ライフサイエンスコーパス: cleaved

1 ed using a precursor tag that is tracelessly cleaved.

2 Hg(2+), the CS-C(9) bond in the sensor gets cleaved.

3 roducts rather than where the substrates are cleaved.

4 anism where mismatches can be bound, but not cleaved.

5 H IgG1, which led to the formation of single cleaved 5B9 (sc5B9), without any reduction in binding ab

6 INF2 is proteolytically cleaved, a process mediated by cathepsin proteases, libe

7 The recombinant enzymes cleaved alginates endolytically (CaAly1, CaAly2, CaAly3)

8 blot hybridization and reverse-transcription cleaved amplified polymorphic sequence analysis), genomi

9 hin the periphery of these granulomas, while cleaved amyloid beta (Abeta) peptides accumulate around

10 PAR4 is a member of this family that is cleaved and activated by serine proteinases such as thro

11 a on macrophages and activated platelets was cleaved and activated by thrombin, while tissue factor,

12 CaCu[Formula: see text]O[Formula: see text], cleaved and annealed in ozone to increase the doping all

13 inases 2 and 9, the coiled-coil peptides are cleaved and antigen binding is restored.

14 er, in the presence of E. coli LL37(FRRV) is cleaved and can no longer affect the conformations and o

15 seful for identification of the class of RNA cleaved and consensus sequences required for accurate su

16 dition, we find that phospho-PLK4 (pPLK4) is cleaved and distributed to kinetochores (metaphase and a

17 igma3 is proteolytically degraded and mu1 is cleaved and exposed to form infectious subvirion particl

18 a suppressor of cytokine production that is cleaved and inactivated by caspase-8.

19 lation (pA) sites at which precursor mRNA is cleaved and polyadenylated, allows cells to quickly resp

20 NA moiety of CD30-AshR-RORgammat chimera was cleaved and released by Dicers.

21 secretory component (SC), is proteolytically cleaved and released either unbound (free SC) or bound t

22 Its extracellular domain can be cleaved and released into the circulation as soluble ENG

23 an acidic environment, the acetal groups are cleaved and the gold nanoparticles become highly water-s

24 spase-3/7, the water-soluble peptide DEVD is cleaved and the remaining Gd(III)-AIEgen (Gad-AIE) conju

25 Calcineurin is cleaved and thereby activated by calpain proteases, whic

26 M structures for RaTG13 S and for both furin-cleaved and uncleaved SARS-CoV-2 S; we compared these wi

27 as a preprohormone which is proteolytically cleaved, and acylated by a membrane-bound acyl transfera

28 ocess, aromatic C-H and amidic C-N bonds are cleaved, and new C-C and C-N bonds are formed in a step-

29 , complement component C4 is proteolytically cleaved, and the major product C4b is deposited on the a

30 on procedure, disulfide bonds are chemically cleaved, and the perfluoroalkyl chains are removed from

31 , followed by beta1-3,4 galactosidase, which cleaved any terminal alpha2-3-linked sialic acid and und

32 proRaxX is cleaved at a Gly-Gly motif, yielding a mature peptide th

33 HA of most influenza viruses is cleaved at a monobasic cleavage site, and a number of pr

34 most influenza A and B (IAV/IBV) viruses is cleaved at a monobasic motif by trypsin-like proteases.

35 accompanied by the accumulation of ribosomes cleaved at helix 69 (H69) of the 26S ribosomal RNA (rRNA

36 hey fold up into a hairpin structure that is cleaved at its base by an enzyme complex known as the Mi

37 Following secretion, IvaP is cleaved at least three times to yield a truncated enzyme

38 wo overlapping large polyproteins, which are cleaved at specific sites by a 3C-like cysteine protease

39 replication-dependent histone pre-mRNAs are cleaved at the 3' end by U7 snRNP consisting of two core

40 found that the ATP used in this reaction is cleaved at the alpha-phosphate position by SidJ, which-i

41 ion of O-glycoprotein yields O-glycopeptides cleaved at the N-terminal end of serine and threonine, w

42 ring encloses the transmembrane anchors for cleaved ATP6AP1/Ac45 and ATP6AP2/PRR, the latter of whic

43 Active caspase-6 cleaved Bid to induce cytochrome c release, generating a

44 s during the unfolding of five helices of EF-cleaved bR.

45 PARP-1 was not cleaved but over-activated under AEBP1 down regulation w

46 he bond dissociation energy of the C-H bonds cleaved by 4 (92 kcal/mol) is comparable to C-H bonds cl

47 roRNA sequences which are not preferentially cleaved by 8-17.

48 e-forming activity of its N-terminal domain, cleaved by activated caspases associated with the releas

49 After VSV infection, HIPK2 was cleaved by active caspases, which released a hyperactive

50 , we find that neurexin-1 is physiologically cleaved by ADAM10 similar to its ligand neuroligin-1, wi

51 at VGF secreted from early infected cells is cleaved by ADAM10, after which it acts largely in a para

52 This APP domain contains the sites cleaved by beta- and alpha-secretases: our data suggest

53 otics act on bacterial cell walls and can be cleaved by beta-lactamases.

54 ion from the vicinity of the target DNA site cleaved by Cas9.

55 milial ageing-related hearing loss(2)-can be cleaved by caspase 3, thereby converting noninflammatory

56 During apoptosis, the C-terminal tail is cleaved by caspase, allowing the release of ATP through

57 MD) in inflammasome-activated macrophages is cleaved by caspase-1 to generate N-GSDMD fragments.

58 The substrates that are cleaved by caspase-8 to prevent necroptosis in vivo have

59 GSDMC is specifically cleaved by caspase-8 with TNFalpha treatment, generating

60 ferrocene label as the peptide molecules are cleaved by cathepsin B.

61 nstrated that the peptide-cargo conjugate is cleaved by cells in the epithelium at the site of a two-

62 owing endocytosis of EBOV, the GP1 domain is cleaved by cellular cathepsins in acidic endosomes, remo

63 Notably, both TrkB and APP are robustly cleaved by delta-secretase in AD brains, accompanied by

64 In this study, N-glycans were sequentially cleaved by enzymes at the head of the separation capilla

65 though the S1-S2 linker of WT Kv1.5 could be cleaved by extracellularly applied proteinase K (PK), an

66 sc cells express Bnl as a proprotein that is cleaved by Furin1 in the Golgi.

67 cumulate in allograft tissue, where they are cleaved by granzyme B, releasing a fluorescent reporter

68 irions traffic to late endosomes where GP is cleaved by host cysteine proteases.

69 ne dimer, the substrate was less efficiently cleaved by human RNase H2.

70 y 4 (92 kcal/mol) is comparable to C-H bonds cleaved by IPNS (93 kcal/mol).

71 e carrying a mutated p85alpha that cannot be cleaved by LF show a greater resistance to anthrax toxin

72 was important for its antiviral activity and cleaved by MCPIP1 in the cell-free system.

73 Since PrP(C) is cleaved by members of the disintegrin and matrix-metallo

74 pon reaching the tumor, the outer domain was cleaved by membrane type-serine protease 1 (MT-SP1) pres

75 d to form a pore in cell membranes only when cleaved by MMPs (to form PA-L1).

76 lectively quantify other endogenous peptides cleaved by peptidases whose concentrations are below 1 p

77 r the previously described substrate breadth cleaved by sialidases in human vaginal specimens of wome

78 ring these stalled ribosomes are selectively cleaved by specific RNases, leading to their preferentia

79 stabilization of the carboxylate group being cleaved by the enzyme.

80 Since PACAP peptide is cleaved by the human membrane neprilysin hNEP, we search

81 only activating receptor on NK cells that is cleaved by the metalloprotease a disintegrin and metallo

82 s produced as inactive proform and has to be cleaved by the multiprotein complex inflammasome to be a

83 s imported into depolarized mitochondria and cleaved by the OMA1 protease.

84 five continuous ribonucleotides which can be cleaved by the ribonuclease to specifically initiate DNA

85 oluene alters which C-O bonds in a sugar are cleaved by the tris(pentafluorophenyl)borane/HSiR(3) cat

86 uroligin-1 and neuroligin-2 are not directly cleaved by this pathway, when heterodimerized with neuro

87 helial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases genera

88 ide, S16, that was robustly and specifically cleaved by tumor-associated metalloproteinases in the Hi

89 tion initiation factor 4 gamma I (eIF4GI) is cleaved by viral protease 2A.

90 ide, which could temporarily inhibit, and be cleaved by, the purified enzyme.

91 Rapid C4 activation and capsid deposition of cleaved C4b are catalyzed by antibodies via the classica

92 PP) and is specifically mediated by the beta cleaved carboxy terminal fragment of APP (APP-betaCTF, C

93 diated by elevated levels of endogenous beta-cleaved carboxy-terminal fragment of APP (APP-betaCTF).

94 we found that STAT3 interacts with a calpain-cleaved carboxyl-terminal fragment of FLNA.

95 formation) followed by extrinsic apoptosis (cleaved CASP8/3 [caspase-8/3] and PARP [poly(ADP-ribose)

96 DRG neurons showed accumulation of cleaved caspase 3 (apoptosis) and nuclear-localized acti

97 TTC7A-KO cells contained cleaved caspase 3 and had reduced levels of phosphorylat

98 mediated dUTP nick-end labeling staining and cleaved caspase 3 expression.

99 of RPS6KB1 and Ki-67 and increased levels of cleaved caspase 3 in tumor tissues.

100 ergic neurons predominantly colocalized with cleaved caspase 3 staining.

101 is article, we report an assay that measures cleaved caspase 3 to define clonal deletion at the popul

102 In support of this, activated Bak and cleaved caspase 3 were detected in astrocytes within reo

103 increased levels of phospho-p53, total p53, cleaved caspase 3, ERK1/2 and phospho-AKT in white indiv

104 apoptosis, including BIM, cleaved PARP, and cleaved caspase 3.

105 NA assessment, and Western blot analysis for cleaved caspase 3.

106 horylated AKT and XIAP and reduced levels of cleaved caspase 3.

107 e ethanol exposure prevented accumulation of cleaved caspase-3 (CC3) and hyperphosphorylated tau (PHF

108 also increased expression of Bax as well as cleaved caspase-3 and -PARP in colon cancer cells by dow

109 d levels of gamma-H2AX, Bcl-2/Bax, TNFalpha, cleaved Caspase-3 and poly ADP-ribose polymerase (PARP).

110 Immunohistochemical analysis of Ki67 and cleaved caspase-3 confirm these findings from in vivo im

111 f 13 matched pairs; P < 0.001) and increased cleaved caspase-3 confirmed apoptotic activity.

112 F-induced barrier loss, along with increased cleaved caspase-3 production.

113 M) (-/-) skeletal muscle and the presence of cleaved caspase-3 suggested myocyte apoptosis.

114 Here, we studied the role of cleaved caspase-3 using human- and mouse-proficient casp

115 dingly, dying endothelial cells that contain cleaved caspase-3 were abnormally abundant in yolk sacs

116 proapoptotic proteins such as PUMA, Bax, and cleaved caspase-3 were all significantly increased in C9

117 me B, perforin-1, Fas ligand) and apoptotic (cleaved caspase-3) effector molecules.

118 ess response (GRP78 and CHOP) and apoptosis (cleaved caspase-3) were elevated in diabetic myocardium.

119 ated animals showed significantly lower ROS, cleaved caspase-3, and cytochrome c activities, leading

120 egulation of the pro-apoptotic proteins Bax, cleaved caspase-3, and downregulation of the anti-apopto

121 rimental PARylation, increased expression of cleaved caspase-3, and increased gammaH2AX foci.

122 age in tumors, shown by strong expression of cleaved caspase-3, and leads to a prolonged median survi

123 XIAP) and reduced the levels of gamma-H2AX, cleaved caspase-3, and thrombospondin-2 (THBS2) implicat

124 In addition, both cleaved caspase-3-positive neurons and TUNEL-positive ne

125 DNA fragmentation, TUNEL-positive neurons, cleaved caspase-3-positive neurons, translocation of mit

126 gered the persulfidation and deactivation of cleaved caspase-3.

127 ed cell apoptosis and the elevated levels of cleaved caspase-3.

128 rs had increased expression of gammaH2AX and cleaved caspase-3.

129 ctions of THBS1 on cell viability, XIAP, and cleaved caspase-3.

130 numbers of monocytes positive for TUNEL and cleaved caspase-3.

131 PRL also reduced active cleaved-caspase-1 levels independent of pannexin-1 activ

132 ng a caspase-recruitment domain), and active cleaved-caspase-1, which are components of the NLRP3 inf

133 OD activity;si-TTP upregulated pro-apoptotic cleaved-caspase-3 expression, and downregulated antiapop

134 Levels of cleaved CCN3, an antifibrotic protein, were lowered in H

135 Cleaved CDCP1 isoform (70 kDa) was expressed to a varyin

136 sistant to cleavage and gene conversion with cleaved copies-the Rescue-provides essential gene functi

137 gation of the magnetism of micromechanically cleaved CrCl(3) flakes with thickness >10 nm is performe

138 We find that the cleaved CTT of PC1 (PC1-CTT) stimulates the transcriptio

139 Serum cleaved cytokeratin 18 and caspase-3/7 decreased signifi

140 43) and caspase-dependent apoptosis (caspase-cleaved cytokeratin-18) compared to control; caspase-dep

141 an A1A2A3 tridomain fragment of VWF, plasmin-cleaved dimers of VWF, multimeric recombinant VWF, and n

142 Because Cas9 can remain stably bound to the cleaved DNA for hours, its postcatalytic conformation ma

143 ge complexes with double- or single-stranded cleaved DNA.

144 II alone, in specific complex with partially cleaved dsDNA, and in scanning complex with an RNA/DNA h

145 The RNase L-cleaved dsRNAs signal to Rig-like helicases to amplify I

146 We demonstrate that ENTR1 is cleaved during Fas-induced apoptosis in a caspase-depend

147 HAZV nucleocapsid protein arm domain that is cleaved during HAZV infection, for which the equivalent

148 nt, also produces a self-cleaving RNA and is cleaved during T-cell activation as well as thermal and

149 hesized as a precursor (pre-proSP-B) that is cleaved during trafficking into three related proteins.

150 aining of DCLK1 and active beta-catenin, and cleaved E-cadherin.

151 ystal structure of ADI-15946 in complex with cleaved Ebola virus glycoprotein (EBOV GP(CL)) reveals t

152 Thus, in the presence of BMS-806, the cleaved Env on the surface of cells and virus-like parti

153 gulatory mechanism of Robo and show that the cleaved extracellular fragment of Robo can function as a

154 on molecule SYG-1/Neph as a receptor for the cleaved extracellular Robo fragment to mediate glial mig

155 ded to and was sufficient for the ability of cleaved factor V to bind Xa and assemble into the prothr

156 that N-terminal GPS/GAIN cleaved PC1 and PPC cleaved fibrocystin ectodomains can be released under no

157 There, they are cleaved first by S1P and then by S2P, liberating their N

158 ted to less conformational constrains of the cleaved form comparedtointact, as suggested by the 2-fol

159 This cleaved form of RILP promotes the movement of multivesic

160 we analyse the binding of ACE2 to the furin-cleaved form of the SARS-CoV-2 spike protein using cryo-

161 e latter occurring mainly in proteolytically cleaved form, as membrane-spanning C-terminal fragments

162 rotein more pronounced than for than for the cleaved form.

163 ) and fully reduced (all disulfide bonds are cleaved) forms.

164 ing a peptide and selectively separating the cleaved fragments in different daughter droplets on the

165 t time that in humans, [Pyr(1)]apelin-13 was cleaved from both termini but the C-terminal was more su

166 The 2-phenylisopropyl group can be cleaved from carboxyl with 2-3% (v/v) of TFA in acetonit

167 soluble chemokine, CX3CL1 (fractalkine), is cleaved from membrane-bound CX3CL1 by proteases includin

168 by analyzing glycan structures enzymatically cleaved from RNase-B.

169 , the fluorinated side chains will be slowly cleaved from the backbone of the side-chain fluorinated

170 scence microscopy was performed on oligomers cleaved from the beads, and it revealed that (i) oligome

171 sor protein (APP), PrP(C) is proteolytically cleaved from the cell surface by a disintegrin and metal

172 a toxic C-terminal region (CdiA-CT) that is cleaved from the effector upon transfer into the peripla

173 The HpSGN system cleaved genomic DNA at an efficiency of ~40% and ~20% in

174 We show that the cryogenic IR spectra of the cleaved glycans are highly structured and virtually iden

175 Cleaved GP then binds its cellular receptor, Niemann-Pic

176 NPC1 binding to cleaved GP1 is required for entry.

177 nd small-molecule agonists can activate only cleaved GPR56.

178 Cleaved GSDMD forms membrane pores, leading to cytokine

179 We establish cleaved HAC1 mRNA as endogenous substrate for ribosome-a

180 re, we observe reduced plasma prekallikrein, cleaved high molecular weight kininogen and elevated pla

181 Plasma concentrations of cleaved high-molecular-weight kininogen (cHK), vascular

182 duced by the presence of a portal complex in cleaved HK97 proheads.

183 Thrombin-cleaved IL-1alpha was detected in humans during sepsis,

184 -1 and maturation of pro-IL-1beta to secrete cleaved IL-1beta both in mouse lungs and in primary type

185 three SAM S-C bonds can be regioselectively cleaved in an RS enzyme.

186 ster bond of nucleic acids is hydrolytically cleaved in critical biological processes.

187 ence that the C-terminal tail of PC2 is also cleaved in ELVs.

188 We found that full-length APP is cleaved in EVs incubated in the absence of cells.

189 After SREBP2 is cleaved in Golgi, its CTD remains bound to Scap and retu

190 When PCBP2 is cleaved in its linker region by viral proteinase 3CD, tr

191 re, whereby the (001) SrO-terminated surface cleaved in rock-salt layer facilitates a barrier-free wa

192 que rupture and identify substrates that are cleaved in ruptured plaques.

193 We found that mesotrypsin cleaved in the autolysis loop by CTRC exhibited catalyti

194 stereotopic C-CH(2) bonds of cyclopropane is cleaved in the second step of the process.

195 We determined the KZ counterpart to be cleaved in vitro by its prohead protease, an event that

196 2-LTR palindrome junction can be efficiently cleaved in vitro by recombinant integrases, leading to t

197 s, the spike protein is post-translationally cleaved, in this case by furin, into the S1 and S2 compo

198 ng nuclease, whereby bound cA(4) is stepwise cleaved initially to ApApApA>p and subsequently to ApA>p

199 Interestingly, the SORLA ectodomain is cleaved into a soluble form, sSORLA, which has been show

200 ic biosensing peptide on the surface that is cleaved into a urinary reporter upon exposure to specifi

201 Slit proteins are endogenously cleaved into a variety of N- and C-terminal fragments, a

202 INF2 is cleaved into an N-terminal DID-containing fragment and a

203 The dimer is cleaved into its parent radicals when exposed to ultravi

204 The full-length Slit (Slit-FL) is cleaved into Slit-N and Slit-C fragments, which have pot

205 turation in which the viral polyproteins are cleaved into smaller components.

206 is predicted to be a lipoprotein and that is cleaved into two discrete fragments by a clostripain-lik

207 HIV-1 Env precursor (gp160) is cleaved into two units noncovalently bound to form a tri

208 uction of complex concatemeric DNA, which is cleaved into unit length viral DNA for packaging into th

209 ated PD-L1 transcription in part through its cleaved intracytoplasmic domain (ICD), which bound to a

210 (GLDH), total cytokeratin 18 (K18), caspase cleaved K18, glutathione S-transferase alpha, alpha-feto

211 Importantly, CTRC-cleaved mesotrypsin degraded SPINK1 with markedly reduce

212 refolding and reformation of the previously cleaved metal-ligand bonds, effectively repairing the in

213 NA decay, avoiding the buildup of toxic endo-cleaved mRNA decay intermediates.

214 gh-throughput technique developed to capture cleaved mRNA fragments and thus can be used to support m

215 Sequencing cleaved mRNAs validated 42 conserved miRNAs with 83 targ

216 Strikingly, when titin-cleaved muscles contract, myosin-containing A-bands beco

217 ondary cleavage of GSDMD to an alternatively cleaved N-GSDMD product.

218 rosomal membranes and found that Astn2 has a cleaved N-terminal signal peptide, an N-terminal domain

219 tant cells induces an exclusive reduction in cleaved NOTCH1 expression.

220 Cleaved NOTCH1, HES1 (Hes family BHLH transcription fact

221 2) )](2+) core relative to its isomer with a cleaved O-O bond having a [Cu(III) (2) (mu-O)(2) ](2+) u

222 lysosome where their cholesterol esters are cleaved off by acid lipase.

223 ins have N-terminal leader peptides that are cleaved off by the cysteine protease domain, referred to

224 to mitochondria, these targeting signals are cleaved off by the mitochondrial processing peptidase (M

225 The O(2) molecules are cleaved on discharge, reforming O(2-), but the manganese

226 ever, most implementations are based on flat-cleaved optical fibers that can only interface with shal

227 nt chemical bonds that can also be reversed, cleaved or exchanged are the subject of so-called dynami

228 ecreted ORF2g (glycosylated ORF2) and ORF2c (cleaved ORF2) forms that are not associated with infecti

229 nhibitor of ferroptosis, with an increase in cleaved PARP and caspase-3.

230 oteins that induce apoptosis, including BIM, cleaved PARP, and cleaved caspase 3.

231 siRNA loading into Argonaute, degradation of cleaved passenger strand and degradation of sliced targe

232 > 2 MDa in size and that N-terminal GPS/GAIN cleaved PC1 and PPC cleaved fibrocystin ectodomains can

233 It cleaved penicillin and was inhibited by sulbactam.

234 ability to distinguish between an intact and cleaved peptide was investigated in detail using LL37(FR

235 MHC-I peptides are intracellular-cleaved peptides, usually 8-11 amino acids in length, wh

236 Thrombin cleaved pro-IL-1alpha at a site perfectly conserved acro

237 t in quiescent cells DBC1 is proteolytically cleaved, producing a protein (DN-DBC1) that misses the S

238 It shows that the C-terminal cleaved product of apple RIN4 (MdRIN4) but not AtRIN4 is

239 We show that DeltaN-JARID2 is a cleaved product of full-length JARID2 spanning the C-ter

240 -80% difference in response, compared to the cleaved product, was observed.

241 y stabilizing the folded ground state or the cleaved product.

242 , while uncleaved proheads without portal or cleaved proheads with portal did not bind.

243 chwannomas, leading us to identify a caspase-cleaved, proteasome-resistant NIK kinase domain fragment

244 developed plaques highly enriched in ADAM10-cleaved PrP and heparan sulfate (HS).

245 IdeS quickly cleaved purified 5B9, a monoclonal chimeric anti-PF4/H I

246 Serum levels of total soluble RAGE and cleaved RAGE (cRAGE) were significantly lower in periodo

247 , bovine IgG2 and human IgG1 antibodies were cleaved rapidly into Fab and smaller fragments, pointing

248 It also cleaved reduced laminaripentaose and transferred oligosa

249 As Robo, the cleaved region of Robo, and SYG-1/Neph are all highly co

250 e azo group in Cy-Azo is reduced by AzoR and cleaved resulting in the production of Cy-NH(2)) was pro

251 nder gamma-radiation, the hydrogen bonds are cleaved, resulting in the release of pemetrexed.

252 we show that the destabilization of AvrRpt2-cleaved RIN4 fragments is independent of the N-end rule

253 ically active, whereas all Type 2 conjugates cleaved RNA target in a sequence-specific manner, with u

254 se a role during viral infection for RNase L-cleaved RNAs in inducing avSGs containing antiviral prot

255 The identity of the cleaved S-C bond correlates with SAM ribose conformation

256 ne area can be explained by the formation of cleaved secondary products.

257 The cleaved sites are subsequently ligated with adaptors for

258 ngstrom, including an apo state, a caspase-7-cleaved state and a carbenoxolone-bound state.

259 The postcatalytic state captures the cleaved substrate bound to the catalytically competent H

260 CGEP specifically cleaved substrates on the C-terminal side of Glu irrespe

261 hat neuropilin-1 (NRP1), known to bind furin-cleaved substrates, significantly potentiates SARS-CoV-2

262 enabled us to determine the structure of the cleaved synaptic complex intasome, which is the direct t

263 Cleaved target sites are then selectively PCR amplified.

264 alytic state, the HNH catalytic state, and a cleaved-target-DNA-bound state.

265 The use of readily cleaved tert-butoxycarbonyl (Boc) or carboxybenzyl (Cbz)

266 gamma-(AB)-d4TTPs are faster cleaved than gamma-(ACB)-d4TTPs.

267 r activation by tissue plasminogen activator cleaved the bound histone.

268 Accordingly, NleD cleaved the flexible loops of JNK and p38 but not the ri

269 We found that Mt2 specifically cleaved the key components of the hepcidin-induction pat

270 reover, we showed that FEN1 also efficiently cleaved the RNA strand, facilitating pol beta loop/hairp

271 yme pyruvate formate-lyase activating enzyme cleaved the S-C5' bond to generate a 5'-deoxyadenosyl ra

272 This enzyme cleaved the tripeptide aldehyde protease inhibitors, lea

273 (Env), which consists of trimeric (gp160)(3) cleaved to (gp120 and gp41)(3), interacts with the prima

274 elope glycoprotein [Env; trimeric (gp160)(3) cleaved to (gp120/gp41)(3)] attaches the virion to a sus

275 full-length precursors and are subsequently cleaved to distinct fragments.

276 he primary component of AVX-470, were slowly cleaved to F(ab')(2) fragments.

277 The Si-H bond is heterolytically cleaved to form a tungsten(II) hydride and a silylium io

278 We isolated Env (fully cleaved to gp120 and gp41) from the surface of expressin

279 sialidase in the reaction, the substrate is cleaved to release luciferin, which is subsequently oxid

280 cifically, RARRES1, which is proteolytically cleaved to release the extracellular domain, was endocyt

281 ailed insight on how pIgR can be potentially cleaved to release the SC.

282 Isethionate is then cleaved to sulfite and acetaldehyde by a previously unch

283 hydroxyethyl) terephthalate (MHET), which is cleaved to terephthalic acid and ethylene glycol by MHET

284 ed by generating soluble and proteolytically cleaved trimers of gp140 Env that are stabilized by a di

285 hout the SOS and IP changes, proteolytically cleaved trimers tend to disintegrate into their constitu

286 mbinant mouse enzymes demonstrated that CTRL cleaved trypsinogens and suppressed trypsin activation.

287 of its N-acetyl functionality, which can be cleaved under mild conditions using the enzyme family of

288 yclohexenyl ketone products could readily be cleaved under mildly acidic conditions to access a range

289 that the two exolytic alginate lyases mainly cleaved unsaturated guluronic acid oligosaccharides to m

290 droxylamines bearing desthiobiotins that are cleaved upon amide formation, we demonstrate that tracel

291 rate-limiting step in the formation of fully cleaved Va.

292 Hepatic MMP-9 proteolytically cleaved VEGF after partial hepatectomy.

293 These were then cleaved via a Ni-catalyzed esterification reaction with

294 t was activated normally by human VWF D4 and cleaved VWF multimers, preferentially under fluid shear

295 stability and can be rapidly and completely cleaved with functionalized alkyl-, aryl-, and H-tetrazi

296 Both linkers are quantitatively cleaved within minutes under NaIO(4) treatment.

297 Under acidified conditions, Lgmn cleaved within the extracellular N terminus of PAR(2) at

298 resistant to proteolysis, but can be slowly cleaved within the protease-binding loop by target prote

299 single RNA stem; this stem forms only in the cleaved xbp-1 ncRNA fragment.

300 t ligated but 2'-phosphorylated HAC1 mRNA is cleaved, yielding a decay intermediate with both 5'- and