ライフサイエンスコーパス: cochlear duct

1 r cell differentiation within the developing cochlear duct.

2 on of ectopic sensory patches underneath the cochlear duct.

3 sh sensory and nonsensory territories in the cochlear duct.

4 is vestibular-like hair cells located in the cochlear duct.

5 paracrine Wnt signaling predominates in the cochlear duct.

6 ause of displaced hair cells and a shortened cochlear duct.

7 circular canals, and a malformed saccule and cochlear duct.

8 e down-regulated in the other regions of the cochlear duct.

9 neither a vestibular apparatus nor a coiled cochlear duct.

10 essed in adjacent, nonsensory regions of the cochlear duct.

11 ve rise to ectopic vestibular patches in the cochlear duct.

12 aintain sensory/nonsensory boundaries in the cochlear duct.

13 roperties of the basilar membrane within the cochlear duct.

14 gamma are initially expressed throughout the cochlear duct.

15 nating mosaic that extends the length of the cochlear duct.

16 were more susceptible to RA effects than the cochlear duct.

17 s at frequency-dependent positions along the cochlear duct.

18 single pool of prosensory progenitors in the cochlear duct.

19 ducts and semicircular canals and have short cochlear ducts.

20 cells (Sox2-EGFP(-)) from E12, E14.5 and E16 cochlear ducts.

21 inner ear development including a shortened cochlear duct, a decrease in the total number of cochlea

22 Ventral otic derivatives including the cochlear duct and cochleovestibular ganglia failed to de

23 ed to absence of the kinocilium, a shortened cochlear duct and flattened hair bundle morphology.

24 ells, and Reissner's membrane throughout the cochlear duct and had complete inner and outer hair cell

25 rosensory domain that runs the length of the cochlear duct and is bounded by two nonsensory domains,

26 cochlear epithelium resulted in a shortened cochlear duct and misoriented and misshapen hair bundles

27 tly, ventral otic derivatives, including the cochlear duct and saccule, fail to form, and dorsal otic

28 By contrast, the formation of the proximal cochlear duct and saccule, which requires less Shh signa

29 cts in differentiation and patterning of the cochlear duct and sensory epithelium and loss of the dor

30 Frzb (SFRP3) is confined to the nonsensory cochlear duct and the lagena macula, whereas SFRP2 is ma

31 egulating the differential growth within the cochlear duct and thus, its proper outgrowth and coiling

32 ranscripts were both widely expressed in the cochlear duct and utricle in an overlapping pattern, sug

33 of Corti and to electrical potentials in the cochlear ducts and outer hair cells (OHC).

34 ation of vestibular formation, length of the cochlear duct, and the number of cochlear hair cells.

35 ory domain that lies along the length of the cochlear duct, and which forms before the onset of hair

36 the sensory and secretory epithelium of the cochlear duct appear normal in the Hmx3 null animals.

37 Tight junctions in the cochlear duct are thought to compartmentalize endolymph

38 ithelial tissues, including cells lining the cochlear duct, at embryonic day 18.5 and postnatal day 5

39 regionalization, convergent extension of the cochlear duct, cell fate specification, synaptogenesis,

40 Wnt5a and Wnt7b are redundantly required for cochlear duct coiling and elongation, HC planar polarity

41 The lateral nonsensory cochlear duct continuously expresses Frzb and temporaril

42 ng conducted over the time course of chicken cochlear duct development reveals that Wnt-related gene

43 found in the same post-mitotic region of the cochlear duct during early stages of cochlear developmen

44 oping auditory sensory epithelium to control cochlear duct elongation and planar polarity of resident

45 ature semicircular canals, utricle, saccule, cochlear duct, endolymphatic duct and sac, and neurons o

46 Epithelial sensory precursors within the cochlear duct first undergo terminal mitosis before diff

47 s with shifted rhombomeres showed defects in cochlear duct formation indicating that signaling from r

48 Removal of rhombomere 5 affects cochlear duct growth, while rhombomere 6 removal affects

49 The avian cochlear duct houses both a vestibular and auditory sens

50 t Id1, Id2, and Id3 are expressed within the cochlear duct in a pattern that is consistent with a rol

51 n expression to the prosensory region of the cochlear duct including Sox2, Isl1, Eya1 and Pou4f3.

52 cochlea, as inhibiting the outgrowth of the cochlear duct increases the number of Atoh1-lineage cell

53 The cochlear duct is exclusively endowed with endocochlear p

54 utcome of the intricate K+ regulation in the cochlear duct is the endocochlear potential (EP), approx

55 The stria vascularis (StV) of the cochlear duct is the station where the EP is generated,

56 horn (aka ear trumpet), the geometry of the cochlear duct manifests tapering symmetry, a felicitous

57 ve severe vestibular defects and a shortened cochlear duct, markers of the prosensory domain appear a

58 ound that cells and tissue components of the cochlear duct may be labelled by fluorescent markers wit

59 -dependent regulatory mechanisms involved in cochlear duct morphogenesis and establishment of its con

60 along the anteroposterior axis also impacts cochlear duct morphogenesis but has little effect on the

61 associated regulatory sequences that promote cochlear duct morphogenesis.

62 lial PCP and for convergent extension of the cochlear duct of Mus musculus.

63 rphogenesis of the auditory subdivision, the cochlear duct, or basilar papilla.

64 e inner ear is distorted and malformed, with cochlear duct outgrowth and coiling most affected.

65 Pax2 affects tissue specification within the cochlear duct, particularly regions between the sensory

66 ng from rhombomeres 5 and 6 is important for cochlear duct patterning in both chicken and mice.

67 omotes ventral fates such as the saccule and cochlear duct, possibly by restricting Otx2 expression.

68 thin the prosensory domain of the developing cochlear duct relies on the temporal and spatial regulat

69 e lineage of Atoh1-positive cells within the cochlear duct remains unclear.

70 ytes into the future stria vascularis of the cochlear duct requires c-MET signaling.

71 of the ventral-most otic region, the distal cochlear duct, requires robust Gli2/3A function.

72 cifically in the Sox2-positive domain of the cochlear duct, resulting in down-regulation of Tead gene

73 RT-PCR on whole cochlear ducts suggested that this short variant is less

74 ferents extend hundreds of microns along the cochlear duct to contact many outer hair cells.

75 um had doubled in size but the length of the cochlear duct was unaffected.

76 e RAR and RXR receptors within the embryonic cochlear duct were determined by in situ hybridization.

77 ne of the known exceptions in mammals is the cochlear duct, where the potential is approximately 80-1

78 pillar cells) along the entire length of the cochlear duct, with the most extreme abnormalities found

79 nd resulted from an efficient packing of the cochlear duct within the petrous bone.