ライフサイエンスコーパス: chimeric mice

1 combined immune deficiency (uPA-SCID) mice" (chimeric mice).

2 g their pluripotency and ability to generate chimeric mice.

3 increased MDSC accumulation in the recipient chimeric mice.

4 tween C57BL/6J and Vwf(-/-) mice to generate chimeric mice.

5 shed the HBV replication in human hepatocyte-chimeric mice.

6 ies in the human hepatocytes in FIAU-treated chimeric mice.

7 topoietic cells was evaluated in bone marrow chimeric mice.

8 Wid-type, neogenin deficient and chimeric mice.

9 ection and subsequent demyelination of these chimeric mice.

10 and support the generation of teratomas and chimeric mice.

11 nal-associated Nlrp3 by studying bone marrow chimeric mice.

12 ying HBV-infected and uninfected human liver chimeric mice.

13 NTN was then investigated using bone marrow chimeric mice.

14 K cells similarly in young mixed bone marrow chimeric mice.

15 rtex, amygdala, and hippocampus of GFP(+) BM-chimeric mice.

16 type HSPCs proliferated in mixed bone marrow chimeric mice.

17 L-10 receptor deletion mice, and bone marrow chimeric mice.

18 and the CNS during EAE, we used bone marrow chimeric mice.

19 SHIP-1(-/-) animals and disease induction in chimeric mice.

20 d in vitro and in vivo using NOX1 or NOX2 BM chimeric mice.

21 lls or nonhematopoietic cells in bone marrow chimeric mice.

22 ause impaired recognition memory in neuronal chimeric mice.

23 hich encodes properdin) and by generating BM chimeric mice.

24 ly protective immune response in bone marrow chimeric mice.

25 irus dose is required to consistently infect chimeric mice.

26 te-deficient Rag2(-/)(-) mice, and generated chimeric mice.

27 ains, and improves behavioral deficits in DS chimeric mice.

28 rast-treated green fluorescent protein (GFP) chimeric mice.

29 rol mice, but not in WT or DREAM bone marrow chimeric mice.

30 en motor neurons could be detected in intact chimeric mice.

31 macrophages differentiated from the BM of UV-chimeric mice.

32 s were performed in vitro and in human liver chimeric mice.

33 opathology compared with wild-type (WT)-->WT chimeric mice.

34 ells, as demonstrated with mixed bone marrow chimeric mice.

35 ifferentiated teratomas, and cannot generate chimeric mice.

36 eduction of plaque size in NK-cell-deficient chimeric mice.

37 ity in vitro and in HBV-infected human liver chimeric mice.

38 Rbeta(+/+) counterparts in mixed bone marrow chimeric mice.

39 lammatory compared to plaques of Trem-1(+/+) chimeric mice.

40 Our results with P2X7(-/-) bone marrow chimeric mice, adoptive transfer of peritoneal macrophag

41 CV infected (GT1a and GT3a) human hepatocyte chimeric mice after 7 days of oral administration of 9.

42 type, Cd39 ectonucleotidase-null mice and in chimeric mice after transplantation of wild-type or Cd39

43 KLF12-deficient NK cells from bone marrow chimeric mice also expressed higher levels of the IL-21R

44 Similarly, human hepatocytes in chimeric mice also gave rise to biliary progenitors in v

45 acrophages differentiating from the BM of UV-chimeric mice also had an inherent reduced ability to mi

46 effector responses in both mixed bone marrow-chimeric mice and adoptive cell transfer experiments.

47 Indeed, in chimeric mice and after adoptive transfer, wild type T c

48 e way for more widespread use of human liver chimeric mice and forms the basis for creating increasin

49 In vivo studies using bone marrow chimeric mice and in vitro studies of neutrophil activat

50 using B6/Langerin-diphtheria toxin receptor chimeric mice and LC ablation, we demonstrated that epid

51 ela(+/-) neutrophils in peritonitis in mixed chimeric mice and neutrophilia in Crel(-/-)Nfkappab1(-/-

52 Chimeric mice and parabiosis experiments indicated that

53 By generating chimeric mice and performing skin reconstitution assays

54 study, we used immune competent bone marrow chimeric mice and syngeneic orthotopic mammary cancer mo

55 on iNKT cells using germline-deficient mice, chimeric mice, and conditionally deficient mice.

56 ve erythroblasts develop normally in vivo in chimeric mice, and Hb Null erythroid cells undergo enucl

57 Human liver chimeric mice are a step forward in this regard, as the

58 for preclinical drug development.Human liver chimeric mice are increasingly used for drug testing in

59 die neonatally, but Orai1(KI/KI) fetal liver chimeric mice are viable and show normal lymphocyte deve

60 LTP) was sharply enhanced in the human glial chimeric mice, as was their learning, as assessed by Bar

61 e mAbs, K04, was administered to human liver chimeric mice before or after HCV infection to determine

62 Generation and immunization of reciprocal chimeric mice between BALB/c and B10.D2 strains revealed

63 -specific effects in vivo, we generated CD36 chimeric mice by bone marrow transplantation and evaluat

64 n interlaminar astrocytes in humanized glial chimeric mice by engrafting astrocytes differentiated fr

65 VDR deficiency, we produced bone marrow (BM)-chimeric mice by transplanting lethally irradiated C57BL

66 In BM chimeric mice (C57BL/6 with tandem dimer Tomato-positive

67 iously reported that Rora(sg/sg) bone marrow chimeric mice (C57BL/6J) were protected from Salmonella-

68 Furthermore, chimeric mice can be generated by injecting these mESCs

69 Compared with control Ldlr(-/-) chimeric mice, CD11c-Cre x Tcf4(-/flox) mice had reduced

70 We then generated chimeric mice (Cdk5(+/+C) or Cdk5(-/-C)) using hematopoi

71 ificantly less than that measured in control-chimeric mice challenged with the same inflammatory agen

72 ection over the calvaria of NLRP12-deficient chimeric mice compared with wild-type control mice.

73 Bone marrow chimeric mice confirmed that CX3CR1 deficiency in bone m

74 Studies of OVA-treated Adam8 bone marrow chimeric mice confirmed that leukocyte-derived Adam8 pre

75 e spectrum of ILC2s in parabiotic and shield chimeric mice, consistent with their potential role in t

76 We observed that chimeric mice containing Ifnar-deficient hematopoietic c

77 Using chimeric mice containing wild-type or IL-21R(-/-) CD4 T

78 Using mixed chimeric mice, containing both wild-type and syk(f/f) MR

79 Bone marrow chimeric mice (Cxcr2(+/-)-->Cxcr2(-/-) and Cxcr2(+/-)-->

80 Chimeric mice deficient for Notch3 in hematopoietic cell

81 Reduced cardiac function was reproduced in chimeric mice deficient in bone marrow Mertk; reciprocal

82 The use of chimeric mice deficient in ICAM-1 on myeloid cells demon

83 Similar results were obtained in chimeric mice deficient in leukocyte TNF.

84 In contrast, chimeric mice deficient in TLR2 in the nonhematopoietic

85 SCs respond to TLR2 ligand, TLR2 bone marrow chimeric mice demonstrated that Kupffer cells were relat

86 Experiments conducted using bone marrow chimeric mice demonstrated that radio-resistant cells pa

87 ell transcription factor expression in mixed chimeric mice depended on neutrophil count, not iNKT cel

88 ts, our familial hypercholesterolaemia liver chimeric mice develop hypercholesterolaemia and a 'human

89 Fully mismatched chimeric mice developed antibody responses to nominal an

90 ter treatment with FIAU 400 mg/kg/d for 4 d, chimeric mice developed clinical and serologic evidence

91 Human liver-chimeric mice developed high-titer infections after inoc

92 that of IL-17RA(-/-) mice and of bone marrow chimeric mice devoid of IL-17 signaling in immune and Ku

93 Batf3(-/-) chimeric mice did not show lower Tcell or other leukocyt

94 n, naive CD4(+) T cells from USP9X knockdown chimeric mice display decreased cytokine production and

95 IFNAR KO Tregs from chimeric mice displayed a more naive phenotype, accompan

96 The MyD88(B-/-) chimeric mice exhibited an impairment of development of

97 TLR2 knockout (TLR2KO)-->TLR2KO bone marrow chimeric mice exhibited increased bacterial burden, diso

98 Il-18bp KO (donor)-> Il-18bp KO (recipient) chimeric mice exhibited more severe disease, with an enh

99 Interestingly, competitive mixed bone marrow chimeric mice exhibited reduced development of KLF12-def

100 was investigated using bone marrow (BM) from chimeric mice expressing luciferase (Col-Luc-->wt) or gr

101 Low-density lipoprotein receptor-deficient chimeric mice expressing or not expressing CD69 on eithe

102 intrinsic because Irf4-deficient B cells in chimeric mice failed to participate in the GC in respons

103 ransplantation revealed more liver damage in chimeric mice fed CTRL diet, but receiving the microbiot

104 and lymphoid organs of CD11c-DTR bone marrow chimeric mice for up to 24 h postinfection.

105 Under competing conditions in bone marrow chimeric mice, FoxO1 deficiency did not perturb clonal e

106 e viral inoculation completely protected all chimeric mice from infection with serum-derived HCV of d

107 Experiments in bone marrow chimeric mice further demonstrated that myeloid cells ar

108 iological properties of scars in fetal liver chimeric mice generated using connexin43 knockout donors

109 d macrophage trafficking was prevented in BM-chimeric mice generated with CCR2(KO) or CX3CR1(KO) dono

110 Chimeric mice generated with Gata3-deficient fetal liver

111 Here, we show that chimeric mice generated with Gata3-deficient fetal liver

112 Moreover, in chimeric mice generated with RanBPM(-/-) embryonic stem

113 We found that BTNL2(-/-) chimeric mice had a significant decrease in survival com

114 Chimeric mice had an increased proportion of CCR5(-/-) T

115 marrow from wild-type to Bmi1(-/-) mice, the chimeric mice had intermediate levels of pancreatic hypo

116 In the preliminary in vivo study in chimeric mice harboring the lamivudine/entecavir triple

117 Experiments based on bone marrow chimeric mice, however, demonstrated that inflammation i

118 mechanistic studies using mixed bone marrow chimeric mice identified that CD40 and CD70 but not CD80

119 o accumulated in the peritoneal cavity of UV-chimeric mice (ie, mice transplanted with BM from UV-irr

120 1-deficient compartment from the bone marrow chimeric mice (IL-21R knockout/wild-type).

121 or growth was also greatly accelerated in wt chimeric mice implanted with P2X7R-deficient bone marrow

122 er injury, and rapidly generated human liver chimeric mice in a reproducible and scalable fashion.

123 The use of chimeric mice in preclinical toxicology studies could im

124 tes not derived from iPS cells, we generated chimeric mice in which all hepatocytes were iPS cell der

125 These conditions allowed us to produce chimeric mice in which all mature B cells were derived e

126 ient (WASp(-/-)) mice without overt disease, chimeric mice in which only the B cell lineage lacks WAS

127 Bone marrow chimeric mice in which the entire hematopoietic compartm

128 the ischemic brain, we used bone marrow (BM) chimeric mice in which the middle cerebral artery was oc

129 In these chimeric mice, in vivo administration of IL-33 or -25 fa

130 In chimeric mice, in which B cells were present but could n

131 In both Abp1(-/-) and bone marrow chimeric mice, in which only B cells lack Abp1 expressio

132 ined for more than 3 months in the livers of chimeric mice, in which they underwent further maturatio

133 during regeneration because the recovery of chimeric mice, incapable of expressing p57 in HSPCs, phe

134 Liver fibrosis in chimeric mice indicated that NOX1 mediates the profibrog

135 imal tubule epithelial cells, and studies in chimeric mice indicated that the effects of TRPM2 are du

136 ale cells were detected in 50%-90% of female chimeric mice infected with H pylori strains; the presen

137 toneal regimen of fluoxazolevir in humanized chimeric mice infected with HCV genotypes 1b, 2a or 3 re

138 s, was able to suppress viral replication in chimeric mice infected with HCV GT1a by up to 2.5 log10

139 w be routinely carried out using human-liver-chimeric mice infused with human erythrocytes to generat

140 nfected humanized livers compared to control chimeric mice, irrespective of the human hepatocyte dono

141 In chimeric mice, lack of SIRP-alpha signaling conferred pr

142 Using bone marrow chimeric mice lacking ARHGAP25 in the hematopoietic comp

143 Mixed chimeric mice lacking B cell-derived granulocyte macroph

144 Chimeric mice lacking CD73 in tissue had larger cerebral

145 Chimeric mice lacking Cdk5 gene expression in hematopoie

146 creased endotoxin resistance, IFNAR(-/-) and chimeric mice lacking IFNAR in hematopoietic cells displ

147 Mixed bone marrow chimeric mice lacking IL-10 in dendritic cells showed mo

148 Chimeric mice lacking immune cell-specific CCR2 expressi

149 f retinopathy and allodynia were measured in chimeric mice lacking inducible nitric oxide synthase (i

150 To explore this, we utilized chimeric mice lacking Plxnb2 or Plxnd1.

151 rial burden and pulmonary immunopathology of chimeric mice lacking TLR2 in the hematopoietic compartm

152 Bone marrow chimeric mice lacking vimentin have reduced IL-1beta lev

153 Recent work involving neurologically chimeric mice may suggest that such worries are reasonab

154 -structural changes observed in FIAU-treated chimeric mice mirrored those of FIAU-treated human parti

155 In human-synovium chimeric mice, MRE11A(low) T cells were tissue-invasive

156 Nur77(-/-) chimeric mice on a Ldlr(-/-) background showed a 3-fold

157 de novo infection, HBV infected human liver chimeric mice or transgenic mice with integrated HBV gen

158 Using mixed bone marrow chimeric mice, our studies describe a multilayered role

159 ed moderately greater renal dysfunction than chimeric mice positive for IL-10 in dendritic cells.

160 In contrast, CD4-deficient chimeric mice possessing decay accelerating factor defic

161 ght-driven flexibility of period observed in chimeric mice provides a new perspective on the concept

162 Gnaq(-/-) chimeric mice rapidly develop arthritis as well as other

163 In addition, miR-155(-/-) bone marrow chimeric mice receiving allo-HCT and miR-155(-/-) DCs sh

164 terns of IL-7Ralpha expression on T cells in chimeric mice reconstituted with Adora2a(+/+) and Adora2

165 ferentially accumulated in mixed bone marrow chimeric mice reconstituted with allotypically marked NO

166 Second, transplantable tumors developing in chimeric mice reconstituted with bone marrow cells from

167 r BTNL2 during malaria infection, we studied chimeric mice reconstituted with BTNL2(-/-) or wild-type

168 This phenotype was also observed in chimeric mice reconstituted with Clec1b(fl/fl)PF4-Cre bo

169 Irradiated fetal liver chimeric mice reconstituted with Gimap5-deficient cells

170 Moreover, chimeric mice reconstituted with NLRP3-deficient hematop

171 showed greater atheroprotective activity in chimeric mice reconstituted with TET2-deficient cells th

172 in bone marrow-depleted IL10KO mice (IL10KO chimeric mice) reduced transverse aortic constriction-in

173 The best available human liver chimeric mice rely on cellular transplantation into mice

174 In vivo the loss of SOCE in stim1(-/-) chimeric mice results in marked susceptibility to bacter

175 with dectin-1(-/-)/WT reciprocal bone marrow chimeric mice revealed a requirement for dectin-1 in bot

176 TLR4 bone marrow chimeric mice revealed an equal contribution of TLR4 on

177 MDM2-TCR-engineered T cells into bone marrow chimeric mice revealed that Ag recognition in hematopoie

178 Testing bone marrow chimeric mice revealed that CD36 engagement on radioresi

179 Use of bone marrow chimeric mice revealed that CD39 expression on myeloid c

180 collate-induced peritonitis experiments with chimeric mice revealed that hematopoietic ppGalNAcT-1 is

181 Our study using bone marrow chimeric mice revealed that IFN-gamma production by brai

182 PECAM-1-KO and chimeric mice revealed that its metastasis-promoting eff

183 Bone marrow chimeric mice revealed that neutrophils were recruited b

184 Mixed chimeric mice revealed that the defective maturation and

185 Bone marrow chimeric mice revealed that the Fo B cell-intrinsic loss

186 Studies of chimeric mice revealed that the hematopoietic Plexin C1

187 dies in WT and STAT1 R274W mixed bone marrow chimeric mice revealed that the presence of WT leukocyte

188 Surprisingly, chimeric mice revealed that these effects were due to My

189 Analysis of bone marrow chimeric mice revealed that TLR and RLH signaling of rad

190 The use of bone marrow chimeric mice revealed the cellular sources of MMP-2 and

191 The use of bone marrow chimeric mice reveals that both an immune cell and a CNS

192 These human glial chimeric mice should permit us to define the specific co

193 Hematopoietic Cx43-deficient chimeric mice show reduced mitochondria transfer, which

194 udies of bleomycin-treated Mmp-8 bone marrow chimeric mice show that both leukocytes and lung parench

195 Bone marrow chimeric mice showed B cell intrinsic effect of ENPP1 se

196 In addition, bone marrow chimeric mice showed hematopoietic-derived factors were

197 Chimeric mice specifically lacking platelet VWF showed n

198 fluorescent protein-positive (GFP(+)) adult chimeric mice subjected to laser-induced retinal vessel

199 type, Emc10-deficient, and Emc10 bone marrow-chimeric mice subjected to transient coronary artery lig

200 Further experiments in bone marrow chimeric mice suggested that the dual and opposing roles

201 Analysis of bone marrow chimeric mice suggested that the pathogenic effect of Fa

202 n wild-type and Blimp-1CKO-mixed bone marrow chimeric mice, suggesting an intrinsic role for Blimp-1

203 hrombus formation was enhanced in blood from chimeric mice, suggesting that the hyperlipidemic enviro

204 n left ventricular tissue sections of IL10KO chimeric mice suggests that myofibroblasts were derived

205 Here we demonstrate that human-liver chimeric mice support recovery of recombinant progeny fo

206 l pH-buffering capacity, allergen-challenged chimeric mice that contained Car4(-/-) hematopoietic cel

207 Chimeric mice that lack IL7Ralpha only on nonhematopoiet

208 Bone marrow chimeric mice that lack NOS2 in either nonhematopoietic

209 Chimeric mice that lacked p53 in leukocytes sustained in

210 Irradiated bone marrow chimeric mice that were either IL-6-deficient mice recon

211 by rose Bengal and laser photocoagulation on chimeric mice that were reconstituted with GFP+ bone mar

212 However, in p50(+/+)/p50(-/-) chimeric mice the p50(-/-) B cells exhibited a significa

213 We vaccinated IL-1R1 bone marrow (BM) chimeric mice to determine whether IL-1R1 expression on

214 Here we used bone marrow chimeric mice to examine the effects of PD-L1 deficiency

215 ld-type and Irf4-deficient mixed bone marrow chimeric mice to investigate how and where IRF4 plays it

216 In this study, using bone marrow chimeric mice to restrict TLR4 signaling to either the S

217 four groups of bone marrow chimeric or sham chimeric mice to study the role of TLR4 on bone marrow o

218 Consistent with the result in chimeric mice, transfer of iNOS(+/+), but not iNOS(-/-),

219 Strikingly, chimeric mice transplanted with Mekk3(Deltaflox/-) BM ex

220 cZ(+) and desmin(+) pericytes confirmed that chimeric mice transplanted with Mekk3(Deltaflox/-) BM we

221 Chimeric mice transplanted with WT or SIRP-alpha(mut) bo

222 ose-dependent liver toxicity was detected in chimeric mice treated with FIAU 100, 25, or 2.5 mg/kg/d

223 s, gammadeltaT17 cells emerge in bone marrow chimeric mice upon induction of skin inflammation by top

224 LDLR in familial hypercholesterolaemia liver chimeric mice using an adeno-associated virus 9-based ge

225 en DCs were differentiated from the BM of UV-chimeric mice using FLT3 ligand or GM-CSF + IL-4, the ce

226 ur approach was to establish humanized glial chimeric mice using glial progenitor cells (GPCs) produc

227 Moreover, generating chimeric mice via UPRT(+) bone marrow transplants identi

228 When the dorsal skin of UV-chimeric mice was challenged with innate inflammatory ag

229 Furthermore, using bone marrow chimeric mice we demonstrate that LTi cells are the key

230 However, using chimeric mice we demonstrated that SHIP-1 expression is

231 grin and metalloprotease (ADAM)-17 radiation chimeric mice, we demonstrate for the first time that du

232 Using bone marrow chimeric mice, we demonstrate that an optimal response t

233 Using mixed bone marrow chimeric mice, we demonstrate that Nfil3 is critical for

234 Using gfp(+) bone marrow-transplant chimeric mice, we demonstrate that the MCP-1-recruited f

235 Using mixed bone marrow chimeric mice, we demonstrate that type I IFN sensitivit

236 reen fluorescent protein (GFP)(+/+) cells in chimeric mice, we demonstrated that Cdh5(-/-)GFP(+/+) HS

237 Using mixed bone marrow chimeric mice, we demonstrated that IL-33 deficiency res

238 Using chimeric mice, we dissect the early (innate) and late (c

239 Using chimeric mice, we found a critical role for GAS6 in epit

240 Using bone marrow chimeric mice, we found that both ILC-intrinsic and ILC-

241 ld-type (WT), TLR4-knockout, and bone marrow chimeric mice, we found that endotoxin is readily filter

242 Using bone marrow-transferred chimeric mice, we found that LMP7 in both bone marrow- a

243 Using mixed bone marrow chimeric mice, we identified a requirement for MyD88 in

244 Using chimeric mice, we show that DC-derived IL-2 is required

245 Finally, using mixed bone marrow chimeric mice, we show that IFN-gamma-dependent infectio

246 Using mixed bone marrow chimeric mice, we show that the impact of NKG2D deficien

247 Additionally, bone marrow chimeric mice were assessed for lung disease severity an

248 In the present study, chimeric mice were created through bone marrow transplan

249 To determine the bone marrow origin, chimeric mice were created with enhanced green fluoresce

250 d in vivo from the BM of UV-irradiated mice, chimeric mice were established.

251 Bone marrow-transplanted TLR2 chimeric mice were generated after the recipient mice we

252 Bone marrow chimeric mice were generated and subjected to cecal liga

253 In addition, chimeric mice were generated by bone marrow transplant t

254 Chimeric mice were generated by bone marrow transplantat

255 Chimeric mice were generated by injecting human haematop

256 The p47phox KO chimeric mice were generated by the combination of lipos

257 Reciprocal bone marrow chimeric mice were generated to compare hematopoietic an

258 Bone marrow chimeric mice were generated to confirm a causal role of

259 Green fluorescent protein (GFP)-chimeric mice were generated to distinguish resident (re

260 Human liver chimeric mice were infected with a mixture of wild-type

261 The diminished responses in UV-chimeric mice were not due to different numerical or pro

262 Chimeric mice were produced by injecting human NC cells

263 b-diphtheria toxin (DT) receptor bone marrow-chimeric mice were selectively depleted following treatm

264 These chimeric mice were then fed the Western-type diet (WD) f

265 ext, LysM-GFP(+) and GFP(+) bone marrow (BM)-chimeric mice were used to determine the neuroanatomical

266 es in CCR6-deficient mice and in bone marrow chimeric mice where CCR6 deficiency was limited to the B

267 fer to HLA-B( *)27:05(+) mice or bone marrow chimeric mice where HLA-B( *)27:05 was restricted to eit

268 oads were also observed in mixed bone marrow chimeric mice, where B cell-extrinsic effects of miR-155

269 nctional importance of Lp-PLA2, we generated chimeric mice whose bone marrow-derived leukocytes were

270 zed chimeric CD11c-DTR mice and is absent in chimeric mice with 50% normal bone marrow.

271 nd cytokines in wild-type and NGAL-deficient chimeric mice with anti-MPO antibody-induced NCGN.

272 on with anti-CD4 antibodies or generation of chimeric mice with B cells deficient in both WASp and My

273 C57BL/6J female chimeric mice with BMDCs from male donors that express g

274 Moreover, bone marrow chimeric mice with CD4 T cell-specific deletion of IL-10

275 Here we utilize chimeric mice with competent hematopoietic-driven immuni

276 etastasis in mice via BMDC recruitment using chimeric mice with deficiency in CXCR4 and VEGFR1-tyrosi

277 Inoculation of resulting simian liver chimeric mice with either HCV genotype 1a or 2a resulted

278 Chimeric mice with Grp78 deletion only in the hematopoie

279 hly efficient in both HBV-infected and naive chimeric mice with HDV titers rising up to 1 x 10E9 copi

280 In contrast, p65KO athymic chimeric mice with human GBM, failed to inhibit tumor gr

281 ore represent a major obstacle to generating chimeric mice with human xenografts that are useful tool

282 Bone marrow chimeric mice with IFN-gamma-unresponsive lung epithelia

283 WT chimeric mice with MKK-6- and MKK-3-deficient bone marro

284 We made bone marrow chimeric mice with MMP-9 null and wild-type as donor and

285 ls, whereas T cell immunity was increased in chimeric mice with NGAL-deficient neutrophils with more

286 infarct sizes and fibrin(ogen) deposition in chimeric mice with only platelet VWF were significantly

287 Chimeric mice with P2y2 deficiency restricted to hematop

288 Upon BDL, chimeric mice with p47phox KO BM-derived cells, includin

289 intersectional genetics to create temporally chimeric mice with SCN containing dopamine 1a receptor (

290 inferior vena cava, APP-KO mice, as well as chimeric mice with selective deficiency of APP in blood

291 henotype was reproduced by mixed bone marrow chimeric mice with Sema4C deficient only in B cells, ind

292 Furthermore, WT chimeric mice with transplanted p38gamma/delta(-/-) bone

293 Chimeric mice with USP21-deficient hematopoietic cells d

294 Chimeric mice with VWF present only in platelets were no

295 Chimeric mice with wild-type CNS cells and Ccr2(-/-) hem

296 oximately 25% reduction of fibrosis, whereas chimeric mice with WT BM-derived cells and p47phox KO en

297 gnificantly increased in p38gamma/delta(-/-) chimeric mice with WT bone marrow compared with p38gamma

298 ografts is achieved in CD117-ADC-conditioned chimeric mice without chronic immunosuppression.

299 neration of genetically defined multiallelic chimeric mice without further strain intercrossing.

300 WKYMVm-induced leukocyte recruitment in chimeric mice (WT bone marrow to Fer(DR/DR) recipients o