ライフサイエンスコーパス: coarse

1 His hair was sparse and coarse.

2 on-level representational invariance remains coarse.

3 fine (spatial period of 320-580 micron) and coarse (1520-1920 micron) ranges using static pressing o

4 ited pH measurements for fine (<2.5 mum) and coarse (2.5-10 mum) particles.

5 missions as the gas phase, fine aerosol, and coarse aerosol.

6 includes separate compartments for fine and coarse aerosols and the gas phase and study its sensitiv

7 These results demonstrate that coarse air PM induces dose-dependent inflammatory respon

8 in reconstructed human epidermis exposed to coarse air PM.

9 and AhR expression of epidermis treated with coarse air PM.

10 ific wood container without making it appear coarse and astringent.

11 ification (AG versus LG), which enabled both coarse and fine adjustments in solution and proteome act

12 order of Legendre polynomial expansions, and coarse and fine mesh grid.

13 trix covering a large expanse of DNA at both coarse and fine resolution.

14 n importance due to its capacity to use both coarse and fine scale patterns of brain activity.

15 patial distribution and habitat selection at coarse and fine scales.

16 considerable myofibrillar alterations with a coarse and irregular intermyofibrillar network.

17 In this research, coarse and nano emulsions of citral were prepared and em

18 Florida during the past 2000 years based on coarse anomaly event detection from two coastal lacustri

19 and predict these liquid dynamics, based on coarse approximate simulations of fluids as collections

20 gh-throughput chemical screens typically use coarse assays such as cell survival, limiting what can b

21 tes of the mitigation potential are based on coarse assessments of both agricultural extent and above

22 rtensite grains (<500 nm) sandwiched between coarse austenite grains (~10 um).

23 s) (SSF = 2, fine; SSF = 4, medium; SSF = 6, coarse) by using specialized software; values of these p

24 l exposure to NO(2), PM(10), PM(2.5), and PM(coarse) (calculated by subtracting PM(2.5) from PM(10))

25 led causal information for a few domains and coarse causal models embedding markers indicating that t

26 We find that increasing the area under coarse cereals (i.e., millets, sorghum) improves nutriti

27 ility of switching cropped area from rice to coarse cereals.

28 Temporally and spatially coarse data have clear benefits in terms of reduced mode

29 greatly expand the fundamentally limited and coarse data that could be collected using location-only

30 and retain consistency at large scales with coarse data.

31 , the grains were significantly refined from coarse dendrites of hundreds of micrometers to fine equi

32 ndance of a protein at the cell surface is a coarse descriptor entwined with changes in local nanosca

33 d with the gelatinization was the fastest in coarse dough, where it gained also the highest peak visc

34 ile plants and AM fungi respond similarly to coarse environmental filters, most variation remains une

35 MMSE to the original 30-point version using coarse equipercentile equating methods that preserved di

36 s that have both an exposure biomarker and a coarse external measure of exposure to a treatment.

37 d individuals showed facial dysmorphism with coarse face, upslanted palpebral fissures, broad nasal t

38 nn-Laband syndrome (ZLS) is characterized by coarse facial features with gingival enlargement, intell

39 s characterized by developmental disability, coarse facial features, and fifth digit/nail hypoplasia

40 tter to soil increased the capability of the coarse fraction (FSa) to stabilize organic carbon, thus

41 grass designation, minimum annual LAI, soil coarse fragment volume) rather than climatic variables s

42 ow that an analysis approach tailored to the coarse grain features of the dynamics is able to reveal

43 In both approaches, we deliberately coarse-grain a new clickstream proprietary dataset to pr

44 A coarse-grain computational method integrates biophysical

45 Coarse-grain molecular dynamics simulations reveal that

46 and cholesterol clustering by cav-1 by using coarse-grain molecular dynamics simulations.

47 gene expression(1-3), but these measurements coarse-grain over the individual copies of the gene, whe

48 ach to simultaneously capture both fine- and coarse-grain patterns of variability.

49 Here, we use coarse-grain simulation to study three scenarios, all re

50 In this study, we performed coarse grained (CG) molecule dynamics (MD) simulations o

51 Wear rates in the initially soft (coarse grained) material were shown to be remarkably low

52 ongoing development of a largely "bottom-up" coarse-grained (CG) model of the SARS-CoV-2 virion.

53 Our previous work used a coarse-grained (CG) model to simulate the action of F(0)

54 Here, we introduce a set of machine-learned coarse-grained (CG) models (ML-BOP, ML-BOP(dih), and ML-

55 sentations that correspond to particle-based coarse-grained (CG) models for a simple microscopic mode

56 Here, we present a coarse-grained (CG) simulation method that enables micro

57 Coarse-grained (CG) simulations of ESCRT assembly at HIV

58 ne interactions and function, we carried out coarse-grained and all-atom molecular dynamics simulatio

59 Here, we used a combination of coarse-grained and all-atom molecular dynamics simulatio

60 Using coarse-grained and atomistic simulations, we study vario

61 uantitative scoring approaches, however, are coarse-grained and lack precise neuroanatomic localizati

62 use a silent lip-read signal to synthesize a coarse-grained auditory speech representation in early a

63 To this end, we developed a coarse-grained bead-and-spring model and investigated it

64 inverse Brownian dynamics method based on a coarse-grained bead-spring chain model has been proposed

65 ations (or in silico experiments) of generic coarse-grained bead-spring polymer chains in an implicit

66 static or dynamic selection of atoms or even coarse-grained beads for the density calculation.

67 overlapping, variable-length segments (i.e., coarse-grained beads) for each component protein sequenc

68 ract mechanical parameters for inputs into a coarse-grained biophysical polymer model that successful

69 obably all quasibrittle materials, including coarse-grained ceramics, rocks, stiff foams, fiber compo

70 We use a coarse-grained computational model to capture nanotube l

71 Here, we develop a minimal coarse-grained computational model to identify the physi

72 er adhesion assembly, we therefore develop a coarse-grained computational model.

73 Our results are gained from coarse-grained computer simulations and first-principles

74 rstanding recently revealed by atomistic and coarse-grained computer simulations of nanoscale process

75 of principle, we apply torsional forces to a coarse-grained continuum model of the antibody protein i

76 h a high loading (10 kg/m(2) ) of relatively coarse-grained crushed basalt significantly increased th

77 size and complexity, but here we argue that coarse-grained data introduce errors that, in biological

78 Our model, which is based on a coarse-grained description of ligands and solvent effect

79 In this work, we pursue a coarse-grained description of these systems by proposing

80 ore slowly than the generation time (i.e., a coarse-grained environment) a population will not experi

81 tead, we propose that adaptive plasticity in coarse-grained environments evolves as a by-product of i

82 ndeavoring toward a transferable, predictive coarse-grained explicit-chain model for biomolecular con

83 beta(3), we developed a modified form of the coarse-grained heterogeneous elastic network model (hENM

84 Based on a predictive coarse-grained IDP model, we identified a region of the

85 Using coarse-grained kinetic Langevin dynamics, we performed c

86 We are able to relate each more coarse-grained level to a finer one, which allows us to

87 d phase separation in model membranes at the coarse-grained level, but atomistic simulations remain c

88 Pegmatites are shallow, coarse-grained magmatic intrusions with crystals occasio

89 features to train the models in a simple and coarse-grained manner.

90 ed or unfolded, and were directly taken from coarse-grained MD simulations.

91 ned with simulations based on a transferable coarse-grained model allows us to predict accurately the

92 tative agreement with the predictions of our coarse-grained model as well as qualitative agreement wi

93 n Dry Martini, an efficient implicit solvent coarse-grained model for lipids, and the Lattice Boltzma

94 ics simulations and a previously established coarse-grained model having each residue represented by

95 We used a simple whole-cell coarse-grained model of cell physiology that combines th

96 We use a coarse-grained model of DNA to study the kinetics and th

97 ing in EMT and drug resistance, we analyze a coarse-grained model of phenotypic switching between two

98 rowth laws are discussed in the context of a coarse-grained model of phototrophic growth and availabl

99 A coarse-grained model of SUHI coupled with a stochastic s

100 erimental observations using a parameterized coarse-grained model of VWF.

101 s somewhat counterintuitive idea in a simple coarse-grained model results in the prediction that ther

102 Recently, Brownian dynamics simulations of a coarse-grained model system reproduced protracted pausin

103 Using a minimal coarse-grained model that allows us to simulate thousand

104 We generate a bottom-up coarse-grained model that demonstrates similar membrane-

105 rform molecular dynamics simulations using a coarse-grained model that includes a 1/r(4) potential fo

106 We introduce a coarse-grained model that links population, background c

107 Our study used homology modeling and a coarse-grained model to generate all of the possible "en

108 We use the oxDNA coarse-grained model to provide a detailed characterizat

109 We developed a mesoscale coarse-grained model to study the characteristics of tra

110 Here, we develop a coarse-grained model to systematically explore the effec

111 Here, we use a coarse-grained model to systematically study how variati

112 We develop a coarse-grained model which connects statistical features

113 nd demonstrated by computer simulations of a coarse-grained model.

114 possibilities for future improvements of the coarse-grained model.

115 such as proteins and protein complexes with coarse-grained modeling and simulations.

116 Alternative coarse-grained modeling must also incorporate appropriat

117 Coarse-grained modeling of conjugated polymers has becom

118 e DNA/RNA nanostructures simulated using the coarse-grained modeling tool, oxDNA, which has grown in

119 Further, experiments and coarse-grained modelling showed the substrate alone freq

120 to study the crystallization of a family of coarse-grained models of chiral molecules with a broad r

121 model to be broadly applicable and useful in coarse-grained models of gas transport in metals.

122 as proven to be a valuable tool to determine coarse-grained models of membrane-embedded Bcl-2 protein

123 In this work, we study coarse-grained models of organic glass formers containin

124 More specifically, we developed two coarse-grained models of proteins, which interact identi

125 Both FD-AFM and computational studies on coarse-grained models of rhodopsin revealed that the act

126 l implementations entail compromises between coarse-grained models of the spin label that lower the r

127 ows the assessment of the limitations of the coarse-grained models proposed.

128 ting from these strategies have been used in coarse-grained models to predict light-dependent growth

129 tematic experiments and simulations based on coarse-grained models to show that the collective intera

130 Consequently, it can produce most economical coarse-grained models while faithfully preserving the sh

131 Importantly, these coarse-grained models, while only calibrated based on bi

132 nslation that are difficult to study in more coarse-grained models.

133 Here, we use coarse-grained molecular dynamics (MD) simulation and su

134 Results of coarse-grained Molecular Dynamics (MD) simulations of no

135 mensional structure folding model with IsRNA coarse-grained molecular dynamics 3D folding simulations

136 By combining coarse-grained molecular dynamics and newly developed ac

137 R toxicity, a one-bead-per-amino-acid (1BPA) coarse-grained molecular dynamics model is used to study

138 First, a computational modeling approach by coarse-grained molecular dynamics simulation of the whol

139 Using native mass spectrometry, coarse-grained molecular dynamics simulations and functi

140 We present coarse-grained molecular dynamics simulations of monomer

141 Here, we report the results of coarse-grained molecular dynamics simulations of monomer

142 Coarse-grained molecular dynamics simulations of the HTL

143 Indeed, initial coarse-grained molecular dynamics simulations of the lon

144 Coarse-grained molecular dynamics simulations reveal tha

145 We used coarse-grained molecular dynamics simulations to charact

146 Here we use coarse-grained molecular dynamics simulations to investi

147 Here, using coarse-grained molecular dynamics simulations validated

148 bined with umbrella-sampling simulations and coarse-grained molecular dynamics simulations, we are ab

149 Using coarse-grained molecular dynamics simulations, we explor

150 With atomistic and coarse-grained molecular dynamics simulations, we resolv

151 Using coarse-grained molecular dynamics simulations, we show t

152 esence of MG2a and L18W-PGLa to all-atom and coarse-grained molecular dynamics simulations.

153 The combination of coarse-grained molecular dynamics studies and NMR should

154 g the new technique are analyzed by means of coarse-grained molecular simulations and experimentally

155 Here, using coarse-grained molecular simulations and statistical mec

156 to the binding of multiple chaperones using coarse-grained molecular simulations.

157 Coarse-grained network modeling demonstrated that an abr

158 We employ both coarse-grained node dropout and fine-grained edge dropou

159 In particular, coarse-grained node dropout can efficiently and systemat

160 semble through a Monte Carlo simulation of a coarse-grained nucleosome model with sequence-dependent

161 ndom forest to learn a parameterization from coarse-grained output of a three-dimensional high-resolu

162 Using a coarse-grained particle-network model, we first establis

163 5) The model provides a coarse-grained phenomenological description of diffusion

164 We show that all primary, coarse-grained platy calcitic lateral walls are covered

165 identify the heterogenous dynamics of model coarse-grained polymer chains both in 'bulk' and near th

166 Using coarse-grained polymer theory and numerical simulations,

167 Here, we present a coarse-grained polynucleotide model developed to fill th

168 spectral data as input in the refinement of coarse-grained potentials.

169 del underlying the server's predictions is a coarse-grained protein force field which has its roots i

170 In this work, a predictive coarse-grained protein force field, the associative memo

171 Here, using a coarse-grained protein model, molecular dynamics (MD) si

172 e the level of sensitivity of spectra to the coarse-grained representation back-mapping protocol.

173 ams for multicomponent systems comprising of coarse-grained representations of multivalent proteins.

174 spectra of conjugated polymers directly from coarse-grained representations while avoiding repetitive

175 Coarse-grained rules are widely used in chemistry, physi

176 viding strong evidence for the prediction of coarse-grained semantic features that goes beyond the pr

177 ubules, with diameters of about 30 nm, carry coarse-grained Shannon information to the centrosome adj

178 escribe the development and application of a coarse-grained simulation approach that addresses these

179 We review atomistic and coarse-grained simulation studies of amyloid peptides in

180 Here, we use theoretical modeling and coarse-grained simulation to explore the interplay betwe

181 Coarse-grained simulations employing native centric mode

182 Although the MARTINI coarse-grained simulations give the correct free energy

183 wer these questions in the affirmative using coarse-grained simulations of the self-organized polymer

184 ted in the covalent network was predicted by coarse-grained simulations of the system's chemical stru

185 All-atom and coarse-grained simulations reproduced some of the experi

186 physical parameters for this process and use coarse-grained simulations with explicit cross-linkers t

187 Using elasticity theory and coarse-grained simulations, we analyze the conditions re

188 e these results to those obtained by MARTINI coarse-grained simulations.

189 ng approach, combining a previously reported coarse-grained small-scale proteome allocation model wit

190 Here, we present a simple, coarse-grained statistical model of niche construction c

191 (ii) an efficient approach for FRET-assisted coarse-grained structural modeling, and all-atom molecul

192 echanism of domain swapping of M(pro)C using coarse-grained structure-based models and molecular dyna

193 terials, a rigorous bridge between simulated coarse-grained structures and spectroscopy has not been

194 s of Azoarcus ribozyme, based on an accurate coarse-grained three-site interaction model with explici

195 procedures such as ad hoc back-mapping from coarse-grained to atomistic representations followed by

196 RAG uses coarse-grained tree graphs to represent RNA secondary st

197 nct minima of a Ginzburg-Landau functional-a coarse-grained version of the elastic energy, which pena

198 Coarse-grained volcanic ash leads to significantly highe

199 illance data, which are far sparser and more coarse-grained, achieve only 56% sensitivity.

200 NA-vWF interaction by integrating atomistic, coarse-grained, and Brownian dynamics simulations, with

201 roduce a filament-based simulation model for coarse-grained, effective motor-mediated interaction bet

202 we have employed the elastic folder model, a coarse-grained, minimalistic representation of the polyp

203 l strategies with variable discretization or coarse graining and unbinding dynamics, and although gen

204 ial tradeoffs associated with the process of coarse graining NMMII ensembles and highlight the robust

205 Coarse graining of these ensemble types from two sets of

206 mechanics, allowed better contractility with coarse graining, though connectivity was still markedly

207 markedly reduced for this ensemble type with coarse graining.

208 n protocol which decreases the resolution by coarse-graining and averaging over short similarity dist

209 Retraining for different coarse-graining factors shows the parameterization perfo

210 monstrate the orchestration of various novel coarse-graining methods by applying them to the mitotic

211 ar systems can greatly benefit from a set of coarse-graining methods that, ideally, can be automatica

212 ian-Langevin dynamics principles to derive a coarse-graining multiscale myofilament model that can de

213 his functional coordinate system, permitting coarse-graining of microbiomes in terms of ecological ni

214 n is progressively decreased by hierarchical coarse-graining of the anatomical regions.

215 rge problems, we also develop an approximate coarse-graining procedure that avoids the need for negat

216 lations suggest an emergent length scale for coarse-graining proteins, as well as a qualitative disti

217 allows us to relate model parameters between coarse-grainings and which provides a more precise meani

218 A sequence of manual and automatic coarse-grainings finally leads to the coarsest determini

219 t or flour is sparse compared to the flow of coarse, granular media like sand.

220 itself is viewed, and is less present at the coarse granularity of visual transitions between leads.

221 d appearance of greyscale representations of coarse gratings and a range of everyday images.

222 However, BMI is a coarse health measure and risks associated with BMI may

223 al scales of months to years, providing only coarse indications of trophic level(s).

224 esponse to blood loss is limited, in part by coarse interpretation of blood measurements.

225 This correlates with coarse irregular SEI clumps at formation, 3D potassium i

226 ution of existing land cover datasets is too coarse, large-scale land cover changes in the Arctic-Bor

227 Despite being similar at a coarse level, mouse and human teeth reveal molecular dif

228 ich category-selective regions are part of a coarse map of object space whose dimensions can be extra

229 s may result in the preferential delivery of coarse material to channel networks that initiate debris

230 en mode particles, and underestimated in the coarse mode.

231 ngth, elasticity and Young modulus) than the coarse ones.

232 From the coarse particle concentration record we infer the East G

233 Coarse particulate matter with aerodynamic diameter betw

234 values for natural particles (e.g., fine and coarse particulate organic matter) showed that particle

235 y-wide concentrations of PM(10), PM(2.5), PM(coarse) (particulate matter >2.5-10 mum diameter), nitro

236 oward detecting changes in ambient light and coarse patterns rather than fine details.

237 g to bean genotype and powder particle size: coarse powders resulted in larger (+26%) and thinner (-1

238 our study provides a rationale for employing coarse Raman mapping to substantially reduce measurement

239 s molecular specificity, we demonstrate that coarse Raman microscopy is capable of rapidly mapping a

240 ents except when pressing on surfaces in the coarse range.

241 liding than pressing in the fine but not the coarse range.

242 Consistent with spatially coarse receptive fields in vLGN, visually evoked changes

243 Due to the coarse resolution provided by sampling with plankton net

244 ameterization leads to stable simulations at coarse resolution that replicate the climate of the high

245 sure and elevation) were determined from the coarse-resolution climate surfaces using thin-plate spli

246 matic changes rely on seasonally aggregated, coarse-resolution data.

247 pted at continental or global scales and use coarse-resolution models, which suffer from severe syste

248 ield measurement limitations and reliance on coarse-resolution satellite data.

249 , despite isometric scaling between stem and coarse root production, fine root production scales agai

250 tterns; and (3) mature lianas had shallowest coarse roots and evergreen trees had the deepest.

251 rate up to 13 cm into sediment consisting of coarse sand, fine gravel, and medium gravel.

252 as filtered through a mixture of zeolite and coarse, sand-sized crystalline quartz.

253 On a coarse scale, the genome is divided into euchromatin, wh

254 At the coarse scale, we found no correlation between percent de

255 em in the open ocean, but their map sense is coarse scale.

256 fine level of detail rather than merely at a coarse scale.

257 However, the coarse-scale data typically used in biogeographic studie

258 abitat descriptors indicate that focusing on coarse-scale metrics alone may mask fine-scale ecologica

259 ecreases in contralateral theta (4-7 Hz) and coarse-scale MSE (slow activity), and increases in peril

260 Our results are consistent with coarse-scale niche conservatism at the clade level and s

261 However, coarse-scale population indices from northern US breedin

262 Residents showed stronger coarse-scale selection for terrain associated with preda

263 Nevertheless, the analyses are restricted to coarse-scale signals and should be considered with cauti

264 our review on the environmental conditions (coarse-scale variables) that shape the life-history trai

265 nvironmental studies describe microbiomes at coarse scales of taxonomic resolution (bacterial communi

266 onses to climate change typically operate at coarse-scales (1km(2)-0.5 degrees ) at which fine-scale

267 species is based on morphological traits and coarse sets of genetic markers.

268 und on the surface of sediment consisting of coarse silt and fine sand, while the particles might inf

269 e field mapping, we revealed the presence of coarse somatotopy along the mediolateral axis in PPC.

270 trajectories exploit a mapping to a mesh in coarse space and allow for efficient calculations of kin

271 te-induced growth that are not observable in coarse spatial resolution (e.g., 500 m or greater pixel

272 Globally, the coarse spatial resolution of ESMs and their inability to

273 ever, small-animal PET imaging is limited by coarse spatial resolution.

274 ents long-term average thermal conditions at coarse spatial resolutions only.

275 re are provided by satellite sensors, but at coarse spatial resolutions.

276 ieved with relatively few sensors (< 100) at coarse spatial samplings (~ 30 mm) at high SNR.

277 n measuring this organization with fMRI at a coarse spatial scale, the activity patterns for flexion

278 s, whereas the visual periphery is tuned for coarse spatial scales, in line with the naturally occurr

279 representing soil carbon dynamics at fine to coarse spatial scales.

280 risk posed by measuring vaccination rates at coarse spatial scales.

281 per disparity limit predicts the presence of coarse stereopsis in humans with macular degeneration (M

282 Nevertheless, some individuals with MD have coarse stereopsis that is useful for eye-hand coordinati

283 duals with MD (n = 25, male and female) have coarse stereopsis when the distance between intact retin

284 ironmental and cultural variables, including coarse substrate, stabilized sea surface temperature, an

285 gions of interest have been used to generate coarse summaries of mesoscale projectomes.

286 rticles of pea and normal maize RS3 showed a coarse surface and irregular shapes and sizes.

287 ld be obscured in shorter-term or temporally-coarse surveys.

288 a continuum in their sensitivity to fine vs. coarse texture, and neurons at the extrema of this conti

289 l as intensity variations, fine-texture, and coarse-texture of the pulmonary tissue.

290 face texture, but previous studies used only coarse textures, which span a restricted range of tangib

291 ipulating neural activity in monkeys are too coarse to address many of the outstanding questions in p

292 derived from weather stations are often too coarse to capture the conditions experienced by organism

293 reported at the state-level-a resolution too coarse to detect community-level clustering of nonvaccin

294 se from a three-dimensional (3D) U-Net and a coarse-to-fine deep learning method.

295 he 3D U-Net method and 0.52 +/- 0.17 for the coarse-to-fine method (P < .0001).

296 ed before identity information, suggesting a coarse-to-fine processing of face dimensions.

297 epresentation of the object proceeded from a coarse-to-fine resolution.

298 ecording of cell migrations provides a first coarse view of what the human PS may resemble in vivo.

299 In reburns, coarse wood biomass and aboveground carbon stocks were r

300 two locations were milled to obtain fine and coarse wrinkled (WPF) and round pea flour (RPF).