ライフサイエンスコーパス: co-infection

1 d this greatly increased secondary bacterial co-infection.

2 with chronic HBV and hepatitis D virus (HDV) co-infection.

3 idences of chlamydia, and 1002 incidences of co-infection.

4 without cirrhosis, including those with HIV co-infection.

5 th human immunodeficiency virus/tuberculosis co-infection.

6 powerful in regions with a high incidence of co-infection.

7 eatment option for patients with HBV and HDV co-infection.

8 segments are exchanged among strains during co-infection.

9 nterventions directed at reactivation due to co-infection.

10 n interferon-containing regimen, and HCV-HIV co-infection.

11 n 902 estimates of the prevalence of HIV-HCV co-infection.

12 rventions that put them at increased risk of co-infection.

13 and antiretroviral activities for MRSA/HIV-1 co-infection.

14 Little is known about the extent of HIV-HCV co-infection.

15 tant role of Matrine in combating PRRSV/PCV2 co-infection.

16 reased progression of TB disease, due to HIV co-infection.

17 easured in populations with higher levels of co-infection.

18 reatment during human immunodeficiency virus co-infection.

19 asvir (MK-8742) in patients with HCV and HIV co-infection.

20 patients with HCV mono-infection and HIV/HCV co-infection.

21 this question, we utilized a murine model of co-infection.

22 plus ribavirin in patients with HIV and HCV co-infection.

23 this regimen are warranted in patients with co-infection.

24 al mechanisms underlying the pathogenesis of co-infection.

25 larly in settings with increased HIV and MTB co-infection.

26 face of drug-resistant tuberculosis and HIV co-infection.

27 pathogenesis of HIV-1 during M. tuberculosis co-infection.

28 related conditions, minority status, and HIV co-infection.

29 ally targeted the antigens of the underlying co-infection.

30 ally where there is a high prevalence of HIV co-infection.

31 ts within the environment and the effects of co-infection.

32 gesting a rapid turnover of HBsAg in HBV/HDV co-infection.

33 er health risks upon influenza A virus (IAV) co-infection.

34 lation affected by HIV and hepatitis C (HCV) co-infection.

35 omen reporting drug use and with hepatitis C co-infection.

36 eactivation (HBV-R) in patients with HBV-HCV co-infection.

37 directly to the lungs, in the setting of HIV co-infection.

38 . aureus genes are uniquely essential during co-infection.

39 MDSCs in HIV and Mycobacterium tuberculosis (co)infections.

40 biont species or strains can exist in stable co-infections.

41 nt occurrence of P. aeruginosa and S. aureus co-infections.

42 inactivation may be effective at preventing co-infections.

43 n by parasitic nematodes facilitates malaria co-infections.

44 mune responses in ways that affect microbial co-infections.

45 c target to prevent IAV associated bacterial co-infections.

46 s and rapidly outcompeted wild-type virus on co-infections.

47 rparts, as well as illnesses associated with co-infections.

48 persistence and clearance both in single and co-infections.

49 of the high mortality associated with these co-infections.

50 n protection was observed in the presence of co-infections.

51 to mosquitoes in ways that enhance rates of co-infection?

52 rence was not significant for those with HBV co-infection (0.93, 0.80-1.10) or HCV co-infection (1.10

53 co-infection (1.30, 1.17-1.45), but not HBV co-infection (0.93, 0.82-1.05), than among those with HI

54 ose with HIV only, but not in those with HBV co-infection (1.06, 0.89-1.26).

55 th HBV co-infection (0.93, 0.80-1.10) or HCV co-infection (1.10, 0.97-1.26).

56 nfection (OR 1.37, 95% CI 1.16-1.62) and HCV co-infection (1.30, 1.17-1.45), but not HBV co-infection

57 hazard ratio 1.90, 95% CI 1.53-2.37) and HCV co-infection (1.46, 1.25-1.70) than in those with HIV on

58 tuberculosis is altered by gut Helicobacter co-infection, (2) aerosol Mycobacterium tuberculosis inf

59 One patient (7%) had HIV co-infection, 5/14 (36%) had diabetes mellitus, and 5 (3

60 2958 (8.7%) participants had HBV co-infection, 6149 (18.2%) had HCV co-infection, and 111

61 HIV co-infection accelerates the progression of HCV and repr

62 the robust recruitment of neutrophils in the co-infection, added to the activation of IgG and eosinop

63 The age, site, and co-infection adjusted odds ratios (aORs) for moderate-to

64 d deaths included chronic liver disease, HBV co-infection, alcohol-related conditions, minority statu

65 Thus, co-infection allows IVGs to contribute to within-host sp

66 Notably, HDV co-infection also did not lead to statistically signific

67 Further, endophyte-pathogen co-infection also increased total plant biomass.

68 Co-infections alter the host immune response but how the

69 hin-host epidemiology revealed that nematode co-infection altered malaria propagation by suppressing

70 HPV33 and HPV51 tended to be involved in co-infection among both unvaccinated and vaccinated girl

71 e methods to identify non-random patterns of co-infection among parasite species and determined wheth

72 s, saw STIs as a priority, reported high STI co-infection amongst people living with HIV (PLHIV), and

73 ffered from that of non-allergic mice during co-infection and antibiotic-induced perturbation to the

74 However, the effect of HCV co-infection and DAA treatment on mortality after initia

75 develop humanized mouse models for EBV/KSHV co-infection and identify their complementary effect on

76 stablishes functional control of HBV and HDV co-infection and normalisation of serum aminotransferase

77 a deleterious role for Siglec-1 in TB-HIV-1 co-infection and open new avenues to understand TNT biol

78 er disease, alcoholic liver disease, HIV/HCV co-infection and primary biliary cirrhosis.

79 s egg-negativity is too simplistic to use in co-infection and related studies unless accompanied by i

80 ment of infection and disease, including HIV co-infection and rifampicin-resistant tuberculosis.

81 immunity during human immunodeficiency virus co-infection and summarize recent findings from vaccine

82 11 (55%) of these downstream cases had HIV co-infection and ten (50%) had died by the end of the st

83 terial vaccines show promising efficacy, HIV co-infection and the resulting immunodeficiency prompts

84 have different complications (inflammatory, co-infection and thrombotic) that are identifiable by an

85 is a versatile platform for studying HBV/HDV co-infections and holds promise for performing chemical

86 ikely to be determined primarily by costs of co-infections and in some instances by redundancy of sym

87 Here, we established HBV and HBV/HDV co-infections and super-infections in self-assembling co

88 s had HBV co-infection, 6149 (18.2%) had HCV co-infection, and 1114 (3.3%) had triple infection.

89 tion, Asian or Pacific Islander descent, HIV co-infection, and alcohol-related conditions.

90 the occurrence and clinical significance of co-infection, and increasing awareness of Rhipicephalus

91 prevalence of HCV mono-infection and HIV-HCV co-infection, and the estimated incidence, genotypes, an

92 characterise the prevalence of HCV, HIV/HCV co-infection, and the HCV care continuum in people who i

93 ults in immunological changes that influence co-infections, and might influence fecundity by inducing

94 h serves a population in which TB and TB/HIV co-infection are highly prevalent, but it allowed for ra

95 delay HIV disease progression in areas where co-infections are common.

96 We show that wildlife co-infections are frequent, possibly affecting infection

97 and excessive immunopathological responses, co-infections are noted by short-term and long-term depa

98 d in Pennsylvania poultry, we identified two co-infection ARV variant strains from one ARV isolate ob

99 ed death included chronic liver disease, HCV co-infection, Asian or Pacific Islander descent, HIV co-

100 Lowest rates of natural viral co-infection at baseline and post-LAIV influenza replica

101 to HIV exposure, with the regional burden of co-infection being derived by applying co-infection prev

102 tion of social networks, spatial networks or co-infection best structured the FIVPle network.

103 bloom-terminating viruses, while systematic co-infection between dsDNA and ssDNA viruses posits prev

104 Co-infection between Helicobacter pylori (Hp) and groups

105 ar, Mycobacterium tuberculosis, and HIV, and co-infections between hookworm, P. falciparum and E. his

106 These genes were upregulated by HCV/HIV co-infection but in a greater magnitude.

107 o are infected with hepatitis C virus (HCV) (co-infection), but little is known about its effects on

108 s accelerate hepatic fibrosis during HCV/HIV co-infection by amplifying the expression of HCV-depende

109 We tested for (i) effects of co-infection by other haemoparasites (within guild) and

110 Co-infections by multiple pathogen strains are common in

111 HIV with HBV co-infection can result in greater HIV-related immunosup

112 erstanding the occurrence and consequence of co-infections can be useful in designing disease managem

113 de cohort of patients with hepatitis B and D co-infection, cared for at secondary care centers in Swe

114 From the prospective Canadian Co-infection Cohort (n = 1423), HCV RNA-positive partici

115 es to data from the Canadian HIV-Hepatitis C Co-infection Cohort Study (2003-2014) to estimate the as

116 ferase, using data collected in the Canadian Co-infection Cohort Study from 2003 to 2014.

117 Southern Alberta Clinic Cohort, the Canadian Co-infection Cohort, and the Swiss HIV Cohort study from

118 Using data from the Canadian HIV-HCV Co-Infection Cohort, we applied a difference-in-differen

119 The majority of studies on co-infections concentrate on one of the infecting specie

120 rrhotic patients with HCV genotype 1 and HIV co-infection conducted at the Clinical Research Center o

121 e; specifically when it comes to reservoirs, co-infections, connectedness and wider landscape perspec

122 Underlying medical conditions and bacterial co-infections contributed to the fatal outcome of this i

123 Bacteria-mediated viral co-infection correlated with bacterial adherence to cell

124 We hypothesize that co-infections could be the result of multiple exposure e

125 The high burden of HCV and HIV/HCV co-infection coupled with low-access to HCV services emp

126 me in the context of CT mono (CT+) and CT/MG co-infection (CT+/MG+) may identify biomarkers for infec

127 new model optimized for TB, we find that HIV co-infection does not significantly affect the transmiss

128 bout drug effects among individuals with HIV co-infection, drug interactions, and other sources of he

129 e extraordinarily broad host ranges, however co-infection dynamics have been largely overlooked.

130 dynamics through indirect immunological and co-infection effects.

131 4,650 CO infection episodes were included and the prevalence o

132 difficulties distinguishing and interpreting co-infections, evidence for the presence and directional

133 ly associated with population declines, with co-infections exhibiting many types of interactions.

134 Co-infection experiments with an Escherichia coli strain

135 By using co-infection experiments, we determine that the infectio

136 tantly, bacterial strains that induced viral co-infection facilitated genetic recombination between t

137 nt for age, gender, smoking status, HCV, HBV co-infection, group of exposure, nadir CD4, and CD4:CD8

138 irus type 1 (HIV-1) and Ascaris lumbricoides co-infection has led to significantly improved CD4(+) ce

139 Patients with co-infection (hepatitis B virus or HIV infection), evide

140 Our data suggest that responses to co-infection in allergic hosts likely depends on the imm

141 Tuberculosis co-infection in HIV-infected drug users, including disea

142 t KSHV infection in vivo and the role of EBV co-infection in PEL development have been hampered by th

143 Tuberculosis is the most common serious co-infection in people living with HIV worldwide, but li

144 racterise the epidemiology and burden of HCV co-infection in people living with HIV.

145 infections (STIs) with a significant rate of co-infection in some populations.

146 pidemiology of HCV and the prevalence of HIV co-infection in sub-Saharan Africa.

147 We developed a novel small animal model of co-infection in the humanized mouse to investigate how H

148 ts suggest that in the early stages of acute co-infection in the humanized mouse, infection with HIV

149 atrine possesses activity against PRRSV/PCV2 co-infection in vitro and suppression of the TLR3,4/NF-k

150 e that the long-term maintenance of symbiont co-infections in aphids is likely to be determined prima

151 esults provide a nuanced view of the role of co-infections in determining haemoparasite infection pat

152 igation implicated measles and streptococcal co-infections in most deaths, and also characterised a p

153 ng individual variability between single and co-infections in natural populations.

154 we investigate the source of bacterial-viral co-infections in wild and captive chimpanzee communities

155 l hepatitis, as did 220 patients (one with a co-infection) in the intervention groups.

156 tance of influenza and respiratory bacterial co-infections, including the foundational efforts that l

157 Furthermore, PRRSV/PCV2 co- infection induced IkappaBalpha degradation and phosp

158 sm to the nucleus indicating that PRRSV/PCV2 co-infection induced NF-kappaB activation.

159 Our aim was to determine if S. stercoralis co-infection influenced clinical presentation, cerebrosp

160 e, there are approximately 2 278 400 HIV-HCV co-infections (IQR 1 271 300-4 417 000) of which 1 362 7

161 Fungal co-infection is a recognised complication of respiratory

162 l settings and no effective treatment to the co-infection is available.

163 ata that the reactivation of LTBI during HIV co-infection is likely to be driven by the events of HIV

164 reservoir of susceptible hosts, but that HIV co-infection is not a direct driver for the emergence an

165 HIV co-infection is the most critical risk factor for the re

166 inflammatory tumor microenvironment or viral co-infections is unlikely to increase the cellular entry

167 HIV and hepatitis B virus co-infection leads to substantially increased morbidity

168 versity within orphan viral groups, frequent co-infections, low or rare pathogenicity, and chronic vi

169 Treatment of A. lumbricoides co-infection may delay HIV-1 disease progression by redu

170 S. stercoralis co-infection may modulate the intracerebral inflammatory

171 Co-infections may have unpredictable consequences for th

172 In a murine co-infection model of UTI, an isogenic hma mutant was ou

173 single infection models were combined into a co-infection model that was then verified by our empiric

174 Here, we develop a malaria-LF co-infection modelling framework that accounts for two k

175 We show that early in the co-infection, mutant HIV-1 genotypes that escape suppres

176 with HCV mono-infection (n=159) and HIV/HCV co-infection (n=59) were enrolled.

177 We found that haemosporidian parasite co-infections occurred at a high frequency in the boreal

178 Co-infections occurred in 36% of infected birds.

179 Co-infection of C3HeB/FeJ (C3H) mice with both Leishmani

180 is leads to a healed footpad lesion, whereas co-infection of C57BL/6 (B6) mice leads to non-healing l

181 Retrospective studies indicate that co-infection of hepatitis C virus (HCV) and human immuno

182 Certain bacterial strains increased viral co-infection of mammalian cells even at a low virus-to-h

183 We show that co-infection of mice with Plasmodium yoelii 17XNL (Py17X

184 Co-infection of mice with wild type and a feoB mutant st

185 We discovered that co-infection of murine surgical wounds with Pseudomonas

186 The co-infection of porcine reproductive respiratory syndrom

187 as exclusively expressed and produced during co-infection of this pathogen with the host, e.g., HeLa

188 e demonstrated the first naturally occurring co-infection of two ARV variants in commercial young lay

189 r cohort of HIV-infected individuals HCV/HIV co-infection, older age, alcohol abuse and CD4/CD8 ratio

190 his study investigated the impact of HBV/HIV co-infection on age at presentation and survival of HCC.

191 We further tested the effect of HIV co-infection on diagnostic performance.

192 ata are needed about the effect of hepatitis co-infection on HIV disease progression.

193 is B virus (HBV) and hepatitis C virus (HCV) co-infection on HIV outcomes in patients in China.

194 We aimed to determine the effects of co-infection on mortality from HIV and/or acquired immun

195 Here we assess the impact of HIV co-infection on the emergence of resistance and transmis

196 also discuss the potential impact of malaria co-infections on CHIKV pathogenesis and their relevance

197 der infection can impact immune responses to co-infection or vaccination.

198 EBV/KSHV co-infection (OR = 5.71(1.58-7.12)), HIV positivity (OR

199 s of age, CD4 cell count, HIV control, viral co-infections, or chronic inflammation, and the expansio

200 orts were well matched in terms of race, HCV co-infection, panel reactive antibody, and wait time exc

201 and pfhrp3 gene deletions in multiple strain co-infections, particularly prevalent in Sub-Saharan cou

202 r with respect to liver disease staging, HIV co-infection, prescriber type, and drug or alcohol use a

203 llowing categories: liver disease stage, HIV co-infection, prescriber type, and drug or alcohol use.

204 en of co-infection being derived by applying co-infection prevalence estimates to published numbers o

205 1 381 800) are in PWID, equalling an overall co-infection prevalence in HIV-infected individuals of 6

206 evalence was 5777 (37.2%) of 14 447; HIV/HCV co-infection prevalence was 2085 (13.2%) of 14 435.

207 HIV co-infection promotes both reactivation TB from LTBI and

208 ed by an extraordinarily high blood parasite co-infection rate.

209 re unlikely to account for such variation in CO infection rates.

210 HCV co-infection remains an important risk factor for mortal

211 rug or alcohol use, prescriber type, and HIV co-infection restrictions.

212 own outside the human immunodeficiency virus co-infection setting.

213 r phase 3 trials for hepatitis D virus (HDV) co-infection should be undetectable serum HDV RNA 6 mont

214 Demographic data, TBM severity grade, HIV co-infection status, and clinical endpoints by 3 months

215 counts, viral-load measurements, hepatitis C co-infection status, smoking status, date of death, and

216 aminotransferase (AST) measurements and HIV co-infection status, the discriminatory ability signific

217 The C-EDGE CO-INFECTION study assessed the efficacy, safety, and to

218 ians, especially in children presenting with co-infections such as malaria and HIV.

219 +/- 9 years; 35 with hepatitis-C-virus [HCV] co-infection), TE and FT were performed.

220 Parasite taxa that occurred in co-infections tended to be phylogenetically overdisperse

221 site screening, we identified high levels of co-infections that would have been missed using PCR alon

222 osis epidemic has intensified because of HIV co-infection, the lack of an effective vaccine and the e

223 g individuals infected with only HIV or with co-infection, the mortality from HIV infection and/or AI

224 zation density is probably affected by viral co-infections, the local microbiome composition and muco

225 nd experimental studies for the potential of co-infection to alter disease dynamics across a large ho

226 01-negative adults without hepatitis B virus co-infection to receive coformulated bictegravir 50 mg,

227 Theory predicts co-infections to have major consequences for both within

228 fied safety concern in patients with HBV-HCV co-infection treated with DAAs.

229 ined correlates of HCV infection and HIV-HCV co-infection using bivariate and multivariate regression

230 The rate of respiratory virus co-infection was 2.1%.

231 In HIV-infected individuals, HIV-HCV co-infection was 2.4% (IQR 0.8-5.8) within general popul

232 HIV co-infection was a significant risk factor for disease.

233 Chronic hepatitis B virus or hepatitis C co-infection was allowed.

234 In the multivariable analysis, HIV co-infection was associated with a lower adjusted risk o

235 Co-infection was common (444 episodes/1425 PCP cases), f

236 INTERPRETATION: Malaria parasite co-infection was common in patients presenting to ETUs a

237 In HCV-infected patients with cirrhosis, HIV co-infection was no longer associated with higher risks

238 No co-infection was significantly associated with a differe

239 A virus entirely dependent on co-infection was used to assess relevance of IVGs in viv

240 fection and CIN2+ (with or without HPV-16/18 co-infection) was seen across cohorts for HPV-33, HPV-31

241 , 59, 66, and 68), with or without HPV-16/18 co-infection, was 46.8% (95% CI 30.7-59.4) in the ATP-E,

242 works, coupled with consideration of subtype co-infection, was likely to be important for FIVPle tran

243 osphaera plantaginis, either singly or under co-infection, we find the highest disease prevalence in

244 alyses to determine whether HIV/HCV mono- or co-infection were associated with PASP and PH compared t

245 alterations to known synergistic effects of co-infection were noted in the allergic mice including r

246 Individuals with HCV/HIV co-infection were prospectively enrolled from primary an

247 Risk factors for HIV-HCV co-infection were similar to those observed for HCV mono

248 Bacterial co-infections were identified in >25% of the case-patien

249 ular trends in screening, smoking, and viral co-infections were not evaluated.

250 We found that stable co-infections were possible between all of the combinati

251 We found that within guild co-infections were the strongest predictors of haemopara

252 ith influenza can be aggravated by bacterial co-infections, which often results in disease exacerbati

253 ed 63 patients with HCV genotype 1 and HIV-1 co-infection who were HCV treatment-naive or had history

254 In contrast, co-infection with a high dose of T. muris that induces a

255 We show that co-infection with a low dose of T. muris that leads to t

256 lminth infection can alter susceptibility to co-infection with certain pathogenic bacteria and viruse

257 liver-related morbidity and mortality due to co-infection with chronic hepatitis B and C viruses.

258 ection and other environmental factors (e.g. co-infection with CMV) in the acceleration of the aging

259 lts can be used in future models to describe co-infection with defective interfering particles, which

260 okworm and E. histolytica/dispar, as well as co-infection with each pathogen.

261 (CMV) infection and demonstrate that primary co-infection with genetic variants of CMV was coincident

262 te wild birds are at risk from infection and co-infection with H7, H5, and H9 subtypes.

263 HIV-infected patients receiving ART, chronic co-infection with HBV and HCV is associated with an incr

264 HIV-infected patients receiving ART, chronic co-infection with HBV and HCV is associated with an incr

265 fibrosis as assessed by TE (OR, 95% CI) were co-infection with HCV (7.29, 1.95-27.34), chronic AST (6

266 ndomisation by screening HIV-1 RNA value and co-infection with hepatitis B or C.

267 fected individuals is mostly attributable to co-infection with hepatitis B or C.

268 35 years or younger were more likely to have co-infection with HIV (3.76, 1.72-8.22; p = 0.0009) comp

269 Co-infection with HIV and helminths is common in sub-Sah

270 ts with clinical pulmonary TB due to NTM and co-infection with HIV and the likely role of the seasona

271 Co-infection with HIV increases the morbidity and mortal

272 s a result of shared routes of transmission, co-infection with HIV is a substantial problem, and indi

273 These include multidrug-resistant forms and co-infection with HIV, as well as other factors, such as

274 tionnaire showed that previously treated TB, co-infection with HIV, cigarette smoking, and overcrowdi

275 Co-infection with HIV-1 and Kaposi's sarcoma-associated

276 on with Mycobacterium tuberculosis, a common co-infection with HIV.

277 n and is enhanced in the setting of maternal co-infection with HIV.

278 animal work, implying that in vivo cellular co-infection with HSV-1 and HSV-2 yields viable interspe

279 Co-infection with multiple HPV infections and unidentifi

280 in factors (i.e., distribution of HPV types, co-infection with multiple HPV types, and unidentifiable

281 This was consistent in single and co-infection with no significant delay induced by the he

282 study describes the prevalence of SARS-CoV-2 co-infection with noncoronavirus respiratory pathogens i

283 city of clinical signs and symptoms for PCP, co-infection with other pathogens, and case fatality (11

284 aptive advantage to the meningococcus during co-infection with other pathogens, and promote the emerg

285 We found that co-infection with PLV shifts FIV diversity from bone mar

286 Co-infection with SFTS virus was documented in 66% patie

287 Finally, we show that, in vivo, co-infection with T. congolense accelerates differentiat

288 d complications related to monoinfection and co-infection with these two closely related viruses.

289 European region an increasing prevalence) of co-infection with tuberculosis and HIV and HIV and hepat

290 In fact, PSTVd alone or in co-infection with TYLCSV significantly upregulates the e

291 ipants with laboratory-confirmed Zika (three co-infections with dengue virus, one missing complete bl

292 Co-infections with multiple parasite taxa are ubiquitous

293 new species, Plasmodium lomamiensis sp. Rare co-infections with non-Laverania parasites were also obs

294 and their recent expansion across the world, co-infections with other highly prevalent pathogens such

295 Although QS is characterized in T. brucei, co-infections with other trypanosome species (Trypanosom

296 Our data suggest that co-infections with small intestine-restricted helminth p

297 the RBC specialist's preferred resource; (2) co-infections with the RBC generalist and RBC specialist

298 twork of immune responses against single and co-infections with the respiratory bacterium Bordetella

299 ic HCV genotype 1, 4, or 6 infection and HIV co-infection, with or without cirrhosis, were enrolled f

300 hin the small intestine caused by a helminth co-infection would influence oral prion disease pathogen