ライフサイエンスコーパス: common cold

1 iral upper-respiratory-tract infections (the common cold).

2 respiratory tract infections (including the common cold).

3 r harm in these college students who had the common cold.

4 e four seasonal coronaviruses that cause the common cold.

5 ea preparations are widely used to treat the common cold.

6 oviruses (HRVs), is a causative agent of the common cold.

7 Rhinoviruses are a frequent cause of the common cold.

8 experiencing at least 2 of 9 symptoms of the common cold.

9 ruses and monitored for the development of a common cold.

10 ntly reduced the duration of symptoms of the common cold.

11 ng from severe respiratory infections to the common cold.

12 rhinovirus, a major etiological agent of the common cold.

13 SARS-CoV-2 may be no more virulent than the common cold.

14 ID-19 pandemic, as well as influenza and the common cold.

15 luding MERS, SARS viruses, and those causing common cold.

16 myocarditis, acute flaccid myelitis and the common cold.

17 CE Rhinoviruses are one of the causes of the common cold.

18 ytotoxicity by rhinoviruses, which cause the common cold.

19 , B, and C species are defined agents of the common cold.

20 in various diseases, including polio and the common cold.

21 inoviruses are the most common causes of the common cold.

22 described in the 1960s for patients with the common cold.

23 prescribe antibiotics for patients with the common cold.

24 ily previously associated primarily with the common cold.

25 ecretion, and/or sneezing without having the common cold.

26 lation and assessment of signs/symptoms of a common cold.

27 meningitis, encephalitis, hepatitis, and the common cold.

28 alogy to the atmospheric transmission of the common cold.

29 Echinacea is widely used to treat the common cold.

30 on to substantively change the course of the common cold.

31 gical agents of asthma exacerbations and the common cold.

32 f of rhinorrhea and sneezing associated with common colds.

33 rhinovirus (RV) infection and RV-associated common colds.

34 the vitamin E group had a lower incidence of common cold (0.67 vs 0.81 per person-year; RR, 0.83; 95%

35 that caused previous human outbreaks of the common cold; 3) nine SL-CoVs isolated from bats; 4) nine

36 tics were prescribed to 44% of patients with common colds, 46% with URIs, and 75% with bronchitis.

37 nted with a nonbacterial AURI, including the common cold (53.4%), acute bronchitis (31.3%), acute sin

38 stribution modelling, to investigate how two common cold-adapted bird species, willow and rock ptarmi

39 y was also measured to the distantly related common cold alpha-coronavirus, 229E and NL63, and beta-c

40 tudies have demonstrated higher rates of the common cold among persons working in buildings that reci

41 e family are the most frequent cause for the common cold and a major factor in the exacerbation of ch

42 Rhinovirus (RV) is a major cause of common cold and an important trigger of acute episodes o

43 imental inoculation is an important tool for common cold and asthma research.

44 Rhinoviruses cause the common cold and exacerbations of asthma.

45 ousands of years, as annual epidemics of the common cold and influenza disease hit the human populati

46 le of 1981 adults seen by physicians for the common cold and nonspecific upper respiratory tract infe

47 tibiotic, including 51% of patients with the common cold and nonspecific URTIs, 53% with acute sinusi

48 te respiratory tract infections, such as the common cold and pharyngitis.

49 ed insight into pathogenic mechanisms of the common cold and their role in chronic RT illness and has

50 Rhinoviruses are the major cause of common colds and of asthma exacerbations.

51 rk for anticipating the seasonal dynamics of common colds and the associated risks for asthmatics.

52 irus (RV) is responsible for the majority of common colds and triggers exacerbations of asthma and ch

53 culating human coronaviruses (hCoVs) causing common colds and will experience further encounters with

54 iagnosed as having a URI or nasopharyngitis (common cold), and 4.7 million (9% of all prescriptions f

55 coronavirus 229E (CoV-229E) (responsible for common colds), and whether PM (urban, indoor air polluti

56 43, a human beta coronavirus that causes the common cold, and evaluated the top hits against SARS-CoV

57 an coronavirus 229E, a virus that causes the common cold, and find evidence for adaptation in primate

58 erimentally exposed to a virus that causes a common cold, and monitored for 5 d for the development o

59 al improvement after initial symptoms of the common cold, and often associated with facial or dental

60 eCoVs) are etiologic agents for the seasonal common cold, and these eCoVs share extensive sequence ho

61 Human rhinoviruses (HRVs) cause common colds, and the recently discovered HRV-C is incre

62 , the most important etiologic agents of the common cold, are messenger-active single-stranded monoci

63 picornavirus family, is a major cause of the common cold as well as asthma and chronic obstructive pu

64 229E, HCoV-NL63, and human rhinovirus-16 are common cold-associated viruses that exhibit unique featu

65 Our study identifies features shared among common cold-associated viruses, highlighting nasal innat

66 Human Rhinovirus (HRV) is a major cause of common cold, bronchiolitis, and exacerbations of chronic

67 tory viruses are frequent causes of repeated common colds, bronchitis and pneumonia, which often occu

68 Rhinoviruses frequently cause the common cold but have not been considered important cause

69 been widely used as an herbal remedy for the common cold, but efficacy studies have produced conflict

70 s show no association with prevention of the common cold, but exploratory meta-analysis suggests that

71 Human rhinoviruses (RVs) primarily cause the common cold, but infection outcomes vary from subclinica

72 d classes of infectious agents and cause the common cold, cancer, AIDS and other serious health threa

73 n in human subjects with naturally occurring common colds caused by rhinovirus and found a 4.9-fold i

74 those used by endemic coronaviruses or other common cold-causing agents.

75 shared epitopes between SARS-CoV-2 and other common cold-causing coronaviruses.

76 hile binding is abolished by one mutation in common cold-causing HCoV-HKU1.

77 We report the evolution of variants of the common-cold-causing coxsackievirus A21, an EV with tropi

78 and air quality measures are available, but common cold circulation is not; therefore, we generate e

79 eased severity, and reduced incidence of the common cold compared with placebo?

80 reduced incidence and a shorter duration of common colds compared with placebo?

81 Human rhinovirus, the chief cause of the common cold, contains a positive-sense strand of RNA whi

82 an primate (NHP) model of infection with the common cold coronavirus 229E, demonstrating that it mimi

83 rom high avidity pre-existing cross-reactive common cold coronavirus B cell responses, whilst childre

84 icate these T cells could be elicited by the common cold coronavirus OC43.

85 n T cell cross-recognition of SARS-CoV-2 and common cold coronavirus spike proteins.

86 ings provide insights for the development of common cold coronavirus vaccines, demonstrating their po

87 have questioned whether exposure to seasonal common cold coronaviruses (CCCs) could provide tangible

88 bodies against SARS-CoV-2 and seasonal human common cold coronaviruses (CCCs) in hospitalized patient

89 The immune memory to common cold coronaviruses (CCCs) influences SARS-CoV-2 i

90 f SARS-CoV-2 vaccines on T cell responses to common cold coronaviruses (CCCs) remains unknown.

91 to crossrecognition by T cells specific for common cold coronaviruses (CCCs).

92 is whether prior immunity to endemic, human common cold coronaviruses (hCCCoVs) impacts susceptibili

93 de pools derived from the spike protein of 3 common cold coronaviruses (HCoV-229E, HCoV-NL63, and HCo

94 of diverse coronaviruses, including endemic common cold coronaviruses (HCoVs), has been documented,

95 The common cold coronaviruses are a source of ongoing morbid

96 uture pan-coronavirus vaccines.IMPORTANCEThe common cold coronaviruses are a source of ongoing morbid

97 ions of high homology between SARS-CoV-2 and common cold coronaviruses have been highlighted as a lik

98 BACKGROUNDT cell responses to the common cold coronaviruses have not been well characteriz

99 accinated mice were also challenged with the common cold coronaviruses human coronavirus (HCoV)-OC43

100 th comparable affinity to SARS-CoV-2 and the common cold coronaviruses human coronavirus (HCoV)-OC43,

101 ound responses to the spike protein of the 3 common cold coronaviruses in many of the donors.

102 in reduced viral load and pathology for the common cold coronaviruses OC43 and NL63 in mouse models.

103 A decrease in detection of S pyogenes, RSV, common cold coronaviruses, and influenza viruses was obs

104 immune responses to non-human coronaviruses, common cold coronaviruses, and SARS-CoV and Middle East

105 yncytial virus (RSV), 5 influenza viruses, 4 common cold coronaviruses, and SARS-CoV-2, measured by i

106 -CoV-2 as well as two seasonally circulating common cold coronaviruses, OC43 and 229E.

107 Common cold coronaviruses, such as OC43 and HKU1, typica

108 We propose the term "common cold coronaviruses," or ccCoV, to describe the fo

109 inates from previous exposure to circulating common cold coronaviruses.

110 of cross-protection they confer against the common cold coronaviruses.

111 lly approved vaccine to prevent infection by common cold coronaviruses.

112 cross-recognize SARS-CoV-2 and endemic human common cold coronaviruses.

113 homoharringtonine were effective against the common cold coronaviruses.

114 y further be shaped by cross-reactivity with common cold coronaviruses.

115 r any degree of cross-protection against the common cold coronaviruses.

116 ross-recognition by T cells specific for the common cold coronaviruses.

117 ovel coronavirus by T cells specific for the common cold coronaviruses.METHODSWe used the enzyme-link

118 mnestic responses, and cross-immunity to the common-cold coronaviruses.

119 tive T cell recognition between circulating "common cold" coronaviruses and SARS-CoV-2.

120 this reflects T cell memory to circulating 'common cold' coronaviruses.

121 V), which is responsible for the majority of common colds, disrupts airway epithelial barrier functio

122 (RV), a virus responsible for a majority of common colds, disrupts the barrier function of the airwa

123 e adaptive immune responses elicited from a "common cold" eCoV and measured the cross-reactivity agai

124 iruses (RVs) are responsible for millions of common cold episodes and the majority of asthma exacerba

125 ed within 24 h of developing symptoms of the common cold for a randomized, double-blind, placebo-cont

126 through airborne or fecal-oral transmission: common cold, gastroenteritis, bronchiolitis, and acute o

127 Development of a vaccine for the common cold has been thwarted by the fact that there are

128 No consistently effective therapy for the common cold has been well documented, but evidence sugge

129 No effective treatment for common colds has yet been developed.

130 mong persons with HIV, tuberculosis, and the common cold have not been conclusive.

131 axis assays, as do all highly pathogenic and common cold HCoV N proteins.

132 vitro of one of the causative agents of the common cold, HCoV-229E, and the causative agent of the C

133 ," "pharyngitis," "rhinosinusitis," and "the common cold." HIGH-VALUE CARE ADVICE 1: Clinicians shoul

134 lozenges have been used for treatment of the common cold; however, the results remain controversial.

135 Here, we extend these findings to N from the common cold human coronavirus (HCoV)-OC43, which is also

136 Before the pandemic, rhinovirus (RV) and common cold human coronaviruses (HCoVs) were the viruses

137 coronavirus HCoV-OC43 (OC43; an agent of the common cold), human enteric coronavirus (HECoV), equine

138 As the predominant aetiological agent of the common cold, human rhinovirus (HRV) is the leading cause

139 sinfection on RV infection and RV-associated common cold illness in a natural setting.

140 l effect of probiotics for the prevention of common cold illness.

141 2 additional lavages around the time of each common cold illness.

142 (HRV) accounts for a significant portion of common-cold illness, with the peak incidence being in th

143 nt effect of probiotics on the occurrence of common cold illnesses in children, and studies in animal

144 otics may have promise for the prevention of common cold illnesses in children.

145 The total number of common cold illnesses was significantly reduced in the i

146 The incidence of RV infection and of common cold illnesses were evaluated as secondary endpoi

147 on did not reduce RV infection or RV-related common cold illnesses.

148 nificantly reduce RV infection or RV-related common cold illnesses.

149 is associated with a shorter duration of the common cold in healthy people.

150 Second, coronavirus associated with common colds in children may offer some protection, due

151 and other respiratory tract viruses lead to common colds in most infants, whereas a minority develop

152 RSV causes common colds in older children and adults, but can cause

153 n may help determine the clinical outcome of common cold infections, raising the possibility that the

154 The common cold is one of the most frequent human illnesses

155 The common cold is one of the most frequently occurring illn

156 with a range of respiratory illnesses, from common cold-like symptoms to serious lower respiratory t

157 terference can cause a relatively ubiquitous common cold-like virus to diminish during peak activity

158 cell memory to coronaviruses that cause the common cold may underlie at least some of the extensive

159 rus (HRV) infections are associated with the common cold, occasionally with more serious lower respir

160 one car accident [in the control group], two common cold [one patient per group], three gastrointesti

161 ARTI, ranging from 46% of patients with the common cold or nonspecific URTIs to 69% of patients with

162 had any symptoms, which they attributed to a common cold or other non-SARS-CoV-2 infection.

163 nd is a nuisance during mild infections like common colds or the flu.

164 ts of most respiratory disease outbreaks as "common cold" paediatric human pathogens, but reverse zoo

165 Human rhinoviruses (HRVs) were discovered as common cold pathogens over 50 years ago.

166 and predictably drives seasonal variation in common cold prevalence, which results in the "back-to-sc

167 ypes of social ties were less susceptible to common colds, produced less mucus, were more effective i

168 these data provide a mechanism by which "the common cold" promotes diseases due to NTHI, and they add

169 severity with the Sickness Questionnaire and Common Cold Questionnaire.

170 nst the rhinovirus (HRV) responsible for the common cold remains a challenge because there are over 1

171 of action of this substance in treating the common cold remains unknown.

172 tomy, measles, hepatitis A, rheumatic fever, common colds, rubella and chronic sinus infection, in ov

173 ral pathologies ranging in severity from the common cold sore to life-threatening encephalitic infect

174 ral pathologies ranging in severity from the common cold sore to life-threatening encephalitic infect

175 itous human pathogen that is responsible for common cold sores and may also cause life-threatening di

176 The effect of treatment on the severity of common cold symptoms cannot be accurately assessed with

177 the efficacy of any therapy for treatment of common cold symptoms in children less than 6 years of ag

178 developments in the supportive treatment of common cold symptoms in children.

179 The subjective scores for common cold symptoms were recorded daily.

180 es are recognized as the major causes of the common cold syndrome.

181 spiratory tract infections, particularly the common cold, that merits further investigation.

182 Conventional common cold therapies are no longer recommended for use

183 OC43, one of the major etiological agents of common cold, through the induction of IFN-inducible tran

184 n and respiratory illnesses ranging from the common cold to severe wheezing.Objectives: To identify h

185 wide spectrum of disease, ranging from mild common colds to acute respiratory distress syndrome and

186 We jointly fit a common cold transmission model and a model of biological

187 for broad-spectrum antibiotics were for the common cold, unspecified upper respiratory tract infecti

188 oviruses, which are the leading cause of the common cold, utilize intercellular adhesion molecule-1 (

189 ost and viral determinants of disease during common cold versus lethal HCoV infections are poorly und

190 A in purity assessment of a preparation of a common cold virus (human rhinovirus serotype 2, HRV-A2)

191 ooms), administered nasal drops containing a common cold virus (rhinovirus 39), and monitored for 5 d

192 RSV is a common cold virus and the major cause of infantile bronc

193 with a wide range of coronaviruses including common cold virus hCoV-229E, epidemic virus MERS-CoV, an

194 n coronavirus OC43 is a globally circulating common cold virus sustained by recurrent reinfections.

195 y, infection of Ramos cells with rhinovirus (common cold virus) serotypes 14 and 16 resulted in the i

196 Protein mass mapping of the common cold virus, human rhinovirus 14 (HRV14), revealed

197 Most strains of rhinovirus (RV), the common cold virus, replicate better at cool temperatures

198 Most isolates of human rhinovirus, the common cold virus, replicate more robustly at the cool t

199 ced IFN induction, and susceptibility to the common cold virus.

200 er six years, the first structure of a human common cold virus.

201 Such changes were not found following common-cold-virus HCoV-OC43 infection.

202 antigens from SARS-CoV-2, SARS-CoV-1 and the common-cold viruses OC43, HKU1, NL63 and 229E.

203 endemic coronaviruses, RSV, and many other "common cold" viruses, cause significant mortality and mo

204 Although respiratory viruses--the "common cold" viruses--are implicated as a principal caus

205 When common colds were analyzed in a post hoc subgroup analys

206 HRV is the causative agent of the common cold, which in itself is a relatively trivial inf

207 Rhinoviruses (RVs) are the main cause of the common cold worldwide.