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1 cin (Van), Linezolid (Lin), and Clindamycin (Clin).
2 inducible and constitutive CliNS, 14.6% were CliNS.
3 g sections dominate the New versus Old World clines.
4 nal, or linkage effects in the remaining two clines.
5 ffects occurred in most, but not all, of the clines.
6 tions positioned at either end of the native clines.
7 s and pigmentation rarely showed elevational clines.
8 warm and cold sites, potentially maintaining clines.
9 435 individuals, demonstrating three genetic clines.
10 nce of contrasting locally adaptive regional clines.
11 ussing instances where patterns differ among clines.
12 size (T-S) responses and latitude-size (L-S) clines.
13 s and targets of selection among the sampled clines.
14 raphy and selection, could contribute to the clines.
15 ecting key diapause traits, forming adaptive clines.
16 ne region can explain many of the amino acid clines.
18 reased with one of the two clinical strains (Clin 1, P=0.0006) and decreased by AD-169 (P=0.0016).
23 in Europe, and displays parallel latitudinal clines across continents, providing strong indirect supp
26 ens, Bombus pensylvanicus) exhibit body size clines across the urban gradient, despite a lack of popu
27 ive isolation by comparing site-wise genomic clines against global patterns and identified a breakdow
29 rge movement of prestin, linear capacitance (Clin) also displays voltage dependence as motors move be
30 differences and evolution across geographic clines among continents of the intertidal grass Spartina
32 arriers to gene flow along parallel salinity clines and coincides with a physiologically stressful sa
33 ClineHelpR R-package for visualizing genomic clines and detecting outlier loci using output generated
34 dence from natural populations of geographic clines and seasonal cycling, and stable heterotic polymo
35 ore variable and exhibit steeper latitudinal clines and stronger relationships with local environment
36 They are characterized by rapid temperature clines and varied flow disturbance regimes, both of whic
37 t differences parallel latitudinal body size clines, and will influence predicted impacts of climate
38 ears), diapause variation in the latitudinal clines appears to have aided North American flies in ada
39 range, but it is unclear whether elevational clines are consistent among different mountain ranges.
40 evious investigation suggests that many such clines are due to spatially varying selection rather tha
41 tasets documenting changes to gene frequency clines are extremely rare but provide a powerful means o
42 the conditions under which allele frequency clines are more or less likely to evolve as multiple qua
44 nterpret and consequently visualize 'genomic clines' are limited, and users must often write custom,
45 rimental approaches, such as sampling across clines, artificial evolution experiments, and resurrecti
47 oci displaying host differences, latitudinal clines, associations with adult eclosion time, and withi
48 lycogen synthesis, parallel the low activity clines at G6PD for reduced pentose shunt flux in norther
52 ication resulted in even steeper latitudinal clines by selecting aliens distantly related to natives
53 tory and physiology vary along environmental clines can reveal functional insight into adaptations to
55 clinical nanopore Cas9-targeted sequencing (Clin-CATS) for parallel in-depth repeat analysis, we eva
56 onment associations, and spatial and genomic clines demonstrate that two unrecognized species are pre
57 lts provide evidence that recurrent adaptive clines do not necessarily reflect shared adaptive proces
60 (Tugal-Tutkun and Urgancioglu, Graefes Arch Clin Exp Ophthalmol 244:742-6, 2006; Tugal-Tutkun et al.
61 dy in Drosophila melanogaster of latitudinal clines for 23 SNPs embedded in 13 genes (Pgi, Gapdh1, UG
62 The existence of temporally stable frequency clines for In(2L)t in natural populations of Drosophila
63 which may explain the absence of latitudinal clines for PGM allozyme alleles, the lack of association
65 clades, we find oxygen-dependent altitudinal clines for steady-state levels of protochlorophyllide, e
66 Remarkably, in both species, the geographic clines for the major wing-pattern loci are displaced by
67 to calculate null expectations for body size clines from a thermal perspective, aiding mechanistic in
68 s showed broadly coinciding, steep frequency clines from north to south across this zone beside the f
73 changed, we see five genes where latitudinal clines have been lost or gained and two where the slope
76 damage), and climate-associated cyanogenesis clines have evolved throughout the native and introduced
78 s published in 2012 (Senti et al., J Allergy Clin Immunol, vol 129(5):1290-1296), the current study i
84 highlight the role of host hybridization and clines in altering host-pathogen interactions, dynamics
86 dies utilizing whole-genome data to identify clines in D. melanogaster and several other systems.
87 dients were associated with the evolution of clines in defense in 47% of cities throughout the world.
93 ostglacial range expansions have resulted in clines in genetic diversity across present-day distribut
97 3 North American cities to test for parallel clines in melanism, a genetically based trait associated
98 d, Hex-C), presents a picture of latitudinal clines in metabolic genes prevalent around the branch po
102 olymorphisms showing significant latitudinal clines in North America, the derived allele is the one i
106 etween geographic locations and across depth clines in the Caribbean coral, Montastraea cavernosa.
107 extended functionality can evaluate genomic clines in the context of spatial and environmental featu
108 inversions on the third chromosome, and the clines in the inversion frequencies across the southwest
109 S. alterniflora has evolved different trait clines in the native and introduced ranges, showing the
110 phenotype, and allele frequency-environment clines in the native range predict those in the invaded
111 Marked differences were apparent between the clines in the occurrence and magnitude of the significan
113 logical processes associated with these wide clines include cell signaling, olfaction, and pheromone
114 gical processes associated with these narrow clines include physiological and immune responses to the
119 Notably, these wasps exhibited chromosomal clines, involving chromosome number and decreasing of GC
120 sm collections across north-south geographic clines is useful in the detection of marker associations
123 ough analytical predictions for the width of clines maintained by heterozygote disadvantage fit well
124 eviously reported Est-6 allozyme latitudinal clines may be accounted for by the interaction between s
130 also correspond to genetic and morphological clines observed across a range of marine organisms.
132 s the world, we reveal ubiquitous and strong clines of decreasing colour lightness towards colder reg
134 ross 3.4 million individuals from four major clines of global ancestry (approximately 21% non-Europea
135 s and exogenous viability selection generate clines of similar shape, but the comparison has not been
137 with analyses of changes in neutral genetic clines offers a powerful way to obtain ecologically rele
138 f multi-locus differentiation (i.e., genomic clines) often extend broadly across hybrid zones and the
141 sults suggest that recapitulation of genetic clines over latitude and altitude involves extensive par
142 imate and that temperature and precipitation clines predict the invasive performance of particular pr
144 uman skin pigmentation is the product of two clines produced by natural selection to adjust levels of
147 ible (EryNS) and clindamycin-nonsusceptible (CliNS) strains to those with susceptible infections.
148 are structured into three distinct admixture clines stretching between various western and eastern Eu
150 In addition, results from basin-wide genomic clines suggested that hybrids and parental forms are ada
151 with BEAST analysis identified two separate clines, suggesting that TBEV spread both east and west f
152 The diversity in genetic architecture of the clines suggests that natural selection has produced simi
153 transgenic cell class-lineage intersection (CLIn) system to assign cells of a particular class to sp
155 ermore, some sublineages demonstrate genomic clines that recapitulate cladogenetic events, suggesting
157 For both females and males of all three clines, the generation means were adequately described b
159 locus basis and examined the distribution of clines to detect those that exhibited signifcantly steep
160 northern and southern ends of each of these clines to produce F(1), F(2), and first backcross genera
161 tosomal markers exhibit asymmetrically broad clines, usually with high frequencies of M. domesticus a
162 a normal (gnomAD) and other databases (LOVD, Clin Var and 100,000 Genomes Project) to determine their
163 s revealed that the evolution of urban-rural clines was best explained by adaptive evolution, but the
169 ce of both isolation by distance and ancient clines, whereas there was no evidence of structure in SE
170 effects as a byproduct of its assessment of Clin, which increases during salicylate treatment as mot
171 nce) traits exhibited geographic or climatic clines, which often remained significant after accountin
172 rary patterns of adaptation to environmental clines will mediate future plant responses to projected
174 lection will form monotonic allele frequency clines with their selective environment, which has led t
175 e width of the chromosomal and mitochondrial clines, with cline centres displaced at least 2.5 km.