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1 our institution, she had a generalized tonic-clonic seizure.
2 he experienced a witnessed generalized tonic-clonic seizure.
3 to first seizure of any type and first tonic-clonic seizure.
4 urring during, or immediately after, a tonic-clonic seizure.
5 f eclampsia, as defined by a witnessed tonic-clonic seizure.
6 notype consisting of 3/sec absence and tonic-clonic seizures.
7  in focal-to-bilateral and generalized tonic-clonic seizures.
8 ve in managing partial and generalized tonic-clonic seizures.
9 c, myoclonic, absence, and generalised tonic-clonic seizures.
10 ines displayed spontaneous generalized tonic-clonic seizures.
11 arrays during three focal to bilateral tonic-clonic seizures.
12 ife and overt myoclonic or generalised tonic-clonic seizures.
13 in patients who experience generalized tonic-clonic seizures.
14 generalized myoclonic and/or bilateral tonic-clonic seizures.
15 y active during periods of generalized tonic-clonic seizures.
16 nic seizures and relatively infrequent tonic-clonic seizures.
17 approximately 30 suspected generalized tonic-clonic seizures.
18 rogressively severe myoclonus and rare tonic-clonic seizures.
19 rred immediately following generalized tonic-clonic seizures.
20 d with the tonic phases of generalized tonic-clonic seizures.
21 ures and to pentylenetetrazole induced tonic-clonic seizures.
22 le childhood epilepsy with generalized tonic-clonic seizures.
23 ly involved in secondarily generalized tonic-clonic seizures.
24 ions and for impaired consciousness in tonic-clonic seizures.
25 seizures, required ASIC1a to interrupt tonic-clonic seizures.
26 ced threshold to electrically evoked minimal clonic seizures.
27 used by kainic acid, in the absence of tonic-clonic seizures.
28 havioral endpoints of epileptogenesis, tonic-clonic seizures.
29 t week 3 to 4 of life from generalized tonic-clonic seizures.
30 nique capacity to initiate generalized tonic-clonic seizures.
31  at a mean age of 42 days from massive tonic-clonic seizures.
32 ffective control of focal to bilateral tonic-clonic seizures.
33  seizure (1.3 [1.1 to 1.6]), and first tonic-clonic seizure (1.5 [1.2 to 1.8]).
34 onsive to fenfluramine was generalized tonic-clonic seizure (120 of 263 [46%]), with a decrease in fr
35 rile seizures (7/29, 25%), generalized tonic-clonic seizures (5/29, 17%), and focal-onset seizures (3
36                        10 suppressed minimal clonic seizures (6 Hz mouse model) without typical rotar
37 th new-onset seizure was a generalized tonic-clonic seizure (72 [33%]).
38  myoclonus (all patients), generalized tonic-clonic seizures (all patients) and complex partial seizu
39 epilepsy and epilepsy with generalized tonic-clonic seizures alone.
40  prefrontal cortex are associated with tonic-clonic seizures and a normal survival rate.
41 res, and 1 had 4 witnessed generalized tonic-clonic seizures and approximately 30 suspected generaliz
42 ers manifesting with action myoclonus, tonic-clonic seizures and ataxia.
43 poral lobe epilepsy, and epilepsy with tonic-clonic seizures and cognitive regression.
44 timated lifetime number of generalized tonic-clonic seizures and functional cluster membership was as
45                 Moreover, incidence of tonic clonic seizures and hindlimb extension were reduced in w
46 epilepsy with early onset, generalized tonic-clonic seizures and juvenile lethality by 3 weeks of age
47 hildhood absence epilepsy, generalized tonic clonic seizures and the epileptic encephalopathy, Dravet
48  frequent myoclonic jerks, generalized tonic-clonic seizures and, less commonly, absences.
49 its acoustically triggered generalized tonic-clonic seizures, and often times the EEG, recorded with
50 sease patients present with myoclonus, tonic-clonic seizures, and progressive declines in cognitive a
51 died prematurely following generalized tonic-clonic seizures, and they were equally susceptible to th
52                            Generalized tonic-clonic seizures are among the most dramatic physiologica
53                     Focal to bilateral tonic-clonic seizures are associated with lower quality of lif
54 mes in which generalized myoclonic and tonic-clonic seizures are expressed.
55                            Generalised tonic-clonic seizures are the greatest risk factor for SUDEP;
56 s of GABA metabolism, and one in which tonic-clonic seizures associate with increased central nervous
57 n to sound stimuli-induced generalized tonic-clonic seizures (audiogenic reflex seizures) and is a va
58 , neurological insult, total number of tonic-clonic seizures before randomisation, seizure type and t
59 7-11.1], history of focal to bilateral tonic-clonic seizures before surgery (aHR 1.6, 95% CI 0.9-2.8)
60 lete and reversible blockade of only the F&F clonic seizure behavior was induced by AP7 (1 and 7.5 nm
61 ifference in occurrence of generalized tonic-clonic seizures between groups was 0.3% (95% CI = +/-8.6
62 caused low seizure threshold, sporadic tonic-clonic seizures, brain enlargement and ectopic neurons i
63 , and all homozygotes exhibited lethal tonic-clonic seizures by mid-third week.
64 age between oral automatisms and generalized clonic seizures, by measuring changes in mRNA expression
65 g the networks involved in generalized tonic-clonic seizures can provide insights into mechanisms of
66 ed early onset spontaneous generalized tonic-clonic seizures concurrent with a significant reduction
67                                        Tonic-clonic seizures developed spontaneously after 5 months o
68                 Only 17 of these had a tonic-clonic seizure during follow-up.
69 e with EEG abnormality were at risk of tonic-clonic seizures during follow-up compared with 16% of th
70 ining three had infrequent generalized tonic-clonic seizures during nocturnal sleep.
71 ted with afebrile focal or generalized tonic-clonic seizures during the first to second year of life;
72 y (JAE), and epilepsy with generalized tonic clonic seizures (EGTCS).
73 t paradigm, pentylenetetrazole-induced tonic-clonic seizures, exclude the possibility that the geneti
74                            Fewer generalized clonic seizures failed to reliably produce changes in se
75 ocal epilepsy, with focal to bilateral tonic-clonic seizures (FBTCS+) a more severe form of the disor
76 on phase of the experiment, only generalized clonic seizures ("forebrain seizures") were expressed.
77 aired awareness, or focal to bilateral tonic-clonic seizures) from baseline analysed in the modified
78 (JME), one predisposing to generalized tonic-clonic seizures (GTCS) and a second to myoclonic seizure
79 gh risk of SUDEP (with >=1 generalised tonic-clonic seizure [GTCS] per year), low risk of SUDEP (no h
80 zed with the algorithm: 25 generalized tonic-clonic seizures (GTCSs) from 11 patients, and 19 episode
81 partial seizures (PSZ) and generalized tonic-clonic seizures (GTSZ) with and without structural heart
82 ltered if (1) a minimum of eight generalized clonic seizures had been expressed, and (2) a minimum of
83 ncreased latencies to forelimb clonus, tonic clonic seizures, hindlimb extension, and death compared
84 ents with different focal to bilateral tonic-clonic seizure histories.
85 " (HP: 0011172; p = 2.1 x 10(-5)) and "focal clonic seizures" (HP: 0002266; p = 8.9 x 10(-6)), STXBP1
86 le childhood epilepsy with generalized tonic-clonic seizures (ICEGTC), which bears similarity to SMEI
87 ion, decreased spontaneous generalized tonic-clonic seizures in a model of temporal lobe epilepsy, an
88 ic hyperactivity immediately following tonic-clonic seizures in DS mice, which leads to lethal bradyc
89 astic behaviors and eventually induces tonic-clonic seizures in rodents.
90 ty, occurrence of tonic-clonic and non-tonic-clonic seizures in the 3 months before pregnancy, previo
91 miR-335-5p increased susceptibility to tonic-clonic seizures in the pentylenetetrazol seizure model,
92 seizures are at low risk of subsequent tonic-clonic seizures in the period of time to which therapeut
93 ivation after focal motor to bilateral tonic-clonic seizures in the striatum, globus pallidus externu
94 fects of treatment on the frequency of tonic-clonic seizures in those patients with such pre-randomis
95 sitive histories of focal to bilateral tonic-clonic seizures, including both remote (none for >1 year
96 pothalamic brain sites following generalized clonic seizures induced by kainic acid.
97 greater latency and lower incidence of tonic-clonic seizures induced by pentylenetetrazol (PTZ; 70 mg
98 ent episodes of unprovoked generalized tonic-clonic seizures lasting 2-3 minutes that spontaneously r
99 ent episodes of unprovoked generalized tonic-clonic seizures lasting 2-3 minutes that spontaneously r
100 aired awareness and focal to bilateral tonic-clonic seizures may also help us to understand their dif
101  SPECT from 59 secondarily generalized tonic-clonic seizures obtained during epilepsy surgery evaluat
102  (JME), epilepsy with only generalized tonic-clonic seizures occurring either randomly during the day
103 e absence epilepsy, five patients with tonic-clonic seizures on awakening and 30 control subjects had
104 epsy and two out of five patients with tonic-clonic seizures on awakening, but in none of the 30 cont
105 le absence epilepsy, and epilepsy with tonic clonic seizures only under the sole heading of idiopathi
106 can provide notification of an ongoing tonic-clonic seizure, or peace of mind in the absence of notif
107                    Because generalised tonic-clonic seizures precede most cases of SUDEP, patients mu
108 onsciousness during focal to bilateral tonic-clonic seizures remain unclear.
109          Daily flurothyl-induced generalized clonic seizures resulted in a progressive decrease in bo
110 MP6s but not GCaMP6f in the DG induces tonic-clonic seizures several weeks after viral injection.
111  six patients experiencing generalized tonic-clonic seizures showed marked improvement, three showed
112 impaired awareness seizures (FIAS) and tonic-clonic seizures (TCS) over 6.5 months.
113 rter latencies to onset of generalized tonic-clonic seizures than controls.
114 used in the MESS study are greater for tonic-clonic seizures than they are for partial seizures.
115 fractory partial-onset and generalized tonic-clonic seizures that acts as a selective negative allost
116 h the remaining 7-12% comprising generalized clonic seizures that transition into brainstem seizures.
117 icate that the higher the frequency of tonic-clonic seizures, the higher the risk of SUDEP; furthermo
118 ere was an increase in the flurothyl-induced clonic seizure threshold (anticonvulsant effect) in the
119 ere was an increase in the flurothyl-induced clonic seizure threshold after an E injection alone whil
120 ction alone while there was a reduced tonic--clonic seizure threshold in the presence of both hormone
121 ine, and he continued to have frequent tonic-clonic seizures throughout his life.
122 reasing latency of pilocarpine-induced tonic-clonic seizures upon in vivo coelenterazine administrati
123 in is unusually sensitive to recurrent tonic-clonic seizures upon routine handling and to seizures in
124 ctrical stimulation until the first forelimb clonic seizure was induced.
125 othyl and the threshold for clonic and tonic-clonic seizures was determined.
126 igated by metabolic sources of carbon; tonic-clonic seizures were also suppressed by alpha-amino-3-hy
127 impaired awareness, focal to bilateral tonic-clonic seizures were characterized by deeper loss of con
128 holds for flurothyl-induced clonic and tonic-clonic seizures were determined.
129        Preoperative focal to bilateral tonic-clonic seizures were independently associated with seizu
130 es conferring a low threshold to ECT minimal clonic seizures were mapped to the telomeric region of m
131                                        Tonic-clonic seizures were observed in HAGS animals, while LAG
132             Wildtypes developed severe tonic-clonic seizures, whereas knockouts had mild seizure acti
133  of aged apoE4 TR mice had more severe tonic-clonic seizures which occasionally progressed to tonic e
134 ice) exhibited spontaneous generalized tonic-clonic seizures (which occurred in the absence of cardia
135                    All had generalized tonic-clonic seizures with onset associated with fever, consis
136  normal early development, generalized tonic-clonic seizures with onset at 5-10 years of age, and pro
137 zures recorded, the majority are generalized clonic seizures, with the remaining 7-12% comprising gen
138 e of the normoglycemic rats, developed tonic-clonic seizures within 12h after ischemia.

 
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