ライフサイエンスコーパス: chemo-

1 OS at 3 years: 58% vs 70% (5-FU) vs 84% (no-chemo)].

2 aged patients were rituximab/chemotherapy (R-chemo; 28%), XRT (27%), observation (17%), systemic ther

3 y of stimuli, including thermal, mechanical, chemo, and photo.

4 inacolato)diboron, and imines allows regio-, chemo-, and diastereoselective assembly of branched alph

5 nzophospholes become accessible in a regio-, chemo-, and diastereoselective way.

6 xcellent yields as well as with high regio-, chemo-, and diastereoselectivity as a result of the comb

7 method is broadly applicable, highly regio-, chemo-, and enantioselective, and provides direct access

8 The reduction reaction is rapid, chemo-, and enantioselective, occurs under mild conditio

9 Mouse lemurs are basal primates that rely on chemo- and acoustic signalling for social interactions i

10 the vagus and activation of cardiopulmonary, chemo- and baroreceptor reflexes.

11 ar to function not only as a medium for both chemo- and bio-catalysis, but as a reservoir for substra

12 ciency gains that innovative developments in chemo- and biocatalysis can have on the synthesis of pha

13 lights the importance of selecting from both chemo- and biocatalysts for optimal results.

14 ence, and time course; radiosensitization by chemo- and biologic therapy; and the addition of novel,

15 rganic molecules and proteins with excellent chemo- and bioselectivity.

16 ritical chemical and biological information (chemo- and biosensors) that can be digitized and made av

17 ic devices like field effect transistors, as chemo- and biosensors, catalysts, or in energy material

18 on of an advanced enone intermediate and the chemo- and diastereoselective addition of trimethylalumi

19 Alkoxyallylsiletanes are capable of highly chemo- and diastereoselective carbonyl allylsilylations.

20 via radical intermediates under mild regio-, chemo- and diastereoselective conditions that are fully

21 ute relies on the development of a catalytic chemo- and diastereoselective hydrosilylation.

22 A highly chemo- and diastereoselective protocol toward amino-subs

23 eoselective modified Claisen condensation, a chemo- and diastereoselective reduction of a beta-keto e

24 appropriate oxocarbenium cation and a highly chemo- and diastereoselective ring-closing metathesis pr

25 This highly chemo- and diastereoselective transformation underscores

26 s produced with high efficiency and complete chemo- and diastereoselectivity by diversification of an

27 derivatives in excellent yields, with total chemo- and diastereoselectivity.

28 ds some small-molecule SGLT2 inhibitors by a chemo- and diastereospecific palladium-catalyzed arylati

29 A highly reactive, chemo- and enantioselective addition of diphenylphosphin

30 d solvent combinations crucial for achieving chemo- and enantioselective C-alkylation of electronical

31 This paper describes a highly chemo- and enantioselective epoxidation of conjugated ci

32 g efficient O-O cleavage and creating highly chemo- and enantioselective epoxidizing species which pr

33 mild step and atom-economical nonepimerizing chemo- and enantioselective N-alkylating procedure has b

34 the capability of our catalyst to perform a chemo- and enantioselective process while using simple a

35 Reported herein are chemo- and enantioselective silver-catalyzed aminations

36 t high C horizontal lineO/C horizontal lineC chemo- and enantioselectivities.

37 ituents, the reactions occur with remarkable chemo- and enantioselectivities; the competing Curtius-t

38 This system may provide both chemo- and enantioselectivity toward multiple analytes s

39 dating a broad range of substrates with high chemo- and enantioselectivity.

40 earing a variety of substituents in terms of chemo- and enantioselectivity.

41 broadly applicable to alternative systems of chemo- and haptotaxis such as cells migrating along grad

42 nt susceptibilities to otherwise ineffective chemo- and immunotherapies through SASP-dependent effect

43 larity, immunosuppression, and resistance to chemo- and immunotherapies.

44 cal trials exploring various combinations of chemo- and immunotherapy rely on serial biopsy to provid

45 t to treatment of hematologic neoplasms with chemo- and immunotherapy.

46 er, although anatomically closely connected, chemo- and mechano-sensory neurons are functionally segr

47 The vagus nerve supplies low-threshold chemo- and mechanosensitive afferents to the mucosa of t

48 Furthermore, distinct chemo- and mechanosensory cells exhibit specific recepto

49 ed with diverse sensory bristles of both the chemo- and mechanosensory systems.

50 at selective silencing of this pathway using chemo- and optogenetic approaches impaired fear memory r

51 blockers with unique properties; including, chemo- and optogenetic control of channel activity, and

52 le to domains linked by alpha-helices and to chemo- and photosensors.

53 s sulfide oxidation during sulfide-dependent chemo- and phototrophic growth in bacteria.

54 ded with ample scope and excellent levels of chemo- and position selectivities within an organometall

55 common debilitating toxicity associated with chemo- and radiation therapies, is a significant unmet c

56 th stage IB-IVA cervical cancer treated with chemo- and radiation therapy in 2009-2013.

57 previously unknown role for normal cells in chemo- and radiation therapy of cancer.

58 ocally advanced cervical cancer treated with chemo- and radiation therapy.

59 hese changes could promote responses to both chemo- and radiation therapy.

60 vical cancers that makes tumors resistant to chemo- and radiation therapy.

61 kappaB is also crucial to oncogenesis and to chemo- and radio-resistance in cancer.

62 Hypoxia confers chemo- and radio-resistance, and alongside PDGF, is impl

63 gulation, cell proliferation, DNA repair and chemo- and radio-resistance.

64 on of C53 may represent a novel approach for chemo- and radio-sensitization of cancer cells.

65 leads in part to resistance to some existing chemo- and radiological treatments.

66 IL-1 has putative chemo- and radioprotective properties, but its effects o

67 tumor cells, activation of NRF2 may lead to chemo- and radioresistance and thus affect patient outco

68 and may become a prerequisite for overcoming chemo- and radioresistance using radiosensitizing drugs

69 thermore, CSCs are believed to contribute to chemo- and radioresistance.

70 y associates with poor patient prognosis and chemo- and radioresistance.

71 gh elevated PUMA expression elicits profound chemo- and radiosensitization in cancer cells, inhibitio

72 ered as therapeutic targets with a promising chemo- and radiosensitizing potential.

73 food intake and the toxicity and efficacy of chemo- and radiotherapeutic agents.

74 ne response is key to the success of various chemo- and radiotherapeutic regimens.

75 Chemical and physical treatments such as chemo- and radiotherapies have also made a major contrib

76 sed invasive capacity and resistance to both chemo- and radiotherapies, and therefore represent an at

77 ion may enhance the effectiveness of current chemo- and radiotherapies.

78 o increase the efficacy of such compounds as chemo- and radiotherapies.

79 in tumor cells or sensitize these tumors for chemo- and radiotherapies.

80 It is widely known that surgery, chemo- and radiotherapy also inhibit normal cells growth

81 nal cell carcinoma (RCC) is polyresistant to chemo- and radiotherapy and biologicals, including TNF-r

82 ed increased clonogenicity and resistance to chemo- and radiotherapy as compared with their tagBFP(Ne

83 drug inhibition of NHEJ in combination with chemo- and radiotherapy has proved successful, making th

84 Intrinsic or acquired resistance to chemo- and radiotherapy is common and contributes to a h

85 anced DNA2-overexpressing cancers to current chemo- and radiotherapy regimens.

86 Most modern chemo- and radiotherapy treatments of human cancers use

87 l invasion, metastatic spread, resistance to chemo- and radiotherapy, and is an independent, negative

88 is not only resistant to androgen ablation, chemo- and radiotherapy, but also highly metastatic.

89 ancy characterized by frequent resistance to chemo- and radiotherapy, poor outcome, and limited thera

90 tic mechanisms render GBM cells resistant to chemo- and radiotherapy, we hypothesized that these anti

91 Tumor hypoxia contributes resistance to chemo- and radiotherapy, while oxygenated tumors are sen

92 h poor patient survival and poor response to chemo- and radiotherapy.

93 ve tumors that are resistant to conventional chemo- and radiotherapy.

94 on in HNSCC and renders cancers resistant to chemo- and radiotherapy.

95 growth in metastatic sites and responses to chemo- and radiotherapy.

96 as well as its role in sensitizing cells to chemo- and radiotherapy.

97 s as well as to their limited sensitivity to chemo- and radiotherapy.

98 by excellent efficiency as well as complete chemo- and regio-selectivity in both simple and complex

99 These results could be explained through a chemo- and regioselective 5-exo aminocyclization to the

100 nt step, the enyne-urea derivative undergoes chemo- and regioselective 6-endo cyclization to afford O

101 ns furnished 3,6-dihydro-2H-pyrans through a chemo- and regioselective 6-endo cycloetherification.

102 he electron-deficient alkene and undergoes a chemo- and regioselective [3 + 2] cycloaddition.

103 ochrome P450 enzyme was employed to effect a chemo- and regioselective allylic C-H oxidation in the p

104 A unique chemo- and regioselective alpha- and gamma-arylation of

105 The reaction is highly chemo- and regioselective and offers a new approach to t

106 This strategy has been applied to the chemo- and regioselective assembly of indanone arrays an

107 A chemo- and regioselective auxiliary-mediated peptide lig

108 minotetrazole, as a directing group, for the chemo- and regioselective C-H halogenation of arenes.

109 ohydrate moiety and the advantages of highly chemo- and regioselective click chemistry, such as mild

110 A chemo- and regioselective copper-catalyzed cross-couplin

111 [reaction, structure: see text] A chemo- and regioselective copper-catalyzed cross-couplin

112 A new chemo- and regioselective coupling protocol between 3-ar

113 inocyclopentadienones have been subjected to chemo- and regioselective cycloadditions with dienophile

114 a single compound, beta-caryophyllene, via a chemo- and regioselective ene reaction.

115 + 1 cycloetherification pathways in a highly chemo- and regioselective fashion to obtain skeletally a

116 and alkyne partners in good yield, and in a chemo- and regioselective fashion, despite the significa

117 es can be added across an alkene in a highly chemo- and regioselective fashion.

118 A new concept of highly chemo- and regioselective formation of the benzene ring

119 ht-step synthetic strategy involves a highly chemo- and regioselective gold-catalyzed cycloisomerizat

120 We report the chemo- and regioselective hydrogenolysis of the C-O bond

121 A rhodium-catalyzed chemo- and regioselective intermolecular decarboxylative

122 A chemo- and regioselective intermolecular sp(3) C-H and s

123 A novel simple, mild chemo- and regioselective method has been developed for

124 ne directing-group-assisted Ru(II)-catalyzed chemo- and regioselective ortho-C-H alkenylation of aren

125 An efficient Cu-catalyzed chemo- and regioselective ortho-nitration of N,1-diaryl-

126 An efficient Cu-catalyzed chemo- and regioselective ortho-nitration of N,1-diaryl-

127 -((2,6-diisopropylphenyl)-imino)-2-pentene], chemo- and regioselective polymerizations of lactide (LA

128 rated a N-hydroxyphthalimide (NHPI)-mediated chemo- and regioselective radical cyclization of yne-die

129 zines were prepared from a sequence of three chemo- and regioselective reactions combining amination

130 essential, as it guides the reactivity to a chemo- and regioselective substrate desaturation from th

131 iodides has been developed, enabling highly chemo- and regioselective synthesis of unsymmetrical dia

132 The reaction is both chemo- and regioselective, as only 4,6-disubstituted 2-a

133 The reaction is chemo- and regioselective, displaying wide substrate sco

134 are few catalytic aerobic examples that are chemo- and regioselective.

135 that the ring closure of these diols is both chemo- and regioselective.

136 The reaction proceeds chemo- and regioselectively in an atom-economic way, gen

137 The chemo- and regioselectivities are controlled by the enha

138 could be easily prepared with high levels of chemo- and regioselectivities by hydrofluorination of re

139 Excellent chemo- and regioselectivities to five-membered cyclic ur

140 a highly enantioselective fashion with good chemo- and regioselectivities.

141 including substituent effects on reactivity, chemo- and regioselectivity and the effects of oxidant i

142 This process displays exceptional chemo- and regioselectivity as well as high diastereosel

143 Many strategies developed to date lack chemo- and regioselectivity as well as result in non-nat

144 ne-pot method provided 23 examples with high chemo- and regioselectivity at yields up to 96%.

145 Chemo- and regioselectivity depend on both linker elonga

146 hyl-1-piperidinyl-N-oxyl) displays excellent chemo- and regioselectivity for the oxidation of less hi

147 The excellent chemo- and regioselectivity highlights the synthetic pot

148 yrroles has been achieved through switchable chemo- and regioselectivity in the metal-catalyzed heter

149 The high chemo- and regioselectivity observed for these reactions

150 The chemo- and regioselectivity of the initial attack in ski

151 The chemo- and regioselectivity of the reaction may be tuned

152 Achieving chemo- and regioselectivity simultaneously is challengin

153 lation of vinyl 2- and 3-carboxyarenes, with chemo- and regioselectivity up to 100%.

154 (viii) high chemical yields, (ix) excellent chemo- and regioselectivity, (x) short reaction time, (x

155 To account for the chemo- and regioselectivity, the initial formation of th

156 eactions require exquisite control over both chemo- and regioselectivity, under ambient, aqueous cond

157 formed in moderate to good yields with high chemo- and regioselectivity.

158 ross-coupling of different phenols with high chemo- and regioselectivity.

159 method in moderate to good yields with high chemo- and regioselectivity.

160 wing the transformation to proceed with high chemo- and regioselectivity.

161 The methods are mild, proceeding with high chemo- and regioselectivity.

162 with each other in good yield and excellent chemo- and regioselectivity.

163 rapidly affording acrylamides with excellent chemo- and regioselectivity.

164 While 1 catalyzes the rapid chemo- and shape-selective oxidation of thiols to disulf

165 l-containing natural products involving both chemo- and site-selective ("chemosite" selective) and si

166 Chemo- and site-selectivity was studied with a diverse l

167 re few in number, they demonstrate exquisite chemo- and stereo-selectivity.

168 rward access to ketopyranosides with a large chemo- and stereodiversity at position 2.

169 An efficient and chemo- and stereoselective access to various tri- and te

170 Transition-metal-free chemo- and stereoselective addition of 5-aminoindole (1a

171 ds by S-alkylation has been developed, using chemo- and stereoselective alkylation of a C2-thiolated

172 these supported Cu nanoparticles into highly chemo- and stereoselective catalysts for the preparation

173 development of new methodologies that enable chemo- and stereoselective construction of fluorinated s

174 hly refined protecting group strategy, and a chemo- and stereoselective epoxidation at C(18,19).

175 carbon introduced in the Prins-pinacol step; chemo- and stereoselective hydroxyl-directed epoxidation

176 Other key transformations include chemo- and stereoselective hydroxyl-directed epoxidation

177 n of tryptamine with 2,3-pentanedione; (b) a chemo- and stereoselective intramolecular oxidative cycl

178 d secondary 3 beta-alcohol 11 and the highly chemo- and stereoselective isomerization of dieneoxide e

179 carbinol and the cyclopropane determine both chemo- and stereoselective outcomes.

180 tereoselective alkylation of (+)-nopinone, a chemo- and stereoselective reduction of an oxime to an a

181 A method has been developed for the chemo- and stereoselective Suzuki-Miyaura cross-coupling

182 nd moisture tolerant, high-yielding, totally chemo- and stereoselective.

183 ith excellent functional group tolerance and chemo- and stereoselectivities.

184 use of 2-deoxy-d-glucose resulted in reduced chemo- and stereoselectivity and the formation of four p

185 The redox-economy, chemo- and stereoselectivity embodied by this new class

186 formation, which displayed good to excellent chemo- and stereoselectivity for a broad array of substr

187 ity and low reactivity, controlling both the chemo- and stereoselectivity of such processes constitut

188 roducts in fewer steps and with the pristine chemo- and stereoselectivity that is a hallmark of bioca

189 zed pyrrolidines and dihydrofurans with high chemo- and stereoselectivity.

190 hiazolines (oxidized to thiazoles) with high chemo- and stereoselectivity.

191 substrates via simultaneous sensing of both chemo- and stereoselectivity; and to create generalized

192 bits apoptosis induced by a wide spectrum of chemo- and targeted therapies upstream of Bcl2-associate

193 the sensitivity of breast cancer patients to chemo- and targeted therapies.

194 re accurately recapitulate tumor response to chemo- and targeted therapies.

195 hrough the application of specific targeted, chemo- and/or immune-therapies.

196 ts with abnormal posture who did not receive chemo- and/or radiation therapy included the fastigial a

197 are exposed to known mutagens in the form of chemo- and/or radiotherapy for cancer in the States.

198 ly strongly resistant to currently available chemo- and/or radiotherapy regimens, including targeted

199 es were acquired 3 weeks after initiation of chemo- and/or radiotherapy.

200 Here we describe the topography, the chemo-, cyto-, and myeloarchitectonics, and the ultrastr

201 A highly chemo-, diastereo- and enantioselective catalytic method

202 ha-keto ester reduction, excellent levels of chemo-, diastereo-, and enantiocontrol can be realized i

203 um ion, chlorolactonization suffers from low chemo-, diastereo-, and enantioselectivities.

204 substituted beta-amino ynones with excellent chemo-, diastereo-, and enantioselectivity.

205 adjuvant chemotherapy, intraoperative heated chemo, female sex, and length of stay shorter than 14 da

206 nverted to unsaturated diboronates with high chemo- (>98% reaction of alkyne; <2% at alkene) and enan

207 y: HR, 0.59; 95% CI, 0.42-0.84; surgery plus chemo: HR, 0.19; 95% CI, 0.07-0.46).

208 A ligandomes of patients undergoing standard chemo-/immunotherapy.

209 ectal cancer response to preoperative RT +/- chemo, only one patient has died as a consequence of can

210 No efficacious chemo- or immunotherapies have been identified for crypt

211 ng tumor progression and after recovery from chemo- or immunotherapy.

212 RC(POMC) neurons, rapidly cause satiety when chemo- or optogenetically manipulated.

213 ug target whose inhibitors have potential as chemo- or radiation sensitizers or as monotherapy in tum

214 enal cell carcinoma (RCC) responds poorly to chemo- or radiation therapy but appears to respond to sy

215 ensitizing agents to act in conjunction with chemo- or radiation therapy of cancer cells.

216 impaired in those patients who had received chemo- or radiation therapy.

217 BRT), and tumor ablation (with transarterial chemo- or radio-embolization).

218 n the pre-clinical setting as a strategy for chemo- or radio-potentiation.

219 to resection, local ablation, transarterial chemo- or radioembolization, or radiation therapy from J

220 to resection, local ablation, transarterial chemo- or radioembolization, or radiation therapy, from

221 C cancer stem cell (CSC) characteristics and chemo- or radioresistance concomitantly through Rac1 act

222 s closely associated with poor prognosis and chemo- or radiotherapeutic resistance.

223 or can enhance target cell susceptibility to chemo- or radiotherapeutics by effecting the modulation

224 intervention, especially in combination with chemo- or radiotherapies.

225 TRAIL treatment in combination with chemo- or radiotherapy enhances TRAIL sensitivity or rev

226 eting molecules in combination with adjuvant chemo- or radiotherapy following surgical resection has

227 rior chemo- or radiotherapy, timing of prior chemo- or radiotherapy in relation to RAIT, type and num

228 tes to tumorigenesis, tumor progression, and chemo- or radiotherapy resistance.

229 ailure through their intrinsic resistance to chemo- or radiotherapy, thus representing a substantial

230 , bone or marrow (or both) metastases, prior chemo- or radiotherapy, timing of prior chemo- or radiot

231 Using an experimental design free of chemo- or radiotherapy, we found CD40 activation with ag

232 uman tumors and contributes to an aggressive chemo- or radiotherapy-resistant phenotype, therefore pr

233 umor growth, pathogenesis, and resistance to chemo- or radiotherapy.

234 53, as well as for the response of tumors to chemo- or radiotherapy.

235 Accurate prediction of chemo- or targeted therapy responses for patients with s

236 DFS at 3 years: 14% vs 38% (5-FU) vs 45% (no-chemo), OS at 3 years: 58% vs 70% (5-FU) vs 84% (no-chem

237 The combinational chemo- photodynamic therapy heavily suppresses tumor gro

238 current rectal carcinoma (after neoadjuvant (chemo)-radiation, with or without intraoperative radioth

239 n, and metastasis and lowers the efficacy of chemo-, radio-, and immunotherapies.

240 geting fast-proliferating tumor cells during chemo-, radio-, and immunotherapy.

241 gy, multi-targeting and multi-drug strategy, chemo-/radio-/photodynamic-/ultrasound-/thermo-combined

242 is a melanoma antigen overexpressed in most chemo-/radiotherapeutic stress-resistant tumor clones, a

243 nts with a clinical complete response after (chemo) radiotherapy who undergo a W&W policy will experi

244 nts with a clinical complete response after (chemo) radiotherapy.

245 s stages: initial diagnosis, during therapy (chemo-, radiotherapy, surgery), and in the post-therapy

246 allenes poses several challenges in terms of chemo-, regio- and enantio-selectivity.

247 mining both the catalytic efficiency and the chemo-, regio- and enantioselectivity of enzymes, thus e

248 nsformation of synthetic chemicals with high chemo-, regio- and enantioselectivity.

249 cess to these privileged scaffolds with high chemo-, regio- and enantioselectivity.

250 An impressive variety of chemo-, regio- and stereoselective carbon-carbon and car

251 ieving high rate-enhancements with excellent chemo-, regio- and stereoselectivities.

252 lkyne starting materials with high levels of chemo-, regio- and stereoselectivity.

253 umerous transition-metal complexes to effect chemo-, regio-, and diastereoselective NT.

254 Various chemo-, regio-, and diastereoselective transformations o

255 Excellent chemo-, regio-, and diastereoselectivities are observed

256 benzoxa[3.2.1]octane scaffold with excellent chemo-, regio-, and diastereoselectivity under exception

257 under surprisingly mild conditions with high chemo-, regio-, and diastereoselectivity, while tolerati

258 nes under mild conditions and with excellent chemo-, regio-, and diastereoselectivity.

259 Herein we describe a highly chemo-, regio-, and enantioselective bromochlorination r

260 s has been enabled by our recently developed chemo-, regio-, and enantioselective dihalogenation reac

261 (DAAA) of allyl enol carbonates as a highly chemo-, regio-, and enantioselective process for the syn

262 amination of C(sp(3))-H bonds with excellent chemo-, regio-, and enantioselectivity, using a readily

263 ing heterocycle functionalizations with high chemo-, regio-, and stereocontrol.

264 go facile Nazarov cyclization with excellent chemo-, regio-, and stereocontrol.

265 n alternative approach is to employ a highly chemo-, regio-, and stereocontrolled allene oxidation th

266 This domino process proved to be chemo-, regio-, and stereoselective and allows the forma

267 ique (E)-chlorovinyl sulfate is created by a chemo-, regio-, and stereoselective E2 elimination of HC

268 borylation protocol proceeds in a remarkably chemo-, regio-, and stereoselective fashion to afford 1,

269 The development of the first chemo-, regio-, and stereoselective hetero-[6+4] and -[6

270 the C7 tertiary hydroxyl center of 1 and 8; chemo-, regio-, and stereoselective intramolecular oxyme

271 A chemo-, regio-, and stereoselective iron-catalyzed 1,4-h

272 ze the aziridination of 2,4-diene-1-ols in a chemo-, regio-, and stereoselective manner to give vinyl

273 -rich hetero-6pai-component that reacts in a chemo-, regio-, and stereoselective manner with electron

274 Transition-metal-free chemo-, regio-, and stereoselective synthesis of (Z) and

275 One-pot chemo-, regio-, and stereoselective synthesis of series

276 e place under mild conditions and are highly chemo-, regio-, and stereoselective with up to 99% Z-sel

277 ed cascade reaction proceeded with exclusive chemo-, regio-, and stereoselectivities and showed a wid

278 The chemo-, regio-, and stereoselectivities of multicomponen

279 Factors capable of exerting control over the chemo-, regio-, and stereoselectivities of the attack of

280 These effects are manifested by the unusual chemo-, regio-, and stereoselectivities shown by the sup

281 Good chemo-, regio-, and stereoselectivities were observed wi

282 The factors controlling chemo-, regio-, and stereoselectivity in a cascade of re

283 The development, synthetic utility, and chemo-, regio-, and stereoselectivity of this imine chap

284 Many of these enzymes exhibit fascinating chemo-, regio-, and stereoselectivity, in spite of emplo

285 s and aldimines as nucleophiles to engage in chemo-, regio-, diastereo- and enantioselective C-C bond

286 uction of amino alcohols with high levels of chemo-, regio-, diastereo- and enantioselectivity.

287 ariably formed in good yields, with rigorous chemo-, regio-, diastereo-, and enantiocontrol.

288 nconventional nucleophiles to mediate highly chemo-, regio-, diastereo-, and enantioselective C-C bon

289 le substituted [3]dendralenes undergo highly chemo-, regio-, diastereo-, and enantioselective organoc

290 ers, with one being quaternary, in excellent chemo-, regio-, diastereo-, and enantioselectivities in

291 cipated in the transformation with excellent chemo-, regio-, diastereo-, and enantioselectivtities, l

292 uring substrate oxidation; and modulation of chemo-, regio-, or stereoselectivity of a reaction.

293 rapidly, with exquisite regio, and sometimes chemo, selectivity.

294 l-product settings with predictable and high chemo-, site-, and even diastereoselectivities.

295 The impeccable control over chemo-, site-, and stereoselectivity possible in enzymat

296 s under ambient conditions with near-perfect chemo-, stereo- and isotopic selectivity.

297 a variety of reactions with a high degree of chemo-, stereo- and regioselectivity in most of the reac

298 stringent conditions required by Nature: the chemo-, stereo-, and regioselectivity of the desaturatio

299 in animals, protists, and fungi are primary chemo-, thermo-, or mechanosensors.

300 tments using DNA-targeted therapy (radiation/chemo) together with antiangiogenic therapies reduced GB