ライフサイエンスコーパス: cinnamate

1 f ammonia from l-phenylalanine to give trans-cinnamate.

2 gnal response without an exogenous source of cinnamate.

3 rhizobia grown in the presence or absence of cinnamate.

4 nzyl group and 4-methoxy substitution in the cinnamate.

5 e transport inhibitor, alpha-cyano-4-hydroxy cinnamate.

6 ntents of ethyl esters of branched acids and cinnamates.

7 other top two compounds epigallocatechin 3-O-cinnamate (- 10.3 kcal/mol), and epicatechin gallate (-

8 alpha- to (R)-beta-phenylalanine, making (E)-cinnamate (~10%) as a byproduct at steady state.

9 By contrast, when the cinnamate 4-hydroxylase (C4H) promoter was used to drive

10 erefore may be rapidly channeled through the cinnamate 4-hydroxylase (C4H) reaction to 4-coumaric aci

11 ree CYP450s involved in lignin biosynthesis: CINNAMATE 4-HYDROXYLASE (C4H), p-COUMARATE 3-HYDROXYLASE

12 with the next enzyme, the endomembrane-bound cinnamate 4-hydroxylase (C4H), to facilitate channeling,

13 Two different full-length cDNAs for cinnamate 4-hydroxylase (C4H1 and C4H2) were isolated fr

14 Cinnamate 4-hydroxylase (C4H; CYP73A) is a cytochrome P4

15 (phenylalanine ammonia-lyase1 [PAL1], PAL2, cinnamate 4-hydroxylase [C4H], 4-coumarate:CoA ligase1 [

16 While Arabidopsis cinnamate 4-hydroxylase adopts conventional NADPH-cytoch

17 by Phe supply and differential modulation of cinnamate 4-hydroxylase and p-coumarate 3-hydroxylase ac

18 By contrast, transcript levels for both cinnamate 4-hydroxylase and p-coumarate 3-hydroxylase we

19 Furthermore, a trans-cinnamate 4-hydroxylase mutant, which is impaired in the

20 n differed in plants downregulated in either cinnamate 4-hydroxylase or phenylalanine ammonia-lyase.

21 cs in which F5H expression was driven by the cinnamate 4-hydroxylase promoter was almost entirely syr

22 C4H1 is most homologous to a cinnamate 4-hydroxylase sequence from French bean (Phase

23 further characterized as a new inhibitor of CINNAMATE 4-HYDROXYLASE, a key enzyme of the phenylpropa

24 ript levels for phenylalanine ammonia lyase, cinnamate 4-hydroxylase, p-coumarate 3-hydroxylase, 4-co

25 an enhanced expression of the gene encoding cinnamate 4-hydroxylase, which appears to be the princip

26 ministering 100 microM alpha-cyano-4-hydroxy-cinnamate (4-CIN), a dose that blocks the neuronal monoc

27 rmacological and genetic approaches to block CINNAMATE-4-HYDROXYLASE (C4H) functionality in Arabidops

28 Cinnamate-4-hydroxylase (C4H) is the first Cyt P450-depe

29 ng on piperonylic acid (PA), an inhibitor of CINNAMATE-4-HYDROXYLASE (C4H) that is frequently used to

30 into piperonylic acid (PA), an inhibitor of CINNAMATE-4-HYDROXYLASE (C4H), the enzyme directly upstr

31 id pathway by upregulating the expression of cinnamate-4-hydroxylase (C4H), which catalyzes the secon

32 idopsis under the control of the Arabidopsis cinnamate-4-hydroxylase promoter boosted the p-coumaroyl

33 the control of the lignification-associated cinnamate-4-hydroxylase promoter, but not the commonly e

34 contrast, it shares much less homology with cinnamate-4-hydroxylase, a P450 that catalyzes the hydro

35 These P450 enzymes include trans-cinnamate-4-hydroxylase, p-coumarate-3'-hydroxylase, and

36 ilar to that obtained using alpha-cyano-4-OH-cinnamate, a well established MCT inhibitor.

37 Non-pigmented cinnamates acted as oxidase substrates and induced co-ox

38 a-damascenone, 1-octen-3-ol, acetates, ethyl cinnamate and 4-vinylguaiacol than SGW.

39 ein-10-trans-coumarate, monotropein-10-trans-cinnamate and 6alpha-hydroxy-dihydromonotropein-10-trans

40 For the cinnamate and acrylate substrates studied, the catalysts

41 atalyzes the deamination of phenylalanine to cinnamate and ammonia.

42 ol/benzyl benzoate, dibenzyl ether and ethyl cinnamate and by imaging of neuronal activity in larval

43 gene completely inhibited the production of cinnamate and enterocin, whereas complementation of the

44 reas less activated substrates such as ethyl cinnamate and methyl crotonate required heating (>150 de

45 rresponding recombinant proteins showed that cinnamate and p-coumarate are their best substrates for

46 ta-aryl-substituted acrylate and acrylamide (cinnamates and cinnamides), which are extremely sluggish

47 th three substrates: benzyl chloride, methyl cinnamate, and anthracene.

48 ls-Alder cycloaddition of cyclopentadiene to cinnamates arises from stacking interactions that favor

49 lipase B from Candida Antarctica, and vinyl cinnamate as acyl donor at ratio 250:1 (acyl donor to an

50 el use of ethyl-3-phenylprop-2-enoate (ethyl cinnamate) as a nontoxic solvent-based clearing reagent

51 pon irradiation with 366 nm light, the trans-cinnamate attached to the active-site serine isomerizes

52 es (HPQMs) and curcumins, yielding cinnamoyl cinnamates bearing a diarylalkyl moiety in excellent yie

53 Using ethyl cinnamate-cleared kidneys, we also quantified the averag

54 en lost in selfing C. rubella by mutation of cinnamate-CoA ligase CNL1.

55 nzyme A (CoA) ligase motifs, a cDNA encoding cinnamate:CoA ligase (CNL) was isolated.

56 ents a bona fide 4CL, whereas the other is a cinnamate:CoA ligase (Ph-CNL).

57 ecent identification of the rice peroxisomal cinnamate:CoA ligases (CNLs), we identified 2 peroxisoma

58 submergence-induced peroxisomal Oryza sativa cinnamate:CoA ligases (OsCNLs) are required for this SA

59 We found that the gene encoding a specific cinnamate coenzyme A ligase likely obtained its new func

60 In solution, these cinnamate compounds undergo light-induced (374 nm) E-Z i

61 phine oxide, a range of substrates including cinnamates, crotonates, coumarins, sulfones, and chalcon

62 sidue samples were dominated by benzoate and cinnamate derivatives and triterpenes consistent with a

63 Here we show that macrocyclic cinnamate dimers combine these productive stress-respons

64 cycloadditions between 3-hydroxyflavones and cinnamate dipolarophiles to access (-)-rocaglamide and r

65 sed non-toxic clearing (BALANCE) using ethyl cinnamate (ECi) with light sheet fluorescence microscopy

66 bonyl carbon of ortho-formyl (or ortho-acyl) cinnamate ester followed by intramolecular cyclization a

67 ction parameters via triggering the inactive cinnamate ester moiety.

68 enotoxicity; an alarming concern for current cinnamate ester-based human sunscreens.

69 sily accessible ortho-formyl (or ortho-acyl) cinnamate esters and indoles.

70 -6(7H)-ones from simple 2-formyl (or 2-acyl) cinnamate esters and phenols.

71 , preclinical and clinical trials of topical cinnamate esters as proteasome inhibitors are warranted

72 bitory activity against proteasomes, whereas cinnamate esters displayed the activity.

73 alpha,beta-Unsaturated cinnamate esters irreversibly inhibited the 3CP and disp

74 act was fractionated and found to have novel cinnamate esters that inhibit proteasome activity.

75 tic asymmetric Diels-Alder (DA) reactions of cinnamate esters with cyclopentadiene.

76 imethylchromene and 88-98% ee for a range of cinnamate esters.

77 introduction of p-(meso-triphenylporphyrin)-cinnamate group (TPPcinnamate) on sterically hindered 10

78 Here, we show that the substitution of a cinnamate group for a pair of complementary bases provid

79 when the organic ligands did not contain the cinnamate group.

80 adiation at visible wavelengths at which the cinnamate has no absorption.

81 Thus, a cinnamate inhibitor with a biotin moiety, 1d, was synthe

82 demonstrating that the NH(2)-MIO adduct and cinnamate intermediate are sufficiently retained to cata

83 ipally rebinds to the carbon skeleton of the cinnamate intermediate to complete the alpha-beta isomer

84 which is impaired in the conversion of trans-cinnamate into para-coumarate, displayed similar defects

85 y replace native ligands with functionalized cinnamate ligands, allowing for well-defined, highly tun

86 sed on the combination of thymol (T), methyl cinnamate (M), and linalool (L) has been prepared using

87 Cinnamic acid (CA) and methyl cinnamate (MC) have attracted interest of researchers be

88 thylation, thus designating these enzymes as cinnamate/p-coumarate carboxyl methyltransferases (CCMTs

89 It involves cinnamate radical anions on the CdSe surface, formed upo

90 ted with l-[1-(3)H]arabinose or (E)-[U-(14)C]cinnamate (radiolabelling the pentosyl and feruloyl grou

91 Ethyl cinnamate rapidly cleared all tested organs, including c

92 on aerobic photolysis at 374 nm, the surface cinnamates released coumarin accompanied by rapid nanocr

93 se derivatives, 5c, has photo-cross-linkable cinnamate residues, and we have demonstrated the fabrica

94 vity and selectivity against 2-C-substituted cinnamate salts, whereas rhodium complexes of (S,S)-Ph-Q

95 vity and selectivity against 2-C-substituted cinnamate salts.

96 at reductases with specificities for related cinnamate substrates independently emerged at least four

97 ts of flow on the dimerization of a range of cinnamate substrates.

98 A number of thiols carrying a substituted cinnamate tail was synthesized.

99 nation of Phe to the non-toxic product trans-cinnamate (TCA).

100 anones/chalcones glycosides in safflower and cinnamates/terpenes in calendula.

101 The cinnamate-thiols were successfully exchanged onto the Cd

102 from the excited nanocrystal to the surface cinnamate, undergoing E-Z isomerization.

103 tion of nitrones with different styrenes and cinnamates using a catalytic amount of gamma-cyclodextri

104 d 6alpha-hydroxy-dihydromonotropein-10-trans-cinnamate were isolated.

105 l 2-phenylacetate, cinnamaldehyde and methyl cinnamate were produced during the cultivation period of

106 noids, volatile phenols, vanillins and ethyl cinnamates) were detected in the hydrolysates of 55 frac

107 Reactions of benzyl bromide or benzyl cinnamate with N-(benzotriazol-1-ylmethyl)arylimidoyl ch

108 mination of 3-aryl 2,3-dibromopropanoates to cinnamates with good yield.