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1 (I/V)FF motif) resulted in the current being completely abolished.
2 ted, furrow formation in the early embryo is completely abolished.
3 nd ADP-glucose pyrophosphorylase, was almost completely abolished.
4 ptake in muscle and adipose cells was almost completely abolished.
5 which CaMKII's activity is specifically and completely abolished.
6 induced p38 phosphorylation by vitamin D was completely abolished.
7 impaired in IL-23p19(-/-) lungs, but was not completely abolished.
8 ransport was significantly decreased but not completely abolished.
9 out pDC, the IFN-alpha response to MHV68 was completely abolished.
10 y mutated, the necrosis-inducing activity is completely abolished.
11 signal-regulated kinase (ERK) signaling was completely abolished.
12 what reduced, but PKCbetaI translocation was completely abolished.
13 acellular Ca(2+), whereas caspase inhibition completely abolished ABT737-induced PS exposure in both
15 ml ricin in DMEM at 121 degrees C for 30 min completely abolished activity; and (c) milk did not affe
16 -/-) mice than in wild-type mice, and almost completely abolished after a pretreatment with amiloride
17 gE and IgG to BGG was confirmed by ELISA and completely abolished after pre-incubation with alpha-gal
20 cific deletion of the L-type VGCC, Ca(v)1.2, completely abolished all lymphatic spontaneous contracti
21 in light intensity, and (3) absence of STN8 completely abolished all PSII core protein phosphorylati
22 BM321, BM322, BM325, and BM326 showed almost completely abolished allergenic activity and induced sig
23 7, also found at the active site, to alanine completely abolished AMP production in our activity assa
24 In the patient's plasma, AP activity was completely abolished and could only be reconstituted wit
25 f helical coiled-coil htt(ex1) tetramers, is completely abolished, and only the pathway resulting in
27 mal models in which oxidative metabolism are completely abolished are not always physiologically or p
28 n contrast, a MEK1/2 inhibitor (ERK pathway) completely abolished arginase II expression while actual
31 R4 mAbs or the anti-human IgE mAb omalizumab completely abolished ATI-induced allergic inflammation.
32 n of carbenoxolone, a PANX1 channel blocker, completely abolished ATP release in Calhm1 knockout cult
34 cing of ATGL expression in adipocytes almost completely abolished basal and TNF-alpha-induced glycero
35 human alphavbeta3 monoclonal antibody LM609, completely abolished binding of ATX to tumor cells, demo
39 topic activity, block of TGF-beta1 signaling completely abolished both arrhythmogenic conditions.
41 tion range (0.1-30 muM) and its effects were completely abolished by a mixture of alpha1- and beta-AR
42 re substantially reduced and, in some cases, completely abolished by administration of neutralizing m
45 ogical defects in er-ant1 plants were nearly completely abolished by application of high environmenta
46 erature on the thermal tolerance of PSII was completely abolished by chloramphenicol, indicating that
47 ally, the EC activation by both bacteria was completely abolished by combined inhibition of TNF and I
48 cular relaxation to acetylcholine, which was completely abolished by endothelial nitric oxide synthas
49 e IFN-gamma-mediated induction of Trim21 was completely abolished by inhibiting protein synthesis wit
50 ments in the AD mice and this protection was completely abolished by inhibiting the dNGIs survival.
51 maltose and maltotriose and the response was completely abolished by introduction of a single point m
52 nticancer/cytotoxic effects of ascorbate are completely abolished by iron at physiological concentrat
54 1R-Abs-induced contraction, which was almost completely abolished by neutralizing peptides targeting
56 pendent growth of MCF-10A(arom) cells can be completely abolished by pre-treatment with the aromatase
59 IgE binding to bromelain (r = 0.68) and was completely abolished by serum preincubation with the CCD
60 sensitive to CysLT1R or EP3 antagonists but completely abolished by simultaneous treatment both in v
61 f spontaneous and miniature IPSCs, an effect completely abolished by the GABAA receptor antagonist ga
64 omyosin regulatory properties of sMyBP-C are completely abolished by the presence of the DA-1 mutatio
67 abrogates CFTR-mediated Cl(-) secretion and completely abolishes cAMP-activated whole cell currents.
69 rutinib, a Tec family kinase inhibitor, also completely abolished CLEC-2-mediated aggregation and Syk
70 (CLEC18A) --> Arg(339) (CLEC18A-1) mutation completely abolishes CLEC18A-1 binding to GLPS-F3, and a
72 ation sites on the C terminus of MORs almost completely abolished desensitization and one measure of
73 the N-terminal dimer swapped helix (aa 1-20) completely abolishes dimerization and severely reduces p
74 Mutagenesis of the tmm gene in R. pomeroyi completely abolished DMS oxidation and subsequent DMSO f
75 s mutation of Arg36 (R36W) or Arg35 (R35H/L) completely abolished DNA binding, mutation of Arg60 (R60
76 shift in the steady-state inactivation curve completely abolished EADs in myocytes while maintaining
77 -NCs) for 3 wk to hairless mouse skin almost completely abolishes EGFR expression, suppresses downstr
79 th in xenografts, attenuation of lipogenesis completely abolished establishment of hepatic metastasis
80 and EGF, because withdrawal of such factors completely abolishes estradiol-induced proliferation.
81 , which selectively cleaves heparan sulfate, completely abolished extracellular TG2 in normal and dis
82 nzyme's N-terminal RING-finger domain almost completely abolishes fiber formation but not cellulose b
83 siRNA-mediated knockdown of both PCs almost completely abolished FLAG-pro-GX sPLA2 processing in Y1
85 s, glycinergic synaptic currents were almost completely abolished following incubation in patient IgG
87 inhibition, but mutating both sites together completely abolished Gem inhibition without affecting Ge
88 alpha4F71L, in alpha4beta1(delta)-receptors completely abolished GHB but not GABA function, indicati
91 loop of phosphorylation site mutants nearly completely abolished HAC1 splicing, induction of KAR2, P
92 athway and amelioration of ER stress in mice completely abolishes high fat diet-induced upregulation
94 results demonstrated that MW thermal heating completely abolished honey antibacterial activity wherea
95 synaptobrevin-2, evoked neurotransmission is completely abolished; however, spontaneous synaptic tran
96 s, we revealed that PIGG activity was almost completely abolished; however, the GPI-APs had normal su
97 expression of single phosphomimic mutations completely abolished HTTex1 aggregation in human cells.
103 ur findings, we verified that a Bim knockout completely abolished immunotoxin-mediated apoptosis.
105 Moreover, ethanol-induced NREM sleep was completely abolished in A2AR knockout mice compared with
106 but reduced in TH+ neurons at 12 months and completely abolished in both TH+ and SST+ neurons by 18
111 e effects of AICAR on Na(+),K(+)-ATPase were completely abolished in cultured primary mouse muscle ce
112 s significantly reduced, however, it was not completely abolished in diabetic PKC-alpha/beta(-/-) mic
113 f the inhibitory tyrosine of SFKs was almost completely abolished in DKO platelets, which was partial
115 mouse models in which ERK/MAPK signaling was completely abolished in each of the two distinct classes
116 kingly, AICAR-induced glycogen synthesis was completely abolished in G6P-insensitive GS knock-in mice
117 L-selectin-dependent leukocyte rolling was completely abolished in Galnt1(-/-) mice compared with w
121 unted and signal from [(13)C]bicarbonate was completely abolished in livers from PEPCK KO mice, indic
122 ated chemokinesis and chemotaxis were almost completely abolished in macrophages lacking Gnai2 (encod
123 ons are independent of Tp53 status, they are completely abolished in mice with germline Fbxw7 haploin
124 kinsonian effects of tropicamide were almost completely abolished in mutant lesioned mice that lack M
127 siglitazone treatment during HFD feeding was completely abolished in Pparg-BKO mice, an effect associ
128 th the specific activity of the enzyme being completely abolished in several TsdA-Cys(96) variants.
129 was markedly reduced in Syb2 (-/-) NMJs and completely abolished in Syb1(lew/lew)Syb2 (-/-) NMJs.
130 und that severing at CMT crossover sites was completely abolished in the Arabidopsis katanin mutant.
131 and F515L) inhibited LDL binding, which was completely abolished in the case of the R496W variant.
134 dramatic stenotic response, which is nearly completely abolished in the immunodeficient SCID/beige (
135 though lignin deposition in roots is almost completely abolished in the lac11 lac4 lac17 triple muta
137 on-mediated enhancement of transcription was completely abolished in the looping defective sua7-1 str
141 eptor agonists in lateral septal neurons was completely abolished in TRPC1/4 double-knockout mice, an
143 ficiency of LC infection is reduced, but not completely abolished, in the absence of the pentameric c
146 Two substitutions, L48F and Y63W, almost completely abolished intracellular virulence gene induct
147 ZFs simultaneously or the complete NC domain completely abolished intracytoplasmic Gag-gRNA interacti
148 ion of the right tonsil, we found (1) nearly completely abolished ipsilateral smooth pursuit and impa
149 ependent remodeling, cholinergic stimulation completely abolished isoproterenol-induced triggered act
153 the two predicted PKGI phosphorylation sites completely abolished its basal phosphorylation by PKGI.
155 the 4-residue CTV from Escherichia coli FtsZ completely abolished lateral interactions between chimer
158 te) of the cardiac ryanodine receptor (RyR2) completely abolishes luminal, but not cytosolic, Ca(2+)
159 1 to M-CSF dramatically reduces but does not completely abolish M-CSF binding and signaling through i
161 ssion of ERalpha in the preoptic area almost completely abolished maternal care, significantly increa
162 ogic inhibition and genetic knockout of TLR4 completely abolished ML exosome-induced cytokine product
163 eletion of myomaker in adult satellite cells completely abolishes muscle regeneration, resulting in s
165 omyelinase by NB-19 before addition of POVPC completely abolished nanoplatform disintegration by oxPL
167 ctive antagonist alpha-conotoxin AuIB almost completely abolished nicotine-evoked currents in mHb neu
168 The NPY Y1 receptor antagonist BIBO3304 completely abolished NPY effects on fear extinction retr
173 il extravasation elicited by CCL3 was almost completely abolished on inhibition of G protein-receptor
175 ut not cytochromes bo(3) and bd-II) also had completely abolished PGRP-induced H(2)O(2) production an
176 neutrophils toward C. neoformans but almost completely abolished phagocytosis and killing of the org
178 signal peptides simultaneously was found to completely abolish physiological tetrathionate reductase
179 r targeted to the ER surface (termed p4PKIg) completely abolished PKA-mediated augmentation of HERG i
180 y loop, and deletion of the regulatory loop, completely abolished processing capacity of the mutants.
181 mals were strongly reduced along with almost completely abolished production of IL-17A, IFN-gamma, an
182 RORbeta, and point mutations in these sites completely abolish promoter activity in living retinas.
184 h thymidine kinase-deficient HSV-1 (TK(del)) completely abolished reactivation of wild-type (WT) supe
187 nated with CyaA-E7, rapamycin administration completely abolished recruitment of CD8+ T cells into TC
188 n of the first residue of the 3'-CCUGU motif completely abolished replication initiation, suggesting
189 ibition of alpha-glucosidase activity almost completely abolished residual glucose production by G6pc
190 (3HKYN) to 3-hydroxyanthranilic acid (3HAA), completely abolished RQ biosynthesis but did not affect
192 ccordingly, siRNA knockdown of Rac1 or Cdc42 completely abolished Smk-induced cell migration, whereas
196 n the activation loop decreased, but did not completely abolish, splicing of HAC1 mRNA, induction of
198 t four residues of the ETON region or beyond completely abolished STIM1-dependent Orai1 function.
199 h a homozygous R429C point mutation in STIM1 completely abolishing store-operated calcium entry in T
202 EB1, the metabolic activity was increased or completely abolished, suggesting that GREB1 may function
203 oordination site of the endopeptidase domain completely abolished SXN101742 inhibitory actions on GH
204 GS7 does not reconfigure the GAP complex and completely abolishes synaptic transmission, resulting in
206 talytically important core and CR4/5 domains completely abolish telomerase activity, unveiling mechan
207 dor-SN protein (MEF-KO) affects but does not completely abolish the association of PPARgamma and aP2-
208 2 weeks of detraining is not long enough to completely abolish the beneficial effects of regular exe
209 contrast, syt(-/-); cpx(-/-) double mutants completely abolish the enhanced spontaneous release obse
210 weakening of activity was powerful enough to completely abolish the hyperactivity induced by intense
211 in plant hormone signaling pathways did not completely abolish the transcript response but hinted at
212 roduction by donor T cells was sufficient to completely abolish the Treg suppressive effect in GVHD.
213 on using a lentivirus harboring shRNA almost completely abolished the ability of Klotho to rescue neu
214 btlest mutations either severely impaired or completely abolished the ability of the replicon to repl
215 namic injection of cytokine-encoding plasmid completely abolished the accumulation of promonocytes in
218 f resting SG Ca(2+) by approximately 75% and completely abolished the ATP-mediated release of Ca(2+)
220 Blocking of IFN-gamma with specific mAb completely abolished the beneficial effect of donor Treg
221 change of valine to alanine at position 135 completely abolished the binding of LPS to the hMD-2 mut
222 mediated CCL2 knockdown in endothelial cells completely abolished the blood-brain barrier protective
223 ivity, selective inhibition of alpha3 almost completely abolished the capacity to restore [Na(+)](i)
224 reas blockade of IL-7Ralpha signaling almost completely abolished the development of primary SS, base
227 necrosis factor alpha in the hippocampus and completely abolished the effect of peripheral inflammati
228 The cyclooxygenase inhibitor indomethacin completely abolished the effects of nicotinic acid indic
230 eover, mutations in residue NqrB-G140 almost completely abolished the electron transfer to ubiquinone
231 e significantly increased basal activity and completely abolished the ethanol-induced activity of the
233 dy binding to the dimerization arm of ErbB2, completely abolished the formation of constitutive and H
235 RNA-mediated suppression of CD146 expression completely abolished the galectin-3-induced secretion of
236 e selection eliminated Runx3d expression and completely abolished the generation of CD8(+) single-pos
239 WT-20 disordered the L(alpha) phase and completely abolished the HII phase in DOPE-Me/WT-20 50:1
240 Hippocampal suppression of HDAC4 in vivo completely abolished the long-lasting AChE-related and b
241 the lysosomal association of mTOR and almost completely abolished the lysosomal association of TSC2.
242 SRC kinase inhibitor, saracatinib (AZD0530), completely abolished the MEK inhibitor-induced invasion.
243 (+) cells from reprogramming cultures almost completely abolished the NANOG and OCT4 positive sub-pop
245 ver, transient inhibition of mTORC2 by PP242 completely abolished the phosphorylation of 4EBP1 and de
246 acologic inhibition of glycolytic metabolism completely abolished the protection afforded the heart b
247 cule, did not affect the ATPase activity but completely abolished the replication and transcription o
248 two RAREs, DE-RARE and ENE-RARE, in the BAC completely abolished the rostral expansion of the 5 Hoxb
250 iting 53BP1 recruitment to damaged chromatin completely abolished the survival advantage after multif
251 studies demonstrated that regulatory T cells completely abolished the tPA-induced elevation of MMP9 a
252 of the promoter activity, but neither mutant completely abolished the TX-induced GLT-1 promoter activ
254 rival at the intercellular bridge but almost completely abolishes the abscission failure phenotype.
255 s (Glu(200) and Glu(414)) of the active site completely abolishes the beta-glucosidase activity.
256 er glycine residue in the two Axin segments, completely abolishes the binding of the corresponding Ax
257 utation of Trp(233) to phenylalanine (W233F) completely abolishes the Cc-dependent peroxidase activit
258 XP3(+) Treg cells during tolerance induction completely abolishes the development of LZT, resulting i
259 deletion of both Grin2a and exon 5 of Grin1 completely abolishes the developmental change in NMDAR-E
260 blocking Notch signaling in late RPCs almost completely abolishes the generation of terminal asymmetr
261 ecause the systemic depletion of neutrophils completely abolishes the nanoparticle tumor deposition.
262 domain with a (GGS)(10) unstructured linker completely abolishes the phosphorylation of all tyrosine
265 encing or eliminating the remodelled circuit completely abolishes the recovered proprioceptive functi
266 segment in the protein tag to 18 amino acids completely abolishes the RNA binding function of dsRBD.
267 Consequently, neutralization of IFN-gamma completely abolishes the suppressive capacity of this po
268 onatal amygdala damage retarded, but did not completely abolish, the acquisition of a learned fear.
269 /me3 spread, impairs cell proliferation, and completely abolishes their capacity to form tumors in mi
270 e knock-down of a Peg3 ortholog in zebrafish completely abolishes their expression, resulting in a 2-
272 tory cortex during the priming period almost completely abolished these improvements, suggesting that
273 tion that even relatively modest disruptions completely abolish this anti-viral activity shows that t
274 ing the O. formigenes CM with heat or pepsin completely abolished this bioactivity, and selective ult
278 es, whereas blockade of VIP receptors almost completely abolished this form of epileptiform activity.
281 oR-Hdac3 interaction alone was sufficient to completely abolish TLR4 tolerance and to render mice vul
284 oline substitutions on the PC1-proximal side completely abolished transport and reduced backbone flex
290 hown that deletion of either nrdHEKF or nrdI completely abolishes virulence in an animal model of end
292 ated GIP, GLP-1 and PYY secretion, which was completely abolished when extracellular Ca2+ was absent.
296 ux (100 nm) in cultured DRG neurons that was completely abolished when TRPA1 was deleted or inhibited
297 oter region, and the repressive function was completely abolished when WT1 binding sites were mutated
298 Subsequently, GnRH receptor activation was completely abolished with a selective Galphaq inhibitor,
300 ndent on alpha-catenin; the rescue effect is completely abolished with the depletion of alpha-catenin