ライフサイエンスコーパス: clearance rate

1 is at diagnosis showed a significantly lower clearance rate.

2 atinine excretion then yields the creatinine clearance rate.

3 cal mechanisms that ultimately determine the clearance rate.

4 at is partially attributable to increased LH clearance rate.

5 erefore not represent a direct indication of clearance rate.

6 h the emission is regulated by mitochondrial clearance rate.

7 and insulin levels and an increased glucose clearance rate.

8 ucose tolerance tests showed a rapid glucose clearance rate.

9 (6)-DM1-High, with a slow overall whole-body clearance rate.

10 M1-High had the slowest blood and whole-body clearance rate.

11 abolically stable and displayed a low plasma clearance rate.

12 e cell body is stronger, leading to a higher clearance rate.

13 p levels than Cs, indicating reduced insulin clearance rate.

14 ty were established to improve relaxivity or clearance rate.

15 neutral or anionic liposomes have more rapid clearance rates.

16 lence with age is attributable to increasing clearance rates.

17 he design of synthetic heparins with desired clearance rates.

18 the tumor extracellular matrix, and systemic clearance rates.

19 uncertainty in the estimated acquisition and clearance rates.

20 mice with CAA, which corresponded to slower clearance rates.

21 moval is associated with up to >90% calculus clearance rates.

22 me lower over STIs, there were no changes in clearance rates.

23 CTL count and either viral rebound rates or clearance rates.

24 ine data on troponin T levels and creatinine clearance rates.

25 without mutation in the region showed normal clearance rates.

26 reasing continuous renal replacement therapy clearance rates.

27 ility in plasma free dobutamine and dopamine clearance rates.

28 min after agent administration by examining clearance rates.

29 human immunity is the primary determinant of clearance rates.

30 elop a relationship between bivalve size and clearance rates.

31 come measures were clinical and histological clearance rates.

32 e chemically stable, and have normal in vivo clearance rates.

33 A small difference in ethanol clearance rate (0.1 mg/ml/h) likely had little impact on

34 245 minutes (T 1/2 b; SD 76.min.); metabolic clearance rate = 0.65%/minute.

35 fferent continuous renal replacement therapy clearance rates: 1) no clearance (0 mL/kg/hr, to measure

36 The spontaneous viral clearance rate (18%) in this contemporary study was simi

37 resulting in a significantly higher glucose clearance rate (+21 +/- 2%).

38 uorouracil group also had higher complete AK clearance rates (38% vs 17% at 6 months) and fewer spot

39 asma concentration, 1.20 +/- 0.62 microg/mL; clearance rate, 6.33 +/- 6.41 L/h; elimination half-life

40 reasing continuous renal replacement therapy clearance rates (7.66 mL/min, 4.97 mL/min, and 2.67 mL/m

41 The cytoplasmic Ca(2+) clearance rate affects neuronal excitability, plasticity

42 The spontaneous viral clearance rate after 6 months of infection was 18% (95%

43 , which were associated with a slow parasite clearance rate after treatment with artemisinin derivati

44 Changes in transalveolar DTPA clearance rates after balloon occlusion of pulmonary art

45 The model estimated HDTX clearance rate agreed with in vitro literature values, s

46 Significant normalization of local DTPA clearance rates also occurred in the presence of a throm

47 There were no differences in clearance rates among the intravenous group, IVIG group,

48 the Thiele modulus are ratios of the plasma clearance rate and antibody catabolism, respectively, to

49 alities, including reduction of both glucose clearance rate and insulin sensitivity, as early as two

50 e is a positive relationship between maximum clearance rate and maximum ingestion rate.

51 highly significant correlation between VLDL clearance rate and mean atherosclerotic plaque size.

52 radioimmunotherapy by manipulating the blood clearance rate and the catabolism of the radiolabel.

53 ry the drug in living organisms with reduced clearance rate and toxicity.

54 The clearance rate and tumor-to-organ ratios were influenced

55 Literature-reported or predicted values for clearance rates and absorbed doses were used in the PK/P

56 essive regimen (n = 12), we calculated viral clearance rates and generation times and estimated the l

57 t transporter phosphorylation, enhanced 5-HT clearance rates and hyperserotonemia.

58 Estimates of clearance rates and liver and lesion uptake were made fo

59 s, we directly estimated viral expansion and clearance rates and overall infectiousness for each indi

60 interest such as biomarker intravasation and clearance rates and protein half-lives in the bloodstrea

61 depending on the patient-specific whole-body clearance rates and the times between fractions.

62 dimensional images of radionuclide kinetics (clearance rate) and cumulated activity.

63 ation was estimated as the reciprocal of the clearance rate, and acquisition rates were estimated on

64 Phase 1/2 declines, free virus clearance rate, and infected hepatocyte death rate were

65 say performance, false-negatives, rapid drug clearance rates, and difficulty in obtaining enough spec

66 response to PfEMP1, differences in parasite clearance rates, and heterogeneity in the rate at which

67 per minute) approached the rapid mucociliary clearance rates (approximately 2.0% per minute) reported

68 eatment with amiloride increased mucociliary clearance rates (approximately twofold) after inhalation

69 e-water distribution coefficients, and renal clearance rate are among the most important model parame

70 irways airway surface liquid (ASL) depth and clearance rates are both increased by fluid secretion.

71 Our estimates of progression and clearance rates are consistent with the findings of surv

72 ripsy success rates vary from 50 to 90%, but clearance rates are often delayed.

73 ent glycans in the Fc region showed the same clearance rate as demonstrated previously.

74 These slow clearance rates associate with enhanced survival rates o

75 Creatinine clearance rate at 6 months and 3 years and chronic allog

76 Human papillomavirus 16/18 clearance rates at 12 months were 48.8% (86/177) in the

77 ar metabolic enzyme activities and metabolic clearance rates between red- and white-blooded Antarctic

78 wever, dynamic PET did not show differential clearance rates between treatment and control groups.

79 ng demonstrated a marked difference in brain clearance rates between wild-type and mrp1 knockout mice

80 arasite genetics is associated with parasite clearance rate but does not account for all variation.

81 ice) displayed comparable vaginal chlamydial clearance rates but significantly reduced oviduct pathol

82 ce effects at the physiological level (algal clearance rate), but induced DNA damage, as determined b

83 Mechanistically, decorin increased the VEGFA clearance rate by augmenting autophagic flux, a process

84 We measured heritability of clearance rate by evaluating patients infected with iden

85 Notably, clearance rates by 24 months were 41% and 94% in the hig

86 where F is the RBF, k is the tissue-to-blood clearance rate, C is the PET concentration, and C(a) is

87 r the accelerated radioaerosol transalveolar clearance rates caused by acute balloon occlusion of the

88 ion was rapid, with a half-life and systemic clearance rate (Cl(S/F)) averaging 1.8 hours and 115 mL/

89 The absolute oral bioavailability (F), clearance rate (CL), average blood concentration (C[av])

90 Mean particle clearance rate (Clr in %/min) through 50 min for placebo

91 nd 28 days after injection and delayed blood clearance rates compared with native AAV.

92 demonstrated the highest participant partial clearance rates compared with placebo (risk ratio, 7.12;

93 1), which was very similar to the mean viral clearance rate constant after drug resumption of 0.35 (0

94 The k'2 (clearance rate constant from the reference region) requi

95 decline with a minimum estimate of the viral clearance rate constant of 2.8 per day, corresponding to

96 Virion clearance rate constants were 0.0063/min (9.1/day) to 0.

97 (11)C-acetate clearance rates correlated moderately with quantitative

98 sinin resistance results in reduced parasite clearance rates (CRs) after treatment.

99 Accurate measurement of malaria parasite clearance rates (CRs) following artemisinin (ART) treatm

100 Incidence rates (IRs) and clearance rates (CRs) of incident anal hrHPV infections

101 A faster pulmonary clearance rate did not simply reflect the presence of ch

102 The clearance rate, dissolved uptake rate (for Cd and Zn), a

103 Mean baseline peripheral clearance rates during the first 40 min of clearance mea

104 in sensitivity index Stumvoll, and metabolic clearance rate estimation without demographic parameters

105 However, this clearance rate excludes the highly variable lag phase, w

106 duced TG levels by increasing the fractional clearance rate (FCR) of VLDL TGs from the circulation, w

107 intensity versus time data, and fluorescence clearance rate (FCR) was extracted from the second (term

108 received their own LDL), the LDL fractional clearance rate (FCR) was reduced in fish oil-supplemente

109 At the end of each period, fractional clearance rates (FCRs) and production rates (PRs) of apo

110 tic consumption is associated with increased clearance rate for both susceptible and resistant strain

111 vels of ManR and ASGR expression control the clearance rate for glycoproteins bearing recognized glyc

112 administration increased the basal metabolic clearance rate for leucine (approximately 28%, P < 0.05)

113 In this study, we measured in vitro hepatic clearance rates for 50 IOCs using a pooled batch of live

114 Clearance rates for both Abeta42 and Abeta40 were impair

115 Clearance rates for C12-IOCs were higher than those for

116 We have shown that clearance rates for glycoproteins such as luteinizing ho

117 Clearance rates for HPV-16/18 infections at 6 months wer

118 the literature by estimating progression and clearance rates for non-16 and non-18 high-risk types.

119 the charged terminal group, with the highest clearance rates for tertiary amines and sulfates and no

120 The fungal clearance rate from cerebrospinal fluid was similar betw

121 The clearance rate from the circulation was increased with t

122 lky dibenzocyclooctyne group in AP decreased clearance rates from circulation.

123 and (131)I-labeled fragments revealed blood clearance rates from slowest to fastest as follows: wild

124 , endogenous glucose production, and glucose clearance rate (GCR).

125 % CI, 1.002-1.017; P = .01) and a creatinine clearance rate >/=53 mL/min (OR, 1.024; 95% CI, 1.006-1.

126 Only baseline creatinine clearance rate >/=53 mL/min predicted 6-week survival (P

127 common solution to estimate acquisition and clearance rates has been to assume a fixed genetic dista

128 es of TG mice exhibited normal basal glucose clearance rates; however, under insulin-stimulated condi

129 slightly better than 3/3 VLDL, but the VLDL clearance rate in 4/4 mice was half that in 3/3 mice.

130 P = .03; ASMQ, P = .09), but negatively with clearance rate in both study arms (AL, P = .16; ASMQ, P

131 onsistent with this idea, we found that 5-HT clearance rate in hippocampus was dramatically reduced i

132 sensitivity mediated by an increased glucose clearance rate in insulin-responsive tissues under insul

133 The slow clearance rate in men (based on 6 months' follow-up) was

134 ed that MG(min)-LDL had a similar fractional clearance rate in plasma to unmodified LDL but increased

135 with the data examined here for the in vivo clearance rate in the rat.

136 me scale of minutes, we determine the plasma clearance rate in the wild-type mouse, using time-resolv

137 estern Cambodia, detected as a slow parasite clearance rate in vivo.

138 ta34 levels correlate with the overall Abeta clearance rates in amyloid positive individuals.

139 motif showed remarkably reduced circulatory clearance rates in an animal model.

140 try (chronoamperometry) to examine serotonin clearance rates in brain liposomes (synaptosomes) prepar

141 gnificance is expected to be increased mucus clearance rates in cholinergically stimulated airways.

142 Lower viral clearance rates in circulating blood may explain the phe

143 ; however, it does not account for prolonged clearance rates in patients without detectable viremia.

144 vWF clearance rates in rat plasma were determined by quantit

145 measured Abeta42 and Abeta40 production and clearance rates in the CNS of participants with Alzheime

146 ked vascular responses resulted in increased clearance rates in the visual cortex of awake mice.

147 Absence of SLC10A4 led to slower dopamine clearance rates in vivo, which resulted in accumulation

148 haride structures in the Fv region and their clearance rates in vivo.

149 e were no differences in plasma TG turnover (clearance rate) in response to either treatment, consist

150 The blood glucose clearance rate increased significantly at day 20 (P < 0.

151 Clearance rates increased with CeO2 concentration but de

152 Clearance rates increased with year of age, adjusted for

153 increased SIV infectivity, a decreased viral clearance rate, increased viral load, and higher CD4(+)

154 parasite survival rates and in vivo parasite clearance rates indicate that K13-propeller mutations ar

155 dition, basal and insulin-stimulated glucose clearance rates into insulin-sensitive peripheral tissue

156 ial proportion (56%-58%) of the variation in clearance rate is explained by parasite genetics.

157 e DMPC gel-to-liquid crystal transition, the clearance rate is independent of the protein helical con

158 lications for both dose level and frequency, clearance rate is one of the most important pharmacokine

159 Our estimated clearance rate is slower than previously assumed.

160 Both (11)C-acetate clearance rates, K(mono) (R(2) = 0.41, P = 0.006) and k2

161 Chlamydial clearance rates, local Th1 cytokine production, and host

162 Clearance rate magnitudes estimated from flow visualizat

163 essive efficacy, together with the increased clearance rate, makes Lm-RIID ideal for prophylactic imm

164 ility is high, the genes underlying parasite clearance rate may be identified by genome-wide associat

165 idation, glucose carbon recycling, metabolic clearance rate (MCR) and non-oxidative disposal of gluco

166 Similarly, the metabolic clearance rate (MCR) in the control group increased 72%

167 -time (min) based on an exponential fit, and clearance rate (%/min) based on a linear fit.

168 The primary endpoints were duct-clearance rates, morbidity, operating time, and hospital

169 ing of lymphatic drainage patterns, particle clearance rates, nodal metastases, and differential tumo

170 receiving any sertraline dose averaged a CSF clearance rate of -0.37 colony forming units per mL per

171 DX-8951f had a half-life of 7.15 hours and a clearance rate of 1.65 L/h.m(2).

172 and 89% oral bioavailability and an in vivo clearance rate of 19.5 mL/min/kg in the rat.

173 wer at rest in contractile reserve-negative (clearance rate of [11C]acetate, 0.043+/-0.012 min(-1)) t

174 total-body radiation dose (TBD) based on the clearance rate of a preceding dosimetric dose.

175 wever, recent data also indicate a decreased clearance rate of Abeta in AD brains.

176 outcome was 2-week cerebrospinal fluid (CSF) clearance rate of cryptococcus, termed early fungicidal

177 The clearance rate of dense vesiculated RBC was biphasic and

178 quantitative time-series data showed a mean clearance rate of Ebola virus RNA from seminal fluid of

179 The permeability of PMEM was assessed by the clearance rate of Evans blue-labeled albumin, the activa

180 elta, loss rate of virus-producing cells; c, clearance rate of free virions; tau, delay until viral d

181 -based assessment indicated that the hepatic clearance rate of freely dissolved chemicals was similar

182 The rapid clearance rate of HCV(VLDF) indicates that association w

183 The clearance rate of hGH in rats was inversely proportional

184 two factors: insulin secretion and metabolic clearance rate of insulin (MCR(I)).

185 72 h of physiologic hyperglycemia, metabolic clearance rate of insulin was markedly reduced (P < 0.01

186 insulin resistance, and 3) reduces metabolic clearance rate of insulin.

187 he lungs of WT mice markedly accelerated the clearance rate of P. aeruginosa, demonstrating that lung

188 learning approach and found that the immune clearance rate of persister cells is a key feature.

189 o manipulate the in vivo biodistribution and clearance rate of polyethylene glycol-based bottlebrush

190 ificant association was detected between the clearance rate of productively infected cells and freque

191 gues at early times after injection, but the clearance rate of radioactivity from brain tissue varied

192 The fractional clearance rate of radiolabeled LDL was reduced to simila

193 sed swallowing frequency, thus improving the clearance rate of reflux within the esophagus.

194 The clearance rate of small HDL3 particles (density>1.13 g/m

195 Clearance rate of the remaining 62 patients was 100%.

196 cell-surface expression; but given the high clearance rate of thrombin, the high concentration of da

197 At the MTD, the median clearance rate of ultrafiltrable platinum was 9.7 L/h/m2

198 An endotoxin clearance rate of up to 1.3 x 10(8) was attained.

199 ting satellite species, although the overall clearance rate of vWF antigen was similar to wild type v

200 glomerular size selectivity by measuring the clearance rates of 3000- and 70,000-Da fluorescence-neut

201 easurements of the fractional production and clearance rates of Abeta in vivo in the human CNS to be

202 The high incidence and low clearance rates of anal HPV16 infection, compared to oth

203 lic control (BUNs = 60 mg/dl), required urea clearance rates of approximately 900 ml/h and 1900 ml/h

204 a remarkable ability to predict in vivo drug clearance rates of both rapid and slow clearing drugs wi

205 ce are influenced by both the production and clearance rates of CEA.

206 The clearance rates of cellular reservoirs could not be dist

207 Clinical trials use clearance rates of circulating parasites as their clinic

208 ased hepatic fatty acid synthesis, increased clearance rates of dietary triglycerides and increased h

209 estion of tolbutamide changed the calculated clearance rates of endogenously secreted insulin.

210 We compared the plasma concentrations and clearance rates of four solutes normally cleared by tubu

211 in genital mucosa, the in vivo expansion and clearance rates of HSV-2 are extremely rapid.

212 r, control and Pompe iPSC-CMs had comparable clearance rates of LC3-II-detected autophagosomes.

213 slower second component consistent with the clearance rates of normal control populations.

214 Clearance rates of NT-proET-1, ELDP and CT-proET-1 were

215 We sought to compare clearance rates of plasma human immunodeficiency virus t

216 s the effects of drugs on the production and clearance rates of proteins targeted as potential diseas

217 ibe a method to determine the production and clearance rates of proteins within the human central ner

218 climatic conditions on both acquisition and clearance rates of the bacterium, finding significantly

219 significantly reduced both the amplitude and clearance rates of the MPP(+)-evoked dopamine signal in

220 The biodistribution and clearance rates of the substrates are therefore directly

221 riability in mAb clearance is due to varying clearance rates of these different circulating CEA subsp

222 Rigorous estimates for clearance rates of untreated chlamydia infections are im

223 secretion with the plasma concentrations and clearance rates of urea and creatinine in patients recei

224 and apo B production rates were normal, but clearance rates of VLDL triglycerides and postlipolysis

225 tDNA detection rate and (ii) sustained ctDNA clearance rate on pembrolizumab (NCT03145961).

226 linical cure, bacteriological cure, pathogen clearance rate or bacterial load.

227 .9 mmol/l), women with GDM had lower glucose clearance rates (P = 0.0001) but higher glucose producti

228 roduction rates (P = 0.01) but lower glucose clearance rates (P = 0.001) compared with normal pregnan

229 s, we also quantified the average creatinine clearance rate per glomerulus.

230 Despite comparable reductions in LDL clearance rates, plasma LDL levels are substantially low

231 herapy values, platelet count and creatinine clearance rate, predict IA outcome and stratify patients

232 nce (r = 0.51, P < 0.01), and the free water clearance rate (r = -0.90, P < 0.002).

233 duction of E. coli over 24 h, and calculated clearance rates ranged from 1.2 to 7.4 L hr(-1) bivalve(

234 ctly to the testis and has a rapid metabolic clearance rate, reducing the length of exposure in the l

235 n and carbachol, which produced near-maximal clearance rates regardless of prior treatment with CFTR

236 The dialytic clearance rates (relative to normal subjects) of unbound

237 compared to controls (55.6, 22.2, and 33.3% clearance rates, respectively).

238 odest but continual enhancement of reservoir clearance rates result in faster cure than abrupt, one-t

239 evelopment, and Evaluation, ++--) and lesion clearance rates (risk ratio, 2.97; 95% confidence interv

240 gery showed the highest participant complete clearance rates (risk ratio, 7.73; 95% confidence interv

241 ding assays demonstrate an identical vesicle clearance rate shared by both the mutant and the wild-ty

242 the transgenic mice had glucose turnover and clearance rates similar to the controls, but showed a lo

243 G6 dendrimers also showed decreased renal clearance rate, slightly increased liver and spleen upta

244 the dynamics are primarily determined by the clearance rates, steady-state concentrations and respons

245 and, in the individual cases, unpredictable clearance rates suggest the necessity of dosimetry-based

246 mice, we failed to detect any differences in clearance rates, suggesting that differences in plasma a

247 rtles and examine potential impacts on toxin clearance rates, symptom reduction, rehabilitation time,

248 cin (Alzal Corp, Palo Alto, CA) has a slower clearance rate than free doxorubicin, resulting in susta

249 lacking galactosylation had slightly faster clearance rates than other structures in the Fv domain.

250 ad lower free plasma dobutamine and dopamine clearance rates than those patients with serum creatinin

251 sinusoidal endothelial cells and a gammaDPGA clearance rate that was more rapid than the clearance re

252 that contained only structural proteins had clearance rates that were significantly higher than vacc

253 tomized or propranolol-treated rats revealed clearance rates that were the same or less than normal,

254 TPase alpha2) mice, which have reduced Na(+) clearance rates that would favor NCX1 reverse-mode opera

255 For different reinfection incidence and clearance rates, the model evaluated the accuracy of epi

256 te similar or lower viral titers and similar clearance rates, the variants caused more extensive dise

257 ngorged lysosomes and a slower autophagosome clearance rate upon autophagy induction by starvation.

258 The clearance rate was 0.032 episodes/day (95% confidence in

259 Mucus clearance rate was 11.3 +/- 9.9 mm/min in the Trendelenb

260 (5.2) mL/min and the mean plasma creatinine clearance rate was 20.7 (4.8) mL/min.

261 The mean plasma urea clearance rate was 22.7 (5.2) mL/min and the mean plasma

262 Maximal cAMP-dependent alveolar fluid clearance rate was 32.9 +/- 10.9 %/hr (p <.05).

263 The 3-year histological clearance rate was 81.8% (9/11) for lesions >10 mm, and

264 The histological clearance rate was 89.5% and 84.2%, respectively, at 3 a

265 When the creatinine clearance rate was considered as a continuous variable a

266 this effect of repeated swim to reduce 5-HT clearance rate was corticosterone dependent, as evidence

267 The spontaneous HCV clearance rate was found to be 33.1%.

268 In Pak2(-/-) mice, platelet clearance rate was increased, as was production of newly

269 Mucus clearance rate was measured through fluoroscopic trackin

270 By measuring clearance rates, we determine that Shh has an extracellu

271 progression to high-grade SIL (HSIL) and the clearance rate were estimated at lesion level.

272 ogression to high-grade SILs (HSILs) and the clearance rate were estimated at the lesion level.

273 Significant differences in the spontaneous clearance rate were estimated between age categories and

274 (-/-) mice, tear production, osmolarity, and clearance rate were evaluated before and after experimen

275 0.3 min) and slow (T1/2 = 10.9 +/- 1.4 min) clearance rates were accelerated (p < 0.0001) in Group 5

276 Free dobutamine and dopamine clearance rates were calculated.

277 Clearance rates were conveniently monitored by quantitat

278 Clearance rates were especially high in patients with co

279 Serotype-specific clearance rates were estimated by exponential regression

280 Clearance rates were initially high then declined slowly

281 Subsequently, mucociliary clearance rates were measured by gamma scintigraphy of i

282 excretion rates and GFR determined by inulin clearance rates were measured during each of three treat

283 FDG clearance rates were measured in both normal and phloriz

284 Alveolar fluid clearance rates were measured in ex vivo perfused human

285 Tear clearance rates were measured with a fluorophotometer.

286 VLDL1, VLDL2, and CM TAG clearance rates were not different between groups.

287 To explain why parasite clearance rates were not faster with split dose regimens

288 Body weight, BP, and creatinine clearance rates were not significantly different among t

289 Interpatient variations in serum clearance rates were observed and were secondary to diff

290 Interpatient variations in serum clearance rates were observed and were secondary to diff

291 liver, although slightly different vascular clearance rates were observed.

292 These clearance rates were significantly higher at each time-p

293 ta confirmed that the plasma drug levels and clearance rates were similar for patients in both groups

294 Clearance rates were used to impute the proportion of un

295 ance and disappearance, as well as metabolic clearance rates, were lower in the MHD group at 30 and 6

296 gnments than those scenarios using predicted clearance rates, when comparing to bin placement using l

297 ducing the geometric collision kernel to the clearance rate, which we model accurately by superposing

298 viral load and elevated antiretroviral drug clearance rates, which pose significant therapeutic chal

299 n the structure of these molecules and their clearance rate will further our ability to produce immun

300 duals could potentially exhibit altered SAHA clearance rates with differences in overall response.