ライフサイエンスコーパス: compensated

1 cy dependent signal delays are evaluated and compensated.

2 of the medium and sensor signal drift can be compensated.

3 deficiency on monocyte-derived DCs was fully compensated.

4 ereas 5.4% had cirrhosis but were clinically compensated.

5 ation of Atp6v1b1 were reported to exhibit a compensated acidosis and normal hearing.

6 encompassing the whole spectrum of disease (compensated, acutely decompensated without ACLF, and ACL

7 Patients with compensated advanced chronic liver disease (cACLD) can s

8 Because the detection of compensated advanced chronic liver disease (cACLD) is ve

9 if they fulfilled the following criteria: 1) compensated advanced chronic liver disease (LSM >10 kPa)

10 f they fulfilled the following criteria: (1) compensated advanced chronic liver disease (LSM >10 kPa)

11 proving resource utilization for HIV-related compensated advanced chronic liver disease.

12 improving resource utilization for PLWH with compensated advanced chronic liver disease.

13 of hepatic decompensation: nonadvanced CLD, compensated advanced CLD (CACLD), and decompensated adva

14 ohort study, including patients with HCV and compensated advanced fibrosis that achieved SVR after di

15 ity (VD) were calculated using a reflectance-compensated algorithm.

16 idity minimizes the risk that phenotypes are compensated and that secondary, non-specific defects acc

17 of Sox6(-/-) red blood cells, resulting in a compensated anemia.

18 t that changes in ionic pathway densities in compensated aortic banding rats maintain Ca(2+) function

19 n, highlighting the need for the "aberration compensated" aspect of AC-LSCM.

20 this buoyant refractory arc mantle is likely compensated at depth by denser, likely garnet-rich, lith

21 ncluded that hepatologists at LT centers are compensated at much higher rates per encounter than in o

22 ct of segmental aneuploidy can be moderately compensated at the mRNA level - aneuploid gene expressio

23 the dose effect of aneuploidy can be further compensated at the translational level.

24 d that Z-linked gene expression is partially compensated between sexes in chickens.

25 These effects are rapidly compensated both in culture and in vivo by lipidome-wide

26 phages created alternate, BRD4-less SEs that compensated BRD4 loss.

27 chiasmatic nucleus (SCN) neurons, and may be compensated by a change in Rbfox2 expression.

28 rarefaction inside the plasma center can be compensated by a gas stream application.

29 with an ISM, the negative potential drift is compensated by a positive potential drift related to the

30 sity since mortality due to predation can be compensated by a reduction in disease induced mortality.

31 A significant reduction of GLS could be compensated by a small increase of GCS or wall thickness

32 This deficiency is partially compensated by a unique pattern of microglial migration

33 e that the surface is positively charged and compensated by an attendant negative space-charge zone.

34 enthalpies of adsorption that are partially compensated by an increase in the solvent reorganization

35 versus FGR mean, -21.5% [SD, 1.16]; P<0.001) compensated by an increased circumferential strain and w

36 (B) on the U atoms, which are only partially compensated by antiparallel moments of 1.53(14)-3.26(5)

37 s that the free energy barrier, which can be compensated by applied overpotential, is reduced from 1.

38 aging than the virus infection and could be compensated by applying a 5x higher dose of DEET.

39 rising greenhouse-gas concentrations can be compensated by artificially reducing the amount of sunli

40 rostatic penalty for this close proximity is compensated by attractive interactions provided by the s

41 nner and more abundant vessels, which can be compensated by augmenting the production of Delta ligand

42 emia with reticulocytosis that was partially compensated by avid extramedullary erythropoiesis at all

43 ff-target" effects of 5-ITu can be partially compensated by changes in expression program or accumula

44 limited efficacy of antidepressants might be compensated by combining therapies with targeted treatme

45 in the edge energy of scalloped membranes is compensated by concomitant decrease in the deformation e

46 nt for non-homologous end-joining and is not compensated by DNA ligases 3 or 4.

47 IL-3) for growth, but this dependence can be compensated by ectopic EGFR overexpression, enabling sel

48 her enthalpy of binding, which was more than compensated by entropic costs.

49 rties (e.g. increasing stem sizes) are often compensated by equal magnitude decreases caused by other

50 lising effects of growth can be specifically compensated by feedback mechanism that senses average ca

51 ype of the DeltacobB mutant can be partially compensated by further increase of intracellular TopA le

52 Kupffer cell loss was compensated by gain of adjacent monocyte-derived macroph

53 Cell death was compensated by hepatocyte proliferation and alanine amin

54 t the structural orders with low entropy are compensated by high formation energies due to the pressu

55 hate shunt, which consumes ATP, which can be compensated by higher rates of cyclic electron flow.

56 of these N-cyclopropylanilines can be amply compensated by incorporation of a radical-stabilizing ph

57 The functional isolation was compensated by increased feedback excitation within CA1,

58 c profiles, where depletion of many SFPs was compensated by increased investment in others.

59 ated with mitochondrial uncoupling, were not compensated by increased lactic fermentation.

60 ASCT2 deficiency was compensated by increased levels of sodium neutral amino

61 Reduced EGFR levels can be compensated by increases in HER3; thus, assaying EGFR an

62 ation near an exceptional point is precisely compensated by increasing laser noise.

63 The BP cluster was compensated by interactions involving unpaired cytosines

64 a reduced inward rectification which was not compensated by intracellular spermidine.

65 , the forces (and tensions) can be partially compensated by irreversible interpillar adhesion that re

66 Yet the inefficiency of the ON cell is compensated by its presynaptic arrays providing a higher

67 f perceptual processing, (c) can possibly be compensated by later attentional processes, (d) thus lea

68 The impact of these drawbacks can be partly compensated by manual work that becomes inefficient when

69 mic response to ocean melting) was partially compensated by mass gains over ice sheet interiors (incr

70 reby decreased decomposition of litter C was compensated by more extensive loss of mineral-associated

71 a sub-optimal form (GUG or UUG) tends to be compensated by mutations in the Shine-Dalgarno sequence

72 e amount of extracted Na(+), which is mainly compensated by Na(+)/H(+) exchange.

73 essential and unique function that cannot be compensated by other HDAC complexes.

74 ial microcompartment assembly that cannot be compensated by other shell proteins.

75 , such as whether damage to one route can be compensated by over-reliance on the other.

76 ions from AICAR-fed cells, this effect being compensated by overexpression of KAP123 for 15 of them.

77 ade of glycolysis upon Gpi1 inactivation was compensated by pentose phosphate pathway flux and increa

78 es charge in-neutrality in the GONR which is compensated by releasing *OH functional groups.

79 ergy dissipated by the vibrations is usually compensated by replenishment from external energy source

80 n can cause dNTP imbalances, which cannot be compensated by RNR or other enzymatic activities.

81 Defects in aPBP-dependent wall synthesis are compensated by sigma(I)-dependent upregulation of an Mre

82 trengthening of the strongest storms will be compensated by storm tracks moving offshore at the latit

83 icts bulk secretion, occurs apically, and is compensated by subapical endocytosis, has been challenge

84 intrinsic excitability in UBCs was partially compensated by suppression of the magnitude and duration

85 The new phase contains excess copper, charge compensated by systematic hydroxyl groups, which leads t

86 ficient PTI-mediated resistance is partially compensated by the activation of specific cell-wall-trig

87 IFN-dependent Treg cell loss that is rapidly compensated by the conversion and expansion of Vbeta5(+)

88 ased delivery in these tumors, an effect not compensated by the improved vessel quality.

89 obal H3 occupancy on the chromatin, which is compensated by the increased incorporation of H3.3.

90 d to maintain the genome order, which may be compensated by the internal nuclear viscoelastic propert

91 ative functional diversity in cities are not compensated by the presence of exotic species but are le

92 ion intrinsically featured by lanthanides is compensated by the semiconductor moiety, which harvests

93 h the decay in genetically labeled PCs being compensated by unlabeled PCs, supporting homeostatic pop

94 In Dictyostelium discoideum, loss of SCAR is compensated by WASP moving to the leading edge to genera

95 Enhanced m6A RNA methylation results in compensated cardiac hypertrophy, whereas diminished m6A

96 Reflectance-compensated CD and VD parameters for both NFLP and SVC c

97 d n-type doped, respectively, whereas dopant-compensated CH3NH3PbBr2.94Cl0.06 alloy has over tenfold

98 were at least 20 years of age diagnosed with compensated CHB.

99 Cirrhosis was compensated (Child-Pugh A), without past history of comp

100 hepatic decompensation (13%) than women with compensated cirrhosis (1.2%) (P < .001).

101 primary therapeutic target in patients with compensated cirrhosis (CC).

102 us (HCV) infection without cirrhosis or with compensated cirrhosis (Child-Pugh A) who have: * genotyp

103 l) over time in percentages of patients with compensated cirrhosis (decreases in percentages of patie

104 nts with NASH with bridging fibrosis (F3) or compensated cirrhosis (F4) enrolled in two phase 2b, pla

105 healthy controls (n = 24) and patients with compensated cirrhosis (n = 11).

106 We identified pregnant women with compensated cirrhosis (n = 2022) using validated case de

107 An inception cohort of 202 patients with compensated cirrhosis (no ascites, gastrointestinal blee

108 ction with prior treatment experience and/or compensated cirrhosis achieved high SVR12 rates followin

109 SVR12 rates were 96.4% (297/308) with compensated cirrhosis and 97.5% (2010/2061) without cirr

110 , open-label study enrolled 23 subjects with compensated cirrhosis and PH (hepatic vein pressure grad

111 for 28 days decreased HVPG in patients with compensated cirrhosis and severe PH; an effect upon port

112 ning and surveillance of EV in patients with compensated cirrhosis and to study the effects of an SVR

113 patients in the ANRS-CO12 CirVir cohort with compensated cirrhosis associated with hepatitis B virus

114 ed treatment-naive patients with and without compensated cirrhosis at 15 sites in Canada.

115 comes of individuals aged 50 years with well-compensated cirrhosis entering surveillance.

116 ctive cohort study of patients with incident compensated cirrhosis in the Veterans Health Administrat

117 retrospective cohort study of patients with compensated cirrhosis in the Veterans Health Administrat

118 ive study of patients with HCV infection and compensated cirrhosis included in the CirVir cohort who

119 t-line therapy to patients with HCC and well-compensated cirrhosis instead of primary LT because it m

120 Patients with compensated cirrhosis were randomly assigned to groups t

121 naive or treatment-experienced patients with compensated cirrhosis were treated with G/P for 12 or 16

122 cult cirrhosis (OcC), defined as preclinical compensated cirrhosis without any clinical findings, on

123 ut cirrhosis) or 12 weeks (for patients with compensated cirrhosis).

124 ent in 40 healthy subjects, 39 patients with compensated cirrhosis, 342 with AD (no ACLF) and 180 wit

125 Results In patients with compensated cirrhosis, 40% (129 of 326) experienced deco

126 ction with prior treatment experience and/or compensated cirrhosis, a patient population with limited

127 having cirrhosis, (3) patients with CLD and compensated cirrhosis, and finally, (4) patients with CL

128 notype 1 or 4 HCV infection, with or without compensated cirrhosis, and with an estimated glomerular

129 Serum KP activity was normal in compensated cirrhosis, increased in AD and further incre

130 d May 4, 2016, we enrolled 146 patients with compensated cirrhosis, of whom 48 (33%) had genotype 1a

131 ontrolled pilot study enrolled patients with compensated cirrhosis, portal hypertension (hepatic veno

132 CV-infected population, including those with compensated cirrhosis, previous treatment with an interf

133 lity among a diverse cohort of patients with compensated cirrhosis, using both definitions.

134 xperienced, either without cirrhosis or with compensated cirrhosis.

135 nt in >90% of patients, including those with compensated cirrhosis.

136 primary therapeutic target in patients with compensated cirrhosis.

137 not pibrentasvir exposure, in patients with compensated cirrhosis.

138 whether emricasan lowers PH in patients with compensated cirrhosis.

139 have focused the discussion on patients with compensated cirrhosis.

140 -6 (HCV RNA >/=10 000 IU/mL) with or without compensated cirrhosis.

141 HCV genotype 1, 2, 4, 5, or 6 infection and compensated cirrhosis.

142 s with hepatitis C virus (HCV) infection and compensated cirrhosis.

143 itis C virus infection, including those with compensated cirrhosis.

144 05 (95%) had subtype 3a HCV and 39 (35%) had compensated cirrhosis.

145 ve-treatment groups, 46% of the patients had compensated cirrhosis.

146 HCV genotype 1, 2, 4, 5, or 6 infection and compensated cirrhosis.

147 s with hepatitis C virus (HCV) infection and compensated cirrhosis.

148 and HIV-1 coinfection, including those with compensated cirrhosis.

149 ction, 69% were treatment naive, and 15% had compensated cirrhosis.

150 titis B patients, particularly in those with compensated cirrhosis; older age (especially >/=50 years

151 From observational studies among compensated cirrhotic hepatitis C patients treated with

152 images, which allows image distortions to be compensated computationally and an accurate hyperspectra

153 rimposed on a previously acquired and motion-compensated CT scan.

154 However, for patients with compensated disease, data are limited regarding associat

155 raphy/mass spectrometry (LC/MS) showing that compensated FAF intensities correlate linearly with A2E

156 Here, the SOT switching of a nearly compensated ferrimagnet Gd(x) (FeCo)(1-) (x) by the topo

157 Recently, it was demonstrated that compensated ferrimagnetic half metals can be realized in

158 he topological surface states and the nearly compensated ferrimagnets provides a promising route for

159 by a low adherence to a healthy diet can be compensated for by a normal weight.

160 usly, the decrease in r-protein abundance is compensated for by a reduced dilution of pre-existing ri

161 estabilizing effects of these mutations were compensated for by a subset of the affinity mutations th

162 This was partially compensated for by additional interactions involving cer

163 ity of a higher body mass index (BMI) can be compensated for by adherence to a healthy diet and wheth

164 Although its loss is compensated for by alternative signaling activation mech

165 at the absence of oriented cell divisions is compensated for by an increased contribution of cell rea

166 vely, a decrease in neuronal matter could be compensated for by an upregulation of GABAA receptors.

167 and higher blood pressure, which seem to be compensated for by augmentation of atrial pump function.

168 uced by the mutations in the TLR5 epitope is compensated for by extensive interactions between the ou

169 s in RNA/R domain interactions may have been compensated for by increased intersubunit beta-strand in

170 that metabolic substrate abnormalities were compensated for by increased mitochondrial mass.

171 lymphoid-primed MPP4s, which appeared to be compensated for by increased MPP4 proliferation.

172 promoting activity of myosins, and cannot be compensated for by increasing actin nucleation.

173 responses about the present stimulus can be compensated for by large numbers of neurons.

174 in the aak6 root apex, but this is partially compensated for by longer mature root cells.

175 lost microtubule-actomyosin interactions are compensated for by microtubule-microenvironment interact

176 The loss of Appb might then be compensated for by other app family members to maintain

177 ciency was only apparent for T(conv) and was compensated for by peripheral reconstitution for T(reg)

178 Increased parasitoid activity was not compensated for by reduced life span, indicating that in

179 of a layered material with the charge being compensated for by reversible reduction and oxidation of

180 n megakaryopoiesis, which cannot be entirely compensated for by RUNX1B overexpression.

181 ere is an entropic cost for assembly that is compensated for by the energetic gain of burying hydroph

182 ssociated with an energetic penalty that was compensated for by the favorable electrostatic interacti

183 in PSII-deficient mutant cells can be partly compensated for by the indirect (PSII-independent) H(2)

184 type had reduced chitosan content, which was compensated for by the production of lipids and other no

185 phosphate uptake only slightly, most likely compensated for by the related SLC20A1 transporter, but

186 he absence of de novo dNTP production can be compensated for by the salvage pathway is unknown.

187 pn13 function at proteasomes cannot be fully compensated for by the two other dedicated substrate rec

188 es was markedly reduced but this was largely compensated for by using two or more antibodies in combi

189 In vitro, L74I compensated for defective replication of M184V mutated v

190 In vitro, L74I compensated for defective replication of M184V-mutated v

191 ons specifically at delta frequencies (2 Hz) compensated for deficits in temporal control of action c

192 rturbations altering long-term stability are compensated for even at the cost of higher energy expend

193 d that local variability in structure may be compensated for globally in a homeostatic manner.

194 t between age groups; however, older animals compensated for impaired beacon discrimination through g

195 nd/or changes in biomass allocation may have compensated for increasing evaporative demand, leaving r

196 levels via exogenous, cloned-gene expression compensated for inefficient B protein binding, as did su

197 , greater recruitment of low-elevation seeds compensated for longer dispersal distances to treeline,

198 ally elevated, suggesting that another organ compensated for loss-of-function in the liver.

199 function ability, suggesting that bilinguals compensated for lower levels of cognitive control by rec

200 n increase in replication origin firing that compensated for reduced fork progression.

201 The increased SWS compensated for reduced SWR density so there was no redu

202 We found that the fungus: compensated for resource loss in the 'crash' treatment b

203 In contrast, larger populations compensated for response sparsity, enabling decoding wit

204 iograms obtained from each scan pattern were compensated for signal loss and averaged.

205 Free-living men and women partially compensated for snack energy by decreasing energy intake

206 phosphorylation or Stat3 lysine methylation compensated for the absence of DSCR6 function.

207 Our results not only show that participants compensated for the avatar's manipulated arm movement wh

208 apacity per volume of adipose tissue exactly compensated for the decrease in fat mass during weight l

209 The guppy population compensated for the decreased survival by a density-depe

210 Greater levels of cooperation among larvae compensated for the fitness costs caused by parental abs

211 arental absence, whereas parental care fully compensated for the fitness costs of sibling rivalry.

212 nce that the Na(+)/Cl(-) cotransporter (NCC) compensated for the inactivation of NDCBE.

213 ause the reduction in vitreous chamber depth compensated for the increase in corneal curvature.

214 s in which increased chymosin concentrations compensated for the inhibition, demonstrated that other

215 Importantly, this increased respiration compensated for the lower rates of root exudation in dro

216 sylation efficiency, and Cys, in particular, compensated for the negative effect of Arg at the i-2 po

217 on, and the overexpression of each partially compensated for the other's loss.

218 ific induction of ComM and allolytic factors compensated for the virulence loss in the DeltadprA muta

219 ution of the photoperiodic reaction norm has compensated for this mismatch in Colias eurytheme.

220 We demonstrate that bilaterians compensated for this reduced structural complexity in mt

221 ix effects varied from -67 to +319% and were compensated for using standard addition.

222 This effect was largely compensated for vitamin D by the fact that this vitamin

223 osed as a 'reward deficient' state, which is compensated for with substance use.

224 These effects must be compensated for, if they cannot be removed or reduced by

225 icating that in blood EPT1 inactivity may be compensated for, in part, via alternate biochemical path

226 with ORA gives higher values than thickness compensated GAT.

227 naprevir plus daclatasvir is appropriate for compensated genotype 1b HCV if baseline NS5A mutations a

228 coregistered in 3 dimensions, creating a GPM-compensated (GPMC) image series.

229 Using this method, we compensated group velocity dispersion in the 0.2-0.3 THz

230 he population modeled was restricted to well-compensated HCV(+) cirrhotics listed for liver transplan

231 be the most cost-effective strategy for well-compensated HCV-infected cirrhotics listed for liver tra

232 mia requiring lifelong transfusions to fully compensated hemolysis.

233 rk demonstrates the possibility of employing compensated Heusler alloys for fast, energy-efficient sp

234 ibility weighted imaging (SWI) is a velocity compensated, high-resolution three-dimensional (3D) spoi

235 intrinsic 7.35 degrees angular gap could be compensated homogeneously through phase transformation o

236 Adult clinically compensated HVC patients were consecutively recruited be

237 ts (odds ratio, 1.74; 95% CI, 1.62-1.88) and compensated hypercapnia (odds ratio, 1.18; 95% CI, 1.10-

238 n dioxide levels (normocapnia and normal pH, compensated hypercapnia [normal pH with elevated carbon

239 Patients with compensated hypercapnia and hypercapnic acidosis had hig

240 spective study aimed to assess the impact of compensated hypercapnia and hypercapnic acidosis in pati

241 iated with increased hospital mortality than compensated hypercapnia or normocapnia.

242 atients (normocapnia and normal pH, 110,104; compensated hypercapnia, 20,463; and hypercapnic acidosi

243 ) and Na(+) regulation from the formation of compensated hypertrophy (CH) until signs of heart failur

244 During compensated hypertrophy in vivo fractional shortening (F

245 Compensated hypertrophy is accompanied by an increase in

246 SERCA function remains constant during compensated hypertrophy then decreases in HF, when there

247 SR Ca(2+) content increases during compensated hypertrophy then decreases in HF.

248 ual colour centre optical transitions can be compensated in situ by integrated tuning over 50 gigaher

249 However, these negative outcomes are compensated in the long term by the beneficial influence

250 ix-and-read, free-solution assay (FSA) and a compensated interferometer (CI) can provide a novel alte

251 with high affinity DNA aptamer probes and a compensated interferometric reader (CIR), represents a p

252 Corneal-compensated intraocular pressure (IOPcc) was measured wi

253 Corneal-compensated intraocular pressure was associated most sig

254 r (ORA) (Reichert, Inc., Depew, NY), corneal-compensated IOP (IOP(cc)), and the ICare Rebound Tonomet

255 rrelated intraocular pressure (IOPg), cornea-compensated IOP (IOPcc) using the ORA, and central graft

256 GAT was significantly lower than corneal-compensated IOP in OEs (18.1 +/- 4.9 vs 19.8 +/- 4.8 mm

257 eresis, Goldmann-correlated IOP, and corneal-compensated IOP.

258 nd early expression of a low-avidity epitope compensated its weak intrinsic antigenicity, resulting i

259 We develop aberration-compensated laser scanning confocal microscopy (AC-LSCM)

260 ree UK hospitals and recruited patients with compensated liver cirrhosis and MELD scores of 11.0-15.5

261 e 1, 2, 3, 4, 5, or 6 infection and also had compensated liver disease (with or without cirrhosis) wi

262 Patients with compensated liver disease caused by PSC were randomized

263 Patients with chronic HDV infection and compensated liver disease who were aged 18 years or olde

264 with chronic HCV genotype 1-6 infections and compensated liver disease, including patients with chron

265 /P was safe and efficacious in patients with compensated liver disease, including those with CKD 4/5.

266 ents with HCV genotype 5 or 6 infection with compensated liver disease.

267 adiological evidence of liver cirrhosis, and compensated liver function.

268 latile organic compound (VOC) concentrations compensated low oxidant concentrations indoors to result

269 Vertical strabismus was compensated mainly by significant contractility of the l

270 n of coordinated gene regulation: the dosage-compensated male X chromosome.

271 ach providing respiratory and cardiac motion-compensated MR and PET images in less than 5 min.

272 id registration algorithm and used in motion-compensated MR and PET reconstructions to improve image

273 s of several pockets originating from fairly compensated multi-band electronic structure, in full acc

274 ormal hearts (n=5) and between patients with compensated (n=6) versus decompensated (n=6) CPMR.

275 lost-of-fitness effect of one paralog can be compensated only in a subset of lines.

276 Among the full cohort with compensated or decompensated cirrhosis, 61% (504 of 830)

277 ery and stratified the study population into compensated or decompensated CPMR.

278 copic interactions establishing magnetically compensated order and the macroscopic manifestations of

279 Since severe fibrosis in compensated patients is the main predictor of long-term

280 elatively small sample size and stable, well-compensated population.

281 The arterial blood gas test showed partially compensated pulmonary alkalosis (pH, 7.43; normal range,

282 s were then used to perform the final motion-compensated reconstruction.

283 Reflectance-compensated retinal vessel densities were calculated on

284 gnetic switching can be realized in a nearly compensated sample with strong perpendicular anisotropy

285 s a correlated nearly-complete electron-hole-compensated semimetal.

286 rs, and median age of first transactional or compensated sex was 22 years (IQR 19-28).

287 Reflectance-compensated SVC VD measurement by PR-OCTA detected glauc

288 uch as pollinators or seed dispersers may be compensated through increased interactions with remainin

289 a negligible loss of active sites which was compensated through the effective generation of active s

290 Women compensated to a smaller extent than men.

291 alopathy), which defines the transition from compensated to decompensated stage.

292 ique in this role because no other organisms compensated to maintain bait removal rate in their absen

293 is, and CC OCTA images from drusen eyes were compensated using a previously published strategy.

294 fect of E2F7/8 inactivation can be partially compensated via E2F1-dependent apoptosis.

295 nevitable presence of material losses can be compensated via optical gain.

296 If these delays were not somehow compensated, we would consistently mislocalize moving ob

297 ns) and that the surface potential is better compensated when counterion crowding happens.

298 loss of lutein in heated samples was partly compensated when samples were reheated in the microwave.

299 ave increased energy expenditure that may be compensated with increased food consumption.

300 ency PDs (>2 per second) may be inadequately compensated without an additional rise in CBF and associ