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1 he reaction of flavin oxidation catalyzed by choline oxidase.
2 which is <6 A from the flavin C(4a) atom in choline oxidase.
3 1.86 A resolution X-ray crystal structure of choline oxidase.
4 eptor in the tunneling reaction catalyzed by choline oxidase.
5 located on the solvent accessible surface of choline oxidase.
6 e reaction of choline oxidation catalyzed by choline oxidase.
7 e reaction of choline oxidation catalyzed by choline oxidase.
8 oning of the substrate in the active site of choline oxidase.
9 g characterization of the resulting forms of choline oxidase.
10 hydrogen peroxide in a reaction catalyzed by choline oxidase.
11 enings in serum is reduced by treatment with choline oxidase.
12 ctive amination steps based on an engineered choline oxidase (AcCO(6)) and a reductive aminase (NfRed
13 upled enzymatic reactions catalyzed by AChE, choline oxidase and horseradish peroxidase, leading to p
15 fects with 1,2-[2H4]choline as substrate for choline oxidase at 0.2 mM oxygen to gain insights on the
16 ues were observed as compared with wild-type choline oxidase at pH 10 and 25 degrees C, with no signi
17 ctive hypothesis of whether the mechanism of choline oxidase can be extended to other flavin-dependen
18 in codA transgenic plants, as a byproduct of choline oxidase-catalyzed GB synthesis, might activate t
26 coupling of acetylcholinesterase (AChE) and choline oxidase (ChO) by their reaction with glutaraldeh
27 ) (PoPD) and acetylcholinesterase (AChE) and choline oxidase (ChO) enzymes were fabricated on carbon
28 a mixture of acetylcholinesterase (AChE) and choline oxidase (ChO) onto nanocomposite of chitosan (CH
29 ing enzymes, acetylcholinesterase (AChE) and choline oxidase (ChO), on the surface of iron oxide nano
32 is based on measurement of H2O2 generated by choline oxidase (ChOx) in the presence of choline (Ch).
33 to form choline that is in turn oxidized by choline oxidase (ChOx) to produce betaine and H(2)O(2),
34 ACh to choline, which in turn is oxidized by choline oxidase (ChOx) to produce betaine and H2O2 that
38 nitoring their inhibitory effects toward the choline oxidase enzyme, through the amperometric measure
39 he wild-type and a number of mutant forms of choline oxidase from Arthrobacter globiformis have recen
40 ine-oxidizing enzyme is the flavin-dependent choline oxidase from Arthrobacter globiformis, for which
42 ults presented in this study suggest that in choline oxidase, His(466) modulates the electrophilicity
44 the protein charge near the FAD N(1) locus, choline oxidase lost the ability to stabilize negative c
45 d oxidation of glucose, acetylcholinesterase/choline oxidase-mediated hydrolysis and oxidation of ace
46 is data on His466, allow us to conclude that choline oxidase must necessarily utilize a strategy for
47 fer reaction in which choline is oxidized by choline oxidase occurs quantum mechanically within a pre
48 We propose that the side chain of Val464 in choline oxidase provides a nonpolar site that is require
49 ected two enzymes (glucose dehydrogenase and choline oxidase) that react with their respective model
50 cent study showed that in the active site of choline oxidase the protein positive charge is provided
51 nt determination of the crystal structure of choline oxidase to a resolution of 1.86 A established th
52 e of Arthrobacter globiformis, which encodes choline oxidase to catalyze the conversion of choline to
53 The hydride transfer reaction catalyzed by choline oxidase under irreversible regime, i.e., at satu
54 ate the mechanism for substrate oxidation by choline oxidase using both steady-state kinetics and rap
58 sm for the oxidation of choline catalyzed by choline oxidase was recently elucidated by using kinetic
59 served asparagine residue at position 510 in choline oxidase was replaced with alanine, aspartate, hi
60 nserved histidine residue at position 466 of choline oxidase was replaced with an alanine residue by
61 talytic parameters with respect to wild-type choline oxidase were seen in the Asn510Ala enzyme, with
62 other biomolecule, choline, by coupling with choline oxidase, which generates H2O2 during oxidation.
63 ransgenic plants express codA and synthesize choline oxidase, while accumulating GB in their leaves a