ライフサイエンスコーパス: circuit

1 to subsequently be detected via the resonant circuit.

2 because the His bundle is obligatory to the circuit.

3 complexity equivalent of a reference quantum circuit.

4 lopment and integration into the hippocampal circuit.

5 phase bias to the wave function of a quantum circuit.

6 re and activity in the same frontal cortical circuit.

7 n feedforward functional connectivity in the circuit.

8 for the eS6 phosphorylation (eS6-P) control circuit.

9 ng in distinct neural sites of the olfactory circuit.

10 he negative feedback loop of its own genetic circuit.

11 unctional synaptic specification in a neural circuit.

12 d to create highly nonlinear single-molecule circuits.

13 a strong innate component embedded in reward circuits.

14 representational warping in decision-making circuits.

15 ed neuronal activity in spinal sensory-motor circuits.

16 ight separate hygrosensory inputs from motor circuits.

17 ate the organization of hypothalamic feeding circuits.

18 ough a parallel set of resistors in electric circuits.

19 l patterning to the assembly of limb control circuits.

20 y thin superlattices, devices and integrated circuits.

21 on a combination of feedback and feedforward circuits.

22 and to understand the function of biological circuits.

23 ode in both male aggression and reproduction circuits.

24 tivity within cortico-basal-ganglia-thalamic circuits.

25 sensor-actuator pairs controlled by digital circuits.

26 ence within neocortical-medial temporal lobe circuits.

27 BLADE platform across the range of possible circuits.

28 is a powerful tool for the study of neuronal circuits.

29 m algorithm is represented by set of quantum circuits.

30 logical function(s) and regulatory signaling circuits.

31 sitional-autonomic, orienting, and vigilance circuits.

32 chanical resonators, and integrated photonic circuits.

33 structure, function, and pathology of neural circuits.

34 the reward circuitry and interacting stress circuits.

35 resources, whereas others rely on separable circuits.

36 lone, but also depend on developing premotor circuits.

37 stent voltage bias that can power electronic circuits.

38 th cognitive, affective, and motor forebrain circuits.

39 ne-engineering with synthetic co-stimulatory circuits.

40 proach identifies homologous neurobiological circuits across individuals.

41 We examined dopamine circuit activity at various stages, including somatic sp

42 Within mammalian brain circuits, activity-dependent synaptic adaptations, such

43 ell gene expression profiling and anatomical circuit analyses of vermis output neurons in the mouse f

44 rade trans-synaptic viral vectors for neural circuit analysis in multiple species.

45 H129) are important tools for mapping neural circuit anatomic and functional connections.

46 articipate in decision-making but the neural circuit and molecular bases for these functions are litt

47 surements to fully parameterize a regulatory circuit and quantify its impact on host.

48 These results illustrate a circuit and synaptic basis of aggression modulation by e

49 imulatory effects of nicotine on the mHb-IPn circuit and thereby regulate nicotine avoidance behavior

50 bute to developmental refinement of neuronal circuits and associated behaviors.

51 juvenile critical period consolidates neural circuits and behavior, but this limits functional recove

52 ach somatostatin to specific nervous systems circuits and behaviors in this important jawed vertebrat

53 rved, canonical properties of the functional circuits and computational algorithms for motion vision.

54 hese efforts have provided insights into the circuits and intracellular pathways in the brain reward

55 reside alongside the cardiovascular control circuits and mediate increases in blood pressure and hea

56 asks to assess functional integrity of brain circuits and multiple cognitive domains in a non-aversiv

57 gap in quantitatively describing hippocampal circuits and provides useful model specifications for bi

58 how the neuropeptide oxytocin impacts these circuits and their downstream effects on social behavior

59 aling have been observed only within central circuits, and on the postsynaptic side.

60 Under constant light conditions, the gravity circuit appears to be inoperable, and both upward and do

61 Characterising the circuit architecture of these diseases could illuminate

62 mechanisms, embedded in a dynamic, recurrent circuit architecture.

63 e neural activity across this brainstem-wide circuit are lacking.

64 While neurons and circuits are almost unequivocally considered to be the c

65 Finally, various functional logic gates and circuits are demonstrated.

66 ions of transsynaptic AAV1 in probing neural circuits are described.

67 underlying functional properties of cortical circuits are poorly understood.

68 Integrated circuits are present in all electronic devices, and enab

69 ensory comparisons and the underlying neural circuits are still largely unknown.

70 onnectivity and whether its local excitatory circuits are sufficient to generate epileptiform activit

71 logy, genetic elements, combined into simple circuits, are used to control individual cellular functi

72 he molecular mechanisms regulating DG neural circuit assembly and function remain unclear.

73 dscaml1) are essential regulators of neural circuit assembly, but their roles in vertebrate neural c

74 or treating hyperexcitability of hippocampal circuits associated with neuroinflammation in epilepsy a

75 Here we identify an adaptive circuit-based mechanism that enables Drosophila to form

76 The circuit behaves as designed; however, it is riddled with

77 her complexity of dopaminergic reinforcement circuits between and within MB compartments.

78 Executing gene circuits by cell-free transcription-translation into cel

79 positive over neutral memories, the VTA->DH circuit can facilitate the selection of adaptive behavio

80 These initial processing circuits can incorporate subcortical regions, such as th

81 This requires activity of both brain circuits capable of processing sensory modality-specific

82 d primer-exchange-reaction-based biochemical circuit cascade, which probes a specific biomolecular in

83 ed with autism spectrum disorders and neural circuit changes in several brain areas, but the cellular

84 esolution have expanded the understanding of circuit changes underlying experience-dependent plastici

85 otein Kinase A (PKA) exist in an oscillatory circuit characterized by a high degree of feedback.

86 second wave of synthetic biology, the simple circuits, combined into complex circuits, form systems-l

87 ovel mechanism for the selection of striatal circuit components, where fluctuating levels of dopamine

88 which, in turn, leads to a change in neural circuit connectivity and disruption of normal behavior.

89 The developed digital circuit consists of inductors sensitive to the transmit

90 The way in which aberrant neural circuits contribute to epilepsy remains unclear.

91 it remains unclear how and whether cellular circuits control the distribution of a complexoform.

92 outline a role for hnRNPs in gene regulatory circuits controlling sterol homeostasis.

93 dus external segment (GPe), and this CeA-GPe circuit conveys unconditioned stimulus (US)-related info

94 duced in the adult: adolescent stress led to circuit deficits that recapitulates schizophrenia, where

95 tions including the potential for connecting circuit-defined subtypes to more distal features derived

96 We propose that the ventral circuit defines behavioral goals, and the dorsal circuit

97 Genetic circuit design automation for eukaryotes simplifies the

98 linically viable iBCIs, and suggest that the circuit design parameters of current recording iBCIs can

99 is reduced to uW-level by a novel integrated circuit design, which considerably extends the maximum o

100 ical settings, such as being introduced into circuit designs for synthetic biology applications.

101 o-temporal code at the output of the antenna circuits determines the level of complexity of olfactory

102 wing a role of autophagy during early neural circuit development and suggests that autophagy in gener

103 standing how spontaneous activity influences circuit development.

104 zation of the brain to later regulate neural circuit development.

105 s of the rate of human VT with comparison of circuit dimensions and conduction velocity (CV) across a

106 are not well suited for applications in CMOS circuits due to difficulties in integrating complementar

107 btypes, mechanisms by which HA modulates NAc circuit dynamics are undefined.

108 heterochromatin dysregulation to cerebellar circuit dysfunction and behavioral abnormalities in ASD.

109 Memristors represent the fourth electrical circuit element complementing resistors, capacitors and

110 elation evident between V(on) and equivalent circuit element parameters commonly associated with HER.

111 be more faithfully emulated by higher-order circuit elements that naturally express neuromorphic non

112 The developmental assembly of this binocular circuit, especially the transcallosal pathway, remains i

113 Here we investigate whether the SubM-VLO circuit exerts descending regulation over airway vagal r

114 Whether separate strongly interacting circuits exhibit traveling waves remains unknown.

115 plasticity of Up-states, however, Fmr1(-/y) circuits exhibited abnormal experience-dependent plastic

116 This circuit exhibits a balance of inhibitory and excitatory

117 al component of the midbrain dopamine reward circuit, exhibits disturbed circadian rhythms in the pos

118 tive agent was then utilized in a custom NMP circuit for the treatment of isolated porcine kidneys, a

119 abetes-related disruptions to three critical circuits for movement control: the cerebral cortex, the

120 , the simple circuits, combined into complex circuits, form systems-level functions.

121 These findings provide a circuit framework through which dopamine neuronal activa

122 In monkeys, a circuit from superior colliculus (SC) through medial-dor

123 Together, our data reveal a neural circuit from VMH to PVT that inhibits food intake.

124 sembly, but their roles in vertebrate neural circuit function are still mostly unexplored.

125 acemaker neurons exert control over neuronal circuit function by their intrinsic ability to generate

126 spike patterns in different environments, a circuit function called "remapping." We tested remapping

127 Despite their importance for neural circuit function, only a little is known about the postn

128 ations are critically reliant on their local circuit, GABAergic cells.

129 Although topographically arranged BG circuits have been described, the extent to which these

130 edispositional insula-based striatal-frontal circuits, highlighting the circuit's potential as a biom

131 So how do cortical circuits implement nonlinear representations and computa

132 ng cortex, but the transformations that this circuit implements are not known.

133 ical-striatal-thalamic-cortical (CSTC) brain circuits implicated in the selection of movements, impai

134 other addictive substances can remold neural circuits important for memory to reduce this flexibility

135 esponsive device using an engineered genetic circuit in E.coli, which responded to microgravity by ch

136 ters Sirtuin-1-hepatic nuclear factor 4alpha circuit in hepatocytes to downregulate ApoM.

137 resynaptic function in a developing neuronal circuit in its native environment is unclear.

138 ENT This study in rats shows that a specific circuit in the brain [i.e., neurons that project from th

139 y a widely distributed NREM sleep-regulating circuit in the brainstem with a common molecular propert

140 ssory olfactory bulb (AOB), the first neural circuit in the mouse accessory olfactory system, is crit

141 Here, we identify a neuronal circuit in the nematode Caenorhabditis elegans that proc

142 nse of V1 to head movements and identifies a circuit in which SOM cells are key integrators of vestib

143 on circuit mapping to interrogate local LCIC circuits in adult mice of both sexes and found that inpu

144 ans and animals have implicated brain reward circuits in aggression and suggest that, in subsets of a

145 (WFHE) with integrated flexible sensors and circuits in an ultrathin, low-modulus elastomer.

146 contribution of inhibitory and facilitatory circuits in M1.

147 struction of multi-input, multi-output logic circuits in mammalian cells.

148 s of these techniques in profiling cells and circuits in mice.

149 review, I discuss newly discovered neuronal circuits in primates that represent uncertainty about fu

150 Animal behavior is encoded in neuronal circuits in the brain.

151 tic finding and address how C4A shapes brain circuits in vivo, here, we generated a mouse model with

152 ws for sophisticated investigation of neural circuits in vivo, that would otherwise be impossible in

153 Modulation of this circuit induced social deficits and repetitive behaviors

154 We suggest that this darcin-activated neural circuit integrates pheromonal information with internal

155 gs demonstrate how excitatory and inhibitory circuits interact to mediate an ethologically relevant n

156 ions(1) converts macroscopic superconducting circuits into artificial atoms(2), enabling some of the

157 sentations of chemical reaction networks and circuits into hardware configurations that can be used t

158 term effects of manipulating the activity of circuits involved in opioid-mediated physiology and beha

159 Dysfunction of neuronal circuits is an important determinant of neurodegenerativ

160 ation and inhibition (E-I balance) in neural circuits is believed to be tightly regulated.

161 ate of electron flux through redox buffering circuits is directly linked to changes in oxygen consump

162 Plasticity within hippocampal circuits is essential for memory functions.

163 We propose that the complexity of cortical circuits is generated by phylogenetically old interneuro

164 ling the organization and function of neural circuits is greatly facilitated by viral tools that spre

165 exibility is achieved at the level of neural circuits is not understood.

166 properties, but their relationship to brain circuits is unclear.

167 To understand the function of cortical circuits, it is necessary to catalog their cellular dive

168 Our results lay the foundations for a circuit-level analysis of economic decisions.

169 Nevertheless, the circuit-level consequences of such reactivations remain

170 scales by linking cellular nonlinearities to circuit-level decision-making, establishes that distribu

171 robust and accurate time-keeping arises from circuit-level interactions that bind its individual cell

172 The compiler also creates circuit-level models of the target configuration, which

173 Mechanisms of cellular and circuit-level plasticity continue to shape and reshape m

174 nput streams, we used laser photostimulation circuit mapping to interrogate local LCIC circuits in ad

175 k of local connectivity, we used optogenetic circuit mapping to study the strength of LH optogenetic

176 viruses that have been developed for neural circuit mapping, and we provide a primer on currently ap

177 These circuit maps were reproducible, predicted symptom improv

178 ous nodes of this PFC-BNST dynorphin-related circuit may serve as potential targets for potential the

179 e, we set out to examine how song-generating circuits may be influenced early in song learning by a c

180 These mono- and polysynaptic circuits may underlie polarized motor reflexes evoked by

181 f SST interneurons and a putative downstream circuit mechanism as an effective method for enhancing e

182 s suggests autoreception may be an important circuit mechanism by which octopamine modulates behavior

183 r, our results thus characterized a synaptic circuit mechanism that may underlie the prevalent essent

184 Our findings thus unravel a circuit mechanism that underlies accurate detection of h

185 irment and wandering behavior, but the brain circuit mechanisms causing such symptoms remain largely

186 and cognitive processes, but the underlying circuit mechanisms remain poorly understood.

187 However, the neural circuit mechanisms underlying this ability are unclear.

188 at major depressive disorder, yet the neural circuit mechanisms underlying this therapeutic effect re

189 ressive diversity of molecular, cellular and circuit mechanisms, embedded in a dynamic, recurrent cir

190 tner choice and therefore ultimately control circuit membership.

191 ent depends on activity resulting from their circuit milieu.

192 Using a neural circuit model of decision uncertainty and change-of-mind

193 presynaptic partners and with comprehensive circuit modeling.

194 ar cortical function based on the pioneering circuit models described by John Eccles, Masao Ito and J

195 Examining a large family of circuit models with non-identical neurons and synapses u

196 synaptic connections reveals three recurrent circuit modules engaged sequentially to increase locomot

197 on networks, consisting of multiple forms of circuit motifs including reciprocal (inhibitory interneu

198 Striatal circuits must be modulated for behavioral flexibility, t

199 r input from bipolar cells, excitatory local circuit neurons receiving input from cones.

200 ing peptide produced only by circadian clock circuit neurons.

201 rectal cancer), integrated in the electrical circuit of a direct methanol fuel cell (DMFC), working i

202 td15a and kctd15b transcription, unveiling a circuit of autoregulation operating in nephron progenito

203 = 212), we characterized how a heterogeneous circuit of swine shows, comprising fairs with different

204 uild increasingly large and complex photonic circuits on the surface of a chip.

205 uit defines behavioral goals, and the dorsal circuit orchestrates behavior to achieve those goals.

206 tion, behavior, and mind based on underlying circuit organization.

207 been done to test the role of specific clock circuit output signals.

208 Imaging neurons and neural circuits over large volumes at high speed and subcellula

209 range of scales, from individual synapses to circuit pathways.

210 on patterns can have a significant effect on circuit performance and illustrate the need for a compar

211 d, aimed at using natural enzymes to improve circuit performance, although, at the cost of increased

212 an distinguish laminar specificity of visual circuit plasticity in humans.

213 We demonstrate the application of open circuit potentiometry (OCP) to measure enzyme turnover k

214 ing is achieved by dismantling the binocular circuit present at critical period onset and building it

215 add sender devices, the resulting patterning circuit produces theoretically predicted self-organised

216 of reward-related phenotypes and is a novel circuit promoting consumption of ethanol and palatable f

217 spatially covary in molecular, cellular, and circuit properties.

218 w a dedicated laryngeal sensory motor reflex circuit protects our airways from aspirated foods or liq

219 CR expression and function in the egg-laying circuit provides a model for understanding GPCR signalin

220 e observed in lesion studies of the grasping circuit, providing a potential model for how brain regio

221 lly, performing inference on the activity of circuits pushed far out of equilibrium by a simple low-d

222 Here, we used the nuclear Auxin Response Circuit recapitulated in yeast (Saccharomyces cerevisiae

223 y that is critical for proper maturation and circuit refinement.

224 d, alleviating a major safety concern (short-circuiting related to Li dendrite growth).

225 at the identified trans-species ACC-striatal circuit relationship with nicotine dependence severity i

226 ential for survival, the underlying neuronal circuits remain undefined.

227 n this context, the resulting neuron-synapse circuits require multiple transistors and complicated la

228 disrupts a core pluripotency transcriptional circuit required for Epha2 gene expression.

229 oes possess the central or peripheral neural circuits required to host-seek and that removing fruitle

230 Precise analysis of complex neural circuits requires high-density integration of multiple c

231 nderlying rhythmic behavior, we analyzed the circuits' response to modifications in single and multip

232 striatal-frontal circuits, highlighting the circuit's potential as a biomarker of dependence severit

233 disrupting this process on sensory and motor circuits.SIGNIFICANCE STATEMENT Disrupted mitochondrial

234 understanding GPCR signaling in other neural circuits.SIGNIFICANCE STATEMENT Neurotransmitters signal

235 dulating working memory coding in prefrontal circuits.SIGNIFICANCE STATEMENT Ongoing delay activity o

236 t currently limits its use to unidirectional circuits.SIGNIFICANCE STATEMENT The discovery of anterog

237 on sensitive periods and their regional and circuit specificity and highlight the challenge and powe

238 ects without necessarily restoring wild-type circuit states, while highlighting the potential of inte

239 e, we report a flexible microwave integrated circuit strategy integrating membrane AlGaN/GaN high ele

240 ms by which activity and experience modulate circuit structure and function.

241 (2)O by electrons drawn from redox buffering circuits supplied by NADPH, and that the rate of electro

242 from different laboratories and identifies a circuit that can be used in future studies of upstream a

243 se a competitor drug into the extracorporeal circuit that increases the free fraction of a toxic drug

244 l identity and the promotion of a regulatory circuit that is beneficial for tumor initiation and prog

245 ir dependence on SC activity could reflect a circuit that prioritizes cortical processing of events d

246 mechanism generates a metabolic homeostatic circuit that protects cells from bioenergetic crisis and

247 at they are embedded in a cold "thermometer" circuit that provides powerful and persistent inhibition

248 hese findings reveal an AURKB-MYC regulatory circuit that underlies T cell leukemogenesis, and provid

249 The brains of young songbirds develop motor circuits that achieve the goal of imitating a specific t

250 realizing large-scale LN photonic integrated circuits that are of immense importance for broad applic

251 ork lays the foundation for adaptive genetic circuits that can be tuned after their physical assembly

252 Neuronal circuits that control motor behaviors orchestrate multip

253 y capacity of 3D cultures to form functional circuits that could be used to understand development an

254 x, the functional neuroanatomy of the neural circuits that generate expiration is debated.

255 ween model outputs and data on the other 111 circuits that have so far been experimentally constructe

256 Model simulations of the remaining 143 circuits that have yet to be tested experimentally predi

257 a reduced spiking model of sensory cortical circuits that incorporated the signature short-term syna

258 However, little is known about the circuits that integrate these time cues to drive a coher

259 teral inhibition is a fundamental feature of circuits that process sensory information.

260 ules and anterior prefrontal cortex, forming circuits that seem to be unique for non-human primates a

261 se changes serve to improve the functions of circuits that underlie decision-making.

262 The ventral circuit, that includes the amygdala, ventral medial pref

263 Incorporated with a wireless circuit, the sensor platform achieves continuous sensing

264 te its coactivator function in the NF-kappaB circuit thereby promoting insult resolution.

265 e the battery cell as a resonator in a tuned circuit, thereby allowing signals to be excited inside t

266 a crucial regulator of VEGFR-Notch signaling circuit through HIF-1alpha and RBPJkappa in EC sprouting

267 multiple arousal-promoting and motor-control circuits through extensive collateral projections.

268 nnectivity and function in the sensory-motor circuit to improve the SMA motor phenotype.SIGNIFICANCE

269 which high levels of plasticity allow neural circuits to be tuned for optimal performance.

270 n within the PVH that impinges upon multiple circuits to govern appetite.

271 he physiological output of intestinal neural circuits to maintain gut homeostasis and health.

272 mised the in vivo ability of visual cortical circuits to recover from perturbations to sensory drive.

273 (i) the characterization of different brain circuits to understand their normal function as well as

274 We perform circuit tracing in the D. sechellia brain, and find that

275 and suggest that dopamine modulates how this circuit tracks accumulating uncertainty during decision-

276 practical and technical challenges with RLC circuits, transcending existing theoretical construction

277 g of their myelination profiles to diversify circuit tuning in response to sensory experience.

278 uence the function of NAc and related reward circuits, ultimately leading to addictive behaviors.

279 tism spectrum disorders (ASDs); however, the circuits underlying cerebellar contributions to ASD-rele

280 Although the neural circuits underlying more direct forms of learning have b

281 A circuit understanding of how perception links to respons

282 The relation between open-circuit voltage, dark current, and noise current is demo

283 vice performance by mainly limiting the open circuit voltage, interfacial layers are also crucial.

284 FC dose calculation included weight, bypass circuit volume, hematocrit, and intraoperative measured

285 This circuit was found to be stable under laboratory conditio

286 astructural analysis to the retinogeniculate circuit, we find that visual experience alters the numbe

287 ting the model on experimental data from two circuits, we demonstrate close agreement between model o

288 To resolve the precise connectivity of these circuits, we first mapped mouse visual cortical areas us

289 ly designed nanometric holes in the photonic circuit, which are available for analyte detection with

290 The formation of corticospinal (CS) circuits, which are essential for voluntary movements, i

291 n be used to both analyze and design genetic circuits while accounting for spatial intracellular effe

292 nput into a structurally accessible form for circuit wiring, translate the input information into an

293 s of eS6-P can be explained by a feedforward circuit with inputs from both circadian and diel cycles.

294 ecularly-specific, focal modulation of brain circuits with low off-target effects can lead to breakth

295 opic quantum dynamics in ultrahigh-impedance circuits, with potential applications in quantum computi

296 ese are but one of many types of neuroimmune circuits, with the vagus nerve and sympathetic innervati

297 FICANCE STATEMENT A corollary discharge (CD) circuit within the brain keeps an internal record of phy

298 isms by which LLTS affect the central neural circuits within the brain regions that are important for

299 est context-specific regulation of tuft-ILC2 circuits within the small intestine.

300 Ideas about how this circuit works are based largely on models those consider