ライフサイエンスコーパス: chromosome 15

1 apped the vic2 locus to the telomeric end of chromosome 15.

2 reen fluorescent protein (eGFP) transgene on chromosome 15.

3 e of a potential tumor suppressor gene(s) on chromosome 15.

4 ve overlapping deletions of the right arm of chromosome 15.

5 the mESO3, psimESO3, was identified on mouse chromosome 15.

6 he Crc gene to a region of 8.8 cM on central chromosome 15.

7 BALB/cJ trait had been mapped to a locus on chromosome 15.

8 s genetic mapping placed Bcmd near Srebf2 on chromosome 15.

9 lite markers spanning the entire long arm of chromosome 15.

10 orresponding to the syntenic region of human chromosome 15.

11 synteny between mouse chromosome 9 and human chromosome 15.

12 gh-resolution map of the Afr1 locus on mouse chromosome 15.

13 by D15S983 and distally by D15S127 on human chromosome 15.

14 linked to the Trhr and D15Bir7 loci on mouse chromosome 15.

15 approximately 20-centimorgan (cM) region of chromosome 15.

16 ntaining HuAZ2 at band 22 of the long arm of chromosome 15.

17 in the syntenic 15q15-q21.1 region of human chromosome 15.

18 ique clones representing specific regions of chromosome 15.

19 , has been cloned, sequenced and assigned to chromosome 15.

20 and the corresponding germ-line region from chromosome 15.

21 lusively or preferentially from the maternal chromosome 15.

22 fluorescence in situ hybridization (FISH) to chromosome 15.

23 promyelocytic leukemia (PML) gene located on chromosome 15.

24 (SSLPs); one additional tumor showed LOH on chromosome 15.

25 argazer region has been constructed on mouse Chromosome 15.

26 chromosome 2 in a region syntenic with human chromosome 15.

27 ybridization data that map the mouse gene to chromosome 15.

28 rrangements of the pericentromeric region of chromosome 15.

29 chromosomes, although three of twelve are on chromosome 15.

30 nce of human galactokinase reported to be on chromosome 15.

31 15q11-q13 or paternal uniparental disomy of chromosome 15.

32 required to determine the parental origin of chromosome 15.

33 The mouse gene localized to distal chromosome 15.

34 encoded in a cluster of paralogous genes on chromosome 15.

35 f an imprinted locus on paternally inherited chromosome 15.

36 and rs4779584, rs11632715, and rs73376930 on chromosome 15.

37 lutionary and disease-related instability of chromosome 15.

38 mon chromosome involved in the ASD group was chromosome 15.

39 eracting protein 1 gene (PSTPIP1) located on chromosome 15.

40 yeloid leukemogenesis and suppressed gain of chromosome 15.

41 ds of cases as a result of trisomy for mouse chromosome 15.

42 al mutant ataxia3 was mapped to distal mouse chromosome 15.

43 slocations that involve NUT, a novel gene on chromosome 15.

44 le signals in the OCA2/HERC2/APBA2 region on chromosome 15.

45 CYP1A2 are in a head-to-head orientation on chromosome 15.

46 located in the Prader-Willi region of human chromosome 15.

47 to galactokinase, was subsequently mapped to chromosome 15.

48 21Rk useful as a balancer for proximal mouse chromosome 15.

49 a sixth family member, CELF6, was located on chromosome 15.

50 nd we mapped the mutation in one pedigree to chromosome 15.

51 ch inv dup(15), compared with that on normal chromosomes 15.

52 duplication arose de novo from her father's chromosomes 15.

53 rential association of maternal and paternal chromosomes 15.

54 ), chromosome 11 (8 additional markers), and chromosome 15 (15 additional markers).

55 ved alleles of maternally imprinted genes on chromosome 15 (15q11-13).

56 Linkage maps of rat chromosomes 15, 16, 17, 19, and X were constructed by mu

57 These linkage groups were assigned to rat chromosomes 15, 16, 17, 19, and X, respectively, either

58 for maternal meiosis I (MI) errors involving chromosomes 15, 16, 18 and 21 and increased recombinatio

59 LOH for markers on chromosomes 15, 18, 21, and X was infrequent in leiomyos

60 alterations in the positioning of the human chromosomes 15, 18, X and Y between spermatozoa with the

61 chromosome 7 (80%), chromosome 12 (47%), and chromosome 15 (73%) and partial loss of chromosome 4 (87

62 1 (121 Mb, LOD=5.6) and a suggestive QTL on chromosome 15 (76 Mb, LOD=3.5).

63 of the first carpometacarpal (CMC) joint on chromosome 15 (81 cM; LOD score 6.25).

64 nd 163 Mb, LOD=6.8), and a suggestive QTL on chromosome 15 (96 Mb, LOD=4.7).

65 We identified two DMRs on chromosome 15, a chromosome that was not thought to cont

66 he disease gene within a 17.4 Mb interval on chromosome 15, a region containing 296 genes.

67 uit weight locus fw1 from 3.41 to 3.76 Mb on chromosome 15, a region under selection during domestica

68 fic deficiencies in the percentage of paired chromosome 15 alleles were observed in RTT, AS and autis

69 Replication timing was evaluated for chromosome 15 and 17 loci.

70 gical behavior of this cancer, we mapped the chromosome 15 and 19 translocation breakpoints by fluore

71 used by paternal uniparental disomy (UPD) of chromosome 15 and 2-3% are caused by "imprinting mutatio

72 13 loci in hybrids containing a single human chromosome 15 and at two chromosome 11p15 loci in hybrid

73 rfv3) gene, the rfv3 gene has been mapped to chromosome 15 and confers resistance to MuLV but not to

74 arate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.

75 e Prader-Willi syndrome IC (PWS-IC) on human chromosome 15 and mouse chromosome 7 regulates imprinted

76 and indirect effects of copy number gains in chromosome 15 and provides a framework for the study of

77 RHCG and Rhcg map at 15q25 of human chromosome 15 and the long arm of mouse chromosome 7, re

78 rom the targeted ES cells carry the inverted chromosome 15 and, at the same time, exhibit lighter coa

79 ons such as loss of chromosome 6 and gain of chromosomes 15 and 12p in the former.

80 HM, two significant regions affecting HDL on chromosomes 15 and 16 and one affecting LDL on chromosom

81 bserved at regions orthologous to both human chromosomes 15 and 16 in non-human primates, including O

82 hromosome 1 and other NZO-contributed QTL on chromosomes 15 and 17, as well as with an NON-contribute

83 gene; in 3 cases with morphologically normal chromosomes 15 and 17, RARalpha was inserted into PML on

84 th a reciprocal chromosomal translocation of chromosomes 15 and 17, which results in a fusion protein

85 l/normal state of the sex chromosomes and of chromosomes 15 and 17.

86 Copy number changes affecting chromosomes 15 and 19 occurred first.

87 itutional Robertsonian translocation between chromosomes 15 and 21, rob(15;21)(q10;q10)c, have approx

88 on and involving loci corresponding to human chromosomes 15 and 21.

89 nt microscopy, the nuclear colocalization of chromosomes 15 and sSMC was analyzed.

90 EJ) contain complicons that coamplify c-myc (chromosome 15) and IgH (chromosome 12) sequences.

91 e 4-like; chromosome 18), Ano6 (anocatmin 6; chromosome 15), and Rnf220 (Ring finger protein 220; chr

92 Zhx2 is located on chromosome 15, and a natural hypomorphic mutation in the

93 lly derived copy of the proximal long arm of chromosome 15, and eat uncontrollably; in Angelman syndr

94 The lbc proto-oncogene maps to chromosome 15, and onco-lbc represents a fusion of the l

95 One found evidence of linkage to markers on chromosome 15, another to markers on chromosome 6, centr

96 This region located on chromosome 15 appears to the major one affecting habitua

97 MPFYVE is also located on chromosome 15, approximately 170 kb telomeric to AF15q14

98 Segmental duplications in chromosome 15 are largely clustered in two regions, on p

99 gamma-glutamylcyclotransferase 1 (CHAC1) on chromosome 15 as affected by GWAS variants by analyzing

100 enotype and maps to the same region of mouse chromosome 15 as the Caracul (Ca) and Reduced coat (Rco)

101 previously characterized and shown to retain chromosome 15 as the only human material.

102 otinic acetylcholine receptor) on a locus of chromosome 15 associated with mental illness, including

103 ssion of ATP10C thus make it a candidate for chromosome 15-associated autism and suggest that it may

104 50), chromosome 13 at 108 cm (LOD=2.10), and chromosome 15 at 108 cM (LOD=2.48).

105 but they differ in how neighboring genes on chromosome 15 at 15q11-q13 are affected.

106 disruptions of the gene UBE3A or deletion of chromosome 15 at 15q11-q13, which encompasses UBE3A and

107 -glyoxylate aminotransferase 2 locus, and on chromosome 15 at the glycine amidinotransferase locus, a

108 mapped to a 6.5-Mb region of the long arm of chromosome 15, at 22.33-24.2 between CYP11A and D15S211.

109 loom syndrome (BLM) has been mapped to human chromosome 15 band q26.1 by homozygosity mapping.

110 ound to reside at chromosome 5, band p21 and chromosome 15, band q26, respectively.

111 he cluster of type II keratin genes on mouse chromosome 15, between the keratin 6 (mK6alpha/mK6beta)

112 Deletions encompassing a four-gene region on chromosome 15 (BP1-BP2 at 15q11.2), seen at a population

113 In addition, we localized the chromosome 15 breakpoint to a 9-kb region in each of two

114 The causative gene maps to the long arm of chromosome 15 but has not yet been identified.

115 sition, that not only distinguish homologous chromosomes 15 but can be used to follow the transmissio

116 flowering plants, sex determination involves chromosome 15, but an XY system has changed to a ZW syst

117 of bands q11.2-q13 of the paternally derived chromosome 15, but it also occurs either because of mate

118 n has been mapped to the distal end of mouse chromosome 15, but the mutated gene has not been found.

119 Murine chromosome 15 carries the sex-affected Pgia8 locus that

120 tumors we observed whole or partial gain of chromosome 15 centering on 15D2-D3 (orthologous to human

121 mosome 15 from a lymphoblastoid cell line, a chromosome 15 centromere-specific DNA probe with a fluor

122 ral SLR within a repeat-rich region near the chromosome 15 centromere.

123 antitative trait locus (QTL) was detected on chromosome 15 (Chr 15) with a highly significant logarit

124 we identified two loci, Pgia8 and Pgia9, on chromosome 15 (chr15) that appear to be implicated in di

125 The VPS13C-C2CD4A-C2CD4B locus on chromosome 15 confers diabetes susceptibility in every e

126 ciation study (GWAS) approach, the region on chromosome 15 containing Basp1 was identified as being s

127 e Ashkenazi population to a 0.6-Mb region on chromosome 15 containing SCG5 (also known as SGNE1), GRE

128 Amplification of chromosome 15 containing the Myc gene was detected in al

129 mphomas with stereotypic karyotypes in which chromosome 15, containing the Myc oncogene, is gained wi

130 of eGFP expression, transgene abundance, and chromosome 15 copy number demonstrated that a prepondera

131 EF1B1, is actually a processed pseudogene on chromosome 15 corresponding to an alternative splice for

132 The data offer the first report of a chromosome 15 cosmid library and demonstrate the value o

133 s indicated that MRG15 (MORF-related gene on chromosome 15) could derepress the B-myb promoter by ass

134 ng inverted D segments, DIR family segments, chromosome 15 D segments and multiple D segments were fo

135 f a supernumerary pseudodicentric derivative chromosome 15 [der(15)] that has been called inverted du

136 Supernumerary marker chromosomes (SMCs) of chromosome 15, designated "SMC(15)s," are the most commo

137 as identified for POAG to an 11-cM region on chromosome 15, designated GLC1I.

138 A probe derived from the BCL8 locus on chromosome 15 detected a transcript in human testis and

139 s expressed only from the paternally derived chromosome 15, due to epigenetic imprinting.

140 drome (AS), Prader-Willi syndrome (PWS), and chromosome 15 duplication syndrome (Dup15q) may lead to

141 hildren were identified who had interstitial chromosome 15 duplications and were excluded from furthe

142 Recently, a chromosome 15 duplicon was discovered in the common brea

143 POLG, located on nuclear chromosome 15, encodes the DNA polymerase gamma(Pol gamm

144 are associated with variants in a region of chromosome 15 encompassing genes encoding the nicotinic

145 tion stage on chromosome 14, and 1 island on chromosome 15 for secondary cell wall deposition, for a

146 In an attempt to isolate human chromosome 15 from a lymphoblastoid cell line, a chromos

147 t increase in homologous pairing specific to chromosome 15 from infant to juvenile brain samples.

148 stic effect of both MYC and RAD21 in driving chromosome 15 gains.

149 is identical to a genomic DNA sequence from chromosome 15 (GenBank accession no. AC067805, bp 148976

150 l cloning approach for identifying the BBS4 (chromosome 15) gene, we identified and cloned an unconve

151 osome 12 to sequences downstream of c-myc on chromosome 15, generating dicentric chromosomes and c-my

152 J]F2 mice identified a major locus on distal chromosome 15, given the appellation Carg5, that regulat

153 diabetes susceptibility associated with the chromosome 15 GWAS locus.

154 (5.8%) had hypodiploid karyotypes: 87 had 45 chromosomes, 15 had 33 to 44 chromosomes, none had 29 to

155 y the deletion of small portions of maternal chromosome 15 harboring the UBE3A gene.

156 enotype is linked to a 20 Mb region of 129P2 chromosome 15 harboring the Wnt7b gene, which is prefere

157 icular hot spot for such oxidative attack on chromosome 15 has been found to align with several mutat

158 few cases of paternal uniparental disomy of chromosome 15 have been reported.

159 have identified a conserved region of human chromosome 15 homologous to the mesd, nelg, and hsdr1 fu

160 AC contigs, and FISH of normal or rearranged chromosomes 15 identified duplicated sequences (the END

161 Isodicentric chromosome 15 (Idic15), characterized by duplications of

162 for PWS, and 44.0% for combined detection of chromosome 15 imprinting disorders for the validation da

163 uggest that it is feasible to screen for all chromosome 15 imprinting disorders using SNRPN methylati

164 tion rate had also lost at least one copy of chromosome 15 in 70% of the cells.

165 The mouse ACAT-2 gene (Acact2) maps to chromosome 15 in a region containing a quantitative trai

166 ence-tagged site mapping places cPLA2beta on chromosome 15 in a region near a phosphoinositol bisphos

167 d is part of a complex of imprinted genes on chromosome 15 in mice and chromosome 8 in humans.

168 chromosome and an autosome corresponding to chromosome 15 in the Bombyx mori reference genome.

169 ti minigene was introduced onto the inverted chromosome 15 in the ES cells by gene targeting.

170 molecules have recently been mapped to human chromosome 15 in the region q22.3-q23 and to the synteni

171 ficant linkage to markers on the long arm of chromosome 15, in a region encompassing RLBP1, the gene

172 The eGFR-associated locus on chromosome 15 included intronic variants of RYR3 and was

173 TBLV insertions on chromosome 15 (including a newly identified locus, Pad7)

174 lly expressed genes at an imprinted locus on chromosome 15, including the long noncoding RNA IPW.

175 n cell line bearing a partial duplication of chromosome 15 increased the abundance of POLgammaCAT mRN

176 ed a major quantitative trait locus (QTL) on chromosome 15 influencing size variation within a single

177 ting in copy number loss of chromosome 6 and chromosome 15 instability, including amplification of a

178 the breakpoints of inverted duplications of chromosome 15 (inv dup[15]) that include the Prader-Will

179 The genomic locus on chromosome 15 is clonally rearranged in about 4% of DLCL

180 The assignment of the mouse Ku70 gene to chromosome 15 is consistent with the syntenic relationsh

181 As chromosome 15 is one of seven human chromosomes with a h

182 Interestingly, while chromosome 15 is still gained in MYC(Chr6) tumors after

183 t the sequence reported for galactokinase on chromosome 15 is that of GalNAc kinase, which can phosph

184 s of rDNAs and LORE-TEARS at the left end of chromosome 15 (LE-Chr15).

185 es have identified a bidirectional signal on chromosome 15, likely underlain by FANCD2- and FANCI-ass

186 unesterified cholesterol levels, whereas the chromosome 15 locus appears to influence both HDL-C conc

187 eterozygotes and C57BL/6J homozygotes at the chromosome 15 locus marker had higher bone mineral densi

188 rker, cotinine + 3'hydroxycotinine, shared a chromosome 15 locus near CHRNA5 with CPD and Pack-Years

189 further refined our signal for insulin 30 on chromosome 15 (LOD 2.38 at 68 cM).

190 rrower diagnosis of persistent stuttering on chromosome 15 (LOD = 1.95 at 23 cM).

191 angrenosum-acne-arthritis to the long arm of chromosome 15 (maximum two-point LOD score, 5.83; recomb

192 The data also indicate that the VH region on chromosome 15 may contain a large duplicated block with

193 form of a supernumerary inverted duplicated chromosome 15, more properly described as an isodicentri

194 The gene on chromosome 15 (MRG15) has high similarity to Drosophila

195 The MORF4-Related Gene on chromosome 15 (MRG15) is a member of a novel family of g

196 No GWS associations were observed at the chromosome 15 nicotinic receptor gene cluster (CHRNA5-CH

197 gene cluster on chromosome 12 of humans and chromosome 15 of mice.

198 Transgenes were integrated on proximal chromosome 15 of the A line and on the Y chromosome of t

199 sed by alterations of the paternally derived chromosome 15 or by maternal uniparental disomy.

200 , more properly described as an isodicentric chromosome 15, or idic(15).

201 In the mouse, Trib is located on chromosome 15, overlapping with and transcribed in the o

202 ation at the novel IL16/STARD5/TMC3 locus on chromosome 15 (P = 5.71 x 10(-7)).

203 ome patients who lack 15q11-q13 deletions or chromosome 15 paternal uniparental disomy.

204 I nondisjunction error involving an altered chromosome 15 produced by both a translocation event bet

205 eport that a new quantitative trait locus on chromosome 15, Rapop5, partly accounts for the murine st

206 ity among SMC(15)s that is not seen in other chromosome 15 rearrangements, such as deletions and dupl

207 tive for SNRPN expression were found to have chromosome 15 rearrangements, while the diagnosis of PWS

208 scent in situ hybridization we mapped Zfr to chromosome 15 region A.

209 non-major histocompatibility complex gene on chromosome 15 regulates long-term survival and is locate

210 icons-a approximately 14-kb primate-specific chromosome 15 repeat that became organized into larger p

211 cripts from the 200-kb human GRINL1A gene on chromosome 15 revealed a complex gene structure comprisi

212 tified, located between UNC13C and RAB27A on chromosome 15 (rs7181788, p = 1.01 x 10(-08)) and in USP

213 ent 15q13.3 microdeletions, the expansion of chromosome 15 segmental duplications in the human lineag

214 the CYP1A locus, we scanned 75 kilobases of chromosome 15 sequence for high-affinity AhR binding sit

215 ach patient had maternal heterodisomy of the chromosome 15 short arm, whereas PCR of microsatellites

216 uch as neurite outgrowth models of fragile X-chromosome, 15 showed promising activity, suggesting the

217 A DMR was also identified at the chromosome 15 Slc38a4 gene, which encodes a system A ami

218 We identified a QTL on chromosome 15 that contained Csnk1e (63-86 Mb; Csnk1e=79

219 Our results suggest that an area on chromosome 15 that includes DUOX1, DUOX2, and their matu

220 MFD maps to a narrow interval on bovine chromosome 15 that is syntenic to human chromosome 11p12

221 o loci, one on chromosome 8 and the other on chromosome 15, that influence a component of HDL-C-namel

222 In 10/11 translocations involving chromosome 15, the presence of satellite III DNA was obs

223 B cells not expressing eGFP lost one copy of chromosome 15; the eGFP transgene was lost in these cell

224 the NUT (nuclear protein in testis) gene on chromosome 15 to a few other genes, most frequently the

225 ese results narrow our region of interest on chromosome 15 to an area surrounding the gamma-aminobuty

226 ave analyzed loss of heterozygosity (LOH) on chromosome 15 to ascertain its potential involvement in

227 ts; this translocation fuses the PML gene on chromosome 15 to the retinoic acid receptor alpha (RAR a

228 Here we present a finished sequence of human chromosome 15, together with a high-quality gene catalog

229 lymphomas that displayed a high frequency of chromosome 15 trisomy.

230 imprinted region on the proximal long arm of chromosome 15 underlie a complex neurobehavioral disorde

231 ion studies highlighted a human haplotype on chromosome 15 underlying the risk for tobacco dependence

232 ontent and related traits were mapped to pig chromosome 15 using a three-generation intercross betwee

233 The translocation chromosome 15 was found to be paternal in origin.

234 phenotype correlation, a candidate region on chromosome 15 was identified.

235 ly cryptic event: a 77-kilobase segment from chromosome 15 was inserted en bloc into the second intro

236 al association between maternal and paternal chromosomes 15 was observed in human T lymphocytes by th

237 Except on chromosome 15, we observe faster decay of linkage disequ

238 o GFP-expressing controls, cells with LOH at chromosome 15 were morphologically normal and proliferat

239 etic markers within the 15q11-13 interval on chromosome 15 were used for OSA analysis.

240 en one and four copies of the repeat on each chromosome 15, whereas from eight to 20 copies were foun

241 intervals on human chromosome 12q and mouse chromosome 15, which contain the Aqp5 gene.

242 ephrocerebellar syndrome mapped to 700 kb on chromosome 15, which contained a single novel homozygous

243 ulations analyzed showed a nonrandom gain of chromosome 15, which contains the c-myc gene.

244 Half of the associated SNPs were located on chromosome 15, which corresponds with results that other

245 mmon site of retroviral integration on mouse chromosome 15, which includes the genomic structure of t

246 on of small portions of the maternal copy of chromosome 15, which includes the UBE3A gene.

247 It mapped to chromosome 15, while T-STAR mapped to the syntenic regio

248 ges the promyelocytic leukemia gene (PML) on chromosome 15 with the retinoic acid receptor alpha (RAR

249 han 60%), and partial or complete trisomy of chromosome 15, with copy number increases of the c-myc o

250 The gene is positioned on chromosome 15 within bands q24-25.