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1 ughout the nucleus but was excluded from the chromocenter.
2 tuin 1 (Sirt1) protein from contact with the chromocenter.
3 ns of all polytene chromosomes into a single chromocenter.
4 the full complement of chromosomes into the chromocenter.
5 r ectopic binding to autosomal sites and the chromocenter.
6 e universal importance of satellite DNAs and chromocenters.
7 binds heterochromatic satellite repeats and chromocenters.
8 eterochromatin compaction within conspicuous chromocenters.
9 ids and Brdt and Sirt1 overlapped around the chromocenters.
10 centromeric heterochromatin) into peripheral chromocenters.
11 teracting domain [CRID]) to redirect LANA to chromocenters.
12 ated genomic loci in vivo and is enriched in chromocenters.
13 tiple chromosomes into nuclear foci known as chromocenters.
14 rochromatinized and cluster together to form chromocenters.
15 he aberrant spermatid nuclei is a fragmented chromocenter, a structure comprised of peri-centromeric
16 within G1-phase nuclei, we demonstrate that chromocenters acquire the property of late replication c
17 he formation and/or maintenance of an intact chromocenter and implicate this structure in proper remo
18 inct subnuclear locations distinguishable by chromocenter and nucleolus landmarks, suggesting that PH
19 ene chromosomes revealed localization at the chromocenter and to the 49 CD region on the right arm of
20 e and potency which determine their ratio at chromocenters and are critical for genome stability and
21 s of POU5F1 (also known as OCT4) protein and chromocenters, and the conversion of the chromatin lands
24 o characterize the molecular features of the chromocenter as well as the chromosome territory contain
26 orescence microscopy revealed densely packed chromocenters associated with H3K9me3-a conserved marker
27 s, D1 and Prod, as baits to characterize the chromocenter-associated proteome in Drosophila embryos,
28 t of late replication, and removing HP1 from chromocenters by competition with Me3K9H3 peptides did n
30 D2 inhibits heterochromatin association into chromocenters, coincident with losses in cytosine methyl
31 Furthermore, KRP5 overexpression increases chromocenter decondensation and endoreduplication in the
32 ransposons and to decondense heterochromatic chromocenters, despite only minor changes in the mainten
34 hibiting enhanced phenotypes associated with chromocenter disruption, revealing the universal importa
35 HP1 binding at chromocenters, replication of chromocenter DNA was advanced by 10-15% of the length of
37 ellite DNAs into nuclear structures known as chromocenters ensures encapsulation of all chromosomes i
38 tigated the molecular mechanisms involved in chromocenter formation during the switch from a heterotr
39 result in defective spermatid elongation and chromocenter formation in the developing germ cells.
40 linker histone H1 before repeat clustering, chromocenter formation involves increasing enrichment in
42 ation of transcripts involved in DNA repair, chromocenter formation, and tumorigenesis in addition to
51 ication, HP1 binding, and aggregation at the chromocenter, in successive steps coordinated with devel
52 petitive heterochromatic loci into so-called chromocenters is an important determinant of chromosome
53 In this domain, we find that the number of chromocenters is reduced, as shown by chromatin staining
54 or locus of lambda 20p1.4 hybridization, the chromocenter, is found juxtaposed to the nuclear envelop
55 gether, we propose that associations between chromocenter modules, consisting of satellite DNA bindin
56 acultatively condenses in cycling cells into chromocenters negative both for histone H3 dimethylated
57 e and morphology but a synergistic effect on chromocenter number (reduction) and whole-plant morpholo
58 s also displace HP1 from the heterochromatic chromocenter of polytene chromosomes in larval salivary
59 of euchromatic bands and the heterochromatic chromocenter of polytene chromosomes, and the H2Av antib
60 During spermiogenesis, SUMO-1 localized in chromocenters of certain round spermatids and perinuclea
61 ssion and reduced amount of cenH3 protein at chromocenters of meristematic nuclei, anaphase bridges d
62 like and/or dMBD-likeDelta is present at the chromocenter on larval polytene chromosomes as well as a
63 equired for LANA to colocalize with MeCP2 at chromocenters, regions of extensive pericentric heteroch
64 lication results in DNA damage and extensive chromocenter remodeling into unique structures we have n
65 t to, or "paints," major satellite blocks as chromocenters replicate, where topoisomerase is also enr
66 e for K9H3 trimethylation and HP1 binding at chromocenters, replication of chromocenter DNA was advan
67 that clustering of repetitive DNA loci into chromocenters takes place in a precise temporal window a
68 e chromosomes, HP2 and HP1 colocalize at the chromocenter, telomeres, and the small fourth chromosome
69 eins previously unlinked to satellite DNA or chromocenters, thereby laying the foundation for a compr
70 a), suggesting that the presence of multiple chromocenters was correlated with a spread of heterochro
72 s studies in genetic models where fragmented chromocenters were observed in spermatids, the Brdt(BD1/
73 , we reveal a 5-formylcytosine (5fC) nuclear chromocenter, which transiently forms during zygotic gen
74 ind a strong and distinct H3.1 enrichment at chromocenters, with variation in mouse embryonic stem ce