ライフサイエンスコーパス: childhood

1 fat consumption with fracture risk in later childhood.

2 on is common after IOL implantation in early childhood.

3 tric regression, at least from early to late childhood.

4 Source memory improves substantially during childhood.

5 in FE compared with IE trajectory throughout childhood.

6 ry common condition that typically starts in childhood.

7 autoantibodies against (pro)insulin in early childhood.

8 e with decreased allergic disease risks over childhood.

9 ng young adults treated for PCG during early childhood.

10 rrent fever attack once in 1-2 months during childhood.

11 e metabolic association with rapid growth in childhood.

12 five patients had hepatitis-like episodes in childhood.

13 esponsiveness of children to norms in middle childhood.

14 uation sensitivity and aggression control in childhood.

15 consequences of socioeconomic inequality in childhood.

16 oking in childhood and, especially, in early childhood.

17 in a trend for reduction in asthma rates mid-childhood.

18 in-releasing hormone (GnRH) secretion during childhood.

19 ises experiences of abuse and neglect during childhood.

20 n from middle (7 to 9 y) to late (9 to 11 y) childhood.

21 with cardiometabolic risk factors already in childhood.

22 scaffolding the process of maturation during childhood.

23 like symptoms that affect girls during early childhood.

24 ry) is related to hippocampal development in childhood.

25 equalities in health and mortality begins in childhood.

26 ebellar tumor predominantly diagnosed during childhood.

27 ubsequent anxiety and depression symptoms in childhood.

28 3 years and asthma that persisted throughout childhood.

29 strophy and affects boys in infancy or early childhood.

30 ry of allergic conditions during infancy and childhood.

31 Copenhagen Prospective Studies on Asthma in Childhood 2010(2010) mother-child cohort of 700 children

32 Copenhagen Prospective Studies of Asthma in Childhood-2010 mother-child cohort were examined for imm

33 paired health and educational achievement in childhood(4,5) and with a range of diseases in later lif

34 light on why sleep is important during early childhood, a period of substantial brain development.

35 awasaki disease (KD) is the leading cause of childhood acquired heart disease in developed nations an

36 Although the cure rate for childhood acute lymphoblastic leukemia (ALL) has exceede

37 res, has improved 5-year overall survival of childhood acute lymphoblastic leukemia (ALL) to 90%, but

38 In 5% of childhood acute lymphoblastic leukemia (ALL), the t(1,19

39 nd neurocognitive impairment in survivors of childhood acute lymphoblastic leukemia.

40 everal studies report that adolescents whose childhood ADHD symptoms have remitted are indistinguisha

41 wo unrelated, consanguineous families with a childhood/adolescence onset of a myopathy associated wit

42 We conclude that avoiding childhood/adolescence secondhand smoke exposure promotes

43 ance recommendations for female survivors of childhood, adolescent, and young adult cancer.

44 uished between three different dimensions of childhood adversities: poverty and material deprivation,

45 influences may contribute to the exposure to childhood adversity, resulting in potential genetic conf

46 ocognitive outcomes among 6,148 survivors of childhood ALL (median age, 27.9 years; range, 5.9-61.9 y

47 ear survivors of contemporary, standard-risk childhood ALL are comparable to the general population.

48 Subsequent childhood allergic disease was assessed by parent report

49 psychosocial distress increases the risk for childhood allergic disease.

50 economic and psychosocial experiences during childhood and (ii) socioeconomic conditions, (iii) healt

51 o +5.25) spherical equivalent diopter (D) in childhood and -0.25/-0.25 (-12 to +2.75/-13.25 to +2.63)

52 detect hippocampal development during middle childhood and adolescence are not sensitive enough.

53 socioeconomically disadvantaged area during childhood and adolescence has a long-lasting negative as

54 al repertoire of the developing brain during childhood and adolescence is shaped by complex brain-env

55 iving in a disadvantaged neighborhood during childhood and adolescence was associated with a higher l

56 that childhood asthma often improves between childhood and adolescence, but refractory cases have bee

57 between the genetic contributions to infant, childhood and adult adiposity.

58 ificity, and measures of association between childhood and adulthood blood pressure; reduction of chi

59 We assessed whether early childhood and adulthood experiences of neighborhood priv

60 Environmental influences measured in childhood and adulthood had small but significant effect

61 indings support independent effects of early childhood and adulthood neighborhood privilege on preter

62 face area differences among all disorders in childhood and adulthood.

63 rs apart had significantly distinct diets in childhood and adulthood.

64 As (n-3 LCPUFAs) accrete in the brain during childhood and affect brain development.

65 anisms, which show protracted development in childhood and are affected by language use, expertise, a

66 cohorts and normally distributed throughout childhood and early adulthood.

67 ght the need for long-term screening of both childhood and early-adolescent and young adult cancer su

68 areas, initial infection can occur in early childhood and following a recurrent episodes, it progres

69 icate an association between hypertension in childhood and hypertension in adulthood.

70 memory abilities continue to develop across childhood and into adolescence, studying episodic memory

71 it undergoes significant development during childhood and is extremely reactive to stress.

72 d be considered in the investigation of both childhood and juvenile open-angle glaucoma, particularly

73 individual differences in working memory in childhood and lay the groundwork for characterizing the

74 dietary patterns and their associations with childhood and parental factors.

75 ify different rhinitis trajectories in early childhood and their predictors and allergic associations

76 e adult hazards of having started smoking in childhood and, especially, in early childhood.

77 ally experienced similar environments during childhood, and exhibit negligible population stratificat

78 s health from the prenatal period throughout childhood, and many diseases have been associated with d

79 contributes to the development of AR during childhood, and this trajectory is mediated, at least in

80 Starting in childhood approximately doubled the rate of premature de

81 Recurrent wheeze and asthma in childhood are commons causes of chronic respiratory morb

82 important part of the evaluation of FASD in childhood as well as in young adulthood.

83 e results suggest a novel mechanism of early childhood asthma and demonstrates the importance of phen

84 dae Enterovirus, is strongly associated with childhood asthma exacerbations.

85 Risk for childhood asthma is conferred by alleles within the 17q2

86 It has been noted that childhood asthma often improves between childhood and ad

87 ing the risk conferred by maternal asthma on childhood asthma or recurrent wheeze development.

88 gnancies in women with and without asthma on childhood asthma or recurrent wheeze development.

89 iet can be a promising strategy for reducing childhood asthma risk.

90 Current childhood asthma therapies have little effect on lung fu

91 lish a clear association between nonallergic childhood asthma, lower whole-blood sphingolipids, and a

92 ome during illnesses were related to risk of childhood asthma.

93 Childhood attention deficit hyperactivity disorder (ADHD

94 ons (CNV), associated with novel subtypes of childhood B-ALL, have prognostic significance.

95 ce of the reproductive endocrine axis during childhood before its reawakening at puberty had been eni

96 Copenhagen Prospective Studies on Asthma in Childhood birth cohort.

97 uscular dystrophy to spastic paraplegia to a childhood blinding disorder to bone deformations.

98 ar malformations accounting for up to 10% of childhood blindness (~1 in 5000 live birth).

99 nopathy of prematurity is a leading cause of childhood blindness worldwide, but clinical diagnosis is

100 justing for covariates, each 5-mug/dL higher childhood blood lead level was significantly associated

101 d and adulthood blood pressure; reduction of childhood blood pressure; adverse effects of treatments.

102 OH)D at age 1 y is inversely associated with childhood BMIZ, percentage body fat at age 16/17 y, and

103 e linear regression models (adjusted for mid-childhood body mass index z scores, maternal education,

104 viduals who had developed cataracts later in childhood: both groups exhibited the typical bias of per

105 abdoid tumor (AT/RT) is an aggressive, early-childhood brain tumor without standard effective treatme

106 off-target effects on the normal developing childhood brain.

107 T) and B(T) /A within safe limits throughout childhood, but B(T) increased 0.46 mg/dL per year to rea

108 minance-defined gratings reached maturity in childhood by the ages of 9-10 years for all SFs (0.5, 1,

109 Influenza virus exposures in childhood can establish long-lived memory B cell respons

110 r risk was based on survivors diagnosed with childhood cancer between 1970 and 1986.

111 Although a diagnosis of childhood cancer can have a profound effect on the entir

112 The International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) re

113 available, the International Late Effects of Childhood Cancer Guideline Harmonization Group has updat

114 e female US and Canadian participants in the Childhood Cancer Survivor Study (CCSS) cohort and valida

115 the late effects of cancer therapy) than did childhood cancer survivors (SMR 4.8 [95% CI 4.4-5.1] vs

116 Exercise intolerance is prevalent among childhood cancer survivors and associated with all-cause

117 Childhood cancer survivors reported a higher prevalence

118 lescent and young adult cancer survivors and childhood cancer survivors were both at greater risk of

119 adult cancer survivors and 5.6 [4.9-6.3] for childhood cancer survivors), and at increased risk of de

120 To assess the risk of ESKD among childhood cancer survivors, we conducted a nationwide, p

121 dolescent and young adult survivors than for childhood cancer survivors.

122 Survivors of childhood cancer treated with anthracyclines and/or ches

123 enesis among nonirradiated male survivors of childhood cancer, but there is substantial variation in

124 tand Foundation, the Mia Neri Foundation for Childhood Cancer, Cassa di Sovvenzioni e Risparmio fra i

125 , are key mediators of tumorigenesis in this childhood cancer.

126 tion of tumor cells remains underexplored in childhood cancer.

127 otential study in combinatorial regimens for childhood cancer.

128 lations, is not well studied in survivors of childhood cancer.

129 l adverse effects, congenital birth defects, childhood cancer.

130 m an evolutionary standpoint, some high-risk childhood cancers are born bad, whereas others grow wors

131 rials have tested immune-based approaches in childhood cancers, few have been guided by biomarkers or

132 nationals and prioritises breast cancer and childhood cancers.

133 Early childhood caries (ECC) is a largely preventable conditio

134 efractive error alone accounted for 68.9% of childhood cases.

135 atial ability remained after controlling for childhood cognitive ability.

136 illness and are more likely to emerge during childhood compared with most other psychiatric disorders

137 cCMV greater than many other well recognized childhood conditions.

138 t identify a protective association of early childhood cow's milk volume or fat consumption with frac

139 malaria, accounting for the vast majority of childhood deaths from malaria despite highly effective a

140 ctivity and the study setting, in which most childhood deaths were due to infections.

141 Early childhood deprivation is associated with higher rates of

142 The impact of childhood deprivation on the adult brain and the extent

143 Early childhood development (ECD) programmes can help address

144 e stratified by ADPKD diagnosis at age <=18 (childhood diagnosis [CD]) or>18 (adulthood diagnosis [AD

145 from enamel carbonates and dentin collagen (childhood diet) and dental microwear texture analysis (a

146 ccurs in utero, during infancy, and in early childhood, diminishing throughout life.

147 and extend understanding of this intractable childhood disease.

148 c viral infections predominated as causes of childhood encephalitis in Australia.

149 Childhood environment can have a profound impact on brai

150 We discuss why the influence of the childhood environment on adult reproductive function is

151 mbryonic development and have been linked to childhood epilepsy before, but the underlying mechanisms

152 safety data from clinical trials outside of childhood epilepsy syndromes and from studies of over-th

153 Childhood epilepsy with centrotemporal spikes, previousl

154 sy, is one of the most common forms of focal childhood epilepsy.

155 er-order memory and cognition already during childhood, even if still subject to ongoing maturation.

156 h distinct lifestyles and following specific childhood events, and point to a role for the early-life

157 adult reproductive function can be shaped by childhood events.

158 Experiencing multiple adverse childhood experiences (ACEs) is a risk factor for many a

159 atio range=1.25-1.43), and number of adverse childhood experiences (adjusted odds ratio range=1.04-1.

160 we aimed to describe trajectories of adverse childhood experiences and relate these to overall and ca

161 mental model traces the pathway from adverse childhood experiences and stress to disruption of the de

162 ldren and responses to the impact of adverse childhood experiences, and (c) whether services matter a

163 We estimated 77 prenatal exposures and 96 childhood exposures (cross-sectionally), including indoo

164 We assessed whether pregnancy and childhood exposures to air pollution are related to whit

165 For childhood exposures, the multiexposure model identified

166 levels of either alpha-T or gamma-T with mid-childhood FEV(1) or FVC.

167 lar DNA in neuroblastoma, a tumor arising in childhood from primitive cells of the sympathetic nervou

168 us on two key populations: children in early childhood (from birth to age 6) and parents in early adu

169 imate the incidence of primary and secondary childhood glaucoma in Scotland over a 2-year period.

170 ificantly better VF and VRQoL than secondary childhood glaucoma patients.

171 A total of 29 patients with history of childhood glaucoma, who were treated unilaterally with P

172 costs associated with obesity (especially in childhood), governments have tried several fiscal and po

173 used by mismatched binocular vision in early childhood has predominantly focused on circuits in the p

174 Stress exposures during childhood have been linked to altered hippocampal struct

175 Survivors of childhood hematologic malignancies (HSCT N = 112 [70% al

176 al immunization efforts, including universal childhood hepatitis A (HepA) vaccination recommendations

177 unidentified by the integrated management of childhood illness (IMCI) WHO protocol.

178 specific child mortality impact estimates of childhood immunisation for diphtheria, tetanus, pertussi

179 The deaths prevented by sustaining routine childhood immunisation in Africa outweigh the excess ris

180 re the health benefits of sustaining routine childhood immunisation in Africa with the risk of acquir

181 Routine childhood immunisation should be sustained in Africa as

182 Waning public support for childhood immunization and subsequent recent outbreaks o

183 Childhood immunization with the live-attenuated varicell

184 ffect in offspring of mothers exposed during childhood implicates maternal developmental programming

185 ion exposures during pregnancy, infancy, and childhood in a UK population-based birth cohort.Methods:

186 cCMVI is an important cause of HL in childhood in all settings.

187 atal growth on Intelligence Quotient (IQ) in childhood in term-born children living in high-income co

188 d the relationship between mode of birth and childhood infection-related hospitalisation in high-inco

189 twin design after accounting for measures of childhood intelligence (IQ), negative affect, and prior

190 f action of Fast Track (FT), a comprehensive childhood intervention designed to decrease aggression a

191 first 5 y of life was associated with higher childhood IQ whereas greater weight gain after the first

192 Childhood is a sensitive period with rapid brain develop

193 xposure impairs lung-function development in childhood, it remains a challenge to use this informatio

194 Childhood learning difficulties and developmental disord

195 ons of PRS with smoking during pregnancy and childhood life events in relation to CU-traits.

196 , dopaminergic PRS appeared to interact with childhood life events in relation to unemotional scores.

197 born controls or those arriving during early childhood, likely because of environmental and lifestyle

198 mmune System and Development of Allergies in Childhood (LISA)/German Infant Study on the Influence of

199 ly childhood or in utero are associated with childhood lung function.

200 Childhood maltreatment (CM) comprises experiences of abu

201 e coping skills in the relationships between childhood maltreatment and both psychological distress a

202 ventions for psychopathology associated with childhood maltreatment can benefit from deeper understan

203 maltreatment and subjective reports of their childhood maltreatment histories made once they reached

204 We found that, even for severe cases of childhood maltreatment identified through court records,

205 There is little research on how childhood maltreatment influences the use of resilience

206 It is well established that childhood maltreatment is a significant risk factor for

207 tially mediated the negative consequences of childhood maltreatment on mental health outcomes.

208 though we know that female sex, a history of childhood maltreatment, and family history as well as mo

209 were used to model the relationships between childhood maltreatment, social support, and positive cop

210 at may mediate these relationships following childhood maltreatment.

211 during intrauterine development and through childhood may have lasting effects on respiratory health

212 altered microbiota at birth and later on in childhood may influence disease risk; and the prospects

213 physiological growth, and adverse events in childhood might interfere with these processes and have

214 iratory infections (ALRIs), with significant childhood morbidity and mortality worldwide.

215 Diphtheria, once a major cause of childhood morbidity and mortality, all but disappeared f

216 Malaria causes tremendous early childhood morbidity and mortality, providing an urgent i

217 Influenza contributes significantly to childhood morbidity and mortality.

218 nd diseases, with important implications for childhood mortality particularly in low-income settings.

219 coexist in children, but compared to adults, childhood multimorbidity attracts less attention in rese

220 myopathies (RYR1-RMs) are a common group of childhood muscle diseases associated with severe disabil

221 skin infections were common, particularly in childhood (n = 12).

222 miological evidence for the genetic basis of childhood neurodevelopment is very limited.

223 Childhood obesity has become a global pandemic in develo

224 We estimate that the impact on childhood obesity of this policy may be reduced by aroun

225 will reduce the public health burden of the childhood obesity pandemic.

226 Despite the rising incidence of childhood obesity, international data from Eurostat show

227 e the impact of maternal prepregnancy BMI on childhood obesity, which warrants further investigation

228 ilk for children might not lower the risk of childhood obesity.

229 ehavior in later life and is associated with childhood obesity.

230 d make a meaningful contribution to reducing childhood obesity.

231 A childhood onset of autosomal dominant CMT2A is the most

232 with chronic isolated proteinuria and early childhood onset.

233 prototypical yet poorly understood forms of childhood-onset and complex hereditary spastic paraplegi

234 Childhood-onset cardiomyopathy is a heterogeneous group

235 nant BAG3-P209L mutation results in a severe childhood-onset myofibrillar myopathy (MFM) associated w

236 In conclusion, we describe a novel childhood-onset neurometabolic disease caused by choline

237 th bi-allelic variants in UNC45B who exhibit childhood-onset progressive muscle weakness.

238 his approach may be applicable in other rare childhood ophthalmic disorders.

239 3 neuroimaging samples (N = 2423), spanning childhood or adolescence to middle age, with prospective

240 hy and the type of initial management during childhood or before transplantation.

241 tocopherol (gamma-T) isoform levels in early childhood or in utero are associated with childhood lung

242 mes but was associated with a higher risk of childhood overweight (odds ratio [OR] 1.17 [95% CI 1.02-

243 others, paternal smoking was associated with childhood overweight (OR 1.21 [95% CI 1.16-1.27], P valu

244 on (SD) units) had a strong association with childhood overweight [Odds ratio (OR): 2.01 (95% confide

245 , puberty, and age 30 years with offspring's childhood overweight status (potential mediator) and off

246 r gestational age, but with a higher risk of childhood overweight.

247 pact of pulse oximetry use during infant and childhood pneumonia management at the primary healthcare

248 Despite several risk factors during childhood predicting the persistence of ADHD symptoms in

249 e measures of neonatal CB microstructure and childhood preterm behavioral phenotype symptoms (n = 56

250 genic risk scores (PRS) and a broad range of childhood psychiatric symptoms, and to quantify the exte

251 ons can be attributed to a general factor of childhood psychopathology.

252 irect effect of early intervention on middle childhood psychosocial functioning mediated through incr

253 understanding of the everyday-life impact of childhood residual amblyopia.

254 The natural history of childhood rhinitis is not well described.

255 ons and structural variants) responsible for childhood severe obesity remains elusive.

256 timulation to measure T cells elicited after childhood smallpox vaccination.

257 lantation had not been accessible during her childhood, so she had been submitted to monthly blood tr

258 High childhood socioeconomic disadvantage was also associated

259 Childhood socioeconomic disadvantage was assessed using

260 High childhood socioeconomic disadvantage was associated with

261 Rhabdomyosarcoma is the most common childhood soft-tissue sarcoma, yet patients with metasta

262 is linked to adverse consequences including childhood stunting and death from other diseases.

263 thods framework for studying determinants of childhood stunting reduction applied in Exemplars studie

264 Several countries have notably reduced childhood stunting relative to economic growth over the

265 g children and have been linked to increased childhood stunting.

266 trophic lateral sclerosis (ALS), as early as childhood, suggesting these pathways are involved in dis

267 , and to the prenatal origin of disorders of childhood that involve disruptions in large-scale networ

268 gic asthma is a chronic disease beginning in childhood that is characterized by dominant T-helper 2 c

269 placed with excessive feeding and obesity in childhood through adulthood.

270 ding a possible increase in the incidence of childhood thyroid cancer.

271 hrenia with 2,137 observations spanning from childhood to 20 years after first admission.

272 ical activity and higher sedentary time from childhood to adulthood.

273 observed in women whose BMI normalized from childhood to adulthood: RR was 2.04 (95% CI: 0.93, 4.47)

274 on was associated with cognitive change from childhood to age 70 (standardized beta = 0.100).

275 to evaluate dietary taste patterns in early childhood, to examine their tracking between the ages of

276 estimate dissociation, after controlling for childhood trauma and PTSD severity.

277 chiatric comorbidity and symptomatology, and childhood trauma exposure were assessed.

278 posure) and offspring characteristics (i.e., childhood trauma exposure, lifetime psychiatric diagnose

279 notype showed a significant interaction with childhood trauma in predicting worse symptom severity.

280 lity, aggressive or impulsive traits explain childhood trauma's effects on SI variability and whether

281 This study tested whether childhood trauma, affective lability, and aggressive and

282 Childhood tumors that occur synchronously in different a

283 eta-cell autoantigens is a characteristic of childhood type 1 diabetes (T1D).

284 Childhood undernutrition is associated with dysbiosis an

285 testine that is postulated to play a role in childhood undernutrition, a pressing global health probl

286 at participants' homes during pregnancy and childhood using land-use regression models.

287 Universal childhood vaccination against varicella began in the Uni

288 ths averted before 5 years of age by routine childhood vaccination during a 6-month COVID-19 risk per

289 This article describes a reduction in childhood vaccinations during the COVID-19 pandemic, whi

290 panded Program on Immunization are universal childhood vaccines (eg, measles and rotavirus vaccines).

291 ) of healthy young adults (n = 15) following childhood VZV immunization.

292 Height and head circumference growth in childhood was associated with IQ [per z-score increase f

293 ough there has been focus on rising rates of childhood wasting in the short term, maternal and child

294 ned how birth size and growth in infancy and childhood were associated with IQ at age 5 y in term-bor

295 f several air pollutants during pregnancy or childhood were associated with significantly lower FA or

296 regulation following social feedback during childhood, while this is an important period for both br

297 trajectories of severe exacerbations during childhood with different early-life risk factors and ast

298 insulin resistance (IR) and usually death in childhood, with few effective therapeutic options.

299 by increases in GM and persisted throughout childhood without evidence of volumetric regression or n

300 outcomes included more inpatient days during childhood, younger age at Fontan surgery, and longer tim