ライフサイエンスコーパス: clinical syndrome

1 tive impairment or dementia with Alzheimer's clinical syndrome).

2 Frailty is a complex and prevalent clinical syndrome.

3 of the GBA gene or lysosome function to this clinical syndrome.

4 und in genes not usually associated with the clinical syndrome.

5 king the neuroendocrine abnormalities of the clinical syndrome.

6 ot sufficient for tissue specificity and the clinical syndrome.

7 tify the image features associated with each clinical syndrome.

8 ted networks to identify regions common to a clinical syndrome.

9 pulmonary disease (74%) was the most common clinical syndrome.

10 affects the diagnosis and management of this clinical syndrome.

11 antigenic specificity of ANCA, not with the clinical syndrome.

12 Postoperative cognitive decline is a clinical syndrome.

13 novel in the Americas, is the cause of this clinical syndrome.

14 enetic concordance of VGS for a well-defined clinical syndrome.

15 s are rare neoplasms often associated with a clinical syndrome.

16 tional valvular heart disease, mimicking the clinical syndrome.

17 redict the underlying pathology based on the clinical syndrome.

18 ce, outcomes, and risk factors of this novel clinical syndrome.

19 ble dementia with Lewy bodies, and Alzheimer clinical syndrome.

20 nt serogroup, age distribution of cases, and clinical syndrome.

21 ltured from a sterile site with a compatible clinical syndrome.

22 questions concerning the entire spectrum of clinical syndromes.

23 erent genotypic networks that cause distinct clinical syndromes.

24 ic networks associated with several distinct clinical syndromes.

25 ing Mycobacterium causing a wide spectrum of clinical syndromes.

26 d broadening the phenotypic spectrum of many clinical syndromes.

27 sly shown to correlate with isolates causing clinical syndromes.

28 tant human pathogens associated with various clinical syndromes.

29 o show significant association with specific clinical syndromes.

30 a disorder rather than in relation to broad clinical syndromes.

31 recapitulated the core features of the main clinical syndromes.

32 s is characteristic of many fibrosis-related clinical syndromes.

33 f these common crystals and their associated clinical syndromes.

34 natives to ACE inhibitors in these important clinical syndromes.

35 bution of isolates associated with different clinical syndromes.

36 sity to secrete hormones that cause distinct clinical syndromes.

37 ng the aetiologies underlying neurocognitive clinical syndromes.

38 and each can present with several different clinical syndromes.

39 When subjects were grouped by clinical syndrome, additional trends were discernable, h

40 Viral bronchiolitis is a common clinical syndrome affecting infants and young children.

41 t-sided heart failure which causes a complex clinical syndrome affecting multiple organ systems inclu

42 Heart failure (HF) is a complex clinical syndrome affecting roughly 26 million people wo

43 progranulin gene are known to cause diverse clinical syndromes, all attributed to frontotemporal lob

44 Using a classification based on clinical syndrome alone gave a higher estimate of the fr

45 Peripheral neuronopathy is often part of the clinical syndrome and can represent the most disabling f

46 poral lobes, lateralising according to their clinical syndrome and evident in raw images.

47 Age at clinical onset, clinical syndrome and family history each strongly predi

48 We describe how stroke presents as a clinical syndrome and how imaging as the most important

49 The clinical syndrome and laboratory evidence were consisten

50 ence that, although a single mTBI produces a clinical syndrome and pathology that remain static in th

51 ong immunocompromised patients to manage the clinical syndrome and to avoid the emergence of multidru

52 may enable better correlation with specific clinical syndromes and antibiotic resistance patterns.

53 tanding of FTLD both as a set of distinctive clinical syndromes and as a set of disorders with unique

54 d is complicated by a barrage of overlapping clinical syndromes and histopathological diagnoses that

55 understanding of the correspondence between clinical syndromes and histopathological subtype: strong

56 Recent studies of clinical syndromes and neuropathological studies are com

57 e important, associations between individual clinical syndromes and neuropathology.

58 le, aged 52-84 years, representing the major clinical syndromes and representative pathogenic mutatio

59 ungal infections based on host-risk factors, clinical syndromes and specific pathogens.

60 ciation of K. kingae genotypes with specific clinical syndromes and the temporal and geographic distr

61 at relate to and inform our understanding of clinical syndromes and to exploration of the epigenome,

62 to clarify biological relationships between clinical syndromes (and thus also ways of extending indi

63 Heart failure is a burdensome clinical syndrome, and patients and their caregivers are

64 challenging since there is no pathognomonic clinical syndrome, and the organism is often misidentifi

65 lassification scheme, a review of associated clinical syndromes, and a summary of the performance and

66 c pathogens have identified novel pathogens, clinical syndromes, and sequelae; described new reservoi

67 eration are associated with several distinct clinical syndromes, and the corticobasal syndrome has be

68 lihood of discovery of a causal variant in a clinical syndrome, are conspicuously absent from the lit

69 al grey matter, we propose to redefine these clinical syndromes as 'the behavioural/dysexecutive vari

70 umatic encephalopathy syndrome, the putative clinical syndrome associated with chronic traumatic ence

71 totemporal dementia (bvFTD)--the most common clinical syndrome associated with frontotemporal lobar d

72 e propose a new diagnostic construct for the clinical syndrome associated with repetitive exposure to

73 Pregnancy-associated malaria is a severe clinical syndrome associated with the sequestration of P

74 mmarize trends among the major pathogens and clinical syndromes associated with antibiotic resistant

75 course of infantile hemangiomas, describing clinical syndromes associated with infantile hemangiomas

76 inding of a low urine pH in individuals with clinical syndromes associated with insulin resistance an

77 Clinical syndromes associated with progressive supranucl

78 t pathological differences between the major clinical syndromes associated with PSP-tau pathology and

79 In three families with clinical syndromes associated with short telomeres resul

80 The clinical syndromes associated with VGKC complex (VGKCC)

81 nts with a positive PCR and a compatible PCP clinical syndrome, BDG had a sensitivity of 70%, specifi

82 The clinical syndrome begins with abnormal placentation with

83 However, the most common clinical syndrome (behavioural variant frontotemporal de

84 lar pathological finding, but also different clinical syndromes (both acute and progressive), brain p

85 seroconversion in patients with a compatible clinical syndrome but without erythema migrans.

86 n characteristic lesions accompany a typical clinical syndrome, but in some patients, further support

87 ntributes to elevated blood pressure (BP) in clinical syndromes, but its effect on BP in the physiolo

88 Collectively, these results define a clinical syndrome caused by haploinsufficiency of YY1 th

89 Shigellosis is a clinical syndrome caused by invasion of the epithelium l

90 Sepsis is a series of clinical syndromes caused by the immunological response

91 Primary progressive aphasia (PPA) is a clinical syndrome characterised by progressive decline i

92 Myoclonus-dystonia (M-D) is a clinical syndrome characterized by a combination of myoc

93 emarkably similar to those observed in SD, a clinical syndrome characterized by a progressive breakdo

94 Acute respiratory distress syndrome is a clinical syndrome characterized by a refractory hypoxemi

95 ltaneously and sequentially to result in the clinical syndrome characterized by a rise in serum creat

96 Hyperekplexia or startle disease is a rare clinical syndrome characterized by an exaggerated startl

97 Portal hypertension is a clinical syndrome characterized by an increase in the po

98 ica (NMO; also known as Devic syndrome) is a clinical syndrome characterized by attacks of acute opti

99 Gastroparesis is a chronic clinical syndrome characterized by delayed gastric empty

100 Heart failure is a clinical syndrome characterized by dyspnea or exertional

101 Alcoholic hepatitis is a clinical syndrome characterized by jaundice and liver im

102 of primary progressive aphasia (svPPA) is a clinical syndrome characterized by neurodegeneration and

103 Tolosa-Hunt syndrome is a rare clinical syndrome characterized by painful ophthalmopleg

104 ll-blown abdominal compartment syndrome is a clinical syndrome characterized by progressive intra-abd

105 Heart failure (HF) is a clinical syndrome characterized by signs and symptoms in

106 conceptual definition of heart failure as a clinical syndrome characterized by symptoms that are ass

107 d multiple system atrophy (MSA) are distinct clinical syndromes characterized by the pathological acc

108 of serologic testing in patients with select clinical syndromes compatible with disseminated Lyme dis

109 o l'Hopital Gabriel Toure with high fever or clinical syndromes compatible with focal invasive bacter

110 The clinical syndrome comprising heart failure (HF) symptoms

111 ported that two siblings presenting with the clinical syndrome congenital disorders of glycosylation

112 The donor had a clinical syndrome consistent with Balamuthia infection a

113 Women with a clinical syndrome consistent with unstable ischemic hear

114 Primary progressive aphasia is a clinical syndrome defined by progressive deficits isolat

115 ibuted human malaria parasite, causes severe clinical syndromes despite low peripheral blood parasite

116 argue that this scenario represents a unique clinical syndrome, distinct from de novo GCTs or hematol

117 rhinovirus from patients with new or unusual clinical syndromes does not permit the assumption that r

118 This shift results in a clinical syndrome dominated by progressive cerebellar dy

119 ated acute liver failure (ALF) is a dramatic clinical syndrome due to a sudden loss of hepatic cells

120 Although HFpEF is a heterogeneous clinical syndrome, elevated left atrial pressure-either

121 ith scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution

122 lomotor abnormalities were identified in all clinical syndromes except for SD, which had oculomotor p

123 esearch has been conducted in the history of clinical syndromes, famous people and psychiatrists, psy

124 select Notch receptors and ligands to human clinical syndromes featuring blood vessel abnormalities

125 Most (89%) participants with Alzheimer clinical syndrome fell into the A+T+ quadrant.

126 In patients with a compatible clinical syndrome for PCP, higher BDG values (>200 pg/mL

127 It remains among the most challenging of clinical syndromes for the practicing clinician and scie

128 analysis of seasonality, climate region, and clinical syndromes from 243,000 verbal autopsies in the

129 factorial disease manifests as a spectrum of clinical syndromes from uncomplicated acute otitis media

130 impact of the directly measured iron on the clinical syndrome has not been assessed.

131 Distinct clinical syndromes have been associated with pathogenic

132 syndrome, DiGeorge syndrome, and some other clinical syndromes have in common a high frequency of he

133 recognized, the etiologies of many of these clinical syndromes have not been identified, and they ar

134 any organ system, and produce many distinct clinical syndromes, have emerged as essential goals of I

135 Hantavirus is known to cause 2 distinct clinical syndromes: hemorrhagic fever with renal syndrom

136 We suggest that the clinical syndrome HLH generally results from the combine

137 e associated with distinct gene products and clinical syndromes (i.e., the schizophrenias) varying in

138 endously since CPVT was first described as a clinical syndrome in 1995.

139 The mutation precisely cosegregated with the clinical syndrome in all the affected family members and

140 90, was found to cosegregate with a similar clinical syndrome in an ethnically distinct family.

141 Y RNAs may help determine the nature of the clinical syndrome in anti-Ro autoimmunity.

142 Recent reports highlight a new clinical syndrome in children related to severe acute re

143 opic dermatitis (cAD) is a common hereditary clinical syndrome in domestic dogs with no definitive di

144 ejection fraction (HFpEF) is a heterogeneous clinical syndrome in need of improved phenotypic classif

145 Frailty is a common clinical syndrome in older adults that carries an increa

146 Bacterial vaginosis (BV) is a common clinical syndrome in which the protective lactic acid-pr

147 hich are associated with florid episodic CNS clinical syndromes in addition to peripheral neuropathy.

148 istic pathogen that causes a wide variety of clinical syndromes in immuno-compromised individuals.

149 vestigating failures of cognitive control in clinical syndromes in which value assigned to stimuli co

150 .3243A>G mutation is associated with several clinical syndromes including mitochondrial encephalopath

151 important attributes of the DOCK8 deficiency clinical syndrome, including the unusual susceptibility

152 ss worldwide and are associated with diverse clinical syndromes, including asymptomatic infection, re

153 peptides and neuroamines that cause distinct clinical syndromes, including carcinoid syndrome.

154 C) strains are common causes of a variety of clinical syndromes, including urinary tract infections,

155 lia that would be expected to present with a clinical syndrome indistinguishable from Ac.

156 Sepsis is a common life-threatening clinical syndrome involving complications as a result of

157 Spatial neglect is a common clinical syndrome involving disruption of the brain's at

158 The predominant clinical syndrome is a progressive cortical dementia wit

159 of OA is complex, and its presentation as a clinical syndrome is associated with pathologies of mult

160 In such cases, if the clinical syndrome is attributed solely to transfusion-re

161 This usually reversible clinical syndrome is becoming increasingly recognised, i

162 The clinical syndrome is poorly defined, and the role of inf

163 The clinical syndrome is propelled by inflammation producing

164 In cases where hemorrhage occurs, the clinical syndrome is significantly less disabling than i

165 There is no explanation for why this clinical syndrome is so distinct from Creutzfeldt-Jakob

166 ratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus diseas

167 The clinical syndrome known as acute tubular necrosis does n

168 This novel clinical syndrome links susceptibility to mycobacterial,

169 eneration can present with several different clinical syndromes, making ante-mortem diagnosis a chall

170 Obliterative bronchiolitis (OB) is a clinical syndrome marked by progressive dyspnea and coug

171 Consideration of clinical syndrome may help improve the accuracy of ATN d

172 d other clinical findings suggest that these clinical syndromes may be better classified as PR3-posit

173 al points of modulation across heterogeneous clinical syndromes may provide insight into new therapeu

174 Accurate detection is challenging, as the clinical syndrome might be confused with either behaviou

175 Sepsis, a clinical syndrome occurring in patients following infect

176 myeloid neoplasms (t-MN) represent a unique clinical syndrome occurring in patients treated with che

177 The clinical syndrome of acetaminophen-induced liver injury

178 rged in 2012 on the Arabian Peninsula with a clinical syndrome of acute respiratory infections, later

179 that are specific to biomarker-positive AD, clinical syndrome of AD, and/or pathologic AD brain, fin

180 tervention and prevention strategies for the clinical syndrome of AD.

181 large proteins that are responsible for the clinical syndrome of botulism.

182 There exists a clinical syndrome of BRCAness that includes serous histo

183 ions chronologically parallel the too-common clinical syndrome of delayed-onset paraplegia.

184 bnormalities explain the pathogenesis of the clinical syndrome of DOCK8 deficiency.

185 gland, whereas thyrotoxicosis refers to the clinical syndrome of excess circulating thyroid hormones

186 ic pulmonary fibrosis (IPF) is a progressive clinical syndrome of fatal outcome.

187 btle reductions of systolic function and the clinical syndrome of heart failure.

188 al parietal function as well as those of the clinical syndrome of hemispatial neglect.

189 on, consumption, and thrombocytopenia in the clinical syndrome of heparin-induced thrombocytopenia.

190 The clinical syndrome of HFpEF is heterogeneous and must be

191 mber of case and cohort reports describing a clinical syndrome of immune checkpoint inhibitor-associa

192 ystolic heart failure (heart failure) is the clinical syndrome of insufficient forward cardiac output

193 Critical limb ischemia (CLI) is a clinical syndrome of ischemic pain at rest or tissue los

194 ion findings increased the likelihood of the clinical syndrome of LSS (LR, 3.3; 95% CI, 2.7-4.0), whi

195 The diagnosis of the clinical syndrome of LSS requires the appropriate clinic

196 lower extremity pain, the likelihood of the clinical syndrome of LSS was increased for individuals o

197 ymptoms for increasing the likelihood of the clinical syndrome of LSS were having no pain when seated

198 and physical examination for diagnosing the clinical syndrome of LSS, using a reference standard of

199 CI, 1.4-13) increased the likelihood of the clinical syndrome of LSS.

200 The clinical syndrome of lumbar spinal stenosis (LSS) is a c

201 hin the belt has historically focused on the clinical syndrome of meningitis, the classic presentatio

202 ausative factors of bladder pain syndrome, a clinical syndrome of pelvic pain and urinary urgency/fre

203 antial increases in our understanding of the clinical syndrome of pneumonia and its aetiologies, its

204 (PBC) was first described in the 1950s as a clinical syndrome of progressive cholestatic liver disea

205 Malignant hyperthermia (MH) is a clinical syndrome of skeletal muscle that presents as a

206 The results suggest that the clinical syndrome of the behavioural variant of frontote

207 or autoimmune diseases can all result in the clinical syndrome of vasogenic edema in the central nerv

208 ing for children presenting with the typical clinical syndrome of viral upper respiratory infection p

209 e of Blood, Warkentin et al describe a novel clinical syndrome of warfarin-associated severe venous l

210 sis and meningitis and is important in other clinical syndromes of both humans and domestic animals;

211 l degeneration that encompasses the distinct clinical syndromes of frontotemporal dementia (FTD), pro

212 The clinical syndromes of frontotemporal dementia are clinic

213 nd neuropathological patterns of the diverse clinical syndromes of frontotemporal dementia.

214 bsequently discussed, while emphasising that clinical syndromes of FTD are dictated by the distributi

215 The clinical syndromes of hemophagocytic lymphohistiocytosis

216 ect the different pathophysiologies of these clinical syndromes of HF.

217 linum toxins, Clostridium botulinum produces clinical syndromes of infant botulism, wound botulism, a

218 We defined clinical syndromes of invasive GAS disease on the basis

219 on of iron-related traits and may also cause clinical syndromes of iron deficiency or excess.

220 In children presenting with different clinical syndromes of malaria, we assessed the relations

221 (SMA) are the most serious life-threatening clinical syndromes of Plasmodium falciparum infection in

222 The typical clinical syndromes of toxocariasis in humans are ocular

223 A clinical syndrome often has multiple possible genetic ca

224 cluster of illnesses represents an emerging clinical syndrome or syndromes.

225 ociated with this locus, the severity of the clinical syndrome, or both.

226 smal dyskinesia can be subdivided into three clinical syndromes: paroxysmal kinesigenic dyskinesia or

227 Observations: Asthma is a heterogeneous clinical syndrome primarily affecting the lower respirat

228 Clinical syndromes produced by WNV infection include asy

229 CBD was associated with 4 clinical syndromes: progressive nonfluent aphasia (n = 5

230 Trachoma presents distinct clinical syndromes ranging from mild and self-limiting t

231 of acute brain damage, and indicate how the clinical syndromes relate to emerging neurolinguistic, n

232 onal, which leads to several well-recognized clinical syndromes related to obesity (including type 2

233 The clinical syndrome resolved more rapidly among recipients

234 Heart failure (HF) is a complex clinical syndrome resulting from diverse primary and sec

235 Congestive heart failure is a complex clinical syndrome resulting from myocardial dysfunction

236 rly all children and was first linked to the clinical syndrome roseola infantum.

237 By comparison, defining the clinical syndrome(s) associated with CTE and the necessa

238 Major differences in clinical syndrome-specific patterns of AWaRe antibiotic

239 clearly demonstrated an overlap between the clinical syndromes subsumed under the term frontotempora

240 The former lead to clinical syndromes such as tuberous sclerosis, Peutz-Jeg

241 associated with invasive disease and severe clinical syndromes, such as meningitis and endocarditis.

242 One patient presented at age 65 years with a clinical syndrome suggestive of AD and showed evidence o

243 set of patients, most of whom do not have a clinical syndrome suggestive of esophageal spasm.

244 The distribution of clinical syndromes suggests that these patients have a l

245 nd other immune cells, resulting in a unique clinical syndrome termed CRAC channelopathy.

246 Although RSV causes a different clinical syndrome than influenza A virus, it is not read

247 Heart failure is a clinical syndrome that affects >6.5 million Americans, w

248 Analysis of infectious mononucleosis (IM), a clinical syndrome that can arise during primary EBV infe

249 gh Risk for psychosis (CHR-P) present with a clinical syndrome that can include social withdrawal and

250 HF is a complex clinical syndrome that can result in the impairment of e

251 Primary progressive aphasia is a clinical syndrome that encompasses three major phenotype

252 ailure with preserved ejection fraction is a clinical syndrome that has been associated with changes

253 Asthma is a heterogeneous clinical syndrome that includes subtypes of disease with

254 e from Cushing's original description of the clinical syndrome that now bears his name through to the

255 Heart failure is a complex clinical syndrome that occurs at the end stage of heart

256 y progressive aphasia is a neurodegenerative clinical syndrome that presents in adulthood with an iso

257 Male hypogonadism is a clinical syndrome that results from failure to produce p

258 We describe a novel clinical syndrome that results from homozygous loss of f

259 Heart failure (HF) is a clinical syndrome that usually develops in the elderly.

260 It is a commonly encountered clinical syndrome that, in its most severe form, increas

261 e liver failure is a potentially devastating clinical syndrome that, without liver transplantation (T

262 potential treatment options for the various clinical syndromes that are associated with CKD in hemat

263 tisystemic disorder characterized by complex clinical syndromes that are mechanistically poorly under

264 amyloid-beta and tau on PET and established clinical syndromes that are relevant to cognitive ageing

265 Cocaine use is associated with clinical syndromes that closely mimic other primary rheu

266 sed understanding of its precise role in the clinical syndromes that comprise IgG4-RSD may ultimately

267 n is associated with a variety of idiopathic clinical syndromes that may have infectious causes.

268 dvances in the understanding of neurological clinical syndromes that occur on exposure to high altitu

269 linking this large body of literature to the clinical syndromes that predispose humans to atheroscler

270 sistent with past reports for the respective clinical syndromes, these were centred on the left front

271 rrorism attacks are reviewed, along with the clinical syndromes they produce and their treatment.

272 microbial therapies to the task of ascribing clinical syndromes to etiologic microorganisms, an age-o

273 he extensive phenotypic heterogeneity of the clinical syndromes typically united by PTEN is reflected

274 ningeal carcinomatosis is a well-established clinical syndrome, virtually nothing is known about the

275 The clinical syndrome was otherwise indistinguishable betwee

276 His clinical syndrome was refractory to multiple immunosuppr

277 ervations of cardiogenic shock as a systemic clinical syndrome were first described in 1942.

278 e and those with MECP2 mutations without the clinical syndrome were recruited through the Rett Natura

279 Associations between genotypic networks and clinical syndromes were complex, showing multifinality a

280 The most common clinical syndromes were encephalitis (52%), acute dissem

281 Specific clinical syndromes were originally described in associat

282 The original descriptions of the associated clinical syndromes were phenotypically well circumscribe

283 It describes a clinical syndrome which can be caused by a number of dif

284 myelitis (LETM) is a frequently devastating clinical syndrome which has come into focus for its asso

285 ns, neurodegeneration and development of the clinical syndrome will be explored.

286 lities in ribosome biogenesis cause specific clinical syndromes will hopefully lead to novel therapeu

287 Acute liver failure (ALF) is a devastating clinical syndrome with a high mortality rate.

288 Pathological examination cannot classify the clinical syndrome with certainty; therefore, the neuropa

289 y to the conventional notion that svPPA is a clinical syndrome with few genetic risk factors, our ana

290 nction in response to hypertrophy is a major clinical syndrome with few therapeutic options.

291 iver failure (ALF) is a rare but challenging clinical syndrome with multiple causes; a specific etiol

292 ared for differential risk of developing the clinical syndrome with respect to host and microbial cha

293 the original reports that associated classic clinical syndromes with mitochondrial DNA (mtDNA) rearra

294 determination and differentiation can cause clinical syndromes with potential for the development of

295 It is not a unitary entity but a clinical syndrome, with variable deficits in social beha

296 low improved classification of heterogeneous clinical syndromes, with the ultimate goal of defining t

297 primary end point was the resolution of the clinical syndrome within 4 hours after administration of

298 on-specific F(ab')(2) antivenom resolved the clinical syndrome within 4 hours, reduced the need for c

299 d outcomes because sepsis is a heterogeneous clinical syndrome without a pathologic reference standar

300 ster in particular cases (phenotypic sets or clinical syndromes) without regard for their genetic bac