ライフサイエンスコーパス: co-activator

1 ase originally identified as a transcription co-activator.

2 ependent of the mitochondrial effects of the co-activator.

3 orylation inactivates Cdc20, a mitotic APC/C co-activator.

4 Yes-associated protein (YAP) transcriptional co-activator.

5 capacity to co-condense with transcriptional co-activators.

6 and association of transcription factors or co-activators.

7 arget genes; Tudor-SN is likely one of these co-activators.

8 cal for interactions with both receptors and co-activators.

9 translocation of the YAP/TAZ transcriptional co-activators.

10 ctivity of mERbeta isoforms with EDCs and ER co-activators.

11 d binding sites of transcription factors and co-activators.

12 TBP also increased steroid receptor co-activator 1 (SRC-1) interaction with the PR NTD and c

13 r peroxisome proliferator-activated receptor co-activator 1 alpha (PGC1alpha) and its splice variant

14 DNA sequence variation in PPAR gamma (PPARG) co-activator 1 alpha (PPARGC1A), a gene encoding a co-ac

15 a lipid-sensing transcription factor (PPARG co-activator 1 alpha, PPARGC1A) to age-related macular d

16 xisome proliferator-activated receptor gamma co-activator 1-alpha (PPARGC-1-alpha or PGC-1alpha), als

17 ue to increased expression of the PPAR-gamma co-activator 1-alpha.

18 8 MAPK activation and induction of PPARgamma co-activator-1 (PGC1alpha).

19 (LBD) interactions with the steroid receptor co-activator-1 (SRC-1) peptide, displacing SRC-1 binding

20 s of both receptors driving steroid receptor co-activator-1 (SRC1) interaction.

21 the transcriptional co-activator PPAR-gamma co-activator-1 alpha (PGC1-alpha).

22 xisome proliferator-activated receptor gamma co-activator-1 alpha, positively control human OPN promo

23 element modulatory factor/androgen receptor co-activator 160), the key mediator of STAT3 ubiquitinat

24 xisome proliferator-activated receptor gamma co-activator-1a (PGC-1alpha), phosphoenolpyruvate carbox

25 xisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha), has emerged as a major

26 xisome proliferator-activated receptor gamma co-activator 1alpha (Pgc1alpha), leading to increased ac

27 n indirectly by modulating SP1 and PPARgamma co-activator 1alpha expression and/or activity independe

28 own of proliferator-activated receptor gamma co-activator 1alpha inhibits spinogenesis and synaptogen

29 Proliferator-activated receptor gamma co-activator 1alpha knockdown also reduces the density o

30 urons, proliferator-activated receptor gamma co-activator 1alpha overexpression increases dendritic s

31 PPARgamma co-activator 1alpha, a co-activator of both CAR and PPAR

32 xisome proliferator-activated receptor gamma co-activator-1alpha (PGC-1alpha) and PGC-1beta, both of

33 xisome proliferator-activated receptor gamma co-activator-1alpha (Pgc-1alpha) is critical for cardiac

34 t that proliferator-activated receptor gamma co-activator-1alpha and mitochondrial biogenesis have im

35 Proliferator-activated receptor gamma co-activator-1alpha knockdown inhibits brain-derived neu

36 xisome proliferator-activated receptor-gamma co-activator-1beta) and the nuclear receptor ERRalpha (e

37 utophagy through the cargo receptor, nuclear co-activator 4.

38 cells, we demonstrate that nuclear receptor co-activator 6 (NCOA6) is essential for estradiol (E2)/E

39 the activation of Wnt ligands, receptors and co-activators accompanies the inactivation of Wnt antago

40 Moreover, we find that the p300 co-activator acetylates H3K64, and consistent with a tra

41 ox-1), proliferator-activated receptor gamma co-activator alpha (Pgc1alpha) and uncoupling protein 2

42 or of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers where

43 rovide evidence that G9a functions both as a co-activator and a co-repressor to enhance cellular prol

44 Z) is a WW domain-containing transcriptional co-activator and a core component of an emerging Hippo s

45 r, RORgammat encoded by Rorc, by acting as a co-activator and co-repressor of STAT3, respectively.

46 nserved component of several transcriptional co-activator and histone acetyltransferase (HAT) complex

47 ently, TRIM24 functions as a transcriptional co-activator and recruits STAT3, leading to stabilized S

48 ical interactions with the Eyes absent (Eya) co-activator and the Groucho (Gro) co-repressor, but the

49 DDX5 can also act as a transcriptional co-activator and we demonstrate that DDX5 interacts with

50 despite unaltered protein interactions with co-activators and -repressors.

51 AD3 interacts with reprogramming factors and co-activators and co-occupies OCT4 target loci during re

52 HIF-1alpha transactivating domain to recruit co-activators and diminished target gene expression.

53 FHL1 binds to the p300/CBP co-activators and disrupts binding with HIF-1alpha.

54 than the currently known TGFbeta1 downstream co-activators and epigenetic modifications.

55 se enhancers are occupied by transcriptional co-activators and loop onto the hes1 promoter within the

56 YAP and TAZ are transcription co-activators and represent the main downstream effector

57 he role of Dube3a/UBE3A as a transcriptional co-activator, and reveal new Dube3a interacting genes.

58 ine-rich (SR) proteins, a family of splicing co-activators, and thereby regulate the splicing of G6PD

59 a process called sigma appropriation, the T4 co-activator AsiA structurally remodels the sigma(70) su

60 ge promoters using an activator (MotA) and a co-activator (AsiA), which function through interactions

61 a Tet-on CHO cell reporter system, RORalpha co-activator assays and inhibition of (RORE)-LUC reporte

62 Here we identify co-activator-associated arginine methyltransferase 1 (CA

63 Co-activator-associated arginine methyltransferase 1 (CA

64 pressors are dramatically more abundant than co-activators at the protein level, but not at the RNA l

65 target genes by promoting association of the co-activator beta-catenin with TCF/LEF transcription fac

66 including some utilizing the transcriptional co-activator beta-catenin, has limited the ability of cl

67 ed RORgammat-driven transcription, decreased co-activator binding and promoted interaction with co-re

68 nd retinoid receptors (ACTR) and the nuclear co-activator binding domain (NCBD) of CREB-binding prote

69 n of the interaction kinetics of the nuclear co-activator binding domain of CREB-binding protein and

70 at the expression of PIMT, a transcriptional co-activator binding protein, was up-regulated in the so

71 s the PPARgamma activation function-2 (AF-2) co-activator binding surface and better enhances co-acti

72 ctivator binding surface and better enhances co-activator binding, affording slightly better transcri

73 y a complex network of factors that includes co-activator binding, autophosphorylation, and dephospho

74 (Nucleosome acetyltransferase of histone H4) co-activator, but not activator Rap1p (repressor-activat

75 It usually functions as a transcriptional co-activator by associating with H3K4me3 and RNA polymer

76 the binding of BMAL1 to its transcriptional co-activator CBP.

77 e TAZ2 or KIX domains of the transcriptional co-activator CBP.

78 by Plk1, which triggers association with the co-activator CBP.

79 5 inhibition leads to reduced recruitment of co-activators CBP, p300, and MLL1, as well as enhanced r

80 mRNAs, whereas concentrations of the T-cell co-activators CD80 and CD86 increased in parallel with r

81 E3 ubiquitin ligase that, together with its co-activator Cdc20, targets cyclin B for destruction dur

82 by catalysing the incorporation of the APC/C co-activator, CDC20, into a complex called the mitotic c

83 Furthermore, the metaphase APC co-activator, Cdc20, is specifically recruited to the ba

84 ion rate of 15 known substrates of the APC/C co-activator Cdh1 under normal conditions and conditions

85 gene, and fzr-1, an orthologue to the APC/C co-activator Cdh1, completely eliminates the essential r

86 mainly in neuronal contexts, when using the co-activator Cdh1/Fzr.

87 tors (GTFs), RNA polymerase II (RNA pol II), co-activators, co-repressors, and more.

88 NA binding domain and a conserved N-terminal co-activator/co-repressor (COAR) domain consisting of A1

89 ntially induced in GSCs by a HIF1alpha/STAT3 co-activator complex and stabilizes Notch1 protein at th

90 chitecture of an estrogen receptor (ERalpha) co-activator complex bound to DNA.

91 The conserved Mediator co-activator complex has an essential role in the regula

92 The co-activator complex is deeply conserved and includes th

93 a component of the MEDIATOR transcriptional co-activator complex led us to address its involvement i

94 The conserved co-activator complex Mediator enables regulated transcri

95 The transcription co-activator complex SAGA is recruited to gene promoters

96 iated factor complex (PAFc) is an epigenetic co-activator complex that makes direct contact with MLL

97 port that depletion of the components of the co-activator complex, Mediator, specifically and potentl

98 eptor beta (Esrrb), which binds the Mediator co-activator complex, to impair enhancers of genes withi

99 lase 2 (HDAC2) or HDAC3, enhanced binding of co-activator complexes containing p300 or CREB-binding p

100 es of the Tup1-Cyc8 co-repressor and Swi-Snf co-activator complexes.

101 omain of the enhancer-linked transcriptional co-activator CREB-binding protein (CBP).

102 Cdc45 association with the MCM ring and GINS co-activator, critical for CMG assembly.

103 lcineurin and CREB-regulated transcriptional co-activator (Crtc).

104 ding protein (Creb1) and its transcriptional co-activators (Crtc1-3) as targets of miR-17, miR-144, a

105 ssion via the de-phosphorylation of the CREB co-activator CRTC2 (ref. 1).

106 fferentiation via the activation of the CREB co-activator CRTC2.

107 romotes dephosphorylation of transcriptional co-activators CRTC2/3 resulting in enhanced gluconeogeni

108 positive regulator of YAP1, by promoting the co-activator, DDX5-mediated stabilization of RNA polymer

109 d protein (YAP) are critical transcriptional co-activators downstream of the Hippo pathway involved i

110 tial activator SIRT1, or its binding partner/co-activator EP300 inhibited RGZ induction of PPARgamma-

111 tivation of the enhancers and recruitment of co-activators, exemplified by p300, causing both enhance

112 ion of the transcription factor Six1 and its co-activator Eya1, develops into placodes and ultimately

113 er the methyltransferase and transcriptional co-activator EZH2 controls the differentiation clock of

114 e GRF-INTERACTING FACTOR (GIF) transcription co-activator family of Arabidopsis thaliana (Arabidopsis

115 cludes the cancer-associated transcriptional co-activator FHL2 from the nucleus in stiff microenviron

116 Drosophila CREB-binding protein (dCBP) is a co-activator for Caudal-regulated activation of ftz.

117 s, stabilizing beta-catenin, a transcription co-activator for OPN expression.

118 ivation domain from the p160 transcriptional co-activator for thyroid hormone and retinoid receptors

119 ivation domain from the p160 transcriptional co-activator for thyroid hormone and retinoid receptors.

120 eracts with, and serves as a transcriptional co-activator for, Lef1 and beta-catenin.

121 Perilipin 5 promotes PGC-1alpha co-activator function by disinhibiting SIRT1 deacetylase

122 at the inhibition of the YAP transcriptional co-activator function by PTPN14 is mediated through thei

123 IRF1 overexpression, suggesting an important co-activator function for this ligase complex.

124 ses reveal that CARM1 exerts transcriptional co-activator function on autophagy-related and lysosomal

125 Merm1 binds the GR co-activator GRIP1 but not GR.

126 uitment of the elongation factor P-TEFb, the co-activator GRIP1, the chromatin remodeling factor BRG1

127 ococcus pneumoniae, the core enzyme GtfA and co-activator GtfB form an OGT complex to glycosylate the

128 iogenesis in yeast (i.e. the transcriptional co-activator Hap4p) is positively regulated by the cellu

129 through the stability of the transcriptional co-activator Hap4p.

130 Knockdown of GATA6 or transcriptional co-activator/histone acetyltransferase p300 decreased AQ

131 Induction of the transcriptional co-activator IkappaBzeta via IL-17 signaling mediated in

132 se metabolism, acting as its transcriptional co-activator in endothelial cells.

133 YAP1 is a transcriptional co-activator in the Hippo signaling pathway, and YAP1-in

134 The role of co-activators in establishing this long-range interactio

135 tential involvement of these transcriptional co-activators in skeletal myopathies.

136 The potential role of c-Jun and specific co-activators in the action of TGF-beta was investigated

137 ts in the re-distribution of transcriptional co-activators, including Brd4, and provides the opportun

138 rylation-dependent interaction of Elk-1 with co-activators, including histone acetyltransferases and

139 scription factor TEAD1 and other YAP-related co-activators, including TAZ, and subsequently induced t

140 mechanisms driving differential beta-catenin/co-activator interactions and their role in adult somati

141 C) signaling regulates specific beta-catenin/co-activator interactions to promote adult progenitor ce

142 We show that the SRY-box 10 (SOX10) co-activator interacts and forms transcriptional complex

143 Creb3l3 mRNA, which encode a transcriptional co-activator involved in energy metabolism and a liver-s

144 owth factor (LEDGF/p75) is a transcriptional co-activator involved in targeting human immunodeficienc

145 We demonstrate that ABHD5, a lipolytic co-activator, is ectopically expressed in CRC-associated

146 to regulate the epigenetic activity of an ER co-activator KDM3A, ACK1 modulates HOXA1 expression in t

147 We report that ACK1 phosphorylates the ER co-activator, KDM3A, a H3K9 demethylase, at an evolution

148 amily member) interacts with transcriptional co-activators like CREB-binding protein (CBP) and its pa

149 ranscription factor and one of its principal co-activators, MAL.

150 e actin cytoskeleton and the transcriptional co-activator MKL1 (MAL).

151 r serum-response factor (SRF) along with its co-activator, myocardin-related transcription factor-A (

152 ecreased expression of progesterone receptor co-activators (NCOA1, -2 and -3, and CREBBP) towards ter

153 of miR-146b, downregulation of the PPARgamma co-activator NCOA4, and PPARgamma, leading to upregulati

154 o bind DNA and that a putative transcription co-activator NDP52 relieves the auto-inhibition of MVI t

155 eptor-gamma coactivator 1alpha, PGC1 related co-activator, nuclear respiratory factor 1, transcriptio

156 We have linked the co-activator of a lipid-sensing transcription factor (PP

157 work identifies the MLL complex as a crucial co-activator of AR and a potential therapeutic target in

158 r of MLL fusion-positive leukemia, acts as a co-activator of AR signaling.

159 at the overexpression of the transcriptional co-activator of beta-catenin, transcription factor 7-lik

160 PPARgamma co-activator 1alpha, a co-activator of both CAR and PPARbeta/delta, was up-regu

161 demonstrate that Ajuba functions as a novel co-activator of ERalpha and that Ajuba/DBC1/CBP/p300 ter

162 is a negative regulator of p53 levels and a co-activator of estrogen receptor.

163 ssociated protein (YAP) is a transcriptional co-activator of hippo signaling pathway, which plays an

164 NPAT is a key co-activator of histone gene transcription, whereas FLAS

165 the nuclear translocation of beta-catenin, a co-activator of IFNbeta enhanceosome.

166 we report that MKL1, the key transcriptional co-activator of many actin cytoskeletal genes, regulates

167 pha (PGC-1alpha), a critical transcriptional co-activator of metabolic gene expression, functions to

168 ne methyltransferase 6 (PRMT6) is a specific co-activator of normal and mutant AR and that the intera

169 mouse model, in which an essential cytosolic co-activator of Nox2 is lost, to characterize bone metab

170 aling which activates PPARGC1a and serves as co-activator of PPARgamma.

171 CRABP2 is a transcriptional co-activator of retinoic acid signaling.

172 Myocardin (MYOCD), a cardiac-specific co-activator of serum response factor (SRF), is increase

173 d the binding between TAp63gamma and p300, a co-activator of TAp63gamma, and consequently counteracte

174 Vav3 is a novel co-activator of the AR.

175 Here we show that Ndfip1, a co-activator of the E3 ubiquitin ligase Itch, restricts

176 ted protein (YAP) is a major transcriptional co-activator of the Hippo pathway.

177 YAP is a transcriptional co-activator of the Hippo signaling pathway that is esse

178 ivator 1 alpha (PPARGC1A), a gene encoding a co-activator of the LCPUFA-sensing PPARG-retinoid X rece

179 he RNA helicase p68 (DDX5) is an established co-activator of the p53 tumour suppressor that itself ha

180 m phosphorylating YAP, a key transcriptional co-activator of the TE-specifying gene Cdx2.

181 TAZ was a critical co-activator of the TH17-defining transcription factor R

182 sent study we identified Tudor-SN as a novel co-activator of the transcription factor peroxisome prol

183 n-related transcription factor A (MRTF-A), a co-activator of the transcription factor serum response

184 CL9) oncogene functions as a transcriptional co-activator of the Wnt/beta-catenin pathway, which play

185 ation and degradation of beta-catenin, a key co-activator of Wnt-induced transcription.

186 r work has focused on targeting AR directly, co-activators of AR signaling, which may represent new t

187 Interestingly, the classical co-activators of SMAD3 complexes, p300 and CBP, were not

188 c regulators, TAF5L and TAF6L, components or co-activators of the GNAT-HAT complexes for the mouse ES

189 Ligands and co-activators of the omega-3 LCPUFA sensing PPAR-RXR axi

190 Eya proteins are essential co-activators of the Six family of transcription factors

191 This occurs via the recruitment of co-activator or co-repressor complexes that epigenetical

192 anscription factor that acts in concert with co-activators or co-repressors to control the activity o

193 PPARgamma requires various co-activators or co-repressors, which may dynamically as

194 ongation, potentially through recruitment of co-activators or release of co-repressors with unique ro

195 recover other regulatory influences such as co-activators or repressors.

196 e present at the Stra6 RARE; 2) RA increases co-activator p300 (KAT3B) binding and histone H3 Lys-27

197 oforms, HIF-1beta, and their transcriptional co-activator p300 as well as glucose transporter 1 (Glut

198 Interestingly, only depletion of co-activator P300 resulted in the decrease of Foxo1 mRNA

199 sulted in recruitment of the transcriptional co-activator p300 to a Bcl11b-repressed promoter with su

200 significantly reduced owing to depletion of co-activator p300 upon treatment with triptolide.

201 upting the cooperation of C/EBPbeta with the co-activator p300.

202 dependent recruitment of the transcriptional co-activator p300.

203 a-catenin with either of the homologous Kat3 co-activators, p300 or CREB-binding protein, differentia

204 transcription and protein levels of the Cdk5 co-activator p35 through ERK1/2, resulting in an increas

205 Nuclear receptor co-activator peroxisome proliferator-activated receptor

206 esis was most likely mediated by the nuclear co-activators peroxisome proliferator-activated receptor

207 The co-activator, peroxisome proliferator-activated receptor

208 an OPN showed that ERRalpha and its obligate co-activator, peroxisome proliferator-activated receptor

209 sity, enhanced expression of transcriptional co-activator PGC-1alpha and increased mitochondrial fatt

210 evels of a gluconeogenic enzyme G6Pase and a co-activator PGC-1alpha were all markedly decreased.

211 nsferase-1, and the integral transcriptional co-activator Pgc-1alpha were significantly downregulated

212 xisome proliferator-activated receptor gamma co-activator (PGC)-1alpha promoter.

213 isome proliferators-activated receptor-gamma co-activator (PGC)-1alpha, a critical master of ROS meta

214 Cyclin E and its co-activator, phospho-cyclin-dependent kinase 2 (p-CDK2)

215 n muscle are mediated by the transcriptional co-activator PPAR-gamma co-activator-1 alpha (PGC1-alpha

216 the mitochondrial biogenesis transcriptional co-activator PPARgamma coactivator 1alpha (PGC-1alpha).

217 on of the adipogenic regulator PPARG and its co-activator PPARGC1B, and reduced expression of LPL.

218 ranscriptional mechanism.The transcriptional co-activator Prdm16 regulates browning of white adipose

219 bly checkpoint proteins Mad2, Mad3 and APC/C co-activator protein Cdc20), we reveal the molecular bas

220 F2C-bound sites by the SAP domain-containing co-activator protein myocardin, and we show that paired

221 ra-terminal domain (BET) family of chromatin co-activator proteins.

222 cer may occur through increased levels of AR co-activator proteins.

223 ates Lys63-linked ubiquitination of the AP-1 co-activator RACO-1, leading to RACO-1 protein stabiliza

224 Mediator is a transcriptional co-activator recruited to enhancers by DNA-binding activ

225 Inhibition of co-activator recruitment to RXR and activation of NF-kap

226 sactivation due at least in part to impaired co-activator recruitment.

227 omoter occupancy and p300, a transcriptional co-activator, recruitment resulting in a defect in targe

228 was recently described as a transcriptional co-activator regulated by miR-135b in vestibular hair ce

229 langiectasia locus (NPAT), a transcriptional co-activator required for expression of histone genes in

230 tion of the NTD to facilitate the binding of co-activators required for maximal transcriptional activ

231 Thus, BRG1 is a SOX10 co-activator, required to establish the melanocyte linea

232 roporin Fps1, in part, by displacing channel co-activators (Rgc1/2).

233 ere we use mathematical modelling to infer a co-activator role for LIGHT-REGULATED WD1 (LWD1) in CCA1

234 one fold-containing subunits of TFIID and of co-activator SAGA are important for the assembly of thes

235 s1p is a common component of transcriptional co-activator, SAGA (Spt-Ada-Gcn5-Acetyltransferase), and

236 ow that cells stably depleted of LKB1 or its co-activator STRADalpha have increased phosphorylation o

237 ranscriptional activators via recruitment of co-activators such as EP300, whereas KLF3 and related me

238 sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting

239 ear receptor alpha (ERalpha), which requires co-activators, such as steroid receptor coactivator-1 (S

240 o signalling pathway and its transcriptional co-activator targets Yorkie/YAP/TAZ first came to attent

241 ast cancer by activating the transcriptional co-activator TAZ.

242 lation of beta-catenin and its transcription co-activator Tcf4 led to activation of Wnt/beta-catenin

243 henotypes via transcription induction of AKT co-activator TCL1A by NANOG.

244 The Eya1 gene encodes a transcriptional co-activator that acts with Six1 to control the developm

245 A point mutation in the Gal1 co-activator that disrupts the interaction with the Gal8

246 ssociated protein (YAP) is a transcriptional co-activator that has been associated with bladder cance

247 recruitment of Gcn5 (also known as Kat2a), a co-activator that has been implicated in transcription i

248 d also its homologue TAZ) is a transcription co-activator that mediates the biological functions of t

249 otein (Yap) has emerged as a transcriptional co-activator that modulates tissue homeostasis in respon

250 n-expressor of PR1 (NPR1) is a transcription co-activator that plays a central role in regulating the

251 ssociated protein (YAP) is a transcriptional co-activator that regulates cell proliferation and survi

252 describe its oncogenic role as a HIF-1alpha co-activator that regulates the HIF-1 transcriptional ne

253 inding protein (CBP) are key transcriptional co-activators that are essential for a multitude of cell

254 inhibitor), and vitamin C (a TET dioxygenase co-activator), that together produced complete demethyla

255 By inhibiting YAP and TAZ transcription co-activators, the Hippo pathway regulates cell prolifer

256 e role of the MEDIATOR (MED) transcriptional co-activator, through its MED16 subunit in Arabidopsis r

257 n with p300 and recruitment of this critical co-activator to promoters.

258 eta-catenin from acting as a transcriptional co-activator to TCF, yet without affecting its stability

259 co-repressors and facilitates recruitment of co-activators to activate transcription.

260 ERalpha requires co-activators to mediate transcription via mechanisms th

261 ription in part by controlling the access of co-activators to their transcription factor partners.

262 ors LRH-1's interaction with transcriptional co-activators to up-regulate gene expression.

263 ntified the RNA helicase DHX15 as a novel AR co-activator using a yeast mutagenesis screen and reveal

264 ing protein co-activators, we depleted these co-activators using adenoviral shRNAs.

265 hrough cAMP-response element-binding protein co-activators, we depleted these co-activators using ade

266 ls for MYC and EBNA2 (an EBV transcriptional co-activator) were significantly enriched in the promote

267 e expression indirectly inhibits the YAP/TAZ co-activators, which maintain the clonogenic potential o

268 CBP/p300 are transcription co-activators whose binding is a signature of enhancers,

269 of this pathway are YAP/TAZ, transcriptional co-activators whose dysfunction contributes to epithelia

270 Transcriptional co-activator with a PDZ binding domain (TAZ) is a WW dom

271 YAP/transcriptional co-activator with a PDZ-binding domain (TAZ) silencing r

272 Transcriptional co-activator with PDZ-binding motif (TAZ) and Yes-associ

273 associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are increased

274 associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are its target

275 associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ), are required

276 Hippo pathway effectors TAZ (transcriptional co-activator with PDZ-binding motif) and YAP (Yes-associ

277 As Camtas can function as co-activators with NK2 proteins in other tissues, we exp

278 -terminal domain (A/B), as a transcriptional co-activator, without ELK1 hyper-phosphorylation.

279 reduces the activity of the transcriptional co-activator YAP and the expression of the NOTCH ligand

280 s allows the proto-oncogenic transcriptional co-activator YAP to promote ferroptosis by upregulating

281 Binding of the transcriptional co-activator YAP with the transcription factor TEAD stim

282 of the Hippo kinase pathway transcriptional co-activator YAP.

283 ation of the proto-oncogenic transcriptional co-activator YAP.

284 The transcriptional co-activators YAP and TAZ are key regulators of organ si

285 We discovered that Tead1 and co-activators Yap and Taz are required for Pmp22 express

286 ave also discovered that the transcriptional co-activators YAP and TAZ are required to maintain PROX1

287 e and inhibit the downstream transcriptional co-activators YAP and TAZ, which are implicated in vario

288 ely regulating the oncogenic transcriptional co-activators YAP and TAZ.

289 of MST1/2 and LATS1/2 and the transcription co-activators YAP/TAZ.

290 y, the Hippo pathway and its transcriptional co-activator Yes-associated protein (YAP) have been show

291 sulting in activation of the transcriptional co-activator yes-associated protein (YAP).

292 g overexpressed AIP4 and the transcriptional co-activator Yes-associated protein (YAP).

293 The transcriptional co-activator Yes-associated protein 1 (YAP1), a key nucl

294 ted by the mechanosensor and transcriptional co-activator Yes-associated protein.

295 MST2 negatively regulate the transcriptional co-activators yes-associated protein 1 and WW domain con

296 osphorylation of the oncogenic transcription co-activator Yki/YAP.

297 the interaction between the transcriptional co-activator Yorkie (Yki) and the transcription factor S

298 nuclear localization of the transcriptional co-activator Yorkie and initiation of growth and prolife

299 genes is coordinated by the transcriptional co-activator Yorkie with its major regulatory input prov

300 t suppressed by removing the transcriptional co-activator Yorkie, suggesting that these roles of Fat

301 represses the growth-promoting transcription co-activator Yorkie.