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1 py (surgery with chemotherapy, radiation, or chemoradiation).
2 inoma benefit significantly from neoadjuvant chemoradiation.
3 en in the subgroup that received neoadjuvant chemoradiation.
4 o demonstrate survival benefit from adjuvant chemoradiation.
5 t consisting of transurethral resection with chemoradiation.
6 jected to curable treatment with surgery and chemoradiation.
7 n patients with NSCLC treated by concomitant chemoradiation.
8 ade 3-4 haematological adverse events during chemoradiation.
9 ad total mesorectal excision 6-8 weeks after chemoradiation.
10 d disease, which include chemotherapy and/or chemoradiation.
11 ncer when given as maintenance therapy after chemoradiation.
12 s were obtained before and after neoadjuvant chemoradiation.
13 no hypoxia response within the first 2 wk of chemoradiation.
14 eal squamous cell carcinoma (ESCC) receiving chemoradiation.
15 duction is related to clinical outcome after chemoradiation.
16 ents (total, 220) undergoing chemotherapy or chemoradiation.
17 Subsequently, patients received 5-FU based chemoradiation.
18 C receiving SOC neoadjuvant chemotherapy and chemoradiation.
19 after cediranib treatment, unlike that after chemoradiation.
20 ancer patients with a pCR after preoperative chemoradiation.
21 r patients with a pCR following preoperative chemoradiation.
22 onse 3 mo after the completion of concurrent chemoradiation.
23 prior to definitive radiation or concurrent chemoradiation.
24 misonidazole PET at weeks 0, 2, and 5 during chemoradiation.
25 g interferon-alpha with 5-fluorouracil-based chemoradiation.
26 patients; 79 patients (88%) completed chemo-chemoradiation.
27 ncepts for biology-driven personalization of chemoradiation.
28 aluation of patients for esophagectomy after chemoradiation.
29 problems with re-staging rectal cancer after chemoradiation.
30 ioma patients at diagnosis, before and after chemoradiation.
31 in those demonstrating objective response to chemoradiation.
32 18 months among patients given neo-adjuvant chemoradiation.
33 of cisplatin administered during concurrent chemoradiation.
34 e of the situation in vivo during concurrent chemoradiation.
35 ory comorbidity, tumor site, and neoadjuvant chemoradiation.
36 concomitant with induction chemotherapy and chemoradiation.
37 or T1b, as an alternative to no treatment or chemoradiation.
38 in glioblastoma recurrence after therapeutic chemoradiation.
39 as significantly associated with neoadjuvant chemoradiation.
40 ical cancer patients treated with definitive chemoradiation.
41 radiotherapy, and 53% prefer 5 to 6 weeks of chemoradiation.
42 progress rapidly and do not respond well to chemoradiation.
43 d the confounding impact of radiotherapy and chemoradiation.
44 with rectal cancer treated with preoperative chemoradiation.
45 nificant increase in the use of preoperative chemoradiation (1% versus 42%, P < 0.001) in the histori
46 8.6 months; endoscopic therapy, 77.7 months; chemoradiation, 17.3 months; no treatment, 8.2 months; P
47 histology (69% vs. 86%); use of neoadjuvant chemoradiation (28% vs. 52%); mean blood loss (677 vs. 3
49 d to 5 weeks preoperative capecitabine-based chemoradiation (45-50.4 Gy) followed by six cycles of ad
50 ll or adenocarcinoma and planned neoadjuvant chemoradiation (5- fluorouracil, cisplatin, 40Gy) follow
51 py, 51% v 71%, respectively; P = .038; after chemoradiation, 75% v 93%, respectively; P = .028) and O
52 n the selection of patients for preoperative chemoradiation, a strategy proven to improve outcomes in
53 without concurrent chemotherapy, or primary chemoradiation according to initial nodal disease burden
56 ance; Phase III Intergroup Trial of Adjuvant Chemoradiation After Resection of Gastric or Gastroesoph
57 carcinoma, previously randomized to adjuvant chemoradiation after surgery or surgery alone, to measur
58 systemic chemotherapy alone (n = 38; 6.5%), chemoradiation alone (n = 261; 44.8%), or both (n = 284;
60 parable survival has been demonstrated using chemoradiation alone, leading to the hypothesis that sur
65 erapy increased from 12.7% to 33.6%, whereas chemoradiation and esophagectomy decreased, P < 0.01.
66 h esophageal cancer treated with neoadjuvant chemoradiation and esophagectomy in the National Cancer
68 adjuvant chemotherapy (AC) after neoadjuvant chemoradiation and esophagectomy is associated with impr
70 peutic options will increase the efficacy of chemoradiation and improved the survival of these patien
71 ed by a significant response to preoperative chemoradiation and intersphincteric resection, without c
73 ellent single-center outcomes of neoadjuvant chemoradiation and liver transplantation for unresectabl
74 es and outcomes in HNSCC patients undergoing chemoradiation and may help to devise novel concepts for
75 rentiated tumors evidencing less response to chemoradiation and more likely to require extended resec
76 fter, a novel protocol combining neoadjuvant chemoradiation and orthotopic liver transplantation was
77 who received preoperative gemcitabine-based chemoradiation and pancreaticoduodenectomy (PD) for stag
78 n anoscopy-guided ablation) and anal cancer (chemoradiation and possibly intensity-modulated radiatio
79 aliplatin to preoperative capecitabine-based chemoradiation and postoperative adjuvant chemotherapy i
80 aliplatin to preoperative capecitabine-based chemoradiation and postoperative capecitabine improves d
81 comparing induction chemotherapy followed by chemoradiation and surgery in patients with locally adva
82 ss whether adding cycles of mFOLFOX6 between chemoradiation and surgery increased the proportion of p
84 fic resistances to treatment with concurrent chemoradiation and temozolomide, and that the model can
85 ed with neoadjuvant chemotherapy followed by chemoradiation and then an operation or an operation fir
86 from the anal verge, treated by preoperative chemoradiation and total mesorectal excision from 1998 t
88 t restaging 4 to 6 weeks after completion of chemoradiation and, in the absence of disease progressio
89 nse at 26 weeks and acute toxic effects (for chemoradiation), and progression-free survival (for main
90 compared endoscopic therapy, esophagectomy, chemoradiation, and no treatment; and performed a subgro
93 native chemotherapy regimens and neoadjuvant chemoradiation are being investigated to improve outcome
94 y strategies incorporating radiation or even chemoradiation are frequently considered in some cases.
96 herapy alone, firmly establishing concurrent chemoradiation as the standard of care in locally advanc
97 copic biopsies can predict minor response to chemoradiation, as a basis for individualized therapy of
101 disease (MRD; enhancing tumour <2 cm(2) post-chemoradiation by central review), analysed by modified
105 in Carcinoma of the Anal Canal], concurrent chemoradiation (CCR) with fluorouracil (FU) plus mitomyc
107 ylation inhibitors, angiogenesis inhibitors, chemoradiation, complexes with neoantigen-targeted monoc
110 as divided into five phases: preirradiation, chemoradiation, consolidation, maintenance, and continua
111 The Timing of Rectal Cancer Response to Chemoradiation Consortium designed a prospective, multic
112 The identification of patients with a pCR to chemoradiation could potentially spare those patients th
113 rates after sphincter-preserving definitive chemoradiation (CRT) and is typically associated with an
114 s undergoing outpatient radiotherapy (RT) or chemoradiation (CRT) frequently require acute care (emer
118 adiation twice a day (FCT) is an established chemoradiation (CRT) regimen for selective bladder-spari
119 shown resistance to conventional concurrent chemoradiation (CRT) therapy and carries a relatively po
120 TNT, or systemic chemotherapy followed by chemoradiation (CRT), addresses both occult metastases a
121 egional failure (LRF) rates after definitive chemoradiation (CRT), associated with anogenital human p
124 inical and radiologic imaging response after chemoradiation do not require elective neck dissection.
125 l-based study, the addition of postoperative chemoradiation (either sequentially or concomitantly) af
129 local excision alone for very early tumors, chemoradiation followed by either local excision of a sm
131 stal rectal cancer treated with preoperative chemoradiation followed by low anterior resection (LAR)/
133 ded into 2 treatment groups: (1) neoadjuvant chemoradiation followed by surgery and (2) surgery alone
134 identified, of whom 539 received neoadjuvant chemoradiation followed by surgery and 770 received surg
135 The 3-year OS was better for neoadjuvant chemoradiation followed by surgery compared with surgery
136 NCT00445861), which investigated neoadjuvant chemoradiation followed by surgery in patients with esop
139 omplete response (pCR) following neoadjuvant chemoradiation for advanced pancreatic ductal adenocarci
141 Patients without response to neoadjuvant chemoradiation for esophageal cancer have no prognostic
143 : In total, 49 patients receiving definitive chemoradiation for locally advanced HNSCCs underwent pre
144 review of 27 patients undergoing concurrent chemoradiation for locally advanced laryngeal cancers (8
145 review of 33 patients undergoing concurrent chemoradiation for locally advanced oropharyngeal cancer
146 nse with (18)F-FDG PET after curative-intent chemoradiation for non-small cell lung cancer (NSCLC) is
149 and the addition of cetuximab to concurrent chemoradiation for patients with inoperable stage III no
151 lusion Although the addition of cetuximab to chemoradiation for SCCAC was associated with lower LRF r
153 d to improve the reporting of RCTs examining chemoradiation for treatment of patients with squamous c
154 ndomised controlled trials (RCTs) of radical chemoradiation for treatment of squamous cell carcinoma
155 ria for an incomplete response to definitive chemoradiation for which salvage neck dissection would b
156 ne and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy
161 s, here we report that CC CSCs, which resist chemoradiation, have higher SUMO activating enzyme (E1)
162 er for cN+ patients who received neoadjuvant chemoradiation (hazard ratio, 0.52; 95% CI, 0.42-0.66; P
163 95% CI: 1.15-2.66, P = 0.009), and adjuvant chemoradiation (HR: 0.57, 95% CI: 0.42-0.78, P < 0.0001)
164 oved survival [hazard ratio (HR): 0.85], and chemoradiation (HR: 1.79) and no treatment (HR: 3.57) wi
165 hemotherapy or postoperative chemotherapy or chemoradiation improves outcomes relative to surgery alo
166 hether replacing mitomycin with cisplatin in chemoradiation improves response, and whether maintenanc
167 was undertaken to determine whether adjuvant chemoradiation improves survival compared with surgery a
169 mly assigned patients with progression after chemoradiation in a 2:1 ratio to receive lomustine plus
171 ith resistance to cytotoxic chemotherapy and chemoradiation in an understudied phenomenon known as hy
172 table perihilar CCA treated with neoadjuvant chemoradiation in anticipation for transplantation betwe
173 the ability of PDOs to predict responses to chemoradiation in cancer patients remains an open questi
179 tion chemotherapy to concomitant neoadjuvant chemoradiation in locally advanced rectal cancer could i
180 s article reviews data supporting the use of chemoradiation in NMIBC and discusses emerging biomarker
182 nstability (MSI) and response to neoadjuvant chemoradiation in rectal cancer is not well understood.
183 ied X-rays improves the efficacy of standard chemoradiation in resistant and aggressive head and neck
184 A clinical trial investigating the role for chemoradiation in T1 disease that has recurred is underw
185 There is an increasing use of neoadjuvant chemoradiation in this group of patients, especially for
187 e induction of adult stem cells could repair chemoradiation-induced tissue injury and prolong overall
189 , and predicted response to chemotherapy and chemoradiation irrespective of anatomic subtype (P < 0.0
191 reas liver transplantation after neoadjuvant chemoradiation is an option for a subset of patients wit
192 done little to improve survival and combined chemoradiation is associated with significant adverse ef
196 nts with a complete response to preoperative chemoradiation is frequently reported as a marker of tre
197 Further optimisation of present standard chemoradiation is needed in patients with locally advanc
198 An immunotherapy approach integrated with chemoradiation is safe and demonstrates an overall survi
200 agement in patients with rectal cancer after chemoradiation is the inability to identify a pCR preope
201 k areas (esophagus/rectum) where neoadjuvant chemoradiation is used, the incidence of anastomotic lea
202 ive chemoradiation or postoperative adjuvant chemoradiation is widely practiced in major centers.
203 systemic induction chemotherapy followed by chemoradiation, is an optimal preoperative sequencing st
204 The current standard of care-resection and chemoradiation-is limited in part due to the genetic het
205 0, OR: 2.2) CONCLUSIONS:: After preoperative chemoradiation, long-term outcomes of esophageal carcino
207 All patients were treated with definitive chemoradiation (median dose 50.4 Gy) followed by resecti
208 66), including chemotherapy alone (n = 354), chemoradiation (n = 190, including 99 patients who under
209 ectal cancer (LARC) treated with neoadjuvant chemoradiation (NACR) enrolled in a phase III clinical t
211 te clinical response (cCR) after neoadjuvant chemoradiation (nCRT) managed nonoperatively after each
213 The impact of adjuvant chemotherapy and chemoradiation on survival has been more clearly defined
214 urrently, there is insufficient evidence for chemoradiation only, or nonoperative management (NOM), t
216 operable stage II or III NSCLC, treated with chemoradiation or with radiotherapy alone, were extracte
218 ite improvements in survival with aggressive chemoradiation, outcomes for patients diagnosed as havin
219 I trials confirmed the benefit of concurrent chemoradiation over radiation therapy alone, firmly esta
220 suggested an OS advantage for postoperative chemoradiation over surgery alone, although prospective
221 towards studies of adjuvant chemotherapy and chemoradiation, particularly in defining the best regime
224 nts with cN- tumors treated with neoadjuvant chemoradiation plus surgery do not derive a significant
225 hese reasons, the use of chemotherapy and/or chemoradiation prior to surgery (neoadjuvant therapy) is
230 vorably with AFX-C alone or other concurrent chemoradiation regimens tested by the Radiation Therapy
231 logies, the inclusion of newer agents to the chemoradiation regimens, the use of new hypoxic cell rad
236 dual population of cells escapes surgery and chemoradiation, resulting in a typically fatal tumor rec
241 a taxane followed by radiation or concurrent chemoradiation show that the three-drug induction chemot
242 ychological testing of patients treated with chemoradiation shows significant cognitive deficits that
243 therapy, providing an opportunity to deliver chemoradiation specifically to metastatic disease in col
244 X or gemcitabine/nab-paclitaxel) followed by chemoradiation (standard group) or the same standard neo
246 growth factor receptor (EGFR) inhibition in chemoradiation strategies in the nonoperative treatment
247 s consist of surgical resection and adjuvant chemoradiation; such approaches are often associated wit
248 from 2010 to 2014, who underwent neoadjuvant chemoradiation, surgical resection, and adjuvant therapy
250 stage I-III NSCLC and candidates for radical chemoradiation therapy (60 Gy in 30 fractions over 6 wk)
255 Of 63 cases, 39 (62%) patients received chemoradiation therapy and 24 (38%) received chemotherap
256 once per week; n = 221) for 3 weeks prior to chemoradiation therapy and for 12 weeks after chemoradia
257 patients following fluorouracil (5-FU)-based chemoradiation therapy and provide evidence for a functi
258 ent induction chemotherapy, and 52% received chemoradiation therapy as well for a median of 6 months
259 ts with HNSCC who were treated by concurrent chemoradiation therapy between March 2002 and December 2
261 the benefit of cetuximab added to concurrent chemoradiation therapy for patients undergoing nonoperat
262 rior to and following neoadjuvant 5-FU-based chemoradiation therapy in a series of colorectal cancer
263 )F-FLT) before and early after initiation of chemoradiation therapy in patients with squamous cell he
265 mall-cell lung cancer (NSCLC) during radical chemoradiation therapy using serial PET/CT with (18)F-FD
266 racellular amplification of chemotherapy and chemoradiation therapy via gold nanoparticle- and laser
267 latin and docetaxel, followed by concomitant chemoradiation therapy with cisplatin, docetaxel, and 45
268 with glioblastoma who had completed standard chemoradiation therapy, adding TTFields to maintenance t
269 risk of recurrence (including chemotherapy, chemoradiation therapy, and molecular targeted therapies
270 to predict patient responses to neoadjuvant chemoradiation therapy, paving the way toward a new para
271 ts treated with preoperative chemotherapy or chemoradiation therapy, we also demonstrate for the firs
279 imen of preoperative staging and neoadjuvant chemoradiation treatment followed by orthotopic liver tr
280 The addition of bevacizumab to standard chemoradiation treatment for patients with nasopharyngea
282 cts (ten [26%] vs four [12%], p=0.12) during chemoradiation treatment; the most frequent events were
283 denocarcinoma (EAC) is resistant to standard chemoradiation treatments, and few targeted therapies ar
284 rboplatin once a week (AUC 2); 2 weeks after chemoradiation, two cycles of consolidation chemotherapy
287 e phase II clinical trials of cediranib with chemoradiation vs. chemoradiation alone in nGBM patients
288 ival for the 79 patients who completed chemo-chemoradiation was 18.7 months, with a median survival o
290 f gemcitabine to adjuvant fluorouracil-based chemoradiation was associated with a survival benefit fo
291 sonidazole dynamics between weeks 0 and 2 of chemoradiation was associated with improved LRC (HR, 0.3
292 (PDI) as a target to overcome resistance to chemoradiation, we developed a GBM tumor model wherein c
293 accompanied by decreases in no treatment and chemoradiation, whereas the rate of esophagectomies rema
299 ced rectal cancers may tolerate preoperative chemoradiation with IGRT as well as younger patients.