ライフサイエンスコーパス: clock-controlled gene

1 en by rhythmic transcriptional activation of clock-controlled genes.

2 of day and night through complex networks of clock-controlled genes.

3 no acid-rich basic leucine zipper (PAR-bZip) clock-controlled genes.

4 re clock genes and an ever-expanding list of clock-controlled genes.

5 ly suppress their own expression and that of clock-controlled genes.

6 downregulation of circadian transcription of clock-controlled genes.

7 ertheless, we were able to identify four new clock-controlled genes.

8 NPAS2 to activate transcription of clock and clock-controlled genes.

9 through temporal control of tissue-specific clock-controlled genes.

10 escent recorder hooked up to a promoter on a clock controlled gene-2 (ccg-2).

11 LOCK-BMAL1 transactivation of clock gene and clock-controlled gene activity.

12 tions of D4Rs, the clock gene Npas2, and the clock-controlled gene adenylyl cyclase 1 (Adcy1) in a su

13 he levels of many genes and proteins, termed clock controlled genes and proteins (CCGs/CCPs), to impa

14 In addition, rrp44 is a clock-controlled gene and a direct target of the WHITE C

15 To identify novel clock-controlled genes and to examine these models, we h

16 rcadian rhythms of frq RNA, FRQ protein, and clock-controlled genes are abolished in the CKII mutant.

17 Clock-controlled genes are also generated by the central

18 ies in mice have demonstrated that circadian clock-controlled genes are vital for protein homeostasis

19 clock genes mPer1, mPer2, and mCry1 and the clock-controlled gene arginine vasopressin (AVP) in the

20 We study the dynamics of a circadian clock-controlled gene at the individual cell level in An

21 are endogenous transcriptional repressors of clock-controlled genes, but again CRY1 was preeminent.

22 clock genes (CLOCK, BMAL1, and Period1) and clock-controlled genes (c-Myc, NR1D1, and CDKN1A), with

23 into how the variation in the percentage of clock-controlled genes can be generated in mouse tissues

24 ents of the clock, CLOCK-BMAL1, on mPer1 and clock-controlled gene (CCG) activity.

25 ps among rhythmic chromatin modifications at clock-controlled genes (ccg) revealing circadian control

26 ified for 23 enhancer trap lines to identify clock-controlled genes (CCG-ETs).

27 escribe the sequence and analysis of a novel clock-controlled gene, ccg-7, showing similarity to glyc

28 ) that in turn coordinates the expression of clock-controlled genes (CCGs) directing circadian progra

29 hanisms of circadian gene expression of core clock-controlled genes (CCGs) may help better understand

30 Studies of clock-controlled genes (CCGs) reveal a complex pattern o

31 Indeed, the isolation of clock-controlled genes (ccgs) was pioneered in Neurospor

32 rs regulate the daily rhythmic expression of clock-controlled genes (ccgs).

33 We identified 145 clock-controlled genes (ccgs).

34 in differential screens to identify six new clock-controlled genes (ccgs).

35 Dysregulated clock and clock-controlled gene expression occur in multiple tissu

36 roRNAs (miRNAs) contribute to core clock and clock-controlled gene expression using mice in which miR

37 cillations in nucleosome occupancy influence clock-controlled gene expression, suggesting a role for

38 eral feedback linking rhythmic metabolism to clock-controlled gene expression.

39 s the waveform of rhythmic expression of two clock-controlled genes, implicating FKF1 in modulating t

40 dent chromatin remodeling on the promoter of clock controlled genes in the vasculature permits the ma

41 an rhythm and decreases the transcription of clock-controlled genes in a concentration-dependent mann

42 st functions of circadian rhythms regulating clock-controlled genes in both mouse and human enteroids

43 al expression of core clock genes as well as clock-controlled genes in both sites.

44 s required for transcriptional remodeling of clock-controlled genes in cardiac myocytes in response t

45 on studies, which have uncovered hundreds of clock-controlled genes in cyanobacteria, fungi, plants,

46 we investigated the expression of clock and clock-controlled genes in multiple tissues (suprachiasma

47 ith the core clock factors for expression of clock-controlled genes in skeletal muscle.

48 plitude as well as synergistic regulation of clock-controlled genes in skeletal muscle.

49 The CLOCK-BMAL1 complex activates clock-controlled genes, including cryptochromes (Crys),

50 RT1 coordinates the circadian oscillation of clock-controlled genes, including genes that encode enzy

51 ranscriptionally regulates expression of the clock-controlled genes, including the well-characterized

52 fect the expression of hundreds of circadian-clock-controlled genes, many of which are involved in ke

53 rns rhythmic WCC binding to the promoters of clock-controlled genes mediating the essential first ste

54 Significantly, circadian and clock-controlled gene mutations have recently been ident

55 T differentially orchestrates oscillation of clock-controlled gene networks and the diurnality of met

56 pletion of Bmal1 decreased the expression of clock-controlled genes Per2 and Tcap, as well as Sik1, a

57 s, but found that peak expression of several clock-controlled genes (PER3, NR1D1, NR1D2, CRY1, CRY2,

58 The identification of MyoD as a clock-controlled gene provides a mechanism by which the

59 We identified a novel clock-controlled gene (quasimodo) that encodes a light-r

60 A screen for clock-controlled genes recovered vrille (vri), a transcr

61 Sik1 represents a novel clock-controlled gene that coordinates myocyte growth wi

62 Prokineticin 2 (PK2), a clock-controlled gene that encodes a secreted protein, h

63 th these functions, the liver expresses many clock-controlled genes that are required for these proce

64 affects the circadian expression of all four clock-controlled genes that we examined.

65 number of genes with circadian rhythmicity (clock-controlled genes), there was only about 10% overla

66 ression and amplitude of the muscle specific clock-controlled gene, Titin-cap (Tcap).

67 t allow the phase of peak expression for one clock-controlled gene to alter, relative to other genes

68 L), that lengthen the free-running period of clock-controlled gene transcription and cell expansion,

69 d prevented phenylephrine-induced changes in clock-controlled gene transcription.

70 dinates myocyte growth with hypertrophic and clock-controlled gene transcription.

71 Recent advances in identifying novel clock-controlled genes using rodent and cellular models

72 ption of core circadian genes and downstream clock-controlled genes was observed in constant darkness

73 hortened the periods of four known circadian clock-controlled genes with different phase angles, demo