ライフサイエンスコーパス: chitinase

1 ilA (transformation pseudopilus) and chiA-1 (chitinase).

2 tial mixotrophic goal (i.e. exoproteases and chitinases).

3 ding 12 proteases, two phospholipases, and a chitinase.

4 differences were noted in plasma for either chitinase.

5 pendent of the chitinolytic activity of this chitinase.

6 can be negatively regulated by a vertebrate chitinase.

7 nel of strains where each expresses a single chitinase.

8 efense response, namely the effects of wheat chitinases.

9 tion of pathogenesis-related genes including chitinases.

10 erences in processivity of the S. marcescens chitinases.

11 to degrade chitin analogs and produce active chitinases.

12 hin a sequence that is conserved in class IV chitinases.

13 and transgenic expression of plant class IV chitinases.

14 olutionary paths for human and monkey acidic chitinases.

15 recycled by ubiquitous bacterial and fungal chitinases.

16 x1 in infection and in protection from wheat chitinases.

17 Of the differentially expressed genes, chitinase 1 (CHIT1) and cytochrome P450 family 1 subfami

18 Chitinase 1 (CHIT1) is secreted by activated macrophages

19 ificant reduction in the expression level of chitinase 1 and caused abortive molting in the insects.

20 ons in the genes CG6479, separation anxiety, chitinase 11, CG6364 (Uck2), CG6543 (Echs1), withered (w

21 egression protein-39 (BRP-39), also known as chitinase 3-like 1 (CHI3L1) and encoded by the Chi3l1 ge

22 ingle nucleotide polymorphisms (SNPs) in the chitinase 3-like 1 (CHI3L1) gene or its promoter.

23 Chitinase 3-like 1 (CHI3L1) has been shown to play a rol

24 ingle nucleotide polymorphisms (SNPs) in the chitinase 3-like 1 (CHI3L1) promoter, the gene encoding

25 One of Stat3 downstream genes products, chitinase 3-like 1 (CHI3L1) protein, showed increased co

26 In vivo and in vitro studies reveal chitinase 3-like 1 (Chi3l1) to be a major target and eff

27 Chitinase 3-like 1 (CHI3L1), also known as breast regres

28 d by genetic variation in its encoding gene (chitinase 3-like 1 [CHI3L1]) and are increased in patien

29 A promoter SNP (-131C-->G) in CHI3L1, the chitinase 3-like 1 gene encoding YKL-40, was associated

30 in Brp-39, the murine protein product of the chitinase 3-like 1 gene, as a critical component of this

31 Recently, a role of the chitinase 3-like 1 protein (YKL-40) has been evoked in a

32 The CLPs BRP-39/YKL-40 (also termed chitinase 3-like 1) inhibit oxidant-induced lung injury,

33 e wound tissue expressed high levels of Ym1 (chitinase 3-like 3), an established marker of the IL-4-i

34 Promoters from the chitinase 3-like 3, Wnt inhibitory factor 1, and fms-rel

35 eta and TNFalpha caused increased release of chitinase 3-like protein 1 (CHI3L1), CHI3L2, complement

36 s of inflammatory (C-Reactive Protein [CRP], Chitinase 3-like protein-1 [CHI3L1], Interleukin 18 Bind

37 mediated by an N-glycosylated asparagine in chitinase 3-like-1 (amino acid 68) on IECs.

38 Recent studies demonstrated that chitinase 3-like-1 (Chi3l1) binds to and signals via IL-

39 Chitinase 3-like-1 (Chi3l1) is an evolutionarily conserv

40 The prototypic chitinase-like protein chitinase 3-like-1 (CHI3L1) plays a protective role in t

41 We determined that Chitinase 3-like-1 (Chi3l1), a conserved prototypic chit

42 Chitinase 3-like-1 (CHI3L1/YKL-40) is a protein secreted

43 Chitinase 3-like-1 (Chil1) is expressed during infection

44 rils via the TGF-beta1 signaling pathway and chitinase 3-like-1 activity in fibroblasts in lymphoid t

45 Inducible chitinase 3-like-1 is expressed by intestinal epithelial

46 AIEC adheres to an N-glycosylated chitinase 3-like-1 on IECs via the chitin-binding domain

47 indicated by increases in the expression of Chitinase 3-Like-1, and the colorectal cancer metastasis

48 s that comprised matrix metalloproteinase 9, chitinase 3-like-1, S100 calcium binding protein A8 (S10

49 Here, we demonstrate that murine Chitinase 3-like-3 (Chi3l3/Ym1), human Chi3L1 and Chit1

50 teomic analysis revealed decreased levels of chitinase-3-like 3 and accumulation of the receptor for

51 rease 2.53), agouti-related protein; (1.48), chitinase-3-like protein 1 (1.35), C-C motif chemokine 2

52 a-related proteins, chitotriosidase (CHIT1), chitinase-3-like protein 1 (CHI3L1 or YKL-40), and solub

53 We investigated the effect of chitinase-3-like protein 1 (CHI3L1) on glucose metabolis

54 ER cells, including androgen receptor (AR), chitinase-3-like protein 1 (CHI3L1), and IFN-stimulated

55 Chitinase-3-like protein 1 (CHI3L1), C-reactive protein

56 , we quantified chitotriosidase (Chit-1) and chitinase-3-like protein 1 (CHI3L1), markers of glial ac

57 u181), visinin-like protein 1 (VILIP-1), and chitinase-3-like protein 1 (YKL-40).

58 YKL-40 (chitinase-3-like protein 1), a protein involved in ather

59 utoimmunity, such as soluble CD163 (sCD163), chitinase-3-like protein 1, osteopontin, and pentraxin-3

60 lls [sTREM-1], interleukin-6, interleukin-8, chitinase-3-like protein-1, soluble tumor necrosis facto

61 arkers of inflammation including crystals of chitinase-3-like proteins.

62 secretion of matrix metalloproteinase 9 and chitinase-3-like-1 protein but differentially affected t

63 ound in inflammatory zone-1, arginase-1, and chitinase-3-like-3.

64 nes and helped identify genes (e.g. Tomosyn, Chitinase 5, Adar, Innexin 2, Transferrin 1, Sick, Oatp2

65 that might function with dyl and identified Chitinase 6 (Cht6) as a strong candidate, as knocking do

66 ontrols the expression of the promoter for a chitinase, a type VI secretion-related gene, a transcrip

67 Instead, the new cuticle is protected from chitinase action by the T. castaneum Knickkopf (TcKnk) p

68 Patients with CF have enhanced chitinase activation associated with C albicans coloniza

69 the export of protease, phospholipase C, and chitinase activities is T2SS dependent.

70 molecular basis to explain the differential chitinase activities observed among the species and subp

71 bacteria compared with nonpathogenic E coli; chitinase activities were measured using the colloidal c

72 gher gene regulation and beta-1,3-glucanase, chitinase activities were observed in cv. Ryan compared

73 Chitinase activities were quantified in serum and bronch

74 A, ChiB, ChiC, and ChiD possessed dissimilar chitinase activities.

75 as well as alkaline phosphatase, lipase and chitinase activities.

76 iae sprE resulted in decreased extracellular chitinase activity and decreased secretion of the cell s

77 tics, asthmatic children exhibited increased chitinase activity and increased YKL-40 levels in BALF.

78 Transformants expressing tri5 displayed low chitinase activity and induced expression of Botrytis ci

79 BALF was tested for chitinase activity and YKL-40 (an enzymatically inactive

80 h this analysis, we found that low levels of chitinase activity are sufficient for natural transforma

81 t pH profile exhibiting greater retention of chitinase activity at acidic and basic pH values.

82 which is ameliorated by restoration of lung chitinase activity by genetic or therapeutic approaches.

83 In addition, the overall level of chitinase activity differed among the subpopulations of

84 ave shown the importance of acidic mammalian chitinase activity in settings of chitin exposure and al

85 Chitinase activity is raised in atherosclerotic patient

86 ogen content correlated positively with high chitinase activity of ectomycorrhizas.

87 ssociated with whole-cell lysates, while the chitinase activity of F. novicida localized to the cultu

88 The aim of this study was to assess chitinase activity systemically and in the airways of pa

89 Further stratification showed that chitinase activity was enhanced in patients with CF colo

90 Chitinase activity was greater in the BALF of asthmatics

91 Chitinase activity was systemically increased in patient

92 itionally, we assessed factors that regulate chitinase activity within the lungs of patients with CF.

93 ead, we show that an rpoS mutant has reduced chitinase activity, which is required to liberate the so

94 n the BALF of asthmatics and correlated with chitinase activity.

95 YKL-40 are chitinase-like proteins that lack chitinase activity.

96 on source requires more robust and concerted chitinase activity.

97 inase (AMCase), which is required for airway chitinase activity.

98 Three of the chitinases also hydrolyzed the beta1-6 bond in LacNAcbet

99 were digested with stomach acidic mammalian chitinase (AMC), their size-dependent macrophage activat

100 Acidic mammalian chitinase (AMCase) and chitotriosidase-1 (CHIT1) are two

101 Chitotriosidase (CHIT1) and acidic mammalian chitinase (AMCase) are the enzymatically active chitinas

102 e, we provide evidence that acidic mammalian chitinase (AMCase) can function as a major digestive enz

103 Acidic mammalian chitinase (AMCase) inhibits chitin-induced innate inflam

104 Acidic mammalian chitinase (AMCase) is a member of the glycosyl hydrolase

105 Acidic mammalian chitinase (AMCase) is expressed in an exaggerated fashio

106 Acidic mammalian chitinase (AMCase) is known to be induced by allergens a

107 Acidic mammalian chitinase (AMCase) is produced during and plays an impor

108 Acidic mammalian chitinase (AMCase), an enzyme implicated in the patholog

109 g an enzymatically inactive acidic mammalian chitinase (AMCase), the dominant true chitinase in mouse

110 ng epithelial cells secrete acidic mammalian chitinase (AMCase), which is required for airway chitina

111 with the IL-4- and IL-13-inducible mammalian chitinase, AMCase, or if the chitin was injected into mi

112 a potent and specific inhibitor of filarial chitinases, an activity not previously reported for this

113 s significantly suppressed for activities of chitinase and beta-1,3-glucanase at pH 5 and 7, consiste

114 Chitinase and digestive protease transcript expression l

115 inhibitions of molt-related proteins such as chitinase and JHE-carboxylesterase.

116 dation by full-length Jd1381 depended on its chitinase and LPMO activities.

117 Both the chitinase and the LPMO activities of Jd1381 were similar

118 the activities of combinations of well-known chitinases and an LPMO from Serratia marcescens Importan

119 hat were required for secretion of all three chitinases and Cbp21.

120 It is becoming increasingly apparent that chitinases and chilectins play an important role in infl

121 he absence of endogenous chitin, a number of chitinases and chitinase-like proteins (C/CLPs) have bee

122 tin- and chitosan-modifying enzymes, such as chitinases and chitosanases, with known and defined subs

123 elated (PR) genes, such as of PR10 homologs, chitinases and defense-related transcription factors, su

124 Recombinant production of the putative chitinases and enzymatic evaluations revealed ChiA, ChiB

125 e created a strain that lacks all 7 putative chitinases and from this strain, generated a panel of st

126 sing evidence highlights the contribution of chitinases and fungal infection to the development of as

127 81 were similar to those of other individual chitinases and LPMOs, and the overall efficiency of chit

128 number of antimicrobial proteins, including chitinases and pathogenesis-related proteins.

129 chanism accounts for the selective action of chitinases and possibly other molting enzymes.

130 enesis-related genes, such as genes encoding chitinases and PR1, are upregulated in both the SA-defic

131 , and not CHIA, is a gene encoding an acidic chitinase, and cloned it, using the sequence of human CH

132 ng motility apparatus and for secretion of a chitinase, and the P. gingivalis PorSS is involved in se

133 hrough the airway epithelium inhibits mucus, chitinases, and eosinophilia, independent of Th2 cell ac

134 ium-binding site not previously seen in GH18 chitinases, and, importantly, a displaced catalytic acid

135 duction of rhizoxin analogs, orfamide A, and chitinase are required for full oral toxicity of Pf-5 ag

136 Plant chitinases are an example of food allergenic proteins fo

137 Chitinases are enzymes that cleave chitin, a component o

138 Chitinases are enzymes that hydrolyze chitin, a polymer

139 some isoforms of thaumatin-like proteins and chitinases are involved in haze formation.

140 e phylogenetically related to the Salmonella chitinase, as well as unrelated chitinases from Listeria

141 pathogenesis-related genes such as PR1b1 and chitinase B compared with the wild-type.

142 sion of the ethylene-responsive genes E4 and chitinase B was upregulated in transgenic plants, but et

143 ed activity of defence related enzymes, i.e. chitinase, beta-1,3-glucanase and PAL, and higher conten

144 Additional proteins, globulin 3A and 3C, chitinase, beta-amylase and LMW glutenins, were identifi

145 tures suggest additional functional roles of chitinases beyond chitin hydrolysis.

146 ned the binding affinities of the Salmonella chitinase by carbohydrate microarray screening and found

147 , whereas those of aryl acylamidase (AA) and chitinase (CHI) increased during the initial period and

148 hitin-binding domain (CBM5), and a family 18 chitinase (Chi18) domain.

149 t resistance genes from C. platycarpus viz., chitinase (CHI4), Alpha-amylase/subtilisin inhibitor (IA

150 d was applied to the study of the processive chitinase ChiA from Serratia marcescens.

151 drolase Cel7A from Hypocrea jecorina and the chitinase ChiA from Serratia marcescens.

152 face motility adhesins SprB and RemA and the chitinase ChiA.

153 cular dynamics simulations of two processive chitinases (ChiA and ChiB), the ChiC catalytic module, a

154 olific secretor of proteins, including three chitinases (ChiA, ChiB, and ChiC) and a chitin binding p

155 that cdGMP stimulated the transcription of a chitinase (ChiB) known to contribute to biofilm formatio

156 l pathogens that truncate the plant class IV chitinases ChitA and ChitB during maize ear rot.

157 g these carbohydrate-active enzymes, such as chitinases, chitobiases, and lytic polysaccharide monoox

158 that the T2SS releases chitinolytic enzymes (chitinase, chitosanase) and chitin-binding proteins.

159 Pathogenesis-related proteins, chitinases (CHT) and beta-1,3-glucanases (GLU), are stre

160 tivity and YKL-40 (an enzymatically inactive chitinase) concentrations.

161 All chitinases correlated with pNFH.

162 he improvement of transglycosylation (TG) by chitinase D from Serratia proteamaculans (SpChiD).

163 the role of CF airway proteases and genetic chitinase deficiency was assessed.

164 Genetic chitinase deficiency was associated with C albicans colo

165 ectopically express all 7 chitinases in our chitinase deficient strain.

166 SnTox1 protected the different fungi from chitinase degradation.

167 ic, of low molecular weight and resistant to chitinase degradation.

168 These chitinase degraded products and by-products can be used

169 The HPLC analysis of chitinase degraded shellfish waste reveals a major amino

170 Knickkopf protects chitin from chitinase-dependent degradation and deacetylase enzymes

171 Down-regulation of TcKnk results in chitinase-dependent loss of chitin, severe molting defec

172 uorescent material to chitin was verified by chitinase digestion.

173 ndoS confirmed the previous predictions of a chitinase domain and leucine-rich repeat but also reveal

174 an N-terminal peroxiredoxin and a C-terminal chitinase domain.

175 m fulvum, to shield chitin from host-derived chitinases during infection.

176 is showed that this protein does not possess chitinase enzymatic activity.

177 e still lack an economical and highly stable chitinase enzyme for use in the industrial sector.

178 Chitinase enzymes hydrolyse the polysaccharide chitin, a

179 quential catalysis, using crude protease and chitinase enzymes immobilized on agar beads.

180 We found that all chitinases examined hydrolyzed LacdiNAc from the TMR agl

181 he purpose of this study was to characterize chitinase expression and serological markers of fungal i

182 d, while YM2 expression and acidic mammalian chitinase expression were decreased.

183 ation and was decreased by constitutive lung chitinase expression.

184 icate functional specialization among insect chitinase family genes, primarily during the molting pro

185 e glycoprotein YKL-40 (CHI3L1) is a secreted chitinase family protein that induces angiogenesis, cell

186 stent with innate host defense traits of the chitinase family.

187 wn that both the human chitotriosidase and a chitinase from Salmonella enterica serovar Typhimurium h

188 This chitinase from the A. xylosoxidans was 100% active at an

189 Although vertebrates express active chitinases from evolutionarily conserved loci, their rol

190 In this study, we identified two plant chitinases from fall armyworm (Spodoptera frugiperda) la

191 e Salmonella chitinase, as well as unrelated chitinases from Listeria monocytogenes using the fluores

192 he hydrolytic specificity of this enzyme and chitinases from Sodalis glossinidius and Polysphondylium

193 machinery, including hemagglutinin protease, chitinase, GbpA, and lipase.

194 The chitinase gene clusters and NBS-LRR disease resistance g

195 ibutable to the expanded cytochrome P450 and chitinase gene families.

196 ormatic analyses identified two new putative chitinase genes (chiC and chiD), as well as the previous

197 Two chitinase genes (CTS2 and CTS3) were disrupted to yield

198 obacteriaceae in the root endosphere and for chitinase genes and various unknown biosynthetic gene cl

199 he expression of both beta-1,3-glucanase and chitinase genes in naturally infected fruit of both cult

200 However, defense-related proteins such as chitinases, glucanases, myrosinases, and others showed e

201 Chitinase (HaCHI) gene, critically required for insect m

202 ngs and animal model studies, involvement of chitinases has been suggested in several respiratory sys

203 There is emerging evidence that chitinases have additional functions beyond degrading en

204 Chitinases have recently gained attention in the field o

205 In conclusion, a class IV chitinase HrCHI4 was purified from seabuckthorn seeds an

206 Here, ~39 kDa class IV chitinase (HrCHI4) was purified from seabuckthorn seeds

207 SS is involved in secretion of extracellular chitinase in addition to its role in secretion of SprB.

208 These results demonstrated the role of chitinase in insect development and potential of HI-RNAi

209 malian chitinase (AMCase), the dominant true chitinase in mouse lung, showed enhanced type 2 immune r

210 an increase in the processing of a class IV chitinase in planta.

211 ssing constitutively active acidic mammalian chitinase in the lungs demonstrated a significant reduct

212 s are consistent with and suggest a role for chitinases in asthma pathogenesis among Bronx children a

213 ession plasmids to ectopically express all 7 chitinases in our chitinase deficient strain.

214 CF proteases degraded chitinases in the airway microenvironment of patients wi

215 rgic inflammation in the lung, and mammalian chitinases, including acidic mammalian chitinase, limit

216 ata, unexpected synergistic protonophore and chitinase inhibition activities have also been found to

217 Conversely, chitinase inhibition prolonged the duration of tissue eo

218 increased, Arg1 expression was decreased by chitinase inhibition, suggesting that suppression of CHI

219 structural elements critical for closantel's chitinase inhibitor function.

220 Thus, we investigated the effects of a chitinase inhibitor, allosamidin, on macrophage function

221 d, compounds acting only as protonophores or chitinase inhibitors were identified.

222 suited for the high-throughput screening of chitinase inhibitors.

223 educed when compared to the earlier reported chitinase inhibitors.

224 d in phytoalexin synthesis, chitinaseb1-1, a chitinase involved in pathogen defense, and Glycine max

225 and microscopic investigations we found that chitinase is essential for bacteria to enter hyphae.

226 indicates that Plasmodium ookinete-secreted chitinase is important in midgut invasion.

227 The 18 glycosyl hydrolase family of chitinases is an ancient gene family that is widely expr

228 nalogs, the enzyme mechanism of the class IV chitinases is described for the first time.

229 Chitinase levels were longitudinally stable.

230 Chitinase levels were similar in AGCs and healthy contro

231 recruitment, and elevated KC, TNF-alpha, and chitinase levels.

232 We show that the chitinase-like (CTL) proteins, CTL1/POM1 and CTL2, are f

233 L6) along with the M2 markers arginase-1 and chitinase-like 3 (Chil3 or YM1) were evaluated by real t

234 n of Relm-alpha, without similarly affecting Chitinase-like 3 (Chil3/Ym1).

235 germ-free mice, but neutralization of Ym1, a chitinase-like molecule that is associated with alternat

236 are defined by the expression of Arginase 1, chitinase-like molecules, and resistin-like molecule (RE

237 mice, we identified the macrophage-secreted chitinase-like protein Brp-39, the murine protein produc

238 The prototypic chitinase-like protein Chi3l1 is induced in cancers and

239 The prototypic chitinase-like protein chitinase 3-like-1 (CHI3L1) plays

240 disc growth factor 2 (IDGF2) is a member of chitinase-like protein family (CLPs) able to induce the

241 Circulating levels of the chitinase-like protein YKL-40 are influenced by genetic

242 The chitinase-like protein YKL-40 has been related to asthma

243 The chitinase-like protein YKL-40 is involved in inflammatio

244 The chitinase-like protein YKL-40, encoded by the CHI3L1 gen

245 se 3-like-1 (Chi3l1), a conserved prototypic chitinase-like protein, is induced by Streptococcus pneu

246 A third chitinase-like protein, TcCHT7, was required for abdomin

247 A fourth chitinase-like protein, TcIDGF4, exhibited no chitinolyt

248 ndogenous chitin, a number of chitinases and chitinase-like proteins (C/CLPs) have been identified.

249 Although chitinase-like proteins (CLPs) form part of this microen

250 Enzymatically inactive chitinase-like proteins (CLPs) such as BRP-39, Ym1 and Y

251 Chitinase-like proteins are associated with type 2 immun

252 of individual members of the large family of chitinase-like proteins from the red flour beetle, Tribo

253 expression of IL-1beta, IL-6, TNF-alpha, and chitinase-like proteins in whole lung.

254 l homologues encoding catalytically inactive chitinase-like proteins or chilectins (all GH18 family p

255 ; Chi3l1) and its human homologue YKL-40 are chitinase-like proteins that lack chitinase activity.

256 r knockdown of transcripts for several other chitinase-like proteins, including imaginal disk growth

257 le for the presence of a large assortment of chitinase-like proteins.

258 Ym1/Ym2 is a chitinase-like secretory protein that is transiently ind

259 didate gene responsible for bk4 phenotype is Chitinase-like1 protein (Ctl1), which is expressed at it

260 alian chitinases, including acidic mammalian chitinase, limit this process.

261 These plant chitinases mediate the suppression of herbivore-induced

262 Therefore chitinases might represent a novel biomarker and therape

263 Chitinase-modifying proteins (cmps) are proteases secret

264 This substrate specificity was evident for chitinases of different phylogenetic origins.

265 Importantly, the chitinase OvCHT1 from O. volvulus was recently discovere

266 The L3-stage-specific chitinase OvCHT1 has been implicated in the development

267 osed evidence that the larval-stage-specific chitinase, OvCHT1, may be a potential biological target

268 inine biosynthesis and positive selection on chitinase pathways.

269 lactosidase, beta-glucosidase, beta-amylase, chitinase, pectate lyase (PL), pectinesterase (PE) and p

270 the P. gallinaceum ortholog of P. falciparum chitinase PfCHT1) are both localized on the ookinete api

271 defenses by deposition of the plant-derived chitinases Pr4 and Endochitinase A is a unique way an in

272 Our study shows that maize chitinases, Pr4 and Endochitinase A, are induced during

273 ll-length enzyme, which seems to be the only chitinase produced by J. denitrificans, degraded both al

274 Many marine microbial strains have chitinase producing ability.

275 ulture conditions were optimised for maximum chitinase production recording up to 467 U/ml.

276 ition optimisation predicted a 464.2 U/ml of chitinase production.

277 Chitinase proteins distinguished ALS from healthy contro

278 CSF chitinase proteins may have limited value as independent

279 The recombinant maize chitinase, rChiA, was purified from Pichia pastoris extr

280 t mutation in the AtCTL1 gene that encodes a chitinase-related protein, although molecular and bioche

281 ndicate that ChiA is a soluble extracellular chitinase required for chitin utilization and that it re

282 ct chitin in fungal cell walls against plant chitinases, respectively.

283 SprF was not needed for chitinase secretion and may be specifically required for

284 n of the entire chitinolytic machinery, with chitinase secretion being blocked at a late stage in the

285 For instance, the chitinase secretion pathway of Serratia marcescens uses

286 egion had a cluster of genes, which code for chitinases, strictosidine synthase-like, and NBS-LRR pro

287 tection against plant- and microbial-derived chitinases, suggesting a broader role beyond deregulatio

288 pecific knockdown of transcripts for another chitinase, TcCHT10, which has multiple catalytic domains

289 One chitinase, TcCHT5, was found to be required for pupal-ad

290 ate-binding proteins) that crosslink chitin, chitinases that degrade chitin, and Jessie lectins that

291 tinase (AMCase) are the enzymatically active chitinases that have been implicated in the pathology of

292 rived from antibodies specific to a parasite chitinase, the 25 kDa protein and the circumsporozoite p

293 sed from the cell wall as elicitors by human chitinases, thus making the fungus less susceptible to h

294 e named the new enzyme MACase (Macaca Acidic Chitinase) to emphasize its differences from AMCase.

295 Immobilized protease and chitinase treatment improved CS yields (101 mug/ml) and

296 yield for protease were 84% and 62%, and for chitinase were 75% and 57%, respectively.

297 , enhanced activities of beta-1,3-glucanase, chitinase were noted in both cultivars.

298 Five potential chitinases were identified by genome analysis.

299 The molting fluid enzyme chitinase, which degrades the matrix polysaccharide chit

300 Chitin utilization requires chitinases, which degrade this insoluble polymer into so