ライフサイエンスコーパス: cluster

1 controlling for sex, race, comorbidity, and cluster.

2 NA-PKcs and its phosphorylation at the T2609 cluster.

3 ique hexanuclear iron cofactor denoted the H-cluster.

4 a coli binds an all-Cys-coordinated [2Fe-2S] cluster.

5 ly by the movement of chromosomes to a dense cluster.

6 t through regulation of the miR-424(322)/503 cluster.

7 patient-to-patient transmission in the later cluster.

8 from human embryonic cell-derived beta-cell clusters.

9 oming from the 8-connected hexanuclear Zr(6) clusters.

10 ailed guidance on high-performance computing clusters.

11 mall molecules inspired by biosynthetic gene clusters.

12 method for simulating multivariate Gaussian clusters.

13 DNA looping occurs at Top2 clusters.

14 ing RE(iii)-ions, RE(iii)-chains, or RE(iii)-clusters.

15 on algorithms produce a fixed number of cell clusters.

16 were comparable to the previously identified clusters.

17 ustion of available valencies within smaller clusters.

18 ushes collapse and Ki-67 promotes chromosome clustering.

19 ts (BSP), multivariate analyses and Bayesian clustering.

20 omponent analysis, k-means, and hierarchical clustering.

21 hylogenetic analysis was performed to detect clustering.

22 ted using the WB without ventricles (average cluster, 21.6% +/- 0.1%).

23 e, referred to as ECM3 (Extracellular Matrix Cluster 3), indicated poorer survival in patients with g

24 analysis identified 4 serum biomarker-based clusters, 3 of which (clusters B, C, and D) were compara

25 lusters [36 008 pregnancies]) or control (22 clusters [33 322 pregnancies]) groups.

26 ) were randomly assigned to intervention (22 clusters [36 008 pregnancies]) or control (22 clusters [

27 Overall, 44 clusters (69 330 pregnant women) were randomly assigned

28 cies) and prolific secondary metabolite gene clusters (73 per species) in section Flavi.

29 t induce seroprotective antibodies to 2010.1 cluster A(H3N2)v viruses in young children, suggesting t

30 insulin resistance and insulin secretion) to cluster adult-onset diabetes patients into five subtypes

31 A clustering algorithm using a threshold of 400 allelic di

32 This cluster also shows strong homology to a putative ET clus

33 Cluster analysis identified 4 serum biomarker-based clus

34 Cluster analysis of this large cohort of eyes identified

35 We used cluster analysis to group patients by the dose, recency,

36 Hierarchical cluster analysis was used to determine subgroups of part

37 Combining high-content imaging and cluster analysis, we show that in male rats SCI decrease

38 iminant analysis (OPLS-DA), and hierarchical cluster analysis.

39 Clustering analysis of the copy number profiles revealed

40 ells were considerably more heterogeneous by clustering analysis than the epithelial cells.

41 Cluster Of Clusters Analysis (COCA) is one such approach that has b

42 B readily associates with PM via a polybasic cluster and a Ca(2+)-binding loop.

43 the evolutionary events leading to this gene cluster and found that its phylogenetic distribution cor

44 one-pathway genes shared between a microglia cluster and infiltrating macrophages.

45 olutionary success for an emerging antigenic cluster and quantified fundamental trade-offs in our abi

46 sity prevalence in the country, adjusted for cluster and sample weight.

47 of CntB and also of the Rieske-type [2Fe-2S] cluster and the mononuclear [Fe] center of CntA were ide

48 The clustered and variable O-glycans make the IgA1 glycomic

49 Once adjusting for clustering and age, the difference in decline between th

50 temporally coincides with mitochondrial BAX clustering and cytochrome c release.

51 t transformation, a data-driven hierarchical clustering and dimension reduction technique.

52 d glaucoma dashboard." We used density-based clustering and the VF decomposition method called "arche

53 However, widely used clustering and visualization algorithms produce a fixed

54 common populations that outperforms popular clustering and visualization algorithms, as demonstrated

55 lly eligible people, 637 from 5 intervention clusters and 1,097 from 10 UC clusters were recruited be

56 xample of mutual stabilization between metal clusters and a self-assembled metal-organic cage.

57 We found larger nesting clusters and decreased attacks on outgroup competitors i

58 nd states in the [Ni(4)(NP(t)Bu(3))(4)](+/0) clusters and fully delocalized, spin-correlated electron

59 ghest among all RE MOFs based on nonanuclear clusters and some of the highest in the entire RE family

60 ubtype categorization to define phylogenetic clusters and the development of an SNP cut-off for trans

61 anding of both the activation of silent gene clusters and the ecological function of the produced com

62 te varying estimates regarding the number of clusters and the single-cell level cluster assignments.

63 lp to understand the link between individual clusters and wider community spread.

64 torization, quantile normalization and joint clustering, and visualization.

65 present SVXplorer, which uses a graph-based clustering approach streamlined by the integration of no

66 Consequently, clusters are permanently switched on by neuronal spiking

67 Globular clusters are some of the oldest bound stellar structures

68 Galaxy clusters are the most massive virialized structures in t

69 d miR-20a, which all belong to the miR-17~92 cluster, are upregulated during wound repair.

70 g the study contributed to the prediction of cluster assignment most accurately (84% in out-of-sample

71 number of clusters and the single-cell level cluster assignments.

72 Principal component analysis revealed gene clusters associated with the observed behavioral respons

73 analysis revealed that lamprey GHR and PRLR cluster at the base of gnathostome GHR and PRLR clades,

74 FLAPS configurations were substantially more clustered at the scales relevant for the implemented mod

75 Coastal sites, clustered at the water's edge, are already experiencing

76 serum biomarker-based clusters, 3 of which (clusters B, C, and D) were comparable to the previously

77 dergoes reduction due to the closo-C(2)B(10) cluster backbone, which is prone to accept up to two ele

78 ubstitution, 11 doublet-base-substitution, 4 clustered-base-substitution and 17 small insertion-and-d

79 y, the data from the transfer of 12 nif gene clusters between 15 diverse species (including Escherich

80 Biosynthetic gene clusters (BGCs) are operonic sets of microbial genes tha

81 in model membranes PIP2 can form nanoscopic clusters bridged by multivalent cations.

82 ecific gamma-c clade, within which sequences cluster by species, suggesting frequent duplication and/

83 ates; PFGE patterns did not reliably predict clustering by cgMLST analysis.

84 rect oxidation of a B-B bond between a boron cluster cage and an exopolyhedral boron-based substituen

85 led characterization of two late-acting Fe-S cluster-carrier proteins from Arabidopsis thaliana, NFU4

86 Cyclic coordination clusters (CCCs) are proving to provide an extra dimensio

87 (theta) clusters had deteriorated with p < p(Cluster), chosen empirically to give 95% specificity bas

88 same finger (or combination of fingers) may cluster closely together, while neurons that control dif

89 response showed converging IGHV3-driven BCR clusters closely associated with SARS-CoV-2 antibodies.

90 structure (degree, eigenvector, betweenness, clustering coefficient).

91 n gray matter volumes, degree, strength, and clustering coefficient.

92 esulting in increased dissemination of small clusters compared to untreated control MCAs.

93 Clustering concordance analyses demonstrated some differ

94 DSG3-CAART IFN-gamma secretion and homotypic clustering, consistent with an activated phenotype.

95 orm the cage-opened dianionic nido-C(2)B(10) cluster core.

96 Moreover, the quantitative quality of these clusters correlated with the identification of functiona

97 cortical neurons have revealed more than 100 clusters corresponding to putative cell types.

98 uctive number, R(e) of New Zealand's largest cluster decreased from 7 to 0.2 within the first week of

99 In enhancer cluster-deficient animals, Nppa was induced but remained

100 criteria based on comprehensive overlapping clusters detected deterioration significantly sooner.

101 t matrix-free divisive hierarchical spectral clustering different from prevalent single-resolution cl

102 or and a co-membership matrix to categorize (cluster) differentially expressed genes based on their m

103 nd verified the [2Fe-2S]-containing GLRX5 as cluster donor.

104 lyses were adjusted for confounding by time, cluster effects, and patient-level and hospital-level ch

105 f the predicted proteins of acrophiarin gene cluster exhibited higher similarity to the predicted pro

106 As a cluster expands, the predictions improve while the lead-

107 orithmic clustering methods that are able to cluster features in a fast and reliable way are necessar

108 The biosynthetic gene cluster for FA has been identified, but the biosynthetic

109 NAb responses differed significantly between clusters for 3 of 18 pseudoviruses examined (P < .05), b

110 he understanding of the necessity of epitope clusters for effective mAb recognition.

111 stage), macroscopic interconnected aggregate clusters form, grow, fuse, and evolve via internal rearr

112 s such as amino acid biogenesis, iron-sulfur cluster formation, and redox homeostasis.

113 Moreover, we observed that cluster-forming proteins significantly compact the DNA c

114 sis than to those of the echinocandin B gene cluster from A. pachycristatus.

115 ly reduces metastatic outgrowth and switches clusters from a proliferative to a collective migratory

116 Moreover, water clusters from the hydrated protein films have been obser

117 cs tasks such as gene prioritization, sample clustering, gene set analysis, and expression signature

118 ced by transpositional insertions into piRNA clusters, genomic regions encoding the Piwi-interacting

119 conclusion, unvaccinated pregnant women were clustered geographically and by key sociodemographic fac

120 2017, and Dec 31, 2017, 55 enumeration area clusters had 1118 eligible index cases that led to 342 i

121 ual field loss was "detected" if >= N(theta) clusters had deteriorated with p < p(Cluster), chosen em

122 ep CNN trained with 1000 samples or more per cluster has an accuracy of 90% or better for both identi

123 tailed and quantitative understanding of cis-clustering has been hindered by a lack of experimental a

124 is a treatment option for refractory chronic cluster headache (CCH).

125 e to HSPCs that accumulate in intra-arterial clusters (IAC) before colonizing the fetal liver.

126 h single-cell RNA sequencing data to perform cluster identification.

127 Cluster II (28 patients) - the minimally impacted patien

128 The occupancy of the [2Fe-2S] cluster in Fur protein is ~31% in the E. coli iscA/sufA

129 key genes in the FSA biosynthetic gene (FUB) cluster in Fusarium oxysporum f. sp. cubense tropical ra

130 also shows strong homology to a putative ET cluster in human temporal cortex, but with a strikingly

131 regulation of members of the Dlk1-Dio3 miRNA cluster in muscle biopsies of the GRMD dog model.

132 Misexpression of miR-183 cluster in the human retinal epithelial cells leads to t

133 e voxel-wise approach, we identified a small cluster in the left lateral frontal lobe where children

134 Nontruncating pathogenic variants clustered in the C3, C6, and C10 domains (18 of 22, 82%,

135 In our model, mice clustered in two groups displaying high or low clinical

136 a complex landscape with protective epitopes clustering in at least 6-7 antigenic sites.

137 dom effect regression analyses adjusting for clustering in health centres.

138 rface mutation led to a loss of induced PIP2 clustering in MACA, indicating the importance of protein

139 ation solutions with those from unsupervised clustering in which no labels are assigned to the data.

140 Multiple differentially expressed gene clusters in pathways involving metabolism and circadian

141 collated contact tracing data from COVID-19 clusters in Singapore and Tianjin, China and estimated t

142 Alkyl-ligated iron-sulfur clusters in the [Fe(4)S(4)](3+) charge state have been p

143 and propose that the availability of 2Fe-2S clusters in the chloroplast and cytosol is linked to Fe

144 We also found that near-preferring clusters in V3A, located within stereoselective cortical

145 three rural subcounties across 60 villages (clusters) in western Kenya.

146 Active clusters were defined as clusters including internal nodes from 2009 to 2014.

147 with wild type, ablation of the miR-144/451 cluster increased plasma vimentin, while vimentin levels

148 at least one P-element insertion in a piRNA cluster, indicating that repressor alleles are produced

149 ectra under previous conditions is formed by clustering inside the electrospray droplet, but <=5.6% a

150 cant age-dependent concentration differences clustering into four temporal stages, and resulting in a

151 (13)C-ENDOR shows the F229A cluster is mostly (60%) in the "A" conformation but with

152 SirE located in the sir gene cluster is required for the maturation of SirA, but not

153 he third, most robust, model poses that this clustering is due to a short-ranged internuclear attract

154 Two suggest that the initial clustering is due to nuclear repulsion from the cell pol

155 Surprisingly, Ndc80 complex clustering is independent of the organization and number

156 ductions to Guangdong, although phylogenetic clustering is uncertain because of low virus genetic var

157 , annotating the biological identity of cell clusters is an important step before downstream analyses

158 efuted an epidemiological link between the 2 clusters; it also suggested a cascade of patient-to-pati

159 zed the epidemiological understanding of the clusters; it also underlined the risk of covert plasmid

160 m in this area is selection of the number of clusters (K).

161 ion, which can introduce bias into the final clustering labels.

162 election despite some issues associated with clustering large decoy sets and decoy sets that do not s

163 clustering, minimisation variables, baseline cluster-level score of the outcome, and sociodemographic

164 active chromatin at the major translocation cluster locus might facilitate the t(11;14)(q13;32), whi

165 nt with ZDHHC14's importance for Kv1 channel clustering, loss of ZDHHC14 decreases outward currents a

166 I, MbtA, MbtM, and PPTase) from the mbt gene cluster (mbtA-mbtN).

167 We present Spectrum, a new spectral clustering method for complex omic data.

168 ance matrix based on SNP data with the UPGMA clustering method found the best fit to dissect the gene

169 Further, we present a post-processing clustering method that improves the average relative F1

170 We developed a gradient-based unsupervised clustering method to extract the patterns learned by the

171 Automated algorithmic clustering methods that are able to cluster features in

172 g different from prevalent single-resolution clustering methods.

173 Materials and Methods Lesions classified as clustered microcysts at breast US were retrospectively i

174 ing literature that lesions characterized as clustered microcysts demonstrate a very low risk of mali

175 a random effect to adjust for within-school clustering, minimisation variables, baseline cluster-lev

176 applying hybrid density functional theory to cluster models of the bimetallic active sites in the hem

177 borane (1,2-(Ph(2)PO)(2)-1,2-C(2)B(10)H(10)) cluster molecule can lead to the controlled chemical or

178 Here, we show that although structurally clustered mutations in SNAP25 give rise to related synap

179 uronal culture networks and neuronal culture cluster networks by estimating the importance of each ne

180 Cluster Of Clusters Analysis (COCA) is one such approach

181 nucleotide (FMN) and the plant-type [2Fe-2S] cluster of CntB and also of the Rieske-type [2Fe-2S] clu

182 Using WBM and matched cluster of differentiation (CD)138-selected tumor gene e

183 unction in cancer pathogenesis, we found the cluster of differentiation 177 (CD177), a known neutroph

184 ormation of a BsAb with two target antigens, cluster of differentiation 3 (CD3) and B-cell maturation

185 G protein-coupled receptor 120 (GPR120) and cluster of differentiation 36 (CD36), in a spatiotempora

186 of organic compounds generally comparing one cluster of experimentally determined data (e.g., (13)C N

187 Here, we functionally characterize a large cluster of microRNAs (miRNAs) expressed from the materna

188 k of difference in BTMs between PIM/PIMP and cluster of PIM with exceeding BTMs, a more refined defin

189 by localized absorption of laser light by a cluster of single walled carbon nanotubes, with no requi

190 predicted proteins of the pneumocandin gene cluster of the Leotiomycete Glarea lozoyensis than to th

191 te basement membrane analog, also causes the clustering of AQP4 and beta-DG.

192 Hierarchical clustering of OMP occurrence data revealed the relevance

193 ponses are nucleated via the AKAP5-dependent clustering of P2Y(11)/ P2Y(11)-like receptors, AC5, PKA

194 Clustering of patients based on plasma TNF and KYN/TRP y

195 the charged ends of an I-BAR domain, we find clustering of phosphatidylinositol 4,5-bisphosphate-like

196 We illustrate this by utilizing DR-A for clustering of scRNA-seq data.

197 domic dataset, identified lipids driving the clustering of the groups.

198 infected with HIV (n = 23) were analyzed for clustering of their viral sequences (genetic distance, <

199 Our simulations demonstrate dynamic clustering of twitcher-type bacteria with polydomains of

200 c muscle fibers displayed increased distinct clusters of acetylcholine receptors and axon terminals e

201 Network analysis identified 4 Louvain clusters of complications with dense intracluster relati

202 A lipid binding groove and clusters of conserved residues highlight potential funct

203 al allows to generate persistent firing when clusters of cooperative channels are present together wi

204 Centrally, the 24-2C grid identified more clusters of defects than the 24-2 grid, but this was not

205 ies correlated epigenetic features and finds clusters of features that are differentially correlated

206 Six major clusters of genes exhibiting distinctive features were i

207 In addition, the large clusters of histone valleys are found to be enriched at

208 ly consist of oligoclonal to near-monoclonal clusters of intact proviral sequences.

209 ulomas that are characterized by unorganized clusters of macrophages scattered between lymphocytes.

210 To identify the epitopes targeted by clusters of Mtb-specific T cells, we carried out a scree

211 ed with univocal mutational signatures, with clusters of point mutations due to kataegis in close pro

212 or most alphaM4 residues, including those in clusters of polar residues at both the N and C termini,

213 hematical modeling, we here demonstrate that clusters of strongly cooperative ion channels can plausi

214 molecular material that forms as stacks and clusters of thin sheets-each sheet up to hundreds of mic

215 In cardiac myocytes, clusters of type-2 ryanodine receptors (RyR2s) release C

216 cific cis-interactions contribute to lateral clustering on lipid bilayers.

217 sely matching the spatial arrangement of ED3 clusters on the dengue (DENV) viral surface.

218 er of connected cells and is suggestive of a clustered organization.

219 Clustering patients according to their PK parameter valu

220 ucture of the species follows a hierarchical clustered pattern.

221 The 16-palladium(II)-oxo cluster [Pd(16) O(24) (OH)(8) ((CH(3) )(2) As)(8) ] (Pd(

222 The 24-palladium(II)-oxo cluster [Pd(24) O(44) (OH)(8) ((CH(3) )(2) As)(16) ] (Pd

223 also noted that cells exhibited a pronounced clustering phenotype when exposed to near-inhibitory amo

224 lipid-sensing peptide(s) in the ER that can cluster PM-derived cholesterol into transient detergent-

225 us to solve 3D single particle structures of clustered protocadherin, an elongated particle with prev

226 aseline community-based survey followed by a cluster randomised controlled trial of people with hyper

227 We did a cluster randomised trial in rural refugee settlements in

228 We implemented a multi-arm, cluster-randomised community effectiveness trial in thre

229 Post-Acute Stroke Services) was a pragmatic cluster-randomized trial where the hospital was the unit

230 information for sample size calculations of cluster-randomized trials and household surveys, and inf

231 unit (SBU) and a typical 12-connected RE(6) cluster (RE=Eu, Y, Yb, Tb, Ce).

232 0.52 [95% CI 0.16-0.88], p=0.009), lower in clusters receiving RAVC than in those that did not (0.48

233 ctors, the incidence of malaria was lower in clusters receiving rfMDA than in those receiving RACD (a

234 state due to a change in its pK(a) caused by cluster reduction, and (iii) Trp9 rotation is conditione

235 Breakpoint Cluster Region-Abelson kinase (BCR-Abl) is a driver onco

236 e given hydrodynamic tail vein injections of clustered regularly interspaced short palindromic repeat

237 Genome editing by CRISPR (clustered regularly interspaced short palindromic repeat

238 Clustered, regularly interspaced short palindromic repea

239 However, clustering requires upfront algorithm and hyperparameter

240 Mutants in other proline-glutamate (PE)/PPE clusters, responsive to magnesium and phosphate, also sh

241 This clustering results in the formation of gel-like or even

242 Further analysis of an inflammatory gene cluster revealed that genes associated with neutrophil/e

243 Longitudinal analyses of individual clusters revealed that responders could maintain changes

244 allic chemistry, bioinorganic chemistry, and cluster science.

245 Disrupting each cluster selectively impairs native Ded1 association with

246 specific T cell responses were driven by TCR clusters shared between patients with a characteristic t

247 No clusters showed associations between beta-amyloid and gl

248 We propose a clustering similarity measure called Lag Penalized Weigh

249 ples were studied to evaluate within-patient clustering stability in patients with severe asthma.

250 and a concurrent mobilization of CusS out of clustered states in the membrane.

251 s) develop from the hemogenic endothelium in cluster structures that protrude into the embryonic aort

252 a collective signal generated by tumor cell clusters supporting metastatic colonization.

253 ic and health surveys and multiple indicator cluster surveys; 2) multivariable analysis of quantitati

254 mPFC and across the social brain appeared to cluster targets into three social categories: the self,

255 Using clustering techniques applied to targeted sequencing dat

256 e demonstrated the importance of integrative clustering techniques for combining information from mul

257 of dozens of robust recurrent genomic break clusters, termed RDCs, in cultured primary mouse neural

258 within the fatty acid desaturase (FADS) gene cluster that is associated with circulating and tissue c

259 miRNAs), 15 of which map to a single genomic cluster that is exclusive to eutherians.

260 of FBXL5 contains a redox-sensitive [2Fe-2S] cluster that, upon oxidation, promotes FBXL5 binding to

261 B), we discovered transcriptionally-distinct clusters that exhibit neuroanatomical parcellation withi

262 ot (0.48 [0.16-0.80], p=0.002), and lower in clusters that received rfMDA plus RAVC than in those rec

263 e efficacy of machine learning algorithms to cluster the patients into discriminative groups to impro

264 First, we applied hierarchical clustering to intrinsically define the functional bounda

265 urther show that AtNEET transfers its 2Fe-2S clusters to DRE2, a key protein of the cytosolic Fe-S bi

266 sponded more selectively than far-preferring clusters, to low-SF features.

267 ordinated ken net based on nonanuclear RE(9)-clusters, to serve as bicapped trigonal prismatic buildi

268 ious studies have shown that sodium channels cluster together in specific cellular subdomains.

269 nt-back migratory polarity radially from the cluster toward the endoderm.

270 Using the OBE nMS method, cluster-transfer reactions between the holo-dimers and a

271 The consideration of clustered transmission and heterogeneous infectiousness

272 re, we show that synthetic [Fe(4)S(4)]-alkyl clusters undergo Fe-C bond homolysis when the alkylated

273 We performed nonsupervised clustering using latent class analysis to identify subgr

274 involves identifying typhoon track vectors, clustering vectors using a self-organizing map, extracti

275 We report that the HoxC gene cluster was co-opted to be transcribed in the distal lim

276 inescent species resolved how the luciferase cluster was derived by duplication and translocation, fr

277 The enhancer cluster was essential for prenatal and postnatal ventric

278 Gibbs clustering was performed to identify motifs of binding p

279 Furthermore, intravasation of cancer cell clusters was observed following the formation of a mosai

280 Using Ripley's K to quantify clustering, we found that FLAPS configurations were subs

281 Active clusters were defined as clusters including internal nod

282 Putative clusters were identified using maximum-likelihood trees

283 5 intervention clusters and 1,097 from 10 UC clusters were recruited between November 2015 and April

284 her parameter distributions from each of the clusters were statistically different.

285 out ultrafast diffractive imaging of sucrose clusters which are benchmark organic samples.

286 in the formation of oligomannose-type glycan clusters, which were absent on SARS and HKU1 CoVs.

287 recovering the true cell order for each gene cluster while requiring substantially less computation t

288 that XLSSC 122 is a remarkably mature galaxy cluster with both evolved stellar populations in the mem

289 tic analyses revealed that while a few genes cluster with those of other sauropsid species in a gamma

290 h, accumulates to 40-fold higher levels when clustered with a helper hairpin.

291 t decomposition (trtA) in bacterial genomes, clustered with biuH, which encodes biuret hydrolase and

292 ted individuals were grouped into 3 distinct clusters with 7 unclustered individuals.

293 Spatial analysis identified 5 clusters with a high prevalence of unvaccinated pregnant

294 to localize to the cell surface, where it co-clusters with beta-dystroglycan (beta-DG).

295 ein interaction networks and identified gene clusters with functional connectivity.

296 c Akt1 deletion maintains the pro-metastatic cluster within primary tumors but ablates pro-metastatic

297 Disease-mutations cluster within the conserved N-Lip and C-Lip regions tha

298 ic framework to stabilize discrete inorganic clusters within a porous crystalline support.

299 This subpopulation formed clusters within terminal bronchioles and exhibited enric

300 the largest heterometallic supertetrahedral clusters, [Zn(6) Ge(16) ](4-) and [Cd(6) Ge(16) ](4-) ,