ライフサイエンスコーパス: chylomicron

1 ysis of triglyceride-rich lipoproteins (e.g. chylomicrons).

2 the unique lipoprotein of the intestine, the chylomicron.

3 that enterocytes assembled and secreted more chylomicrons.

4 accommodate 300-400 nm procollagen fibres or chylomicrons.

5 to 112 nm, 87% exceeding 80 nm, the size of chylomicrons.

6 injected human VLDL and intestinally derived chylomicrons.

7 rs on cells the ability to bind both LPL and chylomicrons.

8 nated the ability of GPIHBP1 to bind LPL and chylomicrons.

9 ys a key role in the lipolytic processing of chylomicrons.

10 ted into a lipid emulsion as a surrogate for chylomicrons.

11 sulting from decreased clearance of VLDL and chylomicrons.

12 ocalization of apolipoprotein B, and loss of chylomicrons.

13 n of duodenal vagal afferents in response to chylomicrons.

14 maintain a range necessary for formation of chylomicrons.

15 proteins nor exclusively secreted as part of chylomicrons.

16 fed a high fat diet, or for the synthesis of chylomicrons.

17 igestion, absorption, and incorporation into chylomicrons.

18 ical properties and metabolic fate of plasma chylomicrons.

19 to be circulating dietary lipid packaged as chylomicrons.

20 cess Cu or Cu chelators impaired assembly of chylomicrons.

21 is incorporated into the surface of nascent chylomicrons.

22 orm mature, very low-density lipoproteins or chylomicrons.

23 sensing to promote assembly and secretion of chylomicrons.

24 (LDL) and very-low-density lipoproteins and chylomicrons.

25 In addition to chylomicrons, absorption of phospholipids, free choleste

26 PCTV-chylomicrons acquire apolipoprotein-AI (apoAI) only afte

27 ipoproteins in much the same way as VLDL and chylomicrons acquire most of their apoCs from HDL.

28 n and were considered fused when their cargo chylomicrons acquired apoAI but docked when they did not

29 Rather, the formation of chylomicrons acts as a signal for the induction of intes

30 tify the appearance of carotenoids in plasma chylomicrons after subjects ingested fresh vegetable sal

31 The rapid entry of chylomicrons after the ingestion of a second meal 5 h af

32 hich could be due to the formation of larger chylomicrons after the MUFA-rich meal.

33 Although chylomicrons also contain retinyl esters (REs), a role o

34 d fat resulted in earlier (>1 h) and sharper chylomicron and [(13)C]fatty acid peaks in plasma than i

35 sulin-sensitive men had similar postprandial chylomicron and chylomicron remnant TG concentrations, b

36 Secretion of lipids by the chylomicron and HDL pathways are dependent on microsomal

37 arifies the functions of key proteins of the chylomicron and the HDL pathways.

38 Lipoprotein lipase (LpL) hydrolyzes chylomicron and very low density lipoprotein triglycerid

39 ced postprandial lipemia via effects on both chylomicron and VLDL metabolism.

40 In a subgroup of the women (n = 7), plasma chylomicrons and 3 subfractions of VLDLs were separated

41 s in plasma including lipid-bound in HDL and chylomicrons and as monomeric and dimeric lipid-free/poo

42 s involved in the intracellular transport of chylomicrons and chylomicron-independent secretion pathw

43 asmic reticulum and are either secreted with chylomicrons and HDLs or stored as cytoplasmic lipid dro

44 effects on lipoprotein metabolism, including chylomicrons and HDLs.

45 The appearance of beta-carotene in chylomicrons and in each VLDL subfraction was lower afte

46 ed delayed clearance of intestinally derived chylomicrons and injected human very low density lipopro

47 Cells transfected with GPIHBP1 bind both chylomicrons and lipoprotein lipase avidly.

48 Chylomicrons and lipoproteins were removed from the plas

49 We measured the production of chylomicrons and localized SR-B1 by immunohistochemistry

50 d cTAGE5 gene products, in the export of pre-chylomicrons and pre-VLDLs from the ER.

51 ake of dietary retinyl ester incorporated in chylomicrons and their remnants and its transfer to the

52 iglycerides are exclusively transported with chylomicrons and this process is critically dependent on

53 sm for the transfer of surface components of chylomicrons and very low density lipoprotein to high de

54 glyceride (TAG)-rich lipoproteins, including chylomicrons and very low density lipoprotein, which is

55 s the CEL(+/+) mice produced primarily large chylomicrons and very low density lipoprotein.

56 accumulation of apoB-48-carrying remnants of chylomicrons and very low density lipoproteins in the pl

57 polipoprotein that dictates the synthesis of chylomicrons and very low density lipoproteins.

58 ipid metabolism, hydrolyzing triglyceride in chylomicrons and very low density lipoproteins.

59 is the essential nonexchangeable protein in chylomicrons and very low-density lipoprotein-derived li

60 TALI, in the endoplasmic reticulum export of chylomicrons and very low-density lipoproteins, but not

61 poprotein B (apoB) dictates the formation of chylomicrons and very low-density lipoproteins, two majo

62 ated with reduced fasting triacylglycerol in chylomicrons and very-low-density lipoproteins (VLDLs) (

63 triglyceride-depleted particles derived from chylomicrons and VLDL that are relatively enriched in ch

64 d that hydrolysis of triglycerides from both chylomicrons and VLDL was significantly reduced in the a

65 intracellular transport of cargo, including chylomicrons and VLDL, may suggest new drug targets for

66 cerol-rich lipoprotein fraction, composed of chylomicrons and VLDLs.

67 Both dietary (chylomicron) and VLDL-triglyceride were cleared across a

68 porated into triglyceride-rich lipoproteins (chylomicrons), and transported in the circulation to var

69 Procollagens, pre-chylomicrons, and pre-very low-density lipoproteins (pre

70 ng very low density lipoproteins (VLDLs) and chylomicrons, and regulates their distribution to periph

71 n B-48, showed that HCV(VLDF) is composed of chylomicron- and VLDL-associated HCV particles; peaking

72 Because chylomicrons are 250 nm in average diameter and lipid ab

73 Chylomicrons are transported from the endoplasmic reticu

74 These observations were seen using chylomicrons as well as the synthetic lipid emulsion Int

75 deficiency in the formation and secretion of chylomicrons, as supported by the significantly less apo

76 de transfer protein (Mttp-IKO), which blocks chylomicron assembly and impairs intestinal lipid transp

77 features for MTTP involvement in intestinal chylomicron assembly and secretion and suggest that hepa

78 Chylomicron assembly and secretion is increased by the e

79 It is involved in chylomicron assembly and secretion, protection from athe

80 of enzymes involved in lipid absorption and chylomicron assembly are greater in XX male and female m

81 Chylomicron assembly begins with the formation of primor

82 ritical role in phospholipid homeostasis and chylomicron assembly in enterocytes.

83 blation studies showed that MTP function and chylomicron assembly is essential for the absorption of

84 at alpha-T absorption is highly dependent on chylomicron assembly processes.

85 ys of metabolic regulation following blocked chylomicron assembly, including shifts in BA signaling a

86 In addition to chylomicron assembly, intestinal cells have been shown t

87 portant roles in lipid metabolism, including chylomicron assembly, reverse cholesterol transport, and

88 ys a role in intestinal lipid absorption and chylomicron assembly.

89 le source of cholesterol esters for VLDL and chylomicron assembly.

90 poprotein lipase hydrolyses triglycerides in chylomicrons at the luminal surface of the capillaries i

91 nge, soybean oil was linearly related to the chylomicron AUC and Cmax values for alpha-carotene, lyco

92 bean oil, there was a linear increase in the chylomicron AUC and Cmax values for beta-carotene.

93 il, there were minor linear increases in the chylomicron AUC for lutein and alpha- and total tocopher

94 g oil, the interindividual rank order of the chylomicron AUCs was consistent across the carotenoids a

95 sing cells bind lipoprotein lipase (LPL) and chylomicrons avidly.

96 the acidic domain of GPIHBP1 blocked LPL and chylomicron binding to GPIHBP1-expressing cells.

97 yaspartate and polyglutamate blocked LPL and chylomicron binding to GPIHBP1.

98 ntestine-specific inhibitors of MTP decrease chylomicron biogenesis and improve insulin sensitivity i

99 The intracellular steps of chylomicron biogenesis and transport from the Endoplasmi

100 termined that lipin enzymes are critical for chylomicron biogenesis, through regulation of membrane p

101 for enterocyte phospholipid homeostasis and chylomicron biogenesis.

102 activation of LXR reduces the production of chylomicrons by a mechanism dependent on the apical loca

103 ry low density lipoproteins by the liver and chylomicrons by the intestine.

104 " LPL can mediate the acquisition of nascent chylomicrons by the placenta, although less efficiently.

105 Triglyceride-rich lipoproteins, primarily chylomicrons, can contribute to plasma free fatty acid (

106 The outcome variables were the chylomicron carotenoid and fat-soluble vitamin area unde

107 LCn3s reduced postprandial chylomicron cholesterol and VLDL apolipoprotein B-48.

108 cholesterol of up to 25 and 60% reduction in chylomicron cholesterol content are seen with a 10-mg do

109 re is an increasing tendency for large VLDL, chylomicrons, chylomicron remnants and small, dense LDL

110 uimolar amounts but have opposite effects on chylomicron (CM) production, with GLP-1 significantly re

111 he aim was to determine whether fed VLDL and chylomicron (CM) triacylglycerol (TAG) production rates

112 sm, we investigated uptake and hydrolysis of chylomicron (CM)-retinyl esters (RE) by rat hepatoma (Mc

113 Chylomicrons (CM) can bind endotoxin (lipopolysaccharide

114 n of very-low-density lipoprotein (VLDL) and chylomicrons (CM) was investigated in the ZDF rat model

115 carried in low density lipoprotein (LDL) and chylomicrons (CMs) taken up into the tissues through the

116 Very-low-density lipoprotein (VLDL) and chylomicrons (CMs) transport triacylglycerol (TAG) to pe

117 n-silico model for prediction of affinity to chylomicrons (CMs), and then synthesized.

118 There is evidence that chylomicron components are involved in this lipid transd

119 RLPs derived from chylomicrons contain apoB48, while those derived from VL

120 Chylomicrons containing newly absorbed retinyl esters ar

121 s (RLPs), derived by lipolysis from VLDL and chylomicrons, contribute to this residual risk.

122 loped fatty liver disease, because of direct chylomicron deposition via misconnected portal vein and

123 erived fatty acid and a non-CD36 process for chylomicron-derived fatty acid uptake.

124 This was especially so for chylomicron-derived fatty acids, representing the direct

125 omicron production, mechanisms that underlie chylomicron dysregulation, and potential avenues for fut

126 in rodent models of obesity and postprandial chylomicron excursion to validate DGAT-1 inhibition as a

127 ved from the lipid emulsion (a surrogate for chylomicrons; extraction fraction 31 +/- 4%, P < 0.005 v

128 oscopy results and confirmed by the use of a chylomicron flow blocker, cycloheximide, that prevented

129 ified and packaged into triacylglycerol-rich chylomicrons for bodily distribution.

130 ly synthesized triacylglycerols into nascent chylomicrons for secretion.

131 droplets or incorporated into lipoproteins (chylomicrons) for secretion.

132 CT (peanut oil), or LCT plus an inhibitor of chylomicron formation (Pluronic L81).

133 The key steps appear to be related to chylomicron formation and secretion and are closely coup

134 CD36 may play an important role in chylomicron formation and secretion and may also facilit

135 fatty acids (FA) and cholesterol uptake, and chylomicron formation and secretion.

136 iacylglycerol resynthesis in enterocytes for chylomicron formation and secretion.

137 ed in triglyceride synthesis and storage and chylomicron formation have altered expression, and large

138 etary fatty acid and cholesterol for optimal chylomicron formation, whereas CD36-independent mechanis

139 lpha activation in the enterocyte on HDL and chylomicron formation.

140 urve (AUC) and maximum content in the plasma chylomicron fraction (Cmax).

141 , retinyl esters are also present within the chylomicron fraction obtained from Lrat-/- mice.

142 om labeled [(13)C(1)]palmitate in the plasma chylomicron fraction, and [(13)C(1)]palmitate oxidation

143 ene supplements, measurement of postprandial chylomicron fractions after consumption of a beta-carote

144 acid complex, lipoprotein, protein-free, and chylomicron fractions with no need of salt or sugar dens

145 icrons through the enterocyte is the exit of chylomicrons from the endoplasmic reticulum in prechylom

146 iers that are essential for the transport of chylomicrons from the endoplasmic reticulum to the Golgi

147 that facilitates the lipolytic processing of chylomicrons has never been clearly defined.

148 ms for post-Golgi transport and secretion of chylomicrons have not been identified.

149 dietary retinol primarily as free retinol in chylomicrons; however, retinyl esters are also present w

150 s after their ingestion, and release them in chylomicrons in response to oral glucose, sham feeding,

151 There is a rapid appearance of chylomicrons in the circulation carrying fat ingested wi

152 After injection of these labeled chylomicrons in the different mice, chylomicron TG uptak

153 the appearance of the carotenoids in plasma chylomicrons increased relative to that after ingestion

154 intracellular transport of chylomicrons and chylomicron-independent secretion pathways are expected

155 he retinyl esters are then incorporated into chylomicrons, intestinal lipoproteins containing other d

156 ipoprotein lipase-generated fatty acids from chylomicrons into the plasma free fatty acid (FFA) pool

157 lutein concentration was measured in plasma chylomicrons isolated at regular time intervals over 8 h

158 4-RA method, which controls for variation in chylomicron kinetics in vivo and RE recovery during anal

159 n hepatocyte cell line HepG2, incubated with chylomicrons, led to increased accumulation of REs in en

160 treatment inhibited the secretion of larger chylomicron-like lipoproteins without affecting total ch

161 ease and Anderson disease selectively retain chylomicron-like particles within membrane-bound compart

162 rporates and rapidly secretes dietary fat as chylomicrons (lipoprotein particles comprising triglycer

163 fferences in postprandial serum LPS, LBP, or chylomicron LPS concentrations between acute RW, DRW, or

164 LPS and LBP concentrations and postprandial chylomicron LPS concentrations were measured.

165 ion of SNPs associated with the postprandial chylomicron lutein response (0-8-h area under the curve)

166 ned most of the variance in the postprandial chylomicron lutein response.

167 Postprandial chylomicron lutein responses measured after the 2 meals

168 Postprandial chylomicron lutein responses to meals were very variable

169 of the dietary vitamin A is absorbed via the chylomicron/lymphatic route, it is also clear that under

170 By analogy with procollagen, chylomicrons may drive the formation of endoplasmic reti

171 osed roles in vascular disease, satiety, and chylomicron metabolism, there is no known structural bas

172 ion was used as a surrogate for the study of chylomicron metabolism.

173 SNPs in 15 genes related to both lutein and chylomicron metabolism.

174 the membrane, and their conversion to large chylomicrons occurs in the lumen of the smooth endoplasm

175 ol, apolipoprotein B-48 (apoB-48; reflecting chylomicrons of intestinal origin), free fatty acids (FF

176 n meal would be transferred rapidly from the chylomicrons of the blood into human milk.

177 data suggest that in the intestinal mucosa, chylomicrons or their products release endogenous CCK wh

178 er characterized by the inability to produce chylomicrons or very low-density lipoproteins, with the

179 could be explained by changes in exogenous (chylomicron) or endogenous (VLDL) lipid metabolism and w

180 may play an inhibitory or modulatory role in chylomicron packaging in humans.

181 /L; P=0.03) very low-density lipoprotein and chylomicron particle number in addition to triglyceride

182 IV (apoA-IV) is a major component of HDL and chylomicron particles and is involved in reverse cholest

183 Blood sampling occurred intermittently, and chylomicron particles S(f) >400 TAGs were analyzed by ga

184 ing the packaging of additional core TG into chylomicron particles.

185 sociation of apolipoprotein B48 with nascent chylomicron particles.

186 erol, and vitamin E are absorbed through the chylomicron pathway, a significant amount of these lipid

187 to LCTs, and in vitro assays indicated that chylomicrons prevent basophil activation.

188 role for CEL, namely the promotion of large chylomicron production in the intestine.

189 Because chylomicron production is most efficient proximally we e

190 in-depth understanding of the regulation of chylomicron production may provide leads for the develop

191 Elevated chylomicron production rate contributes to the dyslipide

192 In this review we discuss the regulation of chylomicron production, mechanisms that underlie chylomi

193 6-alpha-tocopherol AUC0- t final in both the chylomicron (r = -0.46 to -0.52) and VLDL (r = -0.49 to

194 The complexity of VLDL and chylomicron remnant clearance was exemplified by the stu

195 In the liver, LRP1 serves as a chylomicron remnant receptor and also participates in th

196 ated protein-1 (LRP1) is known to serve as a chylomicron remnant receptor in the liver responsible fo

197 men had similar postprandial chylomicron and chylomicron remnant TG concentrations, but insulin-resis

198 ation in macrophages were investigated using chylomicron remnant-like particles (CRLPs) containing th

199 It has been proposed that in the liver, chylomicron remnants (lipoproteins carrying dietary lipi

200 andial lipemia and the biological effects of chylomicron remnants and lipolysis products will be revi

201 asing tendency for large VLDL, chylomicrons, chylomicron remnants and small, dense LDL to fall on tre

202 nding and internalization of (125)I-labelled chylomicron remnants derived from palm, olive, corn, or

203 results suggest that antioxidants carried in chylomicron remnants enhance lipid accumulation in macro

204 The effects of protection of chylomicron remnants from oxidation on their uptake and

205 ted by diet composition; (c) the presence of chylomicron remnants in the fasting state on LF/HC diets

206 dings demonstrate that the hepatic uptake of chylomicron remnants is influenced both by the fatty aci

207 To study this, chylomicron remnants labeled with a fluorescent dye were

208 rom normal mice, there was clustering of the chylomicron remnants on the cell surface in the space of

209 Antioxidants carried in chylomicron remnants therefore may promote the developme

210 Clearance of VLDL and chylomicron remnants was hampered, leading to accumulati

211 e. nonesterified unsaturated fatty acids and chylomicron remnants) that induced FGF21 gene expression

212 ns, i.e. low density lipoproteins (LDLs) and chylomicron remnants, are atherogenic.

213 low-density lipoprotein, lipoprotein (a), or chylomicron remnants.

214 ensity lipoprotein (IDL) comprising VLDL and chylomicron remnants.

215 n of LpL activity, and impaired clearance of chylomicron remnants.

216 mic very low density lipoproteins as well as chylomicron remnants.

217 osed cholesteryl ester and triglyceride-rich chylomicron remnants.

218 rotein supplement decreased the postprandial chylomicron response compared with casein in persons wit

219 Patients with chylomicron retention disease and Anderson disease selec

220 Sar1b is defective in chylomicron retention disease and Anderson disease, two

221 The identification of genetic mutations in chylomicron retention disease indicates that Sar1b may p

222 ects, cranio-lenticulo-sutural dysplasia, or chylomicron retention disease, but mechanisms to enlarge

223 ever, it is not known why some patients with chylomicron retention disorder develop hepatic steatosis

224 1B component of this machinery is mutated in chylomicron retention disorder, indicating that this Sar

225 The fractional and absolute transfer of chylomicron retinyl esters (CM-REs), retinol bound to re

226 role in the hydrolysis of newly-endocytosed, chylomicron retinyl esters in both neutral and acidic me

227 The fatty acyl composition of these (chylomicron) retinyl esters suggests that they are synth

228 dial triacylglycerol content and size of the chylomicron-rich fraction, plasma kinetics of [(13)C]fat

229 an important role for DENND5B in post-Golgi chylomicron secretion and a subsequent influence on body

230 Cd36 null (Cd36(-/-)) mice exhibit impaired chylomicron secretion but no overall lipid absorption de

231 stinal absorption of lipids, but its role in chylomicron secretion in human beings is unknown.

232 Chylomicron secretion is subject to regulation by variou

233 Chylomicron secretion was reduced dramatically in vivo,

234 control of dietary fatty acid absorption and chylomicron secretion.

235 anes to intracellular organelles and reduced chylomicron secretion.

236 ene in Golgi to plasma membrane transport of chylomicron secretory vesicles.

237 emulsified fat resulted in a 3-fold greater chylomicron size (218 +/- 24 nm) compared with the sprea

238 There were no significant differences in chylomicron size between the 2 groups for either meal, b

239 mbined there was a significant difference in chylomicron size between the SFA- and MUFA-rich meals (P

240 ot appear necessary for initial formation of chylomicron-sized lipid particles in the endoplasmic ret

241 In contrast, clearance of chylomicron-sized n-3 TG emulsions relies on LPL to a ve

242 Removal of chylomicron-sized n-6 TG emulsions is modulated by lipop

243 ntained large cytoplasmic TG droplets and no chylomicron-sized particles within the secretory pathway

244 ct that GPIHBP1 binds lipoprotein lipase and chylomicrons suggest that GPIHBP1 is a key platform for

245 stinal lipid absorption and mobilization and chylomicron synthesis and secretion are highly regulated

246 ed intestinal triacylglycerol absorption and chylomicron synthesis and secretion in DGAT1-deficient (

247 s and 3 females) to investigate the kinetics chylomicron synthesis and the effect of sensory exposure

248 Impaired chylomicron synthesis in lipin 2/3 deficiency could be r

249 of Noc(-/-) mice on diets that challenge the chylomicron synthesis pathway result in significant redu

250 distal small intestine, a tissue involved in chylomicron synthesis.

251 onal roles of ACAT1 and ACAT2 in the VLDL or chylomicron synthesis/assembly process.

252 Loss of CD36 did not alter either chylomicron TG or retinyl ester uptake.

253 sed plasma TG levels associated with reduced chylomicron TG uptake into BAT and lung.

254 labeled chylomicrons in the different mice, chylomicron TG uptake was reduced by approximately 70% a

255 ic tracers showed that the difference was in chylomicron-TG extraction.

256 gher in men driven by change in postprandial chylomicron-TG level but that increase in 6-h postprandi

257 plasma NEFA and VLDL-TG pools compared with chylomicron-TG.

258 rt-term ingestion of olive oil produced more chylomicrons than did the other dietary oils, which may

259 ration of GLP-2 to men causes the release of chylomicrons that comprise previously synthesized and st

260 ge of bulky cargo, including procollagen and chylomicrons, that is sensitive to adaptor function in i

261 In chylomicrons, the area under the concentration-versus-ti

262 nism of inhibition involves the formation of chylomicrons, the essential role of the apolipoprotein a

263 Before secretion on chylomicrons, these lipids are reesterified into TG, pri

264 te mesenteric lymph flow and are absorbed in chylomicrons through mesenteric lymph.

265 The rate-limiting step in the transit of chylomicrons through the enterocyte is the exit of chylo

266 esses that mediate the transport of HDLs and chylomicrons through the lymphatic vasculature.

267 ron transport vesicles (PCTV) that transport chylomicrons to the cis-Golgi.

268 vage and that the Noc(-/-) mice have reduced chylomicron transit into the plasma following the ingest

269 the enterocyte is the generation of the pre-chylomicron transport vesicle (PCTV) from the endoplasmi

270 o bind to intestinal ER and generate the pre-chylomicron transport vesicle (PCTV).

271 uires ATP to initiate the budding of the pre-chylomicron transport vesicle from intestinal endoplasmi

272 ther ER-derived vesicles such as PTV and pre-chylomicron transport vesicle.

273 of fat in a meal can modify the absorption, chylomicron transport, and further metabolic handling of

274 entrations (P = 0.013), a more rapid rise in chylomicron triacylglycerol concentrations (P = 0.04), a

275 Chylomicron-triacylglycerol disposal was estimated from

276 Chylomicron-triacylglycerol-derived [(13)C(1)]palmitate

277 3)C]palmitate was added to the meal to label chylomicron-triacylglycerol.

278 Further, HLS patients had lowered storage of chylomicron-triacylglycerols (0.74 +/- 0.38 compared wit

279 impair postprandial disposal and storage of chylomicron-triacylglycerols.

280 between time 90 and 120 min driven by higher chylomicron-triglyceride (TG) levels.

281 However, this was minor in comparison with chylomicron-triglyceride fatty acids.

282 ed fatty acids derived from the spillover of chylomicron-triglyceride in the fasted and fed states, a

283 gh with greater fractional extraction of the chylomicron-triglyceride.

284 Metabolism of chylomicron triglycerides in visceral fat may be an impo

285 clude dietary FA that clear to the liver via chylomicron uptake, FA synthesized de novo in the liver

286 h (AUC0- t final) in lipoprotein fractions [chylomicron, very-low-density lipoprotein (VLDL), LDL, h

287 pholipid (PL) as lipoproteins, mostly in the chylomicron/very low density lipoprotein (VLDL) density

288 rides is the first and rate-limiting step in chylomicron/very low density lipoprotein clearance at th

289 However, this build-up of triglyceride-rich chylomicrons/very low density lipoproteins is not due to

290 genesis of very low-density lipoproteins and chylomicrons via the transfer of neutral lipids and the

291 In group 1, chylomicron, VLDL, IDL, and HDL cholesterol levels predi

292 n triglyceride-rich lipoproteins (containing chylomicrons, VLDL, and remnants) exhibit more complex k

293 nces basolateral TG, CE, and PL secretion in chylomicron/VLDL particles.

294 PRAP1 is detectable in chylomicron/VLDL-rich plasma fractions, suggesting that

295 the appearance of the carotenoids in plasma chylomicrons was higher after the ingestion of salads wi

296 pha-carotene, beta-carotene, and lycopene in chylomicrons was negligible.

297 Chylomicrons were isolated by ultracentrifugation, and c

298 Endogenously labeled mouse chylomicrons were produced by tamoxifen treatment of bet

299 Our data suggest that chylomicrons, which vastly exceed the size of typical CO

300 s of fasting plasma triacylglycerols in both chylomicron (x + SE: 100.3 +/- 49.5 compared with 29.2 +