ライフサイエンスコーパス: clinical isolate

1 ith sublethal inocula of a hypervirulent XDR clinical isolate.

2 ing ESBL, carbapenem- and colistin-resistant clinical isolates.

3 XDX using 101 contemporary Acinetobacter sp. clinical isolates.

4 ations generated by Streptococcus pneumoniae clinical isolates.

5 clarithromycin-, and rifampicin-resistant Hp clinical isolates.

6 s in the two strains are widely prevalent in clinical isolates.

7 and test the host immune responses to these clinical isolates.

8 cal for evaluations involving mostly routine clinical isolates.

9 thereby inhibiting anti-OmpA MAb binding to clinical isolates.

10 erformed whole-genome sequencing on food and clinical isolates.

11 ed with resistance to three anti-TB drugs in clinical isolates.

12 ing and -inhibitory factors were observed in clinical isolates.

13 ltiple human astrovirus serotypes, including clinical isolates.

14 d antimicrobial resistance gene detection in clinical isolates.

15 against a panel of genetically distinct HCMV clinical isolates.

16 reservoirs lyse a diverse array of MDR ST131 clinical isolates.

17 select training classes and performed WGS on clinical isolates.

18 l strains examined, including several Indian clinical isolates.

19 galectin-8, and Siglec-14, to different NTHi clinical isolates.

20 ch repair defect is prevalent in C. glabrata clinical isolates.

21 gainst 107 carbapenem-resistant A. baumannii clinical isolates.

22 dilution susceptibility test results for 100 clinical isolates.

23 ed to contribute to antibiotic resistance in clinical isolates.

24 biquitous in representation within S. aureus clinical isolates.

25 h rate of 10403S to the rate observed in the clinical isolates.

26 e with chlamydosporulation efficiency across clinical isolates.

27 tic resistance in laboratory experiments and clinical isolates.

28 reactivity to multiple variant epitopes from clinical isolates.

29 activity of vancomycin against C. difficile clinical isolates.

30 Fecal isolates were compared with clinical isolates.

31 can be found frequently both in vitro and in clinical isolates.

32 In contrast, in a pair of clinical isolates 03-149.1 (polymyxin-susceptible) and 0

33 A total of 540 clinical isolates, 11,035 patient surveillance specimens

34 Results were confirmed with 2 additional RSV clinical isolates, 12/11-19 and 12/12-6, with known huma

35 9 non-CP isolates) as well as 45 prospective clinical isolates (15 CP-CRE and 30 non-CP-CRE) obtained

36 Here we genome sequenced 200 clinical isolates (2010-2016) and analyzed them with 701

37 nel hospitals in 36 countries submitted 2703 clinical isolates (2301 [85%] K pneumoniae and 402 (15%)

38 e isolates tested included 121 retrospective clinical isolates, 45 prospective clinical isolates, and

39 Of the 649 E. coli clinical isolates, 5 (0.8%) consistently produced nonsus

40 Thirty-eight reference strains and 145 clinical isolates (58 MAC and 87 M. abscessus isolates),

41 tes resembled contemporaneous and historical clinical isolates according to all studied traits.

42 n the 7C HT of M. tuberculosis glpK occur in clinical isolates, accumulate in M. tuberculosis-infecte

43 ding of how naturally occurring variation in clinical isolates affects transmissibility, pathogenesis

44 The clinical isolate also had increased survival in blood an

45 re associated with delayed clearance in some clinical isolates, although other mechanisms are likely

46 ils, wortmannin inhibited killing of a rough clinical isolate and not a smooth isolate, suggesting th

47 fication and confirmation of C. auris in 413 clinical isolates and 931 patient surveillance isolates

48 t lines, as well as P. falciparum Senegalese clinical isolates and a short-term-culture-adapted strai

49 also demonstrated in Acinetobacter baumannii clinical isolates and approximately 50% of clinical isol

50 suppression of resistant outgrowth in Ph(+) clinical isolates and cell lines.

51 tion of each of these factors varies between clinical isolates and corresponds to the capacity of eac

52 est the efficacy of our approach on numerous clinical isolates and demonstrate a 2-d reduction in dia

53 use the model to co-culture 28 Fusobacterium clinical isolates and demonstrate that the model success

54 ibility are available due to the scarcity of clinical isolates and difficulty in performing susceptib

55 er the established conditions for amplifying clinical isolates and generating vaccine candidates.

56 charide epitope that is expressed by >95% of clinical isolates and hastens gonococcal vaginal clearan

57 9 mutants already exist among S. maltophilia clinical isolates and have reduced susceptibility to sid

58 Culture of clinical isolates and identification were performed at t

59 n a CodY-deficient strain in three S. aureus clinical isolates and in S. epidermidis.

60 ated with the emergence of resistance within clinical isolates and include new PBP3 structures along

61 of mixed- Candida species biofilms formed by clinical isolates and laboratory strains in the presence

62 tive element ICEKp1 is present in a third of clinical isolates and more prevalent in invasive disease

63 Clinical isolates and mutant Trichomonas CPI-GC that had

64 vealed features of methylomic variability in clinical isolates and provides a rational basis for hypo

65 This approach can be used to classify clinical isolates and provides a universal framework for

66 tiplicity of infection passaging of both NiV clinical isolates and recombinant NiV in Vero cells gene

67 cessfully detected 31 distinct M. pneumoniae clinical isolates and reference strains, and there was n

68 laboratory P. aeruginosa strain PAO1 and CF clinical isolates and then assessed differences in bacte

69 ges in strain Ps33 of P. aeruginosa, a novel clinical isolate, and assayed the exclusion phenotype ag

70 rospective clinical isolates, 45 prospective clinical isolates, and 6 mcr-1-positive Escherichia coli

71 E. coli, is effective against Gram-negative clinical isolates, and has efficacy in mouse models of G

72 an versus recent U.S. isolates, fecal versus clinical isolates, and human versus canine isolates.

73 rage against a panel of genetically distinct clinical isolates, and protection against viral infectio

74 her validate the diagnostic performance with clinical isolates, and show that cAST can deliver accura

75 sequenced and assembled four M. sympodialis clinical isolates, and showed their value for understand

76 We analysed 1218 P. falciparum clinical isolates, and the results show that this deleti

77 Notably, clinical isolates are often EFG1 hemizygous and thus lic

78 The most recent clinical isolates are resistant to several classes of cl

79 to frequencies of 10(-6) and investigated on clinical isolates as a proof-of-concept study, but requi

80 colistin resistance in A. baumannii complex clinical isolates, as well as other Gram-negative organi

81 bsiella oxytoca, the pathway was enriched in clinical isolates associated with respiratory tract infe

82 t activity against VRE, inhibiting growth of clinical isolates at concentrations as low as 0.5 mug/mL

83 s the generation of native-like trimers from clinical isolates at high yields and homogeneity.

84 against Mycobacterium tuberculosis HN878, a clinical isolate belonging to the W-Beijing family.

85 analyses of four strains, H37Ra, H37Rv, and clinical isolates BND and JAL, to determine the differen

86 Therefore, many clinical isolates, both animal and human, are unable to

87 tains activity against most Escherichia coli clinical isolates, but the growth of E. coli colonies wi

88 same phenomenon was also observed in recent clinical isolates, but to a lesser extent compared to th

89 Thus, the biology and drug sensitivity of RC clinical isolates can be efficiently interrogated using

90 y, we sought to assess the prevalence of sub-clinical isolated cardiac amyloidosis (ICA) at autopsy a

91 ombination therapy against MDR P. aeruginosa clinical isolate CL232 was further evaluated.

92 performed on 649 multidrug-resistant E. coli clinical isolates collected between 2011 and 2015.

93 d sequencing data for 451 patients and their clinical isolates collected in a multinational, observat

94 loy whole-genome sequence (WGS) data from TB clinical isolates collected in KwaZulu-Natal, South Afri

95 demonstrated increased adhesion forces for a clinical isolate compared with the lab strain.

96 Here we show that 3 out of 10 clinical isolates contained an ICE.

97 Accordingly, Staphylococcus aureus clinical isolates differ substantially in their capacity

98 Here we explore how clinical isolates differentially activate the inflammaso

99 We further demonstrate that specific GAS clinical isolates display high affinity for the D-domain

100 and phenotypic profiling of 53 C. difficile clinical isolates established from diarrheal samples fro

101 Envs of different clinical isolates exhibit different sensitivities to ant

102 drug-resistant Stenotrophomonas maltophilia clinical isolate expressing L1.

103 ical microbiology practices for retention of clinical isolates for future use were also determined.

104 COMBAT can predict antibiotic efficacy in clinical isolates for quinolones from drug affinity (R2>

105 ies produced from Mycobacterium tuberculosis clinical isolates for the evaluation.

106 We further show that the clinical isolates frequently protect each other from cli

107 y screen of Burkholderia gladioli BCC0238, a clinical isolate from a cystic fibrosis patient, led to

108 against heterologous CCHFV challenge using a clinical isolate from regions where CCHFV is endemic.

109 The challenge set included 123 P. aeruginosa clinical isolates from 12 countries.

110 We assessed 1133 consecutive unique E. coli clinical isolates from 5 medical centers (2010-2011) for

111 We validate our results on clinical isolates from 50 patients.

112 Clinical isolates from 609 patients were sequenced, and

113 Eighty USA300 MRSA clinical isolates from 74 trainees, 6 (8.1%) of whom had

114 g to characterise Pseudomonas aeruginosa MDR clinical isolates from a hospital in Thailand.

115 ly collected Acinetobacter baumannii complex clinical isolates from a hospital system in Pennsylvania

116 ilution phenotypic susceptibility testing on clinical isolates from a multicenter clinical trial of t

117 IDS-associated cryptococcal meningitis using clinical isolates from a randomized controlled trial of

118 ct was observed in laboratory strains and in clinical isolates from a recent California pertussis epi

119 addition, we sequenced nucleic acids from 9 clinical isolates from Africa deposited in global collec

120 ut to assess species identity of a set of 34 clinical isolates from Aspergillus section Circumdati fr

121 ) and B1 were tested against a collection of clinical isolates from canine, of which only B1 showed p

122 Here, we used HSV-1 clinical isolates from Finland to test the relationship

123 We used HSV-1 clinical isolates from Finland to test the relationship

124 ccine candidates or low-cell culture passage clinical isolates from humans or animals.IMPORTANCE Grou

125 independently in two lineages, and show that clinical isolates from multiple lineages are a single nu

126 ution and population genetic structure of 51 clinical isolates from Northeast Brazil was studied.

127 n overall prediction accuracy of 96% for 212 clinical isolates from patients enrolled in four differe

128 We discovered 6 clinical isolates from patients with aspergillosis origi

129 rom the water systems of 17 hospitals and 42 clinical isolates from patients with confirmed or suspec

130 GS) data set from a collection of 4,795 MTBc clinical isolates from six countries with a high burden

131 parameters were used in the analysis of 150 clinical isolates from ten microbial species, resulting

132 termine whether strains LS741 and LS743, two clinical isolates from the cantaloupe outbreak, differ s

133 ed mechanisms of beta-lactam resistance, 180 clinical isolates from the Mayo Clinic and Mayo Clinic L

134 Clinical isolates from the most recent outbreak in the A

135 ital AST (dAST) determined susceptibility of clinical isolates from urinary tract infections (UTIs) a

136 h laboratory strain M. tuberculosis H37Rv or clinical isolates from various lineages.

137 s (including Gram-negative and Gram-positive clinical isolates) grown on agar media by liquid extract

138 stance, no large-scale, genome-wide study on clinical isolates has been undertaken using whole genome

139 Nine other clinical isolates have at least 90% protein identity to

140 in and knock-out strains and comparison with clinical isolates, here we show that deletion of TbD1 co

141 fter an i.v. infection with a Brazilian ZIKV clinical isolate (HS-2015-BA-01) in rhesus macaques for

142 Molecular fingerprinting of clinical isolates identified 2 clonal strains of M. absc

143 Screening of 600 Victorian clinical isolates identified a set of previously unrepor

144 across whole genome sequence data from 2,855 clinical isolates in 21 malaria-endemic countries, we id

145 Nearly 25% of K. pneumoniae clinical isolates in a US network of LTACHs were CRKP.

146 However, it is still challenging to grow HCV clinical isolates in cell culture.

147 irregularis and the mating type ratio of 17 clinical isolates in China.

148 Despite the rarity of PMCR among clinical isolates in the United States, these methods ar

149 pes, potently neutralizes a diverse panel of clinical isolates in vitro and demonstrates in vivo prot

150 undances of P. aeruginosa transcripts across clinical isolates, in serial samples, and for the purpos

151 ed the assay with a collection of 40 E. coli clinical isolates, including 19 confirmed MCR protein pr

152 ood activity against several M. tuberculosis clinical isolates, including four that are resistant to

153 in against multidrug-resistant Gram-positive clinical isolates, including vancomycin- and linezolid-r

154 Comparisons with clinical isolates indicated that such microbes can persi

155 n IL-1beta and caspase-1 activation, but all clinical isolates induced lower IL-1beta release than H3

156 imal related isolates and a further split of clinical isolates into two sub-clades within clade A.

157 rstood: while most ceftriaxone resistance in clinical isolates is caused by target site mutations in

158 eness of low-passage commensal streptococcal clinical isolates is positively influenced in antagonism

159 fluoroquinolone-resistance in K. pneumoniae clinical isolates is reversed by expression of Gam.

160 Raman spectroscopic data for 31 A. baumannii clinical isolates labeled according to their pulsed-fiel

161 sarA-associated phenotypes in the S. aureus clinical isolates LAC and UAMS-1.

162 es provide insights into the pathogenesis of clinical isolates linked to the 2011 cantaloupe outbreak

163 ages AB2 and AB6, can recognize A. baumannii clinical isolates M3237 and 54149, respectively.

164 monocytogenesis 19115 and E. coli O157:H7), clinical isolates (methicillin-resistant S. aureus (MRSA

165 CTX) and ceftazidime (CAZ) against resistant clinical isolates (MIC reduction, 32-fold).

166 tion discovered within a multidrug resistant clinical isolate modifies the plasticity of the transpor

167 his electrochemical detection strategy using clinical isolates obtained from patients with hospital-a

168 ed the phenotypic susceptibility of 12 HIV-2 clinical isolates, obtained from 2 antiretroviral-naive

169 es of either the laboratory Neff strain or a clinical isolate of A. castellaniiIn vitro real-time ima

170 However, macrophages cocultured with the clinical isolate of Acanthamoeba produced significantly

171 s infections, ferrets were challenged with a clinical isolate of BDBV.

172 tection in a BSL-3 model with an aerosolized clinical isolate of Burkholderia pseudomallei from Thail

173 Both a laboratory strain and a clinical isolate of C. albicans were used for SCFS exper

174 nd differentiated cells were infected with a clinical isolate of C. trachomatis, and inclusions conta

175 I interferon-deficient mice infected with a clinical isolate of CCHFV develop a severe inflammatory

176 emonstrate that during pneumonia caused by a clinical isolate of CRKP-ST258 (KP35) there is an early

177 he blood of susceptible mice infected with a clinical isolate of M. tuberculosis resembles that of ac

178 A clinical isolate of measles virus (MeV) bearing a single

179 A clinical isolate of methicillin-resistant S. aureus was

180 a focus-reduction neutralization test with a clinical isolate of SARS-CoV-2 at biosafety level 3.

181 DNA clone of ZIKV that was generated using a clinical isolate of the Asian lineage.

182 A total of 78 clinical isolates of 13 Gram-negative species collected

183 and rescues mice from lethal infections with clinical isolates of Acinetobacter baumannii, Klebsiella

184 all 1,575 available GAS macrolide-resistant clinical isolates of all infection types collected at th

185 MDMs were infected with CF clinical isolates of B. cenocepacia and P. aeruginosa.

186 vitro against numerous fluconazole-resistant clinical isolates of C. albicans and non-albicans specie

187 with MICs ranging from 3 to 800 muM against clinical isolates of C. difficile.

188 aureomycin) were further screened against 20 clinical isolates of C. difficile.

189 riking difference between genital and ocular clinical isolates of Chlamydia trachomatis is that only

190 ones and extended-spectrum cephalosporins in clinical isolates of E. coli.

191 ate that pulmonary endothelium infected with clinical isolates of either Pseudomonas aeruginosa, Kleb

192 The practice of screening clinical isolates of Enterobacteriaceae that test as sus

193 our mutant OmpC proteins from four different clinical isolates of Escherichia coli obtained sequentia

194 splayed activity against multidrug-resistant clinical isolates of Escherichia coli, Acinetobacter bau

195 s urease activity in vitro, including recent clinical isolates of Escherichia coli, Enterococcus faec

196 ry concentrations (MICs) of imipenem against clinical isolates of Eschericia coli and Klebsiella pneu

197 It is widely held that clinical isolates of human cytomegalovirus (HCMV) are hi

198 e prevalence of the filamentous phenotype in clinical isolates of IAV.

199 substantial expansion to include a number of clinical isolates of important Gram-negative species-Ent

200 submicromolar efficacy against several human clinical isolates of influenza A viruses, including both

201 With this method, we have detected clinical isolates of influenza in just one minute, signi

202 molecules rapidly accumulated in respective clinical isolates of interest including MDROs such as me

203 serotype 3 strains emerge frequently within clinical isolates of invasive diseases.

204 ted the first ten carbapenem non-susceptible clinical isolates of K pneumoniae or E coli and ten susc

205 ta suppresses growth of antibiotic-resistant clinical isolates of Klebsiella pneumoniae, Escherichia

206 human macrophages infected with 3 ATCC and 5 clinical isolates of L.V. guyanensis, and L.V. panamensi

207 gainst antimonials and miltefosine-resistant clinical isolates of Leishmania infantum, indicating its

208 ddition to the reference strain, independent clinical isolates of M. abscessus also readily establish

209 s and found that PRELP binds the majority of clinical isolates of M. catarrhalis (n = 49) through int

210 Clinical isolates of M. tuberculosis differed in their a

211 Clinical isolates of M. tuberculosis from both Egypt and

212 rug-resistant and extensively drug-resistant clinical isolates of M. tuberculosis, suggesting that PI

213 against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis.

214 ently shown to be rapidly fungicidal against clinical isolates of MDR C. albicans in vitro.

215 aeruginosa, Staphylococcus aureus (including clinical isolates of MRSA and MSSA) and Staphylococcus e

216 identifying ofloxacin resistance in cultured clinical isolates of Mtb and benchmark its performance w

217 uated for their ability to inhibit growth of clinical isolates of multidrug-resistant ESKAPE pathogen

218 ty by multiple methods with 96 KPC-producing clinical isolates of multiple strains and species collec

219 een reported in rpoB in rifampicin-resistant clinical isolates of Mycobacterium tuberculosis (Mtb).

220 othiomalate and aurothioglucose inhibited 48 clinical isolates of N. gonorrhoeae including multidrug-

221 i clinical isolates and approximately 50% of clinical isolates of P. aeruginosa from chronic airway i

222 compounds showed increased activity against clinical isolates of P. aeruginosa, further confirming t

223 to prevent reticulocyte invasion by multiple clinical isolates of P. vivax.

224 In clinical isolates of PBMCs from lymphangioleiomyomatosis

225 Inspired by new data from 28 clinical isolates of Pseudomonas aeruginosa and strains

226 We identified here melanogenic clinical isolates of Pseudomonas aeruginosa with large c

227 Multiple clinical isolates of Pseudomonas aeruginosa, an importan

228 ed, supernatants from laboratory strains and clinical isolates of S. aureus caused galectin-3 degrada

229 ervation of nonsynonymous SNPs in fnbA among clinical isolates of S. aureus that cause endovascular i

230 lt, particularly in the context of divergent clinical isolates of S. aureus.

231 r results are broadly applicable to emerging clinical isolates of S. marcescens causing bacteremia.

232 was to determine the species diversity of 23 clinical isolates of Schizophyllum from the United State

233 livery into bacteria, we show that they kill clinical isolates of several multidrug-resistant bacteri

234 work was to study different types of ICEs in clinical isolates of the emergent pathogen Shewanella sp

235 Clinical isolates of the opportunistic pathogen Pseudomo

236 nce and mechanisms of heteroresistance in 41 clinical isolates of the pathogens Escherichia coli, Sal

237 se respiratory infection model, we show that clinical isolates often responsible for CA infections ar

238 olate subset used in this study included 620 clinical isolates originating from 455 LRTI culture-posi

239 ntaining 20 KPC-positive and 80 KPC-negative clinical isolates, performed in triplicate (300 runs) de

240 nsional confocal microscopy to visualize the clinical isolate PMSS1 and an isogenic straight-rod muta

241 Fewer than 1% of the clinical isolates possessed the mecC gene, confirming th

242 pe appeared to be more virulent, most of our clinical isolates presented belonged to (-) mating type.

243 philus probiotic was the most adherent, many clinical isolates produced greater amounts of H(2)O(2),

244 tudies performed using a panel of 80 curated clinical isolates, rates of essential and categorical ag

245 We sequenced the genomes of 133 clinical isolates recovered from 24 tertiary care hospit

246 r associated phenotypes of 208 S. pneumoniae clinical isolates representing at least 30 serotypes.

247 ntegrated analysis across 22 M. tuberculosis clinical isolates, representing ancient (lineage 1) and

248 45/145) for the 38 reference strains and 145 clinical isolates, respectively.

249 In contrast, deleting hmgR in two clinical isolates resulted in mutants that grew signific

250 combination against a panel of M. abscessus clinical isolates, revealing the therapeutic potential o

251 We used genome sequences of 52 clinical isolates sampled in New Hampshire in 2017, incl

252 in from Scotland than the low-passage-number clinical isolate SD90e from South Africa or laboratory s

253 These three sub-clades account for 91% of clinical isolates sequenced in our study.

254 In these clinical isolates, several gyrA and gyrB mutations confe

255 Seven clinical isolates shared genotypes identical to environm

256 specificity (100%) when challenged with 145 clinical isolate-spiked fecal specimens.

257 ion experiments for two T. asahii strains, a clinical isolate stain CBS 2479 (T2) and an environmenta

258 89 isolates (including 50 human and 4 animal clinical isolates) stored in the National Collection of

259 y parallel first reporting of these genes in clinical isolates, suggesting ARGs in animal manure and

260 es, genotypically indistinguishable from the clinical isolate, supporting for the first time the dire

261 of shedding in the feces differed among the clinical isolates tested.

262 expression profile of a CRE Escherichia coli clinical isolate that is sensitive to meropenem but resi

263 f reversion for this strain and for a second clinical isolate that reverts at a similar frequency.

264 ast with the trend of increasing resistance, clinical isolates that have reverted to susceptibility r

265 ntified genetic elements over-represented in clinical isolates that increased in frequency throughout

266 ere as MS-AFST, was assessed with a panel of clinical isolates that were selected to represent phenot

267 Compared with a clinical isolate, the infectious-clone-derived SARS-CoV-

268 Validated using a set of clinical isolates, the algorithm correctly identified RR

269 tion of Mycobacterium tuberculosis lineage 4 clinical isolates, the most geographically widespread ca

270 We studied putative serotype 35B clinical isolates to assess the uniformity of their sero

271 ology when determining the susceptibility of clinical isolates to cefepime-enmetazobactam.

272 ant Pseudomonas aeruginosa strains including clinical isolates to exploit the versatility of the dite

273 and gene expression values of a plethora of clinical isolates to give a consensus DNA sequence and c

274 Here we combine computational analysis of clinical isolates, transcriptomics, metabolic modeling a

275 ntyphoidal Salmonella Typhimurium LT2, and a clinical isolate Typhimurium D23580.

276 One clinical isolate was killed more effectively in azithrom

277 The clade of 11 C. acnes clinical isolates was determined by MLST.

278 e PLA and intestinal-colonizing K pneumoniae clinical isolates was examined.

279 inosa laboratory strains, but its effects in clinical isolates was unknown.

280 Comparing the host response to two clinical isolates, we identify distinct immune response

281 arbapenem-resistant Enterobacteriaceae (CRE) clinical isolates, we reveal the underlying basis for th

282 In the largest ever study of clinical isolates, we surveyed adhesion of freshly colle

283 nt P. aeruginosa NCTC 13437 and an unrelated clinical isolate were used to infect G. mellonella larva

284 Clinical isolates were collected from patients diagnosed

285 99 A. defectiva, G. adiacens, and G. elegans clinical isolates were determined by broth microdilution

286 Multiplication rates of eleven new clinical isolates were measured after a few weeks of cul

287 m laboratory adapted parasite clones and new clinical isolates were measured, using a newly standardi

288 385 Mycobacterium tuberculosis clinical isolates were processed for BMD and whole genom

289 The S. halichoeri type strain and the human clinical isolates were susceptible to the antimicrobials

290 s observed when they were tested against six clinical isolates, which included extensively drug-resis

291 rmed genomic and plasmid sequencing of three clinical isolates with both MinION and Illumina MiSeq, u

292 revealed that while Fusobacterium nucleatum clinical isolates with FadA and Fap2 adhesins failed to

293 were confirmed in infection experiments with clinical isolates with known cagA status and in human ga

294 We used naturally occurring clinical isolates with rocA polymorphisms (n = 48), an i

295 Finally, we show that clinical isolates with significantly higher extracellula

296 coli) reference strains and was tested on 51 clinical isolates with well-characterized resistance phe

297 esults confirm the potency of INSTI on HIV-2 clinical isolates with wild-type integrase.

298 We utilized paired clinical isolates, with the parent (susceptible) strain

299 DNA extracted from E. coli or K. pneumoniae clinical isolates within a few minutes.

300 WGS clustered food, environmental, and clinical isolates within each outbreak, and also differe