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1 y of cocaine in brain and plasma relative to cocaethylene.
2                               Preexposure to cocaethylene (15 or 25 mg/kg) significantly enhanced the
3                                              Cocaethylene, a metabolite of cocaine and alcohol, is a
4 A similar rate is observed for hydrolysis of cocaethylene, a more potent cocaine metabolite that has
5 d using cocaine and two cocaine metabolites, cocaethylene and benzoylecgonine, which also bind with n
6 e-dependent decrements in CAP amplitude, but cocaethylene and isopropylcocaine at medium to high conc
7 erve impulse blockade by lidocaine, cocaine, cocaethylene and isopropylcocaine using rat sciatic nerv
8 he active cocaine metabolites norcocaine and cocaethylene and its inability to hydrolyze benzoylecgon
9 activating mutant channel to close, trapping cocaethylene and slowing the recovery.
10 aine and potent cocaine derivatives, such as cocaethylene, and for additional humanization of the ant
11  Cocaine, ecgonine methyl ester, norcocaine, cocaethylene, and mephedrone were mainly transformed by
12 estigated the local anesthetic properties of cocaethylene as well as isopropylcocaine, another potent
13 t additional mechanisms, such as more stable cocaethylene binding, may be a more important determinan
14 h an important role for fast inactivation in cocaethylene binding.
15                                              Cocaethylene caused an inhibition of dopamine synthesis
16                                              Cocaethylene-induced behaviors were significantly less i
17 ivation slow the recovery and potentiate the cocaethylene inhibition of the Nav1.5 channel by distinc
18                         A rapid component of cocaethylene inhibition was observed in a noninactivatin
19 iminated rapid inactivation and weakened the cocaethylene inhibition, consistent with an important ro
20 56C mutation did not alter the recovery from cocaethylene inhibition.
21                                              Cocaethylene is a naturally occurring cocaine derivative
22 n, and ability to hydrolyze both cocaine and cocaethylene make cocE an attractive candidate for rapid
23 ocomotor activity was not observed following cocaethylene preexposure.
24  candidates, and suggest a mechanism whereby cocaethylene produces a decreased euphoria in humans com
25                                              Cocaethylene produces minimal tonic block under resting
26    The present study assessed the ability of cocaethylene to induce sensitization to the behavioral a
27  the behavioral and neurochemical effects of cocaethylene treatment in Long-Evans (LE) and Sprague-Da
28   Serotonin synthesis was also suppressed by cocaethylene treatment, however this phenomenon was less
29 l, suggesting that this mutation facilitates cocaethylene untrapping, which seems to be the rate-limi
30            DM-CocE hydrolyzes norcocaine and cocaethylene with 58 and 45% of its catalytic efficiency
31 t the aptamer binds cocaine, norcocaine, and cocaethylene with similar affinities and aminoglycosides