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1 in-A1, and NP1 that impedes their ability to chemotax.
4 on, a loss of the ability to phagocytose and chemotax, and decreased expression of chemokine mRNAs.
5 ved factor (SDF1)alpha, it triggers cells to chemotax, and in some cell types such as neurons, causes
9 biological contexts, from the trajectory of chemotaxing bacteria to the nuclear mobility inferred fr
11 y production/destruction of secreted cAMP in chemotaxing cells accounts for the observed oscillatory
12 GAP1, which localizes at the leading edge of chemotaxing cells and is activated by and essential for
13 ly, as the myosin II cap in the posterior of chemotaxing cells and myosin II assembly into cytoskelet
14 localizes at the leading edge and uropod of chemotaxing cells and the B domain of WASP is required f
16 ynamic alteration of chemoattractant flux by chemotaxing cells provides an efficient way to solve com
20 anner and is enriched at the leading edge of chemotaxing cells where it regulates F-actin dynamics an
21 Ras activation occurs at the leading edge of chemotaxing cells, and this local activation is independ
22 -actin in pseudopods at the front of motile, chemotaxing cells, but is not present in filopodia or at
23 dels have captured some of these features of chemotaxing cells, but no system has explained the compl
25 ctant stimulation and to the leading edge in chemotaxing cells, PTEN, a negative regulator of PI3K pa
27 tructure of cells and is highly polarized in chemotaxing cells, with F-actin assembled predominantly
41 ver, show that even when single cells do not chemotax, clusters of cells may, if their interactions a
42 d pathways interact to establish polarity in chemotaxing D. discoideum cells by localizing F-actin at
43 stigated WASP function and its regulation in chemotaxing Dictyostelium cells and demonstrated the spe
45 sure the three-dimensional forces exerted by chemotaxing Dictyostelium cells, and examined wild-type
51 ce to EGF stimulation, demonstrating that to chemotax efficiently, a cell must be able to respond to
53 , mature neutrophils from -/- mice failed to chemotax in vitro and failed to mobilize into peripheral
54 rvae can move up or down gradients of odors (chemotax), light (phototax), and temperature (thermotax)
61 ith only a single functional OSN are able to chemotax robustly, demonstrating that chemotaxis is poss
62 n of Dd-STATa null cells is delayed and they chemotax slowly to a cyclic AMP source, suggesting a rol
63 a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a
65 f human neutrophils so that they are able to chemotax through a higher-concentration range of chemoat
69 The resulting sextuple mutant is able to chemotax to cyclic-AMP with near wild-type efficiency an
71 dr-2 mutants are defective in the ability to chemotax to odorants that are recognized by the two AWC
72 emales from two species in the Elegans group chemotax to volatile odor from males, but hermaphrodites
73 of cells at different developmental stages, chemotaxing to either folate or cyclic AMP and moving wi
74 starvation, individual Dictyostelium amoebae chemotax toward aggregation centers in tightly packed st
76 r chemotaxis and phagocytosis; Dictyostelium chemotax toward bacteria and phagocytose them as food so
80 We pay close attention to how immune cells chemotax toward pro-inflammatory mediators, presenting a
81 lassic back-of-the-wave problem is how cells chemotax toward the wave source, even though the spatial
82 n proteins, or active motor function did not chemotax toward tumor cylindroids, indicating that direc
85 oral dynamics of traction forces measured in chemotaxing unicellular amoeba, Dictyostelium discoideum
86 R knockouts could still spread, migrate, and chemotax using pseudopods driven by the Arp2/3 complex.