ライフサイエンスコーパス: coadministration

1 ng of vancomycin and piperacillin-tazobactam coadministration.

2 und of ivermectin and azithromycin mass drug coadministration.

3 nduction in hepatic tissue was observed upon coadministration.

4 ulations disappear on agonist and antagonist coadministration.

5 effect on QT of chloroquine plus tafenoquine coadministration.

6 xL, effects that were abolished by obatoclax coadministration.

7 o increase plasma D-Serine levels after oral coadministration.

8 ncrease in TUNEL positive staining with iRGD coadministration.

9 nfounding factors, including male sex, NSAID coadministration, advanced age, and prior diagnoses cont

10 linical proof of concept for the use of iRGD coadministration as a strategy to widen the therapeutic

11 In contrast, CBD coadministration blocked THC-induced ERK phosphorylation

12 antibody responses to HZ/su and IIV4 in the coadministration compared with the control group.

13 prior failure of DAA-containing therapy; RBV coadministration did not improve efficacy.

14 is demonstrated that 5-HT2CR/5-HT1BR agonist coadministration did not significantly potentiate the fi

15 ggered EGFR inhibition, but not simultaneous coadministration, dramatically sensitizes a subset of tr

16 dministration with levodopa, and (3) chronic coadministration for 1 month.

17 e 5-10 times higher than those observed with coadministration formulations and nonadjuvanted NiNLPs.

18 On coadministration, geometric mean values of midazolam max

19 istent with our in vitro results, teniposide coadministration greatly enhanced fragmented rAAV8 trans

20 total of 413 subjects were vaccinated in the coadministration group and 415 in the control group.

21 were the HZ/su vaccine response rate in the coadministration group and the noninferiority of the ant

22 The HZ/su vaccine response rate in the coadministration group was 95.8% (95% confidence interva

23 followed by a second HZ/su dose at month 2 (coadministration group), or IIV4 at month 0 and HZ/su at

24 or both the (177)Lu-octreotate group and the coadministration group, followed by tumor regrowth.

25 Neither cyclosporine nor tacrolimus coadministration had a meaningful effect on boceprevir p

26 Coadministration had minimal impact on DRV maximum obser

27 Further, P-NT and liraglutide coadministration improved glycemia and reduced steatohep

28 amic relationships of verapamil and rifampin coadministration in mice.

29 of cetuximab and trastuzumab after SC and ID coadministration in the presence and absence of rHuPH20

30 itumor responses were elicited after U-Omp19 coadministration, increasing survival of mice in a murin

31 ing of the treated tumors revealed that iRGD coadministration induced a vesicular transport pathway t

32 injection with either (177)Lu-octreotate or coadministration of (177)Lu-octreotate and rA1M.

33 Coadministration of 25(OH)D in the context of OVA-specif

34 Coadministration of 3 mg/kg ADX_5322_A02 anti-PD-L1 adne

35 munoprotection could be improved by the oral coadministration of 3 Salmonella carrying the plasmids t

36 ake of either tracer was not affected by the coadministration of 40 nmol ( approximately 5 mg/kg) of

37 Tumor uptake was decreased by the coadministration of 400 mug of unlabeled conatumumab (me

38 nes to treat HR-defective tumors and for the coadministration of 6-TG and allopurinol as an immunomod

39 c potency could be significantly enhanced by coadministration of a 5-HT1BR agonist and whether this w

40 Therefore, coadministration of a 5-HT1BR agonist potentiates the an

41 Coadministration of a bacterial adjuvant with oral immun

42 physema, and this resistance was reversed by coadministration of a beta-catenin inhibitor, suggesting

43 circadian clock by melatonin was blocked by coadministration of a GIRK channel antagonist tertiapin-

44 d to deliver better synergistic effects than coadministration of a mixture of multiple drugs.

45 In a rat cardiac transplantation model coadministration of a nonefficacious dose of prodrug 14

46 We found, however, that coadministration of a novel emulsome adjuvant, which enh

47 Coadministration of a P2Y6 receptor antagonist blocked t

48 In diet-induced obese mice, the coadministration of a peripheral CB1R inhibitor with lon

49 Notably, in a murine model of lung cancer, coadministration of a PI3Kdelta-specific inhibitor with

50 lacebo-controlled trial evaluating the novel coadministration of a probiotic and peanut OIT and asses

51 The studies described herein suggest that coadministration of a PXT-derived agent with cancer chem

52 Coadministration of a PYK2 inhibitor and Na2S did not re

53 Consistent with this result, coadministration of a selective pharmacological inhibito

54 inimum 14-day washout period, and subsequent coadministration of a single 0.5-mg dose of tacrolimus w

55 minimum 8-day washout period, and subsequent coadministration of a single 10-mg oral dose of cyclospo

56 ble solution, we rescued the IgG response by coadministration of a Toll-like receptor 9 agonist, amon

57 ed replication plan of key experiments from 'Coadministration of a tumor-penetrating peptide enhances

58 plicate selected experiments from the paper "Coadministration of a tumor-penetrating peptide enhances

59 Coadministration of adjuvants enhanced anti-P1 serum ant

60 In addition, we found that coadministration of AdVCA0848 with another adenovirus se

61 Most vaccines depend on coadministration of Ags and adjuvants that activate APCs

62 Coadministration of amifostine decreased renal uptake of

63 a after administration of vancomycin without coadministration of aminoglycosides.

64 in particular when considering the frequent coadministration of aminoglycosides.

65 lower than in wild-type mice, and intranasal coadministration of an anti-C3a mAb with P to P(-/-) mic

66 Coadministration of an anti-IL-6 antibody with polyI:C r

67 this drug can be heightened significantly by coadministration of an artificial nucleoside (5-nitroind

68 of rotavirus, a result strictly dependent on coadministration of an effective adjuvant.

69 in-8 (IL-8) from tumors into the plasma, and coadministration of an IL-8 neutralizing antibody resens

70 The coadministration of an ISCOMATRIX vaccine with the TLR3

71 iated, in part, through modulation of OT, as coadministration of an OT receptor antagonist prevented

72 ased food intake, which was blocked by prior coadministration of analogue 3.

73 Coadministration of anti-41BB mAb with TriVax enhanced R

74 Coadministration of anti-PD-L1 or anti-CTLA-4 singly wit

75 cytokines in recipient mice, especially with coadministration of anti-PD-L1.

76 Coadministration of antigen with rapamycin simultaneousl

77 trong antibody responses in mice without the coadministration of any additional adjuvant by noncovale

78 redictive of clinical response revealed that coadministration of Apo2L/TRAIL with AMG 655 leads to in

79 Inhibition of Nox2 by coadministration of apocynin or diphenyleneiodonium was

80 Moreover, lowering the initial viral load by coadministration of ART and immunotherapy enabled prolon

81 Coadministration of artemether and nimodipine, a calcium

82 of ivermectin for scabies and impetigo, with coadministration of azithromycin for trachoma.

83 Furthermore, systemic coadministration of beta-glucan plus pancreatic beta cel

84 These effects were reversed by coadministration of bicuculline.

85 inding in the PD-L1(+) spleen was reduced by coadministration of BMS-986192.

86 Finally, coadministration of BMS354825 and UCN-01 suppressed huma

87 Coadministration of boceprevir with cyclosporine/tacroli

88 Accordingly, coadministration of cabozantinib and MEK inhibitors trig

89 Coadministration of caffeine with a low dose of l-DOPA r

90 rotein, with or without a single intravenous coadministration of CH31 bnAb at birth.

91 that were able to neutralize tier 2 viruses, coadministration of CH31 did not have a large impact on

92 Coadministration of ChABC and plasmin enhanced the tPA(-

93 All the effects were reverted by coadministration of compound C (9), an AMPK inhibitor, o

94 the human tumor HeLa and PC3 cells, but the coadministration of copper increases the ligands effects

95 Importantly, coadministration of CPA with a human CAR activator led t

96 ma was associated with the number of days of coadministration of CYP3A inhibitors (r=0.30; p=0.006).

97 Furthermore, oral coadministration of D-serine with 11h enhanced the plasm

98 Consequently, coadministration of D-Serine with a DAAO inhibitor has b

99 Coadministration of DA with the broad spectrum excitator

100 Coadministration of DD with IL-15, which binds to IL-2Rb

101 f platelet function were reduced less by the coadministration of dexlansoprazole or lansoprazole with

102 a post hoc analysis to assess the effect of coadministration of different OPV formulations on RV1 im

103 Both monotherapies and coadministration of DNase I and rhADAMTS13 revealed a ca

104 om the baseline by up to 90% (P < 0.0001) by coadministration of DO3A-exendin-4 at 100 mug/kg.

105 The coadministration of DOACs with the antiretroviral (ARV)

106 p preventive chemotherapy programmes for the coadministration of drugs to target lymphatic filariasis

107 Here we show that coadministration of effector Ab substantially improved t

108 The coadministration of EFV400 with anti-TB treatment can be

109 ed WAVE1 dephosphorylation was attenuated by coadministration of either a D1 dopamine receptor or NMD

110 Coadministration of either ATROSAB or EHD2-scTNFR2 into

111 r soluble Abeta levels, effects negated with coadministration of elacridar, a P-gp inhibitor.

112 , dual inhibition of IL-1beta and IL-18, and coadministration of endothelial progenitor cells and str

113 However, coadministration of epiallopregnanolone sulfate with cho

114 Coadministration of ES with VEGF inhibitors may offer a

115 or lansoprazole with clopidogrel than by the coadministration of esomeprazole or omeprazole.

116 Coadministration of excess unlabelled DPA-713 abrogated

117 icacy in poorly radioimmunogenic tumors, and coadministration of exogenous adjuvants that promote cDC

118 Coadministration of EZH2 inhibitor GSK126 and RAC1 inhib

119 navir, efavirenz, and tenofovir to guide the coadministration of faldaprevir with these agents in hum

120 Coadministration of flavopiridol and obatoclax synergist

121 In rats, coadministration of FLX (2.5, 5.0, and 10.0 mg/kg) incre

122 ons conferring resistance was high; however, coadministration of fosfomycin with ceftazidime-avibacta

123 Coadministration of FXI ASO with enoxaparin or the antip

124 Coadministration of gadolinium-based contrast and a CCR2

125 ependently of estradiol, and the response to coadministration of genistein and dexamethasone was uniq

126 Coadministration of ghrelin and GH, but not ghrelin alon

127 hamide > 5 g/m(2) (P = .019), but not to the coadministration of GnRHa during chemotherapy (odds rati

128 therapy or tumor burden but was augmented by coadministration of granulocyte-colony stimulating facto

129 However, coadministration of GT with BH(4) did not result in a fu

130 Coadministration of HG-829 fully restored in vivo antitu

131 Notably, coadministration of hhep25 and hemoglobin but not admini

132 Furthermore, we found that coexpression or coadministration of HSP70 from VSV vector significantly

133 Our results suggest that short-term coadministration of HU and Akti XII has immediate benefi

134 microscopy, we demonstrated that short-term coadministration of HU and Akti XII, an AKT2 inhibitor,

135 The coadministration of ICI 182,780 blocked the effects of D

136 Coadministration of ICT2588 with doxorubicin resulted in

137 We hypothesized that coadministration of IL-12 with a murine anti-HER2/neu mA

138 In contrast, coadministration of IL-13 with a higher dose of IL-17 de

139 However, coadministration of IL-15 with DD could alleviate this p

140 Intratracheal coadministration of IL-17A and TNF-alpha in mice induced

141 osis, and this protection was reversed after coadministration of IL-17A.

142 This effect is significantly increased by coadministration of IL-33 (5-100 ng/mL) in both cell typ

143 der investigation and include the following: coadministration of immunosuppressive and prosurvival ag

144 Coadministration of ineffective lorcaserin (0.1 mg/kg pe

145 rlying signaling mechanisms involved through coadministration of inhibitors of phospholipase C (PLC),

146 In this study, the postoperative coadministration of iNO and oral sildenafil in patients

147 administration in group B improved after the coadministration of iNO, and thus PaO(2)/inspired fracti

148 Coadministration of insulin and FFAs, however, abolished

149 erefore, supports the WHO recommendation for coadministration of IPTi with sulfadoxine-pyrimethamine

150 In a KRAS-induced orthotopic PDAC model, coadministration of iRGD enhanced the uptake of an irino

151 Thus, coadministration of iRGD may be a valuable way to enhanc

152 Coadministration of IV vancomycin and piperacillin/tazob

153 s of this study clearly demonstrate that the coadministration of key enzyme inhibitors can effectivel

154 Coadministration of KGF with IAV markedly accelerated th

155 SS1P uptake by kidney is reduced by coadministration of l-lysine.

156 ve prediction of DDI risk indicated that the coadministration of lapatinib or imatinib at clinical do

157 Coadministration of lapatinib with obatoclax caused syne

158 Coadministration of lapatinib with obatoclax elicited au

159 ufficient to ameliorate hyperglycemia alone, coadministration of leptin with islet transplantation ro

160 The coadministration of lithium with paclitaxel also allows

161 nd human cancer models in vivo, we show that coadministration of low-dose Cilengitide and Verapamil i

162 ction of tolerance to rhASB was initiated by coadministration of low-dose corticosteroids, rituximab,

163 This effect was completely antagonized by coadministration of luzindole in all groups.

164 Coadministration of LY2828360 (0.1 mg/kg per day i.p. x

165 Coadministration of Met prevented Cfz-induced FS reducti

166 Coadministration of methadone with antiretrovirals in pa

167 However, coadministration of methylprednisolone acetate results i

168 ral neostriatum compared with TBZ alone, and coadministration of mianserin with TBZ and FLX attenuate

169 counted for these apparent benefits, because coadministration of mifepristone prevented stress-induce

170 Coadministration of monovalent, bivalent, or trivalent O

171 Long-term coadministration of MOR and DOR agonists caused cAMP ove

172 ntestine, as well as niche competition after coadministration of multiple species of the microbiota.

173 oth CYP2J2 and CYP2C8 transgenic mice during coadministration of N-nitro-l-arginine methyl ester and

174 ivity and inhibit neurotransmission, and the coadministration of N-type Ca(2+) channel blocker facili

175 Coadministration of NAC and a nonpeptidic GpIIb/IIIa inh

176 In vivo, coadministration of naive TCR transgenic T cells (2D2 T

177 Coadministration of nanoformulated RIF and INHP provided

178 ation of fear conditioning was attenuated by coadministration of nicotinic antagonist.

179 a production and provide a rationale for the coadministration of NK cell-activating cytokines with th

180 of the tachykinin precursor 1 (Tac1) gene or coadministration of NK1 receptor antagonists produces lo

181 Interestingly, coadministration of NRTN and liraglutide normalized hype

182 Coadministration of NYVAC-KC with the DC-targeting vacci

183 Coadministration of O6-benzylguanine (O6BG) can restore

184 In healthy controls, coadministration of OBV/PTV/r + DSV + darunavir (DRV) lo

185 Therapeutic coadministration of OCA and SUMOylation inhibitors drast

186 of anti-PD-L1 IgG plus HER2.CAR T cells and coadministration of Onc.Ad in an HER2(+) prostate cancer

187 Coadministration of oral insulin improved and prolonged

188 f safety and feasibility of large-scale mass coadministration of oral ivermectin and azithromycin, wh

189 s with delirium were associated with days of coadministration of P-glycoprotein inhibitor (r=0.35; p=

190 Likewise, the coadministration of PA resulted in a marked increase in

191 In a similar manner, the coadministration of PA resulted in an equally impressive

192 Coadministration of paclitaxel increased the uptake of F

193 This study evaluated whether coadministration of parenteral iron improves ESA efficac

194 f cisplatin was significantly potentiated by coadministration of PD173074.

195 prior to voriconazole (OR, 6.21; P = .008), coadministration of penicillins (OR, 6.12; P = .03), and

196 Coadministration of phosphoramidon or thiorphan increase

197 In addition, coadministration of PIKA with a poorly immunogenic H5N1

198 Coadministration of pioglitazone with peginterferon/riba

199 Although it is clear that coadministration of poly(I:C) with antigen elicits stron

200 Coadministration of PQ reduced substantially the rate of

201 Coadministration of pralatrexate and romidepsin was safe

202 Preadministration and coadministration of probiotics ameliorated C. rodentium-

203 courage the further clinical development and coadministration of protein and viral vector vaccine pla

204 wed by two additional ALVAC vaccinations and coadministration of purified bivalent gp120 proteins (AI

205 Energy intake during coadministration of PYY(3-36) and oxyntomodulin was redu

206 loped for cancer therapy may pose risks with coadministration of radiotherapy.

207 Similarly, coadministration of rapamycin with AAV vectors resulted

208 Moreover, coadministration of rapamycin with L-DOPA counteracts L-

209 ding to these simulations, it is likely that coadministration of rifampicin with these LA formulation

210 olimus are affected to a large extend by the coadministration of ritonavir in HIV-infected transplant

211 Coadministration of rizatriptan, a 5-HT(1B/D) agonist an

212 Coadministration of SAHA and olaparib synergistically in

213 Indeed: (1) coadministration of SB216763 and atractyloside (MPTP ope

214 rexcitability by minocycline was overcome by coadministration of sIL-6R, showing that sIL-6R is requi

215 of this study was to examine the effects of coadministration of sildenafil and inhaled nitric oxide

216 ated the induction of protective efficacy by coadministration of single-antigen vectors or vaccinatio

217 We hypothesized that the in vivo coadministration of specific enzyme inhibitors would imp

218 tream mediators of IFN-gamma signaling, upon coadministration of spermidine to IFN-gamma-treated cell

219 Coadministration of subtoxic or minimally toxic concentr

220 , and that these effects can be amplified by coadministration of sunitinib.Significance: These findin

221 ls can be resensitized to immunotherapy with coadministration of targeted inhibitors to antiapoptotic

222 uated the increase in oral tremor induced by coadministration of TBZ (0.75 mg/kg) with FLX (5.0 mg/kg

223 Consistent with these behavioral data, coadministration of TBZ and FLX decreased DA tissue leve

224 appropriate dose adjustments needed for safe coadministration of telaprevir with cyclosporine or tacr

225 Coadministration of tempol, a superoxide dismutase mimet

226 In both groups, the coadministration of the 2 drugs resulted in a significan

227 Coadministration of the 3D regimen with the evaluated HI

228 neurons in the DRN because it was blocked by coadministration of the 5-HT(1A) agonist 8-OH-DPAT [((+/

229 decreased synaptic GluA1 expression, whereas coadministration of the A1AR agonist inhibited both coca

230 e signal in the brain of mice increased with coadministration of the ABCG2 inhibitors Ko143, gefitini

231 Importantly, coadministration of the adjuvant with the Pneumovax vacc

232 Moreover, coadministration of the CDK4/6 inhibitor palbociclib in

233 ta in PIC-induced effects was studied by the coadministration of the cytokine antibodies with PIC, an

234 ist SKF81297 induced pMeCP2 widely; however, coadministration of the D(2)-class agonist quinpirole re

235 herapies in Tk2(-/-) mice: (1) dT+dC and (2) coadministration of the deaminase inhibitor, tetrahydrou

236 Coadministration of the extracellular protein OVA and th

237 The amnestic effect of AM251 was rescued by coadministration of the GABAA receptor antagonist bicucu

238 Severe bradycardia/bradyarrhythmia following coadministration of the HCV-NS5B prodrug sofosbuvir with

239 Strikingly, coadministration of the HDAC inhibitor sodium butyrate w

240 As a pharmacological parallel, coadministration of the high-affinity D2 agonist, aripip

241 These effects were counteracted by coadministration of the mitochondrial complex I inhibito

242 Importantly, coadministration of the mTOR inhibitor rapamycin reduced

243 dation process was efficiently suppressed by coadministration of the N-WASP inhibitor wiskostatin.

244 icity and antitumor potency were enhanced by coadministration of the natural killer T-cell ligand 7DW

245 ty in vitro but not by the same magnitude as coadministration of the peptide and these antibiotics.

246 Y-maze model, an effect fully reversible by coadministration of the selective 5-HT(2C) antagonist SB

247 Coadministration of the serotonin 5-HT2A/2C antagonist m

248 eralgesic action compared with the equimolar coadministration of the single agents.

249 Intraplantar coadministration of the TRPA1 receptor antagonist AP-18

250 Interestingly, coadministration of the two agents acutely increased the

251 1D11 was equivalent or superior to losartan; coadministration of the two agents was not superior to 1

252 Coadministration of these agents (CAd-VECPDL1) exhibited

253 he period of protection against disease, but coadministration of this dose should not interfere with

254 alone also decreased islet inflammation, and coadministration of this reagent and a suboptimal dose o

255 In vivo, coadministration of tPA improved the anticancer efficacy

256 vide a better understanding of the effect of coadministration of transporter modulators on anticancer

257 xenograft model insensitive to trastuzumab, coadministration of trastuzumab with a fixed dose of T-D

258 The coadministration of TVR and unboosted ATV results in inc

259 Coadministration of UPI peptide with cytotoxic chemother

260 d PBMCs from the same patient, we found that coadministration of urelumab and nivolumab was sufficien

261 Coadministration of Vi with anti-CD3 Ab reduces secretio

262 Finally, coadministration of virulent B. pertussis with BPZE1 did

263 Stereotaxic coadministration of VU0360172 and ACEA into the infralim

264 Coadministration of Y2 receptor agonists and GLP-1 recep

265 ing 2-h euglycemic-hyperglycemic clamps with coadministration of: 1) SU (glimepiride 1 mg) or placebo

266 evirapine-based antiretroviral therapy (ART) coadministration on levonorgestrel pharmacokinetics.

267 ence study assessed the effect of telaprevir coadministration on the pharmacokinetics of a single dos

268 und of ivermectin and azithromycin mass drug coadministration on the prevalence of scabies and impeti

269 preference and fear conditioning assays, CBD coadministration reverses these changes by downregulatin

270 In terms of antitumor efficacy, iRGD coadministration significantly augmented the individual

271 utaneous xenograft model, BEZ235 and ABT-737 coadministration significantly diminished tumor growth,

272 mor-bearing rats, with or without amifostine coadministration, via several routes.

273 mall decreases in AUC0-12 and C12 during RIF coadministration, warranting further evaluation in patie

274 EFV and RIF-based tuberculosis therapy coadministration was associated with a trend toward high

275 INH/RIF coadministration was associated with limited changes in

276 The MACV/MCV2 coadministration was common.

277 h no reduction in morphine or benzodiazepine coadministration was observed.

278 /RIF following 4 (PK2) and 12 (PK3) weeks of coadministration were evaluated.

279 mulation; this effect was abrogated by HDACI coadministration, which suggests that cells undergoing D

280 temozolomide only delayed tumor growth, its coadministration with 5-NIdR caused complete tumor regre

281 ckade produced only modest benefit; however, coadministration with a 4-1BB agonist antibody promoted

282 moted antigen-specific immune responses upon coadministration with an antigen.

283 l is to develop a TGK-specific inhibitor for coadministration with ascofuranone (AF), the most potent

284 Coadministration with boceprevir decreased RTV AUC durin

285 ne derivatives 4b and 4d may be suitable for coadministration with chloroquine against chloroquine-re

286 ed that the hypertension may be prevented by coadministration with endostatin (ES), an endogenous ang

287 Coadministration with glecaprevir and pibrentasvir did n

288 cer (CRPC), is often effective, but requires coadministration with glucocorticoids to curtail side ef

289 ecific IgG after intramuscular or intranasal coadministration with inactivated H1N1 2009 pandemic vac

290 We found that coadministration with iRGD peptide did not have an impac

291 ubcutaneously as: (1) monotherapy, (2) acute coadministration with levodopa, and (3) chronic coadmini

292 ve, MSU-mediated antitumor activity required coadministration with Mycobacterium smegmatis to induce

293 In the validation study, coadministration with oral beta-glucuronidase derived fr

294 olled trials with lapaquistat monotherapy or coadministration with other lipid-altering drugs in dysl

295 ver AZ1 against wild-type K. pneumoniae, and coadministration with outer membrane permeability enhanc

296 axis; this risk was reduced substantially by coadministration with PQ.

297 d exposure of both drugs compared with their coadministration with RTV.

298 Coadministration with steady-state telaprevir increased

299 The intravenous use of voriconazole requires coadministration with sulphobutylether-beta-cyclodextrin

300 Coadministration with telaprevir increased the terminal