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1 were analyzed (164 soap and water versus 161 chlorhexidine).
2 ggested a lack of resistance to mupirocin or chlorhexidine.
3 se the ocular safety and efficacy of aqueous chlorhexidine.
4 aily bathing of critically ill patients with chlorhexidine.
5 ents (9.6%) met the definition of allergy to chlorhexidine.
6 athogens than did clinical concentrations of chlorhexidine.
7 actions, 9.6% were diagnosed with allergy to chlorhexidine.
8 acter baylyi rendered it more susceptible to chlorhexidine.
9 t and specific interactions between AceI and chlorhexidine.
10 stance and transport, was still able to bind chlorhexidine.
11 le to mediate the energy-dependent efflux of chlorhexidine.
12 ed in significant increases in resistance to chlorhexidine.
13 rred in 7 patients, were mild and related to chlorhexidine.
14 matitis rate was 1.1% with and 0.29% without chlorhexidine.
15 to compare antiplaque efficacy in vivo with chlorhexidine.
16 reased after oral rinsing with antibacterial chlorhexidine.
17 cally active: clotrimazole, flunarizine, and chlorhexidine.
18 mvR also have an increased susceptibility to chlorhexidine.
19 nal specialists who exclusively used aqueous chlorhexidine 0.05% or 0.1% for prophylaxis of infective
20 d panel; many failed to screen all cases for chlorhexidine 19/44 (43%) or latex 21/44 (48%)], staffin
21 contaminated disks were burnished with 0.12% chlorhexidine, 20% citric acid, 24% EDTA/1.5% NaOCl, or
22 he following: NMBA (35%), antibiotics (46%), chlorhexidine (8%), patent blue dye (8%) and others (8%)
23 ional coating on titanium surfaces releasing chlorhexidine, a well-known antimicrobial agent used in
28 omparing iodine povacrylex-alcohol (IPA) and chlorhexidine-alcohol for elective, clean-contaminated c
30 olled trial, we evaluated whether the use of chlorhexidine-alcohol for preoperative skin antisepsis w
31 cial surgical-site infection was 3.0% in the chlorhexidine-alcohol group and 4.9% in the iodine-alcoh
33 n was diagnosed in 23 patients (4.0%) in the chlorhexidine-alcohol group and in 42 (7.3%) in the iodi
34 ite infection was significantly lower in the chlorhexidine-alcohol group than in the povidone-iodine
35 esized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infecti
37 to preoperative skin preparation with either chlorhexidine-alcohol scrub or povidone-iodine scrub and
41 aims were to estimate (i) the prevalence of chlorhexidine allergy in perioperative allergy and (ii)
45 were 25 (<1%) adverse events, all involving chlorhexidine, among 183 013 patients in units assigned
47 th the sole characterized substrate of AceI, chlorhexidine, an entirely synthetic biocide produced on
48 te was 2.86 per 1000 patient-days during the chlorhexidine and 2.90 per 1000 patient-days during the
54 n, and decolonisation of MRSA carriers) with chlorhexidine and mupirocin, and universal decolonisatio
55 decolonization, targeted decolonization with chlorhexidine and mupirocin, or universal decolonization
59 most common skin preparation wipes (alcohol, chlorhexidine and povidone iodine) and found that during
61 e further discovered the target of action of chlorhexidine and show that it is a selective inhibitor
63 bacteria, and Candida were cultured from the chlorhexidine and silver sulfadiazine central venous cat
64 ated with 5-fluorouracil were noninferior to chlorhexidine and silver sulfadiazine coated central ven
66 ernative to catheters externally coated with chlorhexidine and silver sulfadiazine when used in criti
67 ine bathing to decolonisation with universal chlorhexidine and targeted nasal mupirocin in non-critic
68 t that boric acid could be an alternative to chlorhexidine, and it might be more favorable because bo
69 lorhexidine mouthwash, baths or showers with chlorhexidine, and nasal mupirocin for 5 days twice per
71 oral bacteria and compare the same with 0.2% chlorhexidine; and 2) to compare antiplaque efficacy in
82 onization-treatment of all ICU patients with chlorhexidine bathing and nasal mupirocin-used a prerele
87 its assigned to either routine care or daily chlorhexidine bathing for all patients plus mupirocin fo
88 E Infection trial was to evaluate the use of chlorhexidine bathing in non-critical-care units, with a
91 on was 5.10 cases per 1000 patient-days with chlorhexidine bathing versus 6.60 cases per 1000 patient
92 ns was 4.78 cases per 1000 patient-days with chlorhexidine bathing versus 6.60 cases per 1000 patient
93 n, 2) chlorhexidine oral hygiene program, 3) chlorhexidine bathing, 4) catheter-associated bloodstrea
94 control practices (ie, active surveillance, chlorhexidine bathing, decolonization for MRSA, and hydr
96 high level of compliance to hand hygiene and chlorhexidine bathings, screening and isolation of carri
97 unty, California, we evaluated the impact of chlorhexidine baths and mupirocin on all ICU admissions
98 ation of patients in the ICU with once a day chlorhexidine baths and short-course nasal mupirocin cou
99 ation measures, including once-weekly use of chlorhexidine body wash, did not prevent overall SSTI or
102 nasal carriers with mupirocin together with chlorhexidine body washing reduces the incidence of S. a
103 n interrupted time series study of universal chlorhexidine body-washing combined with hand hygiene im
104 Median proportions of patients receiving chlorhexidine body-washing increased from 0% to 100% at
106 moniae has previously been shown to adapt to chlorhexidine by increasing expression of the MFS efflux
107 ed with blood culture kits containing either chlorhexidine (CH) or iodine tincture (IT) for skin anti
111 d bi-weekly supragingival plaque removal and chlorhexidine chips application (ChxC group) for 12 week
112 ival plaque removal and local application of chlorhexidine chips had greater mean IPD reduction and g
113 n protocols (12 S/R per group): 24% EDTA, 2% chlorhexidine (CHL), gauze soaked in 2% chlorhexidine (G
114 nd antibiofilm efficiency were compared with chlorhexidine (CHX) and sodium hypochlorite (NaOCl).
115 s, the systemic use of azithromycin (AZ) and chlorhexidine (CHX) as adjuvants to non-surgical periodo
116 sites releasing antibacterial agents such as chlorhexidine (CHX) have shown biofilm-inhibitory effica
117 this study is to determine the influence of chlorhexidine (CHX) intracanal medicament on the clinica
119 n we investigated the effect of 7-day use of chlorhexidine (CHX) mouthwash on the salivary microbiome
121 bstantivity of a single mouthrinse with 0.2% chlorhexidine (CHX) on saliva and on undisturbed de novo
122 olution (10(9) beads/mL) and, second, a 0.2% chlorhexidine (CHX) or 0.085% cetylpyridinium chloride (
123 available mouthwashes that contained either chlorhexidine (CHX) or essential oils (EO) as the active
124 t was suggested that periodontal therapy and chlorhexidine (CHX) rinse could affect nitrite levels, l
125 lication of local chemical adjuncts, such as chlorhexidine (CHX), have been used to control and treat
126 ecause standard adjuvant antiseptics, namely chlorhexidine (CHX), prove damaging for osteoblasts.
127 : povidone-iodine (PovI; 0.05%, 1%, and 5%), chlorhexidine (CHX; 0.2% and 1%), and sodium hypochlorit
129 c defined as a relevant clinical reaction to chlorhexidine combined with two or more positive tests.
130 eductions previously reported in south Asia, chlorhexidine cord applications did not significantly re
132 r patients bathed with soap and water versus chlorhexidine, counts of incident hospital-acquired infe
133 in the units: chlorhexidine "scrub-the-hub," chlorhexidine daily baths, and daily nursing rounds aime
136 ions at screening) to test the efficacy of a chlorhexidine diacetate 10% weight per volume (w/v) dent
138 In this pragmatic trial, daily bathing with chlorhexidine did not reduce the incidence of health car
139 onic antifungal drugs such as miconazole and chlorhexidine digluconate (CG) through ionic interaction
140 ence rate, 80% [12 of 15 isolates]) than for chlorhexidine digluconate (median growth grade, 1.0; kil
141 whether polyhexamethylene biguanide, 0.02%, chlorhexidine digluconate, 0.02%, hexamidine diisethioon
142 -mouth SRP using 0.9% sodium chloride, 0.12% chlorhexidine digluconate, or 7.5% povidone-iodine for s
143 ensive local antiseptic interventions with a chlorhexidine disc and hypochlorite solution reduce bact
146 hours or more in 12 French ICUs, we compared chlorhexidine dressings, highly adhesive dressings, and
148 ata are consistent with AceI being an active chlorhexidine efflux protein and the founding member of
149 protein of this family, AceI (Acinetobacter chlorhexidine efflux protein I), is encoded for by the a
150 anscriptional control of AceR (Acinetobacter chlorhexidine efflux protein regulator), a LysR-type tra
151 Patients were randomized to bathing with 2% chlorhexidine every other day alternating with soap and
152 forms dimers at high pH, and that binding to chlorhexidine facilitates the functional form of the pro
153 LTP3-plasma treatment for 3 minute, CHX-0.2% chlorhexidine for 1 minute, GAS-gas only (no plasma) for
154 nts were randomly assigned to either 4% free chlorhexidine for cord care or to dry cord care using a
157 to two topical microbiocides, mupirocin and chlorhexidine, frequently used for decolonization and in
159 , 2% chlorhexidine (CHL), gauze soaked in 2% chlorhexidine (GCHL), gauze soaked in ultrapure water (G
160 e, consisting of head-of-bed elevation, oral chlorhexidine gel, sedation holds, and a weaning protoco
161 A large randomized trial demonstrated that chlorhexidine-gel-impregnated dressings decreased the CR
162 by repetitive intraperitoneal injections of chlorhexidine gluconate (CG) in mice with type I pro-col
163 ution of peritoneal MCs to myofibroblasts in chlorhexidine gluconate (CG)-induced fibrosis compared w
164 e collected and tested for susceptibility to chlorhexidine gluconate (CHG) by microtiter dilution; mu
165 ctive was to assess whether daily bathing in chlorhexidine gluconate (CHG) compared with standard bat
166 very of multispecies oral biofilms following chlorhexidine gluconate (CHX) and CHX with surface modif
167 films is investigated following treatment by chlorhexidine gluconate (CHX), iodine-potassium iodide (
168 is study compared the safety and efficacy of chlorhexidine gluconate 2.5 mg chip (CHX chips) as an ad
170 ze antiseptic skin surface concentrations of chlorhexidine gluconate applied during preoperative show
171 Other intervention components such as daily chlorhexidine gluconate bathing of all patients and hand
172 s; geographic and personnel cohorting; daily chlorhexidine gluconate baths; dedicating equipment to b
174 ion have assessed the safety and efficacy of chlorhexidine gluconate for cutaneous antisepsis and sil
176 the use of an ultrasonic unit, and that 0.2% chlorhexidine gluconate is more effective than herbal mo
178 surface (16.5 microg/cm2) concentrations of chlorhexidine gluconate that are sufficient to inhibit o
180 preoperative decontamination protocol using chlorhexidine gluconate washcloths and intranasal antise
183 ower regimen that includes 118 mL of aqueous chlorhexidine gluconate, 4%, per shower; a minimum of 2
184 r administering the preadmission shower with chlorhexidine gluconate, 4%, resulting in maximal, persi
187 is by delineating a precise dose (volume) of chlorhexidine gluconate, 4%; duration (number of showers
188 le preprocedural mouthrinses containing 0.2% chlorhexidine gluconate, an herbal mouthwash, and water
189 nd C) of eight patients each to receive 0.2% chlorhexidine gluconate, herbal mouthwash, and water, re
190 nhibitory effects of three test agents, 0.2% chlorhexidine gluconate, honey mouthwash, and saline, ag
192 lesions resolved with discontinuation of the chlorhexidine gluconate-containing dressings, local woun
194 e phenotypic range of this adverse effect of chlorhexidine gluconate-impregnated dressings in critica
196 f erosive irritant contact dermatitis due to chlorhexidine gluconate-impregnated transparent dressing
200 ingle rooms; bathing all patients daily with chlorhexidine gluconate; and healthcare-worker education
202 ily for up to 5 days and to bathe daily with chlorhexidine-gluconate (CHG) for up to 5 days before th
203 r (standard group), a standard catheter plus chlorhexidine-gluconate-impregnated sponge (chlorhexidin
204 chlorhexidine-gluconate-impregnated sponge (chlorhexidine-gluconate-impregnated sponge group), or an
205 ients, 156 in the standard-group, 150 in the chlorhexidine-gluconate-impregnated sponge group, and 15
206 (15.4%) standard catheters, 21 (14%) in the chlorhexidine-gluconate-impregnated sponge group, and 25
207 e (5.8%) standard catheters, six (4%) in the chlorhexidine-gluconate-impregnated sponge group, and se
209 rence in neonatal mortality rate between the chlorhexidine group (15.2 deaths per 1000 livebirths) an
210 births, 18 450 (99.7%) newborn babies in the chlorhexidine group and 19 308 (99.8%) newborn babies in
212 17 468 (96.9%) of 18 015 neonates in the chlorhexidine group were available for complete follow-u
214 eriodontitis (e.g., scaling/root planing and chlorhexidine) have limited efficacy since they fail to
215 ClinicalTrials.gov website: povidone-iodine, chlorhexidine, hydrogen peroxide, cyclodextrin, Citrox,
217 were assigned to intranasal mupirocin and 2% chlorhexidine-impregnated cloths (active treatment, n =
218 eus, treatment with intranasal mupirocin and chlorhexidine-impregnated cloths compared with placebo s
219 olonization was also markedly reduced in the chlorhexidine-impregnated dressing group (random effects
223 catheter-related infections and the costs of chlorhexidine-impregnated sponge and contact dermatitis
225 atients, 28,931 catheter days) showed that a chlorhexidine-impregnated sponge decreased the incidence
226 ge use saved $197 per patient with the 3-day chlorhexidine-impregnated sponge dressing change strateg
229 incidence of 1.4 per thousand catheter days, chlorhexidine-impregnated sponge use saved $197 per pati
231 ce of multiresistant Gram-negative bacteria, chlorhexidine-impregnated sponges and Oligon catheters a
232 to evaluate the effect of daily bathing with chlorhexidine-impregnated washcloths on the acquisition
233 ed to bathe patients either with no-rinse 2% chlorhexidine-impregnated washcloths or with nonantimicr
236 e hypothesized that the ratio of fluoride to chlorhexidine incorporated into a resin, and the pH of t
237 ch lacks a homologue to SmvAR, resistance to chlorhexidine increased (4-fold) but plasmid carriage of
238 ps: 1) SRP + saline irrigation (C); 2) SRP + chlorhexidine irrigation (CHX); and 3) SRP + boric acid
239 ogic parameters and compare this method with chlorhexidine irrigation and SRP alone in patients with
240 new formulation consisting of erythritol and chlorhexidine is compared with the standard glycine powd
241 broad-spectrum, topical antimicrobial agent chlorhexidine is widely performed and may reduce health
245 suggest that daily bathing of patients with chlorhexidine may prevent hospital-acquired bloodstream
246 tion drainage endotracheal tubes, oral care, chlorhexidine mouth care, and daily spontaneous awakenin
248 ygiene measures and were advised to use 0.2% chlorhexidine mouthwash for 1 week before being allocate
249 nical therapy and its association with 0.12% chlorhexidine mouthwash reduced peri-implant mucositis.
252 36 911 newborn babies were enrolled into the chlorhexidine (n=18 015) and dry cord care study (n=18 8
253 density and the antimicrobial mechanisms for chlorhexidine, nano-silver, quaternary ammonium methacry
254 f a synergistic effect with the bisguanidine chlorhexidine on cell membrane disruption has been obser
255 s with disposable cloths impregnated with 2% chlorhexidine or nonantimicrobial cloths as a control.
256 rogram with refresher education campaign, 2) chlorhexidine oral hygiene program, 3) chlorhexidine bat
257 257) received scaling and root planing plus chlorhexidine oral rinse at baseline and supportive peri
258 cluding manual tooth/gum brushing plus 0.12% chlorhexidine oral rinse, twice per day, plus upright po
262 pedic, 61 vascular, and 56 other), mupirocin/chlorhexidine reduced 1-year mortality: 11 of 365 (3.0%)
263 harynx and the gastric tube plus a mupirocin/chlorhexidine regimen in intubated patients and standard
265 e of fluoride salt substantially reduced the chlorhexidine release, while the presence of a specific
266 d acidic residue, although unable to mediate chlorhexidine resistance and transport, was still able t
269 of the regulator SmvR, through adaptation to chlorhexidine, results in increased resistance to a numb
271 n rates after the stepwise implementation of chlorhexidine "scrub-the-hub" and daily baths in surgica
272 implemented at different times in the units: chlorhexidine "scrub-the-hub," chlorhexidine daily baths
274 while the presence of a specific quantity of chlorhexidine significantly increased fluoride release.
275 uorouracil (RR, 0.34 [95% CI, .14-.82]), and chlorhexidine-silver sulfadiazine (RR, 0.60 [95% CI, .50
276 which included a preoperative shower with 4% chlorhexidine soap, appropriate hair removal, adequate p
277 e effect of umbilical cord cleansing with 4% chlorhexidine solution on neonatal mortality and omphali
278 rol) or topical application of 10 mL of a 4% chlorhexidine solution once per day until 3 days after c
279 an those of free TVO, TVO nanoemulsions, and chlorhexidine solutions against E. coli and S. aureus.
280 he next most highly overexpressed gene under chlorhexidine stress was annotated as encoding a hypothe
282 human pathogen, Acinetobacter baumannii, to chlorhexidine to identify the primary chlorhexidine resi
286 reduced chlorhexidine susceptibility during chlorhexidine use in a patient with two episodes of cuta
287 ng semirecumbent positioning, oral care with chlorhexidine, venous thromboembolism prophylaxis, stres
288 lity: 11 of 365 (3.0%) died in the mupirocin/chlorhexidine versus 21 of 301 (7.0%) in the placebo gro
289 ring blood culture contamination rates using chlorhexidine versus iodine tincture for skin antisepsis
290 -related bloodstream infection (CR-BSI) with chlorhexidine versus nonchlorhexidine dressings and cath
292 xin/tobramycin/amphotericin B plus mupirocin/chlorhexidine was associated with the reduction of all-c
293 FU counts (P < 0.01 versus control), whereas Chlorhexidine was least effective; biofilm imaging resul
296 that preoperative MRSA decontamination with chlorhexidine washcloths and oral rinse and intranasal p
297 eo about MRSA decontamination and were given chlorhexidine washcloths and oral rinse and nasal povido
299 ions, mechanical and oral bowel preparation, chlorhexidine washes, and carbohydrate drink to all pati
301 est group (basic periodontal therapy + 0.12% chlorhexidine) with 61 implants; and control group (basi