ライフサイエンスコーパス: co-regulation

1 and meiosis were overlapping, indicative of co-regulation.

2 n is likely to facilitate co-inheritance and co-regulation.

3 gion (UTR) sequences to mediate the observed co-regulation.

4 heir proximity or if function dictated their co-regulation.

5 howing a higher degree of complexity in gene co-regulation.

6 ical evidence for chromosomal periodicity of co-regulation.

7 xes can be accommodated in the networks with co-regulation.

8 s was originally ascribed to the benefits of co-regulation.

9 omologous genes on chromosomes implies their co-regulation.

10 evaluates ligand-receptor pairs for spatial co-regulation.

11 d to better understand the role of autonomic co-regulation.

12 splicing events, further highlighting their co-regulation.

13 NAs across chromosomes, suggesting potential co-regulation.

14 ylation sites line up to maximize MAPK based co-regulation.

15 ith Elongator and results in transcriptional co-regulation.

16 c stress regulation and dyadic physiological co-regulation.

17 g the mitoribosome as a nexus of mitonuclear co-regulation.

18 ion between parenting stress and poor dyadic co-regulation.

19 t glossy genes were clustered, suggestive of co-regulation.

20 urnover and occupancy during transcriptional co-regulation.

21 ands at the junction of immune and metabolic co-regulation.

22 gene expression level changes and gene-gene co-regulations.

23 nes with recurrent, reproducible patterns of co-regulation across different conditions.

24 TGFM accounts for co-regulation across genes and tissues and models uncert

25 e TF will be inactive resulting in a loss of co-regulation across its target genes.

26 spurious edges -- to report only significant co-regulation alterations.

27 It is tempting to combine the knowledge of co-regulation among different genes and conservation amo

28 This leads to incomplete studies of co-regulation among groups of genes that might be linked

29 ed the PANoptosome and enables crosstalk and co-regulation among these processes.

30 The co-regulation analysis is capable of retrieving gene co-

31 Co-regulation analysis of shared eQTL signals produced w

32 females compared with males, indicating that CO regulation and surveillance are sexually dimorphic.

33 genes usually assume the equivalence between co-regulation and co-expression.

34 hat the CGP map can detect and quantify gene co-regulation and co-localization more effectively than

35 inter- chromosomal interactions and of gene co-regulation and co-localization more effectively than

36 nomy in choosing self-regulation strategies, co-regulation and expressing distress without stigma wer

37 tween dependent co-expression resulting from co-regulation and independent co-expression.

38 t a remaining challenge is to identify their co-regulation and inter-dependence.

39 emporal expression pattern, indicating their co-regulation and interdependence at these stages.

40 eby active genes are clustered to facilitate co-regulation and sharing of transcriptional resources,

41 ng multiplexed proteomics to analyze protein co-regulation and show that this allows the identificati

42 on, including an overestimation of homoeolog co-regulation and the incorrect inference of subgenome a

43 gs of murine GRHL2 and its targets displayed co-regulation and were expressed in trophoblast cells in

44 croevolutionary hypotheses on co-expression, co-regulation, and diversification of these potentially

45 f information which support evidence of gene co-regulation, and optimizes biclusters to be supported

46 ta helps reveal the logic of transcriptional co-regulation, and provides a comprehensive view of inte

47 encodes the intuition that co-expression and co-regulation are not necessarily equivalent and hence w

48 Metabolic co-regulation between biosynthetic pathways for secondar

49 set the existence of a significant level of co-regulation between PDZ domain-encoding genes and thes

50 interaction frequency and in transcriptional co-regulation between pluripotent states.

51 These findings provide new insights into co-regulation between TFs.

52 oach to investigate, for the first time, the co-regulation between the human and SARS-CoV-2 transcrip

53 The potential basis for the co-regulation by darkness and ABA is discussed in light

54 In a select set of genes, co-regulation by dexamethasone and genistein was found t

55 -stimulated FOXO1 target genes that required co-regulation by FOXO1 and TH.

56 eover, molecular and genetic analyses of the co-regulation by GAs and BRs of the control of ovule ini

57 The transcriptional co-regulation by Kr-h1 and dFOXO may represent a broad m

58 lation of the CBF regulon involves extensive co-regulation by other first-wave transcription factors;

59 tions of distant paralogous genes, including co-regulation by shared enhancers and co-transcriptional

60 identified multiple instances of cis-acting co-regulation by using phased genotype data and discover

61 d that kinetic constraints for networks with co-regulation can be analyzed using the approach.

62 methods outlined here could better elucidate co-regulation changes for one or more pathways between t

63 Consistent with this co-regulation, cilia extension by MCCs is more severely

64 o-expression data show poor correlation with co-regulation data even in unicellular yeast.

65 HvST1 is critical for normal synapsis and CO regulation during meiosis in barley.

66 ttern of white blood cell and platelet count co-regulation during acute inflammatory recovery provide

67 (TFs) and microRNAs (miRNAs), to study their co-regulation during craniofacial development.

68 PARP-1-dependent loci expression, confirming co-regulation during developmental phases.

69 s reduced model predicts thrombin and fibrin co-regulation during thrombosis under flow.

70 In general, co-regulation enhances the constraints and therefore lar

71 is also the first report of transcriptional co-regulation existing between two subunits of the multi

72 qRT-PCR analysis of GmSNAPs indicates a co-regulation following SCN infection.

73 cts the occurrence of changes in target gene co-regulation for each candidate modulator, using a meas

74 Moreover, these co-regulations give rise to many enriched network motifs

75 While this co-regulation has been studied using stimulation studies

76 t the prevalent mechanism of transcriptional co-regulation in higher eukaryotes operates with extensi

77 o identify gene modules showing evidence for co-regulation in multiple time series of gene expression

78 arbohydrate and lipid metabolism, suggesting co-regulation in nonhuman primates.

79 sphate receptor (IP3R) and estrogen receptor co-regulation in spinal cord yielded Ca(2+)-dependent no

80 Taken together, our data demonstrate FA gene co-regulation in synchrony with the cell cycle and sugge

81 nsights on the role of the proposed miRNA-TF co-regulation in the cancer stemness axis and its cross

82 pectively, and represent discrete windows of co-regulation in the genome.

83 ytoplasm transportation, and transcriptional co-regulation in the nuclei.

84 MAX effector family, revealed their temporal co-regulation in the same co-expression modules.

85 igation of TF and miRNA regulation and their co-regulation in two major TGCT subtypes.

86 , we describe a novel mechanism of metabolic co-regulation in which an intermediate in one pathway is

87 show that deviations of the observed protein co-regulations in specific cell lines from the consensus

88 and in biological studies that incorporating co-regulation information improves upon the independence

89 y in exploiting prior knowledge, such as the co-regulation information of the genes.

90 ditions is complicated by the fact that such co-regulation is condition-specific.

91 tion the biological assumption - conditional co-regulation is needed to mine a large transcriptional

92 This produced a co-regulation map of the human proteome.

93 bioinformatic analyses suggest this type of co-regulation may be widespread across the transcriptome

94 essons that plasmids have for clustering and co-regulation may explain the logic and organization of

95 encing the affective state and that parental co-regulation may involve both connecting and disconnect

96 Our results suggest that coexpression and co-regulation mechanisms may help to explain some of the

97 enia (SCZ) risk loci may be involved in gene co-regulation mechanisms, and analysis of coexpressed ge

98 ngs point to a common mode for translational co-regulation mediated by G4 structures.

99 We discover three major co-regulation modes of enhancers and find defense-relate

100 These data strongly suggest that miRNA co-regulation modulates the transcriptomic response to a

101 A differential gene expression test and a co-regulation module identification method are further d

102 ation analysis is capable of retrieving gene co-regulation modules corresponding to perturbed transcr

103 distributions that can construct robust gene co-regulation network (CoRegNet) across tens of thousand

104 Our results reveal a detailed CD co-regulation network among the 14 core TFs and provide

105 Protein co-regulation network analyses identified 5 modules asso

106 gene expression profiles outside of the gene co-regulation network context, leading to redundant info

107 thod to directly construct a differential TF co-regulation network from paired disease-to-normal ChIP

108 to capture the gained and lost edges in the co-regulation network.

109 structed miRNA and transcription factor (TF) co-regulation networks for both humans and mice.

110 We used brain-specific gene-co-regulation networks to link GWAS loci and prioritize

111 eraction (PPI), genetic interaction and gene co-regulation networks.

112 d in the nucleus and how this might promote (co)-regulation of specific RNA splicing and editing even

113 pression in marmosets and humans, suggesting co-regulation of 2 parallel anxiolytic pathways in prima

114 Our study focused on the co-regulation of 2,4-diacetylphloroglucinol (DAPG) and p

115 construct CoPheeMap, a network that maps the co-regulation of 26,280 phosphosites.

116 S1 in supporting BL cell growth by mediating co-regulation of a variety of Myc-target genes and co-ac

117 , our analyses provide novel insights to the co-regulation of age-related gene expression in multiple

118 with katB or pexR, indicating PexR-mediated co-regulation of AhpC and KatB as critical for normal gr

119 eable activator of Best2, and elucidated the co-regulation of Best2 by glutamate, GABA and glutamine

120 otypically and transcriptomically, including co-regulation of biological processes and genes importan

121 has been selected during evolution to allow co-regulation of both genes.

122 chondrocytic cells to fluid shear results in co-regulation of c-Jun N-terminal kinase2 (JNK2), c-Jun,

123 n within a clonal population of T cells, but co-regulation of CD8 and SHP-1 levels ultimately limits

124 Co-regulation of cell division processes and metabolic p

125 Co-regulation of chemotaxis genes was also found in publ

126 Moreover, we find a genome-wide co-regulation of chromatin structure by Set1 and Jhd2 at

127 pression activity of c-Myc for gene-specific co-regulation of chronic inflammation.

128 The co-regulation of clustered genes seems to largely depend

129 an inferred lipopolysaccharide response, and co-regulation of CXCL's, SPRR's, S100's with SARS-CoV-2

130 A similar co-regulation of cyclin D1 mRNA by Rac and ERK is seen i

131 We propose that the co-regulation of decision and movement vigor occurs thro

132 Bidirectional promoters enable co-regulation of divergent genes and are enriched in bot

133 quinone oxidoreductase); 2) by investigating co-regulation of entire sets of genes regulated by other

134 Mechanism(s) involved in co-regulation of Erk and Akt in the context of GOF SHP2

135 those of wild-type mice indicating possible co-regulation of expression levels.

136 e II (Pol2) could provide new insights about co-regulation of functionally related gene subsets.

137 Both robust co-regulation of gene expression and potential phasing o

138 y as a heterodimer, as a novel mechanism for co-regulation of gene expression by the DevRS/DosT and N

139 across the genome, potentially facilitating co-regulation of gene expression in response to cold str

140 extensive linkage disequilibrium and genetic co-regulation of gene usage.

141 tions in protein expression arising from the co-regulation of genes and apply it to study the growth

142 properties such as sequence conservation and co-regulation of genes and proteins involved in differen

143 rent androgen concentrations showed temporal co-regulation of genes involved in specific biochemical

144 ption factor(s) from wBm and first report of co-regulation of genes of the T4SS and riboflavin biosyn

145 overed specific TFs that mediate conditional co-regulation of genes within 240 modules across 14 dist

146 oth conservation among orthologous genes and co-regulation of genes within a species.

147 However, co-regulation of genetic effects on gene expression acro

148 ed model (TisCoMM) for TWASs, leveraging the co-regulation of genetic variations across different tis

149 f transcription 3 (STAT3) is involved in the co-regulation of GFAP and VEGF.

150 e proposed a possible model for miRNA and TF co-regulation of HCSC signaling pathways.

151 A methylation in heterochromatin, suggesting co-regulation of heterochromatic features by H2A.W and H

152 the treatment, and iii) reveal differential co-regulation of histone post-translational modification

153 In this review, we focus on the co-regulation of hTERT via transcriptional regulation, t

154 Co-regulation of human immunodeficiency virus (HIV) and

155 PPIs during HSV-1 infection, uncovering the co-regulation of IFI16 and DNA-PK functions as a missing

156 ptome analysis revealed global p53/NF-kappaB co-regulation of immune response genes, including severa

157 The implications of the co-regulation of inflammation and social behavior are di

158 In addition, this co-regulation of key factors within the homology-depende

159 eted screen identifies genes involved in the co-regulation of lipid droplets and peroxisomes, and rev

160 cholesterol biosynthesis pathway as well as co-regulation of many Myc-target genes, including a mode

161 A recent study confirms activity-dependent co-regulation of membrane conductances as a mechanism un

162 esent an important step toward revealing the co-regulation of methylation and gene expression, facili

163 pecific allosteric binding relationships for co-regulation of mRNA degradation.

164 stinct mode of epitranscriptomic control via co-regulation of multiple components of the same signali

165 strates application of a single promoter for co-regulation of multiple genes in a crop plant.

166 vealed that invasion and metastasis requires co-regulation of multiple target genes.

167 se findings demonstrate that transcriptional co-regulation of MYB46 and WRKY33 by AN mediates the coo

168 al recordings indicate that this homeostatic co-regulation of neurite and synapse development preserv

169 We propose that antagonistic co-regulation of neurons controlling alternative actions

170 ric form of aldolase C suggesting that their co-regulation of NF-L expression could be linked to the

171 ion of the hypoxia-response element revealed co-regulation of NICI and the neighboring protein-coding

172 This identification of distant co-regulation of oncogenes represents a strategy for dis

173 been broadly applied to mitochondria, so the co-regulation of OXPHOS genes remains largely unexplored

174 stalk between HR repair and NHEJ through the co-regulation of p53-RPA interaction by DNA-PK, ATM and

175 eir transcriptional regulation of miR-96 and co-regulation of PITX2 activity.

176 ing for genetic coupling that results in the co-regulation of promoters.

177 ynamics highlighted differentiation-specific co-regulation of protein complexes with core histone tur

178 ation, providing additional evidence for the co-regulation of PTEN and PTENP1.

179 Here, we establish a co-regulation of purine and pyridine metabolism in respo

180 etween mitochondria and lysosomes, including co-regulation of Rab7 GTP hydrolysis and Drp1 GTP hydrol

181 -function analysis identified Sox7 and Sox18 co-regulation of robo4 but not fli1a transcripts in zebr

182 lar proteins that modulate virulence and the co-regulation of secreted and non-secreted virulence fac

183 and lysosomal proteins suggests the need for co-regulation of several cellular processes in the progr

184 .5% of SuSy enzyme activity, for evidence of co-regulation of several genes of sugar metabolism.

185 ular and functional contractile phenotype by co-regulation of Smad activity at SMC promoters.

186 Transcriptional co-regulation of sNix and Nix, combined with sNix posttr

187 , chromatin-capture PCR confirmed long-range co-regulation of SOCS2 and FLT3 through changes in promo

188 isease mechanisms involving mismanagement in co-regulation of spatial and temporal transport/translat

189 This stoichiometric co-regulation of STAT3 and Cryba1 could potentiate expre

190 and second, the accuracy of transcriptional co-regulation of subunits should reflect the deleterious

191 es that are regulated by alcohol through the co-regulation of TFIIIB components and define a central

192 n of AMCCs under higher arsenic stress, with co-regulation of the ARG-MRG pairs.

193 The formation of protein complexes and the co-regulation of the cellular concentrations of proteins

194 The association and the possible co-regulation of the classical trait and transcription m

195 We have examined the role of p53 in co-regulation of the DDR and tissue regeneration followi

196 l nucleoid genes, and demonstrate an overall co-regulation of the mitochondrial nuclear-encoded genes

197 For example, co-regulation of the peroxisomal membrane protein PEX11b

198 Our data support the view that co-regulation of the public protease and the private nuc

199 nscriptional regulator of PLS3 and validated co-regulation of the two genes by siRNA-mediated knock-d

200 regulatory elements in common, suggesting a co-regulation of the two genes.

201 that likely explains the necessity for tight co-regulation of the ybgF and tol genes in Gram-negative

202 Co-regulation of these core genes can also provide advan

203 es for transcription factors responsible for co-regulation of these genes during the development of t

204 med an operon structure of tfsAB, suggesting co-regulation of these genes in producing the S-layer.

205 control of acetoin production as well as the co-regulation of these genes with those that influence m

206 ted in cooperative binding, thereby enabling co-regulation of these genes.

207 cells highlights alternative splicing redox co-regulation of TPM1 and ACTN4, key genes involved in c

208 oss a wide spectrum of CKD disease confirmed co-regulation of transcript sets, establishing the disea

209 dissect the sequence features governing the co-regulation of transcription initiation and splicing i

210 encies across transcriptional pathways where co-regulation of transcriptional units may make many gen

211 data define a novel molecular mechanism for co-regulation of two distinct clathrin-independent endoc

212 Existence and co-regulation of two ubiquitous promoters may be a mecha

213 plexes in mammalian Hox gene clusters toward co-regulation of vertebral identity.

214 Co-regulation of WBC-PLT dynamics is a fundamental mecha

215 nd discovered novel characteristics of their co-regulation on downstream target genes, including diff

216 confounding effects of tumor purity and gene co-regulation on gene expression-aneuploidy associations

217 hundreds of TFBS without prior knowledge of co-regulation or coexpression.

218 one another on the chromosome to facilitate co-regulation or couple gene expression to growth rate.

219 , we identified 351 significantly altered TF co-regulation pairs.

220 gh microarray results show a transcriptional co-regulation pattern and do not imply that the gene pro

221 ally-driven ecosystem model to reproduce the co-regulation pattern.

222 -expression, showing significantly different co-regulation patterns between normal and tumor states.

223 eral coherent clusters of genes, which share co-regulation patterns that are highly correlated with t

224 icant disease-associated alterations in gene co-regulation patterns, which also correlate with SLE ac

225 This metabolic co-regulation provides a strategy for P. protegens to op

226 correlations to investigate transcriptional co-regulation provides valuable insight into the nature

227 tory motif analyses, which can capture their co-regulation relationship much better than other scores

228 The mechanism of target co-regulation remained unknown.

229 We developed a method, gene co-regulation score (GCSC) regression, to identify gene

230 In this study, we designed a novel co-regulation score between a pair of operons based on a

231 In the present study, we introduce tissue co-regulation score regression (TCSC), which disentangle

232 regresses TWAS chi-square statistics on gene co-regulation scores reflecting correlations in predicte

233 criptome-wide association studies) on tissue co-regulation scores, reflecting correlations of predict

234 Ignoring the context-specific nature of co-regulation significantly reduces the ability of clust

235 etect the global difference in the proteomic co-regulation structure between healthy and unhealthy su

236 (CISI) of transcriptomic data leveraged gene co-regulation structure to recover spatial expression of

237 ning response, including its dynamic change, co-regulation structure, and elasticity.

238 Despite their evident co-regulation, substitutions of individual Chk1 regulato

239 Such correlations may reveal patterns of co-regulation that are indicative of biochemical pathway

240 to the set, beyond what is expected based on co-regulation to all genes.

241 of histone modifications combine with miRNA co-regulation to form a VDR-regulated feed-forward loop

242 we understand that incorporating conditional co-regulation to study large expression data helps us id

243 enriched for heritability if genes with high co-regulation to the set have higher TWAS chi-square sta

244 AS chi-square statistics than genes with low co-regulation to the set, beyond what is expected based

245 uples, indicating a unique effect of spousal co-regulation toward salient stimuli.

246 Promoter assays confirm their co-regulation via a shared bidirectional promoter, while

247 determined by module-level regulation (e.g. co-regulation via the same signaling system), as well as

248 Co-regulation was able to capture relationships between

249 To test for HuR's role in co-regulation, we measured the reporters in HuR KO cells

250 mple purity or batch effect, as well as gene co-regulation which induces correlations between the exp

251 ed loci generally remain unknown due to gene co-regulation, which leads to correlations across genes

252 t expression of RIG-I and revealed its close co-regulation with interferon-stimulated genes (ISGs) du

253 To obtain clues about possible co-regulation within co-expression clusters, we searched

254 highlight the advantages of leveraging gene co-regulation within the TWAS framework to identify enri

255 Such co-regulation would create a positive feedback circuit;