ライフサイエンスコーパス: classic

1 our rotaxanes and catenanes is based on the classic 1,10-phenanthroline-copper(i) metal template str

2 rwin's writings directly influenced Mendel's classic 1866 paper, and his letters to Nageli.

3 for their proper morphogenesis, evoking the classic A-C antagonism of the ABC model for floral organ

4 y expressed among the control, mild A-T, and classic A-T groups.

5 hylation profiling in patients with mild and classic A-T progression as well as healthy controls.

6 Classic alignment methods such as in the popular XCMS pa

7 ere, we go beyond competitive inhibitors and classic amphetamines and introduce concepts for partial

8 ontinued exploration and development of both classic and alternative methods of detecting biothreat a

9 Classic and contemporary thermal and photochemical radic

10 Direct comparison of classic and high-pressure conditions of the quaternizati

11 A classic and highly influential model of visual processin

12 We identified activation of both classic and new cell signaling pathways that may be targ

13 hogenic variant in B3GLCT who presented with classic anterior segment findings, systemic abnormalitie

14 LC39A9-shRNA or G(alphai)-shRNA, and not the classic antiandrogens including enzalutamide, bicalutami

15 A classic application is to use CRISPR/Cas to generate gen

16 of mice in genetic study, the development of classic approaches to genome modification, and how such

17 bove 20 degrees C, mostly deviating from the classic Arrhenius-type behavior.

18 Second, many classic assumptions about the difference between the two

19 cascade provides a full-loop mechanism for a classic autoregulatory feedback loop proposed ~25 years

20 thogens were detected using, as appropriate, classic bacteriology, immunoassays, gel-based PCR and re

21 This view cannot be properly tested through classic behavioral and neuroimaging approaches due to th

22 to thoughtfully combine these new tools with classic behavioural and ecological monitoring methods to

23 Previous work has identified three classic biases, known as the attraction, similarity, and

24 p is highly structured even beyond the three classic biases.

25 est a clear explanation that is based on the classic biochemical principles of allostery and cooperat

26 le and can be subdivided into three strains: classic BSE and atypical BSEs (H and L types) that have

27 However, the classic BSN model requires near-instantaneous transmissi

28 and 8-10 cm in 96 (32%; subgroup B), whereas classic bulky (diameter > 10 cm) was detected in 99 (33%

29 (95% CI, 77% to 96%; P = .53) in subgroup C (classic bulky).

30 chieving "diversity with ease", by combining classic C-C pai-bond click chemistry with recent develop

31 deficient in complement factor H (CFH) are a classic C3G model, with kidney disease that requires sev

32 A classic case of difficult phase transformations is the n

33 In a classic case of reciprocity, vampire bats share blood wi

34 ly method, which has several advantages over classic case-control tests, in particular by avoiding re

35 ximates the [Formula: see text] precision of classic cataract measurements carried out with the great

36 lus pairs on either side, thus producing the classic "category boundary" effect.

37 We reiterate classic cautions against inferences about competitive hi

38 the exception of CD8(+) alphabeta T and non-classic CD4(+) alphabeta T(H)1(*) lymphocytes, which pro

39 lly no doubts remain that CXCR4 represents a classic chemokine receptor, functions assigned to ACKR3/

40 Since in classic chemotherapies it is observed a decrease in immu

41 However, the classic chronic social defeat stress procedure is limite

42 While our findings with rats are contrary to classic claims of an impervious geometric module, they a

43 grouped into two types: 'bla(TEM-1B) ' and 'classic class 1 integron (IntI1)'.

44 raretinal fluid than eyes with predominantly classic CNV (both P < 0.01).

45 Eyes with predominantly classic CNV (mean best-corrected visual acuity [BCVA], 4

46 t extraction (PE), spanning the range of the classic Coffee Brewing Control Chart.

47 These subfractions of the classic collector efficiency were upscaled to continuum-

48 We demonstrated that unlike the classic comb filter approach, the signal extracted with

49 Classic comparative methods do not account for discordan

50 Our simulations show that the classic competition-colonisation trade-off is highly sen

51 endothelial cells that does not activate the classic complement cascade can trigger the recruitment o

52 er evaluates data imputation results through classic computational criteria and, unprecedentedly, pro

53 iations (creative destruction) is central to classic concepts of macroevolution(1,2).

54 Compared with LSCs prepared with classic CsPbI(3) NCs, the stability of the LSCs after TP

55 particular, it is widely accepted that in a classic cubic-to-tetragonal phase transformation, with o

56 at Tikal during the Late Preclassic to Late Classic cultural periods.

57 gh being generally far better tolerated than classic cytotoxic chemotherapy, this treatment, too, may

58 Classic debates concerning the extent to which scientist

59 xide functionality could be competitive with classic decomposition of alkoxy radicals.

60 ived from a small number of initial studies, classic definitions for concepts of gene regulation have

61 of multiple sclerosis pathology outside the classic demyelinating lesion.

62 teretic current-voltage dependence as well a classic dependence of magnetic flux on electric charge.

63 Lactose metabolism presents both classic diauxic behaviors and long-term memory, where th

64 features resembling PPS maculopathy but not classic disease; and 1091 patients showed evidence of di

65 features resembling PPS maculopathy, but not classic disease; and clearly distinct from PPS maculopat

66 A classic distinction in spatial ecology is between range-

67 In understanding external selection, a classic distinction is made between voluntary (goal-dire

68 inst chewing and sap-feeding herbivores than classic diversity indices.

69 Comparing with classic DNA electrochemistry based mutation detection st

70 The classic doctrine of parameterization is that a parameter

71 ry D(2) receptors that is reminiscent of the classic dopaminergic indirect and direct pathway within

72 Classic dyes, such as thioflavin T and Congo red, exhibi

73 thoidichnites occurs stratigraphically below classic Ediacara body fossils.

74 Instead of focusing on the three classic effects, we sampled decoy stimuli exhaustively a

75 referred to as the "terminal web." Although classic electron microscopy studies revealed complex ult

76 Here we show that the N170, a classic electrophysiological marker of the structural en

77 eficient pancreatic cancer cells up-regulate classic EMT regulator Slug, providing a link between nut

78 The classic endothelial rejection line should be kept in min

79 networks comprised of mass-action kinetics, classic enzyme kinetics (Michaelis-Menten, Briggs-Haldan

80 ting and X-chromosome inactivation (XCI) are classic epigenetic phenomena that involve transcriptiona

81 ciences by application of click chemistry or classic esterification and amidation.

82 We previously observed classic evidence of protein misfolding in mutations with

83 pecify cell fates during development, with a classic example being the bone morphogenetic protein (BM

84 A classic example is contour integration, in which separat

85 A classic example is the ventriloquism aftereffect, which

86 pled chromium(III) metal ions and provides a classic example of a magnetic molecular system that pose

87 The mammal vertebral column is a classic example of a metameric structure that is both mo

88 system parallels, in space and phenotypes, a classic example of coevolution between predatory common

89 ophis) in western North America has become a classic example of coevolution, shedding light on predat

90 [Formula: see text] (LSNO) is a classic example of such a material.

91 A classic example of the latter is gecko feet, where hiera

92 ctive pharmaceutical ingredients (APIs) is a classic example.

93 In addition to the classic exclusion conferred by the phage immunity repres

94 A classic explanation for the prevalence of such warfare i

95 s study of 55 males (mean age 27 years) with classic Fabry disease genotype and/or phenotype, we perf

96 In males with classic Fabry disease, the processes leading to the freq

97 Specifically, we analyzed the classic face-selective N170 component at occipitotempora

98 spects of nucleation that remain elusive for classic, fast earthquakes.

99 factor) that drive beta-cell hyperplasia (a classic feature of obesity).

100 Although some of the classic features of contraction assume a uniform behavio

101 TBK1-associated glaucoma exhibits classic features of NTG.

102 ale proteomics approaches by speeding up the classic filter aided sample preparation protocol, FASP,

103 Classic filtration models assume a homogeneous pore spac

104 work, we find a robust sex difference in the classic forced-choice jealousy task.

105 tigated the genetic basis of plasticity in a classic functional trait, alcohol dehydrogenase (ADH) ac

106 IX activation by 2 independent pathways: the classic FXIIa-FXI-FIX pathway and direct kallikrein acti

107 so accumulate in humans who have the disease classic galactosemia.

108 Thus, Tfh induced in classic GC reactions are dispensable for T1D, but the au

109 Their classic generation from alkyl halides has a severe drawb

110 Most classic genetic approaches utilize binary modifications

111 genes and other targets that were missed by classic genetic approaches.

112 Classic genetic diseases in which HLH is a typical and c

113 The classic genetic explanation is antagonistic pleiotropy:

114 As a complementary approach to these classic genetic methods, we describe a plasmid-based lib

115 t result in exon duplication undetectable by classic genome-wide association studies.

116 s, including antimicrobial resistance (AMR), classic genotyping, and whole-genome sequencing results.

117 Some classic Gestalt principles of contour integration, and m

118 ontrast to the transverse magnetic mode of a classic Goubau line.

119 This reaction utilizes the classic halonium intermediate as a regio- and stereochem

120 , we compare sweep signatures expected under classic hard sweeps with those resulting from adaptive i

121 We first extend the classic hawk-dove model of the evolution of animal aggre

122 ixty-eight patients with purine analog-naive classic HCL were randomly assigned 1:1 to concurrent ver

123 Unlike classic HCN channels, HCNL1 is not gated by cyclic nucle

124 djusted pH-shift process was lower than with classic heat-induced oil isolation (90 degrees C/20 min)

125 classification into one of the four types of classic HL (nodular sclerosis, mixed cellularity, lympho

126 second-line treatments in 127 patients with classic HL who experienced relapse.

127 Classic Hodgkin lymphoma (cHL) is the cancer type most s

128 st-line treatment of early-stage, favorable, classic Hodgkin lymphoma (ES-HL).

129 Previously untreated patients with classic Hodgkin lymphoma were eligible for study enrolme

130 molecularly related B-cell malignant tumor (classic Hodgkin lymphoma), tumor Reed-Sternberg cells ov

131 adopt two distinct amphipathic structures: A classic horizontal helix (horine) and a novel vertical s

132 des a hitherto undescribed function of these classic hormones and suggests that hormonal signaling pl

133 In this context, classic host-guest chemistry, based on the development o

134 Here, we test the classic hypothesis that C(4) grasses evolved stronger me

135 rmation directed by interactions between the classic I44 hydrophobic face of the distal Ub and the co

136 LM flap technique is more effective than the classic ILM peeling for the closure of large stage 4 MHs

137 The classic immune response is the TB granuloma organized in

138 Concurrent classic immunomodulatory therapy (IMT) was given to 251

139 , zygotic and maternal SMCHD1 regulate three classic imprinted clusters and eight other genes, includ

140 t the stage for those advances, or that are "classics" in the area, are also included to provide cont

141 es, FOXA1(+) TNBC tended to be SFK_pY527(+) (classic inactive SFK), and FOXA1(-) TNBC tended to be SF

142 anagement of PCa patients outside the 2 main classic indications (BCR and presurgical staging) across

143 (i.e., a basket trial) excluding the 2 main classic indications: BCR and presurgical staging.

144 rved that is similar in its structure to the classic indirect pathway of the basal ganglia that also

145 s CD8(+) T cell populations specific for two classic inflationary epitopes, M38 and IE3.

146 In addition to IL-10's classic inhibitory effects on myeloid cells, we also des

147 in modulates YAP transcriptional activity in classic insulin target cells, namely HepG2 and C2C12.

148 We study classic interfaces-namely, Schottky junctions-formed by

149 e immune response which typically reacts to "classic invasions" such as bacteria or viruses as well a

150 28 MIS-C, 20 healthy control subjects and 20 classic Kawasaki disease (KD) patients were retrospectiv

151 Unlike classic KD, coronary arteries may be spared in early MIS

152 assification, evaluating this approach and a classic label propagation technique on hundreds of diver

153 Our review is framed by Fodor's classic language of thought hypothesis, according to whi

154 uding increased contacts between the NTD and classic LBD agonist-binding sites.

155 rome, and neurometabolic conditions, such as classic Lesch-Nyhan syndrome.

156 The classic LFP events of the CA1 region, sharp-wave ripples

157 Clinical case review in comparison with classic LFS cohorts demonstrated similar rates of pediat

158 compared to acquisition is a key feature of classic life-history theory, but appears to have been lo

159 Like all classic ligases, NgrRnl forms a covalent lysyl-AMP inter

160 re at odds with hydrolysis mechanisms in the classic literature.

161 Classic LMMs assume independence between random effects,

162 that inhibition by aryl sulfonamides and by classic local anesthetics might show an interaction medi

163 hese studies link a novel incarnation of the classic lysis inhibition phenomenon with conserved defen

164 la leaf marking as a model, we show that the classic M. truncatula leaf anthocyanin spot trait depend

165 Genetic and morphological analysis of the classic maize adherent1 (ad1) mutant was combined with g

166 ors that deviate from the predictions of the classic Marcus theory.

167 Vimentin is a classic marker of epithelial-to-mesenchymal transition a

168 These include classic markers such as p16, senescence-associated beta-

169 s highly volatile dynamics when viewed using classic market measures.

170 ntroduced for nonresponders or patients with classic medulloblastoma (CMB) or large-cell/anaplastic m

171 r in formate dehydrogenase proceed through a classic metal hydride.

172 s of the scaling relationships that exist in classic metal hydrides reveal that hydride donors suffic

173 lecular catalysts have exclusively relied on classic metal hydrides, where the proton and electrons o

174 Here, we utilize long-term data on a classic metapopulation system - the Glanville fritillary

175 C-miR146a reduced expression of classic miR-146a targets (IRAK1 and TRAF6), thereby bloc

176 perresolution imaging of human RPE1 cells, a classic model for studying primary cilia in vitro, with

177 Chymotrypsin inhibitor 2 (CI-2) is a classic model for two-state cooperative protein folding

178 understanding of symbiotic persistence in a classic model of symbiosis.

179 lled challenge, we previously showed that no classic model of vision, including ffCNNs, can explain h

180 sponse to various environmental stimuli in a classic model organism Saccharomyces cerevisiae has not

181 l biology has long benefited from studies of classic model organisms.

182 es a more detailed reaction pathway for this classic model system under considerably simplified react

183 se II is highly conserved among eukaryotes ("classic model").

184 Classic models for the development and evolution of ant

185 While classic models for the emergence of pastoral groups in I

186 howed that these results are consistent with classic models of ITD coding and can explain the ITD tun

187 We found that a whole-arm model, unlike classic models, successfully predicted how features of n

188 ons of the direct pathway unaccounted for in classic models.

189 transcriptomic and epigenomic analyses, and classic molecular biology and biochemical approaches to

190 tal problem that has hindered the use of the classic Monod-Wyman-Changuex (MWC) allosteric model sinc

191 rstand genotype-negative disease eluding the classic monogenic paradigm.

192 et of imaginal disc cells and functions as a classic morphogen to regulate pattern and growth by diff

193 In addition to classic motor symptoms, non-motor manifestations (such a

194 agonists, such as the benzomorphans, and the classic mu opioid antagonists, naloxone, naltrexone, and

195 that androgens may not only function via the classic nAR to increase the nAR-positive BCa cell invasi

196 Using commercially available, classic Noyori Ru(II) -diamine-diphosphine catalysts, we

197 ith normal hair and nails, distinct from the classic nude/SCID phenotype in individuals with autosoma

198 ndle-shaped cells, an insignificant role for classic oncogenes in tumor development, the release of b

199 ctive conformations from those stabilized by classic opioid drugs or G protein-biased agonists, how t

200 re them with analogous data obtained for the classic opioid morphine and the G protein-biased ligand

201 ng on the same opioid receptors triggered by classic opioids-in particular the u-opioid receptor (MOR

202 how different types of foraging frameworks (classic optimal foraging theory, nutritional ecology, he

203 Classic or serotonergic hallucinogens comprise the third

204 er the ultrasonic-based FASP protocol or the classic overnight one.

205 conduction mechanism is identified based on classic oxygen vacancy conductive channels.

206 We report the evolution from classic palladium-catalyzed cross-coupling approaches to

207 lic AMP (cAMP) receptor protein (CAP) is the classic paradigm of transcription regulation in bacteria

208 Growth of the Drosophila wing-a classic paradigm-is governed by two morphogens, Decapent

209 However, IDPs also follow some of the classic paradigms established for globular proteins, poi

210 our results are completely consistent with a classic parental effect, in which the environment experi

211 The synoviocytes producing IL-1beta (a classic pathogenic cytokine in osteoarthritis), mainly i

212 While most classic PCs belong to simple globular molecular systems,

213 tive and Comparative Biology, 23, 1983, 347) classic performance-morphology-fitness paradigm, we test

214 Barium (Ba(2+)) is a classic permeant blocker of potassium (K(+)) channels.

215 heterotrimeric G proteins, Galpha*betagamma Classic pharmacological methods, such as [(35)S]GTPgamma

216 firms the eruption occurred within the Early Classic phase when Maya expanded across Central America.

217 g interrogation of larger blood volumes than classic phlebotomy specimens over a prolonged period of

218 Combining classic physiology with modern molecular techniques, we

219 type distribution exists across Europe, from classic PKU in the east to mild PKU in the southwest and

220 The frequency of classic PKU increases from Europe (56%) via Middle East

221 ith the global phenotype distribution of 62% classic PKU, 22% mild PKU, and 16% mild hyperphenylalani

222 equal or higher number of genes compared to classic polyA[+] RNA-seq, including novel and non-polyad

223 Inflammatory bowel diseases are classic polygenic disorders, with genetic loads that ref

224 e pattern of weakness varied widely, and the classic pontobulbar palsy described in BVVL was not cons

225 Here we adapt a classic prey selection task from foraging theory to exam

226 The second area was the classic problem of prophage induction in response to cel

227 selectivity in our model is analogous to the classic proofreading mechanism originally proposed for t

228 Classic proteasomes are symmetric, with a regulatory ATP

229 pressing transit amplifying cells to produce classic psoriatic epidermal architecture.

230 Psilocybin is a classic psychedelic compound that may have efficacy for

231 Patients treated from 2004 to 2015 for classic PTC (cPTC) or AVPTCs were identified from the Na

232 The "classic" quantitative viral outgrowth assay (QVOA) has b

233 by showing how the simplest extension of the classic quaternary two-state allosteric model of Monod,

234 These responses revisit classic questions concerning mental representation and a

235 Next-gen VOA were compared to classic QVOA using single leukapheresis-derived samples

236 asensitive readout reported higher IUPM than classic QVOA.

237 ng MVP/MEK signaling axis independent of the classic Ras pathway may have important implications in t

238 tion on Stephen Kuffler's Oldies but Goodies classic reading list, with the hope that by looking back

239 trics particularly when there are coexisting classic regular bands.

240 xplore this, we used a modified version of a classic reinforcement learning task in which feedback in

241 , its focus also invites reappraisal of some classic research in order to address basic questions abo

242 Our findings suggest that many classic results on PTM cycles may not hold in vivo where

243 The classic rheumatogenic emm types represented only 12.3% o

244 r' accelerates deconvolution relative to the classic Richardson-Lucy algorithm by at least tenfold.

245 We simulated three models-a classic RL, a hierarchical RL, and a hierarchical Bayesi

246 choice serial reaction time task (5CSRTT), a classic rodent task often used to test sensory detection

247 MCs, beyond their classic role as master cells of allergic reactions, play

248 Further, in all classic scene and object regions, reachable-scale views

249 nt appears to be slightly higher than in the classic scheme of initial treatment of DTC.

250 Classic sensory systems rely on neuroepithelial circuits

251 conservation in the noncoding genome beyond classic sequence-level conservation.

252 , in addition to their conventional roles in classic sexual reproduction, contribute to adaptation of

253 gnaling to cell targets is unique, involving classic signaling (IL-6->IL-6R) cell membrane receptors,

254 We used the classic Simon task where participants hear the word "lef

255 ggregate behavior at larger scales mirrors a classic SIR-like pattern.

256 nile mice, which typically are excluded from classic social defeat experiments.

257 This binding site is different from that of classic sodium channel inhibitors like lidocaine, which

258 veal a disturbance response that presents as classic species sorting, but is nevertheless accompanied

259 heoretical approaches, we show here that the classic STDP rule in which pairs of single pre- and post

260 iptionally controlled by ATF3 in response to classic stimuli that promote heat generation in thermoge

261 trajectories spanning several days along the classic stratus-to-cumulus transition zone are stratifie

262 ification criteria lack specificity, and the CLASSIC study is underway to examine this area.

263 analyzing the predicted hardness of several classic superhard materials.

264 te deteriorates as prevalence decreases, and classic survey sampling strategies based on random sampl

265 h individual loci that are likely targets of classic sweeps and groups of genes that may have experie

266 evealed that treatment with dexamethasone, a classic synthetic glucocorticoid, enhanced survival of c

267 neuronal transport system, consisting of the classic system A transporters Slc38a1 and Slc38a2.

268 mphocytes, and of Mycobacterium-non reactive classic T(H)1 lymphocytes, with the residual populations

269 this protocol uses a combination of modified classic techniques, modern membrane filtration processes

270 ophila motor system as a model, we found the classic temporal transcription factor Hunchback acts in

271 stituent effects that cannot be described in classic terms.

272 hat discrimination reversal in macaques, the classic test of behavioral flexibility, is unaffected wh

273 Classic theoretical papers highlighted the importance of

274 Contrary to classic theories, recent work (McCormick et al.) has sho

275 The classic theory of direct-current (DC) insulator-based di

276 A classic theory proposes that plant xylem cannot be both

277 have failed to show benefits with respect to classic therapeutic interventions.

278 A classic thermodynamic mechanism predicts that if chemica

279 the 'bla(TEM-1B) type' prophages exhibited a classic Tn2 transposon structure with 100% sequence iden

280 lic carbonyl in the e-cigarette aerosol with Classic Tobacco flavor.

281 arked in a comparative evaluation with other classic tools on previously published well-characterized

282 layed kinetic parameters similar to those of classic TPSs.

283 We extend the classic transfer learning framework through ensemble and

284 Overall, the relative importance of the classic transmission route and alternate transmission ro

285 s of the renal glomerulus that result in the classic triad of heavy proteinuria, oedema and hypoalbum

286 Genetic anaemias lead us to reflect on the classic 'trolley dilemma', when there are two choices bu

287 d heritability estimates were obtained using classic twin design methodology in a sample of 2868 adol

288 Classic two-dimensional neural cultures present higher h

289 n in both cases being higher than that in a "classic" two-phase system.

290 of ACD, including the effector phase of the classic type IV hypersensitivity reaction.

291 ion as vertebrates, and contrasting with the classic understanding of open circulatory systems, have

292 nt methods achieve a higher performance than classic univariate and multivariate methods, supporting

293 the baseline method of listwise deletion to classic univariate and multivariate techniques.

294 d groups compared to results obtained from a classic untargeted metabolomics approach.

295 ntations, that would remain undetected using classic validation methods.

296 The classic view is that autoreactive T cells mistakenly des

297 Contrary to the classic view of maladaptive gene flow, our study reveals

298 tomy (in SI Appendix) doesn't always fit the classic view.

299 mposed of MGIT-PZA, pncA sequencing, and the classic Wayne test, was used.

300 ey are reminiscent of early reports from the classic yeast genetics literature, as well as recent stu