ライフサイエンスコーパス: collagen type I

1 of HSP47 to bind KDELR2 and dissociate from collagen type I.

2 ineralization upon elastic energy storage in collagen type I.

3 ution of DDR1 following its interaction with collagen type I.

4 ial cell adhesion and migration on fibrillar collagen type I.

5 equency, expression of fibronectin ED-A, and collagen type I.

6 eta1 and reduced apoptosis in cells grown on collagen type I.

7 des containing robotically printed arrays of collagen type I.

8 broblasts, plate-immobilized fibronectin, or collagen type I.

9 to mimic the site of a lethal OI mutation in collagen type I.

10 n stroma formation, including TGF-beta-1 and collagen type I.

11 kDa A. pyogenes cell wall protein that binds collagen type I.

12 MCs made quiescent by attaching to fibrillar collagen type I.

13 t stromal cells that synthesize and organize collagen type I.

14 collagen matrices or on cellular adhesion to collagen type I.

15 r post-translational modification status for collagen type I.

16 e hepatic collagen accumulation dominated by collagen type I.

17 nd are essential for the binding of SPARC to collagen type I.

18 he ability of IGF-1 to increase synthesis of collagen type I.

19 ular matrix molecules that primarily include collagen type I.

20 the sequencing of approximately 1.5-Myr-old collagen type I(4), and suggested the presence of protei

21 A distinctive structural feature of all collagen types is a unique triple-helical structure form

22 We demonstrate that collagen type I, a potent inducer of Rac1-dependent cell

23 measured a significantly increased amount of collagen type I accumulated in the skin of MMP-14(Sf-/-)

24 ia, glomerulosclerosis, and reduced cortical collagen type I accumulation.

25 expression levels while increasing CCN2 and collagen type I activities.

26 Secreted wild-type MMP1 degraded collagen type I after activation, whereas secreted mutMM

27 -fold compared with controls; P < .0001) and collagen type I alpha 1 chain (0.29 +/- 0.17-fold compar

28 osition (Masson's trichrome, hydroxyproline, collagen type I alpha 1 chain, and collagen type I alpha

29 xpression of proteins that promote fibrosis (collagen type I alpha 1 chain, tissue inhibitor of metal

30 yproline, collagen type I alpha 1 chain, and collagen type I alpha 2 chain).

31 The migration of collagen type I alpha chains produced by these fibroblas

32 Hcy-thiolactone modifies lysine residues in collagen type I alpha-1 chain.

33 of Tsc-22 (TGF-beta-stimulated clone 22) and collagen type I alpha-2 (Col1a2) expression in MC throug

34 otif in the 5'-UTR of the mRNAs encoding the collagen type I alpha-subunits (alpha1(I) and alpha2(I))

35 nt protein (GFP) under the regulation of the collagen type I, alpha 1 (coll1a1) promoter and enhancer

36 ntiation as shown by smooth muscle actin and collagen type I, alpha 1 abundance.

37 ta, tissue inhibitor of metalloproteinase 2, collagen type I, alpha 1, and collagen type I, alpha 2)

38 oproteinase 2, collagen type I, alpha 1, and collagen type I, alpha 2) gene expression.

39 (beta-catenin, LEF1) and TGF-beta (Smad2/3, collagen type I, alpha-SMA) signaling, respectively.

40 liver fibrogenesis, as evidenced by reduced collagen type I alpha1 expression and the lack of septum

41 these animals, as demonstrated by decreased collagen type I alpha1 mRNA and receptor activator of NF

42 oth muscle actin positive myofibroblasts and collagen type I alpha1 synthesis.

43 organic portion of the bone, which includes collagen type I alpha1, proteoglycans, and matrix protei

44 enic mice where a 3.6-kb fragment of the rat collagen type-I alpha1 promoter directs HEY2 expression

45 A fragment of the human collagen Type I (alpha1) polypeptide with global Hyp for

46 icant reduction in cardiac expression of pro-collagen type I alpha2 mRNA level, as well as marked red

47 n vivo histone H4 acetylation at the COL1A2 (collagen, type I, alpha2) locus.

48 ent of neointimal proteoglycans, hyaluronan, collagen (types I and III), SMCs, and CD44 (a cell surfa

49 es the number of melanoma cells attaching to collagen (types I and IV) and tissue culture polystyrene

50 regulation of mesenchymal markers, including collagen type I and alpha-smooth muscle actin, and a red

51 ling of ER-resident molecular chaperones for collagen type I and bone metabolism and a crucial role o

52 Both populations of fibroblasts express collagen type I and expand by cell division during tissu

53 oncentrations of insulin neither up-regulate collagen type I and fibronectin deposition nor stimulate

54 n of extracellular matrix components such as collagen type I and fibronectin in normal primary adult

55 both a dose- and time-dependent increase in collagen type I and fibronectin production.

56 ng growth factor-beta, which in turn impacts collagen type I and III deposition, neointimal formation

57 acidic protein, hyalocyte markers, and anti-collagen type I and III was seen.

58 f CIITA III and IV correlates with decreased collagen type I and increased MHC II gene expression.

59 tumors was correlated with higher levels of collagen type I and its organization into fibrils.

60 A strong correlation between Hsp47 and collagen type I and IV expression was seen in NB cells.

61 upport a role for Hsp47 in the regulation of collagen type I and IV production in NB cells and sugges

62 pha-smooth muscle actin and large amounts of collagen type I and matrix metalloproteinase-2, characte

63 s1 strongly suppresses TGF-beta induction of collagen type I and other matrix-related genes and rever

64 rich (SPARC) is a glycoprotein that binds to collagen type I and other proteins in the extracellular

65 over, Sdc3(-/-) MSCs adhered more rapidly to collagen type I and showed a dramatic increase in AKT ph

66 stic hallmarks, and increasingly synthesized collagen type I and tenacin-C.

67 four interactions formed between epitopes of collagen type I and the collagen-binding fragment (gelat

68 asts lost their ability to process fibrillar collagen type I and to activate proMMP-2.

69 has been shown to regulate the expression of collagen type I and transforming growth factor-beta1 in

70 help to explain the observed differences in collagen type I and type II fibrillar architecture and i

71 it low expression (relative to wild type) of collagen type I and type III but show a persistently ele

72 In addition, both collagen type I and type III deposits were evident and c

73 ded, and cultured with autologous serum onto collagen type I and type III membranes in the course of

74 haIII mRNA and their translational proteins, collagen type I and type III, in response to pharmacolog

75 r data demonstrate that corneal cross-linked collagen type I and type IV are resistant to cleavage by

76 s (n=10) and controls (n=10) were tested for collagen types I and III and CTGF expression.

77 blasts that produced ECM proteins, including collagen types I and III and fibronectin.

78 lated ligament fibroblast markers, including collagen types I and III and tenascin-C, fostered statis

79 significantly increased expression of aortic collagen types I and III as well as CTGF, which is likel

80 ygous mutants displayed decreased binding to collagen types I and III but also decreased binding to p

81 Reduced synthesis of collagen types I and III is characteristic of chronologi

82 Collagen types I and III mRNAs were elevated in both fib

83 l fibrosis-related proteins (TGFbeta1, CCN2, collagen types I and III, and FGF2), and higher muscle n

84 content of total and cross-linked collagen, collagen types I and III, MMP-1, MMP-9, TIMP-1, and angi

85 enhanced the production of matrix components collagen types I and III, tenomodulin, and tenogenic tra

86 d secretion of extracellular matrix proteins collagen types I and IV and fibronectin.

87 t the identification of fibronectin (FN) and collagen types I and IV as specific ligands for endosial

88 d that GF and PDLF adhere to vitronectin and collagen types I and IV more avidly than do DF.

89 ectively, through flow cytometry, binding to collagen types I and IV, and Western blot analysis.

90 teins fibronectin, vitronectin, laminin, and collagen types I and IV.

91 erent from that of fibronectin, laminin, and collagen types I and IV.

92 e staining; (3) by the relative synthesis of collagen types I and V, determined by (14)C-proline radi

93 roblasts synthesized a similar proportion of collagen types I and V.

94 fibrosis, synthesis of the major subunits of collagen types I and VI, and the profibrotic factor alph

95 agenolytic activity and impaired invasion of collagens type I and IV.

96 ronectin, laminin, vitronectin, RGD peptide, collagen type I, and collagen type IV) adsorbed to tissu

97 galectin-3, carboxy-terminal telopeptide of collagen type I, and endothelin-1 levels were higher in

98 to hyperproliferation, increased adhesion to collagen type I, and increased apoptosis.

99 oteinase 1, carboxyl-terminal telopeptide of collagen type I, and soluble ST2 were measured at baseli

100 A(2), COX-2, PGE(2) and its receptors (EPs), collagen type-I, and MMPs.

101 by double-labeling with anti-human MMP1 and collagen type I antibodies.

102 eported that naturally occurring peptides of collagen type I are elevated in urine of patients with c

103 Achilles tendon primarily consist of similar collagen type I arrays that can be imaged using SHG micr

104 eted MMP1 was evaluated by FRET and rat tail collagen type I assays.

105 did not observe increased binding of VEGF to collagen type I at acidic pH in the presence or absence

106 sed the collagen content with an increase of collagen type I biosynthesis and reduction of collagen t

107 d increased carboxyl-terminal telopeptide of collagen type I by 4% (95% CI: 1% to 8%; p = 0.02) compa

108 of extracellular matrix proteins, including collagen type I, by activated hepatic stellate cells (HS

109 y 3-hydroxylates proline at a single site in collagen type I chains, whereas P3h2 is responsible for

110 esence of autoantibodies against: (a) native collagen type I (CI) and collagen type III (CIII); (b) C

111 ifferent affinities and binding kinetics for collagen type I (CI) in vitro.

112 -20% of cells bound) to fibronectin (FN) and collagen type I (CI) than did OG1RF (approximately 1% of

113 d seven other isolates) exhibited binding to collagen type I (CI).

114 ratio between the C-terminal telopeptide of collagen type I (CITP) and matrix metalloproteinase-1 (C

115 ed by plating the resultant muscle slurry on collagen type I-coated flasks where the cells adhere at

116 ARPE-19 cells were grown on plastic and on collagen type I-coated membrane inserts in media contain

117 mRNA expressions of bone sialoprotein (BSP), collagen type I (COL-I), osteocalcin (OCN), runt-related

118 nsition coincides with the overproduction of collagen type I (COL1) and other extracellular matrix pr

119 rong induction of alpha-smooth muscle actin, collagen type I (COL1A1), and tissue inhibitor of matrix

120 ng FIB molecules, as well as between FIB and collagen type I (Coll-I) proteins (in vitro and ex vivo)

121 d stimulation of procollagen alphaI mRNA and collagen type I collagen expression were regulated by si

122 We compared expression of HOXA11, collagen type I, collagen type III, MMP2, and MMP9 in US

123 matrix (ECM) proteins, including fibrinogen, collagen type I, collagen type IV, fibronectin, and lami

124 65K protein has markedly reduced avidity for collagen type I compared with LAIR-1 wt.

125 howed increased adherence to fibronectin and collagen type I compared with vitronectin, consistent wi

126 lds most multicellular animals together, and collagen type I constitutes the major fibrillar collagen

127 tworks formed from un-cross-linked fibrin or collagen type I continually changes in response to repea

128 in a rabbit model of PVR and in an in vitro collagen type I contraction assay.

129 aline phosphatase concentrations and urinary collagen type I cross-linked N-telopetide concentrations

130 g biomarkers reflecting excessive myocardial collagen type-I cross-linking and deposition is associat

131 markers associated with excessive myocardial collagen type-I cross-linking or CCL+ (i.e., decreased c

132 evelopment of an in situ-forming hydrogel of collagen type I crosslinked via multi-functional polyeth

133 atase (b-ALP), and terminal C telopeptide of collagen Type I (CTX) were analyzed.

134 prevented tubulogenesis in three-dimensional collagen type I culture in response to hepatocyte growth

135 1-positive regulatory T (T(reg)) cells, and collagen type I deposition by 7 days after inoculation,

136 ckening of the perivascular space (fibrillar collagen type I deposition) and affected almost exclusiv

137 inase-1 ratio) and with excessive myocardial collagen type-I deposition or CD+ (i.e., increased carbo

138 -vaccinated mice revealed markedly decreased collagen type I expression and up to 70% greater uptake

139 alpha1 enhanced collagen type II and reduced collagen type I expression by cultured CPCs.

140 te alpha-smooth muscle actin (alpha-SMA) and collagen type I expression in Ang II-exposed cardiac fib

141 tor cross-talk underlies alpha-SMA-dependent collagen type I expression in cardiac fibroblasts expand

142 we describe a role for the protein TRAM2 in collagen type I expression in hepatic stellate cells (HS

143 ion levels are inversely correlated with the collagen type I expression levels.

144 IGF-1 increased both LARP6 and collagen type I expression via a post-transcriptional an

145 However, collagen type I extracted from both Sc65(-/-) and P3h3(-

146 ationship during human thrombus formation on collagen type I fibers at high shear (1000 s(-1)), we te

147 that ET reduced age-associated elevation of collagen type I fibers.

148 areas between the myofibers adjacent to the collagen type I fibers.

149 UTP nick end labeling [TUNEL] assay), and of collagen type I fibers.

150 o immobilized fibronectin, keratin, laminin, collagen type I, fibrinogen, hyaluronic acid, and hepari

151 TGF-beta2 increased the production of collagen type I, fibronectin, and alpha-SMA.

152 Expression of the EMT markers, collagen type I, fibronectin, and alpha-smooth muscle ac

153 s were GFP expressing and immunopositive for collagen type I, fibronectin, and CD44.

154 dependence of EPC adhesion (to vitronectin-, collagen type I-, fibronectin-, and laminin-coated plate

155 Here we used micropatterned lines of collagen type I/fibronectin on deformable surfaces to st

156 Collagen type I, for instance, forms transparent corneal

157 ocess and increase the synthesis of bFGF and collagen type I from both GFs and PDLFs.

158 The SHG spectral response of collagen type I from bovine Achilles tendon matched that

159 Collagen type I from bovine Achilles tendon was imaged f

160 iffusion coefficients of tracer molecules in collagen type I gels prepared from 0-4.5% w/v solutions

161 infiltration in plain or Matrigel-containing collagen type I gels.

162 ly, neither PGE2 nor LTB4 treatment affected collagen type I gene expression.

163 ntial role in regulating basal expression of collagen type I gene in dermal fibroblasts.

164 interferon (IFN)-gamma-induced repression of collagen type I gene transcription in fibroblasts.

165 eron-gamma (IFN-gamma)-induced repression of collagen type I gene transcription.

166 sforming growth factor beta induction of the collagen type I gene.

167 g embryonic and larval development the three collagen type I genes showed a similar spatio-temporal e

168 On the other hand, RFX5 interacts with both collagen type I genes with a similar binding affinity an

169 interferon gamma-mediated repression of both collagen type I genes.

170 ne phosphatase and N-terminal telopeptide of collagen type I have shown some utility in predicting wh

171 grammetry with CAD/CAM techniques to develop collagen type I hydrogel scaffolds and their respective

172 stresses imparted on cells embedded within a collagen type I hydrogel, and we demonstrate that IF str

173 lture model was established; within a dilute collagen-type I hydrogel, a novel clonal strain of rat c

174 tructions of these ears were fabricated from collagen type I hydrogels.

175 lls, matrix metalloproteinases-2 and -9, and collagen type I, II, and III were positive tested irresp

176 rated specific binding of all three forms to collagen types I, II, and III, thus identifying collagen

177 tes adhesion of blood platelets to fibrillar collagen types I, II, and III, which is essential for no

178 pivotal role in degradation of interstitial collagen types I, II, and III.

179 agged CbpA (HIS-CbpA) was capable of binding collagen types I, II, and IV but not fibronectin.

180 The fibrillar collagen types I, II, and V/XI have recently been shown

181 Collagen types I, II, and VI powders (nonfibrous) did no

182 or 3-hydroxylating multiple proline sites in collagen types I, II, IV, and V.

183 er, compared with other vertebrate fibrillar collagens (types I, II, III, V, and XI), type XXVII coll

184 recombinant version of mature GehD binds to collagens type I, II, and IV adsorbed onto microtiter pl

185 , the majority of which encode the fibrillar collagen types I, III and V, modifying or processing enz

186 ferent layers of the vascular wall including collagen types I, III, and IV, as well as elastin, fibro

187 fibrogenesis; these target molecules include collagen types I, III, and IV, transforming growth facto

188 of binding of anti-rBclA antibodies to human collagen types I, III, and V and found no discernible cr

189 asal membrane (ECM/BM) components, including collagen types I, III, IV, and V and laminin.

190 at the level of the sclera and consisted of collagen types I, III, IV, V, and VI; elastin; and fibro

191 ic protein [GFAP]) and extracellular matrix (collagen types I, III, IV, V, VI; fibronectin; and elast

192 omponents (elastin, fibrillin-1, fibulin-4), collagens (types I, III, and IV), and lysyl oxidase cros

193 ha(2) (alpha(1)I and alpha(2)I) to fibrillar collagen types I-III and showed that each I domain bound

194 Myocardial fibrosis, total collagen, and the collagen type I/III ratio (p < 0.01) were dramatically i

195 precoated with laminin, fibronectin, fibrin, collagen types I/III, or elastin.

196 In conclusion, (1) maximal expression of collagen type I in activated HSCs requires Smad3 in vivo

197 mmunohistochemistry showed faint staining of collagen type I in areas of trabecular meshwork with hig

198 IL-17 directly induced production of collagen type I in hepatic stellate cells by activating

199 decreased adhesion to laminin, gelatin, and collagen type I in normal human diploid fibroblasts and

200 on of active MMP-1 enzyme and degradation of collagen type I in the ECM of cell/tissue systems and TT

201 ediator by which IGF-1 augments synthesis of collagen type I in vascular smooth muscle, which may pla

202 lays an inhibitory role in HSF attachment to collagen type I in vitro through interactions with alpha

203 ECSOD(R213G) and ECSOD proteins bound to collagen type I in vitro, but binding to aorta ex vivo w

204 mary lymphatic tissue fibroblasts to produce collagen type I in vitro; and (3) high levels of immune

205 ata are therefore relevant to the control of collagen type I in vivo both in embryonic development, i

206 ooth muscle actin, phosphorylated Smad3, and collagen type I increased at 48 hours, suggesting that a

207 lular matrix (sulfated glycosaminoglycan and collagen type I), indicating a favorable environment for

208 Altered microarchitecture of collagen type I is a hallmark of wound healing and cance

209 Collagen type I is a structural protein that provides te

210 In tetrapods collagen type I is a trimer mainly composed of two alpha

211 Collagen type I is an AAB heterotrimer assembled from tw

212 Collagen type I is composed of three polypeptide chains

213 When collagen type I is mixed with individual purified, non-g

214 nscriptional control of the genes coding for collagen type I is regulated by a complex interaction be

215 Because collagen type I is the main component of the osteoid, we

216 Collagen type I is the most abundant component of extrac

217 ated with that of beta-dystroglycan, whereas collagen type I levels were elevated in all patients wit

218 of the mice, Cthrc1 was associated with high collagen type I levels; no Cthrc1 or collagen was observ

219 an important role during the proteolysis of collagen type I matrices.

220 antitative immunohistology demonstrated that collagen type I matrix deposition and macrophage and ost

221 ithelial cells were isolated and seeded on a collagen type I matrix with embedded colonic fibroblasts

222 bioartificial arteries were engineered from collagen type I matrix, human vascular smooth muscle cel

223 In a dense collagen type I matrix, there is insufficient space for

224 II signaling on a 2D substrate or in a loose collagen type I matrix.

225 ll as for assessing the relationship between collagen type I metabolism and aqueous outflow.

226 ll as for assessing the relationship between collagen type I metabolism and optic nerve axon loss.

227 fibroblasts (HPTFs), the gene expression of collagen type I, MMP-1 and MMP-3, as well as the protein

228 both bound to three specific sites along the collagen type I molecule, at the N terminus and at 100 a

229 es their translation into the heterotrimeric collagen type I molecule.

230 Collagen type I molecules are a crucial component of the

231 of TGF-beta1, alpha-smooth muscle actin, and collagen type I mRNA and protein levels were determined

232 Consistent with these observations, collagen type I mRNA and protein levels were increased i

233 BAPN treatment increased collagen type I mRNA and protein levels, but genipin red

234 verexpression caused a dramatic reduction in collagen type I mRNA and protein levels.

235 ansforming growth factor beta stimulation of collagen type I mRNA and the alpha2(I) collagen promoter

236 , lefty transduction significantly decreased collagen type I mRNA expression and simultaneously incre

237 connective tissue growth factor that induces collagen type I mRNA.

238 L-1beta significantly decreased the level of collagen type-I mRNA in tendon fibroblasts.

239 Further analysis revealed the presence of collagen type I on the endothelial wall of these vessels

240 nt collagen type-II on type-II scaffolds and collagen type-I on type-I scaffolds.

241 nner but did not attach to the ECM component collagen type I or IV or to the negative control protein

242 vitronectin, fibronectin, or laminin but not collagen type I or IV.

243 n cells were either grown in the presence of collagen type I or serum but not in the presence of fibr

244 . 0.32 microg x ml(-1)), but did not bind to collagen types I or IV.

245 er protease-generated fragments of denatured collagen (Type I) or denatured collagen that contain the

246 on tissue culture plastic, PDL-derived ECMs, collagen Type I, or fibronectin.

247 d with less LV fibrosis (p<0.01) and reduced collagen types I (p<0.05) and III (p<0.05) expression 3

248 tion on the 3D printed material, coated with collagen type I, poly-L-lysine and gelatine, was perform

249 PDL-derived ECMs and collagen Type I-pretreated plates promoted increased cel

250 t despite the reported importance of PDI for collagen type I production, the rate of collagen type I

251 , in transiently transfected SMCs, represses collagen type I promoters (COL1A1 and COL1A2) and activa

252 3-kinase, LY294002, significantly inhibited collagen type I protein and mRNA levels.

253 racellular H(2)O(2), lipid peroxidation, and collagen type I protein in stellate cells co-cultured wi

254 ctin (alpha-sma), intracellular and secreted collagen type I protein, and intra- and extracellular H(

255 of PDLFs at 12 hours and increased bFGF and collagen type I release from GFs and PDLFs at 24, 48, an

256 transient responses of cells seeded in a 3D collagen type I scaffold.

257 en alpha1(I) mRNA level by 60% and decreased collagen type I secreted into the cellular medium by 50%

258 ng/ml tumor necrosis factor-alpha, increased collagen type I secretion (P = 0.03), increased secretio

259 for collagen type I production, the rate of collagen type I secretion appeared normal.

260 Pulse-chase experiments showed that collagen type I secretion was mildly delayed in skin fib

261 ent peptides contains 18 residues of "guest" collagen type I sequence flanked by N and C-terminal (Gl

262 First, we generated dense collagen type I sheets by mechanically compressing colla

263 sent a crystallographic determination of the collagen type I supermolecular structure, where the mole

264 ed by determining hydroxyproline levels, and collagen type I synthesis by ELISA.

265 Viability, proliferation, bFGF, and collagen type I synthesis from both cell types were eval

266 e established that mTOR positively regulates collagen type I synthesis in human fibroblasts.

267 bFGF and collagen type I synthesis was also increased in both cel

268 Collagen type I synthesis was upregulated in ischemic ti

269 sic fibroblast growth factor (bFGF) release, collagen type I synthesis, and wound healing.

270 Here we report a collagen type I targeting protein-based contrast agent (

271 in levels, but genipin reduced the levels of collagen type I, tenascin C, elastin and versican.

272 t to its use is the poor characterization of collagen type I, the most abundant protein in bone and s

273 nclear how VWF recognizes the heterotrimeric collagen type I, the superstructure of which is unknown.

274 tly different from each other for the imaged collagen type I tissue, it is crucial to determine the f

275 s LV collagen cross-linking and the ratio of collagen type I to III, which is associated with increas

276 er, the addition of vitronectin, laminin, or collagen type I to these same ABMs substantially increas

277 ., decreased carboxy-terminal telopeptide of collagen type-I to matrix metalloproteinase-1 ratio) and

278 engineered to overexpress CRT have increased collagen type I transcript and protein.

279 of CCN2 followed by virtual blockade of both collagen type I transcription and its accumulation.

280 -dependent pathway that specifically targets collagen type I transcriptional activation leading to a

281 Using a collagen type I transgenic reporter mouse, we showed tha

282 alpha1(I) propeptide and of disulfide-bonded collagen type I trimer are reduced by 70%.

283 A key self-organizing step, common to all collagen types, is trimerization that selects, binds, an

284 d decreased cell viability and expression of collagen type I, type III, tenomodulin, and phosphorylat

285 LRPs, a model reaction system using purified collagen type I, type IV, and nonglycosylated, commercia

286 periments demonstrate that aegyptin binds to collagen types I-V (K(d) approximately 1 nm) but does no

287 nd assembly of collagenous ECM, specifically collagen types I, VI, and XIV.

288 Increased accumulation of collagen type I was detected in MMP-14(Sf-/-) fibroblast

289 Adhesion to collagen type I was determined with a binding assay.

290 rTGFBIp (50 microg/mL) on cell attachment to collagen type I was determined with the use of fluid-pha

291 hemotactic stimulation by TGF-beta(1)/EGF or collagen type I was insufficient in inducing migration o

292 Transwell coculture system, with or without collagen type I, was used to study the effects of fibros

293 nt reductions in adherence to fibrinogen and collagen type I were observed with deletion of empA and

294 expression and intracellular accumulation of collagen type I, whereas loss of GLT25D2 had no effect o

295 25 microg/mL; P <or= 0.05) HSF attachment to collagen type I, whereas rTGFBIp did not significantly a

296 ha-actin stress fibers and the deposition of collagen type I, which are hallmark features of myofibro

297 These cells are also the primary source of collagen type I, which contributes to decreased chemothe

298 ol1a1(tm1Jae), has been developed to produce collagen type I, which is resistant to degradation by hu

299 oma culture, consisting of a bottom layer of collagen type I with embedded fibroblasts followed succe

300 TIMP)-1, TIMP-2 and C-terminal propeptide of collagen type-I with incident AF were examined after adj