ライフサイエンスコーパス: coactivator

1 SNW1, a splicing factor and transcriptional coactivator.

2 ting the CSR through its function as a redox coactivator.

3 (PGC1A) is a fasting-induced transcriptional coactivator.

4 d as a putative oncogene and transcriptional coactivator.

5 ned thresholds drive condensation of TFs and coactivators.

6 lated acetyltransferases and transcriptional coactivators.

7 to sequester the transactivation domain from coactivators.

8 anscriptional activators and transcriptional coactivators.

9 nding protein (CREB)-regulated transcription coactivator 1 (CRTC1) by associative learning in physiol

10 tein binding protein (CBP), steroid receptor coactivator 1 (SRC1), and protein arginine methyltransfe

11 rides, increased the expression of PPARgamma coactivator 1 alpha (PGC1A) (P < 0.05), and increased ty

12 The PPARgamma coactivator 1 alpha (PGC1alpha) is a prostate tumor supp

13 ion of proliferator-activated receptor gamma coactivator 1 alpha (PGC1alpha), resulting in gluconeoge

14 melanocortin 2 receptor (MC2R), MC3R, PPARG coactivator 1 alpha (PPARGC1A), and tumor necrosis facto

15 activate hPXR; 5) recruits steroid receptor coactivator 1 to hPXR; 6) activates hPXR in HepaRG cell

16 xisome proliferator-activated receptor-gamma coactivator 1), a Parkin downstream target that can prov

17 xisome proliferator-activated receptor-gamma coactivator 1), a Parkin downstream target that can prov

18 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) and its downstream prot

19 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) is a transcriptional co

20 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha), a critical transcripti

21 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha), induced physiologicall

22 peroxisome proliferator-activated receptor-y coactivator 1-alpha (PGC-1alpha), peroxisome proliferato

23 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha).

24 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha).

25 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1A) is a fasting-induced transcr

26 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) expression that maintain

27 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha) plays a pleiotropic role

28 Peroxisome proliferator-activated gamma coactivator 1-alpha (PGC1alpha) regulates energy metabol

29 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha), as well as inhibition o

30 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1alpha), the cofactor and activa

31 xisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A), a coactivator of the tra

32 xisome proliferator-activated receptor gamma coactivator 1-alpha and oxidative phosphorylation comple

33 xisome proliferator-activated receptor gamma coactivator 1-alpha expression and mitochondrial biogene

34 alpha (proliferator-activated receptor gamma coactivator 1-alpha) and FGF21 (fibroblast growth factor

35 xisome proliferator-activated receptor gamma coactivator 1-alpha, and in line with that, CLL-derived

36 isome proliferator-activated receptor gamma, coactivator 1-alpha.

37 Here, we show that Steroid Receptor Coactivator-1 (SRC-1) interacts with a target of leptin

38 xisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1alpha) plays a critical role i

39 xisome proliferator-activated receptor gamma coactivator-1 alpha (Pgc1a) transgenic (mTg) overexpress

40 ctivated receptor alpha (PPARalpha) and PPAR coactivator-1 alpha (PGC1alpha) signaling with reduced h

41 nal interaction between the steroid receptor coactivator-1 and hPXR but not mouse PXR.

42 enuated the agonist-induced steroid receptor coactivator-1 interaction with hPXR, and, together with

43 nding protein (CREB)-regulated transcription coactivator-1, Jacob, nuclear factor kappa-light-chain-e

44 xisome proliferator-activated receptor-gamma coactivator-1-alpha (PGC-1alpha) pathway.

45 xisome proliferator-activated receptor gamma coactivator 1alpha (P < 0.03), and reduced proinflammato

46 of the transcriptional coactivator PPARgamma coactivator 1alpha (PGC-1alpha) reduced hepatic and plas

47 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha), and fewer mitochondria

48 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) controls BAT-mediated the

49 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha), cyclic AMP-responsive el

50 ted receptor alpha (PPARalpha) and PPARgamma coactivator 1alpha to synergistically drive expression o

51 xisome proliferator-activated receptor gamma coactivator 1alpha, the master regulator of mitochondrio

52 xisome proliferator-activated receptor gamma coactivator 1alpha.

53 proliferator-activated receptor (PPAR) gamma-coactivator 1alpha], PPARalpha, and catalase as key fact

54 xisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha), a master regulator of m

55 xisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha).

56 xisome proliferator-activated receptor gamma coactivator-1alpha expression.

57 xisome proliferator-activated receptor gamma coactivator-1alpha) were higher in interscapular brown a

58 xisome proliferator-activated receptor-gamma coactivator-1alpha]), dynamics (DRP-1 [dynamin-related p

59 xisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta) and PGC-1alpha-related coa

60 ivated receptor gamma (PPARgamma), PPARgamma coactivator 1beta (PGC1beta), and lipoprotein lipase (LP

61 mice; while, compensatory increases in PPARG coactivator 1beta could prevent oxidative damage associa

62 e transcriptional regulator steroid receptor coactivator-2 (SRC-2) controls activation of several key

63 or (AR) and its coregulator steroid receptor coactivator-2 (SRC-2) enhances mitochondrial aconitase (

64 Loss of steroid receptor coactivator-2 (SRC-2) results in a reversal to the fetal

65 as C-MYC, beta-catenin, and steroid receptor coactivator 3 (SRC-3).

66 ing androgen receptor (AR), steroid receptor coactivator 3 (SRC3) and BRD4, for degradation, whereas

67 ogen receptor (ER) recruits steroid receptor coactivator-3 (SRC-3) primary coactivator and secondary

68 eticulocytes and identified nuclear receptor coactivator 4 (NCOA4) as a critical regulator of termina

69 NCOA4 (nuclear receptor coactivator 4) is a widely expressed intracellular prote

70 eterozygous deletion of the nuclear receptor coactivator-5 (Ncoa5) gene resulted in decreased motilit

71 CARM1 orchestrates this coactivator activity in part by depositing the H3R17me2a

72 xisome proliferator-activated receptor-gamma coactivator-alpha (PPARGC1A) messenger RNA (mRNA) in ski

73 e mechanistic understanding of gene-specific coactivator and corepressor functions across the AML1-ET

74 or binding and alterations in the balance of coactivator and corepressor recruitment.

75 This study identifies CHD4 as a HIF coactivator and elucidates the fundamental mechanism und

76 directly interacts with the transcriptional coactivator and histone acetyltransferase p300 and activ

77 a key glycolytic enzyme and transcriptional coactivator and is critical for tumor metabolism.

78 eroid receptor coactivator-3 (SRC-3) primary coactivator and secondary coactivators, p300/CBP and CAR

79 YAP1 is a transcriptional coactivator and the principal effector of the Hippo sign

80 fs respectively, of the Yorkie transcription coactivator and the Warts tumor suppressor.

81 n (TEAD) transcription factors together with coactivators and corepressors modulate the expression of

82 quences on the DNA where AR interaction with coactivators and corepressors modulates transcription.

83 es of these interactions rely on mobility of coactivators and cullin-RING domains, which permits dist

84 anaphase-promoting complex/cyclosome (APC/C) coactivators and its inhibitors is crucial for the dynam

85 RDT-that largely function as transcriptional coactivators and play critical roles in various cellular

86 ption factor (TF) binding and recruitment of coactivators and RNA polymerase II (Pol II).

87 y transcription factors (TFs), which recruit coactivators and the transcriptional machinery to genes.

88 mutant p53, stimulation of steroid receptor coactivators, and induction of protein cross-linking hav

89 cognize downstream promoter elements, act as coactivators, and interact with nucleosomes.

90 m effectors, the YAP and TAZ transcriptional coactivators, are drivers of tumor growth in experimenta

91 tor complex and its domain contributions for coactivator assembly and transcriptional regulation.

92 Coactivator-associated arginine methyltransferase 1 (CAR

93 PRMT4 or coactivator-associated arginine methyltransferase 1 (CAR

94 Here, we identify that coactivator-associated arginine methyltransferase 1 (CAR

95 Moreover, vamorolone uniformly weakens coactivator associations but not corepressor association

96 hase-separated condensates with the Mediator coactivator at super-enhancers.

97 We show that the WNT coactivator beta-catenin interacts both with components

98 /beta-catenin signaling, the transcriptional coactivator beta-catenin is regulated by its phosphoryla

99 mutations caused changes in the affinity of coactivator binding and alterations in the balance of co

100 e binding of the molten globule-like nuclear coactivator binding domain and the disordered interactio

101 d hormone and retinoid receptors and nuclear coactivator binding domain display several kinetic phase

102 h is facilitated by structural shifts of the coactivator binding surface.

103 s that may enable subsequent transcriptional coactivator binding.

104 with the AF-2 helix to stabilize the LBD for coactivator binding.

105 artmentalize its DNA-binding cofactor TEAD4, coactivators BRD4 and MED1, and the transcription elonga

106 Phosphorylation potentiates GRIP1 coactivator but, remarkably, not its corepressor propert

107 egions of thermogenic genes to function as a coactivator by methylating H3K79.

108 alpha1, mediator subunit 12, transcriptional coactivator CBP and TATA-box binding protein.

109 phosphorylation and its interaction with the coactivator CBP.

110 ment of Transportion and the transcriptional coactivator CBP.

111 ily transcription factors, together with the coactivator CBP/p300, but not the CRTC family, are the m

112 anaphase-promoting complex/cyclosome and its coactivator CDC20 (APC/C(CDC20)) form the main ubiquitin

113 The Anaphase Promoting Complex (APC) coactivator Cdh1 drives proper cell cycle progression an

114 We generated unique lists of TFs (n = 2662), coactivators (COA; n = 766); corepressors (COR; n = 599)

115 a basis for understanding assembly of the AR:coactivator complex and its domain contributions for coa

116 However, recent studies on the SAGA coactivator complex are generating new paradigms for how

117 The multiprotein Mediator coactivator complex functions in large part by controlli

118 cn5 Acetyltransferase (SAGA) transcriptional coactivator complex.

119 n structures of the yeast SAGA transcription coactivator complex.

120 lated by activator proteins that recruit the coactivator complexes SAGA (Spt-Ada-Gcn5-acetyltransfera

121 of a set of representative dynamic activator*coactivator complexes, comprised of the ETV/PEA3 family

122 one in deciphering the mechanism of multiple coactivator complexes.

123 histone methyltransferase Ehmt2/G9a, as a RA coactivator controlling somite symmetry.

124 724, that blocks the interaction between the coactivator CREB-binding protein (CBP) and beta-catenin,

125 K:BMAL1 transcription factor complex and its coactivators CREB-binding protein (CBP)/p300 and mixed-l

126 CREB protein prevents its interaction with a coactivator, CREB-binding protein, and subsequently redu

127 ne acetylation facilitate recruitment of the coactivators CRTC2 and BRD4, leading to release of RNA p

128 The cAMP-regulated transcriptional coactivators (CRTCs) are a newly discovered family of in

129 tones and coregulators such as corepressors, coactivators, DNA-binding factors and PTM modifying enzy

130 that LUG could function as a transcriptional coactivator during leaf blade development.

131 owledge of this regulation, focusing on: (i) coactivators, E2 ubiquitin (Ub)-conjugating enzymes, and

132 shRNA screen identified the transcriptional coactivators EHMT2, EHMT1, and CBX3 as important contrib

133 ExoU, which may be a mechanism by which this coactivator enhances the phospholipase activity of ExoU.

134 Here we show that OCA-B, a B cell-specific coactivator essential for germinal center (GC) formation

135 tory mechanism, which depends on ATR and its coactivator ETAA1 and is tightly associated with CHK1 au

136 In contrast, additional coactivators failed to support robust HBV replication in

137 The concept that SNF5 is a coactivator for MYC, however, is at odds with its role a

138 the relevance of its modular nature for its coactivator function in gene regulation.

139 essor binds PPM1G to negatively regulate its coactivator function in the NF-kappaB circuit thereby pr

140 ase 3 and beta-catenin, interfering with Wnt coactivator functions of CCAR2, including in cells harbo

141 anaphase-promoting complex/cyclosome (APC/C) coactivator genes CDC20 and CCS52B (CDH1 ortholog) are c

142 ogen resistance, through upregulation of the coactivator GREB1.

143 Phase-separated condensates of TFs and coactivators have been implicated in assembling the tran

144 nine methyltransferase (PRMT) that acts as a coactivator in a number of transcriptional programs.

145 We show that AGO1 acts positively as a coactivator in estradiol-triggered transcription regulat

146 unctions in the nucleus as a transcriptional coactivator in phytochrome signaling to regulate a disti

147 in the activation of YAP1 (a transcriptional coactivator in the Hippo pathway), which in turn promote

148 rs; upregulation of CHD4 and other known HIF coactivators in human breast tumors was mutually exclusi

149 tion status by dismissing essential SE-bound coactivators including BRD4, Mediator and p300, leading

150 ociation with transcriptional repressors and coactivators including TLE3, TRIM24, TRIM28, and TRIM33.

151 if (TAZ), the key downstream transcriptional coactivators inhibited by LATS1/2.

152 dy we explore the impact of steroid receptor coactivator inhibitor, other targeted anti-cancer compou

153 AF-2) helix 12 mechanism for agonist-induced coactivator interaction and NR transcriptional activatio

154 structured (TF-DNA) and weak multivalent (TF-coactivator) interactions allows for condensates to form

155 PDZ-binding motif (Taz), two transcriptional coactivators known to be activated by WNT/beta-catenin s

156 protein FKBP52 is a steroid hormone receptor coactivator likely involved in neurodegenerative disease

157 of the ETV/PEA3 family of activators and the coactivator Med25, reveals a different molecular recogni

158 Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposu

159 SRF and TEAD mechanosignaling pathways than coactivators MRTF-A and YAP/TAZ, respectively, and may p

160 nuclear localization of the transcriptional coactivator NPR1, a master regulator of SA signaling.

161 iptome reprogramming induced by the unstable coactivator NPR1.

162 bp2 and show that it directly interacts with coactivator Nuclear Transcription Factor Y (NFY) to infl

163 din-related transcription factor A, a potent coactivator of ACTA2 Two-dimensional Western blotting co

164 genetic approach, we have found that Cdh1, a coactivator of APC/C, modulates Mps3 stability.

165 xygnase, exhibits a novel property as a dual coactivator of AR and PKM2 and as such, it is a potent i

166 e interaction between HIF-1alpha and p300, a coactivator of aromatase expression, and suppressed p300

167 ABHD5 is an essential coactivator of ATGL, the rate-limiting triglyceride (TG)

168 Here, we show that GCN5 is an essential coactivator of cell-cycle gene expression driven by MYC

169 e reader proteins, plays a pivotal role as a coactivator of enhancer signaling across diverse tissue

170 eus, where the KDM8/PKM2 complex serves as a coactivator of HIF-1alpha to upregulate glycolytic genes

171 ein, SGO2, serves as a novel transcriptional coactivator of HSF1, contributing to PIC assembly and ex

172 Here we show that Ndfip1, a coactivator of Nedd4-family E3 ubiquitin ligases, is req

173 (NACK), also known as SGK223, is a critical coactivator of Notch signaling and binds to the Notch1 t

174 ypical nuclear IkappaB protein and selective coactivator of particular NF-kappaB target genes, has re

175 LC1 is a regulator of YAP, a transcriptional coactivator of proliferation-promoting and tumor-promoti

176 tional coactivator TAZ (Wwtr1), an essential coactivator of RunX2.

177 din-related transcription factor (MRTF)-A, a coactivator of serum-response factor (SRF), known to pro

178 ZMIZ1 is a coactivator of several transcription factors, including

179 s positively regulated by a meiosis-specific coactivator of the anaphase promoting complex (APC/C) E3

180 neage leukemia-4 (MLL4) is a transcriptional coactivator of the BA-sensing nuclear receptor farnesoid

181 ated protein (YAP), the main transcriptional coactivator of the Hippo pathway, integrates multiple in

182 Here, we show that the transcriptional coactivator of the Hippo pathway, Yorkie (YAP/TAZ in ver

183 we herein show that YAP, the transcriptional coactivator of the Hippo signaling pathway, promotes mai

184 ndicate that TRBP is a novel transcriptional coactivator of the Notch signaling pathway, playing an i

185 ptor gamma coactivator 1-alpha (PPARGC1A), a coactivator of the transcription factor PPAR-gamma that

186 vage-activating protein (SCAP), an essential coactivator of the transcription factor SREBP and thus o

187 Pygopus 2 (Pygo2) is a coactivator of Wnt/beta-catenin signaling that can bind

188 te a large number of target genes, acting as coactivators of DNA-binding transcription factors or as

189 the nucleus and function as transcriptional coactivators of plant defense genes.

190 ntaining transcriptional activator [WWTR1]), coactivators of the Scalloped (Sd or TEAD) DNA-binding t

191 nscriptional cofactor that plays the role of coactivator or corepressor, depending on the cell and pr

192 ndependently of the expression of additional coactivators or transcription factors.

193 d the effects of substitutions in the LBD on coactivator, orthosteric, and allosteric ligand binding.

194 lishing the XPC complex as a transcriptional coactivator, our findings underscore two distinct but co

195 The transcriptional coactivator p300 mediates histone acetylation at DUSP4,

196 chanism by which the HAT and transcriptional coactivator p300 mediates tumorigenesis remains unclear.

197 -3 (SRC-3) primary coactivator and secondary coactivators, p300/CBP and CARM1.

198 alpha) heterodimer bound to DNA, ligands and coactivator peptides, which shows that NR quaternary arc

199 Overexpression of coactivator peroxisome proliferator-activated receptor g

200 The transcriptional coactivator peroxisome proliferator-activated receptor g

201 ression of the mitochondrial transcriptional coactivator peroxisome proliferator-activated receptor g

202 toma cell line Huh7, the coexpression of the coactivators peroxisome proliferator-activated receptor

203 th in ZIP12 deficient cells. Transcriptional coactivator PGC-1alpha, mitochondrial superoxide dismuta

204 The coactivator PGC-1alpha1 is activated by exercise trainin

205 xisome proliferator-activated receptor gamma coactivator (PGC)-1alpha as well as attenuated forskolin

206 xisome proliferator-activated receptor gamma coactivator (PGC)-1alpha is a master regulator of mitoch

207 xisome proliferator activated receptor gamma coactivator (PGC)-1alpha, has been proposed as a master

208 Unlike other coactivators, PGC-1alpha contains protein domains involv

209 increases the levels of the transcriptional coactivator PGC1a and the secreted molecule FNDC5, known

210 ther, these data highlight the critical role coactivator plasticity plays in recognition of disordere

211 and the ANGUSTIFOLIA3 (AN3) transcriptional coactivator play important roles in leaf blade outgrowth

212 Moreover, deletion of the transcriptional coactivator PPARgamma coactivator 1alpha (PGC-1alpha) re

213 ny downregulated genes (including the master coactivators Ppargc1a, Ppargc1b, and their downstream ta

214 tor 1beta (PGC-1beta) and PGC-1alpha-related coactivator (PRC).

215 Studies of the estrogen receptor (ER) coactivator protein Mediator subunit 1 (MED1) have revea

216 implicated the Hippo pathway transcriptional coactivator protein YAP1 as an additional driver of rela

217 We also show that the Tead coactivator protein, Yap, is degraded specifically in th

218 TET2 bound the androgen receptor (AR) and AR-coactivator proteins in LNCaP cell extracts, and TET2 KD

219 into its active conformation, thus affecting coactivator recruitment and antagonizing the transcripti

220 26), displayed submicromolar inhibition in a coactivator recruitment assay and effectively reduced IL

221 says, including mammalian one-hybrid assays, coactivator recruitment assays, and a high-throughput, f

222 iptional activity of ERalpha by facilitating coactivator recruitment to the ERalpha transcriptional c

223 These characteristics include coactivator recruitment, histone modifications, and nonc

224 The AR NTD is the primary site for coactivator recruitment.

225 eorientation of helix 12, thereby preventing coactivator recruitment.

226 However, transcription of these 'coactivator-redundant' genes is strongly affected by rap

227 ctions with PGC1alpha, a key transcriptional coactivator regulating gluconeogenesis, enhancing its ac

228 nes coding for subunits of the transcription coactivator SAGA caused strong genome-wide defects in tr

229 This study reveals a structural role for a coactivator sequential recruitment and biochemical proce

230 hly conserved member of the steroid receptor coactivator (SRC) family, is recruited by transcription

231 ious research revealed that steroid receptor coactivators (Src)-1 and -2 serve a critical cooperative

232 length AR and its complex structure with key coactivators, SRC-3 and p300.

233 is homologous to the human steroid-receptor coactivators SRC1-3 and activates transcription in compl

234 mall molecule stimulator of steroid receptor coactivators (SRCs) attenuates pathological remodeling p

235 PC1 (PC1-CTT) stimulates the transcriptional coactivator TAZ (Wwtr1), an essential coactivator of Run

236 ed by Pkd1 and Pkd2) and the transcriptional coactivator TAZ form a mechanosensing complex in osteobl

237 and nuclear translocation of transcriptional coactivator TAZ, inhibition of which mitigates HO.

238 Hippo pathway transcriptional coactivators TAZ and YAP and the TGF-beta1 (TGFbeta) eff

239 y of Rap1 binding to a known transcriptional coactivator TFIID-binding target, Taf5.

240 matin-modifying complex is a transcriptional coactivator that contains four different modules of subu

241 or 1-alpha (PGC-1alpha) is a transcriptional coactivator that controls expression of metabolic/energe

242 ctivation of Yorkie (Yki), a transcriptional coactivator that drives expression of growth-promoting g

243 -associated protein (YAP), a transcriptional coactivator that regulates cell growth and organ size.

244 ositions human Mediator as a globally acting coactivator that selectively safeguards the functionalit

245 ounding member of a class of transcriptional coactivators that bind the serum-response factor to acti

246 onents of MAPK signaling, the key downstream coactivators that coordinate the transcriptional respons

247 preciated that p300 acts as a critical Notch coactivator, the mechanistic details of p300 in Notch-me

248 but also acts as a steroid hormone receptor coactivator through mechanisms that are unclear.

249 nonglycolysis functions as a transcriptional coactivator to enhance the transcription of several proi

250 tilizes the PPM1G/PP2Cgamma phosphatase as a coactivator to normally induce inflammatory and cell sur

251 ot1L in turn functions as a T3 receptor (TR) coactivator to promote vertebrate development.

252 AP-2beta transcription factor and acts as a coactivator to stimulate Bcl-2 gene transcription.

253 rs activate gene transcription by recruiting coactivators to initiate transcription of their target g

254 nduced following recruitment of CREB and its coactivators to promoter proximal binding sites.

255 eta-catenin, the Wnt pathway transcriptional coactivator, to the adherens junctions in order to maint

256 tance through the activation of AURKA by its coactivator TPX2 emerges in response to chronic EGFR inh

257 Spindlin1 (SPIN1) is a transcriptional coactivator with critical functions in embryonic develop

258 uced nuclear localization of transcriptional coactivator with PDZ binding motif (TAZ) and Yes-associa

259 -associated protein 1 (YAP1)/transcriptional coactivator with PDZ binding motif (TAZ)-dependent, irre

260 ctors Yes-associated protein/Transcriptional coactivator with PDZ domain (YAP/TAZ) and myocardin-rela

261 Yes-associated protein (YAP)/Transcriptional coactivator with PDZ-binding motif (TAZ) activation.

262 rotein (YAP) and its homolog transcriptional coactivator with PDZ-binding motif (TAZ) are key effecto

263 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are the key med

264 We show that FGF18 induces transcriptional coactivator with PDZ-binding motif (TAZ) expression, whi

265 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) in hepatocytes

266 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ), the key downst

267 associated protein (Yap) and transcriptional coactivator with PDZ-binding motif (Taz), two transcript

268 f) chemokine 10 (Cxcl10) and transcriptional coactivator with PDZ-binding motif (Taz), two well-known

269 senescence and inhibition of transcriptional coactivator with PDZ-binding motif (TAZ).

270 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ).

271 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ).

272 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ, also called WWT

273 ac1b, yes-associated protein/transcriptional coactivator with PDZ-binding motif activation/expression

274 tors, yes-associated protein/transcriptional coactivator with PDZ-binding motif via rho kinase, which

275 associated protein) and TAZ (transcriptional coactivator with PDZ-binding motif) are regulators of si

276 associated protein) and Taz (transcriptional coactivator with PDZ-binding motif), as key steps in onc

277 In a hyperactivated transcriptional coactivator with PDZ-binding motif-driven GBM mouse mode

278 r and Yes-associated protein/transcriptional coactivator with PDZ-binding motif.

279 amily proteins are conserved transcriptional coactivators with intrinsic protein phosphatase activity

280 requires phosphorylated, wild-type p53 as a coactivator, with HIF-1alpha binding recruiting p53 to Z

281 and/or electrostatic interactions to bind to coactivators, with few if any specific contacts.

282 Although the Hippo transcriptional coactivator YAP is considered oncogenic in many tissues,

283 The transcriptional coactivators YAP and TAZ mediate this feedback response,

284 hosphorylate and inhibit the transcriptional coactivators Yap and Taz, in nephron progenitor cells.

285 ell as downstream effectors, transcriptional coactivators YAP and TAZ.

286 n factors bound by Hippo signaling-regulated coactivators YAP and TAZ.

287 The Hippo pathway transcriptional coactivators YAP/TAZ were implicated as drivers in GBM p

288 The transcriptional coactivator YAP1 (yes-associated protein 1) regulates ce

289 howed cytosolic retention of transcriptional coactivator Yes-associated protein (YAP) and its paralog

290 Transcriptional coactivator yes-associated protein (YAP) is selectively

291 tin and the neurosuppressive transcriptional coactivator Yes-associated protein (YAP), is critical fo

292 e central pocket, block the interaction with coactivator yes-associated protein with nanomolar appare

293 ther, CS-GRP78 activated the transcriptional coactivators Yes-associated protein (YAP) and tafazzin (

294 nuclear localization of the transcriptional coactivators Yes-associated protein (YAP) and transcript

295 hich serve to inactivate the transcriptional coactivators Yes-associated protein (YAP) and transcript

296 he role of the Hippo pathway transcriptional coactivators Yes-associated protein (YAP) and transcript

297 ere is an early induction of transcriptional coactivator, Yes-associated protein (YAP), which is late

298 promote the activity of the transcriptional coactivator Yorkie (Yki), the sole fly homolog of mammal

299 tricting the activity of the transcriptional coactivator Yorkie (Yki), which normally complexes with

300 ration through interactions with EcR and the coactivator Yorkie (Yki).