acyl imidazole chemistry enables covalent labeling of AMPA-type glutama

148 Bioorthogonal click chemistry ensures fast and highly selective attachment o

149 vidence that other, more abundant saccharide chemistries exhibit similar behavior.

150 This chemistry expands the known scope of pyridazine/pyrazine

151 c microporous framework membranes, where the chemistry, fabrications, and differences among these mem

152 so possible to use the reaction in synthetic chemistry for general formation of amide bonds.

153 Here, we show an important extension of this chemistry for the activation of tyrosine residues that p

154 ic scaffolds and also covered the design and chemistry for the conjugation of TLR2 agonists to antige

155 ay pave the way for the use of gas-phase ion chemistry for the generation of complex molecular struct

156 (i.e. lactate dehydrogenase), via EDC/S-NHS chemistry, for the fabrication of a Bio-Nano-PEDOT-based

157 on based on real-time feedback on the system chemistry from in situ X-ray absorption spectroscopy.

158 er secondary organic aerosol (SOA) formation chemistry from naturally emitted isoprene.

159 in diverse applications including synthetic chemistry, gas valorization, and greenhouse gas remediat

160 Here, the diversity of chemistries, geometries, and properties found in chiral

161 een reagent that will be widely used in fine chemistry, green chemistry, and industrial chemical proc

162 the sulfonylated products via organolithium chemistry has been achieved.

163 ful tool in asymmetric synthesis, while flow chemistry has begun its rise as a new enabling technolog

164 Radical chemistry has gained considerable momentum in the field

165 Modern computational chemistry has provided information not previously availa

166 lication of informatics to solve problems in chemistry, has increasingly influenced prediction of act

167 Although solvent effects in supramolecular chemistry have been recognized for a long time, the uniq

168 strated tremendous utility in modern organic chemistry; however, their application for the synthesis

169 marks a big leap forward in metal alkylidyne chemistry in general.

170 this study, we investigate changes in blood chemistry in NiV-infected Syrian hamsters that survived

171 and, another cause of deviation from ambient chemistry in OFR is that some tropospherically-relevant

172 ental conditions and processes involved with chemistry in space yields complex populations of materia

173 VOCs and nitrogen oxides and hence the ozone chemistry in the east and south coast.

174 ontext of ligand-based and metal-based redox chemistry in the enzymatic oxygen atom transfer reaction

175 lexes show unique structure and coordination chemistry including an unusual tridentate coordination e

176 a wide array of subdisciplines of inorganic chemistry including organometallic chemistry, bioinorgan

177 fied titanium in predominantly two different chemistries, including metallic and titanium dioxide (Ti

178 cause of their implications in many areas of chemistry, including atmospheric and environmental chemi

179 platform that has broad applicability to SET chemistry, including radical-radical cross-coupling, Min

180 (mu-H)](-1) by pulse EPR revealed that redox chemistry induces significant changes in Fe-C covalency

181 th pore sizes lower than 2 nm based on their chemistry: inorganic microporous framework membranes, or

182 zed from single step, high yielding (82-92%) chemistry involving a 4-hydroxycoumarin 4 + 1 cycloaddit

183 rrence of quantum mechanical tunneling (QMT) chemistry involving atoms heavier than hydrogen was cons

184 Herein, we have thoroughly studied the chemistry involving dual-emission persistent luminescenc

185 Cluster chemistry involving Y, lanthanides (Ln, from La to Lu),

186 Selenium (Se) redox chemistry is a determining factor for its environmental

187 intermolecular hydrogen atom transfer (HAT) chemistry is at play, rather than classical Norrish hydr

188 The fast ET and PT chemistry is attributed to the delocalized electronic st

189 hlight that brown carbon formation from iron chemistry is efficient under a wide range of aerosol phy

190 This unanticipated flavin chemistry is not restricted to Etf-Bcd but certainly occ

191 on the impact of topology in other areas of chemistry is provided at the end of the article.

192 on method in medicinal chemistry because the chemistry is reliable and draws upon large and diverse s

193 ic piperidines-building blocks for medicinal chemistry-is developed.

194 For medicinal chemistry, it would be very useful to derive mechanistic

195 and in many places are still, ubiquitous in chemistry laboratories.

196 and used to solve problems in the fields of chemistry, materials science, and biochemistry.

197 Similar chemistry may be enabled by nickel(II) hydrides that sto

198 This chemistry may therefore contribute to brown carbon produ

199 ips) by synergistically integrating covalent chemistry-mediated EV capture/release, multimarker antib

200 rtance for the simplification of cloud water chemistry models.

201 At its core, a flow chemistry module is a stable set of conditions - traditi

202 mers of considerable interest to the organic chemistry, molecular spectroscopy, and astrochemistry co

203 esent a comprehensive picture connecting the chemistries of hydroxyl (OH) and hydroperoxy radicals, o

204 of reductive cycloaddition reactivity in the chemistry of 2-phosphaethynolate.

205 situ method to control the residual lithium chemistry of a high-nickel lithium layered oxide, Li(Ni(

206 However, the galvanic replacement chemistry of alkali metals has rarely been explored.

207 pective of the published essential medicinal chemistry of cannabidiol (CBD) provides evidence that th

208 turnover is not dominantly controlled by the chemistry of carbon inputs, but rather by restrictions o

209 ernative methods exist to perform the unique chemistry of diazomethane, these suffer from diminished

210 the results suggest that the photosensitizer chemistry of HULIS in ambient atmospheric aerosols is un

211 e shown the potential of the photosensitizer chemistry of humic acid, as a proxy for humic-like subst

212 periments coupled to the S(IV)-autooxidation chemistry of isoprene, 3-methyl-2(5H)-furanone, and 4-me

213 es limitations bound by sequence-by-ligation chemistry of ISS.

214 his review briefly describes the solid state chemistry of many of these materials.

215 ry of hierarchical controls on the inorganic chemistry of melanosomes from fossil vertebrates from ni

216 and suggests that the actinide coordination chemistry of mineral surface mimics, such as silsesquiox

217 Characterization of the turnover chemistry of Pgp3 reveals cell wall D,D-endopeptidase an

218 es have opened new avenues for the medicinal chemistry of PS-ASOs and research on all elements of the

219 stable soil carbon by thermally altering the chemistry of soil organic matter (SOM), thereby reducing

220 The chemistry of specially activated carbon pai-systems unde

221 and temperature of melanging on the volatile chemistry of the finished chocolate.

222 lculations further illuminate the comparable chemistry of the unzipping.

223 However, the structure and chemistry of the vdW interfaces are less known.

224 ontribute significantly to the excited-state chemistry of these molecules.

225 ade has engendered a renewed interest in the chemistry of these species.

226 ion mechanisms, especially regarding radical chemistry of this system, remain elusive.

227 y interpretableand is faithful to underlying chemistry of transcription factor binding to DNA.

228 our understanding of proton-dependent redox chemistry of transition metal oxide surfaces.

229 e applicable to a variety of block copolymer chemistries on multigram scales with excellent mass reco

230 discriminate between highly similar polymer chemistries or identify heterogeneities within individua

231 s, reduced light availability, altered water chemistry or any combination of these.

232 pared with wild type, without altering blood chemistry or displaying hyperthermia or muscle rigor.

233 pective takes the position that carbohydrate chemistry, or glycochemistry, has reached three crossroa

234 reversible covalent bonding, supramolecular chemistry, or polymers with phase-separated morphologies

235 chemicals remains a central theme in organic chemistry owing to the key roles of amines in synthesis,

236 w probing tool for sampling sensitivities to chemistry parameters during a three-dimensional (3-D) si

237 ace-based HCHO/NO(2) to interpret local O(3) chemistry, particularly with the new-generation satellit

238 ely, this MS(n) platform paired with ion/ion chemistry permitted identification of major, and some mi

239 the most creative minds across the fields of chemistry, pharmacology, physiology, and behavior in the

240 solids that are relevant in diverse areas of chemistry, physics, and materials science.

241 Our results suggest that quinone binding and chemistry play a key role in the coupling mechanism of c

242 Medicinal chemistry plays a fundamental and underlying role in che

243 ganic synthesis, low-valent main-group metal chemistry, polymerization, and green chemistry are showc

244 evelopment, focusing on how physical organic chemistry principles have guided probe design.

245 elatively low cost, and acquittance to green chemistry principles.

246 ocks with potential application in medicinal chemistry programs as p-substituted aniline bioisosteres

247 ing survey data obtained from five medicinal chemistry programs in the Midwest and recent alumni of t

248 compared to the engineered enzyme and click chemistry reagents.

249 Taking into account the bulk chemistry reconstructed from the FeNi(Cu) alloy, we prop

250 ueous solutions, and the complex interfacial chemistry remains elusive.

251 rstanding of these phenomena and their redox chemistry remains incomplete.

252 throughput efficiency and the new sequencing chemistry removes limitations bound by sequence-by-ligat

253 ave been playing a vital role in atmospheric chemistry research for seven decades.

254 application areas for electronic modules in chemistry research include construction of simple detect

255 ation of electronics and computer science in chemistry research.

256 or higher adverse events were abnormal blood chemistry results (33 [15%] of 221 patients in the treos

257 Catenated cages represent chemistry's challenging synthetic targets because a thre

258 Chemistry's streak of creation provides in that conjoine

259 d by any researcher having basic biology and chemistry skills in ~3 d.

260 ent developments toward innovative medicinal chemistry strategies based on continuous flow systems co

261 Medicinal chemistry strategies used to derisk bioactivation will b

262 Consequently, for decades medicinal chemistry studies aiming at developing skin depigmenting

263 des a timeline of PARP biology and medicinal chemistry, summarizes the pathophysiological processes i

264 Here, the material chemistries that facilitate the 3dTM-SSCs generation thr

265 n widely employed to understand the emergent chemistry that arises from the formation of the metal-or

266 0.1) up to 16 mug/m(3)) with complex PM(0.1) chemistry that included 40-60 wt % organic carbon, 10-15

267 ed to be concentration-dependent interfacial chemistry that only occurs among closely contact ion-pai

268 aloids and provides insights into the unique chemistry that plants use to generate complex, bioactive

269 particularly with attention to the medicinal chemistry that will be unavoidably required for the furt

270 mportant tools to the field of bioorthogonal chemistry, there is a need for new approaches to synthes

271 ples are taken from the field of atmospheric chemistry, they were selected because of their broad rel

272 tandem mass spectrometry with gas-phase ion chemistry to achieve both differentiation and quantifica

273 ique combination of length, flexibility, and chemistry to act as an effective latch for the phenylala

274 Furthermore, applying this chemistry to bacteriophage allows facile chemical modifi

275 uptake by cells allowing extracellular click chemistry to be performed.

276 But for such plasmon-driven chemistry to be precisely understood and modeled, the cr

277 introduced sulfur-triazole exchange (SuTEx) chemistry to demonstrate the triazole as an effective LG

278 e encoding DNA tag relegating DEL compatible chemistry to dilute aqueous environments.

279 ends the dichloroimidazolidinedione-mediated chemistry to encompass the C-C bond cleavage reaction.

280 Using colloidal chemistry to exquisitely control nanoparticle size, we f

281 ishes the importance of applying SOMC to MOF chemistry to get well-defined single site catalyst on MO

282 precursors for supramolecular and materials chemistry to illustrate the utility of the synthesized c

283 nvironment of microdroplets allows different chemistry to occur.

284 e desirable in experiments ranging from cold chemistry to searches for physics beyond the Standard Mo

285 Here we explore selective radical chemistry to target aromatic residues applying C-H (18)F

286 nces in our understanding of the fundamental chemistry underlying the materials used in bioelectronic

287 Related chemistry was also observed with C(5)F(5)N, which result

288 nBDC is stabilized, topotactic intercalation chemistry was used to demonstrate the feasibility of bro

289 Thiol-maleimide chemistry was utilised to covalently ligate the Group B

290 on air monitoring and simulated atmospheric chemistry, we used a spatiotemporal model to estimate 3-

291 CFE will be able to benefit flow chemistry when it is both compatible with nonaqueous sol

292 s review we focus on an area of ceria defect chemistry which has received comparatively little attent

293 Changing ocean chemistries will alter the iron bioavailability when a d

294 We point out the chemistries with low or extremely low established fade r

295 Host-guest solution chemistry with a wide range of organic hosts is an impor

296 The merging of click chemistry with discrete photochemical processes has led

297 to this dynamic interface, we combined Click chemistry with pulsed stable isotope labelling of amino

298 combining stable isotope labeling and click chemistry with subsequent mass spectrometry analysis.

299 nvestigation into 2-cyanobenzothiazole (CBT) chemistry within a protein nanoreactor.

300 are ubiquitous functional groups in organic chemistry, yet despite their obvious appeal as surface-b