ライフサイエンスコーパス: clinical evaluation

1 nd CSF test combinations may add accuracy to clinical evaluation.

2 retinal/macular pathology was identified on clinical evaluation.

3 hibitors are currently undergoing widespread clinical evaluation.

4 acked sufficient specificity and potency for clinical evaluation.

5 ide (27, VU0424238), a compound selected for clinical evaluation.

6 precision of 0.85 for a recall of 0.6 in the clinical evaluation.

7 n previously established through traditional clinical evaluation.

8 inical benefit; NaF imaging was not used for clinical evaluation.

9 ate model, was rapidly advanced into phase 1 clinical evaluation.

10 MP production and has entered a path towards clinical evaluation.

11 e outset to inform both candidate design and clinical evaluation.

12 be carefully assessed as part of a thorough clinical evaluation.

13 ed with MIP-1095, a PSMA ligand currently in clinical evaluation.

14 therefore, in developing USP7 inhibitors for clinical evaluation.

15 tiated a median of 6 hours after the initial clinical evaluation.

16 tant colorectal cancers and warrants further clinical evaluation.

17 Ac-L1 is a promising therapeutic for further clinical evaluation.

18 warranted using neuroimaging or conventional clinical evaluation.

19 rapies directed at mesothelin are undergoing clinical evaluation.

20 celles, providing a strong justification for clinical evaluation.

21 s for the development of small molecules for clinical evaluation.

22 lature of dacomitinib and is currently under clinical evaluation.

23 nonsimulated "in vivo" specimens before full clinical evaluation.

24 nd CSF test combinations may add accuracy to clinical evaluation.

25 nt blockade, with immediate implications for clinical evaluation.

26 s for the development of small molecules for clinical evaluation.

27 rational therapies, some of which are under clinical evaluation.

28 a) and approximately 40 currently undergoing clinical evaluation.

29 also appear promising and are progressing in clinical evaluation.

30 e functional effects using MRI combined with clinical evaluation.

31 in late-stage preclinical tests, poised for clinical evaluation.

32 component, paving the way for a larger-scale clinical evaluation.

33 tional therapeutics are in various stages of clinical evaluation.

34 only four parameters easily obtained during clinical evaluation.

35 which can now claim the leading position in clinical evaluation.

36 idates positioned for detailed PK/PD and pre-clinical evaluation.

37 therapies and few candidates presently under clinical evaluation.

38 ograft models and whose properties warranted clinical evaluation.

39 These results support its continued clinical evaluation.

40 l images such as ultrasound is important for clinical evaluation.

41 MS-986166 (14a), which was advanced to human clinical evaluation.

42 s that have or will soon enter translational clinical evaluation.

43 cy have emerged and are currently undergoing clinical evaluation.

44 lymphoma cell death, which warrants further clinical evaluation.

45 tudy underwent annual neuropsychological and clinical evaluations.

46 rdiac arrest outcomes significantly in other clinical evaluations.

47 Patients with clinical evaluation 1 year after EOT were eligible.

48 sh LCI from noninfluenza viral infections on clinical evaluations alone in this population of Banglad

49 Clinic Study of Aging participants who had a clinical evaluation and amyloid positron emission tomogr

50 -b-PEG-b-PLGA sol-gels may safely enable pre-clinical evaluation and clinical translation of poorly w

51 A comprehensive algorithm, based on clinical evaluation and complementary tests, is presente

52 synthetic allergy vaccines that have reached clinical evaluation and discuss how molecular vaccine ap

53 aried cognitive and motor symptoms underwent clinical evaluation and DTI imaging.

54 , and motor impairments) using comprehensive clinical evaluation and extensive neuropsychological ass

55 nd second phase which consists of definitive clinical evaluation and follow-up interventions for chil

56 lopmental delays and subsequently undergoing clinical evaluation and follow-up interventions.

57 ementary information to patients' ophthalmic clinical evaluation and has usefulness as an outcome mea

58 PINK5 mutations were sequenced, and thorough clinical evaluation and histopathologic and immunohistoc

59 tion of sudden cardiac arrest after baseline clinical evaluation and imaging at enrollment (positron

60 s requires a methodical approach with expert clinical evaluation and investigations.

61 Here we describe an approach to the clinical evaluation and management of an individual who

62 I-MIBG theranostics have been applied in the clinical evaluation and management of neuroendocrine tum

63 sposition to MDS, discusses implications for clinical evaluation and management, and explores scienti

64 SS and 45 control subjects were enrolled for clinical evaluation and mass cytometry quantification of

65 heavily pretreated patients warrants further clinical evaluation and might ultimately indicate a clas

66 Despite these gains, incomplete clinical evaluation and misdiagnosis by referring clinic

67 All patients underwent clinical evaluation and MRI with a multi-echo chemical s

68 They underwent a standardized clinical evaluation and provided nasopharyngeal and orop

69 ns that are undiagnosed even after extensive clinical evaluation and testing.

70 Finally, clinical evaluation and tests used in the assessment of

71 nces in anticoagulation have facilitated the clinical evaluation and treatment of patients with DVT.

72 he context of epidemiology, pathophysiology, clinical evaluation and treatment, emphasizing the impor

73 nged periods have the potential to transform clinical evaluation and treatment.

74 In summary, detailed clinical evaluation and WES with functional studies in D

75 taset, which may serve as normative data for clinical evaluations and gait rehabilitative devices.

76 Clinical evaluations and magnetic resonance imaging (MRI

77 nostic systems highlights the limitations of clinical evaluations and research studies that restrict

78 All participants agreed to undergo annual clinical evaluations and to donate their brains after de

79 Q2 heterozygous family members had undergone clinical evaluation, and 17 of 51 (33.3%) met diagnostic

80 Data from 7 subjects were used in the clinical evaluation, and a phantom study using an anatom

81 y approach that incorporates bioinformatics, clinical evaluation, and human genetics can help to addr

82 Follow-up data, including clinical evaluation, and results of esophagogastroduoden

83 Several devices are under preclinical and clinical evaluation, and the early experience with more

84 ycoprotein (Env) trimers are prioritized for clinical evaluation, and there is a need for an improved

85 documented in detailed annual cognitive and clinical evaluations, and Alzheimer disease neuropatholo

86 romising agents that are entering into early clinical evaluation are discussed.

87 esting that (64)Cu-GTSM PET imaging warrants clinical evaluation as a diagnostic tool for AD and poss

88 enoinic acid (UAB30) is currently undergoing clinical evaluation as a novel cancer prevention agent.

89 or of cell division, is currently undergoing clinical evaluation as a target for cancer therapy.

90 Based on genetic and clinical evaluation as well as functional and structural

91 Clinical evaluations as well as exome and panel sequenci

92 Clinical evaluation at follow-up was as follows: 56% of

93 rmation was collected on triggering factors, clinical evaluation at presentation, management, culture

94 Enrolled students underwent baseline clinical evaluations before the school year started and

95 re asthma treatment, but necessitates robust clinical evaluation, biomarker profiling and assessment

96 were assessed through literature review and clinical evaluation by a multidisciplinary consortium of

97 aged 55-90 years, underwent a comprehensive clinical evaluation by a trained occupational therapist

98 ing loss was identified from audiometric and clinical evaluation by a worsened hearing threshold comp

99 t a strong proof of concept on which further clinical evaluation could build.IMPORTANCE Checkpoint in

100 nding specific biomarkers of liver damage in clinical evaluations could increase the pool of availabl

101 Conclusion: In this clinical evaluation, DDG-retro provided performance supe

102 Clinical evaluations documented cognitive function proxi

103 clinically affected trio with HCM underwent clinical evaluation, electrocardiography, echocardiograp

104 en) diagnosed according to multidisciplinary clinical evaluation, electrocardiography, laboratory tes

105 A clinical evaluation enrolled adults with suspected pulmo

106 se The Letrozole (Femara) Versus Anastrozole Clinical Evaluation (FACE) study compared the efficacy a

107 , 2015, and November 1, 2017, and at least 1 clinical evaluation follow-up by November 12, 2018.

108 f PU-H71, an HSP90 inhibitor currently under clinical evaluation, followed by treatment with cold-pla

109 (60% African Americans and women) who had a clinical evaluation for AD, had completed in-home cognit

110 nd who had been followed up with imaging and clinical evaluation for at least 6 months.

111 ombinant expression and characterization for clinical evaluation for nearly a quarter of a century.

112 a promising candidate that warrants further clinical evaluation for prevention of congenital HCMV.

113 odilator or inhaled steroids, or unscheduled clinical evaluation for respiratory symptoms.

114 l-based therapies are under pre-clinical and clinical evaluation for the treatment of ischemic diseas

115 ACE1) inhibitor currently undergoing Phase 3 clinical evaluation for the treatment of mild to moderat

116 arge fever (RR, 1.00 [CI, 0.76 to 1.31]), or clinical evaluations for infection (RR, 1.06 [CI, 0.99 t

117 standardized methodology, the Comprehensive Clinical Evaluation Form (CCEF), to describe and charact

118 In a radiographic and clinical evaluation, four relevant distances were evalua

119 Results: NHANES included completed clinical evaluations from mobile examination centers on

120 For subjects with uninformative clinical evaluations, germline DNA samples were (re)sequ

121 omising therapeutic options is available for clinical evaluation; however, the numbers of patients wi

122 ell tolerated in humans and is available for clinical evaluation.IMPORTANCE EBOV hemorrhagic fever is

123 RSV vaccine candidate suitable for pediatric clinical evaluation.IMPORTANCE RSV and HPIV3 are the fir

124 e compared before surgery and at most recent clinical evaluation in 39 consecutive patients with obst

125 The yield of combined molecular autopsy and clinical evaluation in 82 surviving families was evaluat

126 Ivosidenib is under clinical evaluation in a phase 1 study that aims to asse

127 ertussis vaccine BPZE1, currently undergoing clinical evaluation in human phase 2 trials.

128 in animal models and is currently undergoing clinical evaluation in humans.

129 erate (surrogate) mouse or rat bsAbs for pre-clinical evaluation in immuno-competent rodents.

130 ith pan-PI3K/mTOR inhibition currently under clinical evaluation in IPF.

131 statin with this profile, has not undergone clinical evaluation in oncology.

132 -dependent ABC DLBCL lines, supporting their clinical evaluation in patients with ABC DLBCL.

133 ranostic targets should be taken for further clinical evaluation in PDA.

134 oherence tomography improves the accuracy of clinical evaluation in retinoblastoma management.

135 Combining molecular autopsy with clinical evaluation in surviving families increased diag

136 ft model, establish 10a as worthy of further clinical evaluation in the advanced GISTs.

137 growth of BPDCN xenografts, supporting their clinical evaluation in this recalcitrant malignancy.

138 of faulty genes; several RNAi are undergoing clinical evaluation in various diseases.

139 nhibitors of the MET kinase are currently in clinical evaluation, in particular for NSCLC, liver, and

140 Clinical evaluation included motor and cognitive testing

141 In-person clinical evaluations included standardized evaluations f

142 Each patient underwent a complete clinical evaluation including a comprehensive battery of

143 oms possibly related to CMA were invited for clinical evaluation including cows' milk-specific IgE an

144 pectrometry; patients with amyloid underwent clinical evaluation including genotyping and (99m)TC-3,3

145 mple of 10- to 14-year-old adolescents using clinical evaluation including OFC to confirm the diagnos

146 ntly included in several vaccines undergoing clinical evaluation including those for tuberculosis, le

147 Patients underwent clinical evaluations including neurological rating scale

148 nical in vivo testing (if required) and then clinical evaluation, including a comparative pharmacokin

149 Patients underwent a multidisciplinary clinical evaluation, including clinical demographics, ge

150 All patients received a standard clinical evaluation, including collection of history, an

151 coronary artery disease (n=1946) underwent a clinical evaluation, including filling in an LTPA questi

152 Longitudinal clinical evaluation, including full ophthalmic examinati

153 ticipants were assessed with a comprehensive clinical evaluation investigating sensory and motor defi

154 on consequence of severe brain injuries, and clinical evaluation is critical to provide a correct dia

155 ing navigated with compounds currently under clinical evaluation is followed by a discussion of the n

156 Further clinical evaluation is required to determine whether nut

157 disease is primarily cutaneous, and further clinical evaluation is therefore rarely pursued.

158 anticancer drugs and further preclinical and clinical evaluation is warranted.

159 nosis and determination of the cause rely on clinical evaluation, laboratory tests, and imaging studi

160 , or low pretest probability of CDI based on clinical evaluation, laboratory, and imaging results.

161 ational cohort study, DCM patients underwent clinical evaluation, late gadolinium enhancement cardiov

162 1999 and July 2012 were followed until last clinical evaluation, liver transplantation, or death.

163 nce, and the diagnostic gold standard is the clinical evaluation made by a movement disorders expert.

164 e properties of the cancer secretome, as its clinical evaluation may change the therapeutic landscape

165 w application of this information in routine clinical evaluations may transform the future practice o

166 e children were followed longitudinally with clinical evaluation, milk-specific IgE levels, and milk

167 Clinical evaluation, multimodal retinal imaging, genetic

168 ent) were randomized to standard once-weekly clinical evaluation (n = 157) or mandatory twice-weekly

169 By increasing the clarity around the clinical evaluation needs for tests that have the potent

170 Among 117 patients with uninformative clinical evaluations, next-generation sequence analysis

171 This is the first clinical evaluation of a large panel of TCGA-reported ge

172 onclusion: Our analyses, based on a detailed clinical evaluation of a large representative cohort of

173 These changes cannot be assessed during the clinical evaluation of a living patient.

174 We performed a clinical evaluation of a multiplex PCR panel, the enteri

175 y, informing the decision to proceed or stop clinical evaluation of a targeted treatment within a mol

176 Together, these results support further clinical evaluation of AB002 as a potentially safe and e

177 ur results offer a mechanistic rationale for clinical evaluation of ATM inhibitors in PTEN-deficient

178 n together, our results strongly support the clinical evaluation of BAY 1187982 in cancer patients an

179 Clinical evaluation of BTK inhibitors in AML seems warra

180 nventional chemotherapies and prompt further clinical evaluation of CDK inhibitors in AML patients ha

181 Our findings provide a rationale for the clinical evaluation of CFI-402257 in patients with solid

182 imaging assessment could change the current clinical evaluation of choroidal nevi.

183 Early-phase clinical evaluation of CMP-001 and anti-PD-1 combination

184 The clinical evaluation of convalescent plasma (CP) for the

185 present recommendations for preclinical and clinical evaluation of COVID-19 vaccine candidates as we

186 Our results provide support for the clinical evaluation of dasatinib treatment in a selected

187 our data provide a preclinical basis for the clinical evaluation of E6201 in AML patients harboring F

188 have implications for our understanding and clinical evaluation of EAC.

189 These results will set the stage for future clinical evaluation of ELQ and atovaquone combination th

190 ecular and preclinical evidence to support a clinical evaluation of EPA combined with EPHA2 inhibitio

191 The MSA is appropriate for the clinical evaluation of EVD treatments.

192 ients of the randomized EXAMINATION study (A Clinical Evaluation of Everolimus Eluting Coronary Stent

193 Recent clinical evaluation of everolimus for seizure reduction

194 Our results support the clinical evaluation of FTC/TAF for PrEP in women.

195 ional examples provided here demonstrate how clinical evaluation of genomic alterations have refined

196 ith high accuracy and could be useful in the clinical evaluation of glaucoma.

197 ed on April 27, 2007, to enable longitudinal clinical evaluation of health outcomes of survivors of c

198 continued surveillance is important for the clinical evaluation of immunoprophylactic products.

199 g targets and tissue proteotypes can improve clinical evaluation of immunotherapies for NSCLC.

200 Retrospective clinical evaluation of individuals referred to our insti

201 f-infected erythrocytes as a model for early-clinical evaluation of interventions that aim to interru

202 administered at ages 1, 2, and 3 years, the Clinical Evaluation of Language Fundamentals-Preschool,

203 rodynamic studies are a key component of the clinical evaluation of lower urinary tract dysfunction a

204 Design: Annual follow-up of the CE-MARC (Clinical Evaluation of MAgnetic Resonance imaging in Cor

205 isease was retrospectively selected from the Clinical Evaluation of Magnetic Resonance Imaging in Cor

206 gine deprivation and present a rationale for clinical evaluation of MAPK inhibitors in combination wi

207 The findings support the ongoing clinical evaluation of maternal GBS6 vaccination as a po

208 tion, 100 negative adenosine images from the Clinical Evaluation of MR Imaging in Coronary Heart Dise

209 Here, we report results from a clinical evaluation of MV-NIS in patients with taxol- an

210 The development and ongoing clinical evaluation of novel agents targeting a range of

211 in myeloma and provide the rationale for the clinical evaluation of PAK4 modulator in myeloma.

212 A checklist is provided for the clinical evaluation of patients with suspected usual int

213 The Clinical Evaluation of Pertuzumab and Trastuzumab (CLEOP

214 Our findings warrant clinical evaluation of PIM kinase inhibitors in patients

215 These data provide compelling evidence for clinical evaluation of pravastatin as adjunctive, host-d

216 In this first clinical evaluation of programmed cell death protein-1/p

217 We then performed a long-term clinical evaluation of ranolazine in LQT3 patients carry

218 y in NPM1 mutant AMLs, and warrant a broader clinical evaluation of regimen comprising a RA/arsenic c

219 graphy (OCTA) has provided novel insights in clinical evaluation of retinal diseases.

220 A practical and objective method for the clinical evaluation of SFN is needed to improve the mana

221 tomographic (CT) angiography as part of the clinical evaluation of stable chest pain.

222 y and maturation, indicating that additional clinical evaluation of statin therapy in patients on dia

223 cs can provide important information for the clinical evaluation of subtalar joint function; the anal

224 autopsy) in cases of SADS and comprehensive clinical evaluation of surviving relatives.

225 Therefore, the system may enhance the clinical evaluation of TCFA, as well as expand our under

226 These findings are a step toward clinical evaluation of the anti-IL-11 therapy for tuberc

227 These findings support the clinical evaluation of the combination of LuTate and PAR

228 Careful clinical evaluation of the condyle coupled with appropri

229 Objective clinical evaluation of the correction equations for Gold

230 Clinical evaluation of the grafts showed significant imp

231 l values and their correlations could affect clinical evaluation of the macula in healthy patients an

232 Clinical evaluation of the participants was conducted in

233 a genotype-phenotype correlation useful for clinical evaluation of the pathogenicity of the variants

234 Our findings pave the way for the clinical evaluation of the prosthesis in patients affect

235 We performed a clinical evaluation of the recently FDA-cleared illumige

236 To the best of the authors' knowledge, a clinical evaluation of the safety of these toothbrushes

237 of nine subjects participated in this pilot clinical evaluation of the technology.

238 We completed the first clinical evaluation of the Triplex vaccine in 24 healthy

239 memory responses to HCMV, justifying further clinical evaluation of the vaccine against congenital HC

240 alent BMS platform in the EXAMINATION trial (Clinical Evaluation of the Xience-V Stent in Acute Myoca

241 isease models have been established, and pre-clinical evaluation of therapeutics and vaccines has beg

242 iles will enable accelerated preclinical and clinical evaluation of these drugs for the treatment of

243 he results obtained are promising for future clinical evaluation of these etoposide nanosuspensions.

244 The mutations commonly used in clinical evaluation of these tumors are regionally distr

245 ctal cancer treatment, in support of ongoing clinical evaluation of this agent (LCC1315 NCT02010567).

246 ctal cancer treatment, in support of ongoing clinical evaluation of this agent.

247 ncers, providing a rational basis for future clinical evaluation of this combination therapy.

248 ffects in multiple species precluded further clinical evaluation of this compound.

249 These results justify further clinical evaluation of this vaccine candidate.

250 n to mosquitoes and develop models for early-clinical evaluation of transmission-blocking interventio

251 cancer target but also a novel biomarker for clinical evaluation of treatment efficacy.

252 These observations inform and support clinical evaluation of TTM in melanoma.

253 mmunogen selection and guide preclinical and clinical evaluation of vaccines or immunotherapeutics to

254 naturally occurring alternative splicing for clinical evaluation of variants in disease-causing genes

255 trategies and we highlight challenges facing clinical evaluation of ZIKV vaccine candidates.

256 SARS-CoV-2 in biological media, while blind clinical evaluations of 100 suspected samples furtherly

257 In contrast to informal clinical evaluations of oculomotor dysfunction frequency

258 These methods could be used to automate clinical evaluations of the ACA and improve access to ey

259 those recently reported during the long-term clinical evaluations of the same patients.

260 eviously identified molecular diagnosis from clinical evaluation or a research-based epilepsy gene pa

261 ble, some other technologies are still under clinical evaluation or in the early development phase.

262 proved classification accuracy when added to clinical evaluation, or reported harms.

263 st-tier test and compared it with a standard clinical evaluation performed in parallel.

264 , rationale for changes from prior criteria, clinical evaluation, physiologic features, psychosocial

265 In the context of a comprehensive clinical evaluation process, this tool can support clini

266 acteristics available immediately upon first clinical evaluation related COVID-19 mortality.

267 Clinical evaluation revealed blended PTLS and CMT1A phen

268 Clinical evaluation revealed that the SmartCycler II, co

269 racatinib, an inhibitor currently undergoing clinical evaluation, sensitized chemoresistant cells to

270 longer than would be detectable in standard clinical evaluation settings.

271 The primary clinical evaluation should include a CT of the abdomen a

272 Clinical evaluation showed lacrimal functional unit impa

273 valuation is typically followed by multisite clinical evaluation studies to confirm diagnostic perfor

274 MATERIAL/METHODS: This observational clinical evaluation study included 224 patients who were

275 Standard clinical evaluation suggested a diagnosis in 16% of case

276 These clinical evaluations support specific implantation targe

277 Subjects underwent a clinical evaluation that included assessment of DE sympt

278 AML LSC targeting and to consider methods of clinical evaluation that will be most effective for iden

279 atients (58 males, 61 +/- 9 years) underwent clinical evaluation, the Psychometric Hepatic Encephalop

280 t one oncogenic RAS mutant (G12C) undergoing clinical evaluation, there have been substantial advance

281 histone deacetylase class I, is currently in clinical evaluation to overcome resistance to immunother

282 k patients and direct mandatory twice-weekly clinical evaluation to reduce acute care visits during t

283 the peripheral nervous system may help guide clinical evaluations to improve personalized care in lim

284 In previous clinical evaluations, tRES and HESP individually were in

285 nts in Diabetes With Established Nephropathy Clinical Evaluation) trial in patients with T2DM, urinar

286 We performed an initial clinical evaluation using serum from 10 people diagnosed

287 Clinical evaluation was conducted by the operating physi

288 Clinical evaluation was performed by using the Constant

289 A clinical evaluation was performed in which the ability t

290 A full clinical evaluation was performed on all mutation carrie

291 Clinical evaluation was performed, and gingival crevicul

292 A complete clinical evaluation was performed, including BCVA, fundu

293 some miRNA therapies are already undergoing clinical evaluation, we stress the importance of integra

294 One- and 5-year clinical evaluations were completed in the United States

295 Sample collections and clinical evaluations were performed before and 3 months

296 underwent a standardised video protocol and clinical evaluation with a validated questionnaire desig

297 We performed clinical evaluation with GERD-HRQoL questionnaire, upper

298 gnosis of parkinsonism is primarily based on clinical evaluation with limited biomarkers.

299 ); 52 consecutive patients with BP underwent clinical evaluation with the Bullous Pemphigoid Disease

300 ine strategies have advanced to the stage of clinical evaluation with unprecedented speed.