ライフサイエンスコーパス: cinnamoyl

1 N-cinnamoyl-1-naphthylamines undergo a cyclization reactio

2 mma-quinide, and 1,3,4-O-tris[3,4-(dimethoxy)cinnamoyl]-1,5-gamma-quinide), finding dissociation cons

3 feoyl-1,5-gamma-quinide, 3-O-[3,4-(dimethoxy)cinnamoyl]-1,5-gamma-quinide, 3,4-O-bis[3,4-(dimethoxy)c

4 -1,5-gamma-quinide, 3,4-O-bis[3,4-(dimethoxy)cinnamoyl]-1,5-gamma-quinide, and 1,3,4-O-tris[3,4-(dime

5 el, semisynthetic triterpenoid derivative, 3-cinnamoyl-11-keto-beta-boswellic acid (C-KbetaBA).

6 Compounds 1-(4-hydroxy-3-methoxy) cinnamoyl-2-acyl-sn-glycero-3-phosphocholine and 1-(4-hy

7 atives, compound 1-(4-hydroxy-3,5-dimethoxy) cinnamoyl-2-acyl-sn-glycero-3-phosphocholine exhibited e

8 osphocholine and 1-(4-hydroxy-3,5-dimethoxy) cinnamoyl-2-palmitoyl-sn-glycero-3-phosphocholine exhibi

9 Compound 1-(4-hydroxy-3-methoxy) cinnamoyl-2-palmitoyl-sn-glycero-3-phosphocholine exhibi

10 ]-l-aspartic acid and N-[3',4'-dihydroxy-(E)-cinnamoyl]-3-hydroxy-l-tyrosine (clovamide).

11 ests that the extinction coefficient for the cinnamoyl acyl-enzyme is larger than previously measured

12 and mild cross-dehydrogenative coupling of 2-cinnamoyl benzaldehydes allowing for the synthesis of 2-

13 Phenolic compounds 1-O-trans-cinnamoyl-beta-d-glucopyranose (2), ellagic acid (3), my

14 Amide formation with cinnamoyl chloride and template 21 followed by photochem

15 rization of polarized alkenes, employing the cinnamoyl chromophore as a retinal surrogate under UV-ir

16 one methides (HPQMs) and curcumins, yielding cinnamoyl cinnamates bearing a diarylalkyl moiety in exc

17 BZO1 is to synthesize the benzoate precursor cinnamoyl CoA rather than to generate benzoyl CoA from b

18 (HSQC) NMR spectra of lignins isolated from cinnamoyl CoA reductase (CCR)-deficient poplar.

19 Studies of lignin structure in dwarfed cinnamoyl CoA reductase (CCR)-downregulated tobacco were

20 oyl transferase (HCT) or loss of function of cinnamoyl CoA reductase 1 (CCR1) express a suite of path

21 xpression of the lignin monomer biosynthetic cinnamoyl CoA reductase and cinnamyl alcohol dehydrogena

22 Cinnamoyl CoA reductases (CCR) convert hydroxycinnamoyl

23 ication in intact plants, a microRNA against cinnamoyl CoA-reductase1 driven by the promoter from cel

24 BA beta-oxidative pathway (cinnamic acid --> cinnamoyl-CoA --> 3-hydroxy-3-phenylpropanoyl-CoA --> 3-

25 sgenic lines accumulated the PhCHD substrate cinnamoyl-CoA and the upstream pathway intermediate cinn

26 4-OH-Cinnamoyl-CoA binds tightly (K(d) = 47 nM, pH 6) to the

27 e crystal structure of (N,N-dimethyl-p-amino)cinnamoyl-CoA bound at the enzyme active site, the shiel

28 benzenoid network and provide evidence that cinnamoyl-CoA formation by Ph-CNL in the peroxisomes is

29 first step in the beta-oxidative pathway is cinnamoyl-CoA formation, likely catalyzed by a member of

30 4-OH-Cinnamoyl-CoA has been synthesized as a probe of the act

31 oA, cinnamoyl-CoA, and (N,N-dimethyl-p-amino)cinnamoyl-CoA have been experimentally determined.

32 , we have identified a petunia gene encoding cinnamoyl-CoA hydratase-dehydrogenase (PhCHD), a bifunct

33 The enzymes cinnamoyl-CoA reductase (CCR) and cinnamyl alcohol dehyd

34 the cinnamyl alcohol dehydrogenase (CAD) and cinnamoyl-CoA reductase (CCR) families in wood formation

35 dicated that the irx4 mutation occurred in a cinnamoyl-CoA reductase (CCR) gene within a highly conse

36 Suppression of the lignin-related gene cinnamoyl-CoA reductase (CCR) in the Pinus radiata trach

37 Cinnamoyl-CoA reductase (CCR), an enzyme central to the

38 s tremula x Populus alba) down-regulated for cinnamoyl-CoA reductase (CCR), the enzyme catalyzing the

39 lcohol dehydrogenase (CAD; EC 1.1.1.195) and cinnamoyl-CoA reductase (CCR; EC 1.2.1.44) activities in

40 suppression of the petunia (Petunia hybrida) cinnamoyl-CoA reductase 1 (PhCCR1), which catalyzes the

41 cinnamyl dehydrogenase c and d (cadc cadd), cinnamoyl-CoA reductase 1, and reduced epidermal fluores

42 e, chalcone isomerase, isoflavone reductase, cinnamoyl-CoA reductase and caffeic acid O-methyltransfe

43 oA ligase, caffeoyl-CoA O-methyltransferase, cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogena

44 to ) with a region on chromosome 9 harboring cinnamoyl-CoA reductase, a key enzyme in monolignol synt

45 oA ligase, caffeoyl-CoA O-methyltransferase, cinnamoyl-CoA reductase, and cinnamyl alcohol dehydrogen

46 affeoyl-CoA O-methyltransferase1 [CCoAOMT1], cinnamoyl-CoA reductase1 [CCR1], ferulate 5-hydroxylase

47 lytic mechanism and substrate specificity of cinnamoyl-CoA reductases from sorghum (Sorghum bicolor),

48 rate specificity for feruloyl-CoA over other cinnamoyl-CoA thioesters, and the T154Y mutation in SbCC

49 PhCHD revealed it most efficiently converts cinnamoyl-CoA to 3-oxo-3-phenylpropanoyl-CoA, thus formi

50 ith the bound substrate 4-(N,N-dimethylamino)cinnamoyl-CoA using X-ray diffraction data to a resoluti

51 -carbons of the substrates, hexadienoyl-CoA, cinnamoyl-CoA, and (N,N-dimethyl-p-amino)cinnamoyl-CoA h

52 ses the conversion of trans-cinnamic acid to cinnamoyl-CoA, which is subsequently transformed to benz

53 al tropane alkaloids of E. coca, cocaine and cinnamoyl cocaine, were present in highest concentration

54 The cinnamoyl-coenzyme A (CoA) ligase OSD1 catalyses the con

55 Purified enzymes were used to synthesize cinnamoyl-coenzyme A (CoA), p-coumaroyl-CoA, feruloyl-Co

56 Cinnamoyl-coenzyme A reductase (CCR) catalyzes the reduc

57 late 5-hydroxylase) and ccr1g (deficient for cinnamoyl-coenzyme A reductase) lines, albeit to a lower

58 Here, we reintroduced CINNAMOYL-COENZYME A REDUCTASE1 (CCR1) expression specif

59 nnamoylcocaine via the activated benzoyl- or cinnamoyl-Coenzyme A thioesters, respectively.

60 philic block copolymers were prepared from a cinnamoyl-containing hydrophobic norbornene monomer and

61 ptor (MOR) antagonism, but the unsubstituted cinnamoyl derivative (6a) had partial MOR agonist activi

62 We have previously shown that cinnamoyl derivatives of 14beta-amino-17-cyclopropylmeth

63 Eighteen cinnamoyl derivatives, 17 flavonoid derivatives and 4 be

64 lic acid esterase B, FAEB) was shown to be a cinnamoyl esterase (CE), efficiently releasing hydroxyci

65 A cinnamoyl esterase, ferulic acid esterase A, from Asperg

66 on these substrates, but it is not known if cinnamoyl esterases can break these cross-links by cleav

67 14-O-Cinnamoyl esters of naltrexone (6) were synthesized and

68 The FPR-specific peptide, cinnamoyl-F-(D)L-F-(D)L-FK (cFLFLF), was sequentially co

69 to afford the E-isomer sulfonyl analogues of cinnamoyl fluoride in 43-97 % yield.

70 Moreover, two new C-3-cinnamoyl-Glcp analogues (2 and 3) were prepared.

71 st variation between cultivars was found for cinnamoyl glucose (0.6-24.9mg/100g of fw).

72 ding to their abundance in the solution, but cinnamoyl-glucoside anthocyanin forms showed a higher af

73 -rhamnosides, flavonol-3-O-(dihydrophaseoyl, cinnamoyl)glycoside-7-O-rhamnosides and flavonol-3-O-(ma

74 other flavonol-glycosides, and flavonol-3-O-(cinnamoyl)glycoside-7-O-rhamnosides, flavonol-3-O-(dihyd

75 ied as highly abundant 6'-O-(3,4-dimethoxy-E-cinnamoyl)-gomphrenin and 6'-O-(3,4,5-trimethoxy-E-cinna

76 oyl)-gomphrenin and 6'-O-(3,4,5-trimethoxy-E-cinnamoyl)-gomphrenin as well as their isoforms.

77 of the 14beta-cinnamoyl series and that the cinnamoyl group itself may in fact be the dominant bindi

78 es of ligands has been synthesized where the cinnamoyl group of the 14-cinnamoylamino morphinones has

79 cyclic depsipeptide with an unusual 2-methyl-cinnamoyl group.

80 cores by light-activated dimerization of the cinnamoyl groups yielded stable nanoparticles.

81 l motif were preferred over those with trans cinnamoyl groups.

82 Here, we show that this signal is cinnamoyl-HSL and that cinnamoyl-HSL is produced by the

83 rain responds to picomolar concentrations of cinnamoyl-HSL and thus, produces cinnamoyl-HSL in excess

84 trations of cinnamoyl-HSL and thus, produces cinnamoyl-HSL in excess of the levels required for a sig

85 w that this signal is cinnamoyl-HSL and that cinnamoyl-HSL is produced by the LuxI homolog BraI and d

86 Cinnamoyl-HSL reaches concentrations on the order of 50

87 of Bradyrhizobium to produce and respond to cinnamoyl-HSL shows that aryl-HSL production is not uniq

88 duction of the aryl-HSLs p-coumaroyl-HSL and cinnamoyl-HSL, respectively.

89 integrated to propose a binding mode for the cinnamoyl inhibitors at the active site of HIV-1 IN.

90 series of potent conformationally restrained cinnamoyl inhibitors of HIV-1 IN.

91 nt metabolite, followed by N-[4'-hydroxy-(E)-cinnamoyl]-l-aspartic acid and N-[3',4'-dihydroxy-(E)-ci

92 N-[3',4'-dihydroxy-(E)-cinnamoyl]-l-aspartic acid was the most abundant metabol

93 To investigate the importance of the cinnamoyl ring substituent, a series of analogues have b

94 ay a major role in the binding of the 14beta-cinnamoyl series and that the cinnamoyl group itself may

95 The diblock copolymer consisted of a cinnamoyl-substituted polymethacrylate block for attachm

96 The cinnamoyl-subtilisin structures are virtually identical

97 The x-ray crystal structures of trans-cinnamoyl-subtilisin, an acyl-enzyme covalent intermedia

98 aximum at 498 nm resembling the natural 4-OH-cinnamoyl-thioester chromophore of the photoactive yello

99 ed cascade conjugate addition-intramolecular cinnamoyl transfer ("cut and sew") strategy involving 2-

100 Furthermore, the cinnamoyl transfer products are amenable for a variety o

101 parallel arrangement of covalently attached cinnamoyl units suitable for stereoselective photodimeri