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1 red protons (mainly in the distal tubule and collecting duct).
2 er (NDCBE) in beta-intercalated cells of the collecting duct.
3 he highest expression in the inner medullary collecting duct.
4 d MUC1 in the thick ascending limb, DCT, and collecting duct.
5 ae-like structure on the luminal side of the collecting duct.
6 ecretion, by metering sodium delivery to the collecting duct.
7 ores in principal cells that line the kidney-collecting duct.
8 AQP2 accumulate at the apical surface of the collecting duct.
9 ation by facilitating water transport in the collecting duct.
10 ule, the connecting tubule, and the cortical collecting duct.
11 ibrotic signaling within cells of the kidney collecting duct.
12 lls of the juxtaglomerular apparatus and the collecting duct.
13 I specifically in the principal cells of the collecting duct.
14 protein and regulatory proteins in the renal collecting duct.
15 n-mediated transcriptional regulation in the collecting duct.
16 shed targets of vasopressin signaling in the collecting duct.
17 lial cells, and is localized to the cortical collecting duct.
18 permeability from the proximal tubule to the collecting duct.
19 a(+) channel (ENaC) activity in the cortical collecting duct.
20 amidase and is specifically expressed in the collecting duct.
21 anger expressed in the renal outer medullary collecting duct.
22 ated epithelial cells of the inner medullary collecting duct.
23 ar segments, from the proximal tubule to the collecting duct.
24 ncodes endothelin 1 in the connecting tubule/collecting duct.
25 al fluid resorbed from the loop of Henle and collecting ducts.
26 from principal cells in distal parts of the collecting ducts.
27 ces proliferation in the epithelium of renal collecting ducts.
28 om patients with proteinuria and observed in collecting ducts.
29 late S-shaped body stage and the developing collecting ducts.
30 f cells present in the connecting tubule and collecting ducts.
31 che in proximal and distal renal tubules and collecting ducts.
32 and principal cell fate selection within the collecting ducts.
33 in principal cells of the connecting tubule/collecting ducts.
34 ypertonic medullary interstitium mediated by collecting ducts.
35 f p38MAPK activity in murine inner medullary collecting duct 3 (mIMCD3) cells decreased expression of
37 pha) in renal tubule-derived inner medullary collecting duct 3 cells and show that PI3K-C2alpha resid
39 nvoluted tubules, and the apical membrane of collecting duct A-type intercalated cells, and plays a c
42 ), papillary type 2 kidney cancer (including collecting duct and medullary RCC) (5%), the microphalmi
43 ting ENaC-mediated Na(+) reabsorption in the collecting duct and the development of hypertension.
44 and water balance by principal cells of the collecting duct and the regulation of solute and water b
46 strate plasticity in the fate choice between collecting duct and ureter, and show that an environment
48 embryonic day 13 in the mouse, mainly in the collecting ducts and both the proximal and distal tubule
50 r matrix surrounding the convoluted tubules, collecting ducts and loops of Henle as well as within th
51 that interactions between progenitors of the collecting ducts and nephrons are primarily responsible
52 ater flow across epithelia of isolated mouse collecting ducts and on urine output in mice treated wit
54 which promote low water permeability in the collecting ducts and, hence, free water excretion, remai
56 ifferentiated thick ascending limb of Henle, collecting duct, and stroma; however, it disappeared in
57 PAR2 might control electrolyte transport in collecting ducts, and thereby participate in the regulat
61 luorescent protein (GFP) mice identified the collecting duct as a source of kidney MSC-like cells, wi
62 eter-like 'trunk' from one end of which true collecting duct branches radiate and induce nephron deve
65 d in two regions of the kidney, the cortical collecting duct (CCD) and the thick ascending loop of He
67 distal convoluted tubule (DCT) and cortical collecting duct (CCD) is highlighted by various water an
70 intercalated cells (alphaICs) in the kidney collecting duct (CD) belong to a family of mitochondria
72 es flow-dependent Ca(2+) signaling in murine collecting duct (CD) cells, suggesting that this channel
74 n (AVP)-induced water transport in the renal collecting duct (CD), we hypothesized that if expressed
78 in vitro Homozygous deletion of ILK in renal collecting ducts (CD) of Ilk(fl/fl) ;Pkhd1-Cre mice caus
83 on whole kidneys provides limited insight of collecting duct cell gene expression, because these cell
84 e of fluorescently loaded ECVs into a kidney collecting duct cell line (mCCDC11) and into primary cel
85 Bile acids also regulated ENaC in a cortical collecting duct cell line, mirroring the results in Xeno
86 nases SGK1 and WNK1 were observed in a human collecting duct cell line, while SPAK was unaltered.
88 expression is induced by high-salt levels in collecting duct cells and activates the Slc14a2 gene by
89 imensional polarized cultures of mouse renal collecting duct cells and mice treated with clinically r
90 lia were elongated in proximal tubule cells, collecting duct cells and parietal cells of the remainin
91 nctions of Adam10 in determining the fate of collecting duct cells are more complex than those of a s
92 thium initiated proliferation of mouse renal collecting duct cells but also increased the G2/S ratio,
94 eview documents phosphoproteomic findings in collecting duct cells describing the response to V2R-sel
96 s lacking PC2, NEK8-depleted inner medullary collecting duct cells exhibited a defective response to
99 -type cells, PC1-depleted immortalized renal collecting duct cells had higher levels of integrin-beta
100 g ureteric bud developed kidney agenesis and collecting duct cells had severe cytoskeletal, adhesion
103 nockdown of TRIP13 in murine inner medullary collecting duct cells in the presence of hydrogen peroxi
104 LRRK2 protein is predominantly localized to collecting duct cells in the rat kidney, with much lower
105 teric branching and cell cycle regulation in collecting duct cells in vivo Although in vitro data ind
108 the amount of AQP2 in exosomes released from collecting duct cells is physiologically regulated and e
110 apical membrane of aldosterone-stimulated A6 collecting duct cells revealed that the open probability
111 rom HeLa and mouse principal kidney cortical collecting duct cells significantly decreases cell motil
112 Here, we use deep DNA sequencing in mouse collecting duct cells to ask whether vasopressin signali
113 hormone vasopressin through actions in renal collecting duct cells to regulate the water channel prot
114 n claudin-8, we used cultured mouse cortical collecting duct cells to see how overexpression or silen
115 ic screen in mouse principal kidney cortical collecting duct cells using a GST-SNX27 fusion construct
116 polyomavirus was detected within the graft's collecting duct cells using quantitative polymerase chai
117 ciliary trafficking of polycystins in kidney collecting duct cells without affecting protein levels o
119 apical Na(+) availability in cultured mouse collecting duct cells, enhanced apical Na(+) entry invar
122 n vitro uptake of exosomes by renal cortical collecting duct cells, most studies of human urinary exo
123 ng to a G(alpha) s-coupled receptor (V2R) in collecting duct cells, resulting in increased water perm
139 primarily cultured rat renal inner medullary collecting-duct cells and microarray analysis to identif
143 e post-MI, the remodeling and dysfunction of collecting ducts contribute to the development of chroni
144 2 (AQP2) water channel, expressed in kidney collecting ducts, contributes critically to water homeos
148 revealed cystogenesis in distal tubules and collecting ducts, decreased ciliogenesis in cyst cells,
149 he late connecting tubule and early cortical collecting duct demonstrated that Ba2+-sensitive apical
150 326 preferentially distributes to kidney and collecting duct-derived cysts, displaces miR-17 from tra
153 AT(1A) receptors in epithelial cells of the collecting duct directly modulate aquaporin-2 levels and
154 n deletion of the complex A gene Ift140 from collecting ducts disrupted, but did not completely preve
155 t of inactivation of Sec63 restricted to the collecting duct does not result in overt activation of t
157 ncreased ENaC current in Xenopus oocytes and collecting duct epithelia and enhanced ENaC abundance at
158 report that nephric duct, ureteric bud, and collecting duct epithelia express high levels of grainyh
159 expressed in the kidney proximal tubule and collecting duct epithelia, where it has an important rol
163 ta indicate a direct functional link between collecting duct epithelial barrier characteristics, whic
169 reduction of Notch activity in Adam10 mutant collecting duct epithelium and the similar reduction of
171 phron precursor cells closest to the nascent collecting duct epithelium leads to an active cell invas
172 on, distal cells break into the lumen of the collecting duct epithelium, suggesting that an invasive
177 ed renin formation by principal cells of the collecting ducts forms Ang I from AGT thus increasing An
178 ibit HCO(3) transport in the outer medullary collecting duct from the inner stripe (OMCDi) is not kno
185 s NO production in the renal inner medullary collecting duct (IMCD), the segment with the greatest en
186 ployed proteomic analysis of inner medullary collecting ducts (IMCD) from rats fed with a potassium-f
187 nd activity in the intercalated cells of the collecting duct impaired acid-base regulation by the kid
193 the similar reduction of PC/IC ratios in the collecting ducts in mice deficient for mindbomb E3 ubiqu
194 led loss of aquaporin 2 (AQP2) expression in collecting ducts in patients with elevated bilirubin and
195 Vasopressin controls transport in the renal collecting duct, in part, by regulating transcription.
196 ch in BMP4 promotes differentiation of early collecting ducts into uroplakin-positive, unbranched, ur
197 of Sec63, basal levels of Xbp1s activity in collecting ducts is both necessary and sufficient to mai
198 gase CHIP is highly expressed throughout the collecting duct; is modulated in abundance by vasopressi
199 ured cells or in vivo in rat kidney medullar collecting ducts led to the activation of ERK1/2 through
201 in ZO-1, collagen type IV, as well as UB and collecting duct markers, rearranged during transfection
205 ulture model that uses mouse inner-medullary collecting duct (mIMCD3) cells to generate epithelial sp
209 growth of multiple cell types including the collecting ducts, nephrons, vasculature and interstitium
210 of the Wolffian duct and progenitor for the collecting duct network in the kidney, but they do devel
211 have found that deletion of claudin-8 in the collecting duct of mouse kidney caused hypotension, hypo
213 alpha-Intercalated cells (A-ICs) within the collecting duct of the kidney are critical for acid-base
216 ane staining of beta1 was reduced throughout collecting ducts of AE1-null mouse kidney, where increas
217 GDIalpha is highly expressed in the cortical collecting ducts of mice and rats, and its expression is
219 gans, including the airways of the lung, the collecting ducts of the kidney, and the ducts of the mam
220 hannel present in the principal cells of the collecting ducts of the kidneys that are responsible for
221 ressin [Ca(2+)](i) signaling in split-opened collecting ducts or decreases in aquaporin water channel
222 rvations of papillary stem cell activity and collecting duct plasticity and imply a role for such cel
223 of papillary epithelial cells comprising the collecting duct predominantly but also the loop of Henle
224 llular and paracellular transport, while the collecting duct primarily facilitates transcellular tran
225 ng/trafficking mutant, and length defects in collecting duct primary cilia, the organelle central to
226 olateral membranes in two different cortical collecting duct principal cell lines and in cortical col
227 the fate of genetically labeled adult kidney collecting duct principal cells after Hes1 inactivation
228 enhanced AQP2 apical membrane expression in collecting duct principal cells and reduced urine volume
229 dietary Na(+) intake and aldosterone levels, collecting duct principal cells are exposed to large var
231 ng duct principal cell lines and in cortical collecting duct principal cells in mouse kidney tissue.
232 nockdown of RhoGDIalpha in cultured cortical collecting duct principal cells increased ENaC subunits
238 ar feedback response and/or direct effect on collecting duct principal or intercalated cells may unde
239 onic tubulointerstitial kidney injury, using collecting duct proteostasis defects as a platform for d
240 heterogeneous, low-level transfection of the collecting duct, proximal tubule, distal tubule, interst
241 overexpression enhanced proliferation in the collecting ducts, reduced the size of epithelial duct lu
242 f AT(1) receptors in epithelial cells of the collecting duct regulate water reabsorption, we used Cre
243 onditional inactivation of integrin-beta1 in collecting ducts resulted in a dramatic inhibition of Pk
244 -shaped body formation and in the developing collecting ducts results in proximal tubular and collect
245 Patch-clamp analysis of split-open cortical collecting ducts revealed no difference in baseline acti
246 ordings from principal cells of rat cortical collecting ducts revealed similar inhibitory effects of
250 ntercalated cells (A-ICs) within the nephron collecting duct sense infecting Gram-negative bacteria,
251 tic kidney disease, precystic Ift140-deleted collecting ducts showed normal centrosomal positioning a
252 we generated reporter mouse models to enrich collecting duct specific PC and ICs and reported targete
253 t mice (DE(AC) ), and Edn1 connecting tubule/collecting duct-specific conditional knockout mice (Edn1
255 s of mice: wild-type mice, connecting tubule/collecting duct-specific Dot1l conditional knockout mice
260 from wild-type mice to those of mice with a collecting duct-specific knockout of the transcription f
261 ients developed autoantibodies targeting the collecting duct-specific water channel aquaporin 2, wher
262 , physiologically, showed a kidney- and even collecting-duct-specific expression, including secreted
263 ney-like organoids - complete with nephrons, collecting ducts, stroma, and vasculature - from induced
265 was appropriately increased in the medullary collecting duct, suggesting a localized inhibition in th
266 ng interstitial population into the neonatal collecting duct, suggesting that such intercalation may
267 found that HDAC7 is expressed in the kidney collecting duct, supporting a potential role for this hi
268 the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephro
269 ement of gamma1 laminins for assembly of the collecting duct system basement membrane, in which immob
270 egulatory pathways in the distal nephron and collecting duct system have helped to better our underst
271 lectrolytes and acid-base homeostasis in the collecting duct system of the kidney require an overlapp
272 t TRPV4 is highly expressed along the entire collecting duct system where it appears to function as a
273 strong expression of TRPV4 along the entire collecting duct system with highest levels at the apical
276 pressed in the kidney with dilatation of the collecting ducts, systemic hypertension, and progressive
277 rin 2 (Aqp2)(+) principal cells (PCs) in the collecting ducts that was accompanied by a proportional
278 he proximal tubule and the H+-pump along the collecting duct), the model yields segmental deliveries
279 all cells within the nephron other than the collecting duct through a mesenchyme-to-epithelial trans
280 pressin modulates sodium reabsorption in the collecting duct through adenylyl cyclase-stimulated cycl
281 the symmetry of the system, causing a nearby collecting duct to develop into a uroplakin-positive, br
282 ction-associated barrier components, reduced collecting duct transepithelial resistance, and defectiv
284 probability increased in split-open isolated collecting duct tubules, while ENaC protein levels remai
287 PG synthase type 1 play a role in decreasing collecting duct water permeability and increasing water
289 ), which localizes to principal cells of the collecting duct, we developed mice lacking Dot1l in Aqp2
291 ated into the aquaporin 2-positive medullary collecting duct when microinjected into the kidneys of n
292 r of principal and intercalated cells of the collecting duct where it inhibits K(+) secretion and sti
293 that NaCl loss originated from the cortical collecting duct, where activity of both the epithelial s
294 laterally in alpha-intercalated cells of the collecting duct, where it is functionally coupled with a
295 AQP2) is a water channel found in the kidney collecting duct, where it plays a key role in concentrat
296 decreased slightly in the cortical/medullary collecting duct, whereas BK channel abundance increased
297 e corrective response is orchestrated in the collecting duct, which has several transporters integral
299 Furthermore, pretreatment of split-open collecting ducts with the synthetic agonist peptide sign
300 inantly at the level of aquaporin 2-positive collecting ducts with tubular epithelial and basement me