ライフサイエンスコーパス: chromosome deletion

1 sity (LOH) in developing lymphocytes through chromosome deletion.

2 identified in about 70% of individuals with chromosome deletion.

3 nt(s) of virtually any naturally occurring Y chromosome deletion.

4 was previously shown to be amorphic using a chromosome deletion.

5 1 have short telomeres and elevated rates of chromosome deletions.

6 ency events such as oligonucleotide-mediated chromosome deletions.

7 12 Dm3 mutations were associated with large chromosome deletions.

8 s and high resolution mapping using a set of chromosome deletions.

9 r consequences of "simple" cancer-associated chromosome deletions.

10 ence, and that of the predicted reciprocal X chromosome deletion, among ~218,300 46,XY males of the U

11 Chromosome deletion and microdeletion syndromes account

12 me cancers have a specific tendency to whole-chromosome deletion and regain or to mitotic recombinati

13 ide transposition events but instead yielded chromosome deletion and translocation events involving t

14 To circumvent this problem, we used chromosome deletions and duplications from D. melanogast

15 ed very high rates of aneuploidy, as well as chromosome deletions and duplications.

16 deletion, we examined a panel of men with Y chromosome deletions and known testicular pathologies us

17 a new approach to develop animal models with chromosome deletions, and a potential therapeutic strate

18 Chromosome deletions are the most common genetic events

19 Y chromosome deletions arise frequently in human populatio

20 This approach demonstrates the utility of chromosome deletions as reagents for mapping and charact

21 transcript exon in a previously described X chromosome deletion associated with autism, and the cere

22 In patients with chromosome deletion at the FZD9 locus, aberrant methylat

23 ng evidence for the non-random clustering of chromosome deletion breakpoints with CCG-repeats, and su

24 ved in the mouse, we were able to engineer a chromosome deletion (Df1) spanning a segment of the muri

25 We used chromosome deletion/duplication and P element insertion

26 In most of the common chromosome deletion/duplication syndromes, the rearrange

27 Chromosome deletions, duplications and inversions can be

28 es undergo breakage in mitosis, resulting in chromosome deletions, duplications, and translocations.

29 These studies demonstrate the utility of chromosome deletions for complex trait analysis.

30 ved when the wild-type allele was removed by chromosome deletion from the E2A heterozygous mice, a re

31 Chromosome deletions have several applications in the ge

32 monstrated the effectiveness of Cre-mediated chromosome deletion in the LOH assay for HEB function in

33 unts of 40 000-100 000 per mL, we detected Y-chromosome deletions in leucocyte DNA similar in locatio

34 In the two men in whom Y-chromosome deletions in leucocyte DNA were detected, we

35 The Y-chromosome deletions in these two men are de-novo mutati

36 in 11q23.3, FRA11B, has been shown to cause chromosome deletions in vivo, its expression being assoc

37 Females with partial X-chromosome deletions, in whom this critical locus is del

38 Mice bearing an X chromosome deletion of Hdac6 (Hdac6-/Y) and MTECs from t

39 In addition, duplications of the X chromosome, deletions of chromosomes 9 and 10, and trans

40 In the remaining four cases, X-chromosome deletions prevented interpretation (n = 3), o

41 Thus, the Cre-mediated chromosome deletion provides a new and effective method

42 When present as a single copy in the chromosome, deletions removing as few as two amino acids

43 erm DNA was tested, and it showed the same Y-chromosome deletion seen in leucocytes.

44 were ordered using the P1-derived artificial chromosome deletion series.

45 on of abnormal spermatogenesis in men with Y chromosome deletions suggests that genes important for s

46 In 10-15% of cases, Y chromosome deletions that encompass critical spermatogen

47 hese intervals are defined by interstitial Y-chromosome deletions that impair or extinguish spermatog

48 that aberrant methylation can cooperate with chromosome deletions to silence TSG.

49 y epithelial cell line NOG8 to create random chromosome deletion/translocation.

50 troduce a novel gene-drive strategy termed Y-CHromosome deletion using Orthogonal Programmable Endonu

51 Chromosome deletion was triggered by Cre/loxP-mediated i

52 No Y-chromosome deletions were detected in the fathers of the

53 eveal co-occurrence of ASXL1 mutations and X-chromosome deletions with PHF6(MT).

54 The heterozygous chromosome deletion within the band 22q11 (del22q11) is

55 , five lines of outbred XY(d) females with Y chromosome deletions Y(Del(Y)1Ct)-Y(Del(Y)5Ct) that depl