ライフサイエンスコーパス: co-translationally

1 the cytoplasmic membrane of bacteria occurs co-translationally.

2 helical state is trapped by the NTD, perhaps co-translationally.

3 upport for the hypothesis that proteins fold co-translationally.

4 ociation of NS2 is p7-independent and occurs co-translationally.

5 Protein folding can begin co-translationally.

6 mediates indicated that aggregation occurred co-translationally.

7 sequence, utilizes GTP and, moreover, occurs co-translationally.

8 at RNA polymerase assembly in vivo may occur co-translationally.

9 ated with the SEC61 translocon and functions co-translationally.

10 hese proteins insert into the inner membrane co-translationally.

11 from folding post-translationally to folding co-translationally--a result consistent with previous ex

12 ansferase (NAT) complexes (NatA-NatC), which co-translationally acetylate the N-termini of eukaryotic

13 NatA co-translationally acetylates the N termini of a wide va

14 NatE co-translationally acetylates the N-terminus of half the

15 ly nothing is known about the interaction of co-translationally active chaperones with nascent polype

16 mRNA localizes to the mitochondrial surface co-translationally, aided by the association of a mitoch

17 mitochondrial-targeted proteins is imported co-translationally, although the molecular mechanisms go

18 ion of the first transmembrane segment occur co-translationally and confirm the use of the assay to m

19 at codes for a polyprotein that is processed co-translationally and post-translationally into three s

20 We conclude that hCOA3 stabilizes COX1 co-translationally and promotes its assembly with COX pa

21 SRP binds to inner membrane proteins (IMPs) co-translationally and then targets them to protein tran

22 p50(cdc37) interacted with nascent HRI co-translationally and this interaction persisted during

23 In bacteria, SPase I is targeted co-translationally, and the catalytic domain remains unf

24 Cytosolic proteins begin to fold co-translationally as soon as they emerge from the ribos

25 Accordingly, co-translationally assembling subunits are unstable in i

26 securin associates with nascent separase to co-translationally assist proper folding, Cdk1-cyclin B1

27 based on the fact that p53 dimers are formed co-translationally before the whole tetramer assembles;

28 s in the selection of proteins for export by co-translationally binding to the signal sequences of no

29 rminal betaalpha1 superdomain of apoB, which co-translationally binds and remodels the luminal leafle

30 ndoplasmic reticulum has been shown to occur co-translationally by the signal recognition particle (S

31 embrane proteins are recognized and targeted co-translationally by the signal recognition particle.

32 zed by the rough endoplasmic reticulum (RER) co-translationally cross the membrane through the pore o

33 Here, we show that mRNAs are, in fact, co-translationally degraded.

34 conserved signal recognition particle (SRP) co-translationally delivers newly synthesized membrane a

35 riate culture conditions Hyp is incorporated co-translationally directly at proline codons in genes e

36 Most helical membrane proteins fold co-translationally during unidirectional polypeptide elo

37 n determining whether a nascent protein will co-translationally fold and function or misfold and malf

38 spie algorithm, where the mRNA is allowed to co-translationally fold in response to ribosome movement

39 accumulate prepro-alpha-factor, but not the co-translationally imported protein Kar2, indicating tha

40 ranslation and reducing ribosome stalling of co-translationally imported proteins, thereby positively

41 Sec is inserted co-translationally in a small fraction of proteins calle

42 risingly, moonlighters and paralogs assemble co-translationally in only some but not all of the relev

43 Dimerization occurs co-translationally in the endoplasmic reticulum and is r

44 This unique amino acid is co-translationally incorporated at specific UGA codons t

45 Selenocysteine (Sec) is naturally co-translationally incorporated into proteins by recodin

46 lenium is an essential trace element that is co-translationally incorporated into selenoproteins in t

47 The genetic code expansion strategy, which co-translationally incorporates ncAAs into specific site

48 EMC) cooperates with the Sec61 translocon to co-translationally insert a transmembrane helix (TMH) of

49 ith multiple membrane-spanning segments (MS) co-translationally insert into the endoplasmic reticulum

50 Pyrrolysine (Pyl), the 22nd co-translationally inserted amino acid, is incorporated

51 Most recently a new co-translationally inserted amino acid, pyrrolysine, has

52 How multipass proteins are co-translationally inserted and folded at the endoplasmi

53 ly to "search" for each other after they are co-translationally inserted and folded into the cell mem

54 contain the amino acid selenocysteine (Sec), co-translationally inserted at a predefined UGA opal cod

55 tial studies suggest that pyrrolysine may be co-translationally inserted during protein synthesis, pr

56 Selenocysteine (Sec) is co-translationally inserted into selenoproteins in respo

57 rity of multi-spanning membrane proteins are co-translationally inserted into the bilayer by the Sec

58 Most membrane proteins are co-translationally inserted into the lipid bilayer via t

59 ugh the use of an expanded genetic code that co-translationally inserts sulfotyrosine in response to

60 For a subset of these co-translationally localized mRNAs, their localization i

61 Even though both mRNA types are co-translationally localized we found that the steady st

62 ggest a model in which dlg-1 transcripts are co-translationally localized with the nascent protein: f

63 peptides possess a high percentage of post-/co-translationally modified amino acids, particularly ga

64 se that D348 of the CP47 subunit is post- or co-translationally modified to give a novel amino acid s

65 The newly synthesized EAAC1 protein was co-translationally N-glycosylated with high mannose olig

66 d Cx26 could insert into microsome membranes co-translationally, producing a topological structure in

67 Sec63 is co-translationally recruited to the translocation site a

68 the identity of protein pairs that assemble co-translationally remain unknown.

69 Insertion of pCytf occurred only co-translationally, resulting in processing and accumula

70 The polyprotein self-processes co-translationally such that each constituent protein is

71 n bacteria, these 'non-stop proteins' become co-translationally tagged with a peptide encoded by ssrA

72 interact with a eukaryotic homolog of GroEL co-translationally, thereby sequestering the unfolded pr

73 either post-translationally through Ssa1 or co-translationally through Ssb1.

74 cognition particle (SRP)(3,4) and then moved co-translationally through the Sec61 or SecY channel by

75 c assembly whose subunit composition adjusts co-translationally to accommodate the biosynthetic needs

76 ing biosynthesis, proteins can begin folding co-translationally to acquire their biologically-active

77 at ER export signals of Cab45 and NUCB1 bind co-translationally to SURF4 via a lumenal pocket, contra

78 table interaction with a nascent polypeptide co-translationally, we translated the well studied GroEL

79 otein modifications in eukaryotes and occurs co-translationally when the N-terminus of the nascent po

80 We further show that Mad1 homodimers form co-translationally, which may necessitate a certain codo

81 steine (Sec) is inserted into selenoproteins co-translationally with the help of various cis- and tra

82 hough N-terminal myristoylation is catalyzed co-translationally within the cytoplasm of the parasite,