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1 upregulated late, when most cells were fully ciliated.
2 y motility, and airways fail to become fully ciliated.
3 estor of bilaterians was probably a benthic, ciliated acoelomate worm with a single opening into an e
6 or (CFTR) gene that is normally expressed in ciliated airway epithelial cells and the submucosal glan
7 e how to adapt the protocol to expose living ciliated airway epithelial cells to smoke generated by e
10 consisting mostly of a lumen layer of multi-ciliated and a layer of Keratin-5-positive basal cells.
11 o goblet and club cells, and was absent from ciliated and basal cells as detected via immunohistochem
12 termediate cells, reduced proportions of SAE ciliated and basal cells, markedly abnormal SAE and alve
13 suggest a role for beta-catenin in basal to ciliated and basal to Clara-like cell differentiation.
14 that HMC induced activation of LKB1 in both ciliated and deciliated cells in vitro, resulting in the
16 ing their 3D culture characteristics such as ciliated and goblet cells, and ion channel function.
19 is supported by the extensive development of ciliated and muscular structures including the presence
20 ) RNP, allow rapid entry into cultured human ciliated and non-ciliated epithelial cells and mouse air
21 isted of a layered epithelium structure with ciliated and nonciliated cells on its apical surface.
22 re-2009 seasonal A(H1N1) virus infected both ciliated and nonciliated cells, whereas a highly pathoge
23 cific H2Bub1, we performed ChIP-seq of mouse ciliated and nonciliated tissues and showed tissue-speci
24 n to noncontiguous or small clumps of apical ciliated and occasional nonciliated epithelial cells, ap
25 axis globally, but the nature of this cue in ciliated and other epithelia remains poorly understood.
26 thelium of the lung is composed of polarized ciliated and secretory cells maintained by basal stem/pr
27 asal cells, the stem/progenitor cells of the ciliated and secretory cells that are central to pulmona
28 dostratified epithelium of the lung contains ciliated and secretory luminal cells and basal stem/prog
29 n lung are lined by an epithelium made up of ciliated and secretory luminal cells and undifferentiate
30 ruent with culture data, SARS-CoV-2-infected ciliated and type 2 pneumocyte cells in airway and alveo
31 nd release a majority of their HA onto their ciliated apical surfaces to form a heavy chain hyalurona
35 m the stomodeal region of the oral ectoderm, ciliated band cells and cells from the endoderm/ectoderm
36 We also observe a reduction in the number of ciliated beta-cells along with misregulated ciliary/basa
37 ors (GNPs) from which they derive, are often ciliated beyond G1 into S phase, and the presence of the
40 clusion bodies (ICI) have been identified in ciliated bronchial epithelium of Kawasaki disease (KD) p
42 e higher in WD-PBECs, coincident with higher ciliated cell contents, cell sloughing, and slightly com
45 tment, while it's expression correlated with ciliated cell development and decreased along with incre
46 epithelial cell fate by inhibiting Clara and ciliated cell differentiation and activating Uchl1, a ma
47 airway epithelial cell fate, Fgf10 prevents ciliated cell differentiation and promotes basal cell di
48 ckout of CDHR3 in human AECs did not prevent ciliated cell differentiation but was associated with a
50 l cell fate at the expense of a proximal and ciliated cell fate, whereas WNT signaling promoted a pro
53 e grown to goblet or normally differentiated ciliated cell phenotype at air-liquid interface in the p
55 rplasia is shown to stem from a novel mucous ciliated cell state, as well as goblet cell hyperplasia.
56 ypes, including a previously uncharacterized ciliated cell type, during four major phases of endometr
57 eceptors and to the transition zone in other ciliated cell types and that cilia are present in these
58 theoretical framework to conduct a census of ciliated cell types, create structural maps, and resolve
59 sitting atop the PCF is pushed along by the ciliated cell's beating cilia, the PCF and its virus con
61 tein kinase (PKA) subunits expressed under a ciliated cell-specific promoter) in response to increase
63 y human airway cultures establish NEK10 as a ciliated-cell-specific kinase whose activity regulates t
66 By contrast, Il-6 null mice regenerate fewer ciliated cells and an increased number of secretory cell
68 summarize current knowledge regarding airway ciliated cells and cilia, how they function to maintain
69 on in both cultures was restricted to apical ciliated cells and occasional nonciliated cells but not
70 basal cell fate by driving the generation of ciliated cells and preventing the production of Clara-li
71 oid morphogenesis and the differentiation of ciliated cells and reduces the expression of both notch
72 e human influenza viruses primarily infected ciliated cells and replicated efficiently, whereas a hig
73 hat develop into surface mucus secretory and ciliated cells and then contrasts these to the unique sp
75 n of asymmetry-called Kupffer's vesicle (KV)-ciliated cells are asymmetrically positioned along the a
76 ial cells, airway club cells and respiratory ciliated cells as potential reservoirs of the SARS-CoV-2
77 e human airway epithelium is the presence of ciliated cells bearing motile cilia, specialized cell su
78 it remained unclear how the distribution of ciliated cells becomes asymmetric during KV development.
79 ear and unambiguous evidence to suggest that ciliated cells can become goblet cells using immunoelect
81 ective ablation of CTNNB1 from the oviductal ciliated cells did not affect embryo transport, possibly
85 reduction of KIF11 expression, the number of ciliated cells in asynchronously growing populations was
88 ngth and with a reduction of the fraction of ciliated cells in Npc1-deficient mouse brains and the hu
90 or different functions: basal, secretory and ciliated cells in the conducting airways and type II and
94 ion and motility specifically in a subset of ciliated cells of the mouse COA (posterior notochord, PN
95 ti-IL-33 also re-established the presence of ciliated cells over mucus-producing cells and decreased
98 Ectopic coexpression of PCARE and WASF3 in ciliated cells results in the remarkable expansion of th
99 ike epithelium with basal cells and immature ciliated cells surrounded by smooth muscle and myofibrob
100 urprisingly, we also found a region of multi-ciliated cells that line the posterior dorsal pole of th
101 only assembled in terminally differentiating ciliated cells through the acentriolar pathway to trigge
103 ucted an RNAi-based screen in Drosophila non-ciliated cells to test for cilium-independent loss-of-fu
104 orescence staining showed that the number of ciliated cells was significantly decreased by the flavor
106 ed to identify the location and cell type of ciliated cells with the use of antibodies specific for c
107 nstrate a direct conversion of club cells to ciliated cells without proliferation, meeting a conserva
108 almost exclusively expressed in a subset of ciliated cells, a strong indicator of cilia-related func
109 infectious virus, a more pronounced loss of ciliated cells, and a reduced thickness of the epithelia
110 KIAA0556 is expressed almost exclusively in ciliated cells, and the worm and human KIAA0556 proteins
111 rn that appeared to originate primarily with ciliated cells, but lateral spread from the base of the
112 cells, mucus-secreting goblet cells, motile ciliated cells, cystic fibrosis transmembrane conductanc
113 , structural and functional abnormalities of ciliated cells, decreased number of secretoglobin (SCGB1
115 addition to using this homology to attach to ciliated cells, it activates human neonatal regulatory B
116 s required for TZ assembly in all Drosophila ciliated cells, it also regulates basal-body growth and
117 and lineage differentiation (ss-tubulin IV+ ciliated cells, MUC5AC+ goblet cells, p63 + basal cells)
120 t CEP290 localizes to the transition zone in ciliated cells, precisely to the region of Y-linkers bet
122 ss of club cells, with a concomitant gain in ciliated cells, under homeostatic conditions without inc
123 amphioxus frontal eye is composed of simple ciliated cells, unlike vertebrate rods and cones, which
124 , in a model of ectopic expression of LAT in ciliated cells, we show that GMAP210 tethering activity
125 GAS2L2 is abundant at the apical surface of ciliated cells, where it localizes with basal bodies, ba
126 (alpha2,6-linked) receptors predominated on ciliated cells, whereas avian-like (alpha2,3-linked) rec
127 ylases ccp2, ccp5, and ccp6 are expressed in ciliated cells, whereas ccp1 expression is restricted to
154 sed in basal, intermediate, club, mucus, and ciliated cells; 3) ACE2 is upregulated in the SAE by smo
156 s inhibited migration and invasion in normal ciliated cholangiocytes through a P2Y11 receptor and liv
159 velopment, Notch signaling occurs within the ciliated, differentiating cells of the first few supraba
160 rentiated basal cells and restricts basal-to-ciliated differentiation, and we present evidence that N
161 component of the horizontal velocity at the ciliated edge generates a 2D fluid velocity field with a
166 istinct, neuron-type-specific elaboration of ciliated endings of different olfactory neuron types in
168 se hydrocephalus or prevent the formation of ciliated ependymal cells but caused defects in their dif
170 (SVZ) stem cell niche is comprised of multi-ciliated ependymal cells that line the brain ventricular
172 identified a role for Lgl2 in development of ciliated epithelia in Kupffer's vesicle, which directs l
174 dy, we have defined such a program for multi-ciliated epithelial cells (MCCs), a cell type critical f
175 d entry into cultured human ciliated and non-ciliated epithelial cells and mouse airway epithelia.
178 Infectious bronchitis virus (IBV) infects ciliated epithelial cells in the chicken respiratory tra
179 ated with polyA-tailed RNA species in murine ciliated epithelial cells of the inner medullary collect
181 rise from the collective actions of a set of ciliated epithelial cells, each independently sensing an
182 mprising the majority of the cells, includes ciliated epithelial cells, newly identified lipophil cel
185 ry response and bacterial adherence to human ciliated epithelial cultures and markedly increased viru
186 infect the chicken respiratory tract via the ciliated epithelial layer of the trachea, some strains c
194 d tissue M cells appear to be generated from ciliated Foxj1(+)PGRP-S(+) cells, indicative of a possib
196 t, CaMK-II suppression results in additional ciliated hair cells and altered levels of Delta-Notch si
199 ically, we found that LZTFL1 is expressed in ciliated human bronchial epithelial cells (HBECs) and it
202 uch coordination is achieved, we studied the ciliated larvae of Platynereis dumerilii, a marine annel
203 population in the proximal airways that are ciliated-like, but transcriptionally and phenotypically
204 Transgenic reintroduction of Ptk7 in motile ciliated lineages prevents scoliosis in ptk7 mutants, an
205 planktonic predators also have sophisticated ciliated locomotion, behaviour and distinct development.
206 d 7 of these 22 genes with expression in the ciliated LR organizer (gastrocoel roof plate), a marked
207 er monocytes and macrophages (LysM/STAT1) or ciliated lung epithelial cells (FoxJ1/STAT1) deleted wer
209 ytes (neurosensory cells) and in statocytes (ciliated mechanosensory cells) of C. hemisphaerica, a me
212 Here, we show that pheromones sensed by ciliated neurons in the Caenorhabditis elegans nose alte
214 m or associated with the apical membranes of ciliated, nonciliated, and mucin-secretory goblet cells.
215 olfactory epithelium is mostly populated by ciliated olfactory sensory neurons (OSNs) and surroundin
216 amb1a functions in Kupffer's vesicle (KV), a ciliated organ analogous to the mouse node, to control t
217 LR) asymmetry results from the activity of a ciliated organ functioning as the LR Organizer (LRO).
218 c fluid flow in the evolutionarily conserved ciliated organ of asymmetry (COA) and play a fundamental
219 h cell-autonomous functions in the zebrafish ciliated organ of asymmetry, Kupffer's vesicle (KV), inc
220 s7 knockdown both disrupt the formation of a ciliated organ, the Kupffers vesicle (KV), but do not di
227 receptor, was highly expressed in zebrafish ciliated organs and regulated ciliary structure and func
228 In zebrafish, tuba was expressed in multiple ciliated organs, and, accordingly, tuba start and splice
229 nockout, we also observed defects in several ciliated organs, including the brain (hydrocephalus), he
231 cells and is associated with a reduction in ciliated, ostensibly proliferation-suppressed beta cells
232 s highlighted a significantly lower level of ciliated patient cells compared to controls, confirming
235 he development, function, and maintenance of ciliated photoreceptors, we generated a pan-retina knock
243 zoal grazing due to the higher inhibition of ciliated protozoa as compared to bacteria when exposed t
248 a (Escherichia coli (E. coli)) as a prey and ciliated protozoan (Paramecium caudatum) as a predator o
249 otably, unlike the heart-shaped structure of ciliated protozoan Oxytricha nova TEBPalpha-beta complex
251 ciated with the photoreceptor protein of the ciliated protozoan Stentor coeruleus (Heterotrichea; Ste
253 process of programmed DNA elimination in the ciliated protozoan Tetrahymena Here, we show that the he
254 to detect and semi-quantify these NPs in the ciliated protozoan Tetrahymena thermophila as a model aq
257 , its presence in Tetrahymena thermophila, a ciliated protozoan with seven sexes or mating types that
259 utionary analysis of centromeric histones in ciliated protozoans, a group that only undergoes asymmet
262 y epithelial characteristics as evidenced by ciliated pseudostratified columnar epithelium with goble
264 t infiltration than everolimus and preserved ciliated pseudostratified columnar respiratory epitheliu
266 generated are cholinergic, peptidergic, and ciliated putative proprioceptors which integrate into ma
267 ensitive to light has been the presence of a ciliated putative sensory cell in the close vicinity of
270 rate Ccdc135 (E = 6e-78) highly expressed in ciliated respiratory epithelia and sperm, and to FAP50 (
279 the epidermis, intestine, body wall muscle, ciliated sensory neurons and touch receptor neurons - wh
280 lution transcriptome profile of a subtype of ciliated sensory neurons isolated from adult animals rev
281 for the undulation propagation and that the ciliated sensory neurons participated in the joint selec
282 w here that specific Caenorhabdidits elegans ciliated sensory neurons shed and release ECVs containin
283 OFIP protein, whose sequence is conserved in ciliated species, associates with centrosome/centriole a
285 at a transient left-right organizer (LRO), a ciliated structure where cilia play a crucial role in br
286 a conserved and specific role in particular ciliated structures, most consistently in ciliary bands.
290 EC subsets, such as chemokine-expressing and ciliated TEC, which warrant further characterisation.
291 s, and cilia motility is lost in a number of ciliated tissues along with a reduction in the number of
292 x2 in Xenopus is expressed preferentially in ciliated tissues, including neural tube, gastrocoel roof
293 alis We discover that Dyrk1a is expressed in ciliated tissues, localizes to ciliary axonemes and basa
294 ex members are primarily expressed in motile ciliated tissues, suggesting a conserved function in mam
298 o and in vitro yielded basal, goblet, Clara, ciliated, type I and type II alveolar epithelial cells.