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1 disrupt the presynaptic polarity of this DA cholinergic neuron.
2 on the membrane potential of basal forebrain cholinergic neurons.
3 FFA3 is expressed in enteric cholinergic neurons.
4 tions for modulation of cortical function by cholinergic neurons.
5 release of GABA by knocking out Slc32a1 from cholinergic neurons.
6 nervous system displays little or no loss of cholinergic neurons.
7 has been used for many years for visualizing cholinergic neurons.
8 e excited by neighboring BF and/or brainstem cholinergic neurons.
9 in annelid worms by rhythmically activating cholinergic neurons.
10 networks of splicing events in GABAergic and cholinergic neurons.
11 eives cholinergic input from basal forebrain cholinergic neurons.
12 ral telencephalon give rise to GABAergic and cholinergic neurons.
13 from healthy and diseased human patients to cholinergic neurons.
14 c degeneration and a significant loss of PPN cholinergic neurons.
15 e development of telencephalic GABAergic and cholinergic neurons.
16 c neurons, along with the pronounced loss of cholinergic neurons.
17 holine (ACh) levels resulting from a loss of cholinergic neurons.
18 e physiological importance of this kinase in cholinergic neurons.
19 onnectivity of the remaining basal forebrain cholinergic neurons.
20 on of the RMP when expressed specifically in cholinergic neurons.
21 Cannabinoid receptors are located on cholinergic neurons.
22 ograms that differentiate these two types of cholinergic neurons.
23 excitatory responses to dopamine in striatal cholinergic neurons.
24 e it regulates the phenotypic maintenance of cholinergic neurons.
25 the inhibitory GABAergic and the excitatory cholinergic neurons.
26 ic area, but there was no innervation by the cholinergic neurons.
27 ess is sensed by the class IV multidendritic cholinergic neurons.
28 ithin the MLR: glutamatergic, GABAergic, and cholinergic neurons.
29 of local GABAergic and a minority of septal cholinergic neurons.
30 modulating the excitability of medial septal cholinergic neurones.
32 l arborizations of the mesopontine tegmental cholinergic neurons, a cell group in which CHT expressio
33 the Abeta42 amyloid plaque burden, reversing cholinergic neuron abnormalities, and generating a neuro
35 and cholinergic neurons where, importantly, cholinergic neuron activation is gated by SubC activity.
36 acetylcholine released from septohippocampal cholinergic neurons acts to modulate hippocampal microci
38 nctional maturation and maintenance of these cholinergic neurons after the differentiation stage have
41 se model of AD prevented the degeneration of cholinergic neurons, ameliorated corresponding deficits,
42 s disease (AD) prevented the degeneration of cholinergic neurons, ameliorated corresponding deficits,
45 y, graded signals that emanate from striatal cholinergic neurons and engage the canonical GDNF recept
46 le cells receive excitatory innervation from cholinergic neurons and inhibitory innervation from GABA
47 ion that destroyed 40-50% of basal forebrain cholinergic neurons and later, after extinction training
48 ever, GABA neurons lie intermingled with the cholinergic neurons and may contribute to or oppose this
51 ion of melanocortin-4 receptors inhibits DMV cholinergic neurons and optogenetic inhibition of liver-
52 ) on excitability of specific populations of cholinergic neurons and provide a framework for understa
53 ographic mapping between the basal forebrain cholinergic neurons and their axonal projections to the
54 ular nucleus basalis significantly protected cholinergic neurons and their cortical projections again
55 ed to label preganglionic and postganglionic cholinergic neurons and their projections to lymphoid ti
56 atural, movement-related signals of striatum cholinergic neurons and their relationship to simultaneo
57 paired integrity of pedunculopontine nucleus cholinergic neurons and their thalamic efferents play a
58 ory motoneurons and descending interneurons, cholinergic neurons, and intrinsic primary afferent neur
60 ng green fluorescent protein specifically in cholinergic neurons (APP.PS1/CHGFP) and in wild-type lit
67 ike previous studies of BF glutamatergic and cholinergic neurons, arousals induced by stimulation of
68 Guo et al. (2019) implicate basal forebrain cholinergic neurons as providing a link between auditory
69 ncies of the effector lines in aminergic and cholinergic neurons assessed here may help researchers t
70 employed optogenetics to control mesopontine cholinergic neurons at somata and at divergent projectio
73 the cholinergic phenotype in basal forebrain cholinergic neurons (BFCN) during development and protec
74 ) synthesis and release from basal forebrain cholinergic neurons (BFCN) innervating the cerebral cort
77 Age-related degeneration of basal forebrain cholinergic neurons (BFCNs) is linked to cognitive impai
79 rlying the selective loss of basal forebrain cholinergic neurons (BFCNs), a well-recognized character
80 in PC12 cells, cultured rat basal forebrain cholinergic neurons (BFCNs), and BFCNs from a mouse mode
83 hysiology, and behavior, we demonstrate that cholinergic neurons, but not peptidergic neurons, of the
84 that orexin-A and -B excite basal forebrain cholinergic neurons, but orexin-producing neurons also m
85 t depending on their state of activation, BF cholinergic neurons can be excited or inhibited by signa
92 s the PD patients had significantly more PPN cholinergic neurons containing mtDNA deletion levels exc
93 t increased dopamine sensitivity of striatal cholinergic neurons contributes to the expression of LID
94 of "selective" optogenetic stimulation of BF cholinergic neurons could be mediated by local excitatio
95 h optogenetic stimulation of basal forebrain cholinergic neurons decreases the dependency that is com
96 at Caenorhabditis elegans touch receptor and cholinergic neurons display age-dependent morphological
97 n contrast, we found that GRK2 deficiency in cholinergic neurons does not alter cocaine-induced psych
101 ports survival of only a small proportion of cholinergic neurons during development; however, this si
102 elatively selective trait of basal forebrain cholinergic neurons early in adult life, and increases i
103 roduction) was inhibited by ~50% in cultured cholinergic neurons exposed to low nanomolar concentrati
104 Anatomical analysis showed that forebrain cholinergic neurons express the GABA synthetic enzyme Ga
105 Our results showed that activation of BF cholinergic neurons expressing hM3Dq receptors significa
106 ht and dark phases, whereas inhibition of BF cholinergic neurons expressing hM4Di receptors significa
108 Furthermore, optogenetic stimulation of cholinergic neurons/fibers caused a mecamylamine- and at
111 culture of skeletal muscle cells (C2C12) and cholinergic neurons, gliomaxneuroblastoma hybrid cells (
112 embryonic day (E)11.5, and the proportion of cholinergic neurons gradually increased during pre- and
114 l morphologies of individual basal forebrain cholinergic neurons has, until now, been technically bey
115 in presynaptic vesicles of monoaminergic and cholinergic neurons, has a regulatory role in dopamine h
116 we propose that the PPN and, in particular, cholinergic neurons have a central role in updating the
118 are not well understood, the basal forebrain cholinergic neurons have been implicated in stress respo
121 tion is poorly understood because identified cholinergic neurons have never been recorded during beha
122 ppression, the cochlear projections of these cholinergic neurons have not been described in humans.
123 charge profile and thus precise roles of the cholinergic neurons have remained uncertain because they
125 ce, with TASK channel deletion restricted to cholinergic neurons, immobilizing actions of the inhaled
133 from modulation by optogenetic activation of cholinergic neurons in basal forebrain, which led to a m
138 nderscore the causal role of basal forebrain cholinergic neurons in fast, bidirectional modulation of
139 optical stimulation of basal forebrain (BF) cholinergic neurons in mice increases local acetylcholin
140 ability of the magnocellular basal forebrain cholinergic neurons in neurodegenerative diseases, such
141 2-amino acid isoform, within basal forebrain cholinergic neurons in normal young, normal aged and Alz
142 and arousal, and in view of the loss of its cholinergic neurons in PD, the PPN could be involved in
143 regulates cholinergic function in rat septal cholinergic neurons in primary cultures from E18.5 embry
144 traditional methods, the precise role of BF cholinergic neurons in regulating the sleep-wake cycle r
145 oteins appear to be coexpressed with ChAT by cholinergic neurons in several motor and reticular nucle
146 njection of mu-p75-sap produced depletion of cholinergic neurons in the basal forebrain and decreased
149 , GPR30 in expressed by the vast majority of cholinergic neurons in the basal forebrain, and appears
150 branes of the somata, dendrites and axons of cholinergic neurons in the basal forebrain, striatum and
151 Previously it has been found that principal cholinergic neurons in the brain express high concentrat
152 istribution of glutamatergic, GABAergic, and cholinergic neurons in the brain of the African cichlid
156 level, we found reduced firing of identified cholinergic neurons in the brainstem pedunculopontine te
157 We also review and discuss the presence of cholinergic neurons in the BST, and of neuron population
159 HT) is a protein integral to the function of cholinergic neurons in the central nervous system (CNS).
160 , optogenetics and functional mapping reveal cholinergic neurons in the DMN, which project to the cel
161 minergic neurons in the substantia nigra and cholinergic neurons in the dorsal motor nucleus (DMnX),
162 rated in the late L1 and are postsynaptic to cholinergic neurons in the dorsal nerve cord but do not
164 s also expressed in both cholinergic and non-cholinergic neurons in the ENS of mouse, rat and human.
165 xpression of alpha-synuclein in the axons of cholinergic neurons in the guinea pig and human distal g
167 ;R26R-YFP mice to examine the development of cholinergic neurons in the gut of embryonic and postnata
168 of neurons surround Bar: rostral-dorsomedial cholinergic neurons in the laterodorsal tegmental nucleu
169 he phenotypic maintenance of basal forebrain cholinergic neurons in the mature and fully differentiat
171 ined from male and female mice indicate that cholinergic neurons in the medial septum represent a key
177 duced by selective optogenetic activation of cholinergic neurons in the nucleus accumbens (NAc) are i
178 of acetylcholine (ACh) into the cortex from cholinergic neurons in the nucleus basalis of Meynert (N
179 ore, this study aimed to clarify the role of cholinergic neurons in the pedunculopontine tegmentum (P
180 nculopontine tegmental nuclei (LDT and PPT), cholinergic neurons in the pontomesencephalic tegmentum
182 eus, no serotoninergic raphe neurons nor any cholinergic neurons in the PPT and LDT that projected to
185 nd demonstrate a role for MC4Rs expressed in cholinergic neurons in the regulation of insulin levels
186 e(+) transgenic rats, we selectively labeled cholinergic neurons in the rostral PPN, caudal PPN, and
187 NGF)-dependent neurons including sympathetic cholinergic neurons in the skin, causing anhidrosis.
190 rm depression (LTD)-related disinhibition of cholinergic neurons in the vestibular nuclei--suppresses
192 eceptor kinase A (TrkA) expression in septal cholinergic neurons in vitro and in vivo, resulting in r
193 more, re-expression of MC4Rs specifically in cholinergic neurons (including sympathetic preganglionic
194 and activation of cortically projecting, non-cholinergic neurons, including the GABAergic/PV neurons.
195 ave shown that "selective" stimulation of BF cholinergic neurons increases transitions between NREM s
197 ely results in activation of basal forebrain cholinergic neurons increasing release of ACh onto presy
198 GABAergic and glycinergic neurons; however, cholinergic neurons indicated down-regulation of the sam
199 hat has both parvocellular and magnocellular cholinergic neurons, indicates an unusual sleep phenomen
200 se (AD), usually ascribed to degeneration of cholinergic neurons induced by the amyloid-beta peptide
201 on of this inhibitory olfactory microcircuit.Cholinergic neurons innervate multiple layers in the mai
202 ic deficits occur in Parkinson's disease and cholinergic neurons innervate regions, such as the limbi
204 ts on the specification of glutamatergic and cholinergic neurons into a nervous system-wide regulator
207 -related neuroplasticity of septohippocampal cholinergic neurons is capable of increasing neuronal ex
209 ddition, a potential absence of hypothalamic cholinergic neurons is suggestive of unusual patterns of
210 dings reveal that the primary function of BF cholinergic neurons is to inhibit EEG delta activity thr
212 we demonstrated that optical stimulation of cholinergic neurons locally increased acetylcholine leve
213 activity, as "W/PS-max active neurons." Like cholinergic neurons, many GABAergic and glutamatergic ne
214 that contains the highest density of lightly cholinergic neurons, many of which are glutamatergic, wh
215 , excitatory input from the Pf onto striatal cholinergic neurons may facilitate behavioral flexibilit
216 attern was observed in which the position of cholinergic neurons measured along a rostral to caudal e
217 , we selectively removed MeCP2 function from cholinergic neurons (MeCP2 ChAT KO), which recapitulated
218 hodopsin or halorhodopsin in basal forebrain cholinergic neurons of mice with optic fibers directed i
219 ial activity of cholinergic interneurons and cholinergic neurons of the brainstem during reward-relat
221 gic neurons of the substantia nigra (SN) and cholinergic neurons of the dorsal motor nucleus of the v
222 d reduced NMDA receptor-mediated currents in cholinergic neurons of the medial septum in mGluR5 KO mi
229 effects of cell-selective manipulation of BF cholinergic neurons on the sleep-wake behavior and elect
230 Selective optogenetic activation of DMN cholinergic neurons or electrical activation of the cerv
232 of hearing, descending (efferent) input from cholinergic neurons originating in the brainstem inhibit
234 e pontomesencephalic tegmentum, particularly cholinergic neurons, play an important role in cortical
235 n heavily populated by cortically projecting cholinergic neurons, precedes and predicts entorhinal de
236 n output neurons, chemogenetic inhibition of cholinergic neurons produced similar perturbations in ol
240 brain and its specific removal in excitatory cholinergic neurons recapitulates the female courtship b
242 demonstrate that the elimination of GRK2 in cholinergic neurons reduces sensitivity to select muscar
250 ome lines, restoration of FruM expression in cholinergic neurons restores fertility or reduces male-m
253 on of neural progenitor cells and new mature cholinergic neurons, revealing an important mitogenic ro
255 aturation into GABAergic, glutamatergic, and cholinergic neurons, showing entangled electrically acti
256 Finally, we found that activation of BF cholinergic neurons significantly increased c-Fos expres
257 itulated in mice with pan-neuron-specific or cholinergic neuron-specific ablation of the cpeb2 gene.
258 neurons and decreased Ras/MAPK signaling in cholinergic neurons specifically inhibit the adaptive ha
259 ent in vitro study from our group found that cholinergic neurons strongly excite neighboring GABAergi
261 AbetaOs selectively bind to ~50% of cultured cholinergic neurons, suggesting that ChAT is fully inhib
262 with losses of basal forebrain and striatal cholinergic neurons, suggesting that falls reflect disru
263 rs to the mPFC follow four pathways and that cholinergic neurons take these routes depending on their
264 ouse gastrointestinal tract co-localize with cholinergic neurons that express the neuropeptide neurom
265 is therefore a feature specific to principal cholinergic neurons that innervate the central nervous s
266 insulin release by activating non-ganglionic cholinergic neurons that innervate the islets, presumabl
267 autonomous program of synapse elimination in cholinergic neurons that likely occurs when protein prod
268 contains a variety of cell types, including cholinergic neurons that project to the rostral aspect o
269 nucleus of the vagus (DMV), a population of cholinergic neurons that show signs of pathology in the
271 /SI region, and dynorphin-A inhibits MCPO/SI cholinergic neurons through kappa-opioid receptors by (1
272 study describes the spatial distribution of cholinergic neurons throughout the brain of the weakly e
273 precise contributions of the medial septum's cholinergic neurones to these functions remain unknown.
274 eveloped hiPSC-derived Aged dopaminergic and cholinergic neurons to model PD and related synucleinopa
276 ne in mice (CHT(+/-)) limits the capacity of cholinergic neurons to sustain acetylcholine (ACh) relea
277 complicated by the widespread projections of cholinergic neurons to telencephalic structures that the
279 ferential recruitment of two basal forebrain cholinergic neuron types generates behavior-specific cor
281 mato in medial septum/diagonal band of Broca cholinergic neurons using Cre recombinase-dependent aden
282 on their activity might support, we recorded cholinergic neurons using optogenetic identification in
283 rmined the effects of dynorphin-A on MCPO/SI cholinergic neurons using patch-clamp recordings in brai
285 ynorphin-A directly inhibits basal forebrain cholinergic neurons via kappa-opioid receptors, and decr
287 ensity of axodendritic thalamic terminals on cholinergic neurons was due to their dendritic territory
288 eep deprivation resulting from activation of cholinergic neurons was sufficient to elicit subsequent
294 olinergic basal forebrain population-but not cholinergic neurons-were correlated with trial-to-trial
295 excitatory interaction between the SubC and cholinergic neurons where, importantly, cholinergic neur
298 to convert human fetal lung fibroblasts into cholinergic neurons with high purity (>90%) and efficien
299 hannelrhodopsin is endogenously expressed in cholinergic neurons with Htr3a-Cre mice, in which Cre is
300 rect effects of estradiol on basal forebrain cholinergic neurons, with corresponding effects on cogni