ライフサイエンスコーパス: clinicopathologic

1 We performed a clinicopathologic analysis of cases of pregnancy-associa

2 integrate multiple experimental models with clinicopathologic analysis of patient tumors to delineat

3 A) expression of GRPR, SSTR2, and CXCR4 with clinicopathologic and biologic factors, and with prognos

4 ast cancer tissues and correlated with known clinicopathologic and biologic factors, disease-free sur

5 Clinicopathologic and demographic variables were well ba

6 Clinicopathologic and follow-up data on 4661 patients tr

7 Complete clinicopathologic and follow-up data were available for

8 The diagnosis relies on characteristic clinicopathologic and immunopathologic features.

9 Clinicopathologic and laboratory investigations were per

10 ast cancers (2,608 carcinomas) to assess the clinicopathologic and molecular features and prognostic

11 breast cancer differs on the basis of tumor clinicopathologic and molecular features.

12 Correlated clinicopathologic and molecular genetic studies gave ris

13 ectively, and correlated those findings with clinicopathologic and outcome features.

14 Clinicopathologic and outcomes data were recorded, and d

15 The objective of this study is to conduct a clinicopathologic and polarized light microscopy (PLM) a

16 We describe the clinicopathologic and prognostic parameters of a series

17 COX-2, and VEGF status were correlated with clinicopathologic and survival data.

18 After adjusting for clinicopathologic and treatment characteristics, CR-EB a

19 Clinicopathologic and treatment data were reviewed for 9

20 Univariate analyses of clinicopathologic and treatment factors were performed,

21 Although demographic, clinicopathologic, and socioeconomic differences may aff

22 Associations between molecular, clinicopathologic, and survival data were analyzed.

23 ary to previous mastocytosis and shares more clinicopathologic aspects with systemic mastocytosis tha

24 However, its clinicopathologic associations have not been the focus o

25 A clinicopathologic case series describing the phenotype o

26 e-transplant patient who developed cutaneous clinicopathologic changes suggestive of CR.

27 Clinicopathologic characteristics and 3-year survival ra

28 A3B expression is associated with aggressive clinicopathologic characteristics and adverse outcomes a

29 ctional parameters and EBV DNA load with the clinicopathologic characteristics and clinical outcomes

30 Comparison of clinicopathologic characteristics and outcomes of 1958 p

31 expression, and their relationship with the clinicopathologic characteristics and overall survival (

32 trics of the T-cell receptor repertoire with clinicopathologic characteristics and patient outcomes.

33 the expression levels of KISS1 in PCas with clinicopathologic characteristics and to assess the biol

34 high expression of Bmi-1 and the associated clinicopathologic characteristics in esophageal adenocar

35 In this study, the clinicopathologic characteristics of allografts with dif

36 The clinicopathologic characteristics of malignant mesotheli

37 were more commonly associated with high-risk clinicopathologic characteristics of PTC than they were

38 independently of Breslow thickness and other clinicopathologic characteristics suggests that amelanot

39 Clinicopathologic characteristics were correlated with S

40 The association between tumor BF, clinicopathologic characteristics, and patients' overall

41 ata regarding the storage duration of PRBCs, clinicopathologic characteristics, and perioperative out

42 Sex differences in demographics, clinicopathologic characteristics, and postoperative out

43 After adjustment for patient demographic and clinicopathologic characteristics, increasing age was as

44 Demographic data, clinicopathologic characteristics, interval resection ra

45 ncer and high recurrence risk, as defined by clinicopathologic characteristics, may experience a 10%

46 ease and high recurrence risk, as defined by clinicopathologic characteristics, may experience improv

47 Clinicopathologic characteristics, operative details, an

48 The aim of this study was to explore the clinicopathologic characteristics, outcomes, and frequen

49 Clinicopathologic characteristics, overall survival (OS)

50 We collected clinicopathologic characteristics, patients' outcomes, a

51 Baseline clinicopathologic characteristics, preoperative laborato

52 In a multivariable model including clinicopathologic characteristics, relative to WT melano

53 Clinicopathologic characteristics, treatment regimens, a

54 When adding the immune module to clinicopathologic characteristics, we observed substanti

55 hed with 100 NO-VASC patients having similar clinicopathologic characteristics.

56 .05 for all), but there was no variation in clinicopathologic characteristics.

57 aled modules with and without adjustment for clinicopathologic characteristics.

58 ndently of intra-tumoral levels and baseline clinicopathologic characteristics.

59 orrelation between the PD-1/PD-L1 status and clinicopathologic characteristics.

60 to 14.97), which remained significant after clinicopathologic cofactor adjustments.

61 and genome-wide association study in a joint clinicopathologic cohort, including 725 deceased subject

62 ssociation studies were evaluated in a joint clinicopathologic cohort.

63 Clinicopathologic comparisons among luminal A and B subt

64 EoE is defined as an immune-mediated clinicopathologic condition characterized by oesophageal

65 s (EoE) is a chronic immune/antigen-mediated clinicopathologic condition that has become an increasin

66 y updated guidelines emphasize that EoE is a clinicopathologic condition.

67 ients with conventional HCC (cHCC) served as clinicopathologic controls.

68 oscopy (EVD) with derm dotting (DD) improves clinicopathologic correlation and the quality of diagnos

69 oscopy (EVD) with derm dotting (DD) improves clinicopathologic correlation and the quality of diagnos

70 Clinicopathologic correlation of consecutive group D eye

71 Clinicopathologic correlation of cutaneous lesions and g

72 This is an important clinicopathologic correlation of NV secondary to AMD in

73 Clinicopathologic correlation of punctate spots was perf

74 A high index of suspicion and careful clinicopathologic correlation on the part of transplant

75 Clinicopathologic correlation revealed increased stainin

76 mination, a notion that can now be tested in clinicopathologic correlation studies.

77 Clinicopathologic correlation was made by determining th

78 Cases with adequate material for clinicopathologic correlation were selected for further

79 Clinicopathologic correlation.

80 This study analyzed the clinicopathologic correlations and prognostic meaning of

81 Clinicopathologic correlations further identified associ

82 (HR; pT3/pT4) histopathologic features with clinicopathologic correlations.

83 on models were used to examine the effect of clinicopathologic covariates on discordance.

84 iable analysis adjusting for demographic and clinicopathologic covariates, PORT (hazard ratio, 0.80;

85 hat were well-characterized by gold standard clinicopathologic criteria (training set) and an indepen

86 The performance characteristics of clinicopathologic criteria for the identification of bia

87 g adults (AYAs) is not reliably predicted by clinicopathologic criteria.

88 Clinicopathologic data and outcomes for 378 patients tre

89 e Cancer Genome Atlas (TCGA) was queried for clinicopathologic data and syntaxin 6 expression.

90 Clinicopathologic data from a pancreatic cancer database

91 Clinicopathologic data from a population-based endometri

92 Clinicopathologic data including age, tumor size, histol

93 s, and integrating DNA and RNA analysis with clinicopathologic data may be a crucial step toward pers

94 ormat and analyzed the co-expression and the clinicopathologic data of ERG and IL-6 using immunohisto

95 Clinicopathologic data of PDAC patients surgically explo

96 Clinicopathologic data were collected for 546 patients w

97 Clinicopathologic data were retrospectively collected fo

98 py between 1997 and 2005 were identified and clinicopathologic data were used to determine the CPS+EG

99 Patient demographics and comorbidities, clinicopathologic data, and long-term outcomes among pat

100 Clinicopathologic data, including morphology of the panc

101 n appropriately integrated with high-quality clinicopathologic data.

102 le staining and correlated the read-out with clinicopathologic data.

103 mous disorder with limited epidemiologic and clinicopathologic data.

104 tprostatectomy, as well as within nearly all clinicopathologic, demographic, and treatment subgroups.

105 Reevaluation of clinicopathologic diagnoses and histopathologic findings

106 and molecular features of 33 patients with a clinicopathologic diagnosis of histiocytoid Sweet syndro

107 With EVD and DD, a specific clinicopathologic diagnosis was made in 27.7% of nevi co

108 sue lacks lymphatic vessels and analyzed the clinicopathologic differences between patients with acut

109 pared with NoLRT-NoDS cannot be explained by clinicopathologic differences, suggesting a potentially

110 Eosinophilic esophagitis is a clinicopathologic disease of increasing worldwide preval

111 phagitis (EoE) is a chronic antigen-mediated clinicopathologic disease of the esophagus characterized

112 Eosinophilic gastritis (EG) is a clinicopathologic disorder with marked gastric eosinophi

113 We suggest that this distinctive clinicopathologic entity be called pregnancy-associated

114 AITL is a rare clinicopathologic entity characterized by an aggressive

115 FSGS is a clinicopathologic entity characterized by nephrotic synd

116 ntified in the 1500s and defined as a unique clinicopathologic entity in 1809.

117 d agglutinin disease (CAD) is a well-defined clinicopathologic entity in which a bone marrow clonal B

118 Eosinophilic esophagitis (EoE) is a clinicopathologic entity of increasing worldwide prevale

119 Hairy cell leukemia (HCL) is a distinct clinicopathologic entity that responds well to purine an

120 cell lymphoma (ALCL) is a recently described clinicopathologic entity that usually presents as an eff

121 Atrial GCM represents a distinct clinicopathologic entity with a more favorable prognosis

122 Human gammadelta T-cell lymphoma is a rare clinicopathologic entity with aggressive course and poor

123 rt the distinction of NMZL as an independent clinicopathologic entity within the current lymphoma cla

124 r, PCNS PTLD appears to represent a distinct clinicopathologic entity within the PTLD spectrum that i

125 ithin hours of administration and suppresses clinicopathologic expression of experimental autoimmune

126 currence beyond that obtained from classical clinicopathologic factors (age, nodal status, tumor size

127 Traditional clinicopathologic factors affected survival constantly,

128 early breast cancer using readily available clinicopathologic factors and can aid individualized cli

129 Clinicopathologic factors and the performance of the Mem

130 s 52 months; P = 0.009) independent of other clinicopathologic factors and type of curative treatment

131 Clinicopathologic factors associated with LN positivity

132 ariable analyses were performed to determine clinicopathologic factors associated with LRR.

133 SLNB use was associated with clinicopathologic factors but also with health system fa

134 case-control matching analysis on prognostic clinicopathologic factors confirmed shorter OS (P < 0.00

135 Multivariate analysis of clinicopathologic factors for disease-specific survival

136 tudies of mostly larger tumors found that no clinicopathologic factors had significant prognostic val

137 ffect of ALDH1 expression was independent of clinicopathologic factors in the Yale cohort (risk ratio

138 astoma have been associated with a number of clinicopathologic factors including age and neurologic s

139 The impact of genetic, surgery-related, and clinicopathologic factors on OS and CS3 changed dramatic

140 ngraftment does not appear to correlate with clinicopathologic factors or patient survival.

141 on between the expression of these genes and clinicopathologic factors were also investigated.

142 ed for association with biological pathways, clinicopathologic factors, and copy number alterations.

143 The arms were equally balanced for clinicopathologic factors, except that there were more b

144 0.002) independent of KRAS status and other clinicopathologic factors.

145 opensity-score matching was performed for 12 clinicopathologic factors.

146 sTILs as a continuous variable adjusted for clinicopathologic factors.

147 well matched at baseline for demographic and clinicopathologic factors.

148 a chronic mature B-cell neoplasm with unique clinicopathologic features and an initial exquisite sens

149 Conclusion Clinicopathologic features and outcomes of children with

150 This study examines the clinicopathologic features and outcomes of IPNB.

151 The odds of TIL grades associated with clinicopathologic features and survival by TIL grade wer

152 rs was significantly associated with adverse clinicopathologic features and the absence of MSI.

153 ies have reported on the association between clinicopathologic features and thyroid dysfunction in pa

154 Cox proportional hazards models adjusted for clinicopathologic features and time to recurrence (data

155 The results were correlated with the clinicopathologic features and translocation statuses to

156 5hmC was strongly associated with aggressive clinicopathologic features and was an independent advers

157 pendent primary tumors on the basis of their clinicopathologic features are indeed independent occurr

158 exon 19 deletion mutations and show distinct clinicopathologic features associated with a significant

159 2 somatic mutations in breast cancer and the clinicopathologic features associated with LRRK2-mutated

160 Here, we compared endoscopic and clinicopathologic features between early proximal gastri

161 ed multifocal IPMNs were collected and their clinicopathologic features catalogued.

162 our different categories that were linked to clinicopathologic features for each patient.

163 The clinicopathologic features in our 3 cases best correspon

164 lointerstitial nephritis (IgG4-TIN), but its clinicopathologic features in the kidney are not well de

165 Clinicopathologic features included in some tests were e

166 We report the unique clinicopathologic features of a patient with systemic ma

167 MDS/MPNs have clinicopathologic features of both MDS and MPN diseases.

168 Unfamiliarity with the distinctive clinicopathologic features of EB pruriginosa led to an i

169 Here we describe clinicopathologic features of Ebola virus disease in pre

170 Overall, Tg(A116V) mice recapitulate many clinicopathologic features of GSS(A117V) that are distin

171 ed lncRNAs are significantly associated with clinicopathologic features of HCC.

172 phenotype, whereas BALB/c mice displayed the clinicopathologic features of HLH, as set forth in the H

173 nsity of monitoring, delays in diagnosis, or clinicopathologic features of late AR.

174 of human breast cancer and retain the major clinicopathologic features of primary tumors.

175 Recent studies have shed light on the clinicopathologic features of the histologic subtypes of

176 an important role of the cell-of-origin for clinicopathologic features of this disease.

177 The characteristic clinicopathologic features of this disorder allow differ

178 ing therapy empirically based on a patient's clinicopathologic features to using biomarker-driven tre

179 tations was assessed, and relationships with clinicopathologic features were examined.

180 It shares clinicopathologic features with C3 glomerulopathy, a com

181 We compared molecular and clinicopathologic features with disease-free survival.

182 he surgical resection specimens and compared clinicopathologic features with overall survival.

183 The association of clinicopathologic features with SLN status, lymph node r

184 d" cohort), and on the basis of (ii) classic clinicopathologic features, (iii) clinical subtypes, (iv

185 As by integrating diverse datasets including clinicopathologic features, affected cancer phenotypes,

186 On the basis of clinicopathologic features, an exercise-associated reduc

187 recombination-deficient (HRD) status on the clinicopathologic features, chemotherapy response, and s

188 sized prognostic impact and association with clinicopathologic features, including tumor size and inv

189 ll repertoire attributes are associated with clinicopathologic features, mutational and immune landsc

190 Clinicopathologic features, patient outcomes, GEP classi

191 cipher score, along with routinely available clinicopathologic features, to identify patients who wou

192 invasive ductal carcinomas (IDC) matched on clinicopathologic features.

193 types associated with outcome independent of clinicopathologic features.

194 ole, adding value to estimates with standard clinicopathologic features.

195 activity of primary uveal melanoma and other clinicopathologic features.

196 This study analyzes the clinicopathologic findings and their impact on outcome o

197 This case series details the clinicopathologic findings of patients with ABBA disease

198 Clinicopathologic findings, pretreatment leukocyte value

199 evels furthered classification and reflected clinicopathologic findings, while sequential tryptase me

200 review focuses on integrating findings from clinicopathologic, genetic, and epigenetic studies, whic

201 athogenic mechanisms underlying the observed clinicopathologic heterogeneity in PD are still not well

202 The clinicopathologic heterogeneity of myelodysplastic syndr

203 Despite their clinicopathologic heterogeneity, malignant germ cell tum

204 is a retrospective case series study of the clinicopathologic, immunohistochemical, and molecular fe

205 The panel had access to standard clinicopathologic information and baseline imaging findi

206 Data were collected regarding demographics, clinicopathologic information, tumor and genetic testing

207 lyses, which were corrected for conventional clinicopathologic markers, Mammostrat provided significa

208 was a significant improvement on either the clinicopathologic model or subtype model alone.

209 y predicts risk of RCC death beyond existing clinicopathologic models, particularly in low- and inter

210 Clinicopathologic, morbidity, and survival data were col

211 No clinicopathologic or treatment characteristics were asso

212 in terms of the distribution of patients by clinicopathologic or treatment-related (ADT use and leng

213 et of PC biomarkers that predict the risk of clinicopathologic outcomes in an ethnicity-dependent man

214 ty of PDAC and to determine the surgical and clinicopathologic outcomes of pancreatic resections afte

215 n in preoperative FNAB specimens with poorer clinicopathologic outcomes of PTC.

216 c background that defines PTC with the worst clinicopathologic outcomes, providing unique prognostic

217 ween ethnicity and biomarkers for predicting clinicopathologic outcomes.

218 evels significantly correlated with advanced clinicopathologic parameters and poor OS, with optimal c

219 Clinicopathologic parameters and TRG were correlated to

220 ed between 2000 to March 2014 to investigate clinicopathologic parameters associated with (18)F-FDG a

221 tly managed by observation because available clinicopathologic parameters cannot identify the 20% to

222 output and evaluated their association with clinicopathologic parameters in common human tumor types

223 The clinicopathologic parameters of the tumors were compleme

224 proportional hazards analysis adjusting for clinicopathologic parameters shows that the high-risk gr

225 PET scoring system was developed from these clinicopathologic parameters that allowed (18)F-FDG-avid

226 ved online risk calculator using alternative clinicopathologic parameters to more accurately predict

227 By using models incorporating clinicopathologic parameters to predict prostate cancer

228 ation between the target gene expression and clinicopathologic parameters was further analyzed.

229 of MT1-MMP and EMT-associated proteins with clinicopathologic parameters were analyzed.

230 nly requires the input of 6 widely available clinicopathologic parameters.

231 cinoma after preoperative CRT independent of clinicopathologic parameters.

232 Results were correlated with clinicopathologic parameters.

233 (SN) metastasis varies according to several clinicopathologic parameters.

234 Despite this, svPPA's relatively homogenous clinicopathologic phenotype makes it an ideal investigat

235 Clinicopathologic predictors and melanoma-specific survi

236 Clinicopathologic predictors of EBL were identified usin

237 Clinicopathologic predictors of local and locoregional d

238 Y OF BACKGROUND DATA: Despite well-described clinicopathologic predictors of posttransplant HCC recur

239 This report increases the range of clinicopathologic presentations of C9ORF72 expanded hexa

240 Clinicopathologic profiles between resection and transpl

241 ltivariable analyses accounting for standard clinicopathologic prognostic factors (10-year biochemica

242 ell-validated genomic assays such as RS with clinicopathologic prognostic factors for chemotherapy in

243 in BLBC (P = 0.0001), independently of other clinicopathologic prognostic factors including lymph nod

244 factor used in the stratified randomization, clinicopathologic prognostic factors, and other factors

245 ined significant when adjusted for all other clinicopathologic prognostic factors.

246 y and supports the integration of sTILs in a clinicopathologic prognostic model for patients with TNB

247 efine a distinct genetic subtype that shares clinicopathologic properties with clinically confirmed s

248 ignaling components in primary HCC and their clinicopathologic relevance and significance was evaluat

249 An FFGED achieved clinicopathologic remission in 54% of adult patients wit

250 enty-eight of the 52 patients (54%) achieved clinicopathologic remission on the FFGED and 6 of the 19

251 MT resolved with EoE treatments that induced clinicopathologic remission with reduced eosinophil coun

252 fects regression analyses adjusted for known clinicopathologic risk factors (P < .001 for all end poi

253 azard ratios (HRs), adjusted for significant clinicopathologic risk factors, were used to determine t

254 idualized approach to SNB that considers all clinicopathologic risk factors.

255 gram by incorporating the signature with the clinicopathologic risk factors.

256 patients with BRAF V600E was independent of clinicopathologic risk factors.

257 endent c-indices were constructed to compare clinicopathologic risk models with the clinical-genomic

258 es useful additional information to existing clinicopathologic scoring systems of prostate cancer and

259 It will be important to perform a larger clinicopathologic series to aid our anatomic interpretat

260 were developed to assess the association of clinicopathologic (sex, age, race/ethnicity, comorbiditi

261 are emerging targets in oncology, but their clinicopathologic significance in thyroid cancer is uncl

262 We sought to determine the frequency and clinicopathologic significance of ATR mutations in patie

263 The clinicopathologic significance of mismatch repair (MMR)

264 The aim of this study was to investigate the clinicopathologic significance of Sam68 expression and i

265 peats (EMAST), but little is known about the clinicopathologic significance of these features.

266 the innervation of esophageal cancer and its clinicopathologic significance remain unclear.

267 e reverse transcriptase PCR to determine its clinicopathologic significance.

268 stical analyses were applied to evaluate the clinicopathologic significance.

269 e, for which prognosis has been relegated to clinicopathologic staging for decades.

270 This large, prospective, clinicopathologic study enrolled patients who filled out

271 Associations with clinicopathologic traits and patient outcomes were exami

272 6.1%, P < 0.001), even after controlling for clinicopathologic variables (hazard ratio [HR] = 2.33, P

273 cohorts (n = 315) matching patients based on clinicopathologic variables (luminal B 10-year metastasi

274 hese molecular variables in combination with clinicopathologic variables (patient age, Breslow depth,

275 ly greater than a model that only considered clinicopathologic variables and also performed well in t

276 Clinicopathologic variables and prognostic biomarkers SM

277 ge-cell/anaplastic (LC/A) phenotype were the clinicopathologic variables associated with poor progres

278 omic classifier in combination with standard clinicopathologic variables can generate a simple-to-use

279 adhesion-linked gene expression variables to clinicopathologic variables improves the identification

280 Clinicopathologic variables included patient age and sex

281 Comparison of microRNA microarray data with clinicopathologic variables revealed a negative correlat

282 ature-derived relative risk ratios for seven clinicopathologic variables to predict ipsilateral breas

283 The DCIS nomogram integrates 10 clinicopathologic variables to provide an individualized

284 Clinicopathologic variables were analyzed for associatio

285 The relationships between MMR classes and clinicopathologic variables were assessed using continge

286 Clinicopathologic variables were compared between tumors

287 mount pathologic analysis was performed, and clinicopathologic variables were correlated with disease

288 Clinicopathologic variables were tested using competing

289 , associations with biological pathways, and clinicopathologic variables were the main outcomes.

290 The relation between the LMR, clinicopathologic variables, and other biomarkers were a

291 luated the association of sociodemographics, clinicopathologic variables, and SHS with either smoking

292 tions between genotypes, protein expression, clinicopathologic variables, and survival was assessed.

293 is of individual patient data, adjusting for clinicopathologic variables, Decipher remained a statist

294 The relationships between mutations and clinicopathologic variables, including overall and disea

295 rial cancers to assess the relationship with clinicopathologic variables, patient survival and associ

296 nd lymph node metastasis, but not with other clinicopathologic variables.

297 oor clinical outcome is independent of these clinicopathologic variables.

298 dditional prognostic information to standard clinicopathologic variables.

299 large geographic areas, and lacked detailed clinicopathologic variables.

300 ures of PSP indicate that there are distinct clinicopathologic variants of PSP.