ライフサイエンスコーパス: coaggregation

1 olecular interaction rather than nonspecific coaggregation.

2 ichoic acid (LTA) and a loss of intrageneric coaggregation.

3 tion of this adhesin to mediate intrageneric coaggregation.

4 sly to be involved in mediating intrageneric coaggregation.

5 der conditions that facilitated interspecies coaggregation.

6 so, what are the mechanisms underlying this coaggregation.

7 not share obvious characteristics other than coaggregation.

8 genetic components involved in mediating the coaggregation.

9 he type 2 fimbria long known for its role in coaggregation.

10 tering particles from holo-protein, implying coaggregation.

11 vel of conformational transition rather than coaggregation.

12 le SspB mediated only lactose-noninhibitable coaggregations.

13 ity of the mutation in altering intrageneric coaggregations.

14 ressively shortens pilus length and restores coaggregation accordingly, while elevated levels of shaf

15 Familial coaggregation analyses suggested that the elevated risk

16 plasmic fractionation with thermal proximity coaggregation analysis (N/C-TPCA).

17 change in their phenotypic characteristics (coaggregation and antibody reactivity) as well as in the

18 2 and Scf1 in mediating cell-cell adherence, coaggregation and biofilm formation.

19 BDII by assessing their familial aggregation/coaggregation and by assessing the coaggregation between

20 unicate through physical interactions called coaggregation and coadhesion, as well as other physiolog

21 ggregation propensity coexist in vivo, where coaggregation and cross-catalysis phenomena may affect t

22 Coaggregation and import inhibition were significantly s

23 regation of GFP-tagged NF-L protein triggers coaggregation and loss of solubility of coexpressed DsRe

24 bond formation is needed for pilus assembly, coaggregation, and biofilm formation.

25 f these interactions (called coadherences or coaggregations) are galactose sensitive.

26 le psychiatric disorders, for which familial coaggregation, as well as epidemiological and genetic ev

27 C, colony color on CHROMagar Candida medium, coaggregation assay with Fusobacterium nucleatum, and su

28 hibition of coaggregation was tested using a coaggregation assay.

29 Coaggregation assays with the sspA and sspB mutants show

30 In coaggregation assays, SspB from S. gordonii was unique i

31 ue bacteria, there are increasing reports of coaggregation between bacteria from other biofilm commun

32 specific process and that the efficiency of coaggregation between different domains decreases marked

33 The magnitude of the coaggregation between eating and mood disorders was simi

34 se and plasma lipids, whereas some exhibited coaggregation between obesity and cardiovascular disease

35 of this study was to examine the patterns of coaggregation between obligately anaerobic and oxygen-to

36 In intergeneric coaggregation between streptococci and actinomyces, type

37 tifying the genetic determinants involved in coaggregation between the 2 species.

38 gregation/coaggregation and by assessing the coaggregation between them and schizophrenia, depression

39 Here, we assessed the impact of coaggregation between two key initial colonizers of dent

40 se findings, we demonstrated that the strong coaggregation between wild-type F. nucleatum 23726 and C

41 pilins and SrtC2 produce long pili and block coaggregation by SrtA(+) bacteria.

42 th galactose, or fusobacterial-streptococcal coaggregation by the arginine homologue l-canavanine, ab

43 in assembly of these initial communities is coaggregation (cell-cell recognition by genetically dist

44 . denticola genome reveals factors mediating coaggregation, cell signaling, stress protection, and ot

45 purpose of this study was to determine oral coaggregation (CoAg) partners of C. dubliniensis and to

46 In this study, we developed a new coaggregation culture system, which supports maturation

47 Here we show that FcgammaRIIB coaggregation dampens BCR-induced BLyS receptor up-regul

48 s, were applied to study the aggregation and coaggregation effects.

49 ils to mediate interspecies interactions, or coaggregation, even though the coaggregation factor CafA

50 This protein, which we named coaggregation factor A (CafA), is one of 14 cell surface

51 eractions, or coaggregation, even though the coaggregation factor CafA is present at the pilus tip.

52 Here, we report the discovery of a key coaggregation factor for this process.

53 idogenic proteins act in synergy, with their coaggregation frequently observed in these disorders.

54 ins primarily responsible for defining these coaggregation groups and, thus, are highly significant i

55 ins have been previously classified into six coaggregation groups based on the nature of their coaggr

56 acteria onto epithelial cells and to inhibit coaggregation in a dose-dependent manner.

57 A general role for coaggregation in the formation of multi-species biofilms

58 g from intermixed communities with extensive coaggregation (including bacterial-fungal clustering) to

59 were identified as potentially regulated by coaggregation, including two phosphotransferase system t

60 that arginine biosynthesis was essential for coaggregation-induced streptococcal growth.

61 ared with the same infection with lactose as coaggregation inhibitor.

62 e functions and allowed us to detect a third coaggregation interaction with one of these organisms.

63 st bacterial surface components that mediate coaggregation interactions were used as direct immunoflu

64 ude physical cell-cell associations known as coaggregation, interspecies signaling, secretion and tur

65 Coaggregation is a process by which genetically distinct

66 Coaggregation is a well-characterized phenomenon by whic

67 40%, in other words below the level at which coaggregation is likely to be efficient.

68 we found that the Actinomyces/Streptococcus coaggregation is only abolished by deletion of cafA.

69 Coaggregation is the adhesin receptor-mediated interacti

70 We show here that FcgammaRIIB-BCR coaggregation leads to increased tyrosine phosphorylatio

71 Capsule-dependent coaggregation led to augmented invasion of Pg and may be

72 Cross-seeding or coaggregation may therefore represent an important contr

73 suggesting that bacterial interaction (i.e., coaggregation) may have inhibited the spread of the P. g

74 oteins within NAs through a mechanosensitive coaggregation mechanism.

75 precursor proteins via an extramitochondrial coaggregation mechanism.

76 IgE-FcepsilonRI coaggregation mediated by HIVgp120 or Schistosoma manson

77 Coaggregation-mediated interactions between F. nucleatum

78 esults are the first direct demonstration of coaggregation-mediated interactions during initial plaqu

79 and cells bearing different serotypes of the coaggregation-mediating streptococcal cell-surface recep

80 Focusing on the thermal proximity coaggregation method, we improved the experimental workf

81 ressing NCAM, E-, P-, N-, R-, or B-cadherin, coaggregation occurred when shear forces were low or abs

82 tudy confirms that RPS-mediated intrageneric coaggregation occurs in the earliest stages of plaque fo

83 Several studies report binding and coaggregation of Abeta and alpha-syn, yet the precise ro

84 The first phase consists of coaggregation of Abeta42 with a small amount of Abeta40,

85 ence among many oral microbes, including the coaggregation of Actinomyces oris with Streptococcus ora

86 e caused by different mutants, implying that coaggregation of an unidentified essential component or

87 Familial coaggregation of BP-II with CUD was attenuated by the in

88 Coaggregation of CD3 and CD4 reconstituted this Lck-depe

89 entral role as physical bridges that mediate coaggregation of cells and as physiological bridges that

90 We first examined the familial coaggregation of clinically diagnosed ADHD and EDs acros

91 Familial aggregation and coaggregation of CUD with mood disorders were estimated

92 This study investigated the familial coaggregation of depression and endocrine-metabolic diso

93 Data indicate that coaggregation of destabilized receptors (as few as appro

94 The familial aggregation and coaggregation of disorders were analyzed using proband p

95 ignificantly stimulates homology-independent coaggregation of dsDNA with the filament, which represen

96 l aggregation of mood disorders and familial coaggregation of eating and mood disorders.

97 n this study was to investigate the familial coaggregation of epilepsy and ADHD and to estimate the c

98 In mast cells, coaggregation of Fc gamma RIIB with the high-affinity Ig

99 Coaggregation of Fc gamma RIIB1 with B cell Ag receptors

100 2.5 (1.4-4.3; P =.001) and for the familial coaggregation of MDD with at least one other form of ASD

101 ility and aggregation of NF-L protein and to coaggregation of mutant superoxide dismutase 1 (SOD1) pr

102 ribution in flies and a rat model and led to coaggregation of NPC components and TDP-43.

103 ic and environmental factors to the familial coaggregation of OCD and suicidal behavior.

104 Familial coaggregation of OCD and suicide attempts was explained

105 is a receptor for lectin interaction in the coaggregation of oral bacteria.

106 ch is a lectin-binding receptor important in coaggregation of oral bacteria.

107 The familial coaggregation of other psychiatric disorders, in particu

108 ions on amyloid polymorphism, prion strains, coaggregation of pathogenic proteins in tissues, and mec

109 esults confirmed that GAS toxins induced the coaggregation of platelets and neutrophils, that this ac

110 diseases, such as Huntington disease, where coaggregation of poly(Q) fragments with full-length prot

111 alysis provides direct evidence for familial coaggregation of schizophrenia and BD, a finding that ar

112 This analysis revealed that coaggregation of signal-incompetent receptors prevented

113 Intrageneric coaggregation of streptococci occurs when a lectin-like

114 Coaggregation of SUDs has familial contributions, with t

115 the muscle-specific kinase MuSK and inducing coaggregation of the 43-kDa protein rapsyn with AChRs on

116 The coaggregation of the amyloid-beta peptide (Abeta) and al

117 In addition, coaggregation of the Fc gamma receptor IIB with the B-ce

118 As a counterbalance, the coaggregation of the IgG receptor FcgammaRIIB mediates i

119 n epithelial cells and that species-specific coaggregation of these bacteria correlates with this enh

120 ); however, family studies have not revealed coaggregation of these disorders.

121 tingtin, support a model of disease in which coaggregation of transcriptional components contributes

122 pplied to an example concerning the familial coaggregation of two disorders.

123 l strains accounts for the lactose-sensitive coaggregations of these bacteria with Actinomyces naeslu

124 f the model also reveals that an increase in coaggregation or reductions in integrin mobility inside

125 ased study, we aimed to clarify the familial coaggregation pattern between severe infections and OCD

126 d lower NTR accessibility leads to increased coaggregation propensity and, presumably, early cataract

127 atural host, we constructed and analyzed the coaggregation properties of an isogenic sspB mutant of S

128 ion with streptococci but retained wild-type coaggregation properties with other genera of bacteria.

129 or defined media, surface hydrophobicity, or coaggregation properties.

130 -binding protein Hsa, and the hydrophobicity/coaggregation proteins CshA and CshB.

131 ing intermediates rather than by nonspecific coaggregation, providing a rationale for recovering rela

132 ponds more to trapping by cross-reaction and coaggregation rather than classical seeding and growth.

133 of Streptococcus gordonii 38 functions as a coaggregation receptor for surface adhesins on other mem

134 of serotype 10F Streptococcus pneumoniae and coaggregation receptor polysaccharide (RPS) of Streptoco

135 The antigenically related coaggregation receptor polysaccharides (RPS) of Streptoc

136 The coaggregation receptor polysaccharides (RPS) of Streptoc

137 presence of L-rhamnose (Rha) branches in the coaggregation receptor polysaccharides (RPS) of Streptoc

138 The streptococcal coaggregation regulator (ScaR) of Streptococcus gordonii

139 sed to insertionally inactivate the putative coaggregation-relevant gene in DL1.

140 Tn916 was used to insertionally inactivate a coaggregation-relevant locus of Streptococcus gordonii D

141 Evidently, coaggregation requires proper positioning of the tip adh

142 Cocultures without induced coaggregation showed similar regulation.

143 SspA exhibited two coaggregation-specific functions.

144 of chimeric protein constructs revealed that coaggregation specificity was determined by sequences wi

145 In intrageneric coaggregation, streptococci such as Streptococcus gordon

146 arily correlate with a lack of cross-species coaggregation, suggesting that species-specificity of pr

147 The pattern of familial coaggregation suggests familial liability for the associ

148 t, mixing of IAPP and aS monomers results in coaggregation that is faster than either protein alone;

149 Subsequent to FcgammaRIIB/BCR coaggregation, the survival promoting actions of BLyS ar

150 ans streptococci participate in intrageneric coaggregations, the cell-to-cell adherence among genetic

151 than about 70% identity are highly prone to coaggregation, those with less than 30-40% sequence iden

152 Here, we use thermal proximity coaggregation (TPCA) mass spectrometry to characterize t

153 without coaggregates showed no growth until coaggregation was evident (9 h).

154 n epithelial cell culture, and inhibition of coaggregation was tested using a coaggregation assay.

155 Two genes relevant to these intrageneric coaggregations were identified by transposon Tn916 mutag

156 at CafA or an antibody against CafA inhibits coaggregation, whereas the shaft protein FimA or a polyc

157 infection, the capsule also participates in coaggregation, which may lead to characteristic virulenc

158 opathology, and inhibition of beta(2)M-Abeta coaggregation with a beta(2)M-based blocking peptide ame

159 However, within 1 h after coaggregation with A. naeslundii, the expression of argC

160 ated aggregation by gp340 but did not affect coaggregation with A. naeslundii.

161 ccus gordonii genes regulated in response to coaggregation with Actinomyces naeslundii.

162 icant FcgammaRIIB1 phosphorylation following coaggregation with B cell Ag receptor.

163 id pathology independent of MHC class I, and coaggregation with beta(2)M is essential for Abeta neuro

164 Similarly, familial coaggregation with death by suicide was attributed to ad

165 his report we demonstrate that Fc gamma RIIB coaggregation with Fc epsilon RI stimulates enhanced SHI

166 All the other AgI/II polypeptides mediated coaggregation with group C and group D strains of A. nae

167 ental ability to participate in intergeneric coaggregation with human oral actinomyces, indicating th

168 spB from S. gordonii was unique in mediating coaggregation with only group A and group E strains of A

169 of type 2 fimbriae that directly facilitate coaggregation with oral streptococci and Actinomyces bio

170 n adherence to salivary proteins and mediate coaggregation with other bacteria.

171 ies, and MDD displays a significant familial coaggregation with other forms of ASD, taken collectivel

172 D phenotype transmission across families and coaggregation with other major psychiatric disorders.

173 mutants failed to show galactose-inhibitable coaggregation with Porphyromonas gingivalis and were def

174 ata indicate that responses of V. parvula to coaggregation with S. gordonii are dominated by oxidativ

175 Insertion mutants showed altered coaggregation with streptococci but retained wild-type c

176 es species biofilm development and bacterial coaggregation with streptococci.

177 not participate in type 2 fimbriae-mediated coaggregation with Streptococcus oralis 34.

178 strain ATCC 35405 to HEp-2 cell cultures and coaggregation with Tannerella forsythensis were attenuat

179 nd penetration of human epithelial cells and coaggregation with Tannerella forsythensis.

180 d C. tropicalis), CSH status correlated with coaggregation with the anaerobic oral bacterium Fusobact

181 signals after B cell antigen receptor (BCR) coaggregation with the low affinity Fc receptor, it is n

182 trains that participate in lactose-sensitive coaggregations with actinomyces was examined.

183 regation groups based on the nature of their coaggregations with S. gordonii DL1 and other oral strep

184 harides also participate in GalNAc-sensitive coaggregations with strains of Streptococcus gordonii an