ライフサイエンスコーパス: clinical manifestation

1 ding readouts of early disease states before clinical manifestation.

2 ent to detect AD in its earlier stage before clinical manifestation.

3 ple phenotypes, with epilepsy being the main clinical manifestation.

4 correlation between mutations and individual clinical manifestation.

5 (AD), driving initial cognitive deficits and clinical manifestation.

6 NSAIDH overdiagnosis when anaphylaxis is the clinical manifestation.

7 ics and thus a deeper understanding of their clinical manifestation.

8 serostatus, year and organ transplanted, and clinical manifestation.

9 iral genetic changes could contribute to new clinical manifestations.

10 mproved our understanding of the spectrum of clinical manifestations.

11 V lymphotropism and promote goose parvovirus clinical manifestations.

12 tionship between spinal cord involvement and clinical manifestations.

13 n specific brain regions resulting in severe clinical manifestations.

14 ther closely related infections with similar clinical manifestations.

15 slowly progressing disorder with multisystem clinical manifestations.

16 adipose tissue fibrosis and its relevance to clinical manifestations.

17 dormant infection in the kidney with minimal clinical manifestations.

18 persistent EBV-infected T cells but without clinical manifestations.

19 l follow-up of disease course in relation to clinical manifestations.

20 der with various contributing mechanisms and clinical manifestations.

21 tic revertant mosaicism commonly ameliorated clinical manifestations.

22 family B heterozygotes had less severe or no clinical manifestations.

23 uman mitochondrial diseases with pleiotropic clinical manifestations.

24 D-associated gene mutations alleviates their clinical manifestations.

25 disease (SVD) underlying different potential clinical manifestations.

26 the striatum and red nuclei with the ensuing clinical manifestations.

27 omiting (54% [29 of 54]) were common initial clinical manifestations.

28 econstituted B cell compartment with ensuing clinical manifestations.

29 olerance to nucleic acids and highly diverse clinical manifestations.

30 an systems are affected causing a variety of clinical manifestations.

31 major GRDs that present with a wide range of clinical manifestations.

32 variants in ENG, ACVRL1, SMAD4 and GDF2, and clinical manifestations.

33 ergic reaction that may have a wide range of clinical manifestations.

34 r virus (VZV) are associated with a range of clinical manifestations.

35 lant recipients and be able to recognize the clinical manifestations.

36 fect of mutations in these enzymes and their clinical manifestations.

37 man developmental disorders with overlapping clinical manifestations.

38 athies of infancy and childhood with diverse clinical manifestations.

39 ease and can lead to extremely heterogeneous clinical manifestations.

40 HbF tend to have less severe or even minimal clinical manifestations.

41 ia in blood or tissue and eosinophil-related clinical manifestations.

42 ay progress to severe disease with different clinical manifestations.

43 and IGLV1-44) and the general improvement of clinical manifestations after PC clone-targeted treatmen

44 disorders are monogenetic diseases; however, clinical manifestations among individuals vary, despite

45 entary approach to understanding patterns of clinical manifestation and inter-individual variation in

46 m admission, being related to the presenting clinical manifestation and markers of myocardial injury

47 to June 2018 in the Netherlands and assessed clinical manifestation and symptoms at disease onset and

48 hese surveillance data help characterize the clinical manifestations and adverse outcomes of Zika vir

49 is increasing, and it presents with various clinical manifestations and an unfavorable survival rate

50 Inflammation plays a crucial role in clinical manifestations and complications of acute coron

51 Although clinical manifestations and diagnostic tools (including

52 ntial individual heterogeneity exists in the clinical manifestations and duration of active tuberculo

53 To describe clinical manifestations and epidemiology of Zika virus d

54 Objective: To describe clinical manifestations and epidemiology of Zika virus d

55 tissues and fluids, which contributes to the clinical manifestations and epidemiology that have been

56 However, despite sharing some clinical manifestations and immune dysregulation, diseas

57 Data about clinical manifestations and laboratory findings were ret

58 niosis (CanL) is complex due to its variable clinical manifestations and laboratory findings.

59 The change in clinical manifestations and management over the past 2 d

60 We used logistic regression to compare clinical manifestations and mortality of IMD-W with IMD

61 nce was generally associated with mild or no clinical manifestations and often with mild glomerular m

62 This study characterizes the clinical manifestations and outcome of a large cohort of

63 The clinical manifestations and outcome of these cases are d

64 ontribution of additional genetic lesions to clinical manifestations and outcome.

65 y myeloid neoplasia with a broad spectrum of clinical manifestations and outcomes in children.

66 is needed to link inflammatory endotypes to clinical manifestations and outcomes in COPD and in part

67 We evaluated the clinical manifestations and outcomes of patients with sa

68 ological subtype of HCC with largely unclear clinical manifestations and outcomes.

69 esented, along with a review of the biology, clinical manifestations and pathology in the human host,

70 ecisions, which are likely important for the clinical manifestations and pathology of allergic skin d

71 rleukin-6 (IL-6) activity, may be related to clinical manifestations and pathophysiology of schizophr

72 The heterogeneity of its clinical manifestations and the differential responses t

73 be difficult to diagnose due to its diverse clinical manifestations and the inadequacy of convention

74 needs to be done to improve awareness of its clinical manifestations and the potential of therapeutic

75 but are also markers of preeclampsia before clinical manifestation, and are associated with adverse

76 It is heterogeneous in etiology, clinical manifestations, and course.

77 iew, we discuss aspects of the epidemiology, clinical manifestations, and diagnosis of cystic echinoc

78 utaminase antibodies, questionnaire results, clinical manifestations, and histological findings were

79 ecific symptoms, chronic and cryptic protean clinical manifestations, and lack of clinician awareness

80 ependent predictor of HFpEF risk, associated clinical manifestations, and long-term outcomes.

81 few studies have examined the risk factors, clinical manifestations, and outcomes of CDI in this pop

82 what the implications are for pathogenesis, clinical manifestations, and therapy.

83 or our understanding of the pathophysiology, clinical manifestations, and treatment of the disorder.

84 The clinical manifestations are associated with structural a

85 Prominent clinical manifestations are headache, subacute encephalo

86 Atherosclerosis and its clinical manifestation as ischaemic heart disease remain

87 We performed a prospective cohort study of clinical manifestations as well as imaging, pathology, C

88 epithelial immune compartment to promote the clinical manifestations associated with food-triggered a

89 ls will help to better define phenotypes and clinical manifestations associated with respiratory dise

90 We sought to understand the clinical manifestations associated with the X-linked CGD

91 main asymptomatic or present with a range of clinical manifestations associated with West Nile fever.

92 group of inherited disorders sharing several clinical manifestations because of abnormal cilia format

93 Organ involvement determines the clinical manifestations, but symptoms are usually recogn

94 Despite having serious clinical manifestations, Cellulosimicrobium cellulans re

95 often considered rare disorders with protean clinical manifestations, considerable advances in the un

96 Clinical manifestations depend on the involved organs, r

97 To describe patient characteristics, clinical manifestations, disease course including viral

98 are noted in epidemiology, pathophysiology, clinical manifestations, disease progression, and respon

99 Clinical manifestations due to increased intracranial pr

100 ugh these diseases are wide ranging in their clinical manifestations, each can potentially be treated

101 cle, we discuss the disease pathophysiology, clinical manifestation, evidence based recommendations f

102 natory level, between neural dysfunction and clinical manifestations, for characterizing neuropsychia

103 gal pathogens that can cause a widely varied clinical manifestation from mild pulmonary symptom to di

104 me coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild, self-

105 Yet the cost of its clinical manifestation has created a disease of its own:

106 A wide spectrum of clinical manifestations has become a hallmark of the sev

107 The patients were diagnosed by clinical manifestations, histopathology, and immunoepito

108 the underlying etiology (i.e., endotype) and clinical manifestation (i.e., phenotype) of OSA in an in

109 hese findings represent the substrate of the clinical manifestations (i.e. myoclonus) of the photopar

110 ical alterations in the striatum and related clinical manifestations (i.e., craving and persistence o

111 biopsy results, the positive c-ANCA, and the clinical manifestation, i.e., heart and ocular involveme

112 from 10 unrelated families with overlapping clinical manifestations identified loss-of-function and

113 rum of the disorder, including demographics, clinical manifestations, imaging features, natural cours

114 However, their clinical manifestation, immunohistology, and gene expres

115 nd the immunocompromised population, but its clinical manifestations, impact, and outcomes in hospita

116 The most typical clinical manifestations in all 5 patients were sleep dis

117 y contribute to the circadian variability of clinical manifestations in asthma and allergy.

118 Clinical manifestations in canine visceral leishmaniasis

119 rus 2 (SARS-CoV-2) has shown a wide range of clinical manifestations in different patient populations

120 licated genes or groups of genes to the many clinical manifestations in DS.

121 ulation in tissues associated with long-term clinical manifestations in humans.

122 lowed patients in Rio de Janeiro to describe clinical manifestations in mothers and repercussions of

123 ng has been the wide-ranging presentation of clinical manifestations in patients with mt-aaRS mutatio

124 sporadic ZIKV cases were reported, with mild clinical manifestations in patients.

125 Clinical manifestations in TB are consequences of comple

126 Clinical manifestations include encephalitis, meningitis

127 Its major clinical manifestations include ischemic heart disease,

128 target of congenital CMV is the brain, with clinical manifestations including mental retardation, vi

129 idemic has been linked to unusual and severe clinical manifestations including microcephaly in fetuse

130 on's disease (PD) is associated with diverse clinical manifestations including motor and non-motor si

131 Lassa fever (LF) survivors develop various clinical manifestations including polyserositis, myalgia

132 BS is characterized by multiple clinical manifestations including predisposition to a wi

133 athogen that has been associated with severe clinical manifestations, including devastating neurologi

134 ncy can be accompanied by a wide spectrum of clinical manifestations, including progressive blindness

135 The prevalence of clinical manifestations increased broadly from index eva

136 The biochemistry and clinical manifestations indicate that these patients hav

137 physiological mechanisms lead to an array of clinical manifestations involving numerous organ systems

138 how spinal cord abnormalities translate into clinical manifestations is incomplete.

139 This study evaluated the clinical manifestations, laboratory findings, and molecu

140 Few data are available on its clinical manifestations, laboratory findings, and outcom

141 This retrospective study compared the clinical manifestations, laboratory parameters, and imag

142 The clinical manifestations largely depend on the differenti

143 We aimed to describe the clinical manifestations, management and in-ICU and 6-mon

144 Clinical manifestation may range from asymptomatic to in

145 APC activation may explain many of the clinical manifestations (microangiopathy, thrombocytopen

146 In this Seminar, we concentrate on clinical manifestations, molecular pathogenesis, diagnos

147 peat number (RN) with AAO (n = 295), initial clinical manifestation (n = 294), site of dystonia onset

148 ream NF-kappaB activation, characteristic of clinical manifestation of a prolonged fever.

149 endent learning patterns emerge prior to the clinical manifestation of a relapse, predicting its timi

150 elated ischemic strokes, stroke is the first clinical manifestation of AF.

151 growth factor (VEGF) is associated with the clinical manifestation of Alzheimer's disease (AD).

152 oing surgery with (n=131) or without (n=128) clinical manifestation of ASCVD.

153 Hitherto, the clinical manifestation of ATR deficiency has been attrib

154 cular ejection fraction, irrespective of the clinical manifestation of cardiomyopathy.

155 stage of parasite development results in the clinical manifestation of disease.

156 The most common clinical manifestation of early Lyme disease is the eryt

157 a is a major and currently poorly understood clinical manifestation of hematopoietic aging.

158 ights into the details of each HF subgroup's clinical manifestation of HF.

159 In patients with delayed graft function, a clinical manifestation of IRI, these cells were Ki-67+IL

160 Erythema migrans is the most common clinical manifestation of Lyme disease.

161 The clinical manifestation of moderate to severe COVID-19 ha

162 The clinical manifestation of NIID varies widely, and both f

163 ibution, antimicrobial resistance (AMR), and clinical manifestation of NTS gastroenteritis in Vietnam

164 These results illuminate the overlooked clinical manifestation of persistent salmonellosis that

165 expression changes, despite an observed mild clinical manifestation of the disease.

166 evere Mendelian conditions, with no reported clinical manifestation of the indicated disease.

167 In humans, clinical manifestation of tics cannot be captured via fu

168 heter-related septicemia is one of the major clinical manifestations of A. baumannii infection associ

169 cling and that its absence may aggravate the clinical manifestations of ABCA12 mutations.

170 erations in young individuals, preceding the clinical manifestations of AD.

171 ble and may provide further insight into the clinical manifestations of altered hemodynamics in HCM.(

172 The non-cognitive clinical manifestations of Alzheimer's disease seem to a

173 torhinal cortex to the neocortex, before the clinical manifestations of Alzheimer's disease.

174 While clinical manifestations of anti-interferon-gamma (IFN-ga

175 These phenotypes recapitulate the clinical manifestations of arCRD patients.

176 lationship between inflammatory pathways and clinical manifestations of asthma may lead to more indiv

177 as a new candidate for the treatment of the clinical manifestations of atherosclerosis.

178 t tumour suppressive function leading to the clinical manifestations of BHD, whereas the FLCN K508R m

179 ilateral multifocal (BMF) kidney tumours and clinical manifestations of Birt-Hogg-Dube (BHD) syndrome

180 Clinical manifestations of both HLH subtypes are often p

181 The clinical manifestations of CDI and patient outcomes were

182 In this review, the clinical manifestations of CHIKV that define the disease

183 individual patient presenting with different clinical manifestations of coronary atherothrombosis, in

184 Although the clinical manifestations of COVID-19 are dominated by res

185 Clinical manifestations of COVID-19 caused by the new co

186 ndamental processes underlying the versatile clinical manifestations of COVID-19 is incomplete withou

187 l and immunological processes underlying the clinical manifestations of COVID-19 is vital for the ide

188 Clinical manifestations of COVID-19 vary, ranging from a

189 issue modeling processes may account for the clinical manifestations of CRS.

190 Clinical manifestations of cystic fibrosis (CF) result f

191 The clinical manifestations of DED can be highly variable; h

192 and treatments may affect the prevalence and clinical manifestations of diabetic kidney disease.

193 rmacological inhibition of HIF-1 may improve clinical manifestations of diabetic nephropathy.

194 ma (ATLL) can be identified years before the clinical manifestations of disease are apparent.

195 uce endogenous complement, were required for clinical manifestations of disease, a finding that sugge

196 immunogenicity, disease susceptibility, and clinical manifestations of disease.

197 rtance of cerebro-cerebellar networks in the clinical manifestations of DS and suggest a role for DTB

198 es literature detailing risk factors for and clinical manifestations of EVD, laboratory and other inv

199 alamus and cortex are mostly responsible for clinical manifestations of FFI.

200 gen passaging in mice inhibited induction of clinical manifestations of FIA.

201 Clinical manifestations of food allergy are largely medi

202 activation that elicited protection against clinical manifestations of food allergy in two mouse mod

203 iseases are present in all human cells; yet, clinical manifestations of genetic diseases are usually

204 Clinical manifestations of glycocalyx degradation in unr

205 ensional approach would better delineate the clinical manifestations of goal-directed deficits.

206 Importantly, GPgV could promote clinical manifestations of goose parvovirus infection, i

207 ion of cytokine release syndrome, resembling clinical manifestations of HLH.

208 ably undiagnosed, this review emphasizes the clinical manifestations of HNF1beta-associated disease f

209 mmissures are widely disrupted, thus causing clinical manifestations of horizontal gaze palsy, scolio

210 Back-translating the clinical manifestations of human disease burden into ani

211 nd pathogenesis that fully recapitulates the clinical manifestations of human infections.

212 Clinical manifestations of hypothyroidism range from lif

213 The clinical manifestations of IA are similar to other known

214 e concerning the microbiology, epidemiology, clinical manifestations of infection, treatment, and pub

215 In neonatal encephalopathy, the clinical manifestations of injury can only be reliably a

216 Different clinical manifestations of invasive pneumococcal disease

217 unclassifiable mixed MDS/MPN and mimics many clinical manifestations of JMML in terms of age of onset

218 Clinical manifestations of MAS in a given individual, in

219 Clinical manifestations of mastocytosis are mostly due t

220 This provides a potential explanation for clinical manifestations of melioidosis that are geograph

221 not elicit the loss of orexin(+) neurons or clinical manifestations of narcolepsy.

222 nifestations.SIGNIFICANCE STATEMENT Although clinical manifestations of neuropsychiatric lupus are we

223 roautophagy and how this correlates with the clinical manifestations of NSAID enteropathy, however, r

224 n the United States alone, yet patients with clinical manifestations of PAD (e.g., claudication and l

225 tained patient clusters were correlated with clinical manifestations of PADs.

226 s shed insight into the genetic spectrum and clinical manifestations of Parkinson's disease in mainla

227 We sought to compare clinical manifestations of pertactin-deficient and perta

228 Knowledge about the clinical manifestations of plague during pregnancy, spec

229 hways through which PF-06700841 improves the clinical manifestations of psoriasis.

230 Clinical manifestations of respiratory syncytial virus (

231 not significantly affect peak viral load or clinical manifestations of RSV disease.

232 ral, and structural abnormalities resembling clinical manifestations of RTT.

233 mission duration, preflight body weight, and clinical manifestations of SANS.

234 Age-related differences in the clinical manifestations of SARS-CoV-2 infection must be

235 ents and to describe demographic factors and clinical manifestations of seropositive patients.

236 6 of 17 (94%) of sputum ANCA(+) patients had clinical manifestations of severe asthma compared with 3

237 Osteoporosis or osteopenia are common clinical manifestations of sickle cell disease (SCD) wit

238 Clinical manifestations of sickle cell disease were redu

239 ying autoantibodies associated with relevant clinical manifestations of SLE, with potential for use a

240 cell-based assay system to help explain the clinical manifestations of some otherwise puzzling GGCX

241 odel systems that recapitulate mutations and clinical manifestations of specific PMDs are evaluated f

242 s a significant role as a buffer against the clinical manifestations of SVD and may in part explain h

243 achieved complete resolution of pruritus and clinical manifestations of the disease, as well as norma

244 nocytes, and there was no improvement in the clinical manifestations of the Dsg3(-/-) mice.

245 challenging because the typical and atypical clinical manifestations of the GRDs overlap.

246 Clinical manifestations of this disease include congenit

247 risk factors to atheroma development and the clinical manifestations of this disease.

248 The clinical manifestations of TS are complex and often over

249 oring, changes in laboratory parameters, and clinical manifestations of tumour lysis syndrome, and th

250 to minimise the risk of both laboratory and clinical manifestations of tumour lysis syndrome.

251 lation of L. (L.) amazonensis from dogs with clinical manifestations of visceral leishmaniasis in Gov

252 duce a disease known as Majeed syndrome, the clinical manifestations of which are ameliorated by stra

253 t Zika virus (ZIKV) outbreaks and unexpected clinical manifestations of ZIKV infection have prompted

254 iopathies in which RD may be either the sole clinical manifestation or part of a syndrome, our findin

255 vidence of a beneficial effect on any of the clinical manifestations or on dengue viremia.

256 We analyzed the causative PPI, clinical manifestations, organ involvement, treatment, a

257 Clinical manifestations owing to l-ascorbic acid for scu

258 le-gene disorders, including their genetics, clinical manifestations, pathogenesis, and treatment.

259 For most multigenic disorders, clinical manifestation (penetrance) and presentation (ex

260 induced) is key to a better understanding of clinical manifestations, prognostic implications, as wel

261 he rise of Zika virus (ZIKV) and its unusual clinical manifestations provided ground for speculative

262 ld promote deep infection with limited early clinical manifestations, raising concerns that bacterial

263 The clinical manifestations range from subclinical infection

264 inflammatory condition of the pancreas with clinical manifestations ranging from abdominal pain, acu

265 e coronavirus 2, leads to a wide spectrum of clinical manifestations ranging from asymptomatic cases

266 Mycoplasma infections include a spectrum of clinical manifestations ranging from simple fever to ful

267 Pathogenic Salmonella serovars produce clinical manifestations ranging from systemic infection

268 agnostic evaluation and the heterogeneity of clinical manifestations, ranging from fetal hydrops and

269 The disease has many clinical manifestations, ranging from severe malabsorpti

270 it is not clear whether differences exist in clinical manifestations relative to KS1.

271 onstrates signature attributes that parallel clinical manifestations seen in humans and provides a vi

272 genetic hemoglobinopathy leading to 2 major clinical manifestations: severe chronic hemolytic anemia

273 However, the clinical manifestations show unprecedented variability,

274 singly utilized model of pathogenesis due to clinical manifestations similar to those for HIV-1 infec

275 turn from self-limiting diarrhea into severe clinical manifestation such as colonic necrosis-if intes

276 the diagnosis as a potential cause of common clinical manifestations such as cytopenias and immune dy

277 eactivity, and similar but often less severe clinical manifestations, such as dengue and chikungunya

278 Multiple clinical manifestations, such as enlarged kidneys filled

279 potentially include (i) treatment of severe clinical manifestations, such as pneumonitis or eye comp

280 temporospatial spread of Tau observed during clinical manifestation suggests that Tau pathology may s

281 h donor cells, although the heterogeneity of clinical manifestations suggests that patient, donor, an

282 nabled identification of classes with common clinical manifestations that are hidden under the curren

283 he association between rs1801198 and MMA and clinical manifestations that are linked to a decreased a

284 and refractory process showing age-dependent clinical manifestations that are mechanistically undefin

285 fections are associated with a wide range of clinical manifestations that are of public health import

286 nephrotoxicity, as well as the wide range of clinical manifestations that have been reported with the

287 cesses begin decades before the onset of the clinical manifestations, the study of the cortical distr

288 diomyopathies have similar morphological and clinical manifestations, their outcomes differ significa

289 However, in patients presenting persistent clinical manifestations, this indirect diagnosis is not

290 from chronic periodontitis (CP) in terms of clinical manifestations, this study investigates whether

291 of disease severity in mTLE before its first clinical manifestations, thus expanding the therapeutic

292 ic sclerosis (SSc) and is often the earliest clinical manifestation to occur.

293 ) RDT has higher sensitivity than the use of clinical manifestations to detect severe malaria, making

294 as a group are diverse in their origins and clinical manifestations; we use the well-described Diamo

295 No detectable clinical manifestations were observed.

296 However none of these clinical manifestations were significantly associated wi

297 al vasculature that differ in physiology and clinical manifestations when compared with exercise-indu

298 ially in children and could have overlapping clinical manifestations with more common conditions.

299 e disease encompasses a variable spectrum of clinical manifestations with tegumentary or visceral sym

300 ed infection with Babesia causes no specific clinical manifestations, with many having no symptoms at