ライフサイエンスコーパス: cholesterol esterase

1 r contact with bacterial enzymes (lipase and cholesterol esterase).

2 s by 2 esterases, pseudocholine esterase and cholesterol esterase.

3 g can produce highly selective inhibitors of cholesterol esterase.

4 resence of taurocholate, an activator of the cholesterol esterase.

5 hat were previously treated with the enzyme, cholesterol esterase (0.2 unit/mL).

6 cetylated LDL increased bile salt-stimulated cholesterol esterase activity in the conditioned media o

7 The structure of pancreatic cholesterol esterase, an enzyme that hydrolyzes a wide v

8 ng solutions and with the bacterial enzymes (cholesterol esterase and lipase).

9 phages synthesized only bile salt-stimulated cholesterol esterase and not the hormone-sensitive lipas

10 The combination of cholesterol esterase and sphingomyelinase led to a signi

11 esults point to a synergistic effect between cholesterol esterase and sphingomyelinase, suggesting th

12 ide lipases is truncated in the structure of cholesterol esterase and therefore is not a salient feat

13 Plasma was digested with lipase and cholesterol esterase, and carotenoids were extracted and

14 r on reconstituted HDL was inhibited by anti-cholesterol esterase antibodies.

15 ding the inhibition of pancreatic lipase and cholesterol esterase, as well as cholesterol micelle for

16 The involvement of pancreatic cholesterol esterase (bile salt-stimulated lipase) in ch

17 The synthesis of bile salt-stimulated cholesterol esterase by human macrophages was confirmed

18 The expression of bile salt-stimulated cholesterol esterase by human macrophages, in a process

19 Inhibition of pancreatic cholesterol esterase by this series of pyrones was marke

20 the inhibition of pancreatic lipase (PL) and cholesterol esterase (C-Ease) enzymes.

21 nd addition of gastric lipase (GL) (60U/mL), cholesterol esterase (CE) (0.075 or 2U/mL) or both.

22 minescence assay for total cholesterol using cholesterol esterase/cholesterol oxidase coupled with th

23 Treatment of LDL with cholesterol esterase converts LDL into cholesterol-rich

24 o and ex vivo samples were quantified with a cholesterol esterase enzymatic reaction.

25 Interactions of mammalian pancreatic cholesterol esterases from pig and rat with a family of

26 m cells to produce mice lacking a functional cholesterol esterase gene.

27 The physiologic role of the systemic cholesterol esterase has not been clearly defined.

28 sitive lipase (HSL), which acts as a neutral cholesterol esterase in macrophages and is a rate-limiti

29 nity of the carbamate for the active site of cholesterol esterase in the reversible, noncovalent comp

30 e demonstrate that both phospholipase A2 and cholesterol esterase increase cholesterol uptake by hydr

31 esults of the current study also showed that cholesterol esterase increased free-to-esterified choles

32 structure and composition contributes to the cholesterol esterase-induced cellular uptake of HDL-asso

33 PLE extracts showed higher antioxidant, cholesterol esterase inhibition, and ACE inhibitory acti

34 This class of cholesterol esterase inhibitors functioned as simple com

35 However, cholesterol esterase is more effective than pseudocholin

36 Bile salt stimulated cholesterol esterase is predominantly synthesized in the

37 These results indicate that cholesterol esterase is responsible for mediating intest

38 ted carboxyl ester lipase (CEL), also called cholesterol esterase, is one of the major proteins secre

39 Cholesterol esterase knockout mice and their wild type c

40 These results suggest that liver-derived cholesterol esterase may play an important role in cellu

41 observations, we propose that liver-derived cholesterol esterase may play an important role in lipop

42 Cholesterol esterase-mediated transformation of LDL into

43 lipase mRNA but not the bile salt-stimulated cholesterol esterase mRNA.

44 significantly different between control and cholesterol esterase-null mice fed either control or an

45 radiolabel was detected in the serum of the cholesterol esterase-null mice in comparison with that d

46 results were similar between the control and cholesterol esterase-null mice regardless of whether the

47 d was found to be similar in the control and cholesterol esterase-null mice.

48 was used as a model to determine the role of cholesterol esterase on hepatic uptake of high density l

49 Carboxyl ester lipase (CEL, also called cholesterol esterase or bile salt-dependent lipase) is a

50 In the absence of cholesterol esterase or phospholipase A2, uptake of chol

51 ntanoyloxy)-8,8'-biquinolyl (4) with a crude cholesterol esterase preparation (from bovine pancreas)

52 ution crystal structure of bovine pancreatic cholesterol esterase (Rcryst = 21.1%; Rfree = 25.0% to 1

53 ction is n = 6 and n = 7 for porcine and rat cholesterol esterases, respectively, equivalent to eight

54 d recognition by the extended active site of cholesterol esterase that are prominent determinants of

55 monstrating the ability of exogenously added cholesterol esterase to further enhance hepatic uptake o

56 safety, tolerability and efficacy of a novel cholesterol esterase transfer protein (CETP) inhibitor T

57 hat cholesterol-rich liposomes produced from cholesterol esterase-treated LDL can cause human monocyt

58 ines were induced in normal PTS by exogenous cholesterol esterase treatment, proportionate lethal cel

59 Cholesterol oxidase and cholesterol esterase were assembled on the surface of gr

60 Selectivities for cholesterol esterase were greater than 10(3).

61 However, bile salt-stimulated pancreatic cholesterol esterase, which has been proposed to mediate

62 These haloesters were simple substrates of cholesterol esterase with no evidence of irreversible in

63 loped by integrating cholesterol oxidase and cholesterol esterase with the hybrid material.

64 onucleotide primers for bile salt-stimulated cholesterol esterase yielded positive reactions with RNA