ライフサイエンスコーパス: comorbid

1 , geographic distribution, and are often not comorbid.

2 ase cohort had greater 5-year mortality than comorbid (79.2% vs 75.3%; p < 0.001) and matched general

3 the PSENEN mutation carriers presented with comorbid acne inversa (AI), an inflammatory hair follicl

4 [OR] 0.40, CI 0.28-0.57) and increased with comorbid acquired immunodeficiency syndrome (OR 4.52, CI

5 information is available on how primary and comorbid acute myocardial infarction contribute to the m

6 To detect genetic risk variants for comorbid AD and MD and to determine whether polygenic ri

7 sociation study analyzed criterion counts of comorbid AD and MD in African American and European Amer

8 rican participants could be used to estimate comorbid AD and MD.

9 d of all PD cases in the largest studies had comorbid AD.

10 l characteristics of children with AD, ADHD, comorbid AD/ADHD and age-matched healthy controls and to

11 metimes used, especially in individuals with comorbid ADHD.

12 and identified predictors and biomarkers of comorbid alcohol (ethanol)/PTSD-like symptoms in these a

13 lergen sensitization and high frequencies of comorbid allergic diseases are characteristic of severe

14 miniAQLQ scores were worse in patients with comorbid allergy (P = 0.045) and chronic obstructive pul

15 ll survival in groups with varying levels of comorbid Alzheimer's disease pathology according to US N

16 Clinicians should be mindful of this comorbid and co-aggregation pattern as it may influence

17 bsessive-compulsive disorder (OCD) are often comorbid and likely to share genetic risk factors.

18 ctors, diseases secondary to CAD, as well as comorbid and non-CV conditions.

19 r (AUD) and anxiety disorders are frequently comorbid and share mechanisms that could be therapeutic

20 he shared biological mechanisms that lead to comorbid anxiety and cocaine addiction, irrespective of

21 outpatient visits in the previous year, and comorbid anxiety and depression.

22 oman, higher parental education and having a comorbid anxiety disorder were protective factors.

23 ere more likely to be male, younger and less comorbid as defined per Charlson comorbidity index.

24 ders with macrocephaly and/or overgrowth and comorbid ASD.

25 with CRS, both with and without polyps, and comorbid asthma completed the Mini Asthma QOL Questionna

26 strated efficacy in patients with CRSwNP and comorbid asthma previously.

27 Patients with or without comorbid asthma were included.

28 athways for CRSwNP patients with and without comorbid asthma.

29 atus, with highest precision when cases with comorbid attention-deficit/hyperactivity disorder were r

30 ical routines, particularly in patients with comorbid attention-deficit/hyperactivity disorder.

31 comparison models or after the exclusion of comorbid attention-deficit/hyperactivity disorder.

32 intellectual disability (ID) with or without comorbid autism spectrum disorder (ASD) specifically in

33 Exclusion of ADHD cases with comorbid autism spectrum disorder attenuated but did not

34 lethal arrhythmias, often in the setting of comorbid blood pressure derangements.

35 Many subjects with LATE-NC have comorbid brain pathologies, often including amyloid-beta

36 undertook uLMS-PCI in patients with greater comorbid burden and performed more complex procedures co

37 The comorbid cardiometabolic risk of NWCO was also explored.

38 identifying an underlying susceptibility to comorbid cardiovascular disease.

39 actions affecting patients with COVID-19 and comorbid cardiovascular diseases are also becoming a ser

40 ent facility location, travel distance), and comorbid (Charlson-Deyo score) factors and year of diagn

41 hnicity (OR = 3.15; 95% CI = 1.24-8.03), and comorbid chronic lung disease (OR = 3.87; 95% CI = 1.52-

42 growing population of cancer survivors with comorbid, chronic health conditions.

43 1) and used greater resource than the severe comorbid comparator group.

44 Chronic kidney disease is a common comorbid condition among persons living with human immun

45 -36 Symptoms scores worsened with increasing comorbid condition counts.

46 ries and promotes neointima formation in the comorbid condition of hyperlipidemia by potentiating SMC

47 ere older ( P<0.001), had a higher burden of comorbid conditions ( P<0.01), and significantly higher

48 ctive pulmonary disease were the most common comorbid conditions (50% and 25%, respectively).

49 re similar when stratified by obesity, other comorbid conditions (ie, hypertension, hyperlipidemia, a

50 Other neurodevelopmental comorbid conditions (intellectual disabilities, autism s

51 disparities more than susceptibility due to comorbid conditions (low-strength evidence).

52 Differences by sex in cardiovascular comorbid conditions among human immunodeficiency virus (

53 Details were insufficient to adjust for comorbid conditions and ethnicity.

54 in CKD patients, due to their likelihood of comorbid conditions and potential for side effects durin

55 rom treating tinnitus itself to treating its comorbid conditions and secondary effects.

56 Comorbid conditions appear to be common among individual

57 Obstetric and, particularly, medical comorbid conditions are increasing among women who devel

58 risk-reduction strategies for cardiovascular comorbid conditions are warranted for older HIV-infected

59 intolerance, the pathophysiology of HF, and comorbid conditions as they lead to reductions in exerci

60 ma and allergy are not highly represented as comorbid conditions associated with COVID-19.

61 nically evaluated to treat both seizures and comorbid conditions associated with epilepsy.

62 as to quantify procedural risk and burden of comorbid conditions at the time of treatment.

63 Comorbid conditions at time of LTBI testing (e.g., HIV,

64 Comorbid conditions can be pulmonary or extrapulmonary.

65 edication regimens, and careful attention to comorbid conditions can help mitigate these risks and en

66 Residual confounding by comorbid conditions cannot be completely excluded.

67 Identified medical comorbid conditions had high relative risks ranging from

68 Advancing maternal age and preexisting comorbid conditions have contributed to the increased ra

69 Comorbid conditions in ADHD play a key role in symptom p

70 as performed to predict the relative risk of comorbid conditions in BEE developing.

71 effect of NAFLD on development of metabolic comorbid conditions in PWH.

72 Comorbid conditions included overweight/obesity (body ma

73 over the study period by 111%, and obstetric comorbid conditions increased by 30% to 40%.

74 Medical comorbid conditions increased over the study period by 1

75 ransplantation (RT) in the elderly with many comorbid conditions is a matter of concern.

76 Many adults with comorbid conditions lacked critical knowledge about COVI

77 nts with CD have extra-intestinal autoimmune comorbid conditions more frequently than expected.

78 Comorbid conditions of heart failure and diabetes, as we

79 led well-known etiologies, risk factors, and comorbid conditions of HF (including ischemic heart dise

80 the study include an inability to adjust for comorbid conditions or demographics known to impact fibr

81 ars old, 8.3% were indigenous, and 45.1% had comorbid conditions predisposing to severe influenza.

82 Although some of these comorbid conditions share risk factors with IPF, the lik

83 ibility to posttraumatic stress disorder and comorbid conditions such as major depressive disorder an

84 e who did not die were younger and had fewer comorbid conditions than did those who died of causes ot

85 re likely to be white, female, and have more comorbid conditions than those without a fall injury.

86 Bariatric surgery has been shown to improve comorbid conditions that are associated with cardiovascu

87 tanding the root and route of sepsis and its comorbid conditions that complicate treatment outcomes a

88 Medical comorbid conditions were associated with an increasing p

89 ence was scarce, and definitions of MACE and comorbid conditions were heterogeneous.

90 Cardiovascular comorbid conditions were prevalent among older HIV-infec

91 focus from treating tinnitus to managing its comorbid conditions when addressing complaints about hea

92 lure Assessment performance across different comorbid conditions with modification that incorporates

93 were elderly (mean age, 71 years), often had comorbid conditions, and 16% had difficulty with >/=1 ac

94 e, ethnicity, smoking, physical activity and comorbid conditions, and accounting for the competing ri

95 nce with routine vaccinations, management of comorbid conditions, and adherence to treatment regimens

96 tween demographic characteristics, diagnosed comorbid conditions, and documented symptoms with testin

97 ts on NOACs or warfarin were older, had more comorbid conditions, and experienced more severe strokes

98 l fibrillation included demographic factors, comorbid conditions, and most strongly, sepsis-related f

99 Identify demographic factors, comorbid conditions, and symptoms independently associat

100 igate the incidence of BEE, relative risk of comorbid conditions, and treatment patterns using a nati

101 mpared to controls, which was independent of comorbid conditions, but correlated with the severity of

102 -induced liver injury (DILI) frequently have comorbid conditions, but the effects of non-liver comorb

103 Baseline characteristics, presentations, comorbid conditions, endoscopic findings, treatments, an

104 hen controlling for ventilator use, sex, and comorbid conditions, FIB-4 >=2.67 was also associated wi

105 tion of this substrate may vary depending on comorbid conditions, genetics, sex, and other factors.

106 aphic and clinical characteristics including comorbid conditions, health behaviors, medication histor

107 One important phenotype may be related to comorbid conditions, including diabetes mellitus (DM).

108 Comorbid conditions, including heart failure and chronic

109 60% are affected by severe neuropsychiatric comorbid conditions, including impairments in attention,

110 Injury mechanism and severity, comorbid conditions, mental health disorders, and demogr

111 on the basis of age, nursing home residence, comorbid conditions, obesity, respiratory symptoms, resp

112 formats that consider value of care, patient comorbid conditions, patient values and preferences, and

113 most current views on the potential causes, comorbid conditions, proposed subtypes, differential dia

114 After adjustment for sociodemographic and comorbid conditions, rural residence was associated with

115 nts with microbiologic cure, controlling for comorbid conditions, severity of acute illness, appropri

116 nts with microbiologic cure, controlling for comorbid conditions, severity of acute illness, appropri

117 mputerized file (reason for hospitalization, comorbid conditions, suspected or definitive diagnosis o

118 Patient demographic characteristics, comorbid conditions, treatments administered (intravenou

119 tive aging may contribute to cardiometabolic comorbid conditions.

120 n various characteristics and cardiovascular comorbid conditions.

121 carry an increased risk for cardiometabolic comorbid conditions.

122 residence, and a medication-based measure of comorbid conditions.

123 obesity with a minor contribution of chronic comorbid conditions.

124 Most hospitalized children had no comorbid conditions.

125 Hip fracture patients often have comorbid conditions.

126 pes comprising subgraphs of highly connected comorbid conditions.

127 ortion of AIAN cancer patients with multiple comorbid conditions.

128 year, socioeconomic status, age, parity, and comorbid conditions.

129 ion and lower hormone levels, independent of comorbid conditions.

130 f the small bowel, contribute to obesity and comorbid conditions.

131 mes but should be used cautiously with acute comorbid conditions.

132 rgo bariatric surgery based on age, sex, and comorbid conditions.

133 ssible impact of the microbiome on metabolic comorbid conditions.

134 elective operation is elevated secondary to comorbid conditions.

135 xist, including obesity, dietary factors and comorbid conditions.

136 the elderly population and individuals with comorbid conditions.

137 microbiota, immune dysfunction and metabolic comorbid conditions.

138 orporate the effects of aging and associated comorbid conditions; (2) repositories of deeply phenotyp

139 more than 300,000 older adults with multiple comorbid conditions; the estimated proportion of such pa

140 iatal abnormalities in ADHD may be caused by comorbid conduct disorder rather than ODD.

141 Comorbid coronary artery disease (CAD) was present in 24

142 ean [SD] age, 40.1 [10.7] years), the median comorbid criterion count was 6.2 (interquartile range, 2

143 o investigate biopsychological mechanisms of comorbid depression in OCD, we examined effective connec

144 e is more common in women and in people with comorbid depression, anxiety, and other chronic pain con

145 unding variables: childhood trauma exposure, comorbid depression, history of traumatic brain injury,

146 factors can contribute to the occurrence of comorbid depression, such as shared genetic factors, con

147 that PTSD abnormalities may be confounded by comorbid depression.

148 vents included 1 suicide attempt, related to comorbid depression.

149 symptom (PTSS) severity, or were affected by comorbid depression.

150 D may be at especially high risk for certain comorbid developmental conditions (i.e., autism spectrum

151 In contrast, mice with comorbid diabetes (aging, high-fat diet, and streptozoto

152 arly upregulated in the kidneys of mice with comorbid diabetes compared with aged controls, whereas T

153 Upregulation of lung ACE2 activity in comorbid diabetes may contribute to an increased risk of

154 Comorbid diabetes mellitus (DM) increases tuberculosis (

155 hat substance use disorders, as principal or comorbid diagnoses, have the highest absolute and relati

156 g VWI exams, particularly in patients with a comorbid diagnosis of hypertension.

157 te adequate treatment for either disorder, a comorbid diagnosis should be sought.

158 of disease testing, increased prevalence of comorbid disease and reduced access to drugs, resulting

159 ted in large improvements in obesity-related comorbid disease and sustained weight loss over a 5-year

160 e, female sex, diabetes-related ESKD, higher comorbid disease burden, longer durations (>12.0 months)

161 Comorbid disease conditions altering ACE2 expression cou

162 obiological convergence point of these three comorbid disease states.

163 eatment) and patient populations (e.g., age, comorbid disease).

164 hat regions with traditionally high rates of comorbid disease, such as the states located along the G

165 Noninfectious comorbid diseases (NCDs) contribute to morbidity and mor

166 Comorbid diseases were most strongly associated with CRS

167 e disease marked by elevated risk of chronic comorbid diseases, including cardiovascular diseases (CV

168 ulopathy associated with ESKD and from their comorbid diseases, such as hypertension and diabetes.

169 examining the disruption of ACE2 in several comorbid diseases, we offer insight into potential cause

170 tory data, peripheral oxygen saturation, and comorbid diseases, were recorded.

171 epletion, contrast exposure, and preexisting comorbid diseases.

172 ts to reduce RAS induced obesity and related comorbid diseases.

173 in demographics, risk factors for ARDS, and comorbid diseases.

174 maceutical interventions for alcohol use and comorbid disorders may be more effective if designed wit

175 l considerations (eg, genetic influences and comorbid disorders), social and environmental factors ma

176 d with a range of mental and general medical comorbid disorders, and with increased mortality.

177 In addition, narcolepsy and OSA can occur as comorbid disorders.

178 heavier, hepatitis B virus (HCV)+, and more comorbid donors (P < 0.001).

179 Exclusion criteria included substantial comorbid drug or alcohol problems and people who lacked

180 neurologic disorder commonly associated with comorbid emotional alterations.

181 al and promising target for the treatment of comorbid emotional dysfunction associated with epilepsy.

182 tion, avoidance, and sleep disturbance, with comorbid ethanol intake, in a sex-specific fashion that

183 uggest CTE without a thorough exploration of comorbid factors that demonstrate similar clinical pheno

184 ation, biomarker profiling and assessment of comorbid factors to identify subjects most likely to ben

185 ses of variables; demographic, clinical, and comorbid factors, in a two-tiered analysis that included

186 Blacks or Asians, comorbid glaucoma, concurrent or prior glaucoma surgery,

187 gistic, often deleterious interactions among comorbid health conditions, especially under circumstanc

188 aring loss alone or in skin pathologies with comorbid hearing loss.

189 lloid was initiated significantly later with comorbid heart failure and renal failure, with absence o

190 er enrollment and excluding individuals with comorbid heart failure.

191 As the understanding of comorbid HFpEF and DM improves, it is hoped clinicians w

192 reater proportions of smoking (P < .001) and comorbid illness than uninfected comparators.

193 No demographic or comorbid illness was associated with liver injury.

194 It is also critical to screen for and manage comorbid illnesses, such as retinopathy and nephropathy.

195 , but most studies (~85%) did not screen for comorbid impulse control and related disorders.

196 s of anhedonia and anxiety that are so often comorbid in mood disorders.

197 surgery guidelines should include NAFLD as a comorbid indication when determining eligibility.

198 calcium channel blockers, in the absence of comorbid indications.

199 dition, among patients with IgA nephropathy, comorbid inflammatory bowel disease elevates the risk of

200 tis and systemic outcomes, the role of other comorbid inflammatory conditions, selection of study par

201 anipulate a critical therapeutic window post comorbid injury.

202 erapeutically useful for people with OSA and comorbid insomnia.

203 s overall efficacy for ADHD in children with comorbid intellectual disability (ID) or borderline inte

204 of disorders characterized by epilepsy with comorbid intellectual disability.

205 Sixteen eyes of 10 patients with comorbid KC and Fuchs endothelial corneal dystrophy (FEC

206 ; 95% confidence interval [CI] 1.516-2.514), comorbid malignancy (OR 1.943; 95% CI 1.209-3.123), deve

207 ing MDD PRS using MDD GWAS data sets without comorbid MDD-AD cases, significant evidence was observed

208 6 unmedicated individuals with MDD, PTSD, or comorbid MDD/PTSD.

209 In humans, ASD is frequently associated with comorbid medical conditions including sleep disorders, m

210 In humans, ASD is frequently associated with comorbid medical conditions including sleep disorders.

211 This study was conducted to determine any comorbid medical conditions that are associated with sur

212 Demographic and comorbid medical conditions were evaluated in bacteremic

213 tionship between survival and sex, race, and comorbid medical conditions.

214 ents may need to be made for patients with a comorbid medical disorder.

215 of drugs for treatment of both seizures and comorbid memory impairments associated with epilepsy.

216 health care costs and, when associated with comorbid mental health problems, it quadruples the costs

217 the brain reward center may further promote comorbid mood disorders and vulnerability to addiction.

218 prescriptions are dispensed to patients with comorbid mood disorders including major depressive disor

219 SD 1.49) and 14 (88%) of the 16 patients had comorbid mood disorders, anxiety disorders, or both.

220 support a role for glial activation in pain-comorbid NA, identifying in neuroinflammation a potentia

221 is known about the mechanism underlying pain-comorbid NA, previous studies have implicated neuroinfla

222 hich may be more pronounced in patients with comorbid neurodevelopmental disorders.

223 have been implicated in both PTSD and highly comorbid neuropsychiatric conditions, such as anxiety an

224 Comorbid neuropsychiatric disorders such as addiction an

225 were correlated with improvement in tics or comorbid obsessive-compulsive behaviour and to predict c

226 rks associated with improvements in tics and comorbid obsessive-compulsive behaviour, compare the net

227 Demographic data, comorbid ocular conditions associated with RRD, systemic

228 ers (P < .006), fungal cases (P < .001), and comorbid ophthalmic conditions (P < .001).

229 infections, as well as elderly patients with comorbid ophthalmic conditions, as these patients have w

230 o death, including underlying, intermediate (comorbid or antecedent causes), and immediate causes of

231 ative affect is critical in addressing these comorbid outcomes.

232 In 32 patients with comorbid PAA, dupilumab significantly improved PAA contr

233 Dupilumab treatment in patients with comorbid PAR (n = 41) was associated with significant im

234 dupilumab on PAR in severe AD patients with comorbid PAR.

235 the presence of Abeta plaques in vivo, with comorbid pathologies associated with greater neurodegene

236 tween use of nonsurgical clinician visits by comorbid patients prior to surgery and a significantly l

237 ing regimen for allogeneic HSCT for older or comorbid patients with acute myeloid leukaemia or myelod

238 ical need for the growing number of older or comorbid patients with acute myeloid leukaemia or myelod

239 00 person-years [PY]), occurs in older, more comorbid patients, and is associated with greater rates

240 adoption was noted in older, women and more comorbid patients.

241 Finally, in a subset of patients with comorbid PD, treatment with mGluR2 PAM resulted in compl

242 Having a comorbid personality or substance use disorder also incr

243 ations remained after further adjustment for comorbid physical conditions and additional support need

244 th chronic (or recurring) mental illness and comorbid physical health conditions, provide a conceptua

245 with premature mortality and frequently has comorbid physical illnesses suggestive of accelerated bi

246 hanical ventilation were more likely to have comorbid pneumonia and severe sepsis.Conclusions: Noninv

247 isk for adverse TB treatment outcomes, while comorbid, poorly controlled diabetes lessened that risk.

248 icularly before surgery for low tumors or in comorbid populations.

249 ted changes in connectivity in patients with comorbid posttraumatic stress disorder and MDD.

250 ather than a nicotine patch in adults with a comorbid psychiatric condition, initiating varenicline i

251 s with major depression are prone to several comorbid psychiatric conditions, including posttraumatic

252 oup analysis, and excluded participants with comorbid psychiatric diagnoses.

253 history of hazardous alcohol use, and 57% a comorbid psychiatric diagnosis.

254 Anxiety and depression are common, highly comorbid psychiatric diseases that account for a large p

255 self-harm that is partially independent from comorbid psychiatric disorders.

256 rtain personality traits), clinical (such as comorbid psychiatric illness), social and environmental

257 rticipants with cocaine use disorder with no comorbid psychiatric or medical disorders were scanned a

258 Alcohol-dependent individuals with no comorbid psychiatric, medical, or drug abuse disorders w

259 ith SMART-CPT for treatment of veterans with comorbid PTSD and history of TBI reporting cognitive sym

260 uggestive positive interaction observed with comorbid PTSD/TBI in dual-risk factor analyses, with sig

261 ular-first patients were more likely to have comorbid renal failure (36% versus 24%), coronary artery

262 e more often younger, smokers, and with less comorbid risk factors compared with those with lower WBC

263 CNS as a key denominator for obesity and its comorbid sequelae.

264 the development of anxiety, depression, and comorbid substance abuse.

265 Targeting of comorbid substance misuse would have particular effect o

266 higher risk of IPV against women in men when comorbid substance use disorders and personality disorde

267 ion, the authors assessed the association of comorbid substance use disorders with guideline-concorda

268 s in mice and humans to reveal insights into comorbid symptoms of complex diseases.

269 assess the effects of onabotulinumtoxinA on comorbid symptoms of depression and anxiety, respectivel

270 factors differentiated between core ASD and comorbid symptoms-a less appreciated domain of heterogen

271 actors 1 and 2 were associated with distinct comorbid symptoms.

272 modest synergistic excess risk in those with comorbid TBI/PTSD.

273 at OCD is a familial disorder, regardless of comorbid tic disorder status.

274 ves of individuals with OCD with and without comorbid tics, compared with relatives of unaffected ind

275 f this study was to test the hypothesis that comorbid type 2 immune diseases confer protection agains

276 netically predicted expression of GRIK5 with comorbid vascular and eye diseases.

277 a, with stronger associations for LCADs with comorbid wheeze and rhinitis.

278 LA pathway when anxiety and chronic pain are comorbid, which involves the activity of beta-adrenergic

279 PTSD, in turn, is highly comorbid with a plethora of inflammatory disorders and h

280 a disorder of brain-gut-communication highly comorbid with anxiety and depression.

281 m in several rare monogenic syndromes highly comorbid with autism - fragile X and tuberous sclerosis

282 isorders, particularly depression, are often comorbid with both pain disorders and opioid abuse.

283 ism for the attention and memory impairments comorbid with chronic pain.

284 of late-life depression, which is frequently comorbid with cognitive impairment.

285 ed in children with autism spectrum disorder comorbid with intellectual disability, distinctive facia

286 Posttraumatic stress disorder is often comorbid with MDD, and symptoms of both disorders can be

287 Conditions recognised to be comorbid with migraine include asthma, anxiety, depressi

288 ait associated with eating disorders that is comorbid with mood and substance use disorders.

289 Cardiovascular dysfunction is highly comorbid with mood disorders, such as anxiety and depres

290 he mPFC-specific cognitive deficits that are comorbid with neuropathic pain.SIGNIFICANCE STATEMENT Th

291 e.SIGNIFICANCE STATEMENT Aggression is often comorbid with neuropsychiatric diseases, including drug

292 anxiety symptoms, which are also frequently comorbid with other mental disorders, such as major depr

293 is a widespread public health concern often comorbid with other psychiatric disorders.

294 irror movements phenotypes, a phenotype also comorbid with PD.

295 ed emotional states and eating disorders are comorbid with psychiatric symptoms and altered emotional

296 pproaches for the management of chronic pain comorbid with sleep disturbances and for the management

297 Problem gambling is also highly comorbid with substance use disorder, and many commercia

298 bsessive compulsive disorder (OCD) are often comorbid with the overlap based on compulsive behaviors.

299 ger-duration HF patients were older and more comorbid with worse symptoms.

300 Mood disorders and constipation are often comorbid, yet their shared etiologies have rarely been e