ライフサイエンスコーパス: clinical course

1 erstood, and it may vary by presentation and clinical course.

2 are genetically predisposed to an aggressive clinical course.

3 es that are characterised by a heterogeneous clinical course.

4 transmitted infection with a highly variable clinical course.

5 l lymph nodes, most cases have an uneventful clinical course.

6 ts were the youngest and had the most severe clinical course.

7 itting inflammatory disorder with a variable clinical course.

8 generally favorable outcomes but a variable clinical course.

9 ith atypical radiology and a more aggressive clinical course.

10 ors for poor outcomes, had a relatively mild clinical course.

11 uld guide novel interventions to improve its clinical course.

12 ontrast to a previously stable, asymptomatic clinical course.

13 ents through the entire disease spectrum and clinical course.

14 end point that evaluated the initial 48-hour clinical course.

15 ncer treatment, and most had an unremarkable clinical course.

16 LBP are musculoskeletal and benign in their clinical course.

17 al subtype, with later onset and less severe clinical course.

18 T and TT genotype and the severity of the AP clinical course.

19 thin the CSF produced C3 in correlation with clinical course.

20 37.5%, and 2 persons had a severe disabling clinical course.

21 ciated with a heterogeneous presentation and clinical course.

22 ic/myeloproliferative neoplasm with variable clinical course.

23 but have also been deployed to forecast the clinical course.

24 n hospital are at increased risk of a severe clinical course.

25 rvision due to the possibility of the severe clinical course.

26 changes in work productivity and longer-term clinical course.

27 sma cell neoplasm with an extremely variable clinical course.

28 ammatory lesions and shows a more aggressive clinical course.

29 bsequent pars plana vitrectomy for worsening clinical course.

30 for reassessment of PML pathophysiology and clinical course.

31 yperparathyroidism that may help predict its clinical course.

32 f rotating call schedules; and 3) changes in clinical course.

33 is methylation pattern had a more aggressive clinical course.

34 but also triggered reflection on the entire clinical course.

35 rked heterogeneity in treatment response and clinical course.

36 ove our understanding of the disease and its clinical course.

37 s system disease and progressively worsening clinical course.

38 o infection and may experience a more severe clinical course.

39 ction, which precedes an unstable post-natal clinical course.

40 mature T-cell neoplasm with a heterogeneous clinical course.

41 We diagnosed PFAPA syndrome on the basis of clinical courses.

42 to the visit revealing a wide variability of clinical courses.

43 , brain oxygenation), structural injury, and clinical course added less.

44 study is to describe disease recurrence and clinical course after LT.

45 In contrast, the clinical course after transplantation in DWF patients di

46 In contrast, the clinical course after transplantation in DWF patients di

47 Disease duration, clinical course, age, and gender contribute to the dynam

48 timicrobial therapy and exhibits a relapsing clinical course; an effective vaccine is therefore urgen

49 with IVIG, which is related to a more severe clinical course and a poorer outcome.

50 They are characterized by differences in clinical course and by divergent addiction to oncogenic

51 ble at early disease stages to prognosticate clinical course and design future therapeutic trials.

52 D-19 patients on admission was predictive of clinical course and disease severity.

53 l mutations and is characterized by indolent clinical course and favorable outcome.

54 racterized by an initial relapsing-remitting clinical course and focal inflammatory lesions that have

55 ollowed to 90 days after initial imaging for clinical course and for the primary outcome of any inter

56 ene and immunoglobulin locus, has a variable clinical course and frequently undergoes transformation

57 pe A receptor antibodies associated with the clinical course and histopathological findings of intest

58 ecorded motor activity may predict inpatient clinical course and hospital discharge remains unknown.

59 Little is known about the clinical course and imaging features of patients that pr

60 We describe the clinical course and imaging findings of a similar AMN-li

61 homa (MCL) is characterized by an aggressive clinical course and inevitable development of refractory

62 Clinical course and laboratory metrics were compared bet

63 de cholangiopancreatography earlier in their clinical course and maintained long term in vitro as thr

64 We report the clinical course and management of a liver transplant rec

65 HE1 gene transfer dramatically improved both clinical course and metabolic abnormalities.

66 Clinical course and multimodal retinal imaging including

67 ther studies are warranted to understand the clinical course and optimal management of this distinct

68 Clinical course and outcome data were collated prospecti

69 However, the influence of AF on clinical course and outcome in HCM remains incompletely

70 tic DCM, but their exact contribution to the clinical course and outcome is unknown.

71 iomarker of health and inflammation, and the clinical course and outcome of GBS in patients treated w

72 atment of disease progression, prediction of clinical course and outcome, and management of complicat

73 Clinical course and outcomes were similar to those repor

74 different mechanisms lead to differences in clinical course and pattern of accrual of permanent disa

75 d young adults and has a rapidly progressive clinical course and poor outcome due to its refractorine

76 The authors aimed to clarify clinical course and prognosis of a large cohort of HCM p

77 e in peripheral blood eosinophils during the clinical course and received prednisolone for the same,

78 ons, which lead to substantial variations in clinical course and response to therapy.

79 contribute to their relatively more indolent clinical course and responsiveness to therapy.

80 /S) classification of GBM tumors can predict clinical course and sensitivity to drug treatment.

81 We studied the clinical course and sequelae of CGD patients diagnosed b

82 DWF requires better definition of causes and clinical course and then trials of therapies to improve

83 cardiomyopathy) are associated with distinct clinical course and therapeutic approach, although in re

84 Given differences in clinical course and therapy response, we sought to chara

85 n of subgroups is important in understanding clinical course and to anticipate resuscitative and ther

86 his could have implications to predict later clinical course and to select appropriate management app

87 nd included all studies that reported on the clinical course and treatment for foodborne botulism.

88 representing the major phases of the glioma clinical course and were further subgrouped by histology

89 As incongruence between clinical course and WHO grade exists, reliable biomarker

90 iversal markers for predicting a complicated clinical course and/or risk of a poor outcome.

91 vations: In this case series, we explore the clinical courses and genotypes of a woman and her 2 daug

92 cognized osteosarcoma subtypes with distinct clinical courses and response to therapy could be transl

93 ide variants and is associated with distinct clinical courses and response to therapy.

94 egarding the minimum exposure, nature of the clinical course, and additional clinical features needed

95 d, correlated with the subsequent short-term clinical course, and described in a case series.

96 What is changing is our definition(s), its clinical course, and how we manage the septic patient.

97 is limited knowledge about the presentation, clinical course, and immunosuppression management of thi

98 and describe the identification, diagnosis, clinical course, and management of the case, including t

99 may be involved in the pathogenesis of ACLF, clinical course, and mortality.

100 Visual acuity, clinical course, and multimodal imaging study results.

101 F) can blunt the pathophysiology, temper the clinical course, and offer prospects for curative therap

102 reus, heterogeneity of disease presentation, clinical course, and outcome between individual S. aureu

103 Data on the epidemiology, clinical course, and outcomes of critically ill patients

104 wledge of the genetic and molecular origins, clinical course, and outcomes of the most common phenoty

105 med COVID-19, and describe their management, clinical course, and outcomes.

106 ecorded postoperative VA, time to NLP onset, clinical course, and principal cause.

107 ent demographic characteristics, treatments, clinical course, and serologic and genetic markers.

108 he prevalence of newly acquired frailty, its clinical course, and the co-occurrence of frailty with d

109 variable that contributes to the incidence, clinical course, and treatment outcome of brain disorder

110 ss index, ophthalmic examination, treatment, clinical course, and visual outcomes.

111 We compared baseline characteristics, clinical courses, and therapies in children with MRSA co

112 ty of approaches to diagnosis, a spectrum of clinical courses, and unsettled perspectives on therapeu

113 elop skin lesions, but the lesions and their clinical course are not well-characterized.

114 worldwide, we found significant variation in clinical course associated with age at diagnosis, sex, a

115 ase appear to experience a relatively benign clinical course, associated with a low risk for advanced

116 rding to 2010 McDonald criteria, a relapsing clinical course, brain MRI lesions consistent with multi

117 ence of EAE or the trajectory of its initial clinical course, but it limited the extent of chronic CN

118 To describe the phenotype, long-term clinical course, clinical variability, and genotype of p

119 Images and clinical course data of 57 patients who were diagnosed w

120 ct had an early-onset but slowly progressive clinical course dominated by neurological deterioration

121 turbidimetry and related to demographics and clinical course during a follow-up of 6 months.

122 The clinical course during the first years of life can be po

123 The clinical course, electrocardiograms, and Holter monitori

124 he role of the innate immune response in the clinical course following severe injury and envisions a

125 is an incurable disease with a heterogeneous clinical course, for which the treatment decision still

126 2015, to provide individual patient data on clinical course from CCM diagnosis until first CCM treat

127 has been postulated to lead to a more severe clinical course from other structurally related viruses,

128 enesis, surgical concerns, and postoperative clinical course from those of age-related cataracts, and

129 ngitudinal study investigated the frequency, clinical course, genetic profile and health related qual

130 not affect clinical decision-making or alter clinical course (grade 1 and 2) in 37% of cases.

131 Diagnostic workup, clinical course, immunosuppression/antiviral management,

132 eport of the clinical features and long-term clinical course in a family of NTG patients with TBK1 ge

133 The clinical course in affected individuals began with norma

134 brief perspective on the short-term COVID-19 clinical course in an immunosuppressed child.

135 ify homogenous patient subgroups with shared clinical course in critical illness deciphering disease

136 rs for a better prognostic prediction of the clinical course in esophageal adenocarcinoma (EAC) are s

137 ed patient numbers, have also shown that the clinical course in ISM is stable and comparable to that

138 multisystemic symptoms, and early death; the clinical course in MLIII is less progressive.

139 onic expression was associated with a better clinical course in single cases.

140 unique aspects of P. malariae diagnosis and clinical course in travelers.

141 ysfunction and its contribution to divergent clinical courses in CF.

142 Patients with SLI had a more severe clinical course, including higher rates of intensive car

143 , were retrospectively evaluated in terms of clinical course, involved drugs, daily drug dose, latenc

144 The clinical course is characterized by a progressive loss o

145 This unusual clinical course is consistent with a contribution of ant

146 The clinical course is generally aggressive and accounts for

147 to small-cell lung cancer (SCLC), but their clinical course is poorly characterized.

148 l to assess their impact on the longitudinal clinical course (measured by means of Expanded Disabilit

149 We determined the clinical course of 301 consecutive patients with ARVC us

150 The aim of this study was to describe the clinical course of a consecutive series of patients oper

151 Prompted by the clinical course of a renal allograft recipient, who lost

152 78) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).

153 oxicity in the surrounding neuropil over the clinical course of AD, thereby potentially contributing

154 burden remains relatively stable through the clinical course of AD, whether these features of local p

155 the cortico-cerebellar processes tied to the clinical course of ADHD are separated from the subcortic

156 ry, radiologic image, medical treatment, and clinical course of admission/quarantine/readmission data

157 less of symptom change, whereas the variable clinical course of adolescent ADHD is determined by plas

158 To describe the clinical course of advanced juxtapapillary retinal capil

159 ariants in the complement pathway modify the clinical course of AMD and increase the risk of developi

160 re equally superior to AC for describing the clinical course of AP.

161 This study sought to describe the clinical course of ARVC and occurrence of life-threateni

162 The long-term clinical course of asthma phenotypes defined by clusteri

163 and conflicting data regarding the long-term clinical course of atopic dermatitis (AD).

164 We therefore aimed to study the clinical course of atopic diseases and type I sensitizat

165 rospective studies have begun to outline the clinical course of breast implant ALCL.

166 r understanding of the burden AKI has on the clinical course of burn patients would highlight the nee

167 ogenesis and endotypes and prediction of the clinical course of childhood asthma phenotypes.

168 BACKGROUND & AIMS: The clinical course of chronic pancreatitis is unpredictable

169 s, we aimed to investigate the frequency and clinical course of CN.

170 The clinical course of complicated community-acquired pneumo

171 The clinical course of complications was highly variable, fr

172 f exosomes are associated with the onset and clinical course of critical illness.

173 unusual histologic presentation and distinct clinical course of dense deposit disease, discuss the pi

174 gG in STAT3-HIES patients and attenuated the clinical course of disease suggesting a role of humoral

175 rovides a valuable mouse model mirroring the clinical course of disease that can be used to test pote

176 ritoneally with Brucella melitensis, and the clinical course of disease, histopathologic changes, and

177 BcR-BcR interactions apparently dictate the clinical course of disease, with stronger affinities and

178 th Carolina to describe the epidemiology and clinical course of disease.

179 visual acuity, tolerance of miltefosine, and clinical course of disease.

180 to better define the impact, phenotype, and clinical course of DWF in the current era.

181 to better define the impact, phenotype, and clinical course of DWF in the current era.

182 The clinical course of EAE is not improved by the solTNF inh

183 that both cibinetide and EPO ameliorated the clinical course of experimental colitis in mice, resulti

184 ne the incidence rate, principal causes, and clinical course of eyes developing no light perception (

185 gressive lymphoma is a critical event in the clinical course of follicular lymphoma (FL) patients.

186 To determine the epidemiology and clinical course of functional impairment and decline in

187 tations in humans, potentially modifying the clinical course of genetic diseases, remains unknown.

188 To analyze the incidence and clinical course of graft rejection episodes after Descem

189 hypertrophy is an early hallmark during the clinical course of heart failure and is regulated by var

190 Additionally, the milder clinical course of HIV-2-induced disease is apparently n

191 association between Vitamin D levels and the clinical course of HL needs to be collected to advance t

192 and their bioproducts in the development and clinical course of IBD, and strategies by which microbio

193 The clinical course of idiopathic pulmonary fibrosis (IPF) i

194 The clinical course of IgA nephropathy (IgAN) varies from as

195 r myeloid cell compartment had a more severe clinical course of infection and increased parasite burd

196 The clinical course of low back pain is often favourable, th

197 lgorithm has altered management strategy and clinical course of many HCM patients, making the likelih

198 rge animal studies to most closely mimic the clinical course of MI and enable translational success.

199 nd model experimental design to resemble the clinical course of MI.

200 Understanding the epidemiology and clinical course of multisystem inflammatory syndrome in

201 The clinical course of NLPHL is indolent in the majority of

202 Smad7 overexpression worsened the clinical course of OSE and increased CNS inflammation an

203 ess these limitations; it aims to assess the clinical course of patients as a physician would in prac

204 We retrospectively reviewed the clinical course of patients diagnosed with ISCMs at our

205 healthy individuals and also complicates the clinical course of patients requiring intensive care as

206 facilitating decongestion and improving the clinical course of patients with acute heart failure (AH

207 The long-term clinical course of patients with an enterovirus central

208 Our data demonstrate that the clinical course of patients with ATS1 is characterized b

209 RCA2a at the dose tested did not improve the clinical course of patients with heart failure and reduc

210 the biology of reverse LV remodeling and the clinical course of patients with HFrecEF, as well as pro

211 The clinical course of patients with hypertrophic cardiomyop

212 or, more commonly, develops late during the clinical course of patients with longstanding RP.

213 was conducted to elucidate the longitudinal clinical course of patients with LRBA deficiency who do

214 herapeutically [therST]) on the longitudinal clinical course of patients with natalizumab-related pro

215 -cell transplantation (SCT), we compared the clinical course of patients with NPM1(mut) AML eligible

216 is a paucity of literature investigating the clinical course of patients with spinal intramedullary c

217 The majority of available data on the clinical course of patients with ventricular preexcitati

218 hat pathogenic variants adversely affect the clinical course of PD.

219 Findings demonstrate that although the clinical course of PTSD symptoms shows heterogeneous pat

220 The clinical course of PTSD varies between individuals, and

221 The clinical course of relapse-onset multiple sclerosis is h

222 t B cells play a vital role in mediating the clinical course of relapsing multiple sclerosis (MS).

223 The demographics and clinical course of seven patients with subclinical EDS a

224 The clinical course of spontaneous HBsAg seroconversion was

225 The clinical course of the affected parent was associated wi

226 However, the clinical course of the disease is unclear.

227 is presented due to the relapsing-remitting clinical course of the disease that resulted in patient'

228 The clinical course of the disease varies widely and can in

229 xplore the effects of these mutations on the clinical course of the disease.

230 y titre without apparent improvements in the clinical course of the disease.

231 sk factors and (2) immune markers across the clinical course of the disorder, including cytokines; C-

232 their abundance seems to correlate with the clinical course of the infection.

233 therapeutic intervention, did not alter the clinical course of the patient, 3 - information gained h

234 ected include complete information about the clinical course of the patients including treatment sche

235 r, little is known about the epidemiology or clinical course of these problems, including the extent

236 rs that have been shown to be altered during clinical course of these viral infections.

237 The findings suggest that the clinical course of this common childhood onset disorder

238 future applications aimed at predicting the clinical course of TS in individuals over development.

239 cterial intrahost evolution, we examined the clinical courses of 4 subjects with 3-6 recurrent USA300

240 The heterogeneous clinical courses of chronic hepatitis B virus (HBV) infe

241 We hypothesized that clinical courses of EAE may be shaped by differential gu

242 cal record review compared epidemiologic and clinical courses of pertactin-producing and pertactin-de

243 The aim was to determine if clinical course or characteristics of mechanical ventila

244 Little is known about the clinical course or predictive variables.

245 erve as a universal predictor of complicated clinical course or treatment response and, importantly,

246 inct recovery phenotypes on the basis of the clinical course over the first week after AKI manifestat

247 n LMNA are responsible for a more aggressive clinical course owing to a high rate of malignant ventri

248 rgical patients who experience a complicated clinical course owing to sepsis.

249 nd clinical factors were evaluated to assess clinical course, patterns of recurrence, and survival ou

250 er, relatively little is known regarding its clinical course post-LT.

251 he radiation emitted by (210)Po, an atypical clinical course prompted active consideration of poisoni

252 e features that contribute to differences in clinical course remain limited.

253 NUP188 and strikingly similar phenotypes and clinical courses, representing a recognizable genetic sy

254 3 patients after first LT and analyzed their clinical courses retrospectively.

255 identified and their injection histories and clinical courses reviewed.

256 time should reflect response to therapy and clinical course, serial measurement of LVEF is inconsist

257 Clinical course, slit lamp photographs, and AS OCT findi

258 isual acuities and treatments throughout the clinical course, specific dimensions of the macular hole

259 (WGD), which was associated with aggressive clinical course, suggesting WGD is a hallmark of disease

260 of care, with an overall improvement in the clinical course, survival, and quality of life of affect

261 on were significantly more predictive of the clinical course than complete-blood-count parameters.

262 Females have a more severe clinical course than males in terms of several inflammat

263 mutations and PCH and suggests a less severe clinical course than other PCH subtypes.

264 Outpatients with HFrecEF have a different clinical course than patients with HFpEF and HFrEF, with

265 Infants with the ON1 genotype had a milder clinical course than those with NA1 and more risk factor

266 Exposure to (210)Po resulted initially in a clinical course that was indistinguishable from infectio

267 Due to their protracted clinical course, the evolution to advanced hematological

268 However, based on the clinical course, the patient was suspected to have eosin

269 During the clinical course, the predominant findings included diarr

270 challenging surgical procedures and complex clinical courses, the patients benefit from avoidance of

271 ent cancer types, with distinct histologies, clinical courses, therapeutic responses, and genetic dri

272 Most deaths occurred early in the clinical course; therefore, botulism in children should

273 gards to the circumstances that drive a mild clinical course to a severe disease.

274 ise and to examine their natural history and clinical course to create a more robust understanding of

275 relate variations in them to predisposition, clinical course, treatment response, neuroimaging data,

276 ctive manner to report patient presentation, clinical course, treatment, and outcomes in breast impla

277 We present the clinical course, treatment, and prognosis of a case of u

278 nderstand the genetic basis of the disparate clinical courses, tumors were collected from 34 younger

279 The attenuated clinical course was associated with a relative dearth of

280 Because a favourable clinical course was associated with catch-up growth, hei

281 The clinical course was complicated by arterial hypotension,

282 His clinical course was complicated by debilitating neurolog

283 Assessment of the patient's clinical course was defined by the following: an acute e

284 Progressive clinical course was observed in 45%, carotidodynia in 10

285 A dose- and donor-dependent clinical course was observed in hu-BLT mice infected wit

286 fferentiation response gene 88, or TRIF, the clinical course was significantly attenuated compared to

287 Clinical course was summarized, including requirement fo

288 Visual outcomes, causative organisms, and clinical course were also recorded.

289 Changes in access and speed of care and clinical course were determined through 1746 random hous

290 aphics, predisposing factors, pathogens, and clinical courses were compared to our previous study con

291 Cases were defined as infants whose clinical courses were consistent with necrotising entero

292 With the exception of one case, patient clinical courses were not consistent with true invasive

293 tic inaccuracy is more frequent early in the clinical course when signs and symptoms are mild.

294 l successfully complete their posttransplant clinical course, which is crucial for liver transplant (

295 They had a less severe clinical course with greater event-free survival from ma

296 first LT in 2012 were followed through their clinical course with last follow up in 2019.

297 The majority of patients show a protracted clinical course with persistent disease.

298 IFN-gamma autoantibody disease has a chronic clinical course with persistent infections and death.

299 IFN-gamma autoantibody disease had a chronic clinical course with persistent infections and death.

300 s are generally characterized by an indolent clinical course, with a rate of relapse or metastasis be